Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence O14617

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-1153	P	release of an initiating methionine	MS	Flikka et al., 2006
201	LAST_MAM peptidase (Limulus-type)	198-212	N		MS	Becker-Pauly et al., 2011
588	trypsin 1	1-1153	N		MS	Schilling & Overall, 2008
610	trypsin 1	1-1153	N		MS	Schilling & Overall, 2008
708	granzyme B (Homo sapiens-type)	1-1153	N		MS	Van Damme et al., 2010
722	granzyme B (Homo sapiens-type)	1-1153	N		MS	Van Damme et al., 2010
800	trypsin 1	1-1153	N		MS	Schilling & Overall, 2008
806	LAST_MAM peptidase (Limulus-type)	803-820	N		MS	Becker-Pauly et al., 2011
815	trypsin 1	1-1153	N		MS	Schilling & Overall, 2008