Sequence features for peptidase S01.147: granzyme H

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

MERNUM	Species	Sequence length	Peptidase unit	Active site residues	Source
MER0216297	Ailuropoda melanoleuca	246	21-245	H64, D108, S202	GENBANK:XP_002921073
MER0398879	Balaenoptera acutorostrata	250	25-250	H68, D112, S206	GENBANK:XP_007180716
MER0433229	Bos grunniens	250	25-250	H68, D112, S206	GENBANK:XP_005904947
MER0213982	Bos taurus	245	20-245	H63, D107, S201	GENBANK:XP_874639
MER0579573	Bubalus bubalis	160	21-158	H64, D108, S116	GENBANK:XP_006055228
MER0518081	Camelus ferus	158	19-156	H62, D106, S114	GENBANK:XP_006182889
MER0518157	Camelus ferus	244	19-244	H62, D106, S200	GENBANK:XP_006182887
MER0056360	Canis lupus familiaris	250	21-250	H68, D112, S206	GENBANK:XP_547751
MER0526336	Capra hircus	250	25-250	H68, N112, S206	GENBANK:XP_005701618
MER0526338	Capra hircus	164	25-163	H68, N112, S120	GENBANK:XP_005701621
MER0526340	Capra hircus	244	24-244	H62, N106, S200	GENBANK:XP_005701619
MER0270671	Cavia porcellus	245	23-244	H66, D110, S201	GENBANK:XP_005008541
MER0367676	Cavia porcellus	246	20-243	H63, D107, S202	GENBANK:XP_003460842
MER0368125	Cavia porcellus	245	20-242	H62, D106, S201	GENBANK:XP_003460846
MER0486897	Cavia porcellus	387	161-384	H204, missing, D60, D248, missing, S343	GENBANK:XP_003460843
MER0486916	Cavia porcellus	393	325-391	missing, H61, D105, missing, S206, S349	GENBANK:XP_003464816
MER0486923	Cavia porcellus	252	26-249	H69, D113, S208	GENBANK:XP_003474327
MER0486924	Cavia porcellus	246	20-243	H63, D107, S202	GENBANK:XP_003474329
MER0537316	Ceratotherium simum	158	21-157	H64, D106, S114	GENBANK:XP_004421215
MER0587656	Cercopithecus sabaeus	246	21-246	H64, D108, S202	GENBANK:XP_007984545
MER0583013	Chinchilla lanigera	160	21-159	H64, D108, S116	GENBANK:XP_005377045
MER0576046	Chrysemys picta	203	1-201	H16, D60, S159	GENBANK:XP_008176389
MER0578276	Chrysemys picta	248	24-245	H67, D111, S203	GENBANK:XP_008174866
MER0575046	Chrysochloris asiatica	251	21-245	H63, D107, S201	GENBANK:XP_006835570
MER0575051	Chrysochloris asiatica	250	21-244	H63, D107, S200	GENBANK:XP_006835574
MER0575053	Chrysochloris asiatica	250	21-241	H63, D107, S200	GENBANK:XP_006835576
MER0573889	Condylura cristata	321	119-321	H162, D204, S298	GENBANK:XP_004694573
MER0605556	Dasypus novemcinctus	246	21-246	H64, D108, S202	GENBANK:XP_004477526
MER0565091	Elephantulus edwardii	251	21-245	H64, D108, S201	GENBANK:XP_006890048
MER0565092	Elephantulus edwardii	251	21-245	H64, D108, S201	GENBANK:XP_006890049
MER0565529	Elephantulus edwardii	217	1-211	H30, D74, S167	GENBANK:XP_006903121
MER0565530	Elephantulus edwardii	245	15-239	H58, D102, S195	GENBANK:XP_006903122
MER0565533	Elephantulus edwardii	252	22-246	H65, D109, S202	GENBANK:XP_006903125
MER0565537	Elephantulus edwardii	251	21-245	H64, D108, S201	GENBANK:XP_006903129
MER0565540	Elephantulus edwardii	264	30-246	H64, D108, S204	GENBANK:XP_006903213
MER0565544	Elephantulus edwardii	234	4-228	H47, D91, S184	GENBANK:XP_006903217
MER0565545	Elephantulus edwardii	252	22-246	H65, D109, S202	GENBANK:XP_006903218
MER0565547	Elephantulus edwardii	263	33-257	H76, D120, S213	GENBANK:XP_006903220
MER0563590	Eptesicus fuscus	239	2-227	H45, D89, S183	GENBANK:XP_008159989
MER0564227	Eptesicus fuscus	247	21-242	H63, D105, S199	GENBANK:XP_008151154
MER0098274	Equus caballus	245	21-242	H64, D108, S200	GENBANK:XP_001488445
MER0098296	Equus caballus	250	20-245	A63, N107, D201	GENBANK:XP_001488857
MER0098298	Equus caballus	248	21-245	H64, D109, S203	GENBANK:XP_001488900
MER0098571	Equus caballus	395	20-248	H63, D107, S206	GENBANK:XP_001497398
MER0241084	Equus caballus	243	34-241	H77, G121, S199	GENBANK:XP_001917560
MER0562037	Equus przewalskii	261	25-244	H64, N108, S202	GENBANK:XP_008533674
MER0562040	Equus przewalskii	248	25-245	H64, D109, S203	GENBANK:XP_008533675
MER0099007	Felis catus	303	21-243	H64, D108, S202	GENBANK:XP_003987619
MER0558302	Galeopterus variegatus	251	21-243	H64, D108, S201	GENBANK:XP_008571835
MER0609560	Gorilla gorilla	160	21-159	H64, D108, S116	GENBANK:XP_004055080
MER0609563	Gorilla gorilla	246	21-246	H64, D108, S202	UNIPROT:G3R9N9
MER0609563	Gorilla gorilla	246	21-246	H64, D108, S202	UNIPROT:G3R9N9
MER0486052	Heterocephalus glaber	246	22-244	H64, D108, S202	GENBANK:EHB11955
MER0000166	Homo sapiens	246	21-246	H64, D108, S202	GENBANK:ABM82994
MER0000166	Homo sapiens	246	21-246	H64, D108, S202	GENBANK:ABM82994
MER0000166	Homo sapiens	246	21-246	H64, D108, S202	GENBANK:ABM82994
MER0000166	Homo sapiens	246	21-246	H64, D108, S202	GENBANK:ABM82994
MER0000166	Homo sapiens	246	21-246	H64, D108, S202	GENBANK:ABM82994
MER0611684	Latimeria chalumnae	214	1-208	H30, D73, S169	GENBANK:XP_005996400
MER0553208	Leptonychotes weddellii	160	21-160	H64, D108, S116	GENBANK:XP_006748319
MER0553211	Leptonychotes weddellii	246	21-246	H64, D108, S202	GENBANK:XP_006748317
MER0548579	Lipotes vexillifer	261	25-250	H68, D112, P206	GENBANK:XP_007471899
MER0102963	Loxodonta africana	256	25-243	H64, D108, S202	GENBANK:XP_003421065
MER0258819	Loxodonta africana	251	21-243	H63, D107, S201	GENBANK:XP_003408931
MER0399484	Macaca fascicularis	246	21-243	H64, D108, S202	UNIPROT:G7PA01
MER0399484	Macaca fascicularis	246	21-243	H64, D108, S202	UNIPROT:G7PA01
MER0603766	Macaca fascicularis	160	21-158	H64, D108, S116	GENBANK:XP_005561053
MER0367712	Macaca mulatta	246	21-243	H64, D108, S202	UNIPROT:G7MXD6
MER0367712	Macaca mulatta	246	21-243	H64, D108, S202	UNIPROT:G7MXD6
MER0562584	Myotis brandtii	249	21-242	H63, D105, S199	GENBANK:XP_005863434
MER0576683	Myotis brandtii	249	21-242	H63, D105, S199	GENBANK:XP_005857330
MER0614122	Myotis davidii	249	21-242	H63, D105, S199	GENBANK:XP_006760934
MER0125603	Myotis lucifugus	249	21-242	H63, D105, S199	UNIPROT:G1PAW9
MER0125603	Myotis lucifugus	249	21-242	H63, D105, S199	UNIPROT:G1PAW9
MER0257053	Nomascus leucogenys	274	51-271	H94, D138, S230	GENBANK:XP_003261000
MER0533839	Ochotona princeps	245	21-245	H63, D107, S201	GENBANK:XP_004584985
MER0532092	Octodon degus	246	21-246	H64, D108, S202	GENBANK:XP_004645127
MER0531733	Odobenus rosmarus	246	21-246	H64, D108, S202	GENBANK:XP_004402073
MER0531735	Odobenus rosmarus	160	21-159	H64, D108, S116	GENBANK:XP_004402075
MER0530153	Orcinus orca	261	25-250	H68, D112, S206	GENBANK:XP_004283157
MER0528703	Orycteropus afer	262	21-245	H64, D108, S202	GENBANK:XP_007947452
MER0528706	Orycteropus afer	251	21-245	H64, D108, S201	GENBANK:XP_007947455
MER0110454	Oryctolagus cuniculus	244	20-244	H62, D106, S200	GENBANK:XP_002717972
MER0603917	Oryctolagus cuniculus	161	21-159	H64, D108, S116	GENBANK:XP_008267679
MER0366555	Otolemur garnettii	262	34-255	H77, D121, S215	GENBANK:XP_003803814
MER0368161	Otolemur garnettii	272	42-265	H85, D129, S224	GENBANK:XP_003802049
MER0619071	Ovis aries	255	30-255	H73, D117, S211	GENBANK:XP_004018154
MER0619725	Ovis aries	250	25-250	H68, D112, S206	UNIPROT:W5NYB0
MER0619725	Ovis aries	250	25-250	H68, D112, S206	UNIPROT:W5NYB0
MER0367907	Pan paniscus	246	21-243	H64, D108, S202	GENBANK:XP_003809163
MER0053512	Pan troglodytes	182	21-181	H64, D108, S138	GENBANK:XP_001170331
MER0624307	Pan troglodytes	160	21-159	H64, D108, S116,	GENBANK:XP_003952504
MER0519458	Panthera tigris	263	34-257	H77, D121, S215	GENBANK:XP_007098128
MER0517002	Pantholops hodgsonii	283	51-276	H94, N138, S232	GENBANK:XP_005961486
MER0392178	Papio anubis	246	21-243	H64, D108, S202	UNIPROT:A0A096NXD4
MER0392178	Papio anubis	246	21-243	H64, D108, S202	UNIPROT:A0A096NXD4
MER0524701	Pelodiscus sinensis	258	30-252	H67, D111, S210	GENBANK:XP_006126645
MER0524708	Pelodiscus sinensis	262	22-252	H65, D109, S208	GENBANK:XP_006126780
MER0525109	Pelodiscus sinensis	257	30-254	H73, D116, S211	GENBANK:XP_006131910
MER0525236	Pelodiscus sinensis	529	2-230	H45, D89, S188	GENBANK:XP_006134402
MER0519845	Physeter catodon	261	25-250	H68, D112, S206	GENBANK:XP_007119745
MER0367767	Pongo abelii	246	21-243	H64, D108, S202	UNIPROT:H2NKX8
MER0367767	Pongo abelii	246	21-243	H64, D108, S202	UNIPROT:H2NKX8
MER0392130	Pteropus alecto	465	240-462	H283, D327, S421	UNIPROT:L5L1A1
MER0392130	Pteropus alecto	465	240-462	H283, D327, S421	UNIPROT:L5L1A1
MER0392281	Saimiri boliviensis	246	21-243	H64, D108, S202	GENBANK:XP_003924292
MER0597539	Sorex araneus	252	22-246	H65, D109, S204	GENBANK:XP_004609717
MER0162486	Sus scrofa	251	25-251	H68, D112, S207	GENBANK:NP_001137165
MER0607765	Sus scrofa	164	25-162	H68, D112, S120	GENBANK:XP_005666283
MER0399486	synthetic construct	246	21-246	H64, D108, S202	GENBANK:BAJ20456
MER0596455	Tarsius syrichta	250	21-246	H64, D108, S202	GENBANK:XP_008058504
MER0483456	Trichechus manatus	242	21-240	H64, D107, S201	GENBANK:XP_004376614
MER0489130	Trichechus manatus	245	28-241	H64, D108, S199	GENBANK:XP_004391221
MER0392276	Tupaia chinensis	251	21-242	H64, D108, S201	GENBANK:ELW69301
MER0598869	Tupaia chinensis	246	21-245	H64, D108, S202	GENBANK:XP_006144649
MER0598871	Tupaia chinensis	251	21-244	H64, D108, S201	UNIPROT:L9L6F0
MER0598871	Tupaia chinensis	251	21-244	H64, D108, S201	UNIPROT:L9L6F0
MER0616628	Vicugna pacos	232	7-232	H50, D94, S188	GENBANK:XP_006219745