Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence O56140

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
16	unknown peptidase	1-568	P		NT	<%Agarwal et al., 2012[]%>
338	unknown peptidase	1-568	P		NT	<%Agarwal et al., 2012[]%>
346	furin	341-350	N		CS	Remacle et al., 2008
346	PCSK2 peptidase	341-350	N		CS	Remacle et al., 2008
346	PCSK4 peptidase	341-350	N		CS	Remacle et al., 2008
346	PCSK6 peptidase	341-350	N		CS	Remacle et al., 2008
346	PCSK5 peptidase	341-350	N		CS	Remacle et al., 2008
346	PCSK7 peptidase	341-350	N		CS	Remacle et al., 2008