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Literature for peptidase S01.244: kallikrein-related peptidase 8

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: S Structure, A Assay, P Specificity, K Knockout, E Expression, V Review, M Mutation, I Inhibitor, R Splicing. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Bulliard,M., Pinjusic,K., Iacobucci,L., Schmuziger,C., Fournier,N. and Constam,D.B.
    Kallikrein-8 mediates furin-independent Activin-A precursor processing to stimulate tumor growth in melanoma
    Nat Commun16, 2354-2354. PubMed  Europe PubMed DOI  K
    2. 2024
  2. Barman,B. and Thakur,M.K.
    Neuropsin promotes hippocampal synaptogenesis by regulating the expression and cleavage of L1CAM
    J Cell Sci137, PubMed  Europe PubMed DOI  K
  3. Boumali,R., Urli,L., Naim,M., Soualmia,F., Kinugawa,K., Petropoulos,I. and El Amri,C.
    Kallikrein-related peptidase's significance in Alzheimer's disease pathogenesis: A comprehensive survey
    Biochimie226, 77-90. PubMed  Europe PubMed DOI
    4. 2023
  4. Stuardo-Parada,A., Lopez-Munoz,R., Villarroel-Espindola,F., Figueroa,C.D. and Ehrenfeld,P.
    Minireview: functional roles of tissue kallikrein, kinins, and kallikrein-related peptidases in lung cancer
    Med Oncol40, 224-224. PubMed  Europe PubMed DOI  V
  5. Xu,D.H., Du,J.K., Liu,S.Y., Zhang,H., Yang,L., Zhu,X.Y. and Liu,Y.J.
    Upregulation of KLK8 contributes to CUMS-induced hippocampal neuronal apoptosis by cleaving NCAM1
    Cell Death Dis14, 278-278. PubMed  Europe PubMed DOI
    6. 2022
  6. Wagdi,A., Malan,D., Sathyanarayanan,U., Beauchamp,J.S., Vogt,M., Zipf,D., Beiert,T., Mansuroglu,B., Dusend,V., Meininghaus,M., Schneider,L., Kalthof,B., Wiegert,J.S., Konig,G.M., Kostenis,E., Patejdl,R., Sasse,P. and Bruegmann,T.
    Selective optogenetic control of Gq signaling using human Neuropsin
    Nat Commun13, 1765-1765. PubMed  Europe PubMed DOI
    7. 2021
  7. Hua,Q., Sun,Z., Liu,Y., Shen,X., Zhao,W., Zhu,X. and Xu,P.
    KLK8 promotes the proliferation and metastasis of colorectal cancer via the activation of EMT associated with PAR1
    Cell Death Dis12, 860-860. PubMed  Europe PubMed DOI
  8. Jiang,X., Pardue,M.T., Mori,K., Ikeda,S.I., Torii,H., D'Souza,S., Lang,R.A., Kurihara,T. and Tsubota,K.
    Violet light suppresses lens-induced myopia via neuropsin (OPN5) in mice
    Proc Natl Acad Sci U S A118, PubMed  Europe PubMed DOI
  9. Zani,M.B., Sant'Ana,A.M., Tognato,R.C., Chagas,J.R. and Puzer,L.
    Human Tissue Kallikreins-Related Peptidases Are Targets for the Treatment of Skin Desquamation Diseases
    Front Med (Lausanne)8, 777619-777619. PubMed  Europe PubMed DOI  V
    10. 2020
  10. Bukowski,L., Chernomorchenko,A.M.F., Starnawska,A., Mors,O., Staunstrup,N.H., Borglum,A.D. and Qvist,P.
    Neuropsin in mental health
    J Physiol Sci70, 26-26. PubMed  Europe PubMed DOI
  11. Lim,S.C., Kee,K.H., Lee,M.J., Hong,R. and Han,S.I.
    Extracellular acidity induced expression of kallikrein related peptidases 7 and 8 is involved in increased invasiveness of gastric cancer cells
    Oncol Rep43, 1705-1713. PubMed  Europe PubMed DOI
  12. Mella,C., Figueroa,C.D., Otth,C. and Ehrenfeld,P.
    Involvement of Kallikrein-Related Peptidases in Nervous System Disorders
    Front Cell Neurosci14, 166-166. PubMed  Europe PubMed DOI  V
  13. Munster,Y., Keyvani,K. and Herring,A.
    Inhibition of excessive kallikrein-8 improves neuroplasticity in Alzheimer's disease mouse model
    Exp Neurol324, 113115-113115. PubMed  Europe PubMed DOI
  14. Teuber-Hanselmann,S., Rekowski,J., Vogelgsang,J., von Arnim,C., Reetz,K., Stang,A., Jockel,K.H., Wiltfang,J., Esselmann,H., Otto,M., Tumani,H., Herring,A. and Keyvani,K.
    CSF and blood kallikrein-8: a promising early biomarker for Alzheimer's disease
    J Neurol Neurosurg Psychiatry91, 40-48. PubMed  Europe PubMed DOI
    15. 2019
  15. Huang,M., Du,J., Wang,Y., Ma,S., Hu,T., Shang,J., Yu,Q., Zhu,X., Zhang,G. and Cong,B.
    Tissue kallikrein-related peptidase8 protects rat heart against acute ischemia reperfusion injury
    Int J Biol Macromol140, 1126-1133. PubMed  Europe PubMed DOI
  16. Nakazawa,H., Suzuki,Y., Ishikawa,Y., Bando,Y., Yoshida,S. and Shiosaka,S.
    Dataset on the effect of knockout of KLK8 in social memory
    Data Brief26, 104458-104458. PubMed  Europe PubMed DOI
  17. Nakazawa,H., Suzuki,Y., Ishikawa,Y., Bando,Y., Yoshida,S. and Shiosaka,S.
    Impaired social discrimination behavior despite normal social approach by kallikrein-related peptidase 8 knockout mouse
    Neurobiol Learn Mem162, 47-58. PubMed  Europe PubMed DOI
    18. 2018
  18. Debela,M., Magdolen,V., Skala,W., Elsasser,B., Schneider,E.L., Craik,C.S., Biniossek,M.L., Schilling,O., Bode,W., Brandstetter,H. and Goettig,P.
    Structural determinants of specificity and regulation of activity in the allosteric loop network of human KLK8/neuropsin
    Sci Rep8, 10705-10705. PubMed  Europe PubMed DOI  P
  19. Grunberg,M., Quandt,D., Cynis,H., Demuth,H.U., Kindermann,A., Magdolen,V., Forssmann,W.G., Seliger,B. and Magert,H.J.
    Kallikrein-related peptidases are activators of the CC chemokine CCL14
    Eur J Immunol48, 1592-1594. PubMed  Europe PubMed DOI
  20. Konar,A., Kumar,A., Maloney,B., Lahiri,D.K. and Thakur,M.K.
    A serine protease KLK8 emerges as a regulator of regulators in memory: microtubule protein dependent neuronal morphology and PKA-CREB signaling
    Sci Rep8, 9928-9928. PubMed  Europe PubMed DOI
    21. 2017
  21. Adamopoulos,P.G., Kontos,C.K. and Scorilas,A.
    Molecular cloning of novel transcripts of human kallikrein-related peptidases 5, 6, 7, 8 and 9 (KLK5 - KLK9), using Next-generation sequencing
    Sci Rep7, 17299-17299. PubMed  Europe PubMed DOI  M
  22. Hecker,N., Sharma,V. and Hiller,M.
    Transition to an aquatic habitat permitted the repeated loss of the pleiotropic KLK8 gene in mammals
    Genome Biol Evol9, 3179-3188. PubMed  Europe PubMed DOI
  23. Kawata,M., Morikawa,S., Shiosaka,S. and Tamura,H.
    Ablation of neuropsin-neuregulin 1 signaling imbalances ErbB4 inhibitory networks and disrupts hippocampal gamma oscillation
    Transl Psychiatry7, e1052-e1052. PubMed  Europe PubMed DOI
  24. Lahiri,D.K., Konar,A., Thakur,M.K. and Maloney,B.
    A cardinal sin when researching neuropsin/KLK8: Thou shalt validate antibodies
    Alzheimers Dement13, 1068-1069. PubMed  Europe PubMed DOI
    25. 2016
  25. Chang,S., Bok,P., Sun,C.P., Edwards,A. and Huang,G.J.
    Neuropsin inactivation has protective effects against depressive-like behaviours and memory impairment induced by chronic stress
    PLoS Genet12, e1006356-e1006356. PubMed  Europe PubMed DOI  K
  26. Herring,A., Munster,Y., Akkaya,T., Moghaddam,S., Deinsberger,K., Meyer,J., Zahel,J., Sanchez-Mendoza,E., Wang,Y., Hermann,D.M., Arzberger,T., Teuber-Hanselmann,S. and Keyvani,K.
    Kallikrein-8 inhibition attenuates Alzheimer's disease pathology in mice
    Alzheimers Dement12, 1273-1287. PubMed  Europe PubMed DOI
  27. Karakosta,T.D., Soosaipillai,A., Diamandis,E.P., Batruch,I. and Drabovich,A.P.
    Quantification of human kallikrein-related peptidases in biological fluids by multiplatform targeted mass spectrometry assays
    Mol Cell Proteomics15, 2863-2876. PubMed  Europe PubMed DOI  A
    28. 2015
  28. Cerqueira,C., Samperio Ventayol,P., Vogeley,C. and Schelhaas,M.
    Kallikrein-8 proteolytically processes human papillomaviruses in the extracellular space to facilitate entry into host cells
    J Virol89, 7038-7052. PubMed  Europe PubMed DOI
    29. 2014
  29. Azam,S.S. and Raza,S.
    Structure modeling and hybrid virtual screening study of Alzheimer's associated protease kallikrein 8 for the identification of novel inhibitors
    Med Chem Res23, 3516-3527. DOI  I
  30. Sonderegger,P. and Matsumoto-Miyai,K.
    Activity-controlled proteolytic cleavage at the synapse
    Trends Neurosci37, 413-423. PubMed  Europe PubMed DOI
  31. Suzuki,H., Kanagawa,D., Nakazawa,H., Tawara-Hirata,Y., Kogure,Y., Shimizu-Okabe,C., Takayama,C., Ishikawa,Y. and Shiosaka,S.
    Role of neuropsin in parvalbumin immunoreactivity changes in hippocampal basket terminals of mice reared in various environments
    Front Cell Neurosci8, 420-420. PubMed  Europe PubMed DOI
  32. Tawara-Hirata,Y.
    [Neuropsin signaling as a novel therapeutic target of schizophrenia]
    Nihon Yakurigaku Zasshi143, 153-155. PubMed  Europe PubMed DOI
    33. 2013
  33. Lundwall,A.
    Old genes and new genes: The evolution of the kallikrein locus
    Thromb Haemost110, 469-475. PubMed  Europe PubMed DOI  V
    34. 2012
  34. Clements,J.A., Hooper,J.D. and Dong,Y.
    The human tissue kallikrein and kallikrein-related peptidase family
    [ISSN:978-0-12-407742-3]3, 2747-2756. DOI
  35. Eissa,A. and Diamandis,E.P.
    Kallikrein-related peptidase 8
    [ISSN:978-0-12-407742-3]3, 2792-2798. DOI
  36. Tamura,H., Kawata,M., Hamaguchi,S., Ishikawa,Y. and Shiosaka,S.
    Processing of neuregulin-1 by neuropsin regulates GABAergic neuron to control neural plasticity of the mouse hippocampus
    J Neurosci32, 12657-12672. PubMed  Europe PubMed DOI
    37. 2011
  37. Attwood,B.K., Bourgognon,J.M., Patel,S., Mucha,M., Schiavon,E., Skrzypiec,A.E., Young,K.W., Shiosaka,S., Korostynski,M., Piechota,M., Przewlocki,R. and Pawlak,R.
    Neuropsin cleaves EphB2 in the amygdala to control anxiety
    Nature473, 372-375. PubMed  Europe PubMed DOI  K
  38. Eissa,A., Amodeo,V., Smith,C.R. and Diamandis,E.P.
    Kallikrein-related peptidase-8 (KLK8) is an active serine protease in human epidermis and sweat and is involved in a skin barrier proteolytic cascade
    J Biol Chem286, 687-706. PubMed  Europe PubMed DOI
  39. Ishikawa,Y., Tamura,H. and Shiosaka,S.
    Diversity of neuropsin (KLK8)-dependent synaptic associativity in the hippocampal pyramidal neuron
    J Physiol589, 3559-3573. PubMed  Europe PubMed DOI
  40. Shiosaka,S. and Ishikawa,Y.
    Neuropsin - a possible modulator of synaptic plasticity
    J Chem Neuroanat42, 24-29. PubMed  Europe PubMed DOI  K
    41. 2010
  41. Angelopoulou,K. and Karagiannis,G.S.
    Structural characterization and expression of five novel canine kallikrein-related peptidases in mammary cancer
    Mamm Genome21, 516-524. PubMed  Europe PubMed DOI
  42. Shingaki,K., Matsuzaki,S., Taniguchi,M., Kubo,T., Fujiwara,T., Kanazawa,S., Yamamoto,A., Tamura,H., Maeda,T., Ooi,K., Matsumoto,K., Shiosaka,S. and Tohyama,M.
    Molecular mechanism of kallikrein-related peptidase 8/neuropsin-induced hyperkeratosis in inflamed skin
    Br J Dermatol163, 466-475. PubMed  Europe PubMed DOI  K
  43. Yoshida,S.
    Klk8, a multifunctional protease in the brain and skin: analysis of knockout mice
    Biol Chem391, 375-380. PubMed  Europe PubMed DOI  K
    44. 2009
  44. Kountourakis,P., Psyrri,A., Scorilas,A., Markakis,S., Kowalski,D., Camp,R.L., Diamandis,E.P. and Dimopoulos,M.A.
    Expression and prognostic significance of kallikrein-related peptidase 8 protein levels in advanced ovarian cancer by using automated quantitative analysis
    Thromb Haemost101, 541-546. PubMed  Europe PubMed DOI
    45. 2008
  45. Clements,J.A.
    Reflections on the tissue kallikrein and kallikrein-related peptidase family - from mice to men - what have we learnt in the last two decades?
    Biol Chem389, 1447-1454. PubMed  Europe PubMed DOI  V
  46. Horii,Y., Yamasaki,N., Miyakawa,T. and Shiosaka,S.
    Increased anxiety-like behavior in neuropsin (kallikrein-related peptidase 8) gene-deficient mice
    Behav Neurosci122, 498-504. PubMed  Europe PubMed DOI  K
  47. Ishikawa,Y., Horii,Y., Tamura,H. and Shiosaka,S.
    Neuropsin (KLK8)-dependent and -independent synaptic tagging in the Schaffer-collateral pathway of mouse hippocampus
    J Neurosci28, 843-849. PubMed  Europe PubMed DOI
  48. Izumi,A., Iijima,Y., Noguchi,H., Numakawa,T., Okada,T., Hori,H., Kato,T., Tatsumi,M., Kosuga,A., Kamijima,K., Asada,T., Arima,K., Saitoh,O., Shiosaka,S. and Kunugi,H.
    Genetic variations of human neuropsin gene and psychiatric disorders: polymorphism screening and possible association with bipolar disorder and cognitive functions
    Neuropsychopharmacology33, 3237-3245. PubMed  Europe PubMed DOI
  49. Wang,Y., Luo,W. and Reiser,G.
    Trypsin and trypsin-like proteases in the brain: proteolysis and cellular functions
    Cell Mol Life Sci65, 237-252. PubMed  Europe PubMed DOI  V
    50. 2007
  50. Fernando,S.C., Najar,F.Z., Guo,X., Zhou,L., Fu,Y., Geisert,R.D., Roe,B.A. and DeSilva,U.
    Porcine kallikrein gene family: genomic structure, mapping, and differential expression analysis
    Genomics89, 429-438. PubMed  Europe PubMed DOI
  51. Kishibe,M., Bando,Y., Terayama,R., Namikawa,K., Takahashi,H., Hashimoto,Y., Ishida-Yamamoto,A., Jiang,Y.P., Mitrovic,B., Perez,D., Iizuka,H. and Yoshida,S.
    Kallikrein 8 is involved in skin desquamation in cooperation with other kallikreins
    J Biol Chem282, 5834-5841. PubMed  Europe PubMed DOI
  52. Lu,Z.X., Peng,J. and Su,B.
    A human-specific mutation leads to the origin of a novel splice form of neuropsin (KLK8), a gene involved in learning and memory
    Hum Mutat28, 978-984. PubMed  Europe PubMed DOI  M
  53. Scott,F.L., Sun,J., Whisstock,J.C., Kato,K. and Bird,P.I.
    SerpinB6 is an inhibitor of kallikrein-8 in keratinocytes
    J Biochem142, 435-442. PubMed  Europe PubMed DOI
  54. Terayama,R., Bando,Y., Murakami,K., Kato,K., Kishibe,M. and Yoshida,S.
    Neuropsin promotes oligodendrocyte death, demyelination and axonal degeneration after spinal cord injury
    Neuroscience148, 175-187. PubMed  Europe PubMed DOI  K
  55. Weinsheimer,S., Goddard,K.A., Parrado,A.R., Lu,Q., Sinha,M., Lebedeva,E.R., Ronkainen,A., Niemela,M., Khusnutdinova,E.K., Khusainova,R.I., Helin,K., Jaaskelainen,J.E., Sakovich,V.P., Land,S., Kuivaniemi,H. and Tromp,G.
    Association of kallikrein gene polymorphisms with intracranial aneurysms
    Stroke38, 2670-2676. PubMed  Europe PubMed DOI  M
  56. Yoon,H., Laxmikanthan,G., Lee,J., Blaber,S.I., Rodriguez,A., Kogot,J.M., Scarisbrick,I.A. and Blaber,M.
    Activation profiles and regulatory cascades of the human kallikrein-related peptidases
    J Biol Chem282, 31852-31864. PubMed  Europe PubMed DOI  V
    57. 2006
  57. Kishi,T., Cloutier,S.M., Kundig,C., Deperthes,D. and Diamandis,E.P.
    Activation and enzymatic characterization of recombinant human kallikrein 8
    Biol Chem387, 723-731. PubMed  Europe PubMed DOI
  58. Luo,L.Y. and Jiang,W.
    Inhibition profiles of human tissue kallikreins by serine protease inhibitors
    Biol Chem387, 813-816. PubMed  Europe PubMed DOI
  59. [YEAR:1-4-2006]Nakamura,Y., Tamura,H., Horinouchi,K. and Shiosaka,S.
    Role of neuropsin in formation and maturation of Schaffer-collateral L1cam-immunoreactive synaptic boutons
    J Cell Sci119, 1341-1349. PubMed  Europe PubMed DOI
  60. [YEAR:15-12-2006]Sher,Y.P., Chou,C.C., Chou,R.H., Wu,H.M., Wayne Chang,W.S., Chen,C.H., Yang,P.C., Wu,C.W., Yu,C.L. and Peck,K.
    Human kallikrein 8 protease confers a favorable clinical outcome in non-small cell lung cancer by suppressing tumor cell invasiveness
    Cancer Res66, 11763-11770. PubMed  Europe PubMed DOI
  61. [YEAR:24-11-2006]Tamura,H., Ishikawa,Y., Hino,N., Maeda,M., Yoshida,S., Kaku,S. and Shiosaka,S.
    Neuropsin is essential for early processes of memory acquisition and Schaffer collateral long-term potentiation in adult mouse hippocampus in vivo
    J Physiol570, 541-551. PubMed  Europe PubMed DOI
    62. 2005
  62. [YEAR:25-5-2005]Kurlender,L., Borgono,C., Michael,I.P., Obiezu,C., Elliott,M.B., Yousef,G.M. and Diamandis,E.P.
    A survey of alternative transcripts of human tissue kallikrein genes
    Biochim Biophys Acta1755, 1-14. PubMed  Europe PubMed DOI  R
  63. [YEAR:19-12-2005]Rajapakse,S., Ogiwara,K., Takano,N., Moriyama,A. and Takahashi,T.
    Biochemical characterization of human kallikrein 8 and its possible involvement in the degradation of extracellular matrix proteins
    FEBS Lett579, 6879-6884. PubMed  Europe PubMed DOI
  64. [YEAR:26-5-2005]Terayama,R., Bando,Y., Yamada,M. and Yoshida,S.
    Involvement of neuropsin in the pathogenesis of experimental autoimmune encephalomyelitis
    Glia52, 108-118. PubMed  Europe PubMed DOI
    65. 2004
  65. Cane,S., Bignotti,E., Bellone,S., Palmieri,M., De las Casas,L., Roman,J.J., Pecorelli,S., Cannon,M.J., O'Brien,T. and Santin,A.D.
    The novel serine protease tumor-associated differentially expressed gene-14 (KLK8/Neuropsin/Ovasin) is highly overexpressed in cervical cancer
    Am J Obstet Gynecol190, 60-66. PubMed  Europe PubMed DOI
  66. Clements,J.A., Hooper,J.D., Odorico,D.M. and Dong,Y.
    The tissue kallikrein gene cluster
    [ISSN:0-12-079610-4]2, 1569-1577.  V
  67. Kishi,T. and Diamandis,E.P.
    Neuropsin, human tissue kallikrein 8
    [ISSN:0-12-079610-4]2, 1591-1593.  V
  68. [YEAR:28-7-2004]Li,Y., Qian,Y.P., Yu,X.J., Wang,Y.Q., Dong,D.G., Sun,W., Ma,R.M. and Su,B.
    Recent origin of a hominoid-specific splice form of neuropsin, a gene involved in learning and memory
    Mol Biol Evol21, 2111-2115. PubMed  Europe PubMed DOI  R
  69. Shigemasa,K., Tian,X., Gu,L., Tanimoto,H., Underwood,L.J., O'Brien,T.J. and Ohama,K.
    Human kallikrein 8 (hK8/TADG-14) expression is associated with an early clinical stage and favorable prognosis in ovarian cancer
    Oncol Rep11, 1153-1159. PubMed  Europe PubMed
  70. Terayama,R., Bando,Y., Takahashi,T. and Yoshida,S.
    Differential expression of neuropsin and protease M/neurosin in oligodendrocytes after injury to the spinal cord
    Glia48, 91-101. PubMed  Europe PubMed DOI
    71. 2003
  71. Kirihara,T., Matsumoto-Miyai,K., Nakamura,Y., Sadayama,T., Yoshida,S. and Shiosaka,S.
    Prolonged recovery of ultraviolet B-irradiated skin in neuropsin (KLK8)-deficient mice
    Br J Dermatol149, 700-706. PubMed  Europe PubMed DOI  K
  72. Kishi,T., Grass,L., Soosaipillai,A., Shimizu-Okabe,C. and Diamandis,E.P.
    Human kallikrein 8: immunoassay development and identification in tissue extracts and biological fluids
    Clin Chem49, 87-96. PubMed  Europe PubMed DOI  A
  73. [YEAR:1-6-2003]Kishi,T., Grass,L., Soosaipillai,A., Scorilas,A., Harbeck,N., Schmalfeldt,B., Dorn,J., Mysliwiec,M., Schmitt,M. and Diamandis,E.P.
    Human kallikrein 8, a novel biomarker for ovarian carcinoma
    Cancer Res63, 2771-2774. PubMed  Europe PubMed
  74. [YEAR:27-8-2003]Matsumoto-Miyai,K., Ninomiya,A., Yamasaki,H., Tamura,H., Nakamura,Y. and Shiosaka,S.
    NMDA-dependent proteolysis of presynaptic adhesion molecule L1 in the hippocampus by neuropsin
    J Neurosci23, 7727-7736. PubMed  Europe PubMed
  75. [YEAR:28-3-2003]Wong,G.W., Yang,Y., Yasuda,S., Li,L. and Stevens,R.L.
    Mouse mast cells express the tryptic protease neuropsin/Prss19
    Biochem Biophys Res Commun303, 320-325. PubMed  Europe PubMed DOI
  76. [YEAR:1-5-2003]Yousef,G.M., Polymeris,M.E., Yacoub,G.M., Scorilas,A., Soosaipillai,A., Popalis,C., Fracchioli,S., Katsaros,D. and Diamandis,E.P.
    Parallel overexpression of seven kallikrein genes in ovarian cancer
    Cancer Res63, 2223-2227. PubMed  Europe PubMed
    77. 2002
  77. [YEAR:30-9-2002]Katsu,Y., Takasu,E. and Iguchi,T.
    Estrogen-independent expression of neuropsin, a serine protease in the vagina of mice exposed neonatally to diethylstilbestrol
    Mol Cell Endocrinol195, 99-107. PubMed  Europe PubMed DOI
  78. Kuwae,K., Matsumoto-Miyai,K., Yoshida,S., Sadayama,T., Yoshikawa,K., Hosokawa,K. and Shiosaka,S.
    Epidermal expression of serine protease, neuropsin (KLK8) in normal and pathological skin samples
    Mol Pathol55, 235-241. PubMed  Europe PubMed DOI
  79. Matsumoto-Miyai,K., Kitagawa,R., Ninomiya,A., Momota,Y., Yoshida,S. and Shiosaka,S.
    Decidualization induces the expression and activation of an extracellular protease neuropsin in mouse uterus
    Biol Reprod67, 1414-1418. PubMed  Europe PubMed DOI
  80. [YEAR:26-4-2002]Oka,T., Hakoshima,T., Itakura,M., Yamamori,S., Takahashi,M., Hashimoto,Y., Shiosaka,S. and Kato,K.
    Role of loop structures of neuropsin in the activity of serine protease and regulated secretion
    J Biol Chem277, 14724-14730. PubMed  Europe PubMed DOI
  81. [YEAR:22-3-2002]Oka,T., Akisada,M., Okabe,A., Sakurai,K., Shiosaka,S. and Kato,K.
    Extracellular serine protease neuropsin (KLK8) modulates neurite outgrowth and fasciculation of mouse hippocampal neurons in culture
    Neurosci Lett321, 141-144. PubMed  Europe PubMed DOI
    82. 2001
  82. Clements,J., Hooper,J., Dong,Y. and Harvey,T.
    The expanded human kallikrein (KLK) gene family: genomic organisation, tissue-specific expression and potential functions
    Biol Chem382, 5-14. PubMed  Europe PubMed DOI  V
  83. [YEAR:15-9-2001]Davies,B., Kearns,I.R., Ure,J., Davies,C.H. and Lathe,R.
    Loss of hippocampal serine protease BSP1/neuropsin predisposes to global seizure activity
    J Neurosci21, 6993-7000. PubMed  Europe PubMed
  84. He,X.P., Shiosaka,S. and Yoshida,S.
    Expression of neuropsin in oligodendrocytes after injury to the CNS
    Neurosci Res39, 455-462. PubMed  Europe PubMed DOI
  85. Hirata,A., Yoshida,S., Inoue,N., Matsumoto-Miyai,K., Ninomiya,A., Taniguchi,M., Matsuyama,T., Kato,K., Iizasa,H., Kataoka,Y., Yoshida,N. and Shiosaka,S.
    Abnormalities of synapses and neurons in the hippocampus of neuropsin-deficient mice
    Mol Cell Neurosci17, 600-610. PubMed  Europe PubMed DOI  K
  86. [YEAR:4-5-2001]Kato,K., Kishi,T., Kamachi,T., Akisada,M., Oka,T., Midorikawa,R., Takio,K., Dohmae,N., Bird,P.I., Sun,J., Scott,F., Miyake,Y., Yamamoto,K., Machida,A., Tanaka,T., Matsumoto,K., Shibata,M. and Shiosaka,S.
    Serine proteinase inhibitor 3 and murinoglobulin I are potent inhibitors of neuropsin in adult mouse brain
    J Biol Chem276, 14562-14571. PubMed  Europe PubMed DOI
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