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Literature for peptidase T02.001: glycosylasparaginase precursor

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, M Mutation, K Knockout, V Review, U Therapeutic. To select only the references relevant to a single topic, click the link above. See explanation.)

    2019
  1. Pande,S. and Guo,H.C.<br>The T99K variant of glycosylasparaginase shows a new structural mechanism of the genetic disease aspartylglucosaminuria<br>Protein Sci (2019) 28, 1013-1023. PubMed  Europe PubMed DOI  M  S
    2. 2018
  2. Pande,S., Bizilj,W. and Guo,H.C.<br>Biochemical and structural insights into an allelic variant causing the lysosomal storage disorder - aspartylglucosaminuria<br>FEBS Lett (2018) 592, 2550-2561. PubMed  Europe PubMed DOI  M
    3. 2017
  3. Pande,S., Lakshminarasimhan,D. and Guo,H.C.<br>Crystal structure of a mutant glycosylasparaginase shedding light on aspartylglycosaminuria-causing mechanism as well as on hydrolysis of non-chitobiose substrate<br>Mol Genet Metab (2017) 121, 150-156. PubMed  Europe PubMed DOI  M  S
    4. 2016
  4. Arvio,M. and Mononen,I.<br>Aspartylglycosaminuria: a review<br>Orphanet J Rare Dis (2016) 11, 162-162. PubMed  Europe PubMed DOI  PMC  EPMC  M
    5. 2014
  5. Sui,L., Lakshminarasimhan,D., Pande,S. and Guo,H.C.<br>Structural basis of a point mutation that causes the genetic disease aspartylglucosaminuria<br>Structure (2014) 22, 1855-1861. PubMed  Europe PubMed DOI  M  S
    6. 2012
  6. Aronson,N.N., Jr.<br>Glycosylasparaginase precursor and other self-processing N-terminal nucleophile amidohydrolases<br>[ISSN:978-0-12-407742-3] (2012) 3, 3701-3705. DOI
    7. 2010
  7. Wang,Y. and Guo,H.C.<br>Crystallographic snapshot of glycosylasparaginase precursor poised for autoprocessing<br>J Mol Biol (2010) 403, 120-130. PubMed  Europe PubMed DOI  S
    8. 2009
  8. Kelo,E., Noronkoski,T. and Mononen,I.<br>Depletion of L-asparagine supply and apoptosis of leukemia cells induced by human glycosylasparaginase<br>Leukemia (2009) 23, 1167-1171. PubMed  Europe PubMed DOI  U
    9. 2008
  9. Michalska,K., Hernandez-Santoyo,A. and Jaskolski,M.<br>The mechanism of autocatalytic activation of plant-type L-asparaginases<br>J Biol Chem (2008) 283, 13388-13397. PubMed  Europe PubMed DOI
    10. 2004
  10. Aronson,N.N., Jr.<br>Glycosylasparaginase precursor and other self-processing N-terminal nucleophile amidohydrolases<br>[ISSN:0-12-079610-4] (2004) 2, 2086-2089.  V
  11. Gary,J.D. and Clarke,S.<br>IadA beta-aspartyl dipeptidase<br>[ISSN:0-12-079610-4] (2004) 2, 972-977.  V
  12. [YEAR:1-3-2004]Saarela,J., Oinonen,C., Jalanko,A., Rouvinen,J. and Peltonen,L.<br>Autoproteolytic activation of human aspartylglucosaminidase<br>Biochem J (1-3-2004) 378, 363-371. PubMed  Europe PubMed DOI  PMC  EPMC  S
    13. 2003
  13. Qian,X., Guan,C. and Guo,H.C.<br>A dual role for an aspartic acid in glycosylasparaginase autoproteolysis<br>Structure (2003) 11, 997-1003. PubMed  Europe PubMed DOI  S
  14. [YEAR:31-1-2003]Wang,Y. and Guo,H.C.<br>Two-step dimerization for autoproteolysis to activate glycosylasparaginase<br>J Biol Chem (31-1-2003) 278, 3210-3219. PubMed  Europe PubMed DOI
    15. 2001
  15. [YEAR:15-7-2001]Risley,J.M., Huang,D.H., Kaylor,J.J., Malik,J.J., Xia,Y.Q. and York,W.M.<br>Glycosylasparaginase activity requires the alpha-carboxyl group, but not the alpha-amino group, on N(4)-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)-L-asparagine<br>Arch Biochem Biophys (15-7-2001) 391, 165-170. PubMed  Europe PubMed DOI
  16. [YEAR:15-4-2001]Saarela,J., Laine,M., Oinonen,C., von Schantz,C., Jalanko,A., Rouvinen,J. and Peltonen,L.<br>Molecular pathogenesis of a disease: structural consequences of aspartylglucosaminuria mutations<br>Hum Mol Genet (15-4-2001) 10, 983-995. PubMed  Europe PubMed
    17. 1999
  17. [YEAR:8-10-1999]Aronson,N.N., Jr.<br>Aspartylglycosaminuria: biochemistry and molecular biology<br>Biochim Biophys Acta (8-10-1999) 1455, 139-154. PubMed  Europe PubMed DOI  V
  18. [YEAR:3-9-1999]Xu,Q., Buckley,D., Guan,C. and Guo,H.C.<br>Structural insights into the mechanism of intramolecular proteolysis<br>Cell (3-9-1999) 98, 651-661. PubMed  Europe PubMed DOI  S
    19. 1998
  19. [YEAR:17-4-1998]Guan,C., Liu,Y., Shao,Y., Cui,T., Liao,W., Ewel,A., Whitaker,R. and Paulus,H.<br>Characterization and functional analysis of the cis-autoproteolysis active center of glycosylasparaginase<br>J Biol Chem (17-4-1998) 273, 9695-9702. PubMed  Europe PubMed DOI
  20. [YEAR:7-8-1998]Guo,H.C., Xu,Q., Buckley,D. and Guan,C.<br>Crystal structures of Flavobacterium glycosylasparaginase. An N-terminal nucleophile hydrolase activated by intramolecular proteolysis<br>J Biol Chem (7-8-1998) 273, 20205-20212. PubMed  Europe PubMed DOI  K  S
  21. Kaartinen,V., Mononen,I., Gonzalez-Gomez,I., Noronkoski,T., Heisterkamp,N. and Groffen,J.<br>Phenotypic characterization of mice with targeted disruption of glycosylasparaginase gene: a mouse model for aspartylglycosaminuria<br>J Inherit Metab Dis (1998) 21, 207-209. PubMed  Europe PubMed DOI  K
  22. Xuan,J., Tarentino,A.L., Grimwood,B.G., Plummer,T.H., Jr., Cui,T., Guan,C. and Van Roey,P.<br>Crystal structure of glycosylasparaginase from Flavobacterium meningosepticum<br>Protein Sci (1998) 7, 774-781. PubMed  Europe PubMed DOI  PMC  EPMC  S
    23. 1996
  23. Aronson,N.N., Jr.<br>Lysosomal glycosylasparaginase: a member of a family of amidases that employ a processed N-terminal threonine, serine or cysteine as a combined base-nucleophile catalyst<br>Glycobiology (1996) 6, 669-675. PubMed  Europe PubMed
  24. [YEAR:19-1-1996]Guan,C., Cui,T., Rao,V., Liao,W., Benner,J., Lin,C.L. and Comb,D.<br>Activation of glycosylasparaginase. Formation of active N-terminal threonine by intramolecular autoproteolysis<br>J Biol Chem (19-1-1996) 271, 1732-1737. PubMed  Europe PubMed
  25. Liu,Y., Dunn,G.S. and Aronson,N.N., Jr.<br>Purification, biochemistry and molecular cloning of an insect glycosylasparaginase from Spodoptera frugiperda<br>Glycobiology (1996) 6, 527-536. PubMed  Europe PubMed
  26. Tikkanen,R., Riikonen,A., Oinonen,C., Rouvinen,R. and Peltonen,L.<br>Functional analyses of active site residues of human lysosomal aspartylglucosaminidase: implications for catalytic mechanism and autocatalytic activation<br>EMBO J (1996) 15, 2954-2960. PubMed  Europe PubMed  PMC  EPMC
    27. 1995
  27. Oinonen,C., Tikkanen,R., Rouvinen,J. and Peltonen,L.<br>Three-dimensional structure of human lysosomal aspartylglucosaminidase<br>Nat Struct Biol (1995) 2, 1102-1108. PubMed  Europe PubMed  S
    28. 1993
  28. Mononen,I., Fisher,K.J., Kaartinen,V. and Aronson,N.N., Jr.<br>Aspartylglycosaminuria: protein chemistry and molecular biology of the most common lysosomal storage disorder of glycoprotein degradation<br>FASEB J (1993) 7, 1247-1256. PubMed  Europe PubMed
  29. [YEAR:30-11-1993]Tarentino,A.L. and Plummer,T.H., Jr.<br>The first demonstration of a procaryotic glycosylasparaginase<br>Biochem Biophys Res Commun (30-11-1993) 197, 179-186. PubMed  Europe PubMed DOI
    30. 1991
  30. Kaartinen,V., Williams,J.C., Tomich,J., Yates,J.R., III, Hood,L.E. and Mononen,I.<br>Glycosasparaginase from human leukocytes. Inactivation and covalent modification with diazo-oxonorvaline<br>J Biol Chem (1991) 266, 5860-5869. PubMed  Europe PubMed
    31. 1969
  31. Tarentino,A.L. and Maley,F.<br>The purification and properties of a beta-aspartyl N-acetylglucosylamine amidohydrolase from hen oviduct<br>Arch Biochem Biophys (1969) 130, 295-303. PubMed  Europe PubMed

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