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Literature for peptidase S16.001: Lon-A peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors

(Topics flags: A Assay, S Structure, T Target, K Knockout, I Inhibitor, P Specificity, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Ambite,I., Wan,M.L.Y., Tran,H.T., Nazari,A., Chaudhuri,A., Krintel,C., Gomes,I., Sabari,S., Ahmadi,S., Carneiro,A.N.B.M., Ishac,R., Haq,F. and Svanborg,C.
    Multitarget mechanism of MYC inhibition by the bacterial lon protease in disease
    Sci Rep (2025) 15, 6778-6778. PubMed  Europe PubMed DOI  PMC  EPMC
  2. Chang,H.C., Yeh,J.H., Lo,H.H., Liao,C.T. and Hsiao,Y.M.
    Function and transcription of the lon gene in Xanthomonas campestris pv. campestris
    Antonie Van Leeuwenhoek (2025) 118, 174-174. PubMed  Europe PubMed DOI
  3. Cragan,M., Puri,N. and Karzai,A.W.
    Substrate Recognition and Cleavage-Site Preferences of Lon Protease
    J Biol Chem (2025) , 108365-108365. PubMed  Europe PubMed DOI
  4. Gibson,S.E.R., Frost,I., Hierons,S.J., Moses,T., Poon,W.C.K., West,S.A. and Cann,M.J.
    Bacteria encode post-mortem protein catabolism that enables altruistic nutrient recycling
    Nat Commun (2025) 16, 1400-1400. PubMed  Europe PubMed DOI  PMC  EPMC
  5. Wang,H.J., Kuan,Y.E., Ho,M.R. and Chang,C.I.
    Structural basis for the allosteric activation of Lon by the heat shock protein LarA
    Nat Commun (2025) 16, 2212-2212. PubMed  Europe PubMed DOI  PMC  EPMC
  6. Yigit,K. and Chien,P.
    Lon-dependent proteolysis in oxidative stress responses
    J Bacteriol (2025) , e0000525-e0000525. PubMed  Europe PubMed DOI  V
    7. 2024
  7. Sanyal,S., Kouznetsova,A., Strom,L. and Bjorkegren,C.
    A system for inducible mitochondria-specific protein degradation in vivo
    Nat Commun (2024) 15, 1454-1454. PubMed  Europe PubMed DOI  PMC  EPMC
    8. 2023
  8. Kasal,M.R., Kotamarthi,H.C., Johnson,M.M., Stephens,H.M., Lang,M.J., Sauer,R.T. and Baker,T.A.
    Lon degrades stable substrates slowly but with enhanced processivity, redefining the attributes of a successful AAA+ protease
    Cell Rep (2023) 42, 113061-113061. PubMed  Europe PubMed DOI  PMC  EPMC
  9. Li,S., Hsieh,K.Y., Kuo,C.I., Lin,T.C., Lee,S.H., Chen,Y.R., Wang,C.H., Ho,M.R., Ting,S.Y., Zhang,K. and Chang,C.I.
    A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine
    Nat Commun (2023) 14, 7340-7340. PubMed  Europe PubMed DOI  PMC  EPMC
  10. Omnus,D.J., Fink,M.J., Kallazhi,A., Xandri Zaragoza,M., Leppert,A., Landreh,M. and Jonas,K.
    The heat shock protein LarA activates the Lon protease in response to proteotoxic stress
    Nat Commun (2023) 14, 7636-7636. PubMed  Europe PubMed DOI  PMC  EPMC
  11. Rao,S.N., Kumari,G.M., Srividya,D., Anil,H.S., Lakshmikanth,M., Naik,H. and Prabhuraj,A.
    Validation of Lon Gene Disruption using Linear DNA Cassette by Crelox Mechanism in E. coli Strains: To Achieve Better Solubility of Putrescine Monooxygenase
    Indian J Microbiol (2023) 63, 56-64. PubMed  Europe PubMed DOI  PMC  EPMC
    12. 2022
  12. Niwa,T., Chadani,Y. and Taguchi,H.
    Shotgun Proteomics Revealed Preferential Degradation of Misfolded In Vivo Obligate GroE Substrates by Lon Protease in Escherichia coli
    Molecules (2022) 27 PubMed  Europe PubMed DOI  PMC  EPMC
  13. Olney,S.G., Chien,P. and Kearns,D.B.
    SmiA is a hybrid priming/scaffolding adaptor for the LonA protease in Bacillus subtilis
    J Biol Chem (2022) 298, 102045-102045. PubMed  Europe PubMed DOI  PMC  EPMC
    14. 2021
  14. Butler,D.S.C., Cafaro,C., Putze,J., Wan,M.L.Y., Tran,T.H., Ambite,I., Ahmadi,S., Kjellstrom,S., Welinder,C., Chao,S.M., Dobrindt,U. and Svanborg,C.
    A bacterial protease depletes c-MYC and increases survival in mouse models of bladder and colon cancer
    Nat Biotechnol (2021) PubMed  Europe PubMed DOI
  15. Coscia,F. and Lowe,J.
    Cryo-EM structure of the full-length Lon protease from Thermus thermophilus
    FEBS Lett (2021) PubMed  Europe PubMed DOI
  16. Goo,E. and Hwang,I.
    Essential roles of Lon protease in the morpho-physiological traits of the rice pathogen Burkholderia glumae
    PLoS ONE (2021) 16, e0257257-e0257257. PubMed  Europe PubMed DOI  PMC  EPMC
  17. Li,S., Hsieh,K.Y., Su,S.C., Pintilie,G.D., Zhang,K. and Chang,C.I.
    Molecular basis for ATPase-powered substrate translocation by the Lon AAA+ protease
    J Biol Chem (2021) , 101239-101239. PubMed  Europe PubMed DOI  PMC  EPMC
  18. Springer,K., Sanger,P.A., Felsl,A. and Fuchs,T.M.
    Lon protease- and temperature-dependent activity of a lysis cassette located in the insecticidal island of Yersinia enterocolitica
    J Bacteriol (2021) 203, e00616-20-e00616-20. PubMed  Europe PubMed DOI
  19. Yeom,J. and Groisman,E.A.
    Low cytoplasmic magnesium increases the specificity of the Lon and ClpAP proteases
    J Bacteriol (2021) 203, e0014321-e0014321. PubMed  Europe PubMed DOI
    20. 2020
  20. Muselius,B., Sukumaran,A., Yeung,J. and Geddes-McAlister,J.
    Iron limitation in Klebsiella pneumoniae defines new roles for lon protease in homeostasis and degradation by quantitative proteomics
    Front Microbiol (2020) 11, 546-546. PubMed  Europe PubMed DOI  PMC  EPMC
  21. Thompson,S., Zhang,Y., Ingle,C., Reynolds,K.A. and Kortemme,T.
    Altered expression of a quality control protease in E. coli reshapes the in vivo mutational landscape of a model enzyme
    elife (2020) 9 PubMed  Europe PubMed DOI  PMC  EPMC
    22. 2019
  22. Babin,B.M., Kasperkiewicz,P., Janiszewski,T., Yoo,E., Dra G,M. and Bogyo,M.
    Leveraging peptide substrate libraries to design inhibitors of bacterial Lon protease
    ACS Chem Biol (2019) 14, 2453-2462. PubMed  Europe PubMed DOI  P  I
  23. Brown,B.L., Vieux,E.F., Kalastavadi,T., Kim,S., Chen,J.Z. and Baker,T.A.
    N domain of the Lon AAA+ protease controls assembly and substrate choice
    Protein Sci (2019) 28, 1239-1251. PubMed  Europe PubMed DOI
  24. Chen,X., Zhang,S., Bi,F., Guo,C., Feng,L., Wang,H., Yao,H. and Lin,D.
    Crystal structure of the N domain of Lon protease from Mycobacterium avium complex
    Protein Sci (2019) 28, 1720-1726. PubMed  Europe PubMed DOI  S
  25. Rotanova,T.V., Andrianova,A.G., Kudzhaev,A.M., Li,M., Botos,I., Wlodawer,A. and Gustchina,A.
    New insights into structural and functional relationships between LonA proteases and ClpB chaperones
    FEBS Open Bio (2019) 9, 1536-1551. PubMed  Europe PubMed DOI
  26. Yeom,J. and Groisman,E.A.
    Activator of one protease transforms into inhibitor of another in response to nutritional signals
    Genes Dev (2019) 33, 1280-1292. PubMed  Europe PubMed DOI
    27. 2018
  27. Arends,J., Griego,M., Thomanek,N., Lindemann,C., Kutscher,B., Meyer,H.E. and Narberhaus,F.
    An integrated proteomic approach uncovers novel substrates and functions of the Lon protease in Escherichia coli
    Proteomics (2018) , e1800080-e1800080. PubMed  Europe PubMed DOI
  28. Ching,C., Yang,B., Onwubueke,C., Lazinski,D., Camilli,A. and Godoy,V.G.
    Lon protease has multifaceted biological functions in Acinetobacter baumannii
    J Bacteriol (2018) 201, e00536-18-e00536-18. PubMed  Europe PubMed DOI
  29. He,L., Luo,D., Yang,F., Li,C., Zhang,X., Deng,H. and Zhang,J.R.
    Multiple domains of bacterial and human Lon proteases define substrate selectivity
    Emerg Microbes Infect (2018) 7, 149-149. PubMed  Europe PubMed DOI  PMC  EPMC  P
    30. 2017
  30. Karlowicz,A., Wegrzyn,K., Gross,M., Kaczynska,D., Ropelewska,M., Siemiatkowska,M., Bujnicki,J.M. and Konieczny,I.
    Defining the crucial domain and amino acid residues in bacterial Lon protease for DNA binding and processing of DNA-interacting substrates
    J Biol Chem (2017) 292, 7507-7518. PubMed  Europe PubMed DOI
  31. Kudzhaev,A.M., Andrianova,A.G., Dubovtseva,E.S., Serova,O.V. and Rotanova,T.V.
    Role of the inserted alpha-helical domain in E. coli ATP-dependent Lon protease function
    Acta Naturae (2017) 9, 75-81. PubMed  Europe PubMed  PMC  EPMC
  32. Puri,N. and Karzai,A.W.
    HspQ Functions as a unique specificity-enhancing factor for the AAA+ Lon protease
    Mol Cell (2017) 66, 672-683. PubMed  Europe PubMed DOI
    33. 2016
  33. Bhaskarla,C., Das,M., Verma,T., Kumar,A., Mahadevan,S. and Nandi,D.
    Roles of Lon protease and its substrate MarA during sodium salicylate-mediated growth reduction and antibiotic resistance in Escherichia coli
    Microbiology (Reading) (2016) 162, 764-776. PubMed  Europe PubMed DOI
  34. Fernandez,L., Breidenstein,E.B., Taylor,P.K., Bains,M., de la Fuente-Nunez,C., Fang,Y., Foster,L.J. and Hancock,R.E.
    Interconnection of post-transcriptional regulation: the RNA-binding protein Hfq is a novel target of the Lon protease in Pseudomonas aeruginosa
    Sci Rep (2016) 6, 26811-26811. PubMed  Europe PubMed DOI  PMC  EPMC
  35. Kudzhaev,A.M., Dubovtseva,E.S., Serova,O.V., Andrianova,A.G. and Rotanova,T.V.
    Influence of the (1 - 106) fragment of Escherichia coli Lon protease on the enzyme function and DNA binding
    Russ J Bioorg Chem (2016) 42, 381-388. DOI
  36. Lin,C.C., Su,S.C., Su,M.Y., Liang,P.H., Feng,C.C., Wu,S.H. and Chang,C.I.
    Structural Insights into the Allosteric Operation of the Lon AAA+ Protease
    Structure (2016) 24, 667-675. PubMed  Europe PubMed DOI  S
  37. Su,S.C., Lin,C.C., Tai,H.C., Chang,M.Y., Ho,M.R., Babu,C.S., Liao,J.H., Wu,S.H., Chang,Y.C., Lim,C. and Chang,C.I.
    Structural basis for the magnesium-dependent activation and hexamerization of the Lon AAA+ protease
    Structure (2016) 24, 676-686. PubMed  Europe PubMed DOI  S
  38. Xie,F., Li,G., Zhang,Y., Zhou,L., Liu,S., Liu,S. and Wang,C.
    The Lon protease homologue LonA, not LonC, contributes to the stress tolerance and biofilm formation of Actinobacillus pleuropneumoniae
    Microb Pathog (2016) 93, 38-43. PubMed  Europe PubMed DOI
  39. Yang,N. and Lan,L.
    Pseudomonas aeruginosa Lon and ClpXP proteases: roles in linking carbon catabolite repression system with quorum-sensing system
    Curr Genet (2016) 62, 1-6. PubMed  Europe PubMed DOI
    40. 2015
  40. Cusick,J.K., Hager,E. and Gill,R.E.
    Identification of a mutant locus that bypasses the BsgA protease requirement for social development in Myxococcus xanthus
    FEMS Microbiol Lett (2015) 362, 1-8. PubMed  Europe PubMed DOI
  41. Kudzhaev,A.M., Andrianova,A.G., Serova,O.V., Arkhipova,V.A., Dubovtseva,E.S. and Rotanova,T.V.
    The effect of mutations in the inserted domain of ATP-dependent Lon protease from E. coli on the enzyme function
    Russ J Bioorg Chem (2015) 41, 518-524. DOI
  42. Kudzhaev,A.M., Andrianova,A.G., Serova,O.V., Arkhipova,V.A., Dubovtseva,E.S. and Rotanova,T.V.
    [The effect of mutations in the inserted domain of ATP-dependent Lon protease from E. coli on the enzyme function]
    Bioorg Khim (2015) 41, 579-586. PubMed  Europe PubMed
  43. Mukherjee,S., Bree,A.C., Liu,J., Patrick,J.E., Chien,P. and Kearns,D.B.
    Adaptor-mediated Lon proteolysis restricts Bacillus subtilis hyperflagellation
    Proc Natl Acad Sci U S A (2015) 112, 250-255. PubMed  Europe PubMed DOI
  44. Nishii,W., Kukimoto-Niino,M., Terada,T., Shirouzu,M., Muramatsu,T., Kojima,M., Kihara,H. and Yokoyama,S.
    A redox switch shapes the Lon protease exit pore to facultatively regulate proteolysis
    Nat Chem Biol (2015) 11, 46-51. PubMed  Europe PubMed DOI
  45. Spiridonova,V.A., Kudzhaev,A.M., Melnichuk,A.V., Gainutdinov,A.A., Andrianova,A.G. and Rotanova,T.V.
    [Interaction of DNA aptamers with the ATP-dependent Lon protease from Escherichia coli]
    Bioorg Khim (2015) 41, 696-700. PubMed  Europe PubMed  I
    46. 2014
  46. Andrianova,A.G., Kudzhaev,A.M., Serova,O.V., Dergousova,N.I. and Rotanova,T.V.
    Role of alpha-helical domains in functioning of ATP-dependent Lon protease of Escherichia coli
    Russ J Bioorg Chem (2014) 40, 620-627. DOI
  47. Kereiche,S., Kovacik,L., Pevala,V., Ambro,L., Bellova,J., Kutejova,E. and Raska,I.
    Three-dimensional reconstruction of the S885A mutant of human mitochondrial Lon protease
    Folia Biol (Praha) (2014) 60 Suppl 1, 62-65. PubMed  Europe PubMed  S
  48. Lee,A.Y., Chen,Y.D., Chang,Y.Y., Lin,Y.C., Chang,C.F., Huang,S.J., Wu,S.H. and Hsu,C.H.
    Structural basis for DNA-mediated allosteric regulation facilitated by the AAA+ module of Lon protease
    Acta Crystallogr D Biol Crystallogr (2014) 70, 218-230. PubMed  Europe PubMed DOI
  49. Tu,I.F., Liao,J.H., Yang,F.L., Lin,N.T., Chan,H.L. and Wu,S.H.
    Lon protease affects the RdxA nitroreductase activity and metronidazole susceptibility in Helicobacter pylori
    Helicobacter (2014) 19, 356-366. PubMed  Europe PubMed DOI
  50. Watanabe,R. and Doukyu,N.
    Improvement of organic solvent tolerance by disruption of the lon gene in Escherichia coli
    J Biosci Bioeng (2014) 118, 139-144. PubMed  Europe PubMed DOI
  51. Wohlever,M.L., Baker,T.A. and Sauer,R.T.
    Roles of the N domain of the AAA+ Lon protease in substrate recognition, allosteric regulation and chaperone activity
    Mol Microbiol (2014) 91, 66-78. PubMed  Europe PubMed DOI
    52. 2013
  52. Chen,Y.D., Chang,Y.Y., Wu,S.H. and Hsu,C.H.
    Crystallization and preliminary X-ray diffraction analysis of the alpha subdomain of Lon protease from Brevibacillus thermoruber
    Acta Crystallogr Sect F Struct Biol Cryst Commun (2013) 69, 899-901. PubMed  Europe PubMed DOI  PMC  EPMC  S
  53. Frees,D., Brondsted,L. and Ingmer,H.
    Bacterial proteases and virulence
    Subcell Biochem (2013) 66, 161-192. PubMed  Europe PubMed DOI
  54. Gur,E.
    The Lon AAA+ protease
    Subcell Biochem (2013) 66, 35-51. PubMed  Europe PubMed DOI
  55. Rotanova,T.V., Dergousova,N.I. and Morozkin,A.D.
    [Unique structural organization of ATP-dependent LonA proteases]
    Bioorg Khim (2013) 39, 303-319. PubMed  Europe PubMed DOI
  56. Vieux,E.F., Wohlever,M.L., Chen,J.Z., Sauer,R.T. and Baker,T.A.
    Distinct quaternary structures of the AAA+ Lon protease control substrate degradation
    Proc Natl Acad Sci U S A (2013) 110, E2002-E2008. PubMed  Europe PubMed DOI
  57. Wohlever,M.L., Nager,A.R., Baker,T.A. and Sauer,R.T.
    Engineering fluorescent protein substrates for the AAA+ Lon protease
    Protein Eng Des Sel (2013) 26, 299-305. PubMed  Europe PubMed DOI  A  P
  58. Wohlever,M.L., Baker,T.A. and Sauer,R.T.
    A mutation in the N domain of Escherichia coli Lon stabilizes dodecamers and selectively alters degradation of model substrates
    J Bacteriol (2013) 195, 5622-5628. PubMed  Europe PubMed DOI
    59. 2012
  59. Breidenstein,E.B., Janot,L., Strehmel,J., Fernandez,L., Taylor,P.K., Kukavica-Ibrulj,I., Gellatly,S.L., Levesque,R.C., Overhage,J. and Hancock,R.E.
    The lon protease is essential for full virulence in Pseudomonas aeruginosa
    PLoS ONE (2012) 7, e49123-e49123. PubMed  Europe PubMed DOI  PMC  EPMC
  60. Cheng,I., Mikita,N., Fishovitz,J., Frase,H., Wintrode,P. and Lee,I.
    Identification of a region in the N-terminus of Escherichia coli Lon that affects ATPase, substrate translocation and proteolytic activity
    J Mol Biol (2012) 418, 208-225. PubMed  Europe PubMed DOI
  61. Chung,C.H. and Goldberg,A.L.
    Lon-A peptidase, endopeptidase La
    [ISSN:978-0-12-407742-3] (2012) 3, 3527-3533. DOI
  62. Gerdes,K. and Maisonneuve,E.
    Bacterial persistence and toxin-antitoxin loci
    Annu Rev Microbiol (2012) 66, 103-123. PubMed  Europe PubMed DOI
  63. Gur,E., Vishkautzan,M. and Sauer,R.T.
    Protein unfolding and degradation by the AAA+ lon protease
    Protein Sci (2012) 21, 268-278. PubMed  Europe PubMed DOI
  64. Nakajima,A., Aono,T., Tsukada,S., Siarot,L., Ogawa,T. and Oyaizu,H.
    Lon protease of Azorhizobium caulinodans ORS571 is required for suppression of reb gene expression
    Appl Environ Microbiol (2012) 78, 6251-6261. PubMed  Europe PubMed DOI
    65. 2011
  65. Langklotz,S. and Narberhaus,F.
    The Escherichia coli replication inhibitor CspD is subject to growth-regulated degradation by the Lon protease
    Mol Microbiol (2011) 80, 1313-1325. PubMed  Europe PubMed DOI
  66. Minami,N., Yasuda,T., Ishii,Y., Fujimori,K. and Amano,F.
    Regulatory role of cardiolipin in the activity of an ATP-dependent protease, Lon, from Escherichia coli
    J Biochem (2011) 149, 519-527. PubMed  Europe PubMed DOI
  67. Sauer,R.T. and Baker,T.A.
    AAA+ Proteases: ATP-fueled machines of protein destruction
    Annu Rev Biochem (2011) 80, 587-612. PubMed  Europe PubMed DOI
  68. Yang,H.J., Lee,J.S., Cha,J.Y. and Baik,H.S.
    Negative regulation of pathogenesis in Pseudomonas syringae pv. tabaci 11528 by ATP-dependent lon protease
    Mol Cells (2011) 32, 317-323. PubMed  Europe PubMed DOI
    69. 2010
  69. Bissonnette,S.A., Rivera-Rivera,I., Sauer,R.T. and Baker,T.A.
    The IbpA and IbpB small heat-shock proteins are substrates of the AAA+ Lon protease
    Mol Microbiol (2010) 75, 1539-1549. PubMed  Europe PubMed DOI
  70. Duman,R.E. and Lowe,J.
    Crystal structures of Bacillus subtilis Lon protease
    J Mol Biol (2010) 401, 653-670. PubMed  Europe PubMed DOI  S
  71. Li,M., Gustchina,A., Rasulova,F.S., Melnikov,E.E., Maurizi,M.R., Rotanova,T.V., Dauter,Z. and Wlodawer,A.
    Structure of the N-terminal fragment of Escherichia coli Lon protease
    Acta Crystallogr D Biol Crystallogr (2010) 66, 865-873. PubMed  Europe PubMed DOI  PMC  EPMC  S
  72. Liao,J.H., Lin,Y.C., Hsu,J., Lee,A.Y., Chen,T.A., Hsu,C.H., Chir,J.L., Hua,K.F., Wu,T.H., Hong,L.J., Yen,P.W., Chiou,A. and Wu,S.H.
    Binding and cleavage of E. coli HUbeta by the E. coli Lon protease
    Biophys J (2010) 98, 129-137. PubMed  Europe PubMed DOI  PMC  EPMC  P
  73. Rotanova,T.V. and Melnikov,E.E.
    A novel view on the architecture of the non-catalytic N-terminal region of ATP-dependent LonA proteases
    Biochem Suppl Ser B (Moscow) (2010) 4, 404-408. DOI  S
  74. Thomas,J., Fishovitz,J. and Lee,I.
    Utilization of positional isotope exchange experiments to evaluate reversibility of ATP hydrolysis catalyzed by Escherichia coli Lon protease
    Biochem Cell Biol (2010) 88, 119-128. PubMed  Europe PubMed DOI
    75. 2009
  75. Chir,J.L., Liao,J.H., Lin,Y.C. and Wu,S.H.
    The N-terminal sequence after residue 247 plays an important role in structure and function of Lon protease from Brevibacillus thermoruber WR-249
    Biochem Biophys Res Commun (2009) 382, 762-765. PubMed  Europe PubMed DOI
  76. Ge,Z. and Karzai,A.W.
    Co-evolution of multipartite interactions between an extended tmRNA tag and a robust Lon protease in Mycoplasma
    Mol Microbiol (2009) 74, 1083-1099. PubMed  Europe PubMed DOI
  77. Gur,E. and Sauer,R.T.
    Degrons in protein substrates program the speed and operating efficiency of the AAA+ Lon proteolytic machine
    Proc Natl Acad Sci U S A (2009) 106, 18503-18508. PubMed  Europe PubMed DOI  PMC  EPMC
  78. Ingmer,H. and Brondsted,L.
    Proteases in bacterial pathogenesis
    Res Microbiol (2009) 160, 704-710. PubMed  Europe PubMed DOI  V
  79. Koodathingal,P., Jaffe,N.E., Kraut,D.A., Prakash,S., Fishbain,S., Herman,C. and Matouschek,A.
    ATP-dependent proteases differ substantially in their ability to unfold globular proteins
    J Biol Chem (2009) 284, 18674-18684. PubMed  Europe PubMed DOI  PMC  EPMC
  80. Malik,M., Capecci,J. and Drlica,K.
    Lon protease is essential for paradoxical survival of Escherichia coli exposed to high concentrations of quinolone
    Antimicrobial Agents Chemother (2009) 53, 3103-3105. PubMed  Europe PubMed DOI  PMC  EPMC
  81. Patterson-Ward,J., Tedesco,J., Hudak,J., Fishovitz,J., Becker,J., Frase,H., McNamara,K. and Lee,I.
    Utilization of synthetic peptides to evaluate the importance of substrate interaction at the proteolytic site of Escherichia coli Lon protease
    Biochim Biophys Acta (2009) 1794, 1355-1363. PubMed  Europe PubMed DOI  PMC  EPMC  P
  82. Taylor,N.L. and Millar,A.H.
    Long bugs to short plants - the Lon protease in protein stability and thermotolerance
    New Phytol (2009) 181, 505-508. PubMed  Europe PubMed DOI  V
  83. Van Melderen,L. and Aertsen,A.
    Regulation and quality control by Lon-dependent proteolysis
    Res Microbiol (2009) 160, 645-651. PubMed  Europe PubMed DOI  V
    84. 2008
  84. Clemmer,K.M. and Rather,P.N.
    The Lon protease regulates swarming motility and virulence gene expression in Proteus mirabilis
    J Med Microbiol (2008) 57, 931-937. PubMed  Europe PubMed DOI
  85. Gur,E. and Sauer,R.T.
    Recognition of misfolded proteins by Lon, a AAA(+) protease
    Genes Dev (2008) 22, 2267-2277. PubMed  Europe PubMed DOI  PMC  EPMC
  86. Gur,E. and Sauer,R.T.
    Evolution of the ssrA degradation tag in Mycoplasma: specificity switch to a different protease
    Proc Natl Acad Sci U S A (2008) 105, 16113-16118. PubMed  Europe PubMed DOI  PMC  EPMC
  87. Heuveling,J., Possling,A. and Hengge,R.
    A role for Lon protease in the control of the acid resistance genes of Escherichia coli
    Mol Microbiol (2008) 69, 534-547. PubMed  Europe PubMed DOI
  88. Inobe,T. and Matouschek,A.
    Protein targeting to ATP-dependent proteases
    Curr Opin Struct Biol (2008) 18, 43-51. PubMed  Europe PubMed DOI  PMC  EPMC  V
  89. Lee,I. and Suzuki,C.K.
    Functional mechanics of the ATP-dependent Lon protease - lessons from endogenous protein and synthetic peptide substrates
    Biochim Biophys Acta (2008) 1784, 727-735. PubMed  Europe PubMed DOI  PMC  EPMC  V
  90. Licht,S. and Lee,I.
    Resolving individual steps in the operation of ATP-dependent proteolytic molecular machines: from conformational changes to substrate translocation and processivity
    Biochemistry (2008) 47, 3595-3605. PubMed  Europe PubMed DOI
  91. Luo,S., McNeill,M., Myers,T.G., Hohman,R.J. and Levine,R.L.
    Lon protease promotes survival of Escherichia coli during anaerobic glucose starvation
    Arch Microbiol (2008) 189, 181-185. PubMed  Europe PubMed DOI
  92. Maehara,T., Hoshino,T. and Nakamura,A.
    Characterization of three putative Lon proteases of Thermus thermophilus HB27 and use of their defective mutants as hosts for production of heterologous proteins
    Extremophiles (2008) 12, 285-296. PubMed  Europe PubMed DOI
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