Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P00711

,

Click here to display alignment and conservation of cleavage sites of this sequence with close homologues. This will take a few moments.

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
19	phytepsin	1-142	N		NT	Barros & Malcata, 2006
19	unknown peptidase	1-142	P	release of a signal peptide	NT
25	unknown peptidase	20-142	P		NT	Beck et al., 2001
28	phytepsin	1-142	N			Barros & Malcata, 2006
30	phytepsin	1-142	N		NT	Barros & Malcata, 2006
32	unknown peptidase	20-142	P		NT	Beck et al., 2001
37	phytepsin	1-142	N		NT	Barros & Malcata, 2006
45	phytepsin	1-142	N		NT	Barros & Malcata, 2006
50	phytepsin	1-142	N		NT	Barros & Malcata, 2006
50	chymotrypsin A (cattle-type)	20-142	N			Polverino de Laureto et al., 1999
53	endopeptidase K	20-142	N			Polverino de Laureto et al., 1999
54	phytepsin	1-142	N		NT	Barros & Malcata, 2006
56	unknown peptidase	20-142	P		NT	Beck et al., 2001
57	unknown peptidase	20-142	P		NT	Beck et al., 2001
58	endopeptidase K	20-142	N			Polverino de Laureto et al., 1999
59	pepsin A	20-142	N			Polverino de Laureto et al., 1999
59	phytepsin	1-142	N		NT	Barros & Malcata, 2006
61	unknown peptidase	20-142	P		NT	Beck et al., 2001
62	endopeptidase K	20-142	N			Polverino de Laureto et al., 1999
63	legumain, animal-type	20-142	P	normal turnover		Beck et al., 2001
64	legumain, animal-type	20-142	P	normal turnover		Beck et al., 2001
65	unknown peptidase	20-142	P		NT	Beck et al., 2001
66	phytepsin	1-142	N		NT	Barros & Malcata, 2006
69	chymotrypsin A (cattle-type)	20-142	N			Polverino de Laureto et al., 1999
71	pepsin A	20-142	N			Polverino de Laureto et al., 1999
71	phytepsin	1-142	N		NT	Barros & Malcata, 2006
72	phytepsin	1-142	N		NT	Barros & Malcata, 2006
72	chymotrypsin A (cattle-type)	20-142	N			Polverino de Laureto et al., 1999
72	endopeptidase K	20-142	N			Polverino de Laureto et al., 1999
73	phytepsin	1-142	N		NT	Barros & Malcata, 2006
75	legumain, animal-type	20-142	P	normal turnover		Beck et al., 2001
75	endopeptidase K	20-142	N			Polverino de Laureto et al., 1999
76	legumain, animal-type	20-142	P	normal turnover		Beck et al., 2001
77	unknown peptidase	20-142	P		NT	Beck et al., 2001
78	phytepsin	1-142	N		NT	Barros & Malcata, 2006
79	unknown peptidase	20-142	P		NT	Beck et al., 2001
90	legumain, animal-type	20-142	P	normal turnover		Beck et al., 2001
93	legumain, animal-type	20-142	P	normal turnover		Beck et al., 2001
95	unknown peptidase	20-142	P		NT	Beck et al., 2001
99	unknown peptidase	20-142	P		NT	Beck et al., 2001
104	phytepsin	1-142	N		NT	Barros & Malcata, 2006
114	endopeptidase K	20-142	N			Polverino de Laureto et al., 1999
115	phytepsin	1-142	N		NT	Barros & Malcata, 2006
117	endopeptidase K	20-142	N			Polverino de Laureto et al., 1999
121	legumain, animal-type	20-142	P	normal turnover		Beck et al., 2001
122	pepsin A	20-142	N			Polverino de Laureto et al., 1999
123	chymotrypsin A (cattle-type)	20-142	N			Polverino de Laureto et al., 1999
124	phytepsin	1-142	N		NT	Barros & Malcata, 2006