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Inhibitors

Peptidase

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MEROPS SUBMISSIONS

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information

Sequence features for peptidase homologue M16.984: insulysin unit 3

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure

 

MERNUM Species Sequence length Peptidase unit Active site residues Metal ligands Source
MER0689581 Acanthisitta chloris 986 691-901 E78, G757, E149, S828 N754, H75, H79, I758, E156, K835 GENBANK:XP_009082009
MER0301189 Alligator sinensis 1003 708-918 E95, G774, E166, S845 H92, N771, H96, I775, K852, E173 GENBANK:XP_006029478
MER0686318 Apaloderma vittatum 805 503-713 G569, S640 N566, I570, K647 GENBANK:XP_009877803
MER0352223 Apis dorsata 360 59-270 C126, Q197 S123, T127, N204 GENBANK:XP_006610177
MER0687799 Aptenodytes forsteri 1056 761-971 E148, G827, E219, S898 H145, N824, H149, I828, E226, K905 GENBANK:XP_009276302
MER0686196 Aquila chrysaetos 907 612-822 missing, G678, E70, S749 N675, missing, I679, missing, K756, E77 GENBANK:XP_011574524
MER0686199 Aquila chrysaetos 450 155-365 G221, S292 N218, I222, K299 GENBANK:XP_011574528
MER0555524 Astatotilapia burtoni 1007 720-922 G778, S849 N775, I779, C856 GENBANK:XP_005933659
MER0684054 Atta cephalotes 1011 716-927 E104, C783, E175, K854 K780, H101, H105, T784, E182, D861 GENBANK:XP_012057716
MER0682425 Balearica regulorum 391 96-306 G162, S233 N159, I163, K240 GENBANK:XP_010302375
MER0679621 Bison bison 1019 724-934 G790, E111, S861, E182 N787, H108, I791, H112, E189, I868 GENBANK:XP_010840502
MER0079226 Bos taurus 1019 724-934 G790, S861 N787, I791, I868 UNIPROT:Q24K02
MER0678472 Buceros rhinoceros 986 691-901 E78, G757, E149, S828 H75, N754, H79, I758, E156, K835 GENBANK:XP_010144389
MER0677061 Camelus dromedarius 1019 724-934 G790, E111, E860, E182 H108, N787, H112, I791, E189, I868 GENBANK:XP_010972589
MER0470729 Canis lupus familiaris 150 111-150 missing, missing missing, missing, missing UNIPROT:E2JCD1
MER0470729 Canis lupus familiaris 150 111-150 missing, missing missing, missing, missing UNIPROT:E2JCD1
MER0555481 Capra hircus 978 683-893 G749, E70, E819, E141 N746, H67, I750, H71, E148, I827 GENBANK:XP_005698269
MER0675923 Cariama cristata 968 690-900 E77, G756, E148, S827 H74, N753, I757, H78, K834, E155 GENBANK:XP_009693895
MER0675196 Cerapachys biroi 1016 719-928 C785, E106, K856, E177 K782, H103, T786, H107, E184, D863 GENBANK:XP_011329458
MER0670833 Ceratosolen solmsi 1055 751-961 E139, C818, E210, K889 H136, V815, H140, T819, E217, E896 GENBANK:XP_011499186
MER0673174 Chaetura pelagica 1103 808-1018 E195, G874, E266, S945 H192, N871, H196, I875, E273, K952 GENBANK:XP_009998424
MER0672012 Charadrius vociferus 993 698-908 G764, E85, S835, E156 H82, N761, H86, I765, E163, K842 GENBANK:XP_009887090
MER0583224 Chinchilla lanigera 1020 725-935 E111, G791, E182, S862 H108, N788, H112, I792, E189, I869 GENBANK:XP_005385882
MER0671447 Colius striatus 494 199-409 G265, E335 N262, I266, K343 GENBANK:XP_010197954
MER0669989 Colobus angolensis 1019 724-934 E111, G790, E182, E860 N787, H108, I791, H112, I868, E189 GENBANK:XP_011803227
MER0669992 Colobus angolensis 1019 724-934 G790, S861 N787, I791, I868 GENBANK:XP_011803228
MER0669998 Colobus angolensis 464 169-379 G235, E305 N232, I236, I313 GENBANK:XP_011803230
MER0578811 Columba livia 978 683-893 G749, S820 N746, I750, K827 GENBANK:XP_005507021
MER0663277 Corvus cornix 1018 723-933 G789, E110, E859, E181 H107, N786, H111, I790, E188, K867 GENBANK:XP_010408756
MER0663383 Corvus cornix 978 683-893 G749, S820 N746, I750, K827 GENBANK:XP_010408762
MER0666178 Crassostrea gigas 1021 725-934 E111, S790, E182, D861 K787, H108, H112, I791, E189, N868 GENBANK:XP_011428405
MER0665219 Cuculus canorus 968 683-893 E70, G749, E141, S820 H67, N746, H71, I750, E148, K827 GENBANK:XP_009569049
MER0125219 Danio rerio 978 683-893 E70, G749, E141, S820 H67, N746, I750, H71, K827, E148 UNIPROT:A4QP10
MER0125219 Danio rerio 978 683-893 E70, G749, E141, S820 H67, N746, I750, H71, K827, E148 UNIPROT:A4QP10
MER0566448 Diaphorina citri 438 348-419 missing, E55, E126, S409 missing, H52, missing, H56, E133, A416 GENBANK:XP_008480316
MER0664217 Egretta garzetta 998 703-913 E90, G769, E161, E839 H87, N766, H91, I770, K847, E168 GENBANK:XP_009640221
MER0098719 Equus caballus 1212 917-1127 E304, G983, E375, S1054 N980, H301, I984, H305, I1061, E382 UNIPROT:F6ZM82
MER0098719 Equus caballus 1212 917-1127 E304, G983, E375, S1054 N980, H301, I984, H305, I1061, E382 UNIPROT:F6ZM82
MER0661667 Esox lucius 1005 710-920 G776, E846 N773, I777, K854 GENBANK:XP_010862165
MER0661670 Esox lucius 1015 720-930 G786, S857 N783, I787, K864 GENBANK:XP_010862163
MER0658650 Eurypyga helias 385 144-354 G210, S281 N207, I211, K288 GENBANK:XP_010151026
MER0658235 Fopius arisanus 1013 714-930 H100, C786, I171, E857 L97, K783, M101, T787, E864, H178 GENBANK:XP_011312074
MER0655264 Fukomys damarensis 1002 707-917 E94, G773, E165, S844 N770, H91, I774, H95, I851, E172 GENBANK:XP_010630400
MER0655111 Fulmarus glacialis 997 706-916 E93, G772, E164, S843 N769, H90, H94, I773, E171, K850 GENBANK:XP_009582856
MER0178869 Gallus gallus 948 697-863 E208, G719, E279, S790 H205, N716, I720, H209, K797, E286 UNIPROT:E1BTQ0
MER0178869 Gallus gallus 948 697-863 E208, G719, E279, S790 H205, N716, I720, H209, K797, E286 UNIPROT:E1BTQ0
MER0653490 Gavia stellata 981 690-900 E77, G756, E148, S827 H74, N753, H78, I757, E155, K834 GENBANK:XP_009814696
MER0652078 Haliaeetus albicilla 649 354-564 G420, E490 N417, I421, K498 GENBANK:XP_009914023
MER0651495 Haliaeetus leucocephalus 922 734-837 missing, E70, E141, S764 missing, H67, missing, H71, K771, E148 GENBANK:XP_010563220
MER0651496 Haliaeetus leucocephalus 907 612-822 missing, G678, E70, S749 missing, N675, missing, I679, E77, K756 GENBANK:XP_010563221
MER0651499 Haliaeetus leucocephalus 825 530-740 missing, G596, missing, S667 N593, missing, missing, I597, missing, K674 GENBANK:XP_010563222
MER0651502 Haliaeetus leucocephalus 450 155-365 G221, S292 N218, I222, K299 GENBANK:XP_010563225
MER0651504 Haliaeetus leucocephalus 965 683-893 E70, G749, E141, E819 H67, N746, H71, I750, E148, K827 GENBANK:XP_010563219
MER0078753 Homo sapiens 1019 724-934 G790, E111, S861, E182 N787, H108, I791, H112, E189, I868 GENBANK:XP_016871679
MER0078753 Homo sapiens 1019 724-934 G790, E111, S861, E182 N787, H108, I791, H112, E189, I868 GENBANK:XP_016871679
MER0078753 Homo sapiens 1019 724-934 G790, E111, S861, E182 N787, H108, I791, H112, E189, I868 GENBANK:XP_016871679
MER0078753 Homo sapiens 1019 724-934 G790, E111, S861, E182 N787, H108, I791, H112, E189, I868 GENBANK:XP_016871679
MER0078753 Homo sapiens 1019 724-934 G790, E111, S861, E182 N787, H108, I791, H112, E189, I868 GENBANK:XP_016871679
MER0078753 Homo sapiens 1019 724-934 G790, E111, S861, E182 N787, H108, I791, H112, E189, I868 GENBANK:XP_016871679
MER0612472 Ictidomys tridecemlineatus 1019 724-934 E111, G790, E182, S861 H108, N787, H112, I791, E189, I868 GENBANK:XP_005333788
MER0648913 Larimichthys crocea 1015 720-930 E107, G786, E178, S857 N783, H104, I787, H108, C864, E185 GENBANK:XP_010732888
MER0647879 Linepithema humile 1022 721-932 E108, C788, E179, K859 H105, K785, T789, H109, D866, E186 GENBANK:XP_012215276
MER0647882 Linepithema humile 1017 716-927 C783, K854 K780, T784, D861 GENBANK:XP_012215277
MER0470214 Macaca fascicularis 543 248-458 G314, S385 N311, I315, I392 UNIPROT:G7PDK1
MER0470214 Macaca fascicularis 543 248-458 G314, S385 N311, I315, I392 UNIPROT:G7PDK1
MER0646499 Manacus vitellinus 999 704-914 G770, E91, S841, E162 N767, H88, I771, H92, E169, K848 GENBANK:XP_008928133
MER0645828 Mandrillus leucophaeus 1019 724-934 E111, G790, E182, S861 N787, H108, I791, H112, I868, E189 GENBANK:XP_011843871
MER0645837 Mandrillus leucophaeus 464 169-379 G235, S306 N232, I236, I313 GENBANK:XP_011843873
MER0543600 Maylandia zebra 150 1-65 missing, missing missing, missing, missing GENBANK:XP_004554600
MER0540629 Melopsittacus undulatus 978 683-893 G749, S820 N746, I750, K827 GENBANK:XP_005144112
MER0644519 Merops nubicus 794 503-713 G569, S640 N566, I570, K647 GENBANK:XP_008938615
MER0643882 Mesitornis unicolor 970 691-901 E78, G757, E149, S828 H75, N754, I758, H79, K835, E156 GENBANK:XP_010189995
MER0641315 Nannospalax galili 1019 724-934 G790, E111, S861, E182 N787, H108, I791, H112, E189, L868 GENBANK:XP_008847842
MER0638690 Nestor notabilis 986 691-901 E78, G757, E149, E827 H75, N754, H79, I758, E156, K835 GENBANK:XP_010010062
MER0635818 Nipponia nippon 989 694-904 G760, E81, S831, E152 H78, N757, H82, I761, E159, K838 GENBANK:XP_009464668
MER0470577 Nomascus leucogenys 464 169-379 G235, S306 N232, I236, I313 GENBANK:XP_003255271
MER0633904 Opisthocomus hoazin 1000 706-916 E93, G772, E164, S843 H90, N769, I773, H94, K850, E171 GENBANK:XP_009934009
MER0583764 Oreochromis niloticus 173 5-164 G20, S91 N17, I21, C98 GENBANK:XP_003460553
MER0097706 Ornithorhynchus anatinus 1301 1006-1216 E393, G1072, E464, S1143 N1069, H390, H394, I1073, E471, I1150 GENBANK:XP_001506502
MER0168041 Pan troglodytes 1019 724-934 E111, G790, E182, S861 H108, N787, H112, I791, E189, I868 UNIPROT:H2R7K5
MER0168041 Pan troglodytes 1019 724-934 E111, G790, E182, S861 H108, N787, H112, I791, E189, I868 UNIPROT:H2R7K5
MER0470576 Pan troglodytes 464 169-379 G235, S306 N232, I236, I313 GENBANK:XP_003312728
MER0633240 Pelecanus crispus 1035 733-943 G799, E120, E869, E191 N796, H117, I800, H121, E198, K877 GENBANK:XP_009484863
MER0497089 Phaethon lepturus 298 18-228 G84, S155 N81, I85, K162 GENBANK:XP_010281840
MER0631256 Phalacrocorax carbo 363 146-356 G212, S283 N209, I213, K290 GENBANK:XP_009506156
MER0629561 Picoides pubescens 1006 726-936 E113, G792, E184, E862 N789, H110, I793, H114, K870, E191 GENBANK:XP_009896096
MER0616809 Pogonomyrmex barbatus 1011 714-926 F106, C781, I177, K853 K778, H103, L107, T782, N184, D860 GENBANK:XP_011634998
MER0588915 Pterocles gutturalis 340 59-269 G125, S196 N122, I126, K203 GENBANK:XP_010082766
MER0438913 Python bivittatus 189 1-104 missing, S31 missing, missing, K38 GENBANK:XP_007444761
MER0124719 Rattus norvegicus 1019 500-934 G790, H112, S861, V183 N787, F109, I791, M113, H190, I868 PIR:S29509
MER0124719 Rattus norvegicus 1019 500-934 G790, H112, S861, V183 N787, F109, I791, M113, H190, I868 PIR:S29509
MER0562469 Rhinopithecus roxellana 1019 724-934 E111, G790, E182, S861 N787, H108, H112, I791, E189, I868 GENBANK:XP_010379622
MER0562498 Rhinopithecus roxellana 1019 724-934 G790, E860 N787, I791, I868 GENBANK:XP_010379621
MER0542472 Serinus canaria 978 683-893 E70, G749, E141, E819 N746, H67, I750, H71, K827, E148 GENBANK:XP_009085529
MER0528259 Solenopsis invicta 493 198-409 C265, K336 K262, T266, D343 GENBANK:XP_011172985
MER1116531 Strigamia maritima 1026 723-933 E110, C789, E181, R860 H107, R786, H111, V790, L867, E188 GENBANK:-
MER0522302 Struthio camelus 954 683-893 G749, E70, S820, E141 N746, H67, I750, H71, E148, K827 GENBANK:XP_009676076
MER0522315 Struthio camelus 494 199-409 G265, S336 N262, I266, K343 GENBANK:XP_009676079
MER0178311 Sus scrofa 1009 714-924 G780, E101, S851, E172 N777, H98, I781, H102, E179, V858 GENBANK:XP_001925416
MER0470579 Sus scrofa 464 169-379 G235, S306 N232, I236, V313 GENBANK:XP_003359343
MER0595738 Tarsius syrichta 1022 727-937 H115, G793, V186, S864 N790, F112, I794, M116, I871, H193 GENBANK:XP_008061852
MER0374908 Tauraco erythrolophus 958 683-893 G749, E70, S820, E141 H67, N746, H71, I750, E148, K827 GENBANK:XP_009986141
MER0388381 Tinamus guttatus 976 759-969 E146, G825, E217, S896 H143, N822, H147, I826, E224, K903 GENBANK:XP_010211466
MER1148894 Trichinella spiralis 1179 886-1096 T731, A952, V802, E1023 P949, E728, P732, I953, D809, S1030 GENBANK:XP_003376196
MER0597949 Tupaia chinensis 978 683-893 H71, G749, V142, S820 F68, N746, M72, I750, I827, H149 GENBANK:XP_006147699
MER0271250 Ursus maritimus 978 683-893 E70, G749, E141, S820 N746, H67, I750, H71, I827, E148 GENBANK:XP_008694470
MER0346506 Vollenhovia emeryi 1018 723-934 E111, C790, E182, K861 H108, K787, H112, T791, E189, D868 GENBANK:XP_011877956
MER0392099 Wasmannia auropunctata 1016 721-932 C788, E109, R859, E180 K785, H106, T789, H110, E187, D866 GENBANK:XP_011707871

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