Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence O14672

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
19	unknown peptidase	1-748	P		NT	<%Agarwal et al., 2012[]%>
109	meprin beta subunit	20-748	N		MS	Becker-Pauly et al., 2011
213	furin	20-748	P			Anders et al., 2001
213	PCSK2 peptidase	208-217	N		CS	Remacle et al., 2008
213	PCSK4 peptidase	208-217	N		CS	Remacle et al., 2008
213	PCSK6 peptidase	208-217	N		CS	Remacle et al., 2008
213	PCSK5 peptidase	208-217	N		CS	Remacle et al., 2008
213	PCSK7 peptidase	20-748	P			Anders et al., 2001