Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence O43915

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
21	unknown peptidase	1-354	P		NT	<%Agarwal et al., 2012[]%>
88	plasmin	22-354	P			McColl et al., 2003
88	furin	22-354	P			McColl et al., 2007
88	PCSK5 peptidase	22-354	P			McColl et al., 2007
99	furin	89-205	P			McColl et al., 2007
100	plasmin	22-354	P			McColl et al., 2003
205	plasmin	22-354	P			McColl et al., 2003
205	furin	22-354	P			McColl et al., 2007
205	PCSK5 peptidase	22-354	P			McColl et al., 2007
205	PCSK7 peptidase	22-354	P			McColl et al., 2007