Sequence features for peptidase S01.213: coagulation factor XIa

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

MERNUM	Species	Sequence length	Peptidase unit	Active site residues	Source
MER0690129	Acanthisitta chloris	530	301-528	H341, D386, S481,	GENBANK:XP_009075342
MER0330597	Anas platyrhynchos	628	393-627	H436, D485, S580	GENBANK:XP_005009027
MER0397428	Balaenoptera acutorostrata	625	388-624	H431, D480, S575	GENBANK:XP_007174042
MER0679260	Bison bison	625	388-623	H431, D480, S575	GENBANK:XP_010834113
MER0380873	Bos grunniens	625	388-620	H431, D480, S575	GENBANK:ELR54070
MER0003604	Bos taurus	131	1-131	missing, missing, S81	UNIPROT:P79131
MER0003604	Bos taurus	131	1-131	missing, missing, S81	UNIPROT:P79131
MER0077829	Bos taurus	625	388-623	H431, D480, S575	UNIPROT:Q5NTB3
MER0077829	Bos taurus	625	388-623	H431, D480, S575	UNIPROT:Q5NTB3
MER0581419	Bubalus bubalis	625	388-623	H431, D480, S575	GENBANK:XP_006060352
MER0267560	Callithrix jacchus	625	388-625	H431, D480, S575	UNIPROT:F6ZZG6
MER0267560	Callithrix jacchus	625	388-625	H431, D480, S575	UNIPROT:F6ZZG6
MER0582568	Calypte anna	623	393-622	H436, D485, S575	GENBANK:XP_008490072
MER0677983	Camelus dromedarius	624	387-623	H430, D479, S574	GENBANK:XP_010994033
MER0268860	Camelus ferus	625	388-624	H431, D480, S575	GENBANK:XP_006178431
MER0138953	Canis lupus familiaris	624	387-624	H430, D479, S574	UNIPROT:B5LX43
MER0138953	Canis lupus familiaris	624	387-624	H430, D479, S574	UNIPROT:B5LX43
MER0555650	Capra hircus	625	388-623	H431, D480, S575	GENBANK:XP_005698802
MER0103791	Cavia porcellus	632	388-620	H431, D480, S575	GENBANK:XP_003469209
MER0522046	Ceratotherium simum	631	387-631	H426, D475, S579	GENBANK:XP_004428522
MER0522628	Ceratotherium simum	625	388-624	H431, D480, S575	GENBANK:XP_004428827
MER0584810	Cercopithecus sabaeus	625	388-624	H431, D480, S575	GENBANK:XP_007998681
MER0582858	Chinchilla lanigera	625	388-625	H431, D480, S575	GENBANK:XP_005373486
MER0575018	Chrysochloris asiatica	627	390-626	H433, D482, S577	GENBANK:XP_006834518
MER0670828	Colobus angolensis	625	388-624	H431, D480, S575	GENBANK:XP_011814903
MER0378564	Columba livia	609	374-604	H417, D466, S561	GENBANK:EMC80621
MER0574482	Condylura cristata	625	388-623	H431, D480, S575	GENBANK:XP_004682554
MER0573209	Corvus brachyrhynchos	627	392-626	H435, D484, S579	GENBANK:XP_008639674
MER0301387	Cricetulus griseus	642	405-635	H448, D497, S592	GENBANK:XP_003507510
MER0216497	Drosophila grimshawi	588	323-566	H370, D416, S517	GENBANK:XP_001983487
MER0216455	Drosophila willistoni	601	356-599	H403, D449, S549	GENBANK:XP_002068219
MER0216687	Drosophila yakuba	570	323-570	H370, D416, S516	GENBANK:XP_002093649
MER0098342	Equus caballus	615	378-614	H421, D470, S565	GENBANK:XP_001490330
MER0561337	Equus przewalskii	625	388-624	H431, D480, S575	GENBANK:XP_008508352
MER0559883	Falco cherrug	628	393-627	H436, D485, S580	GENBANK:XP_005433833
MER0545901	Falco peregrinus	628	393-627	H436, D485, S580	GENBANK:XP_005243200
MER0379641	Felis catus	625	388-624	H431, D480, S575	UNIPROT:M3VWV2
MER0379641	Felis catus	625	388-624	H431, D480, S575	UNIPROT:M3VWV2
MER0569519	Ficedula albicollis	627	392-626	H435, D484, S579	GENBANK:XP_005045214
MER0657749	Fopius arisanus	569	326-565	H370, D425, S521	GENBANK:XP_011302926
MER0655412	Fukomys damarensis	625	388-625	H431, D480, S575	GENBANK:XP_010618087
MER0054128	Gallus gallus	664	429-663	H472, D521, S616	UNIPROT:F1NUN5
MER0054128	Gallus gallus	664	429-663	H472, D521, S616	UNIPROT:F1NUN5
MER0559093	Geospiza fortis	805	565-799	H608, D657, S752	GENBANK:XP_005415733
MER0388751	Gorilla gorilla	582	388-581	H431, D480, S532	GENBANK:XP_004040776
MER0264397	Heterocephalus glaber	564	327-559	H370, D419, S514	UNIPROT:G5BNV1
MER0264397	Heterocephalus glaber	564	327-559	H370, D419, S514	UNIPROT:G5BNV1
MER0000210	Homo sapiens	625	388-625	H431, D480, S575	GENBANK:XP_005262880
MER0000210	Homo sapiens	625	388-625	H431, D480, S575	GENBANK:XP_005262880
MER0000210	Homo sapiens	625	388-625	H431, D480, S575	GENBANK:XP_005262880
MER0000210	Homo sapiens	625	388-625	H431, D480, S575	GENBANK:XP_005262880
MER0000210	Homo sapiens	625	388-625	H431, D480, S575	GENBANK:XP_005262880
MER0000210	Homo sapiens	625	388-625	H431, D480, S575	GENBANK:XP_005262880
MER0547435	Jaculus jaculus	625	388-625	H431, D480, S575	GENBANK:XP_004666428
MER0552813	Leptonychotes weddellii	636	399-636	H442, D491, S586	GENBANK:XP_006741889
MER0549837	Lipotes vexillifer	625	388-624	H431, D480, S575	GENBANK:XP_007466613
MER0266482	Macaca fascicularis	624	388-624	H431, D480, S575	UNIPROT:G7PKF5
MER0266482	Macaca fascicularis	624	388-624	H431, D480, S575	UNIPROT:G7PKF5
MER0266583	Macaca mulatta	624	388-624	H431, D480, S575	UNIPROT:G7MSF8
MER0266583	Macaca mulatta	624	388-624	H431, D480, S575	UNIPROT:G7MSF8
MER0645322	Mandrillus leucophaeus	625	388-624	H431, D480, S575	GENBANK:XP_011836169
MER0301401	Meleagris gallopavo	719	399-629	H442, D491, S586	GENBANK:XP_003205826
MER0540947	Melopsittacus undulatus	620	394-619	H437, D486, S572	GENBANK:XP_005149112
MER0545239	Mesocricetus auratus	627	390-627	H433, D482, S577	GENBANK:XP_005066710
MER0538640	Microtus ochrogaster	628	391-628	H434, D483, S578	GENBANK:XP_005362704
MER0099554	Monodelphis domestica	625	389-623	H432, D481, S576	GENBANK:XP_001368290
MER0016223	Mus musculus	624	390-624	H430, D479, S574	GENBANK:BAB24114
MER0016223	Mus musculus	624	390-624	H430, D479, S574	GENBANK:BAB24114
MER0016223	Mus musculus	624	390-624	H430, D479, S574	GENBANK:BAB24114
MER0016223	Mus musculus	624	390-624	H430, D479, S574	GENBANK:BAB24114
MER0601229	Mustela putorius	636	399-636	H442, D491, S586	UNIPROT:M3YFX5
MER0601229	Mustela putorius	636	399-636	H442, D491, S586	UNIPROT:M3YFX5
MER0532354	Octodon degus	619	382-619	H425, D474, S569	GENBANK:XP_004639867
MER0530459	Odobenus rosmarus	636	399-636	H442, D491, S586	GENBANK:XP_004417422
MER0529764	Orcinus orca	633	388-624	H431, D480, S575	GENBANK:XP_004277238
MER0528674	Orycteropus afer	633	396-632	H439, D488, S583	GENBANK:XP_007946583
MER0016224	Oryctolagus cuniculus	624	387-624	H430, D479, S574	GENBANK:NP_001076261
MER0364876	Otolemur garnettii	625	388-625	H431, D480, S575	GENBANK:XP_003792872
MER0365399	Otolemur garnettii	549	327-545	H358, D403, S499	GENBANK:XP_003801036
MER0379578	Ovis aries	625	388-620	H431, D480, S575	UNIPROT:W5PEM0
MER0379578	Ovis aries	625	388-620	H431, D480, S575	UNIPROT:W5PEM0
MER0399372	Pan paniscus	625	388-593	H431, D480, E543	GENBANK:XP_003823541
MER0099548	Pan troglodytes	593	388-593	H431, D480, S543	GENBANK:XP_517566
MER0519521	Panthera tigris	625	388-625	H431, D480, S575	GENBANK:XP_007099050
MER0517388	Pantholops hodgsonii	625	388-623	H431, D480, S575	GENBANK:XP_005972629
MER0378231	Papio anubis	625	388-625	H431, D480, S575	UNIPROT:A0A096NC95
MER0378231	Papio anubis	625	388-625	H431, D480, S575	UNIPROT:A0A096NC95
MER0524824	Pelodiscus sinensis	623	388-622	H431, D480, S575	UNIPROT:K7FLF2
MER0524824	Pelodiscus sinensis	623	388-622	H431, D480, S575	UNIPROT:K7FLF2
MER0519706	Physeter catodon	625	388-624	H431, D480, S575	GENBANK:XP_007126520
MER0607394	Plutella xylostella	730	476-719	H522, D572, S673	GENBANK:XP_011555251
MER0267137	Pongo abelii	625	388-624	H431, D480, S575	UNIPROT:H2PEX7
MER0267137	Pongo abelii	625	388-624	H431, D480, S575	UNIPROT:H2PEX7
MER0028202	Rattus norvegicus	590	339-590	H379, D445, S540	GENBANK:XP_224872
MER0557863	Rhinopithecus roxellana	625	388-624	H431, D480, S575	GENBANK:XP_010376290
MER0378196	Saimiri boliviensis	625	388-625	H431, D480, S575	GENBANK:XP_003933870
MER0104851	Sorex araneus	624	388-623	H431, D480, S575	GENBANK:XP_004610458
MER0206057	Taeniopygia guttata	627	400-630	P443, E492, H587	GENBANK:XP_002191090
MER0596141	Tarsius syrichta	625	388-624	H431, D480, S575	GENBANK:XP_008067645
MER0480161	Trichechus manatus	625	388-624	H431, D480, S575	GENBANK:XP_004382857
MER0598321	Tupaia chinensis	631	387-623	H430, D479, S574	GENBANK:XP_006160530
MER0616902	Vicugna pacos	622	385-621	H428, D477, S572	GENBANK:XP_006198143