$VAR1 = undef;
Summary for peptidase T02.001: glycosylasparaginase precursor
| Names | |
|---|---|
| MEROPS Name | glycosylasparaginase precursor |
| Other names | aspartylglucosaminidase precursor, glycoasparaginase precursor |
| Domain architecture |
|---|
| MEROPS Classification | |
|---|---|
| Classification | Clan PB >> Subclan PB(T) >> Family T2 >> Subfamily (none) >> T02.001 |
| Holotype | glycosylasparaginase precursor (Homo sapiens), Uniprot accession P20933 (peptidase unit: 206-346), MERNUM MER0003299 |
| History | Identifier created: MEROPS 3.4 (5 November 1999) |
| Activity | |||
|---|---|---|---|
| Catalytic type | Threonine | ||
| NC-IUBMB | Not yet included in IUBMB recommendations. | ||
| Activity status | human: active (Aronson, 2004) mouse: active (Kaartinen et al., 1998) | ||
| Knockout | A deficiency of glycosylasparaginase results in the human genetic disorder known as aspartylglycosaminuria (Oinonen et al., 1995). Mice with targeted disruption of the glycosylasparaginase gene may form a model for the human disease (Kaartinen et al., 1998). | ||
| Pathways | KEGG | Other glycan degradation | |
| Other databases | TREEFAM | http://www.treefam.org/family/TF300756 | |
| Human genetics | ||||||
|---|---|---|---|---|---|---|
| Gene symbol | Locus | Megabases | Ensembl | Entrez gene | Gene Cards | OMIM |
| AGA | 4q23-q27 | ENSG00000038002 | 175 | AGA | 208400 | |
| Mouse genetics | ||||||
| Gene symbol | Position | Megabases | Ensembl | Entrez gene | MGI | |
| Aga | 8:B3 | ENSMUSG00000031521 | 11593 | MGI:104873 | ||
