Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P01161

,

Click here to display alignment and conservation of cleavage sites of this sequence with close homologues. This will take a few moments.

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
24	unknown peptidase	1-152	P		NT	<%Agarwal et al., 2012[]%>
122	unknown peptidase	1-152	P		NT	<%Agarwal et al., 2012[]%>
125	insulysin	122-150	P			Müller et al., 1992
125	oligopeptidase B	123-150	N			Morty et al., 2005
126	oligopeptidase B	123-150	N			Morty et al., 2005
129	insulysin	122-150	P			Müller et al., 1992
133	oligopeptidase B	123-150	N			Morty et al., 2005
135	insulysin	122-150	P			Müller et al., 1992
147	neprilysin-2	123-150	N		NT	Rose et al., 2002
147	insulysin	122-150	P			Müller et al., 1992
149	oligopeptidase B	123-150	N			Morty et al., 2005