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Literature for peptidase S08.034: subtilisin BPN'

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, P Specificity, I Inhibitor, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2022
  1. Ishida,K., Shimizu,M., Wakasugi,A., Matsui,Y., Nakamura,A. and Kojima,S.
    Development of a novel peptide inhibitor of subtilisin BPN'
    FEBS Open Bio12, 2057-2064. PubMed  Europe PubMed DOI  I
    2. 2021
  2. Chen,Y., Toth,E.A., Ruan,B., Choi,E.J., Simmerman,R., Chen,Y., He,Y., Wang,R., Godoy-Ruiz,R., King,H., Custer,G., Travis Gallagher,D., Rozak,D.A., Solomon,M., Muro,S., Weber,D.J., Orban,J., Fuerst,T.R. and Bryan,P.N.
    Engineering subtilisin proteases that specifically degrade active RAS
    Commun Biol4, 299-299. PubMed  Europe PubMed DOI
  3. Weeks,A.M., Byrnes,J.R., Lui,I. and Wells,J.A.
    Mapping proteolytic neo-N termini at the surface of living cells
    Proc Natl Acad Sci U S A118, PubMed  Europe PubMed DOI
    4. 2020
  4. Che,Z., Cao,X., Chen,G. and Liang,Z.
    An effective combination of codon optimization, gene dosage, and process optimization for high-level production of fibrinolytic enzyme in Komagataella phaffii (Pichia pastoris)
    BMC Biotechnol20, 63-63. PubMed  Europe PubMed DOI
    5. 2015
  5. Iqbal,I., Aftab,M.N., Afzal,M., Ur-Rehman,A., Aftab,S., Zafar,A., Ud-Din,Z., Khuharo,A.R., Iqbal,J. and Ul-Haq,I.
    Purification and characterization of cloned alkaline protease gene of Geobacillus stearothermophilus
    J Basic Microbiol55, 160-171. PubMed  Europe PubMed DOI  E
    6. 2012
  6. Graycar,T.P., Bott,R.R., Power,S.D. and Estell,D.A.
    Subtilisins
    [ISSN:978-0-12-407742-3]3, 3148-3155. DOI
    7. 2011
  7. Jo,H.D., Lee,H.A., Jeong,S.J. and Kim,J.H.
    Purification and characterization of a major fibrinolytic enzyme from Bacillus amyloliquefaciens MJ5-41 isolated from meju
    J Microbiol Biotechnol21, 1166-1173. PubMed  Europe PubMed
  8. Niu,Q., Tian,Y., Zhang,L., Xu,X., Niu,X., Xia,Z., Lei,L., Zhang,K.Q. and Huang,X.
    Overexpression of the key virulence proteases Bace16 and Bae16 in Bacillus nematocida B16 to improve its nematocidal activity
    J Mol Microbiol Biotechnol21, 130-137. PubMed  Europe PubMed DOI
    9. 2010
  9. Huang,W., Tian,B.Y., Guo,J., Cai,W.L. and Huang,J.Z.
    Production of an in vitro-derived deletion mutation of Brevibacillus laterosporus by constructing a homology-driven integration vector
    Curr Microbiol61, 401-406. PubMed  Europe PubMed DOI
    10. 2009
  10. Gallagher,T., Ruan,B., London,M., Bryan,M.A. and Bryan,P.N.
    Structure of a switchable subtilisin complexed with a substrate and with the activator azide
    Biochemistry48, 10389-10394. PubMed  Europe PubMed DOI  S
  11. Tian,B., Huang,W., Huang,J., Jiang,X. and Qin,L.
    Investigation of protease-mediated cuticle-degradation of nematodes by using an improved immunofluorescence-localization method
    J Invertebr Pathol101, 143-146. PubMed  Europe PubMed DOI
    12. 2007
  12. Knight,Z.A., Garrison,J.L., Chan,K., King,D.S. and Shokat,K.M.
    A remodelled protease that cleaves phosphotyrosine substrates
    J Am Chem Soc129, 11672-11673. PubMed  Europe PubMed DOI
  13. Lian,L.H., Tian,B.Y., Xiong,R., Zhu,M.Z., Xu,J. and Zhang,K.Q.
    Proteases from Bacillus: a new insight into the mechanism of action for rhizobacterial suppression of nematode populations
    Lett Appl Microbiol45, 262-269. PubMed  Europe PubMed DOI
  14. Niu,Q., Huang,X., Zhang,L., Lian,L., Li,Y., Li,J., Yang,J. and Zhang,K.
    Functional identification of the gene bace16 from nematophagous bacterium Bacillus nematocida
    Appl Microbiol Biotechnol75, 141-148. PubMed  Europe PubMed DOI
  15. Tian,B., Yang,J., Lian,L., Wang,C., Li,N. and Zhang,K.Q.
    Role of an extracellular neutral protease in infection against nematodes by Brevibacillus laterosporus strain G4
    Appl Microbiol Biotechnol74, 372-380. PubMed  Europe PubMed DOI
    16. 2006
  16. Taniguchi,M., Atiwetin,P., Hirai,T., Itoh,M., Harada,S., Hara,S. and Kamei,K.
    Interaction of subtilisin BPN' and recombinant fungal protease inhibitor F from silkworm with substituted P1 site residues
    Biosci Biotechnol Biochem70, 1262-1264. PubMed  Europe PubMed DOI
  17. [YEAR:3-8-2006]Tian,B., Li,N., Lian,L., Liu,J., Yang,J. and Zhang,K.Q.
    Cloning, expression and deletion of the cuticle-degrading protease BLG4 from nematophagous bacterium Brevibacillus laterosporus G4
    Arch Microbiol186, 297-305. PubMed  Europe PubMed DOI
    18. 2005
  18. Huang,X., Tian,B., Niu,Q., Yang,J., Zhang,L. and Zhang,K.
    An extracellular protease from Brevibacillus laterosporus G4 without parasporal crystals can serve as a pathogenic factor in infection of nematodes
    Res Microbiol156, 719-727. PubMed  Europe PubMed DOI
    19. 2004
  19. [YEAR:15-7-2004]Choi,N.S., Chang,K.T., Jae Maeng,P. and Kim,S.H.
    Cloning, expression, and fibrin (ogen)olytic properties of a subtilisin DJ-4 gene from Bacillus sp. DJ-4
    FEMS Microbiol Lett236, 325-331. PubMed  Europe PubMed DOI
  20. Ganz,P.J., Bauer,M.D., Sun,Y., Fieno,A.M., Grant,R.A., Correa,P.E., Laskowski,M., Jr. and Saunders,C.W.
    Stabilized variant of Streptomyces subtilisin inhibitor and its use in stabilizing subtilisin BPN'
    Protein Eng Des Sel17, 333-339. PubMed  Europe PubMed DOI
  21. Graycar,T.P., Ballinger,M.D. and Wells,J.A.
    Subtilisins
    [ISSN:0-12-079610-4]2, 1786-1792.  V
    22. 2003
  22. Day,R.M., Thalhauser,C.J., Sudmeier,J.L., Vincent,M.P., Torchilin,E.V., Sanford,D.G., Bachovchin,C.W. and Bachovchin,W.W.
    Tautomerism, acid-base equilibria, and H-bonding of the six histidines in subtilisin BPN' by NMR
    Protein Sci12, 794-810. PubMed  Europe PubMed DOI
    23. 2002
  23. Almog,O., Gallagher,D.T., Ladner,J.E., Strausberg,S., Alexander,P., Bryan,P. and Gilliland,G.L.
    Structural basis of thermostability. Analysis of stabilizing mutations in subtilisin BPN'
    J Biol Chem277, 27553-27558. PubMed  Europe PubMed DOI  S
    24. 2001
  24. Alexander,P.A., Ruan,B. and Bryan,P.N.
    Cation-dependent stability of subtilisin
    Biochemistry40, 10634-10639. PubMed  Europe PubMed DOI
  25. Kojima,S., Yanai,H. and Miura,K.
    Accelerated refolding of subtilisin BPN' by tertiary-structure-forming mutants of its propeptide
    J Biochem130, 471-474. PubMed  Europe PubMed
    26. 2000
  26. Yokota,M., Tsuda,I. and Tatsumi,N.
    Availability of Nagarse for DNA analysis as a substitute for proteinase K
    J Clin Lab Anal14, 97-100. PubMed  Europe PubMed DOI
    27. 1999
  27. Dinakarpandian,D., Shenoy,B.C., Hilvert,D., McRee,D.E., McTigue,M. and Carey,P.R.
    Electric fields in active sites: substrate switching from null to strong fields in thiol- and selenol-subtilisins
    Biochemistry38, 6659-6667. PubMed  Europe PubMed DOI
    28. 1998
  28. Almog,O., Gallagher,T., Tordova,M., Hoskins,J., Bryan,P. and Gilliland,G.L.
    Crystal structure of calcium-independent subtilisin BPN' with restored thermal stability folded without the prodomain
    Proteins31, 21-32. PubMed  Europe PubMed DOI  S
    29. 1997
  29. Huang,H.W., Chen,W.C., Wu,C.Y., Yu,H.C., Lin,W.Y., Chen,S.T. and Wang,K.T.
    Kinetic studies of the inhibitory effects of propeptides subtilisin BPN' and Carlsberg to bacterial serine proteases
    Protein Eng10, 1227-1233. PubMed  Europe PubMed
    30. 1996
  30. Ballinger,M.D., Tom,J. and Wells,J.A.
    Furilisin: a variant of subtilisin BPN' engineered for cleaving tribasic substrates
    Biochemistry35, 13579-13585. PubMed  Europe PubMed DOI
  31. Gallagher,T., Oliver,J., Bott,R., Betzel,C. and Gilliland,G.L.
    Subtilisin BPN' at 1.6 A resolution: analysis for discrete disorder and comparison of crystal forms
    Acta Crystallogr D Biol Crystallogr52, 1125-1135. PubMed  Europe PubMed DOI  S
    32. 1995
  32. [YEAR:17-10-1995]Ballinger,M.D., Tom,J. and Wells,J.A.
    Designing subtilisin BPN' to cleave substrates containing dibasic residues
    Biochemistry34, 13312-13319. PubMed  Europe PubMed DOI
  33. Gallagher,T., Gilliland,G., Wang,L. and Bryan,P.
    The prosegment-subtilisin BPN' complex: crystal structure of a specific 'foldase'
    Structure3, 907-914. PubMed  Europe PubMed
  34. Genov,N., Filippi,B., Dolashka,P., Wilson,K.S. and Betzel,C.
    Stability of subtilisins and related proteinases (subtilases)
    Int J Pept Protein Res45, 391-400. PubMed  Europe PubMed
  35. Strausberg,S.L., Alexander,P.A., Gallagher,D.T., Gilliland,G.L., Barnett,B.L. and Bryan,P.N.
    Directed evolution of a subtilisin with calcium-independent stability
    Biotechnology (N Y)13, 669-673. PubMed  Europe PubMed
    36. 1994
  36. [YEAR:11-1-1994]Rheinnecker,M., Eder,J., Pandey,P.S. and Fersht,A.R.
    Variants of subtilisin BPN' with altered specificity profiles
    Biochemistry33, 221-225. PubMed  Europe PubMed
    37. 1993
  37. Eder,J., Rheinnecker,M. and Fersht,A.R.
    Folding of subtilisin BPN': role of the pro-sequence
    J Mol Biol233, 293-304. PubMed  Europe PubMed DOI
  38. [YEAR:13-12-1993]Eder,J., Rheinnecker,M. and Fersht,A.R.
    Hydrolysis of small peptide substrates parallels binding of chymotrypsin inhibitor 2 for mutants of subtilisin BPN'
    FEBS Lett335, 349-352. PubMed  Europe PubMed DOI
  39. [YEAR:21-12-1993]Jackson,S.E. and Fersht,A.R.
    Contribution of long-range electrostatic interactions to the stabilization of the catalytic transition state of the serine protease subtilisin BPN'
    Biochemistry32, 13909-13916. PubMed  Europe PubMed  I
  40. Stoffer,B., Frandsen,T.P., Busk,P.K., Schneider,P., Svendsen,I. and Svensson,B.
    Production, purification and characterization of the catalytic domain of glucoamylase from Aspergillus niger
    Biochem J292, 197-202. PubMed  Europe PubMed  P
    41. 1992
  41. [YEAR:1-9-1992]Braxton,S. and Wells,J.A.
    Incorporation of a stabilizing Ca(2+)-binding loop into subtilisin BPN'
    Biochemistry31, 7796-7801. PubMed  Europe PubMed
  42. Bryan,P., Alexander,P., Strausberg,S., Schwarz,F., Lan,W., Gilliland,G. and Gallagher,D.T.
    Energetics of folding subtilisin BPN'
    Biochemistry31, 4937-4945. PubMed  Europe PubMed DOI
  43. Gron,H., Meldal,M. and Breddam,K.
    Extensive comparison of the substrate preferences of two subtilisins as determined with peptide substrates which are based on the principle of intramolecular quenching
    Biochemistry31, 6011-6018. PubMed  Europe PubMed DOI
    44. 1991
  44. [YEAR:25-6-1991]Braxton,S. and Wells,J.A.
    The importance of a distal hydrogen bonding group in stabilizing the transition state in subtilisin BPN'
    J Biol Chem266, 11797-11800. PubMed  Europe PubMed
  45. [YEAR:25-6-1991]Carter,P., Abrahmsen,L. and Wells,J.A.
    Probing the mechanism and improving the rate of substrate-assisted catalysis in subtilisin BPN'
    Biochemistry30, 6142-6148. PubMed  Europe PubMed
  46. Siezen,R.J., de Vos,W.M., Leunissen,J.A. and Dijkstra,B.W.
    Homology modelling and protein engineering strategy of subtilases, the family of subtilisin-like serine proteinases
    Protein Eng4, 719-737. PubMed  Europe PubMed
  47. Takeuchi,Y., Satow,Y., Nakamura,K.T. and Mitsui,Y.
    Refined crystal structure of the complex of subtilisin BPN' and Streptomyces subtilisin inhibitor at 1.8 A resolution
    J Mol Biol221, 309-325. PubMed  Europe PubMed
  48. Takeuchi,Y., Noguchi,S., Satow,Y., Kojima,S., Kumagai,I., Miura,K., Nakamura,K.T. and Mitsui,Y.
    Molecular recognition at the active site of subtilisin BPN': crystallographic studies using genetically engineered proteinaceous inhibitor SSI (Streptomyces subtilisin inhibitor)
    Protein Eng4, 501-508. PubMed  Europe PubMed  S
    49. 1990
  49. Carter,P. and Wells,J.A.
    Functional interaction among catalytic residues in subtilisin BPN'
    Proteins7, 335-342. PubMed  Europe PubMed DOI
  50. Erwin,C.R., Barnett,B.L., Oliver,J.D. and Sullivan,J.F.
    Effects of engineered salt bridges on the stability of subtilisin BPN'
    Protein Eng4, 87-97. PubMed  Europe PubMed  S
    51. 1989
  51. Carter,P., Nilsson,B., Burnier,J.P., Burdick,D. and Wells,J.A.
    Engineering subtilisin BPN' for site-specific proteolysis
    Proteins6, 240-248. PubMed  Europe PubMed DOI
  52. [YEAR:5-9-1989]Pantoliano,M.W., Whitlow,M., Wood,J.F., Dodd,S.W., Hardman,K.D., Rollence,M.L. and Bryan,P.N.
    Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding
    Biochemistry28, 7205-7213. PubMed  Europe PubMed
    53. 1988
  53. [YEAR:5-6-1988]Bott,R., Ultsch,M., Kossiakoff,A., Graycar,T., Katz,B. and Power,S.
    The three-dimensional structure of Bacillus amyloliquefaciens subtilisin at 1.8 A and an analysis of the structural consequences of peroxide inactivation
    J Biol Chem263, 7895-7906. PubMed  Europe PubMed  S
  54. McPhalen,C.A. and James,M.N.
    Structural comparison of two serine proteinase-protein inhibitor complexes: eglin-c-subtilisin Carlsberg and CI-2-subtilisin Novo
    Biochemistry27, 6582-6598. PubMed  Europe PubMed  S
    55. 1987
  55. [YEAR:24-7-1987]Carter,P. and Wells,J.A.
    Engineering enzyme specificity by "substrate-assisted catalysis"
    Science237, 394-399. PubMed  Europe PubMed
    56. 1986
  56. [YEAR:1-2-1986]Bromme,D., Peters,K., Fink,S. and Fittkau,S.
    Enzyme-substrate interactions in the hydrolysis of peptide substrates by thermitase, subtilisin BPN', and proteinase K
    Arch Biochem Biophys244, 439-446. PubMed  Europe PubMed
    57. 1985
  57. Mitsui,Y., Akagawa,H., Onishi,H., Itoh,S., Nakamura,K.T. and Iitaka,Y.
    Crystal structure of subtilisin complexed with its trapped substrate Streptomyces subtilisin inhibitor - protein-protein interaction and evolution of serine proteinases and their proteinaceous inhibitors
    J Biosci8, 481-489. DOI  S
  58. Nedkov,P., Oberthur,W. and Braunitzer,G.
    Determination of the complete amino-acid sequence of subtilisin DY and its comparison with the primary structures of the subtilisins BPN', Carlsberg and amylosacchariticus
    Biol Chem Hoppe Seyler366, 421-430. PubMed  Europe PubMed
    59. 1984
  59. [YEAR:15-9-1984]Hirono,S., Akagawa,H., Mitsui,Y. and Iitaka,Y.
    Crystal structure at 2.6 A resolution of the complex of subtilisin BPN' with streptomyces subtilisin inhibitor
    J Mol Biol178, 389-414. PubMed  Europe PubMed  S
    60. 1983
  60. Wells,J.A., Ferrari,E., Henner,D.J., Estell,D.A. and Chen,E.Y.
    Cloning, sequencing, and secretion of Bacillus amyloliquefaciens subtilisin in Bacillus subtilis
    Nucleic Acids Res11, 7911-7925. PubMed  Europe PubMed
    61. 1977
  61. Priest,F.G.
    Extracellular enzyme synthesis in the genus Bacillus
    Bacteriol Rev41, 711-753. PubMed  Europe PubMed
    62. 1975
  62. [YEAR:25-9-1975]Matthews,D.A., Alden,R.A., Birktoft,J.J., Freer,S.T. and Kraut,J.
    X-ray crystallographic study of boronic acid adducts with subtilisin BPN' (Novo). A model for the catalytic transition state
    J Biol Chem250, 7120-7126. PubMed  Europe PubMed  S  I
    63. 1972
  63. Adams,K.R.
    Investigations on the chemical reactivity of the carboxyl groups in subtilisin type Novo
    C R Trav Lab Carlsberg [Chim]38, 481-498.
  64. [YEAR:27-3-1972]Drenth,J., Hol,W.G., Jansonius,J.N. and Koekoek,R.
    Subtilisin Novo. The three-dimensional structure and its comparison with subtilisin BPN'
    Eur J Biochem26, 177-181. PubMed  Europe PubMed  S
  65. [YEAR:20-6-1972]Robertus,J.D., Alden,R.A., Birktoft,J.J., Kraut,J., Powers,J.C. and Wilcox,P.E.
    An X-ray crystallographic study of the binding of peptide chloromethyl ketone inhibitors to subtilisin BPN'
    Biochemistry11, 2439-2449. PubMed  Europe PubMed  S  I
    66. 1971
  66. Alden,R.A., Birktoft,J.J., Kraut,J., Robertus,J.D. and Wright,C.S.
    Atomic coordinates for subtilisin BPN' (or Novo)
    Biochem Biophys Res Commun45, 337-344. PubMed  Europe PubMed  S
  67. [YEAR:22-1-1971]Robertus,J.D., Alden,R.A. and Kraut,J.
    On the identity of subtilisins BPN' and Novo
    Biochem Biophys Res Commun42, 334-339. PubMed  Europe PubMed
    68. 1970
  68. Morihara,K. and Oka,T.
    Subtilisin BPN': inactivation by chloromethyl ketone derivates of peptide substrates
    Arch Biochem Biophys138, 526-531. PubMed  Europe PubMed
  69. Ottesen,M. and Svendsen,A.
    [11] The subtilisins
    Methods Enzymol19, 199-215. DOI  V
    70. 1969
  70. [YEAR:18-1-1969]Wright,C.S., Alden,R.A. and Kraut,J.
    Structure of subtilisin BPN' at 2.5 angstrom resolution
    Nature221, 235-242. PubMed  Europe PubMed DOI  S
    71. 1966
  71. Smith,E.L., Markland,F.S., Kasper,C.B., DeLange,R.J., Landon,M. and Evans,W.H.
    The complete amino acid sequence of two types of subtilisin, BPN' and Carlsberg
    J Biol Chem241, 5974-5976. PubMed  Europe PubMed
    72. 1960
  72. Sanger,F. and Shaw,D.C.
    Amino-acid sequence about the reactive serine of a proteolytic enzyme from Bacillus subtilis
    Nature187, 872-873. PubMed  Europe PubMed DOI  I
    73. 1956
  73. Okunuki,K., Matsubara,H., Nishimura,S. and Hagihara,B.
    Specificity of crystalline bacterial proteinase
    J Biochem43, 857-866.  P

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