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Literature for peptidase S26.001: signal peptidase I

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: A Assay, S Structure, T Target, P Specificity, I Inhibitor, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2023
  1. Koehler,M.F.T., Chen,Y.C., Chen,Y., Chen,Y., Crawford,J.J., Durk,M.R., Garland,K., Hanan,E.J., Higuchi,R.I., Hu,H., Ly,C.Q., Paraselli,P.G., Roberts,T.C., Schwarz,J.B., Smith,P.A., Yu,Z. and Heise,C.E.
    Lipid Tales: Optimizing Arylomycin Membrane Anchors
    ACS Med Chem Lett14, 1524-1530. PubMed  Europe PubMed DOI  I
  2. Niu,M., Gu,X., Yang,J., Cui,H., Hou,X., Ma,Y., Wang,C. and Wei,G.
    Dual-Mechanism Glycolipidpeptide with High Antimicrobial Activity, Immunomodulatory Activity, and Potential Application for Combined Antibacterial Therapy
    ACS Nano17, 6292-6316. PubMed  Europe PubMed DOI
    3. 2022
  3. Musik,J.E., Zalucki,Y.M., Beacham,I.R. and Jennings,M.P.
    The role of signal sequence proximal residues in the mature region of bacterial secreted proteins in E. coli
    Biochim Biophys Acta Biomembr1864, 184000-184000. PubMed  Europe PubMed DOI  V
  4. Szalaj,N., Benediktsdottir,A., Rusin,D., Karlen,A., Mowbray,S.L. and Wieckowska,A.
    Bacterial type I signal peptidase inhibitors - Optimized hits from nature
    Eur J Med Chem238, 114490-114490. PubMed  Europe PubMed DOI  V
  5. Zanotti,A., Coelho,J.P.L., Kaylani,D., Singh,G., Tauber,M., Hitzenberger,M., Avci,D., Zacharias,M., Russell,R.B., Lemberg,M.K. and Feige,M.J.
    The human signal peptidase complex acts as a quality control enzyme for membrane proteins
    Science378, 996-1000. PubMed  Europe PubMed DOI
    6. 2021
  6. Benediktsdottir,A., Lu,L., Cao,S., Zamaratski,E., Karlen,A., Mowbray,S.L., Hughes,D. and Sandstrom,A.
    Antibacterial sulfonimidamide-based oligopeptides as type I signal peptidase inhibitors: Synthesis and biological evaluation
    Eur J Med Chem224, 113699-113699. PubMed  Europe PubMed DOI
  7. Girgis,H.S., DuPai,C.D., Lund,J., Reeder,J., Guillory,J., Durinck,S., Liang,Y., Kaminker,J., Smith,P.A. and Skippington,E.
    Single-molecule nanopore sequencing reveals extreme target copy number heterogeneity in arylomycin-resistant mutants
    Proc Natl Acad Sci U S A118, PubMed  Europe PubMed DOI  I
    8. 2020
  8. Mu,Y., Bintintan,I. and Meyers,G.
    Downstream sequences control the processing of the pestivirus E(rns)-E1 precursor
    J Virol PubMed  Europe PubMed DOI
  9. Tan,Y.X., Peters,D.S., Walsh,S.I., Holcomb,M., Santos-Martins,D., Forli,S. and Romesberg,F.E.
    Initial Analysis of the Arylomycin D Antibiotics
    J Nat Prod83, 2112-2121. PubMed  Europe PubMed DOI  I
    10. 2019
  10. Musik,J.E., Zalucki,Y.M., Day,C.J. and Jennings,M.P.
    Efficient function of signal peptidase 1 of Escherichia coli is partly determined by residues in the mature N-terminus of exported proteins
    Biochim Biophys Acta Biomembr1861, 1018-1022. PubMed  Europe PubMed DOI  P
    11. 2018
  11. Smith,P.A., Koehler,M.F.T., Girgis,H.S., Yan,D., Chen,Y., Chen,Y., Crawford,J.J., Durk,M.R., Higuchi,R.I., Kang,J., Murray,J., Paraselli,P., Park,S., Phung,W., Quinn,J.G., Roberts,T.C., Rouge,L., Schwarz,J.B., Skippington,E., Wai,J., Xu,M., Yu,Z., Zhang,H., Tan,M.W. and Heise,C.E.
    Optimized arylomycins are a new class of Gram-negative antibiotics
    Nature561, 189-194. PubMed  Europe PubMed DOI  I
  12. Szalaj,N., Lu,L., Benediktsdottir,A., Zamaratski,E., Cao,S., Olanders,G., Hedgecock,C., Karlen,A., Erdelyi,M., Hughes,D., Mowbray,S.L. and Brandt,P.
    Boronic ester-linked macrocyclic lipopeptides as serine protease inhibitors targeting Escherichia coli type I signal peptidase
    Eur J Med Chem157, 1346-1360. PubMed  Europe PubMed DOI  I
  13. Yeh,C.H., Walsh,S.I., Craney,A., Tabor,M.G., Voica,A.F., Adhikary,R., Morris,S.E. and Romesberg,F.E.
    Optimization of a beta-lactam scaffold for antibacterial activity via the inhibition of bacterial type I signal peptidase
    ACS Med Chem Lett9, 376-380. PubMed  Europe PubMed DOI  I
    14. 2017
  14. De Rosa,M., Lu,L., Zamaratski,E., Szalaj,N., Cao,S., Wadensten,H., Lenhammar,L., Gising,J., Roos,A.K., Huseby,D.L., Larsson,R., Andren,P.E., Hughes,D., Brandt,P., Mowbray,S.L. and Karlen,A.
    Design, synthesis and in vitro biological evaluation of oligopeptides targeting E. coli type I signal peptidase (LepB)
    Bioorg Med Chem25, 897-911. PubMed  Europe PubMed DOI  I
  15. Muhammad,M.A., Falak,S., Rashid,N., Gardner,Q.A., Ahmad,N., Imanaka,T. and Akhtar,M.
    Escherichia coli signal peptidase recognizes and cleaves archaeal signal sequence
    Biochemistry (Mosc)82, 821-825. PubMed  Europe PubMed DOI  P
  16. Zalucki,Y.M. and Jennings,M.P.
    Signal peptidase I processed secretory signal sequences: selection for and against specific amino acids at the second position of mature protein
    Biochem Biophys Res Commun483, 972-977. PubMed  Europe PubMed DOI  P
    17. 2016
  17. Walsh,S.I., Craney,A. and Romesberg,F.E.
    Not just an antibiotic target: exploring the role of type I signal peptidase in bacterial virulence
    Bioorg Med Chem24, 6370-6378. PubMed  Europe PubMed DOI  T
  18. Wei,T., Chisholm,J. and Sanfacon,H.
    Characterization of a non-canonical signal peptidase cleavage site in a replication protein from tomato ringspot virus
    PLoS ONE11, e0162223-e0162223. PubMed  Europe PubMed DOI
    19. 2015
  19. Craney,A. and Romesberg,F.E.
    The inhibition of type I bacterial signal peptidase: biological consequences and therapeutic potential
    Bioorg Med Chem Lett25, 4761-4766. PubMed  Europe PubMed DOI  V  I
  20. Craney,A., Dix,M.M., Adhikary,R., Cravatt,B.F. and Romesberg,F.E.
    An alternative terminal step of the general secretory pathway in Staphylococcus aureus
    MBio6, PubMed  Europe PubMed DOI  I
    21. 2014
  21. Bhanu,M.K. and Kendall,D.A.
    Fluorescence spectroscopy of soluble E. coli SPase I Delta2-75 reveals conformational changes in response to ligand binding
    Proteins82, 596-606. PubMed  Europe PubMed DOI
  22. Paetzel,M.
    Structure and mechanism of Escherichia coli type I signal peptidase
    Biochim Biophys Acta1843, 1497-1508. PubMed  Europe PubMed DOI  V
  23. Personne,Y., Curtis,M.A., Wareham,D.W. and Waite,R.D.
    Activity of the type I signal peptidase inhibitor MD3 against multidrug-resistant Gram-negative bacteria alone and in combination with colistin
    J Antimicrob Chemother69, 3236-3243. PubMed  Europe PubMed DOI  I
    24. 2013
  24. Ivankov,D.N., Payne,S.H., Galperin,M.Y., Bonissone,S., Pevzner,P.A. and Frishman,D.
    How many signal peptides are there in bacteria?
    Environ Microbiol15, 983-990. PubMed  Europe PubMed DOI  P
    25. 2012
  25. Auclair,S.M., Bhanu,M.K. and Kendall,D.A.
    Signal peptidase I: cleaving the way to mature proteins
    Protein Sci21, 13-25. PubMed  Europe PubMed DOI  T
  26. Dalbey,R.E.
    Signal peptidase I
    [ISSN:978-0-12-407742-3]3, 3493-3497. DOI
  27. De Bona,P., Deshmukh,L., Gorbatyuk,V., Vinogradova,O. and Kendall,D.A.
    Structural studies of a signal peptide in complex with signal peptidase I cytoplasmic domain: the stabilizing effect of membrane-mimetics on the acquired fold
    Proteins80, 807-817. PubMed  Europe PubMed DOI  S
  28. Liao,G.J., He,Y. and Xie,J.P.
    [Novel inhibitors against the bacterial signal peptidase I]
    Yao Xue Xue Bao47, 1561-1566. PubMed  Europe PubMed  V  T  I
  29. Waite,R.D., Rose,R.S., Rangarajan,M., Aduse-Opoku,J., Hashim,A. and Curtis,M.A.
    Pseudomonas aeruginosa possesses two putative type I signal peptidases, LepB and PA1303, each with distinct roles in physiology and virulence
    J Bacteriol194, 4521-4536. PubMed  Europe PubMed DOI
    30. 2011
  30. Crauste,C., Froeyen,M., Anne,J. and Herdewijn,P.
    Asymmetric synthesis of new beta-lactam lipopeptides as bacterial signal peptidase I inhibitors
    Eur J Org Chem2011, 3437-3449. DOI  I
  31. Liu,J., Luo,C., Smith,P.A., Chin,J.K., Page,M.G., Paetzel,M. and Romesberg,F.E.
    Synthesis and characterization of the arylomycin lipoglycopeptide antibiotics and the crystallographic analysis of their complex with signal peptidase
    J Am Chem Soc133, 17869-17877. PubMed  Europe PubMed DOI  S  I
  32. Park,K.H., Billon-Denis,E., Dahmane,T., Lebaupain,F., Pucci,B., Breyton,C. and Zito,F.
    In the cauldron of cell-free synthesis of membrane proteins: playing with new surfactants
    N Biotechnol28, 255-261. PubMed  Europe PubMed DOI  E
  33. Rao Cv,S. and Ann,J.
    Bacterial type I signal peptidases as antibiotic targets
    Future Microbiol6, 1279-1296. PubMed  Europe PubMed DOI  T
  34. Roberts,T.C., Schallenberger,M.A., Liu,J., Smith,P.A. and Romesberg,F.E.
    Initial efforts toward the optimization of arylomycins for antibiotic activity
    J Med Chem54, 4954-4963. PubMed  Europe PubMed DOI  I
  35. Smith,P.A., Powers,M.E., Roberts,T.C. and Romesberg,F.E.
    In vitro activities of arylomycin natural-product antibiotics against Staphylococcus epidermidis and other coagulase-negative staphylococci
    Antimicrob Agents Chemother55, 1130-1134. PubMed  Europe PubMed DOI  I
    36. 2010
  36. Wang,P. and Dalbey,R.E.
    In vitro and in vivo approaches to studying the bacterial signal peptide processing
    Methods Mol Biol619, 21-37. PubMed  Europe PubMed DOI  V
    37. 2009
  37. Harris,D.A., Powers,M.E. and Romesberg,F.E.
    Synthesis and biological evaluation of penem inhibitors of bacterial signal peptidase
    Bioorg Med Chem Lett19, 3787-3790. PubMed  Europe PubMed DOI  I
  38. Luke,I., Handford,J.I., Palmer,T. and Sargent,F.
    Proteolytic processing of Escherichia coli twin-arginine signal peptides by LepB
    Arch Microbiol191, 919-925. PubMed  Europe PubMed DOI
  39. Luo,C., Roussel,P., Dreier,J., Page,M.G. and Paetzel,M.
    Crystallographic analysis of bacterial signal peptidase in ternary complex with arylomycin A2 and a beta-sultam inhibitor
    Biochemistry48, 8976-8984. PubMed  Europe PubMed DOI  S  I
    40. 2008
  40. Choo,K.H. and Ranganathan,S.
    Flanking signal and mature peptide residues influence signal peptide cleavage
    BMC Bioinformatics9 Suppl 12, S15-S15. PubMed  Europe PubMed DOI  P
  41. Choo,K.H., Tong,J.C. and Ranganathan,S.
    Modeling Escherichia coli signal peptidase complex with bound substrate: determinants in the mature peptide influencing signal peptide cleavage
    BMC Bioinformatics9 Suppl 1, S15-S15. PubMed  Europe PubMed DOI
  42. Kim,Y.T., Yoshida,H., Kojima,M., Kurita,R., Nishii,W., Muramatsu,T., Ito,H., Park,S.J. and Takahashi,K.
    The effects of mutations in the carboxyl-terminal region on the catalytic activity of Escherichia coli signal peptidase I
    J Biochem143, 237-242. PubMed  Europe PubMed DOI
  43. Li,T., Froeyen,M. and Herdewijn,P.
    Computational alanine scanning and free energy decomposition for E. coli type I signal peptidase with lipopeptide inhibitor complex
    J Mol Graph Model26, 813-823. PubMed  Europe PubMed DOI  I
  44. Musial-Siwek,M., Yeagle,P.L. and Kendall,D.A.
    A small subset of signal peptidase residues are perturbed by signal peptide binding
    Chem Biol Drug Des72, 140-146. PubMed  Europe PubMed DOI
  45. Musial-Siwek,M., Kendall,D.A. and Yeagle,P.L.
    Solution NMR of signal peptidase, a membrane protein
    Biochim Biophys Acta1778, 937-944. PubMed  Europe PubMed DOI  S
    46. 2007
  46. Ekici,O.D., Karla,A., Paetzel,M., Lively,M.O., Pei,D. and Dalbey,R.E.
    Altered -3 substrate specificity of Escherichia coli signal peptidase 1 mutants as revealed by screening a combinatorial peptide library
    J Biol Chem282, 417-425. PubMed  Europe PubMed DOI
    47. 2005
  47. Catrein,I., Herrmann,R., Bosserhoff,A. and Ruppert,T.
    Experimental proof for a signal peptidase I like activity in Mycoplasma pneumoniae, but absence of a gene encoding a conserved bacterial type I SPase
    FEBS J272, 2892-2900. PubMed  Europe PubMed DOI
  48. [YEAR:14-12-2005]Karla,A., Lively,M.O., Paetzel,M. and Dalbey,R.
    The identification of residues that control signal peptidase cleavage fidelity and substrate specificity
    J Biol Chem280, 6731-6741. PubMed  Europe PubMed DOI  P  I
    49. 2004
  49. Dalbey,R.E.
    Signal peptidase I
    [ISSN:0-12-079610-4]2, 1981-1985.  V
  50. Houben,E.N., ten Hagen-Jongman,C.M., Brunner,J., Oudega,B. and Luirink,J.
    The two membrane segments of leader peptidase partition one by one into the lipid bilayer via a Sec/YidC interface
    EMBO Rep5, 970-975. PubMed  Europe PubMed DOI
  51. Kim,Y.T., Kurita,R., Kojima,M., Nishii,W., Tanokura,M., Muramatsu,T., Ito,H. and Takahashi,K.
    Identification of arginine residues important for the activity of Escherichia coli signal peptidase I
    Biol Chem385, 381-388. PubMed  Europe PubMed DOI
  52. [YEAR:1-6-2004]Kulanthaivel,P., Kreuzman,A.J., Strege,M.A., Belvo,M.D., Smitka,T.A., Clemens,M., Swartling,J.R., Minton,K.L., Zheng,F., Angleton,E.L., Mullen,D., Jungheim,L.N., Klimkowski,V.J., Nicas,T.I., Thompson,R.C. and Peng,S.B.
    Novel lipoglycopeptides as inhibitors of bacterial signal peptidase I
    J Biol Chem279, 36250-36258. PubMed  Europe PubMed DOI  I
  53. Lammertyn,E., Van Mellaert,L., Meyen,E., Lebeau,I., De Buck,E., Anne,J. and Geukens,N.
    Molecular and functional characterization of type I signal peptidase from Legionella pneumophila
    Microbiology (Reading, Engl )150, 1475-1483. PubMed  Europe PubMed  I
  54. [YEAR:10-5-2004]Paetzel,M., Goodall,J.J., Kania,M., Dalbey,R.E. and Page,M.G.
    Crystallographic and biophysical analysis of a bacterial signal peptidase in complex with a lipopeptide-based inhibitor
    J Biol Chem279, 30781-30790. PubMed  Europe PubMed DOI  S  I
  55. [YEAR:13-1-2004]Wang,Y., Bruckner,R. and Stein,R.L.
    Regulation of signal peptidase by phospholipids in membrane: characterization of phospholipid bilayer incorporated Escherichia coli signal peptidase
    Biochemistry43, 265-270. PubMed  Europe PubMed DOI
    56. 2003
  56. [YEAR:10-10-2003]Linde,D., Marischen,L. and Muller,J.P.
    Characterisation of preYvaY export reveals differences in the substrate specificities of Bacillus subtilis and Escherichia coli leader peptidases
    FEMS Microbiol Lett227, 149-156. PubMed  Europe PubMed DOI
  57. Rahman,M.S., Simser,J.A., Macaluso,K.R. and Azad,A.F.
    Molecular and functional analysis of the lepB gene, encoding a type I signal peptidase from Rickettsia rickettsii and Rickettsia typhi
    J Bacteriol185, 4578-4584. PubMed  Europe PubMed DOI
    58. 2002
  58. Barbosa,M.D., Lin,S., Markwalder,J.A., Mills,J.A., DeVito,J.A., Teleha,C.A., Garlapati,V., Liu,C., Thompson,A., Trainor,G.L., Kurilla,M.G. and Pompliano,D.L.
    Regulated expression of the Escherichia coli lepB gene as a tool for cellular testing of antimicrobial compounds that inhibit signal peptidase I in vitro
    Antimicrobial Agents Chemother46, 3549-3554. PubMed  Europe PubMed DOI  I
  59. [YEAR:15-3-2002]Paetzel,M., Dalbey,R.E. and Strynadka,N.C.
    Crystal structure of a bacterial signal peptidase apoenzyme: implications for signal peptide binding and the Ser-Lys dyad mechanism
    J Biol Chem277, 9512-9519. PubMed  Europe PubMed DOI  S
  60. Paetzel,M., Karla,A., Strynadka,N.C. and Dalbey,R.E.
    Signal peptidases
    Chem Rev102, 4549-4580. PubMed  Europe PubMed DOI  V
    61. 2001
  61. de Zamaroczy,M., Mora,L., Lecuyer,A., Li,V. and Buckingham,R.H.
    Cleavage of colicin D is necessary for cell killing and requires the inner membrane peptidase LepB
    Mol Cell8, 159-168. PubMed  Europe PubMed DOI
  62. [YEAR:26-11-2001]Gallagher,J., Kaderbhai,N.N. and Kaderbhai,M.A.
    Kinetic constants of signal peptidase I using cytochrome b5 as a precursor substrate
    Biochim Biophys Acta1550, 1-5. PubMed  Europe PubMed DOI
    63. 2000
  63. [YEAR:20-6-2000]Carlos,J.L., Klenotic,P.A., Paetzel,M., Strynadka,N.C. and Dalbey,R.E.
    Mutational evidence of transition state stabilization by Serine 88 in Escherichia coli type I signal peptidase
    Biochemistry39, 7276-7283. PubMed  Europe PubMed DOI
  64. [YEAR:8-12-2000]Carlos,J.L., Paetzel,M., Brubaker,G., Karla,A., Ashwell,C.M., Lively,M.O., Cao,G., Bullinger,P. and Dalbey,R.E.
    The role of the membrane-spanning domain of type I signal peptidases in substrate cleavage site selection
    J Biol Chem275, 38813-38822. PubMed  Europe PubMed DOI
  65. [YEAR:7-7-2000]Houben,E.N.G., Scotti,P.A., Valent,Q.A., Brunner,J., De Gier,J.W.L., Oudega,B. and Luirink,J.
    Nascent Lep inserts into the Escherichia coli inner membrane in the vicinity of YidC, SecY and SecA
    FEBS Lett476, 229-233. PubMed  Europe PubMed DOI
  66. [YEAR:3-3-2000]Klenotic,P.A., Carlos,J.L., Samuelson,J.C., Schuenemann,T.A., Tschantz,W.R., Paetzel,M., Strynadka,N.C. and Dalbey,R.E.
    The role of the conserved Box E residues in the active site of the Escherichia coli type I signal peptidase
    J Biol Chem275, 6490-6498. PubMed  Europe PubMed DOI
  67. Paetzel,M., Dalbey,R.E. and Strynadka,N.C.
    The structure and mechanism of bacterial type I signal peptidases. A novel antibiotic target
    Pharmacol Ther87, 27-49. PubMed  Europe PubMed DOI  T  I
  68. [YEAR:11-7-2000]Stein,R.L., Barbosa,M.D. and Bruckner,R.
    Kinetic and mechanistic studies of signal peptidase I from Escherichia coli
    Biochemistry39, 7973-7983. PubMed  Europe PubMed DOI
    69. 1999
  69. Paetzel,M. and Strynadka,N.C.
    Common protein architecture and binding sites in proteases utilizing a Ser/Lys dyad mechanism
    Protein Sci8, 2533-2536. PubMed  Europe PubMed DOI  S
    70. 1998
  70. Bairl,A. and Muller,P.
    A second gene for type I signal peptidase in Bradyrhizobium japonicum, sipF, is located near genes involved in RNA processing and cell division
    Mol Gen Genet260, 346-356. PubMed  Europe PubMed DOI
  71. Black,M.T. and Bruton,G.
    Inhibitors of bacterial signal peptidases
    Curr Pharm Des4, 133-154. PubMed  Europe PubMed  V  I
  72. [YEAR:12-11-1998]Paetzel,M., Dalbey,R.E. and Strynadka,N.C.
    Crystal structure of a bacterial signal peptidase in complex with a beta-lactam inhibitor
    Nature396, 186-190. PubMed  Europe PubMed DOI  S  I
  73. [YEAR:10-7-1998]van Klompenburg,W., Paetzel,M., de Jong,J.M., Dalbey,R.E., Demel,R.A., von Heijne,G. and De Kruijff,B.
    Phosphatidylethanolamine mediates insertion of the catalytic domain of leader peptidase in membranes
    FEBS Lett431, 75-79. PubMed  Europe PubMed DOI
  74. [YEAR:1-1-1998]Zhong,W. and Benkovic,S.J.
    Development of an internally quenched fluorescent substrate for Escherichia coli leader peptidase
    Anal Biochem255, 66-73. PubMed  Europe PubMed DOI
    75. 1997
  75. Dalbey,R.E., Lively,M.O., Bron,S. and van Dijl,J.M.
    The chemistry and enzymology of the type I signal peptidases
    Protein Sci6, 1129-1138. PubMed  Europe PubMed DOI
  76. Klug,G., Jager,A., Heck,C. and Rauhut,R.
    Identification, sequence analysis, and expression of the lepB gene for a leader peptidase in Rhodobacter capsulatus
    Mol Gen Genet253, 666-673. PubMed  Europe PubMed DOI  E
  77. [YEAR:11-4-1997]Paetzel,M., Strynadka,N.C., Tschantz,W.R., Casareno,R., Bullinger,P.R. and Dalbey,R.E.
    Use of site-directed chemical modification to study an essential lysine in Escherichia coli leader peptidase
    J Biol Chem272, 9994-10003. PubMed  Europe PubMed DOI
  78. Suciu,D., Chatterjee,S. and Inouye,M.
    Catalytic efficiency of signal peptidase I of Escherichia coli is comparable to that of members of the serine protease family
    Protein Eng10, 1057-1060. PubMed  Europe PubMed
    79. 1996
  79. Allsop,A., Brooks,G., Edwards,P.D., Kaura,A.C. and Southgate,R.
    Inhibitors of bacterial signal peptidase: a series of 6-(substituted oxyethyl)penems
    J Antibiot (Tokyo)49, 921-928. PubMed  Europe PubMed  I
    80. 1995
  80. Allsop,A.E., Brooks,G., Bruton,G., Coulton,S., Edwards,P.D., Hatton,I.K., Kaura,A.C., McLean,S.D., Pearson,N.D., Smale,T.C. and Southgate,R.
    Penem inhibitors of bacterial signal peptidase
    Bioorg Med Chem Lett5, 443-448. DOI  I
  81. Falgout,B. and Markoff,L.
    Evidence that flavivirus NS1-NS2A cleavage is mediated by a membrane-bound host protease in the endoplasmic reticulum
    J Virol69, 7232-7243. PubMed  Europe PubMed
  82. Kim,Y.T., Muramatsu,T. and Takahashi,K.
    Identification of Trp300 as an important residue for Escherichia coli leader peptidase activity
    Eur J Biochem234, 358-362. PubMed  Europe PubMed
  83. Packer,J.C., Andre,D. and Howe,C.J.
    Cloning and sequence analysis of a signal peptidase I from the thermophilic cyanobacterium Phormidium laminosum
    Plant Mol Biol27, 199-204. PubMed  Europe PubMed
  84. Paetzel,M., Chernaia,M., Strynadka,N., Tschantz,W., Cao,G., Dalbey,R.E. and James,M.N.
    Crystallization of a soluble, catalytically active form of Escherichia coli leader peptidase
    Proteins23, 122-125. PubMed  Europe PubMed DOI
    85. 1994
  85. Barkocy-Gallagher,G.A., Cannon,J.G. and Bassford,P.J., Jr.
    beta-Turn formation in the processing region is important for efficient maturation of Escherichia coli maltose-binding protein by signal peptidase I in vivo
    J Biol Chem269, 13609-13613. PubMed  Europe PubMed
  86. Kuo,D., Weidner,J., Griffin,P., Shah,S.K. and Knight,W.B.
    Determination of the kinetic parameters of Escherichia coli leader peptidase activity using a continuous assay: the pH dependence and time-dependent inhibition by beta-lactams are consistent with a novel serine protease mechanism
    Biochemistry33, 8347-8354. PubMed  Europe PubMed DOI  A  I
  87. Tschantz,W.R. and Dalbey,R.E.
    Bacterial leader peptidase 1
    Methods Enzymol244, 285-301. PubMed  Europe PubMed DOI  V
    88. 1993
  88. Black,M.T.
    Evidence that the catalytic activity of prokaryote leader peptidase depends upon the operation of a serine-lysine catalytic dyad
    J Bacteriol175, 4957-4961. PubMed  Europe PubMed
  89. Kuo,D.W., Chan,H.K., Wilson,C.J., Griffin,P.R., Williams,H. and Knight,W.B.
    Escherichia coli leader peptidase: production of an active form lacking a requirement for detergent and development of peptide substrates
    Arch Biochem Biophys303, 274-280. PubMed  Europe PubMed DOI
  90. [YEAR:25-12-1993]Tschantz,W.R., Sung,M., Delgado-Partin,V.M. and Dalbey,R.E.
    A serine and a lysine residue implicated in the catalytic mechanism of the Escherichia coli leader peptidase
    J Biol Chem268, 27349-27354. PubMed  Europe PubMed
  91. [YEAR:24-8-1993]Whitley,P., Nilsson,L. and von Heijne,G.
    Three-dimensional model for the membrane domain of Escherichia coli leader peptidase based on disulfide mapping
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