Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence O75367

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-372	P		NT	<%Agarwal et al., 2012[]%>
4	granzyme A	1-372	N			Van Damme et al., 2010
83	astacin	80-96	N		MS	Becker-Pauly et al., 2011
125	astacin	122-135	N		MS	Becker-Pauly et al., 2011
125	meprin alpha subunit	122-135	N		MS	Becker-Pauly et al., 2011
172	granzyme B (Homo sapiens-type)	2-372	N		MS	Van Damme et al., 2010
277	LAST peptidase (Limulus-type)	274-292	N		MS	Becker-Pauly et al., 2011
281	astacin	278-292	N		MS	Becker-Pauly et al., 2011