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Literature for peptidase S28.002: dipeptidyl-peptidase II

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: S Structure, P Specificity, K Knockout, I Inhibitor, L Localization, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2022
  1. Benramdane,S., De Loose,J., Beyens,O., Van Rymenant,Y., Vliegen,G., Augustyns,K., De Winter,H., De Meester,I. and Van der Veken,P.
    Vildagliptin-Derived Dipeptidyl Peptidase 9 (DPP9) Inhibitors: Identification of a DPP8/9-Specific Lead
    ChemMedChem17, e202200097-e202200097. PubMed  Europe PubMed DOI  I
    2. 2019
  2. Kong,F., Pang,X., Zhao,J., Deng,P., Zheng,M., Zhong,D. and Chen,X.
    Hydrolytic metabolism of cyanopyrrolidine DPP-4 inhibitors mediated by dipeptidyl peptidases
    Drug Metab Dispos47, 238-248. PubMed  Europe PubMed DOI  I
    3. 2017
  3. Sato,A. and Ogita,H.
    Pathophysiological implications of dipeptidyl peptidases
    Curr Protein Pept Sci18, 843-849. PubMed  Europe PubMed DOI
    4. 2016
  4. Gandhi,D., Chanalia,P., Attri,P. and Dhanda,S.
    Dipeptidyl peptidase-II from probiotic Pediococcus acidilactici: purification and functional characterization
    Int J Biol Macromol93, 919-932. PubMed  Europe PubMed DOI
    5. 2015
  5. Khaket,T.P., Dhanda,S., Jodha,D. and Singh,J.
    Purification and biochemical characterization of dipeptidyl peptidase-II (DPP7) homologue from germinated Vigna radiata seeds
    Bioorg Chem63, 132-141. PubMed  Europe PubMed DOI
    6. 2012
  6. Bezerra,G.A., Dobrovetsky,E., Dong,A., Seitova,A., Crombett,L., Shewchuk,L.M., Hassell,A.M., Sweitzer,S.M., Sweitzer,T.D., McDevitt,P.J., Johanson,K.O., Kennedy-Wilson,K.M., Cossar,D., Bochkarev,A., Gruber,K. and Dhe-Paganon,S.
    Structures of human DPP7 reveal the molecular basis of specific inhibition and the architectural diversity of proline-specific peptidases
    PLoS ONE7, e43019-e43019. PubMed  Europe PubMed DOI  S  I
  7. De Meester,I.
    Dipeptidyl-peptidase II
    [ISSN:978-0-12-407742-3]3, 3432-3438. DOI
    8. 2011
  8. Chen,S.J. and Jiaang,W.T.
    Current advances and therapeutic potential of agents targeting dipeptidyl peptidases-IV, -II, 8/9 and fibroblast activation protein
    Curr Top Med Chem11, 1447-1463. PubMed  Europe PubMed DOI  I
  9. Mele,D.A., Sampson,J.F. and Huber,B.T.
    Th17 differentiation is the default program for DPP2-deficient T-cell differentiation
    Eur J Immunol41, 1583-1593. PubMed  Europe PubMed DOI  K
    10. 2010
  10. Danilov,A.V., Danilova,O.V., Brown,J.R., Rabinowitz,A., Klein,A.K. and Huber,B.T.
    Dipeptidyl peptidase 2 apoptosis assay determines the B-cell activation stage and predicts prognosis in chronic lymphocytic leukemia
    Exp Hematol38, 1167-1177. PubMed  Europe PubMed DOI  I
  11. Soisson,S.M., Patel,S.B., Abeywickrema,P.D., Bryne,N.J., Diehl,R.E., Hall,D.L., Ford,R.E., Reid,J.C., Rickert,K.W., Shipman,J.M., Sharma,S. and Lumb,K.J.
    Structural definition and substrate specificity of the S28 protease family: the crystal structure of human prolylcarboxypeptidase
    BMC Struct Biol10, 16-16. PubMed  Europe PubMed DOI  S
    12. 2009
  12. Danilova,O.V., Tai,A.K., Mele,D.A., Beinborn,M., Leiter,A.B., Greenberg,A.S., Perfield,J.W., Defuria,J., Singru,P.S., Lechan,R.M. and Huber,B.T.
    Neurogenin 3-specific dipeptidyl peptidase-2 deficiency causes impaired glucose tolerance, insulin resistance, and visceral obesity
    Endocrinology150, 5240-5248. PubMed  Europe PubMed DOI
  13. Hinds,P.W.
    Keeping quiet: a key role for dipeptidyl peptidase 2
    Cell Cycle8, 2683-2684. PubMed  Europe PubMed  V
  14. Mele,D.A., Bista,P., Baez,D.V. and Huber,B.T.
    Dipeptidyl peptidase 2 is an essential survival factor in the regulation of cell quiescence
    Cell Cycle8, 2425-2434. PubMed  Europe PubMed
    15. 2008
  15. Rasheed,A.M., Namala,R., Manne,N., Vanjivaka,S., Dhamjewar,R. and Balasubramanian,G.
    Concise and efficient synthesis of highly potent and selective dipeptidyl peptidase II inhibitors
    Synthetic Communications38, 162-169. DOI  I
  16. Sharoyan,S.G., Antonyan,A.A., Mardanyan,S.S., Lupidi,G., Cuccioloni,M., Angeletti,M. and Cristalli,G.
    Complex of dipeptidyl peptidase II with adenosine deaminase
    Biochemistry (Mosc)73, 943-949. PubMed  Europe PubMed DOI
    17. 2007
  17. Danilova,O., Li,B., Szardenings,A.K., Huber,B.T. and Rosenblum,J.S.
    Synthesis and activity of a potent, specific azabicyclo[3.3.0]-octane-based DPP II inhibitor
    Bioorg Med Chem Lett17, 507-510. PubMed  Europe PubMed DOI  I
  18. Van der Veken,P., Haemers,A. and Augustyns,K.
    Prolyl peptidases related to dipeptidyl peptidase IV: potential of specific inhibitors in drug discovery
    Curr Top Med Chem7, 621-635. PubMed  Europe PubMed DOI  V
    19. 2006
  19. Maes,M.B., Lambeir,A.M., Van der Veken,P., De Winter,B., Augustyns,K., Scharpe,S. and De Meester,I.
    In vivo effects of a potent, selective DPPII inhibitor: UAMC00039 is a possible tool for the elucidation of the physiological function of DPPII
    Adv Exp Med Biol575, 73-85. PubMed  Europe PubMed DOI  I
  20. [YEAR:25-4-2006]Maes,M.B., Martinet,W., Schrijvers,D.M., Van der Veken,P., De Meyer,G.R., Augustyns,K., Lambeir,A.M., Scharpe,S. and De Meester,I.
    Dipeptidyl peptidase II and leukocyte cell death
    Biochem Pharmacol72, 70-79. PubMed  Europe PubMed DOI  I
  21. [YEAR:14-7-2006]Soroka,A., Van der Veken,P., De Meester,I., Lambeir,A.M., Maes,M.B., Scharpe,S., Haemers,A. and Augustyns,K.
    Synthesis and dipeptidyl peptidase inhibition of N-(4-substituted-2,4-diaminobutanoyl)piperidines
    Bioorg Med Chem Lett16, 4777-4779. PubMed  Europe PubMed DOI  I
    22. 2005
  22. Danilov,A.V., Klein,A.K., Lee,H.J., Baez,D.V. and Huber,B.T.
    Differential control of G0 programme in chronic lymphocytic leukaemia: a novel prognostic factor
    Br J Haematol128, 472-481. PubMed  Europe PubMed DOI
  23. Hu,Y., Ma,L., Wu,M., Wong,M.S., Li,B., Corral,S., Yu,Z., Nomanbhoy,T., Alemayehu,S., Fuller,S.R., Rosenblum,J.S., Rozenkrants,N., Minimo,L.C., Ripka,W.C., Szardenings,A.K., Kozarich,J.W. and Shreder,K.R.
    Synthesis and structure-activity relationship of N-alkyl Gly-boro-Pro inhibitors of DPP4, FAP, and DPP7
    Bioorg Med Chem Lett15, 4239-4242. PubMed  Europe PubMed DOI  I
  24. Lankas,G.R., Leiting,B., Roy,R.S., Eiermann,G.J., Beconi,M.G., Biftu,T., Chan,C.C., Edmondson,S., Feeney,W.P., He,H., Ippolito,D.E., Kim,D., Lyons,K.A., Ok,H.O., Patel,R.A., Petrov,A.N., Pryor,K.A., Qian,X., Reigle,L., Woods,A., Wu,J.K., Zaller,D., Zhang,X., Zhu,L., Weber,A.E. and Thornberry,N.A.
    Dipeptidyl peptidase IV inhibition for the treatment of type 2 diabetes: potential importance of selectivity over dipeptidyl peptidases 8 and 9
    Diabetes54, 2988-2994. PubMed  Europe PubMed DOI  I
  25. [YEAR:18-11-2005]Maes,M.B., Lambeir,A.M., Gilany,K., Senten,K., Van der Veken,P., Leiting,B., Augustyns,K., Scharpe,S. and De Meester,I.
    Kinetic investigation of human dipeptidyl peptidase II (DPPII)-mediated hydrolysis of dipeptide derivatives and its identification as quiescent cell proline dipeptidase (QPP)/dipeptidyl peptidase 7 (DPP7)
    Biochem J386, 315-324. PubMed  Europe PubMed DOI
  26. Shreder,K.R., Wong,M.S., Corral,S., Yu,Z., Winn,D.T., Wu,M., Hu,Y., Nomanbhoy,T., Alemayehu,S., Fuller,S.R., Rosenblum,J.S. and Kozarich,J.W.
    Boro-norleucine as a P1 residue for the design of selective and potent DPP7 inhibitors
    Bioorg Med Chem Lett15, 4256-4260. PubMed  Europe PubMed DOI  I
  27. [YEAR:24-3-2005]Van der Veken,P., Senten,K., Kertesz,I., De Meester,I., Lambeir,A.M., Maes,M.B., Scharpe,S., Haemers,A. and Augustyns,K.
    Fluoro-olefins as peptidomimetic inhibitors of dipeptidyl peptidases
    J Med Chem48, 1768-1780. PubMed  Europe PubMed DOI  I
    28. 2004
  28. McDonald,J.K. and Ohkubo,I.
    Dipeptidyl-peptidase II
    [ISSN:0-12-079610-4]2, 1938-1943.  V
  29. [YEAR:20-5-2004]Senten,K., Van der Veken,P., De Meester,I., Lambeir,A.M., Scharpe,S., Haemers,A. and Augustyns,K.
    Gamma-amino-substituted analogues of 1-[(S)-2,4-diaminobutanoyl]piperidine as highly potent and selective dipeptidyl peptidase II inhibitors
    J Med Chem47, 2906-2916. PubMed  Europe PubMed DOI  I
    30. 2003
  30. [YEAR:15-4-2003]Leiting,B., Pryor,K.D., Wu,J.K., Marsilio,F., Patel,R.A., Craik,C.S., Ellman,J.A., Cummings,R.T. and Thornberry,N.A.
    Catalytic properties and inhibition of proline-specific dipeptidyl peptidases II, IV and VII
    Biochem J371, 525-532. PubMed  Europe PubMed DOI  P
  31. [YEAR:6-11-2003]Senten,K., Van der Veken,P., De Meester,I., Lambeir,A.M., Scharpe,S., Haemers,A. and Augustyns,K.
    Design, synthesis, and SAR of potent and selective dipeptide-derived inhibitors for dipeptidyl peptidases
    J Med Chem46, 5005-5014. PubMed  Europe PubMed DOI  I
    32. 2002
  32. [YEAR:21-10-2002]Senten,K., Van der Veken,P., Bal,G., De Meester,I., Lambeir,A.M., Scharpe,S., Bauvois,B., Haemers,A. and Augustyns,K.
    Development of potent and selective dipeptidyl peptidase II inhibitors
    Bioorg Med Chem Lett12, 2825-2828. PubMed  Europe PubMed DOI  I
    33. 2001
  33. Araki,H., Li,Y., Yamamoto,Y., Haneda,M., Nishi,K., Kikkawa,R. and Ohkubo,I.
    Purification, molecular cloning, and immunohistochemical localization of dipeptidyl peptidase II from the rat kidney and its identity with quiescent cell proline dipeptidase
    J Biochem129, 279-288. PubMed  Europe PubMed
  34. [YEAR:15-1-2001]Fukasawa,K.M., Fukasawa,K., Higaki,K., Shiina,N., Ohno,M., Ito,S., Otogoto,J. and Ota,N.
    Cloning and functional expression of rat kidney dipeptidyl peptidase II
    Biochem J353, 283-290. PubMed  Europe PubMed DOI
    35. 2000
  35. [YEAR:1-9-2000]Chiravuri,M., Lee,H., Mathieu,S.L. and Huber,B.T.
    Homodimerization via a leucine zipper motif is required for enzymatic activity of quiescent cell proline dipeptidase
    J Biol Chem275, 26994-26999. PubMed  Europe PubMed DOI
  36. [YEAR:15-11-2000]Chiravuri,M., Agarraberes,F., Mathieu,S.L., Lee,H. and Huber,B.T.
    Vesicular localization and characterization of a novel post-proline-cleaving aminodipeptidase, quiescent cell proline dipeptidase
    J Immunol165, 5695-5702. PubMed  Europe PubMed
  37. Dikov,A., Dimitrova,M., Pajpanova,T., Krieg,R. and Halbhuber,K.J.
    Histochemical method for dipeptidyl aminopeptidase II with a new anthraquinonyl hydrazide substrate
    Cell Mol Biol (Noisy-le-grand)46, 1213-1218. PubMed  Europe PubMed  L
  38. [YEAR:15-6-2000]Stockel-Maschek,A., Mrestani-Klaus,C., Stiebitz,B., Demuth,H. and Neubert,K.
    Thioxo amino acid pyrrolidides and thiazolidides: new inhibitors of proline specific peptidases
    Biochim Biophys Acta1479, 15-31. PubMed  Europe PubMed DOI  I
    39. 1999
  39. [YEAR:15-9-1999]Chiravuri,M., Schmitz,T., Yardley,K., Underwood,R., Dayal,Y. and Huber,B.T.
    A novel apoptotic pathway in quiescent lymphocytes identified by inhibition of a post-proline cleaving aminodipeptidase: A candidate target protease, quiescent cell proline dipeptidase
    J Immunol163, 3092-3099. PubMed  Europe PubMed
  40. [YEAR:26-11-1999]Underwood,R., Chiravuri,M., Lee,H., Schmitz,T., Kabcenell,A.K., Yardley,K. and Huber,B.T.
    Sequence, purification, and cloning of an intracellular serine protease, quiescent cell proline dipeptidase
    J Biol Chem274, 34053-34058. PubMed  Europe PubMed DOI
    41. 1998
  41. Akiyama,T., Sawa,R., Naganawa,H., Muraoka,Y., Aoyagi,T. and Takeuchi,T.
    Epostatin, new inhibitor of dipeptidyl peptidase II, produced by Streptomyces sp. MJ995-OF5 II. Structure elucidation
    J Antibiot (Tokyo)51, 372-373. PubMed  Europe PubMed  I
  42. Akiyama,T., Harada,S., Kojima,F., Kinoshita,N., Hamada,M., Muraoka,Y., Aoyagi,T. and Takeuchi,T.
    Epostatin, new inhibitor of dipeptidyl peptidase II, produced by Streptomyces sp. MJ995-OF5. I. Taxonomy of producing strain, fermentation, isolation, physico-chemical properties and biological properties
    J Antibiot (Tokyo)51, 253-260. PubMed  Europe PubMed  I
    43. 1996
  43. Dunn,A.D., Myers,H.E. and Dunn,J.T.
    The combined action of two thyroidal proteases releases T4 from the dominant hormone-forming site of thyroglobulin
    Endocrinology137, 3279-3285. PubMed  Europe PubMed DOI
  44. Huang,K., Takagaki,M., Kani,K. and Ohkubo,I.
    Dipeptidyl peptidase II from porcine seminal plasma: purification, characterization, and its homology to granzymes, cytotoxic cell proteinases (CCP 1-4)
    Biochim Biophys Acta1290, 149-156. PubMed  Europe PubMed DOI  I
  45. Rawlings,N.D. and Barrett,A.J.
    Dipeptidyl-peptidase II is related to lysosomal Pro-X carboxypeptidase
    Biochim Biophys Acta1298, 1-3. PubMed  Europe PubMed DOI
    46. 1995
  46. Struckhoff,G.
    Transforming growth factor beta1 and parathyroid hormone-related protein control the secretion of dipeptidyl peptidase II by rat astrocytes
    Neurosci Lett189, 117-120. PubMed  Europe PubMed DOI
    47. 1993
  47. [YEAR:20-8-1993]Struckhoff,G.
    Dipeptidyl peptidase II in astrocytes of the rat brain. Meningeal cells increase enzymic activity in cultivated astrocytes
    Brain Res620, 49-57. PubMed  Europe PubMed DOI
    48. 1988
  48. [YEAR:8-7-1988]Stevens,B.R., Fernandez,A., Sumners,C. and Hearing,L.
    Neonatal rat brain astroglial dipeptidyl peptidase II activity regulation by cations and anions
    Neurosci Lett89, 319-322. PubMed  Europe PubMed
    49. 1986
  49. McDonald,J.K. and Barrett,A.J.
    Mammalian Proteases: a Glossary and Bibliography. Volume 2: Exopeptidases
    [ISSN:ISBN 0-12-079502-7]
  50. [YEAR:15-5-1986]Struckhoff,G. and Heymann,E.
    Rat peritoneal mast cells release dipeptidyl peptidase II
    Biochem J236, 215-219. PubMed  Europe PubMed
    51. 1985
  51. [YEAR:15-5-1985]Nagatsu,T., Sakai,T., Kojima,K., Araki,E., Sakakibara,S., Fukasawa,K. and Harada,M.
    A sensitive and specific assay for dipeptidyl-aminopeptidase II in serum and tissues by liquid chromatography-fluorometry
    Anal Biochem147, 80-85. PubMed  Europe PubMed
    52. 1981
  52. Stauber,W.T. and Ong,S.H.
    Fluorescence demonstration of dipeptidyl peptidase II in skeletal, cardiac, and vascular smooth muscles
    J Histochem Cytochem29, 672-677. PubMed  Europe PubMed
    53. 1980
  53. [YEAR:6-11-1980]McDonald,J.K. and Schwabe,C.
    Dipeptidyl peptidase II of bovine dental pulp. Initial demonstration and characterization as a fibroblastic, lysosomal peptidase of the serine class active on collagen-related peptides
    Biochim Biophys Acta616, 68-81. PubMed  Europe PubMed  I
    54. 1979
  54. Smith,R.E. and Dean,P.N.
    A study of acid phosphatase and dipeptidyl aminopeptidase II in monodispersed anterior pituitary cells using flow cytometry and electron microscopy
    J Histochem Cytochem27, 1499-1504. PubMed  Europe PubMed
    55. 1977
  55. McDonald,J.K. and Schwabe,C.
    Intracellular exopeptidases
    311-391.
    56. 1969
  56. Hopsu-Havu,V.K. and Jansen,C.T.
    Peptidases in the skin. II. Demonstration and partial separation of several specific dipeptide naphthylamidases in the rat and human skin
    Arch Klin Exp Dermatol235, 53-62. PubMed  Europe PubMed DOI
    57. 1968
  57. McDonald,J.K., Reilly,T.J., Zeitman,B.B. and Ellis,S.
    Dipeptidyl arylamidase II of the pituitary. Properties of lysylalanyl-beta-naphthylamide hydrolysis: inhibition by cations, distribution in tissues, and subcellular localization
    J Biol Chem243, 2028-2037. PubMed  Europe PubMed  I
  58. [YEAR:10-8-1968]McDonald,J.K., Leibach,F.H., Grindeland,R.E. and Ellis,S.
    Purification of dipeptidyl aminopeptidase II (dipeptidyl arylamidase II) of the anterior pituitary gland. Peptidase and dipeptide esterase activities
    J Biol Chem243, 4143-4150. PubMed  Europe PubMed

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