Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P05019

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
21	unknown peptidase	1-195	P		NT	<%Agarwal et al., 2012[]%>
48	unknown peptidase	1-195	P		NT	<%Agarwal et al., 2012[]%>
118	unknown peptidase	1-195	P		NT	<%Agarwal et al., 2012[]%>
119	furin	114-123	N		CS	Remacle et al., 2008
119	PCSK2 peptidase	114-123	N		CS	Remacle et al., 2008
119	PCSK4 peptidase	114-123	N		CS	Remacle et al., 2008
119	PCSK6 peptidase	114-123	N		CS	Remacle et al., 2008
119	PCSK5 peptidase	114-123	N		CS	Remacle et al., 2008
119	PCSK7 peptidase	114-123	N		CS	Remacle et al., 2008