Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P01323

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site Peptidase Residue range Cleavage type Description Evidence Reference
24 unknown peptidase 1-110 P release of a signal peptide NT Steiner et al., 1969
56 PCSK1 peptidase 25-110 P Irminger et al., 1997
56 PCSK2 peptidase 25-110 P Irminger et al., 1997
87 unknown peptidase 1-110 P NT <%Agarwal et al., 2012[]%>
89 PCSK1 peptidase 25-110 P Irminger et al., 1997
89 PCSK2 peptidase 25-110 P Irminger et al., 1997