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Literature for peptidase S28.002: dipeptidyl-peptidase II

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: S Structure, P Specificity, K Knockout, I Inhibitor, L Localization, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2022
  1. Benramdane,S., De Loose,J., Beyens,O., Van Rymenant,Y., Vliegen,G., Augustyns,K., De Winter,H., De Meester,I. and Van der Veken,P.<br>Vildagliptin-Derived Dipeptidyl Peptidase 9 (DPP9) Inhibitors: Identification of a DPP8/9-Specific Lead<br>ChemMedChem (2022) 17, e202200097-e202200097. PubMed  Europe PubMed DOI  I
    2. 2019
  2. Kong,F., Pang,X., Zhao,J., Deng,P., Zheng,M., Zhong,D. and Chen,X.<br>Hydrolytic metabolism of cyanopyrrolidine DPP-4 inhibitors mediated by dipeptidyl peptidases<br>Drug Metab Dispos (2019) 47, 238-248. PubMed  Europe PubMed DOI  I
    3. 2017
  3. Sato,A. and Ogita,H.<br>Pathophysiological implications of dipeptidyl peptidases<br>Curr Protein Pept Sci (2017) 18, 843-849. PubMed  Europe PubMed DOI
    4. 2016
  4. Gandhi,D., Chanalia,P., Attri,P. and Dhanda,S.<br>Dipeptidyl peptidase-II from probiotic Pediococcus acidilactici: purification and functional characterization<br>Int J Biol Macromol (2016) 93, 919-932. PubMed  Europe PubMed DOI
    5. 2015
  5. Khaket,T.P., Dhanda,S., Jodha,D. and Singh,J.<br>Purification and biochemical characterization of dipeptidyl peptidase-II (DPP7) homologue from germinated Vigna radiata seeds<br>Bioorg Chem (2015) 63, 132-141. PubMed  Europe PubMed DOI
    6. 2012
  6. Bezerra,G.A., Dobrovetsky,E., Dong,A., Seitova,A., Crombett,L., Shewchuk,L.M., Hassell,A.M., Sweitzer,S.M., Sweitzer,T.D., McDevitt,P.J., Johanson,K.O., Kennedy-Wilson,K.M., Cossar,D., Bochkarev,A., Gruber,K. and Dhe-Paganon,S.<br>Structures of human DPP7 reveal the molecular basis of specific inhibition and the architectural diversity of proline-specific peptidases<br>PLoS ONE (2012) 7, e43019-e43019. PubMed  Europe PubMed DOI  S  I
  7. De Meester,I.<br>Dipeptidyl-peptidase II<br>[ISSN:978-0-12-407742-3] (2012) 3, 3432-3438. DOI
    8. 2011
  8. Chen,S.J. and Jiaang,W.T.<br>Current advances and therapeutic potential of agents targeting dipeptidyl peptidases-IV, -II, 8/9 and fibroblast activation protein<br>Curr Top Med Chem (2011) 11, 1447-1463. PubMed  Europe PubMed DOI  I
  9. Mele,D.A., Sampson,J.F. and Huber,B.T.<br>Th17 differentiation is the default program for DPP2-deficient T-cell differentiation<br>Eur J Immunol (2011) 41, 1583-1593. PubMed  Europe PubMed DOI  K
    10. 2010
  10. Danilov,A.V., Danilova,O.V., Brown,J.R., Rabinowitz,A., Klein,A.K. and Huber,B.T.<br>Dipeptidyl peptidase 2 apoptosis assay determines the B-cell activation stage and predicts prognosis in chronic lymphocytic leukemia<br>Exp Hematol (2010) 38, 1167-1177. PubMed  Europe PubMed DOI  I
  11. Soisson,S.M., Patel,S.B., Abeywickrema,P.D., Bryne,N.J., Diehl,R.E., Hall,D.L., Ford,R.E., Reid,J.C., Rickert,K.W., Shipman,J.M., Sharma,S. and Lumb,K.J.<br>Structural definition and substrate specificity of the S28 protease family: the crystal structure of human prolylcarboxypeptidase<br>BMC Struct Biol (2010) 10, 16-16. PubMed  Europe PubMed DOI  S
    12. 2009
  12. Danilova,O.V., Tai,A.K., Mele,D.A., Beinborn,M., Leiter,A.B., Greenberg,A.S., Perfield,J.W., Defuria,J., Singru,P.S., Lechan,R.M. and Huber,B.T.<br>Neurogenin 3-specific dipeptidyl peptidase-2 deficiency causes impaired glucose tolerance, insulin resistance, and visceral obesity<br>Endocrinology (2009) 150, 5240-5248. PubMed  Europe PubMed DOI
  13. Hinds,P.W.<br>Keeping quiet: a key role for dipeptidyl peptidase 2<br>Cell Cycle (2009) 8, 2683-2684. PubMed  Europe PubMed  V
  14. Mele,D.A., Bista,P., Baez,D.V. and Huber,B.T.<br>Dipeptidyl peptidase 2 is an essential survival factor in the regulation of cell quiescence<br>Cell Cycle (2009) 8, 2425-2434. PubMed  Europe PubMed
    15. 2008
  15. Rasheed,A.M., Namala,R., Manne,N., Vanjivaka,S., Dhamjewar,R. and Balasubramanian,G.<br>Concise and efficient synthesis of highly potent and selective dipeptidyl peptidase II inhibitors<br>Synthetic Communications (2008) 38, 162-169. DOI  I
  16. Sharoyan,S.G., Antonyan,A.A., Mardanyan,S.S., Lupidi,G., Cuccioloni,M., Angeletti,M. and Cristalli,G.<br>Complex of dipeptidyl peptidase II with adenosine deaminase<br>Biochemistry (Mosc) (2008) 73, 943-949. PubMed  Europe PubMed DOI
    17. 2007
  17. Danilova,O., Li,B., Szardenings,A.K., Huber,B.T. and Rosenblum,J.S.<br>Synthesis and activity of a potent, specific azabicyclo[3.3.0]-octane-based DPP II inhibitor<br>Bioorg Med Chem Lett (2007) 17, 507-510. PubMed  Europe PubMed DOI  PMC  EPMC  I
  18. Van der Veken,P., Haemers,A. and Augustyns,K.<br>Prolyl peptidases related to dipeptidyl peptidase IV: potential of specific inhibitors in drug discovery<br>Curr Top Med Chem (2007) 7, 621-635. PubMed  Europe PubMed DOI  V
    19. 2006
  19. [YEAR:25-4-2006]Maes,M.B., Martinet,W., Schrijvers,D.M., Van der Veken,P., De Meyer,G.R., Augustyns,K., Lambeir,A.M., Scharpe,S. and De Meester,I.<br>Dipeptidyl peptidase II and leukocyte cell death<br>Biochem Pharmacol (25-4-2006) 72, 70-79. PubMed  Europe PubMed DOI  I
  20. Maes,M.B., Lambeir,A.M., Van der Veken,P., De Winter,B., Augustyns,K., Scharpe,S. and De Meester,I.<br>In vivo effects of a potent, selective DPPII inhibitor: UAMC00039 is a possible tool for the elucidation of the physiological function of DPPII<br>Adv Exp Med Biol (2006) 575, 73-85. PubMed  Europe PubMed DOI  I
  21. [YEAR:14-7-2006]Soroka,A., Van der Veken,P., De Meester,I., Lambeir,A.M., Maes,M.B., Scharpe,S., Haemers,A. and Augustyns,K.<br>Synthesis and dipeptidyl peptidase inhibition of N-(4-substituted-2,4-diaminobutanoyl)piperidines<br>Bioorg Med Chem Lett (14-7-2006) 16, 4777-4779. PubMed  Europe PubMed DOI  I
    22. 2005
  22. Danilov,A.V., Klein,A.K., Lee,H.J., Baez,D.V. and Huber,B.T.<br>Differential control of G0 programme in chronic lymphocytic leukaemia: a novel prognostic factor<br>Br J Haematol (2005) 128, 472-481. PubMed  Europe PubMed DOI
  23. Hu,Y., Ma,L., Wu,M., Wong,M.S., Li,B., Corral,S., Yu,Z., Nomanbhoy,T., Alemayehu,S., Fuller,S.R., Rosenblum,J.S., Rozenkrants,N., Minimo,L.C., Ripka,W.C., Szardenings,A.K., Kozarich,J.W. and Shreder,K.R.<br>Synthesis and structure-activity relationship of N-alkyl Gly-boro-Pro inhibitors of DPP4, FAP, and DPP7<br>Bioorg Med Chem Lett (2005) 15, 4239-4242. PubMed  Europe PubMed DOI  I
  24. Lankas,G.R., Leiting,B., Roy,R.S., Eiermann,G.J., Beconi,M.G., Biftu,T., Chan,C.C., Edmondson,S., Feeney,W.P., He,H., Ippolito,D.E., Kim,D., Lyons,K.A., Ok,H.O., Patel,R.A., Petrov,A.N., Pryor,K.A., Qian,X., Reigle,L., Woods,A., Wu,J.K., Zaller,D., Zhang,X., Zhu,L., Weber,A.E. and Thornberry,N.A.<br>Dipeptidyl peptidase IV inhibition for the treatment of type 2 diabetes: potential importance of selectivity over dipeptidyl peptidases 8 and 9<br>Diabetes (2005) 54, 2988-2994. PubMed  Europe PubMed DOI  I
  25. [YEAR:18-11-2005]Maes,M.B., Lambeir,A.M., Gilany,K., Senten,K., Van der Veken,P., Leiting,B., Augustyns,K., Scharpe,S. and De Meester,I.<br>Kinetic investigation of human dipeptidyl peptidase II (DPPII)-mediated hydrolysis of dipeptide derivatives and its identification as quiescent cell proline dipeptidase (QPP)/dipeptidyl peptidase 7 (DPP7)<br>Biochem J (18-11-2005) 386, 315-324. PubMed  Europe PubMed DOI  PMC  EPMC
  26. Shreder,K.R., Wong,M.S., Corral,S., Yu,Z., Winn,D.T., Wu,M., Hu,Y., Nomanbhoy,T., Alemayehu,S., Fuller,S.R., Rosenblum,J.S. and Kozarich,J.W.<br>Boro-norleucine as a P1 residue for the design of selective and potent DPP7 inhibitors<br>Bioorg Med Chem Lett (2005) 15, 4256-4260. PubMed  Europe PubMed DOI  I
  27. [YEAR:24-3-2005]Van der Veken,P., Senten,K., Kertesz,I., De Meester,I., Lambeir,A.M., Maes,M.B., Scharpe,S., Haemers,A. and Augustyns,K.<br>Fluoro-olefins as peptidomimetic inhibitors of dipeptidyl peptidases<br>J Med Chem (24-3-2005) 48, 1768-1780. PubMed  Europe PubMed DOI  I
    28. 2004
  28. McDonald,J.K. and Ohkubo,I.<br>Dipeptidyl-peptidase II<br>[ISSN:0-12-079610-4] (2004) 2, 1938-1943.  V
  29. [YEAR:20-5-2004]Senten,K., Van der Veken,P., De Meester,I., Lambeir,A.M., Scharpe,S., Haemers,A. and Augustyns,K.<br>Gamma-amino-substituted analogues of 1-[(S)-2,4-diaminobutanoyl]piperidine as highly potent and selective dipeptidyl peptidase II inhibitors<br>J Med Chem (20-5-2004) 47, 2906-2916. PubMed  Europe PubMed DOI  I
    30. 2003
  30. [YEAR:15-4-2003]Leiting,B., Pryor,K.D., Wu,J.K., Marsilio,F., Patel,R.A., Craik,C.S., Ellman,J.A., Cummings,R.T. and Thornberry,N.A.<br>Catalytic properties and inhibition of proline-specific dipeptidyl peptidases II, IV and VII<br>Biochem J (15-4-2003) 371, 525-532. PubMed  Europe PubMed DOI  PMC  EPMC  P
  31. [YEAR:6-11-2003]Senten,K., Van der Veken,P., De Meester,I., Lambeir,A.M., Scharpe,S., Haemers,A. and Augustyns,K.<br>Design, synthesis, and SAR of potent and selective dipeptide-derived inhibitors for dipeptidyl peptidases<br>J Med Chem (6-11-2003) 46, 5005-5014. PubMed  Europe PubMed DOI  I
    32. 2002
  32. [YEAR:21-10-2002]Senten,K., Van der Veken,P., Bal,G., De Meester,I., Lambeir,A.M., Scharpe,S., Bauvois,B., Haemers,A. and Augustyns,K.<br>Development of potent and selective dipeptidyl peptidase II inhibitors<br>Bioorg Med Chem Lett (21-10-2002) 12, 2825-2828. PubMed  Europe PubMed DOI  I
    33. 2001
  33. Araki,H., Li,Y., Yamamoto,Y., Haneda,M., Nishi,K., Kikkawa,R. and Ohkubo,I.<br>Purification, molecular cloning, and immunohistochemical localization of dipeptidyl peptidase II from the rat kidney and its identity with quiescent cell proline dipeptidase<br>J Biochem (2001) 129, 279-288. PubMed  Europe PubMed
  34. [YEAR:15-1-2001]Fukasawa,K.M., Fukasawa,K., Higaki,K., Shiina,N., Ohno,M., Ito,S., Otogoto,J. and Ota,N.<br>Cloning and functional expression of rat kidney dipeptidyl peptidase II<br>Biochem J (15-1-2001) 353, 283-290. PubMed  Europe PubMed DOI  PMC  EPMC
    35. 2000
  35. [YEAR:15-11-2000]Chiravuri,M., Agarraberes,F., Mathieu,S.L., Lee,H. and Huber,B.T.<br>Vesicular localization and characterization of a novel post-proline-cleaving aminodipeptidase, quiescent cell proline dipeptidase<br>J Immunol (15-11-2000) 165, 5695-5702. PubMed  Europe PubMed
  36. [YEAR:1-9-2000]Chiravuri,M., Lee,H., Mathieu,S.L. and Huber,B.T.<br>Homodimerization via a leucine zipper motif is required for enzymatic activity of quiescent cell proline dipeptidase<br>J Biol Chem (1-9-2000) 275, 26994-26999. PubMed  Europe PubMed DOI
  37. Dikov,A., Dimitrova,M., Pajpanova,T., Krieg,R. and Halbhuber,K.J.<br>Histochemical method for dipeptidyl aminopeptidase II with a new anthraquinonyl hydrazide substrate<br>Cell Mol Biol (Noisy-le-grand) (2000) 46, 1213-1218. PubMed  Europe PubMed  L
  38. [YEAR:15-6-2000]Stockel-Maschek,A., Mrestani-Klaus,C., Stiebitz,B., Demuth,H. and Neubert,K.<br>Thioxo amino acid pyrrolidides and thiazolidides: new inhibitors of proline specific peptidases<br>Biochim Biophys Acta (15-6-2000) 1479, 15-31. PubMed  Europe PubMed DOI  I
    39. 1999
  39. [YEAR:15-9-1999]Chiravuri,M., Schmitz,T., Yardley,K., Underwood,R., Dayal,Y. and Huber,B.T.<br>A novel apoptotic pathway in quiescent lymphocytes identified by inhibition of a post-proline cleaving aminodipeptidase: A candidate target protease, quiescent cell proline dipeptidase<br>J Immunol (15-9-1999) 163, 3092-3099. PubMed  Europe PubMed
  40. [YEAR:26-11-1999]Underwood,R., Chiravuri,M., Lee,H., Schmitz,T., Kabcenell,A.K., Yardley,K. and Huber,B.T.<br>Sequence, purification, and cloning of an intracellular serine protease, quiescent cell proline dipeptidase<br>J Biol Chem (26-11-1999) 274, 34053-34058. PubMed  Europe PubMed DOI
    41. 1998
  41. Akiyama,T., Harada,S., Kojima,F., Kinoshita,N., Hamada,M., Muraoka,Y., Aoyagi,T. and Takeuchi,T.<br>Epostatin, new inhibitor of dipeptidyl peptidase II, produced by Streptomyces sp. MJ995-OF5. I. Taxonomy of producing strain, fermentation, isolation, physico-chemical properties and biological properties<br>J Antibiot (Tokyo) (1998) 51, 253-260. PubMed  Europe PubMed  I
  42. Akiyama,T., Sawa,R., Naganawa,H., Muraoka,Y., Aoyagi,T. and Takeuchi,T.<br>Epostatin, new inhibitor of dipeptidyl peptidase II, produced by Streptomyces sp. MJ995-OF5 II. Structure elucidation<br>J Antibiot (Tokyo) (1998) 51, 372-373. PubMed  Europe PubMed  I
    43. 1996
  43. Dunn,A.D., Myers,H.E. and Dunn,J.T.<br>The combined action of two thyroidal proteases releases T4 from the dominant hormone-forming site of thyroglobulin<br>Endocrinology (1996) 137, 3279-3285. PubMed  Europe PubMed DOI
  44. Huang,K., Takagaki,M., Kani,K. and Ohkubo,I.<br>Dipeptidyl peptidase II from porcine seminal plasma: purification, characterization, and its homology to granzymes, cytotoxic cell proteinases (CCP 1-4)<br>Biochim Biophys Acta (1996) 1290, 149-156. PubMed  Europe PubMed DOI  I
  45. Rawlings,N.D. and Barrett,A.J.<br>Dipeptidyl-peptidase II is related to lysosomal Pro-X carboxypeptidase<br>Biochim Biophys Acta (1996) 1298, 1-3. PubMed  Europe PubMed DOI
    46. 1995
  46. Struckhoff,G.<br>Transforming growth factor beta1 and parathyroid hormone-related protein control the secretion of dipeptidyl peptidase II by rat astrocytes<br>Neurosci Lett (1995) 189, 117-120. PubMed  Europe PubMed DOI
    47. 1993
  47. [YEAR:20-8-1993]Struckhoff,G.<br>Dipeptidyl peptidase II in astrocytes of the rat brain. Meningeal cells increase enzymic activity in cultivated astrocytes<br>Brain Res (20-8-1993) 620, 49-57. PubMed  Europe PubMed DOI
    48. 1988
  48. [YEAR:8-7-1988]Stevens,B.R., Fernandez,A., Sumners,C. and Hearing,L.<br>Neonatal rat brain astroglial dipeptidyl peptidase II activity regulation by cations and anions<br>Neurosci Lett (8-7-1988) 89, 319-322. PubMed  Europe PubMed
    49. 1986
  49. McDonald,J.K. and Barrett,A.J.<br>Mammalian Proteases: a Glossary and Bibliography. Volume 2: Exopeptidases<br>[ISSN:ISBN 0-12-079502-7] (1986)
  50. [YEAR:15-5-1986]Struckhoff,G. and Heymann,E.<br>Rat peritoneal mast cells release dipeptidyl peptidase II<br>Biochem J (15-5-1986) 236, 215-219. PubMed  Europe PubMed  PMC  EPMC
    51. 1985
  51. [YEAR:15-5-1985]Nagatsu,T., Sakai,T., Kojima,K., Araki,E., Sakakibara,S., Fukasawa,K. and Harada,M.<br>A sensitive and specific assay for dipeptidyl-aminopeptidase II in serum and tissues by liquid chromatography-fluorometry<br>Anal Biochem (15-5-1985) 147, 80-85. PubMed  Europe PubMed
    52. 1981
  52. Stauber,W.T. and Ong,S.H.<br>Fluorescence demonstration of dipeptidyl peptidase II in skeletal, cardiac, and vascular smooth muscles<br>J Histochem Cytochem (1981) 29, 672-677. PubMed  Europe PubMed
    53. 1980
  53. [YEAR:6-11-1980]McDonald,J.K. and Schwabe,C.<br>Dipeptidyl peptidase II of bovine dental pulp. Initial demonstration and characterization as a fibroblastic, lysosomal peptidase of the serine class active on collagen-related peptides<br>Biochim Biophys Acta (6-11-1980) 616, 68-81. PubMed  Europe PubMed  I
    54. 1979
  54. Smith,R.E. and Dean,P.N.<br>A study of acid phosphatase and dipeptidyl aminopeptidase II in monodispersed anterior pituitary cells using flow cytometry and electron microscopy<br>J Histochem Cytochem (1979) 27, 1499-1504. PubMed  Europe PubMed
    55. 1977
  55. McDonald,J.K. and Schwabe,C.<br>Intracellular exopeptidases<br> (1977) , 311-391.
    56. 1969
  56. Hopsu-Havu,V.K. and Jansen,C.T.<br>Peptidases in the skin. II. Demonstration and partial separation of several specific dipeptide naphthylamidases in the rat and human skin<br>Arch Klin Exp Dermatol (1969) 235, 53-62. PubMed  Europe PubMed DOI
    57. 1968
  57. [YEAR:10-8-1968]McDonald,J.K., Leibach,F.H., Grindeland,R.E. and Ellis,S.<br>Purification of dipeptidyl aminopeptidase II (dipeptidyl arylamidase II) of the anterior pituitary gland. Peptidase and dipeptide esterase activities<br>J Biol Chem (10-8-1968) 243, 4143-4150. PubMed  Europe PubMed
  58. McDonald,J.K., Reilly,T.J., Zeitman,B.B. and Ellis,S.<br>Dipeptidyl arylamidase II of the pituitary. Properties of lysylalanyl-beta-naphthylamide hydrolysis: inhibition by cations, distribution in tissues, and subcellular localization<br>J Biol Chem (1968) 243, 2028-2037. PubMed  Europe PubMed  I

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