Literature for peptidase S08.129: Tk-subtilisin

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, E Expression. To select only the references relevant to a single topic, click the link above. See explanation.)

    2021
  1. Uehara,R., Dan,N., Amesaka,H., Yoshizawa,T., Koga,Y., Kanaya,S., Takano,K., Matsumura,H. and Tanaka,S.I.<br>Insertion loop-mediated folding propagation governs efficient maturation of hyperthermophilic Tk-subtilisin at high temperatures<br>FEBS Lett (2021) 595, 452-461. PubMed  Europe PubMed DOI
  2. 2020
  3. Bahun,M., Hartman,K. and Poklar Ulrih,N.<br>Periplasmic production of pernisine in Escherichia coli and determinants for its high thermostability<br>Appl Microbiol Biotechnol (2020) PubMed  Europe PubMed DOI
  4. 2019
  5. Snajder,M., Carrillo Rincon,A.F., Magdevska,V., Bahun,M., Kranjc,L., Pas,M., Juntes,P., Petkovic,H. and Poklar Ulrih,N.<br>Extracellular production of the engineered thermostable protease pernisine from Aeropyrum pernix K1 in Streptomyces rimosus<br>Microb Cell Fact (2019) 18, 196-196. PubMed  Europe PubMed DOI  PMC  EPMC  E
  6. 2015
  7. Snajder,M., Mihelic,M., Turk,D. and Ulrih,N.P.<br>Codon optimisation is key for pernisine expression in Escherichia coli<br>PLoS ONE (2015) 10, e0123288-e0123288. PubMed  Europe PubMed DOI  E
  8. 2014
  9. Koga,Y., Tanaka,S., Sakudo,A., Tobiume,M., Aranishi,M., Hirata,A., Takano,K., Ikuta,K. and Kanaya,S.<br>Proteolysis of abnormal prion protein with a thermostable protease from Thermococcus kodakarensis KOD1<br>Appl Microbiol Biotechnol (2014) 98, 2113-2120. PubMed  Europe PubMed DOI
  10. 2013
  11. Hirata,A., Hori,Y., Koga,Y., Okada,J., Sakudo,A., Ikuta,K., Kanaya,S. and Takano,K.<br>Enzymatic activity of a subtilisin homolog, Tk-SP, from Thermococcus kodakarensis in detergents and its ability to degrade the abnormal prion protein<br>BMC Biotechnol (2013) 13, 19-19. PubMed  Europe PubMed DOI
  12. Uehara,R., Ueda,Y., You,D.J., Koga,Y. and Kanaya,S.<br>Accelerated maturation of Tk-subtilisin by a Leu - >Pro mutation at the C-terminus of the propeptide, which reduces the binding of the propeptide to Tk-subtilisin<br>FEBS J (2013) 280, 994-1006. PubMed  Europe PubMed DOI
  13. Yuzaki,K., Sanda,Y., You,D.J., Uehara,R., Koga,Y. and Kanaya,S.<br>Increase in activation rate of Pro-Tk-subtilisin by a single nonpolar-to-polar amino acid substitution at the hydrophobic core of the propeptide domain<br>Protein Sci (2013) 22, 1711-1721. PubMed  Europe PubMed DOI
  14. 2012
  15. Okada,J., Koga,Y., Takano,K. and Kanaya,S.<br>Slow unfolding pathway of hyperthermophilic Tk-RNase H2 examined by pulse proteolysis using the stable protease Tk-subtilisin<br>Biochemistry (2012) 51, 9178-9191. PubMed  Europe PubMed DOI
  16. Sacco,E., Regonesi,M.E. and Vanoni,M.<br>Archaean serine proteases<br>[ISSN:978-0-12-407742-3] (2012) 3, 3224-3233. DOI
  17. Uehara,R., Takeuchi,Y., Tanaka,S., Takano,K., Koga,Y. and Kanaya,S.<br>Requirement of Ca(2+) ions for the hyperthermostability of Tk-subtilisin from Thermococcus kodakarensis<br>Biochemistry (2012) 51, 5369-5378. PubMed  Europe PubMed DOI
  18. Uehara,R., Tanaka,S., Takano,K., Koga,Y. and Kanaya,S.<br>Requirement of insertion sequence IS1 for thermal adaptation of Pro-Tk-subtilisin from hyperthermophilic archaeon<br>Extremophiles (2012) 16, 841-851. PubMed  Europe PubMed DOI
  19. 2011
  20. Sinsereekul,N., Foophow,T., Yamanouchi,M., Koga,Y., Takano,K. and Kanaya,S.<br>An alternative mature form of subtilisin homologue, Tk-SP, from Thermococcus kodakaraensis identified in the presence of Ca2+<br>FEBS J (2011) 278, 1901-1911. PubMed  Europe PubMed DOI
  21. Tanaka,S., Koga,Y., Takano,K. and Kanaya,S.<br>Inhibition of chymotrypsin- and subtilisin-like serine proteases with Tk-serpin from hyperthermophilic archaeon Thermococcus kodakaraensis<br>Biochim Biophys Acta (2011) 1814, 299-307. PubMed  Europe PubMed DOI
  22. 2010
  23. Foophow,T., Tanaka,S.I., Angkawidjaja,C., Koga,Y., Takano,K. and Kanaya,S.<br>Crystal structure of a subtilisin homologue, Tk-SP, from Thermococcus kodakaraensis: requirement of a C-terminal beta-jelly roll domain for hyperstability<br>J Mol Biol (2010) 400, 865-877. PubMed  Europe PubMed DOI  S
  24. 2009
  25. Takeuchi,Y., Tanaka,S., Matsumura,H., Koga,Y., Takano,K. and Kanaya,S.<br>Requirement of a unique Ca(2+)-binding loop for folding of Tk-subtilisin from a hyperthermophilic archaeon<br>Biochemistry (2009) 48, 10637-10643. PubMed  Europe PubMed DOI
  26. Tanaka,S., Matsumura,H., Koga,Y., Takano,K. and Kanaya,S.<br>Identification of the interactions critical for propeptide-catalyzed folding of Tk-subtilisin<br>J Mol Biol (2009) 394, 306-319. PubMed  Europe PubMed DOI
  27. 2008
  28. Tanaka,S., Takeuchi,Y., Matsumura,H., Koga,Y., Takano,K. and Kanaya,S.<br>Crystal structure of Tk-subtilisin folded without propeptide: requirement of propeptide for acceleration of folding<br>FEBS Lett (2008) 582, 3875-3878. PubMed  Europe PubMed DOI  S
  29. 2007
  30. Pulido,M.A., Koga,Y., Takano,K. and Kanaya,S.<br>Directed evolution of Tk-subtilisin from a hyperthermophilic archaeon: identification of a single amino acid substitution responsible for low-temperature adaptation<br>Protein Eng Des Sel (2007) 20, 143-153. PubMed  Europe PubMed DOI
  31. Pulido,M.A., Tanaka,S., Sringiew,C., You,D.J., Matsumura,H., Koga,Y., Takano,K. and Kanaya,S.<br>Requirement of left-handed glycine residue for high stability of the Tk-subtilisin propeptide as revealed by mutational and crystallographic analyses<br>J Mol Biol (2007) 374, 1359-1373. PubMed  Europe PubMed DOI
  32. Tanaka,S., Matsumura,H., Koga,Y., Takano,K. and Kanaya,S.<br>Four new crystal structures of Tk-subtilisin in unautoprocessed, autoprocessed and mature forms: insight into structural changes during maturation<br>J Mol Biol (2007) 372, 1055-1069. PubMed  Europe PubMed DOI  S
  33. Tanaka,S., Saito,K., Chon,H., Matsumura,H., Koga,Y., Takano,K. and Kanaya,S.<br>Crystal structure of unautoprocessed precursor of subtilisin from a hyperthermophilic archaeon: evidence for Ca2+-induced folding<br>J Biol Chem (2007) 282, 8246-8255. PubMed  Europe PubMed DOI  S
  34. 2006
  35. Pulido,M., Saito,K., Tanaka,S., Koga,Y., Morikawa,M., Takano,K. and Kanaya,S.<br>Ca2+-Dependent maturation of subtilisin from a hyperthermophilic archaeon, Thermococcus kodakaraensis: the propeptide Is a potent inhibitor of the mature domain but is not required for its folding<br>Appl Environ Microbiol (2006) 72, 4154-4162. PubMed  Europe PubMed DOI  PMC  EPMC
  36. Tanaka,S., Saito,K., Chon,H., Matsumura,H., Koga,Y., Takano,K. and Kanaya,S.<br>Crystallization and preliminary X-ray diffraction study of an active-site mutant of pro-Tk-subtilisin from a hyperthermophilic archaeon<br>Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 62, 902-905. PubMed  Europe PubMed DOI  PMC  EPMC
  37. 2003
  38. Catara,G., Ruggiero,G., La Cara,F., Digilio,F.A., Capasso,A. and Rossi,M.<br>A novel extracellular subtilisin-like protease from the hyperthermophile Aeropyrum pernix K1: biochemical properties, cloning, and expression<br>Extremophiles (2003) 7, 391-399. PubMed  Europe PubMed DOI
  39. 2001
  40. Kannan,Y., Koga,Y., Inoue,Y., Haruki,M., Takagi,M., Imanaka,T., Morikawa,M. and Kanaya,S.<br>Active subtilisin-like protease from a hyperthermophilic archaeon in a form with a putative prosequence<br>Appl Environ Microbiol (2001) 67, 2445-2452. PubMed  Europe PubMed DOI  PMC  EPMC