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Literature for peptidase T02.001: glycosylasparaginase precursor

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, M Mutation, K Knockout, V Review, U Therapeutic. To select only the references relevant to a single topic, click the link above. See explanation.)

    2019
  1. Pande,S. and Guo,H.C.
    The T99K variant of glycosylasparaginase shows a new structural mechanism of the genetic disease aspartylglucosaminuria
    Protein Sci28, 1013-1023. PubMed  Europe PubMed DOI  M  S
    2. 2018
  2. Pande,S., Bizilj,W. and Guo,H.C.
    Biochemical and structural insights into an allelic variant causing the lysosomal storage disorder - aspartylglucosaminuria
    FEBS Lett592, 2550-2561. PubMed  Europe PubMed DOI  M
    3. 2017
  3. Pande,S., Lakshminarasimhan,D. and Guo,H.C.
    Crystal structure of a mutant glycosylasparaginase shedding light on aspartylglycosaminuria-causing mechanism as well as on hydrolysis of non-chitobiose substrate
    Mol Genet Metab121, 150-156. PubMed  Europe PubMed DOI  M  S
    4. 2016
  4. Arvio,M. and Mononen,I.
    Aspartylglycosaminuria: a review
    Orphanet J Rare Dis11, 162-162. PubMed  Europe PubMed DOI  M
    5. 2014
  5. Sui,L., Lakshminarasimhan,D., Pande,S. and Guo,H.C.
    Structural basis of a point mutation that causes the genetic disease aspartylglucosaminuria
    Structure22, 1855-1861. PubMed  Europe PubMed DOI  M  S
    6. 2012
  6. Aronson,N.N., Jr.
    Glycosylasparaginase precursor and other self-processing N-terminal nucleophile amidohydrolases
    [ISSN:978-0-12-407742-3]3, 3701-3705. DOI
    7. 2010
  7. Wang,Y. and Guo,H.C.
    Crystallographic snapshot of glycosylasparaginase precursor poised for autoprocessing
    J Mol Biol403, 120-130. PubMed  Europe PubMed DOI  S
    8. 2009
  8. Kelo,E., Noronkoski,T. and Mononen,I.
    Depletion of L-asparagine supply and apoptosis of leukemia cells induced by human glycosylasparaginase
    Leukemia23, 1167-1171. PubMed  Europe PubMed DOI  U
    9. 2008
  9. Michalska,K., Hernandez-Santoyo,A. and Jaskolski,M.
    The mechanism of autocatalytic activation of plant-type L-asparaginases
    J Biol Chem283, 13388-13397. PubMed  Europe PubMed DOI
    10. 2004
  10. Aronson,N.N., Jr.
    Glycosylasparaginase precursor and other self-processing N-terminal nucleophile amidohydrolases
    [ISSN:0-12-079610-4]2, 2086-2089.  V
  11. Gary,J.D. and Clarke,S.
    IadA beta-aspartyl dipeptidase
    [ISSN:0-12-079610-4]2, 972-977.  V
  12. [YEAR:1-3-2004]Saarela,J., Oinonen,C., Jalanko,A., Rouvinen,J. and Peltonen,L.
    Autoproteolytic activation of human aspartylglucosaminidase
    Biochem J378, 363-371. PubMed  Europe PubMed DOI  S
    13. 2003
  13. Qian,X., Guan,C. and Guo,H.C.
    A dual role for an aspartic acid in glycosylasparaginase autoproteolysis
    Structure11, 997-1003. PubMed  Europe PubMed DOI  S
  14. [YEAR:31-1-2003]Wang,Y. and Guo,H.C.
    Two-step dimerization for autoproteolysis to activate glycosylasparaginase
    J Biol Chem278, 3210-3219. PubMed  Europe PubMed DOI
    15. 2001
  15. [YEAR:15-7-2001]Risley,J.M., Huang,D.H., Kaylor,J.J., Malik,J.J., Xia,Y.Q. and York,W.M.
    Glycosylasparaginase activity requires the alpha-carboxyl group, but not the alpha-amino group, on N(4)-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)-L-asparagine
    Arch Biochem Biophys391, 165-170. PubMed  Europe PubMed DOI
  16. [YEAR:15-4-2001]Saarela,J., Laine,M., Oinonen,C., von Schantz,C., Jalanko,A., Rouvinen,J. and Peltonen,L.
    Molecular pathogenesis of a disease: structural consequences of aspartylglucosaminuria mutations
    Hum Mol Genet10, 983-995. PubMed  Europe PubMed
    17. 1999
  17. [YEAR:8-10-1999]Aronson,N.N., Jr.
    Aspartylglycosaminuria: biochemistry and molecular biology
    Biochim Biophys Acta1455, 139-154. PubMed  Europe PubMed DOI  V
  18. [YEAR:3-9-1999]Xu,Q., Buckley,D., Guan,C. and Guo,H.C.
    Structural insights into the mechanism of intramolecular proteolysis
    Cell98, 651-661. PubMed  Europe PubMed DOI  S
    19. 1998
  19. [YEAR:17-4-1998]Guan,C., Liu,Y., Shao,Y., Cui,T., Liao,W., Ewel,A., Whitaker,R. and Paulus,H.
    Characterization and functional analysis of the cis-autoproteolysis active center of glycosylasparaginase
    J Biol Chem273, 9695-9702. PubMed  Europe PubMed DOI
  20. [YEAR:7-8-1998]Guo,H.C., Xu,Q., Buckley,D. and Guan,C.
    Crystal structures of Flavobacterium glycosylasparaginase. An N-terminal nucleophile hydrolase activated by intramolecular proteolysis
    J Biol Chem273, 20205-20212. PubMed  Europe PubMed DOI  K  S
  21. Kaartinen,V., Mononen,I., Gonzalez-Gomez,I., Noronkoski,T., Heisterkamp,N. and Groffen,J.
    Phenotypic characterization of mice with targeted disruption of glycosylasparaginase gene: a mouse model for aspartylglycosaminuria
    J Inherit Metab Dis21, 207-209. PubMed  Europe PubMed DOI  K
  22. Xuan,J., Tarentino,A.L., Grimwood,B.G., Plummer,T.H., Jr., Cui,T., Guan,C. and Van Roey,P.
    Crystal structure of glycosylasparaginase from Flavobacterium meningosepticum
    Protein Sci7, 774-781. PubMed  Europe PubMed DOI  S
    23. 1996
  23. Aronson,N.N., Jr.
    Lysosomal glycosylasparaginase: a member of a family of amidases that employ a processed N-terminal threonine, serine or cysteine as a combined base-nucleophile catalyst
    Glycobiology6, 669-675. PubMed  Europe PubMed
  24. [YEAR:19-1-1996]Guan,C., Cui,T., Rao,V., Liao,W., Benner,J., Lin,C.L. and Comb,D.
    Activation of glycosylasparaginase. Formation of active N-terminal threonine by intramolecular autoproteolysis
    J Biol Chem271, 1732-1737. PubMed  Europe PubMed
  25. Liu,Y., Dunn,G.S. and Aronson,N.N., Jr.
    Purification, biochemistry and molecular cloning of an insect glycosylasparaginase from Spodoptera frugiperda
    Glycobiology6, 527-536. PubMed  Europe PubMed
  26. Tikkanen,R., Riikonen,A., Oinonen,C., Rouvinen,R. and Peltonen,L.
    Functional analyses of active site residues of human lysosomal aspartylglucosaminidase: implications for catalytic mechanism and autocatalytic activation
    EMBO J15, 2954-2960. PubMed  Europe PubMed
    27. 1995
  27. Oinonen,C., Tikkanen,R., Rouvinen,J. and Peltonen,L.
    Three-dimensional structure of human lysosomal aspartylglucosaminidase
    Nat Struct Biol2, 1102-1108. PubMed  Europe PubMed  S
    28. 1993
  28. Mononen,I., Fisher,K.J., Kaartinen,V. and Aronson,N.N., Jr.
    Aspartylglycosaminuria: protein chemistry and molecular biology of the most common lysosomal storage disorder of glycoprotein degradation
    FASEB J7, 1247-1256. PubMed  Europe PubMed
  29. [YEAR:30-11-1993]Tarentino,A.L. and Plummer,T.H., Jr.
    The first demonstration of a procaryotic glycosylasparaginase
    Biochem Biophys Res Commun197, 179-186. PubMed  Europe PubMed DOI
    30. 1991
  30. Kaartinen,V., Williams,J.C., Tomich,J., Yates,J.R., III, Hood,L.E. and Mononen,I.
    Glycosasparaginase from human leukocytes. Inactivation and covalent modification with diazo-oxonorvaline
    J Biol Chem266, 5860-5869. PubMed  Europe PubMed
    31. 1969
  31. Tarentino,A.L. and Maley,F.
    The purification and properties of a beta-aspartyl N-acetylglucosylamine amidohydrolase from hen oviduct
    Arch Biochem Biophys130, 295-303. PubMed  Europe PubMed

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