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Literature for peptidase S16.001: Lon-A peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: A Assay, S Structure, T Target, K Knockout, I Inhibitor, P Specificity, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Ambite,I., Wan,M.L.Y., Tran,H.T., Nazari,A., Chaudhuri,A., Krintel,C., Gomes,I., Sabari,S., Ahmadi,S., Carneiro,A.N.B.M., Ishac,R., Haq,F. and Svanborg,C.
    Multitarget mechanism of MYC inhibition by the bacterial lon protease in disease
    Sci Rep15, 6778-6778. PubMed  Europe PubMed DOI
  2. Cragan,M., Puri,N. and Karzai,A.W.
    Substrate Recognition and Cleavage-Site Preferences of Lon Protease
    J Biol Chem108365-108365. PubMed  Europe PubMed DOI
  3. Gibson,S.E.R., Frost,I., Hierons,S.J., Moses,T., Poon,W.C.K., West,S.A. and Cann,M.J.
    Bacteria encode post-mortem protein catabolism that enables altruistic nutrient recycling
    Nat Commun16, 1400-1400. PubMed  Europe PubMed DOI
  4. Wang,H.J., Kuan,Y.E., Ho,M.R. and Chang,C.I.
    Structural basis for the allosteric activation of Lon by the heat shock protein LarA
    Nat Commun16, 2212-2212. PubMed  Europe PubMed DOI
  5. Yigit,K. and Chien,P.
    Lon-dependent proteolysis in oxidative stress responses
    J Bacteriole0000525-e0000525. PubMed  Europe PubMed DOI  V
    6. 2024
  6. Sanyal,S., Kouznetsova,A., Strom,L. and Bjorkegren,C.
    A system for inducible mitochondria-specific protein degradation in vivo
    Nat Commun15, 1454-1454. PubMed  Europe PubMed DOI
    7. 2023
  7. Kasal,M.R., Kotamarthi,H.C., Johnson,M.M., Stephens,H.M., Lang,M.J., Sauer,R.T. and Baker,T.A.
    Lon degrades stable substrates slowly but with enhanced processivity, redefining the attributes of a successful AAA+ protease
    Cell Rep42, 113061-113061. PubMed  Europe PubMed DOI
  8. Li,S., Hsieh,K.Y., Kuo,C.I., Lin,T.C., Lee,S.H., Chen,Y.R., Wang,C.H., Ho,M.R., Ting,S.Y., Zhang,K. and Chang,C.I.
    A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine
    Nat Commun14, 7340-7340. PubMed  Europe PubMed DOI
    9. 2022
  9. Niwa,T., Chadani,Y. and Taguchi,H.
    Shotgun Proteomics Revealed Preferential Degradation of Misfolded In Vivo Obligate GroE Substrates by Lon Protease in Escherichia coli
    Molecules27, PubMed  Europe PubMed DOI
  10. Olney,S.G., Chien,P. and Kearns,D.B.
    SmiA is a hybrid priming/scaffolding adaptor for the LonA protease in Bacillus subtilis
    J Biol Chem298, 102045-102045. PubMed  Europe PubMed DOI
    11. 2021
  11. Butler,D.S.C., Cafaro,C., Putze,J., Wan,M.L.Y., Tran,T.H., Ambite,I., Ahmadi,S., Kjellstrom,S., Welinder,C., Chao,S.M., Dobrindt,U. and Svanborg,C.
    A bacterial protease depletes c-MYC and increases survival in mouse models of bladder and colon cancer
    Nat Biotechnol PubMed  Europe PubMed DOI
  12. Coscia,F. and Lowe,J.
    Cryo-EM structure of the full-length Lon protease from Thermus thermophilus
    FEBS Lett PubMed  Europe PubMed DOI
  13. Goo,E. and Hwang,I.
    Essential roles of Lon protease in the morpho-physiological traits of the rice pathogen Burkholderia glumae
    PLoS ONE16, e0257257-e0257257. PubMed  Europe PubMed DOI
  14. Li,S., Hsieh,K.Y., Su,S.C., Pintilie,G.D., Zhang,K. and Chang,C.I.
    Molecular basis for ATPase-powered substrate translocation by the Lon AAA+ protease
    J Biol Chem101239-101239. PubMed  Europe PubMed DOI
  15. Springer,K., Sanger,P.A., Felsl,A. and Fuchs,T.M.
    Lon protease- and temperature-dependent activity of a lysis cassette located in the insecticidal island of Yersinia enterocolitica
    J Bacteriol203, e00616-20-e00616-20. PubMed  Europe PubMed DOI
  16. Yeom,J. and Groisman,E.A.
    Low cytoplasmic magnesium increases the specificity of the Lon and ClpAP proteases
    J Bacteriol203, e0014321-e0014321. PubMed  Europe PubMed DOI
    17. 2020
  17. Muselius,B., Sukumaran,A., Yeung,J. and Geddes-McAlister,J.
    Iron limitation in Klebsiella pneumoniae defines new roles for lon protease in homeostasis and degradation by quantitative proteomics
    Front Microbiol11, 546-546. PubMed  Europe PubMed DOI
  18. Thompson,S., Zhang,Y., Ingle,C., Reynolds,K.A. and Kortemme,T.
    Altered expression of a quality control protease in E. coli reshapes the in vivo mutational landscape of a model enzyme
    elife9, PubMed  Europe PubMed DOI
    19. 2019
  19. Babin,B.M., Kasperkiewicz,P., Janiszewski,T., Yoo,E., Dra G,M. and Bogyo,M.
    Leveraging peptide substrate libraries to design inhibitors of bacterial Lon protease
    ACS Chem Biol14, 2453-2462. PubMed  Europe PubMed DOI  P  I
  20. Brown,B.L., Vieux,E.F., Kalastavadi,T., Kim,S., Chen,J.Z. and Baker,T.A.
    N domain of the Lon AAA+ protease controls assembly and substrate choice
    Protein Sci28, 1239-1251. PubMed  Europe PubMed DOI
  21. Chen,X., Zhang,S., Bi,F., Guo,C., Feng,L., Wang,H., Yao,H. and Lin,D.
    Crystal structure of the N domain of Lon protease from Mycobacterium avium complex
    Protein Sci28, 1720-1726. PubMed  Europe PubMed DOI  S
  22. Rotanova,T.V., Andrianova,A.G., Kudzhaev,A.M., Li,M., Botos,I., Wlodawer,A. and Gustchina,A.
    New insights into structural and functional relationships between LonA proteases and ClpB chaperones
    FEBS Open Bio9, 1536-1551. PubMed  Europe PubMed DOI
  23. Yeom,J. and Groisman,E.A.
    Activator of one protease transforms into inhibitor of another in response to nutritional signals
    Genes Dev33, 1280-1292. PubMed  Europe PubMed DOI
    24. 2018
  24. Arends,J., Griego,M., Thomanek,N., Lindemann,C., Kutscher,B., Meyer,H.E. and Narberhaus,F.
    An integrated proteomic approach uncovers novel substrates and functions of the Lon protease in Escherichia coli
    Proteomicse1800080-e1800080. PubMed  Europe PubMed DOI
  25. Ching,C., Yang,B., Onwubueke,C., Lazinski,D., Camilli,A. and Godoy,V.G.
    Lon protease has multifaceted biological functions in Acinetobacter baumannii
    J Bacteriol201, e00536-18-e00536-18. PubMed  Europe PubMed DOI
  26. He,L., Luo,D., Yang,F., Li,C., Zhang,X., Deng,H. and Zhang,J.R.
    Multiple domains of bacterial and human Lon proteases define substrate selectivity
    Emerg Microbes Infect7, 149-149. PubMed  Europe PubMed DOI  P
    27. 2017
  27. Karlowicz,A., Wegrzyn,K., Gross,M., Kaczynska,D., Ropelewska,M., Siemiatkowska,M., Bujnicki,J.M. and Konieczny,I.
    Defining the crucial domain and amino acid residues in bacterial Lon protease for DNA binding and processing of DNA-interacting substrates
    J Biol Chem292, 7507-7518. PubMed  Europe PubMed DOI
  28. Kudzhaev,A.M., Andrianova,A.G., Dubovtseva,E.S., Serova,O.V. and Rotanova,T.V.
    Role of the inserted alpha-helical domain in E. coli ATP-dependent Lon protease function
    Acta Naturae9, 75-81. PubMed  Europe PubMed
  29. Puri,N. and Karzai,A.W.
    HspQ Functions as a unique specificity-enhancing factor for the AAA+ Lon protease
    Mol Cell66, 672-683. PubMed  Europe PubMed DOI
    30. 2016
  30. Bhaskarla,C., Das,M., Verma,T., Kumar,A., Mahadevan,S. and Nandi,D.
    Roles of Lon protease and its substrate MarA during sodium salicylate-mediated growth reduction and antibiotic resistance in Escherichia coli
    Microbiology (Reading)162, 764-776. PubMed  Europe PubMed DOI
  31. Fernandez,L., Breidenstein,E.B., Taylor,P.K., Bains,M., de la Fuente-Nunez,C., Fang,Y., Foster,L.J. and Hancock,R.E.
    Interconnection of post-transcriptional regulation: the RNA-binding protein Hfq is a novel target of the Lon protease in Pseudomonas aeruginosa
    Sci Rep6, 26811-26811. PubMed  Europe PubMed DOI
  32. Kudzhaev,A.M., Dubovtseva,E.S., Serova,O.V., Andrianova,A.G. and Rotanova,T.V.
    Influence of the (1 - 106) fragment of Escherichia coli Lon protease on the enzyme function and DNA binding
    Russ J Bioorg Chem42, 381-388. DOI
  33. Lin,C.C., Su,S.C., Su,M.Y., Liang,P.H., Feng,C.C., Wu,S.H. and Chang,C.I.
    Structural Insights into the Allosteric Operation of the Lon AAA+ Protease
    Structure24, 667-675. PubMed  Europe PubMed DOI  S
  34. Su,S.C., Lin,C.C., Tai,H.C., Chang,M.Y., Ho,M.R., Babu,C.S., Liao,J.H., Wu,S.H., Chang,Y.C., Lim,C. and Chang,C.I.
    Structural basis for the magnesium-dependent activation and hexamerization of the Lon AAA+ protease
    Structure24, 676-686. PubMed  Europe PubMed DOI  S
  35. Xie,F., Li,G., Zhang,Y., Zhou,L., Liu,S., Liu,S. and Wang,C.
    The Lon protease homologue LonA, not LonC, contributes to the stress tolerance and biofilm formation of Actinobacillus pleuropneumoniae
    Microb Pathog93, 38-43. PubMed  Europe PubMed DOI
  36. Yang,N. and Lan,L.
    Pseudomonas aeruginosa Lon and ClpXP proteases: roles in linking carbon catabolite repression system with quorum-sensing system
    Curr Genet62, 1-6. PubMed  Europe PubMed DOI
    37. 2015
  37. Cusick,J.K., Hager,E. and Gill,R.E.
    Identification of a mutant locus that bypasses the BsgA protease requirement for social development in Myxococcus xanthus
    FEMS Microbiol Lett362, 1-8. PubMed  Europe PubMed DOI
  38. Kudzhaev,A.M., Andrianova,A.G., Serova,O.V., Arkhipova,V.A., Dubovtseva,E.S. and Rotanova,T.V.
    [The effect of mutations in the inserted domain of ATP-dependent Lon protease from E. coli on the enzyme function]
    Bioorg Khim41, 579-586. PubMed  Europe PubMed
  39. Kudzhaev,A.M., Andrianova,A.G., Serova,O.V., Arkhipova,V.A., Dubovtseva,E.S. and Rotanova,T.V.
    The effect of mutations in the inserted domain of ATP-dependent Lon protease from E. coli on the enzyme function
    Russ J Bioorg Chem41, 518-524. DOI
  40. Mukherjee,S., Bree,A.C., Liu,J., Patrick,J.E., Chien,P. and Kearns,D.B.
    Adaptor-mediated Lon proteolysis restricts Bacillus subtilis hyperflagellation
    Proc Natl Acad Sci U S A112, 250-255. PubMed  Europe PubMed DOI
  41. Nishii,W., Kukimoto-Niino,M., Terada,T., Shirouzu,M., Muramatsu,T., Kojima,M., Kihara,H. and Yokoyama,S.
    A redox switch shapes the Lon protease exit pore to facultatively regulate proteolysis
    Nat Chem Biol11, 46-51. PubMed  Europe PubMed DOI
  42. Spiridonova,V.A., Kudzhaev,A.M., Melnichuk,A.V., Gainutdinov,A.A., Andrianova,A.G. and Rotanova,T.V.
    [Interaction of DNA aptamers with the ATP-dependent Lon protease from Escherichia coli]
    Bioorg Khim41, 696-700. PubMed  Europe PubMed  I
    43. 2014
  43. Andrianova,A.G., Kudzhaev,A.M., Serova,O.V., Dergousova,N.I. and Rotanova,T.V.
    Role of alpha-helical domains in functioning of ATP-dependent Lon protease of Escherichia coli
    Russ J Bioorg Chem40, 620-627. DOI
  44. Kereiche,S., Kovacik,L., Pevala,V., Ambro,L., Bellova,J., Kutejova,E. and Raska,I.
    Three-dimensional reconstruction of the S885A mutant of human mitochondrial Lon protease
    Folia Biol (Praha)60 Suppl 1, 62-65. PubMed  Europe PubMed  S
  45. Lee,A.Y., Chen,Y.D., Chang,Y.Y., Lin,Y.C., Chang,C.F., Huang,S.J., Wu,S.H. and Hsu,C.H.
    Structural basis for DNA-mediated allosteric regulation facilitated by the AAA+ module of Lon protease
    Acta Crystallogr D Biol Crystallogr70, 218-230. PubMed  Europe PubMed DOI
  46. Tu,I.F., Liao,J.H., Yang,F.L., Lin,N.T., Chan,H.L. and Wu,S.H.
    Lon protease affects the RdxA nitroreductase activity and metronidazole susceptibility in Helicobacter pylori
    Helicobacter19, 356-366. PubMed  Europe PubMed DOI
  47. Watanabe,R. and Doukyu,N.
    Improvement of organic solvent tolerance by disruption of the lon gene in Escherichia coli
    J Biosci Bioeng118, 139-144. PubMed  Europe PubMed DOI
  48. Wohlever,M.L., Baker,T.A. and Sauer,R.T.
    Roles of the N domain of the AAA+ Lon protease in substrate recognition, allosteric regulation and chaperone activity
    Mol Microbiol91, 66-78. PubMed  Europe PubMed DOI
    49. 2013
  49. Chen,Y.D., Chang,Y.Y., Wu,S.H. and Hsu,C.H.
    Crystallization and preliminary X-ray diffraction analysis of the alpha subdomain of Lon protease from Brevibacillus thermoruber
    Acta Crystallogr Sect F Struct Biol Cryst Commun69, 899-901. PubMed  Europe PubMed DOI  S
  50. Frees,D., Brondsted,L. and Ingmer,H.
    Bacterial proteases and virulence
    Subcell Biochem66, 161-192. PubMed  Europe PubMed DOI
  51. Gur,E.
    The Lon AAA+ protease
    Subcell Biochem66, 35-51. PubMed  Europe PubMed DOI
  52. Rotanova,T.V., Dergousova,N.I. and Morozkin,A.D.
    [Unique structural organization of ATP-dependent LonA proteases]
    Bioorg Khim39, 303-319. PubMed  Europe PubMed DOI
  53. Vieux,E.F., Wohlever,M.L., Chen,J.Z., Sauer,R.T. and Baker,T.A.
    Distinct quaternary structures of the AAA+ Lon protease control substrate degradation
    Proc Natl Acad Sci U S A110, E2002-E2008. PubMed  Europe PubMed DOI
  54. Wohlever,M.L., Baker,T.A. and Sauer,R.T.
    A mutation in the N domain of Escherichia coli Lon stabilizes dodecamers and selectively alters degradation of model substrates
    J Bacteriol195, 5622-5628. PubMed  Europe PubMed DOI
  55. Wohlever,M.L., Nager,A.R., Baker,T.A. and Sauer,R.T.
    Engineering fluorescent protein substrates for the AAA+ Lon protease
    Protein Eng Des Sel26, 299-305. PubMed  Europe PubMed DOI  A  P
    56. 2012
  56. Breidenstein,E.B., Janot,L., Strehmel,J., Fernandez,L., Taylor,P.K., Kukavica-Ibrulj,I., Gellatly,S.L., Levesque,R.C., Overhage,J. and Hancock,R.E.
    The lon protease is essential for full virulence in Pseudomonas aeruginosa
    PLoS ONE7, e49123-e49123. PubMed  Europe PubMed DOI
  57. Cheng,I., Mikita,N., Fishovitz,J., Frase,H., Wintrode,P. and Lee,I.
    Identification of a region in the N-terminus of Escherichia coli Lon that affects ATPase, substrate translocation and proteolytic activity
    J Mol Biol418, 208-225. PubMed  Europe PubMed DOI
  58. Chung,C.H. and Goldberg,A.L.
    Lon-A peptidase, endopeptidase La
    [ISSN:978-0-12-407742-3]3, 3527-3533. DOI
  59. Gerdes,K. and Maisonneuve,E.
    Bacterial persistence and toxin-antitoxin loci
    Annu Rev Microbiol66, 103-123. PubMed  Europe PubMed DOI
  60. Gur,E., Vishkautzan,M. and Sauer,R.T.
    Protein unfolding and degradation by the AAA+ lon protease
    Protein Sci21, 268-278. PubMed  Europe PubMed DOI
  61. Nakajima,A., Aono,T., Tsukada,S., Siarot,L., Ogawa,T. and Oyaizu,H.
    Lon protease of Azorhizobium caulinodans ORS571 is required for suppression of reb gene expression
    Appl Environ Microbiol78, 6251-6261. PubMed  Europe PubMed DOI
    62. 2011
  62. Langklotz,S. and Narberhaus,F.
    The Escherichia coli replication inhibitor CspD is subject to growth-regulated degradation by the Lon protease
    Mol Microbiol80, 1313-1325. PubMed  Europe PubMed DOI
  63. Minami,N., Yasuda,T., Ishii,Y., Fujimori,K. and Amano,F.
    Regulatory role of cardiolipin in the activity of an ATP-dependent protease, Lon, from Escherichia coli
    J Biochem149, 519-527. PubMed  Europe PubMed DOI
  64. Sauer,R.T. and Baker,T.A.
    AAA+ Proteases: ATP-fueled machines of protein destruction
    Annu Rev Biochem80, 587-612. PubMed  Europe PubMed DOI
  65. Yang,H.J., Lee,J.S., Cha,J.Y. and Baik,H.S.
    Negative regulation of pathogenesis in Pseudomonas syringae pv. tabaci 11528 by ATP-dependent lon protease
    Mol Cells32, 317-323. PubMed  Europe PubMed DOI
    66. 2010
  66. Bissonnette,S.A., Rivera-Rivera,I., Sauer,R.T. and Baker,T.A.
    The IbpA and IbpB small heat-shock proteins are substrates of the AAA+ Lon protease
    Mol Microbiol75, 1539-1549. PubMed  Europe PubMed DOI
  67. Duman,R.E. and Lowe,J.
    Crystal structures of Bacillus subtilis Lon protease
    J Mol Biol401, 653-670. PubMed  Europe PubMed DOI  S
  68. Li,M., Gustchina,A., Rasulova,F.S., Melnikov,E.E., Maurizi,M.R., Rotanova,T.V., Dauter,Z. and Wlodawer,A.
    Structure of the N-terminal fragment of Escherichia coli Lon protease
    Acta Crystallogr D Biol Crystallogr66, 865-873. PubMed  Europe PubMed DOI  S
  69. Liao,J.H., Lin,Y.C., Hsu,J., Lee,A.Y., Chen,T.A., Hsu,C.H., Chir,J.L., Hua,K.F., Wu,T.H., Hong,L.J., Yen,P.W., Chiou,A. and Wu,S.H.
    Binding and cleavage of E. coli HUbeta by the E. coli Lon protease
    Biophys J98, 129-137. PubMed  Europe PubMed DOI  P
  70. Rotanova,T.V. and Melnikov,E.E.
    A novel view on the architecture of the non-catalytic N-terminal region of ATP-dependent LonA proteases
    Biochem Suppl Ser B (Moscow)4, 404-408. DOI  S
  71. Thomas,J., Fishovitz,J. and Lee,I.
    Utilization of positional isotope exchange experiments to evaluate reversibility of ATP hydrolysis catalyzed by Escherichia coli Lon protease
    Biochem Cell Biol88, 119-128. PubMed  Europe PubMed DOI
    72. 2009
  72. Chir,J.L., Liao,J.H., Lin,Y.C. and Wu,S.H.
    The N-terminal sequence after residue 247 plays an important role in structure and function of Lon protease from Brevibacillus thermoruber WR-249
    Biochem Biophys Res Commun382, 762-765. PubMed  Europe PubMed DOI
  73. Ge,Z. and Karzai,A.W.
    Co-evolution of multipartite interactions between an extended tmRNA tag and a robust Lon protease in Mycoplasma
    Mol Microbiol74, 1083-1099. PubMed  Europe PubMed DOI
  74. Gur,E. and Sauer,R.T.
    Degrons in protein substrates program the speed and operating efficiency of the AAA+ Lon proteolytic machine
    Proc Natl Acad Sci U S A106, 18503-18508. PubMed  Europe PubMed DOI
  75. Ingmer,H. and Brondsted,L.
    Proteases in bacterial pathogenesis
    Res Microbiol160, 704-710. PubMed  Europe PubMed DOI  V
  76. Koodathingal,P., Jaffe,N.E., Kraut,D.A., Prakash,S., Fishbain,S., Herman,C. and Matouschek,A.
    ATP-dependent proteases differ substantially in their ability to unfold globular proteins
    J Biol Chem284, 18674-18684. PubMed  Europe PubMed DOI
  77. Malik,M., Capecci,J. and Drlica,K.
    Lon protease is essential for paradoxical survival of Escherichia coli exposed to high concentrations of quinolone
    Antimicrobial Agents Chemother53, 3103-3105. PubMed  Europe PubMed DOI
  78. Patterson-Ward,J., Tedesco,J., Hudak,J., Fishovitz,J., Becker,J., Frase,H., McNamara,K. and Lee,I.
    Utilization of synthetic peptides to evaluate the importance of substrate interaction at the proteolytic site of Escherichia coli Lon protease
    Biochim Biophys Acta1794, 1355-1363. PubMed  Europe PubMed DOI  P
  79. Taylor,N.L. and Millar,A.H.
    Long bugs to short plants - the Lon protease in protein stability and thermotolerance
    New Phytol181, 505-508. PubMed  Europe PubMed DOI  V
  80. Van Melderen,L. and Aertsen,A.
    Regulation and quality control by Lon-dependent proteolysis
    Res Microbiol160, 645-651. PubMed  Europe PubMed DOI  V
    81. 2008
  81. Clemmer,K.M. and Rather,P.N.
    The Lon protease regulates swarming motility and virulence gene expression in Proteus mirabilis
    J Med Microbiol57, 931-937. PubMed  Europe PubMed DOI
  82. Gur,E. and Sauer,R.T.
    Evolution of the ssrA degradation tag in Mycoplasma: specificity switch to a different protease
    Proc Natl Acad Sci U S A105, 16113-16118. PubMed  Europe PubMed DOI
  83. Gur,E. and Sauer,R.T.
    Recognition of misfolded proteins by Lon, a AAA(+) protease
    Genes Dev22, 2267-2277. PubMed  Europe PubMed DOI
  84. Heuveling,J., Possling,A. and Hengge,R.
    A role for Lon protease in the control of the acid resistance genes of Escherichia coli
    Mol Microbiol69, 534-547. PubMed  Europe PubMed DOI
  85. Inobe,T. and Matouschek,A.
    Protein targeting to ATP-dependent proteases
    Curr Opin Struct Biol18, 43-51. PubMed  Europe PubMed DOI  V
  86. Lee,I. and Suzuki,C.K.
    Functional mechanics of the ATP-dependent Lon protease - lessons from endogenous protein and synthetic peptide substrates
    Biochim Biophys Acta1784, 727-735. PubMed  Europe PubMed DOI  V
  87. Licht,S. and Lee,I.
    Resolving individual steps in the operation of ATP-dependent proteolytic molecular machines: from conformational changes to substrate translocation and processivity
    Biochemistry47, 3595-3605. PubMed  Europe PubMed DOI
  88. Luo,S., McNeill,M., Myers,T.G., Hohman,R.J. and Levine,R.L.
    Lon protease promotes survival of Escherichia coli during anaerobic glucose starvation
    Arch Microbiol189, 181-185. PubMed  Europe PubMed DOI
  89. Maehara,T., Hoshino,T. and Nakamura,A.
    Characterization of three putative Lon proteases of Thermus thermophilus HB27 and use of their defective mutants as hosts for production of heterologous proteins
    Extremophiles12, 285-296. PubMed  Europe PubMed DOI
  90. Melnikov,E.E., Andrianova,A.G., Morozkin,A.D., Stepnov,A.A., Makhovskaya,O.V., Botos,I., Gustchina,A., Wlodawer,A. and Rotanova,T.V.
    Limited proteolysis of E. coli ATP-dependent protease Lon - a unified view of the subunit architecture and characterization of isolated enzyme fragments
    Acta Biochim Pol55, 281-296. PubMed  Europe PubMed
  91. Simmons,L.A., Grossman,A.D. and Walker,G.C.
    Clp and Lon proteases occupy distinct subcellular positions in Bacillus subtilis
    J Bacteriol190, 6758-6768. PubMed  Europe PubMed DOI
  92. Takaya,A., Tabuchi,F., Tsuchiya,H., Isogai,E. and Yamamoto,T.
    Negative regulation of quorum-sensing systems in Pseudomonas aeruginosa by ATP-dependent Lon protease
    J Bacteriol190, 4181-4188. PubMed  Europe PubMed DOI
    93. 2007
  93. Bertani,I., Rampioni,G., Leoni,L. and Venturi,V.
    The Pseudomonas putida Lon protease is involved in N-acyl homoserine lactone quorum sensing regulation
    BMC Microbiol7, 71-71. PubMed  Europe PubMed DOI
  94. Brazas,M.D., Breidenstein,E.B., Overhage,J. and Hancock,R.E.
    Role of Lon, an ATP-dependent protease homolog, in resistance of Pseudomonas aeruginosa to ciprofloxacin
    Antimicrob Agents Chemother51, 4276-4283. PubMed  Europe PubMed DOI
  95. Choy,J.S., Aung,L.L. and Karzai,A.W.
    Lon protease degrades transfer-messenger RNA-tagged proteins
    J Bacteriol189, 6564-6571. PubMed  Europe PubMed DOI
  96. Frase,H. and Lee,I.
    Peptidyl boronates inhibit Salmonella enterica serovar Typhimurium Lon protease by a competitive ATP-dependent mechanism
    Biochemistry46, 6647-6657. PubMed  Europe PubMed DOI  I
  97. Patterson-Ward,J., Huang,J. and Lee,I.
    Detection and characterization of two ATP-dependent conformational changes in proteolytically inactive Escherichia coli lon mutants by stopped flow kinetic techniques
    Biochemistry46, 13593-13605. PubMed  Europe PubMed DOI
    98. 2006
  98. [YEAR:11-7-2006]Frase,H., Hudak,J. and Lee,I.
    Identification of the proteasome inhibitor MG262 as a potent ATP-dependent inhibitor of the Salmonella enterica serovar typhimurium Lon protease
    Biochemistry45, 8264-8274. PubMed  Europe PubMed DOI  T  I
  99. Kuroda,A.
    A polyphosphate-Lon protease complex in the adaptation of Escherichia coli to amino acid starvation
    Biosci Biotechnol Biochem70, 325-331. PubMed  Europe PubMed DOI
  100. Lee,I., Berdis,A.J. and Suzuki,C.K.
    Recent developments in the mechanistic enzymology of the ATP-dependent Lon protease from Escherichia coli: highlights from kinetic studies
    Mol Biosyst2, 477-483. PubMed  Europe PubMed DOI  V
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