Merops Switch to
Inhibitors

Peptidase

Family Clan SEARCHES BLAST
MEROPS SUBMISSIONS

Other
information

Literature for family S9

Family

Summary Holotypes Alignment Tree Genomes Structure Literature H-seq M-seq Architecture

S9A

Summary Holotypes Alignment Tree Genomes Literature

S9B

Summary Holotypes Alignment Tree Genomes Literature

S9C

Summary Holotypes Alignment Tree Genomes Literature

S9D

Summary Holotypes Alignment Tree Genomes Literature

(Topics flags: S Structure, T Target, P Specificity, I Inhibitor, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2021
  1. Qian,X.K., Zhang,J., Li,X.D., Song,P.F. and Zou,L.W.
    Research Progress on Dipeptidyl Peptidase Family: Structure, Function and Xenobiotic Metabolism
    Curr Med Chem (2021) PubMed  Europe PubMed DOI  V
    2. 2019
  2. Kiss-Szeman,A.J., Harmat,V. and Menyhard,D.K.
    Achieving functionality through modular build-up: structure and size selection of serine oligopeptidases
    Curr Protein Pept Sci (2019) 20, 1089-1101. PubMed  Europe PubMed DOI
  3. Motta,F.N., Azevedo,C.D.S., Neves,B.P., Araujo,C.N., Grellier,P., Santana,J.M. and Bastos,I.M.D.
    Oligopeptidase B, a missing enzyme in mammals and a potential drug target for trypanosomatid diseases
    Biochimie (2019) 167, 207-216. PubMed  Europe PubMed DOI
  4. Yadav,P., Goyal,V.D., Gaur,N.K., Kumar,A., Gokhale,S.M., Jamdar,S.N. and Makde,R.D.
    Carboxypeptidase in prolyl oligopeptidase family: unique enzyme activation and substrate-screening mechanisms
    J Biol Chem (2019) 294, 89-100. PubMed  Europe PubMed DOI  S
    5. 2018
  5. Iqbal,M., Dubey,M., Gudmundsson,M., Viketoft,M., Jensen,D.F. and Karlsson,M.
    Comparative evolutionary histories of fungal proteases reveal gene gains in the mycoparasitic and nematode-parasitic fungus Clonostachys rosea
    BMC Evol Biol (2018) 18, 171-171. PubMed  Europe PubMed DOI  PMC  EPMC
  6. Luo,H., Cai,Q., Luli,Y., Li,X., Sinha,R., Hallen-Adams,H.E. and Yang,Z.L.
    The MSDIN family in amanitin-producing mushrooms and evolution of the prolyl oligopeptidase genes
    IMA Fungus (2018) 9, 225-242. PubMed  Europe PubMed DOI  PMC  EPMC
    7. 2017
  7. Sato,A. and Ogita,H.
    Pathophysiological implications of dipeptidyl peptidases
    Curr Protein Pept Sci (2017) 18, 843-849. PubMed  Europe PubMed DOI
  8. Vliegen,G., Raju,T.K., Adriaensen,D., Lambeir,A.M. and De Meester,I.
    The expression of proline-specific enzymes in the human lung
    Ann Transl Med (2017) 5, 130-130. PubMed  Europe PubMed DOI  PMC  EPMC
    9. 2016
  9. Wagner,L., Klemann,C., Stephan,M. and von Horsten,S.
    Unravelling the immunological roles of dipeptidyl peptidase 4 (DPP4) activity and/or structure homologue (DASH) proteins
    Clin Exp Immunol (2016) 184, 265-283. PubMed  Europe PubMed DOI
    10. 2015
  10. Waumans,Y., Baerts,L., Kehoe,K., Lambeir,A.M. and De Meester,I.
    The dipeptidyl peptidase family, prolyl oligopeptidase, and prolyl carboxypeptidase in the immune system and inflammatory disease, including atherosclerosis
    Front Immunol (2015) 6, 387-387. PubMed  Europe PubMed DOI  PMC  EPMC
    11. 2010
  11. Yu,D.M., Yao,T.W., Chowdhury,S., Nadvi,N.A., Osborne,B., Church,W.B., McCaughan,G.W. and Gorrell,M.D.
    The dipeptidyl peptidase IV family in cancer and cell biology
    FEBS J (2010) 277, 1126-1144. PubMed  Europe PubMed DOI  V
    12. 2007
  12. Gass,J. and Khosla,C.
    Prolyl endopeptidases
    Cell Mol Life Sci (2007) 64, 345-355. PubMed  Europe PubMed DOI  V  T
    13. 2005
  13. [YEAR:8-12-2005]Gorrell,M.D.
    Dipeptidyl peptidase IV and related enzymes in cell biology and liver disorders
    Clin Sci (Lond) (8-12-2005) 108, 277-292. PubMed  Europe PubMed DOI  V
    14. 2004
  14. [YEAR:13-7-2004]Ajami,K., Abbott,C.A., McCaughan,G.W. and Gorrell,M.D.
    Dipeptidyl peptidase 9 has two forms, a broad tissue distribution, cytoplasmic localization and DPIV-like peptidase activity
    Biochim Biophys Acta (13-7-2004) 1679, 18-28. PubMed  Europe PubMed DOI
  15. Busek,P., Malik,R. and Sedo,A.
    Dipeptidyl peptidase IV activity and/or structure homologues (DASH) and their substrates in cancer
    Int J Biochem Cell Biol (2004) 36, 408-421. PubMed  Europe PubMed DOI
  16. [YEAR:30-7-2004]Kiss,A.L., Szeltner,Z., Fulop,V. and Polgar,L.
    His507 of acylaminoacyl peptidase stabilizes the active site conformation, not the catalytic intermediate
    FEBS Lett (30-7-2004) 571, 17-20. PubMed  Europe PubMed DOI
  17. Venalainen,J.I., Juvonen,R.O. and Mannisto,P.T.
    Evolutionary relationships of the prolyl oligopeptidase family enzymes
    Eur J Biochem (2004) 271, 2705-2715. PubMed  Europe PubMed DOI
    18. 2003
  18. Rosenblum,J.S. and Kozarich,J.W.
    Prolyl peptidases: a serine protease subfamily with high potential for drug discovery
    Curr Opin Chem Biol (2003) 7, 496-504. PubMed  Europe PubMed DOI  T
    19. 2002
  19. Polgar,L.
    The prolyl oligopeptidase family
    Cell Mol Life Sci (2002) 59, 349-362. PubMed  Europe PubMed DOI
    20. 2000
  20. Szeltner,Z., Renner,V. and Polgar,L.
    Substrate- and pH-dependent contribution of oxyanion binding site to the catalysis of prolyl oligopeptidase, a paradigm of the serine oligopeptidase family
    Protein Sci (2000) 9, 353-360. PubMed  Europe PubMed DOI  PMC  EPMC  I
    21. 1997
  21. Kahyaoglu,A., Haghjoo,K., Guo,F., Jordan,F., Kettner,C., Felfoldi,F. and Polgar,L.
    Low barrier hydrogen bond is absent in the catalytic triads in the ground state but is present in a transition-state complex in the prolyl oligopeptidase family of serine proteases
    J Biol Chem (1997) 272, 25547-25554. PubMed  Europe PubMed DOI  I
    22. 1992
  22. Barrett,A.J. and Rawlings,N.D.
    Oligopeptidases, and the emergence of the prolyl oligopeptidase family
    Biol Chem Hoppe Seyler (1992) 373, 353-360. PubMed  Europe PubMed
  23. Polgar,L.
    Structural relationship between lipases and peptidases of the prolyl oligopeptidase family
    FEBS Lett (1992) 311, 281-284. PubMed  Europe PubMed DOI
    24. 1991
  24. Rawlings,N.D., Polgar,L. and Barrett,A.J.
    A new family of serine-type peptidases related to prolyl oligopeptidase
    Biochem J (1991) 279, 907-908. PubMed  Europe PubMed  PMC  EPMC
    25. 1988
  25. Heins,J., Welker,P., Schonlein,C., Born,I., Hartrodt,B., Neubert,K., Tsuru,D. and Barth,A.
    Mechanism of proline-specific proteinases: (I) Substrate specificity of dipeptidyl peptidase IV from pig kidney and proline-specific endopeptidase from Flavobacterium meningosepticum
    Biochim Biophys Acta (1988) 954, 161-169. PubMed  Europe PubMed  P

feedback
Page created 8-September-2023

EMBL-EBI logo

© 2026 EBI
Terms of use