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Literature for peptidase S01.244: kallikrein-related peptidase 8

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: S Structure, A Assay, P Specificity, K Knockout, E Expression, V Review, M Mutation, I Inhibitor, R Splicing. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Bulliard,M., Pinjusic,K., Iacobucci,L., Schmuziger,C., Fournier,N. and Constam,D.B.<br>Kallikrein-8 mediates furin-independent Activin-A precursor processing to stimulate tumor growth in melanoma<br>Nat Commun (2025) 16, 2354-2354. PubMed  Europe PubMed DOI  PMC  EPMC  K
  2. Shen,X., Qiao,W., Yan,W., Xie,H., Zhang,C., Sun,Y., Luo,Q. and Xu,Q.<br>Keratinocyte-specific H4K12 lactylation drives a non-canonical IL-17-dependent signaling in psoriasis progression in mice<br>Nat Commun (2025) 16, 8639-8639. PubMed  Europe PubMed DOI  PMC  EPMC
    3. 2024
  3. Barman,B. and Thakur,M.K.<br>Neuropsin promotes hippocampal synaptogenesis by regulating the expression and cleavage of L1CAM<br>J Cell Sci (2024) 137 PubMed  Europe PubMed DOI  K
  4. Boumali,R., Urli,L., Naim,M., Soualmia,F., Kinugawa,K., Petropoulos,I. and El Amri,C.<br>Kallikrein-related peptidase's significance in Alzheimer's disease pathogenesis: A comprehensive survey<br>Biochimie (2024) 226, 77-90. PubMed  Europe PubMed DOI
    5. 2023
  5. Stuardo-Parada,A., Lopez-Munoz,R., Villarroel-Espindola,F., Figueroa,C.D. and Ehrenfeld,P.<br>Minireview: functional roles of tissue kallikrein, kinins, and kallikrein-related peptidases in lung cancer<br>Med Oncol (2023) 40, 224-224. PubMed  Europe PubMed DOI  V
  6. Xu,D.H., Du,J.K., Liu,S.Y., Zhang,H., Yang,L., Zhu,X.Y. and Liu,Y.J.<br>Upregulation of KLK8 contributes to CUMS-induced hippocampal neuronal apoptosis by cleaving NCAM1<br>Cell Death Dis (2023) 14, 278-278. PubMed  Europe PubMed DOI  PMC  EPMC
    7. 2022
  7. Wagdi,A., Malan,D., Sathyanarayanan,U., Beauchamp,J.S., Vogt,M., Zipf,D., Beiert,T., Mansuroglu,B., Dusend,V., Meininghaus,M., Schneider,L., Kalthof,B., Wiegert,J.S., Konig,G.M., Kostenis,E., Patejdl,R., Sasse,P. and Bruegmann,T.<br>Selective optogenetic control of Gq signaling using human Neuropsin<br>Nat Commun (2022) 13, 1765-1765. PubMed  Europe PubMed DOI  PMC  EPMC
    8. 2021
  8. Hua,Q., Sun,Z., Liu,Y., Shen,X., Zhao,W., Zhu,X. and Xu,P.<br>KLK8 promotes the proliferation and metastasis of colorectal cancer via the activation of EMT associated with PAR1<br>Cell Death Dis (2021) 12, 860-860. PubMed  Europe PubMed DOI  PMC  EPMC
  9. Jiang,X., Pardue,M.T., Mori,K., Ikeda,S.I., Torii,H., D'Souza,S., Lang,R.A., Kurihara,T. and Tsubota,K.<br>Violet light suppresses lens-induced myopia via neuropsin (OPN5) in mice<br>Proc Natl Acad Sci U S A (2021) 118 PubMed  Europe PubMed DOI  PMC  EPMC
  10. Zani,M.B., Sant'Ana,A.M., Tognato,R.C., Chagas,J.R. and Puzer,L.<br>Human Tissue Kallikreins-Related Peptidases Are Targets for the Treatment of Skin Desquamation Diseases<br>Front Med (Lausanne) (2021) 8, 777619-777619. PubMed  Europe PubMed DOI  PMC  EPMC  V
    11. 2020
  11. Bukowski,L., Chernomorchenko,A.M.F., Starnawska,A., Mors,O., Staunstrup,N.H., Borglum,A.D. and Qvist,P.<br>Neuropsin in mental health<br>J Physiol Sci (2020) 70, 26-26. PubMed  Europe PubMed DOI
  12. Lim,S.C., Kee,K.H., Lee,M.J., Hong,R. and Han,S.I.<br>Extracellular acidity induced expression of kallikrein related peptidases 7 and 8 is involved in increased invasiveness of gastric cancer cells<br>Oncol Rep (2020) 43, 1705-1713. PubMed  Europe PubMed DOI
  13. Mella,C., Figueroa,C.D., Otth,C. and Ehrenfeld,P.<br>Involvement of Kallikrein-Related Peptidases in Nervous System Disorders<br>Front Cell Neurosci (2020) 14, 166-166. PubMed  Europe PubMed DOI  PMC  EPMC  V
  14. Munster,Y., Keyvani,K. and Herring,A.<br>Inhibition of excessive kallikrein-8 improves neuroplasticity in Alzheimer's disease mouse model<br>Exp Neurol (2020) 324, 113115-113115. PubMed  Europe PubMed DOI
  15. Teuber-Hanselmann,S., Rekowski,J., Vogelgsang,J., von Arnim,C., Reetz,K., Stang,A., Jockel,K.H., Wiltfang,J., Esselmann,H., Otto,M., Tumani,H., Herring,A. and Keyvani,K.<br>CSF and blood kallikrein-8: a promising early biomarker for Alzheimer's disease<br>J Neurol Neurosurg Psychiatry (2020) 91, 40-48. PubMed  Europe PubMed DOI
    16. 2019
  16. Huang,M., Du,J., Wang,Y., Ma,S., Hu,T., Shang,J., Yu,Q., Zhu,X., Zhang,G. and Cong,B.<br>Tissue kallikrein-related peptidase8 protects rat heart against acute ischemia reperfusion injury<br>Int J Biol Macromol (2019) 140, 1126-1133. PubMed  Europe PubMed DOI
  17. Nakazawa,H., Suzuki,Y., Ishikawa,Y., Bando,Y., Yoshida,S. and Shiosaka,S.<br>Impaired social discrimination behavior despite normal social approach by kallikrein-related peptidase 8 knockout mouse<br>Neurobiol Learn Mem (2019) 162, 47-58. PubMed  Europe PubMed DOI
  18. Nakazawa,H., Suzuki,Y., Ishikawa,Y., Bando,Y., Yoshida,S. and Shiosaka,S.<br>Dataset on the effect of knockout of KLK8 in social memory<br>Data Brief (2019) 26, 104458-104458. PubMed  Europe PubMed DOI  PMC  EPMC
    19. 2018
  19. Debela,M., Magdolen,V., Skala,W., Elsasser,B., Schneider,E.L., Craik,C.S., Biniossek,M.L., Schilling,O., Bode,W., Brandstetter,H. and Goettig,P.<br>Structural determinants of specificity and regulation of activity in the allosteric loop network of human KLK8/neuropsin<br>Sci Rep (2018) 8, 10705-10705. PubMed  Europe PubMed DOI  PMC  EPMC  P
  20. Grunberg,M., Quandt,D., Cynis,H., Demuth,H.U., Kindermann,A., Magdolen,V., Forssmann,W.G., Seliger,B. and Magert,H.J.<br>Kallikrein-related peptidases are activators of the CC chemokine CCL14<br>Eur J Immunol (2018) 48, 1592-1594. PubMed  Europe PubMed DOI
  21. Konar,A., Kumar,A., Maloney,B., Lahiri,D.K. and Thakur,M.K.<br>A serine protease KLK8 emerges as a regulator of regulators in memory: microtubule protein dependent neuronal morphology and PKA-CREB signaling<br>Sci Rep (2018) 8, 9928-9928. PubMed  Europe PubMed DOI  PMC  EPMC
    22. 2017
  22. Adamopoulos,P.G., Kontos,C.K. and Scorilas,A.<br>Molecular cloning of novel transcripts of human kallikrein-related peptidases 5, 6, 7, 8 and 9 (KLK5 - KLK9), using Next-generation sequencing<br>Sci Rep (2017) 7, 17299-17299. PubMed  Europe PubMed DOI  PMC  EPMC  M
  23. Hecker,N., Sharma,V. and Hiller,M.<br>Transition to an aquatic habitat permitted the repeated loss of the pleiotropic KLK8 gene in mammals<br>Genome Biol Evol (2017) 9, 3179-3188. PubMed  Europe PubMed DOI
  24. Kawata,M., Morikawa,S., Shiosaka,S. and Tamura,H.<br>Ablation of neuropsin-neuregulin 1 signaling imbalances ErbB4 inhibitory networks and disrupts hippocampal gamma oscillation<br>Transl Psychiatry (2017) 7, e1052-e1052. PubMed  Europe PubMed DOI
  25. Lahiri,D.K., Konar,A., Thakur,M.K. and Maloney,B.<br>A cardinal sin when researching neuropsin/KLK8: Thou shalt validate antibodies<br>Alzheimers Dement (2017) 13, 1068-1069. PubMed  Europe PubMed DOI
    26. 2016
  26. Chang,S., Bok,P., Sun,C.P., Edwards,A. and Huang,G.J.<br>Neuropsin inactivation has protective effects against depressive-like behaviours and memory impairment induced by chronic stress<br>PLoS Genet (2016) 12, e1006356-e1006356. PubMed  Europe PubMed DOI  K
  27. Herring,A., Munster,Y., Akkaya,T., Moghaddam,S., Deinsberger,K., Meyer,J., Zahel,J., Sanchez-Mendoza,E., Wang,Y., Hermann,D.M., Arzberger,T., Teuber-Hanselmann,S. and Keyvani,K.<br>Kallikrein-8 inhibition attenuates Alzheimer's disease pathology in mice<br>Alzheimers Dement (2016) 12, 1273-1287. PubMed  Europe PubMed DOI
  28. Karakosta,T.D., Soosaipillai,A., Diamandis,E.P., Batruch,I. and Drabovich,A.P.<br>Quantification of human kallikrein-related peptidases in biological fluids by multiplatform targeted mass spectrometry assays<br>Mol Cell Proteomics (2016) 15, 2863-2876. PubMed  Europe PubMed DOI  A
    29. 2015
  29. Cerqueira,C., Samperio Ventayol,P., Vogeley,C. and Schelhaas,M.<br>Kallikrein-8 proteolytically processes human papillomaviruses in the extracellular space to facilitate entry into host cells<br>J Virol (2015) 89, 7038-7052. PubMed  Europe PubMed DOI
    30. 2014
  30. Azam,S.S. and Raza,S.<br>Structure modeling and hybrid virtual screening study of Alzheimer's associated protease kallikrein 8 for the identification of novel inhibitors<br>Med Chem Res (2014) 23, 3516-3527. DOI  I
  31. Sonderegger,P. and Matsumoto-Miyai,K.<br>Activity-controlled proteolytic cleavage at the synapse<br>Trends Neurosci (2014) 37, 413-423. PubMed  Europe PubMed DOI
  32. Suzuki,H., Kanagawa,D., Nakazawa,H., Tawara-Hirata,Y., Kogure,Y., Shimizu-Okabe,C., Takayama,C., Ishikawa,Y. and Shiosaka,S.<br>Role of neuropsin in parvalbumin immunoreactivity changes in hippocampal basket terminals of mice reared in various environments<br>Front Cell Neurosci (2014) 8, 420-420. PubMed  Europe PubMed DOI  PMC  EPMC
  33. Tawara-Hirata,Y.<br>[Neuropsin signaling as a novel therapeutic target of schizophrenia]<br>Nihon Yakurigaku Zasshi (2014) 143, 153-155. PubMed  Europe PubMed DOI
    34. 2013
  34. Lundwall,A.<br>Old genes and new genes: The evolution of the kallikrein locus<br>Thromb Haemost (2013) 110, 469-475. PubMed  Europe PubMed DOI  V
    35. 2012
  35. Clements,J.A., Hooper,J.D. and Dong,Y.<br>The human tissue kallikrein and kallikrein-related peptidase family<br>[ISSN:978-0-12-407742-3] (2012) 3, 2747-2756. DOI
  36. Eissa,A. and Diamandis,E.P.<br>Kallikrein-related peptidase 8<br>[ISSN:978-0-12-407742-3] (2012) 3, 2792-2798. DOI
  37. Tamura,H., Kawata,M., Hamaguchi,S., Ishikawa,Y. and Shiosaka,S.<br>Processing of neuregulin-1 by neuropsin regulates GABAergic neuron to control neural plasticity of the mouse hippocampus<br>J Neurosci (2012) 32, 12657-12672. PubMed  Europe PubMed DOI
    38. 2011
  38. Attwood,B.K., Bourgognon,J.M., Patel,S., Mucha,M., Schiavon,E., Skrzypiec,A.E., Young,K.W., Shiosaka,S., Korostynski,M., Piechota,M., Przewlocki,R. and Pawlak,R.<br>Neuropsin cleaves EphB2 in the amygdala to control anxiety<br>Nature (2011) 473, 372-375. PubMed  Europe PubMed DOI  K
  39. Eissa,A., Amodeo,V., Smith,C.R. and Diamandis,E.P.<br>Kallikrein-related peptidase-8 (KLK8) is an active serine protease in human epidermis and sweat and is involved in a skin barrier proteolytic cascade<br>J Biol Chem (2011) 286, 687-706. PubMed  Europe PubMed DOI
  40. Ishikawa,Y., Tamura,H. and Shiosaka,S.<br>Diversity of neuropsin (KLK8)-dependent synaptic associativity in the hippocampal pyramidal neuron<br>J Physiol (2011) 589, 3559-3573. PubMed  Europe PubMed DOI
  41. Shiosaka,S. and Ishikawa,Y.<br>Neuropsin - a possible modulator of synaptic plasticity<br>J Chem Neuroanat (2011) 42, 24-29. PubMed  Europe PubMed DOI  K
    42. 2010
  42. Angelopoulou,K. and Karagiannis,G.S.<br>Structural characterization and expression of five novel canine kallikrein-related peptidases in mammary cancer<br>Mamm Genome (2010) 21, 516-524. PubMed  Europe PubMed DOI
  43. Shingaki,K., Matsuzaki,S., Taniguchi,M., Kubo,T., Fujiwara,T., Kanazawa,S., Yamamoto,A., Tamura,H., Maeda,T., Ooi,K., Matsumoto,K., Shiosaka,S. and Tohyama,M.<br>Molecular mechanism of kallikrein-related peptidase 8/neuropsin-induced hyperkeratosis in inflamed skin<br>Br J Dermatol (2010) 163, 466-475. PubMed  Europe PubMed DOI  K
  44. Yoshida,S.<br>Klk8, a multifunctional protease in the brain and skin: analysis of knockout mice<br>Biol Chem (2010) 391, 375-380. PubMed  Europe PubMed DOI  K
    45. 2009
  45. Kountourakis,P., Psyrri,A., Scorilas,A., Markakis,S., Kowalski,D., Camp,R.L., Diamandis,E.P. and Dimopoulos,M.A.<br>Expression and prognostic significance of kallikrein-related peptidase 8 protein levels in advanced ovarian cancer by using automated quantitative analysis<br>Thromb Haemost (2009) 101, 541-546. PubMed  Europe PubMed DOI
    46. 2008
  46. Clements,J.A.<br>Reflections on the tissue kallikrein and kallikrein-related peptidase family - from mice to men - what have we learnt in the last two decades?<br>Biol Chem (2008) 389, 1447-1454. PubMed  Europe PubMed DOI  V
  47. Horii,Y., Yamasaki,N., Miyakawa,T. and Shiosaka,S.<br>Increased anxiety-like behavior in neuropsin (kallikrein-related peptidase 8) gene-deficient mice<br>Behav Neurosci (2008) 122, 498-504. PubMed  Europe PubMed DOI  K
  48. Ishikawa,Y., Horii,Y., Tamura,H. and Shiosaka,S.<br>Neuropsin (KLK8)-dependent and -independent synaptic tagging in the Schaffer-collateral pathway of mouse hippocampus<br>J Neurosci (2008) 28, 843-849. PubMed  Europe PubMed DOI
  49. Izumi,A., Iijima,Y., Noguchi,H., Numakawa,T., Okada,T., Hori,H., Kato,T., Tatsumi,M., Kosuga,A., Kamijima,K., Asada,T., Arima,K., Saitoh,O., Shiosaka,S. and Kunugi,H.<br>Genetic variations of human neuropsin gene and psychiatric disorders: polymorphism screening and possible association with bipolar disorder and cognitive functions<br>Neuropsychopharmacology (2008) 33, 3237-3245. PubMed  Europe PubMed DOI
  50. Wang,Y., Luo,W. and Reiser,G.<br>Trypsin and trypsin-like proteases in the brain: proteolysis and cellular functions<br>Cell Mol Life Sci (2008) 65, 237-252. PubMed  Europe PubMed DOI  V
    51. 2007
  51. Fernando,S.C., Najar,F.Z., Guo,X., Zhou,L., Fu,Y., Geisert,R.D., Roe,B.A. and DeSilva,U.<br>Porcine kallikrein gene family: genomic structure, mapping, and differential expression analysis<br>Genomics (2007) 89, 429-438. PubMed  Europe PubMed DOI
  52. Kishibe,M., Bando,Y., Terayama,R., Namikawa,K., Takahashi,H., Hashimoto,Y., Ishida-Yamamoto,A., Jiang,Y.P., Mitrovic,B., Perez,D., Iizuka,H. and Yoshida,S.<br>Kallikrein 8 is involved in skin desquamation in cooperation with other kallikreins<br>J Biol Chem (2007) 282, 5834-5841. PubMed  Europe PubMed DOI
  53. Lu,Z.X., Peng,J. and Su,B.<br>A human-specific mutation leads to the origin of a novel splice form of neuropsin (KLK8), a gene involved in learning and memory<br>Hum Mutat (2007) 28, 978-984. PubMed  Europe PubMed DOI  M
  54. Scott,F.L., Sun,J., Whisstock,J.C., Kato,K. and Bird,P.I.<br>SerpinB6 is an inhibitor of kallikrein-8 in keratinocytes<br>J Biochem (2007) 142, 435-442. PubMed  Europe PubMed DOI
  55. Terayama,R., Bando,Y., Murakami,K., Kato,K., Kishibe,M. and Yoshida,S.<br>Neuropsin promotes oligodendrocyte death, demyelination and axonal degeneration after spinal cord injury<br>Neuroscience (2007) 148, 175-187. PubMed  Europe PubMed DOI  K
  56. Weinsheimer,S., Goddard,K.A., Parrado,A.R., Lu,Q., Sinha,M., Lebedeva,E.R., Ronkainen,A., Niemela,M., Khusnutdinova,E.K., Khusainova,R.I., Helin,K., Jaaskelainen,J.E., Sakovich,V.P., Land,S., Kuivaniemi,H. and Tromp,G.<br>Association of kallikrein gene polymorphisms with intracranial aneurysms<br>Stroke (2007) 38, 2670-2676. PubMed  Europe PubMed DOI  M
  57. Yoon,H., Laxmikanthan,G., Lee,J., Blaber,S.I., Rodriguez,A., Kogot,J.M., Scarisbrick,I.A. and Blaber,M.<br>Activation profiles and regulatory cascades of the human kallikrein-related peptidases<br>J Biol Chem (2007) 282, 31852-31864. PubMed  Europe PubMed DOI  V
    58. 2006
  58. Kishi,T., Cloutier,S.M., Kundig,C., Deperthes,D. and Diamandis,E.P.<br>Activation and enzymatic characterization of recombinant human kallikrein 8<br>Biol Chem (2006) 387, 723-731. PubMed  Europe PubMed DOI
  59. Luo,L.Y. and Jiang,W.<br>Inhibition profiles of human tissue kallikreins by serine protease inhibitors<br>Biol Chem (2006) 387, 813-816. PubMed  Europe PubMed DOI
  60. [YEAR:1-4-2006]Nakamura,Y., Tamura,H., Horinouchi,K. and Shiosaka,S.<br>Role of neuropsin in formation and maturation of Schaffer-collateral L1cam-immunoreactive synaptic boutons<br>J Cell Sci (1-4-2006) 119, 1341-1349. PubMed  Europe PubMed DOI
  61. [YEAR:15-12-2006]Sher,Y.P., Chou,C.C., Chou,R.H., Wu,H.M., Wayne Chang,W.S., Chen,C.H., Yang,P.C., Wu,C.W., Yu,C.L. and Peck,K.<br>Human kallikrein 8 protease confers a favorable clinical outcome in non-small cell lung cancer by suppressing tumor cell invasiveness<br>Cancer Res (15-12-2006) 66, 11763-11770. PubMed  Europe PubMed DOI
  62. [YEAR:24-11-2006]Tamura,H., Ishikawa,Y., Hino,N., Maeda,M., Yoshida,S., Kaku,S. and Shiosaka,S.<br>Neuropsin is essential for early processes of memory acquisition and Schaffer collateral long-term potentiation in adult mouse hippocampus in vivo<br>J Physiol (24-11-2006) 570, 541-551. PubMed  Europe PubMed DOI  PMC  EPMC
    63. 2005
  63. [YEAR:25-5-2005]Kurlender,L., Borgono,C., Michael,I.P., Obiezu,C., Elliott,M.B., Yousef,G.M. and Diamandis,E.P.<br>A survey of alternative transcripts of human tissue kallikrein genes<br>Biochim Biophys Acta (25-5-2005) 1755, 1-14. PubMed  Europe PubMed DOI  R
  64. [YEAR:19-12-2005]Rajapakse,S., Ogiwara,K., Takano,N., Moriyama,A. and Takahashi,T.<br>Biochemical characterization of human kallikrein 8 and its possible involvement in the degradation of extracellular matrix proteins<br>FEBS Lett (19-12-2005) 579, 6879-6884. PubMed  Europe PubMed DOI
  65. [YEAR:26-5-2005]Terayama,R., Bando,Y., Yamada,M. and Yoshida,S.<br>Involvement of neuropsin in the pathogenesis of experimental autoimmune encephalomyelitis<br>Glia (26-5-2005) 52, 108-118. PubMed  Europe PubMed DOI
    66. 2004
  66. Cane,S., Bignotti,E., Bellone,S., Palmieri,M., De las Casas,L., Roman,J.J., Pecorelli,S., Cannon,M.J., O'Brien,T. and Santin,A.D.<br>The novel serine protease tumor-associated differentially expressed gene-14 (KLK8/Neuropsin/Ovasin) is highly overexpressed in cervical cancer<br>Am J Obstet Gynecol (2004) 190, 60-66. PubMed  Europe PubMed DOI
  67. Clements,J.A., Hooper,J.D., Odorico,D.M. and Dong,Y.<br>The tissue kallikrein gene cluster<br>[ISSN:0-12-079610-4] (2004) 2, 1569-1577.  V
  68. Kishi,T. and Diamandis,E.P.<br>Neuropsin, human tissue kallikrein 8<br>[ISSN:0-12-079610-4] (2004) 2, 1591-1593.  V
  69. [YEAR:28-7-2004]Li,Y., Qian,Y.P., Yu,X.J., Wang,Y.Q., Dong,D.G., Sun,W., Ma,R.M. and Su,B.<br>Recent origin of a hominoid-specific splice form of neuropsin, a gene involved in learning and memory<br>Mol Biol Evol (28-7-2004) 21, 2111-2115. PubMed  Europe PubMed DOI  R
  70. Shigemasa,K., Tian,X., Gu,L., Tanimoto,H., Underwood,L.J., O'Brien,T.J. and Ohama,K.<br>Human kallikrein 8 (hK8/TADG-14) expression is associated with an early clinical stage and favorable prognosis in ovarian cancer<br>Oncol Rep (2004) 11, 1153-1159. PubMed  Europe PubMed
  71. Terayama,R., Bando,Y., Takahashi,T. and Yoshida,S.<br>Differential expression of neuropsin and protease M/neurosin in oligodendrocytes after injury to the spinal cord<br>Glia (2004) 48, 91-101. PubMed  Europe PubMed DOI
    72. 2003
  72. Kirihara,T., Matsumoto-Miyai,K., Nakamura,Y., Sadayama,T., Yoshida,S. and Shiosaka,S.<br>Prolonged recovery of ultraviolet B-irradiated skin in neuropsin (KLK8)-deficient mice<br>Br J Dermatol (2003) 149, 700-706. PubMed  Europe PubMed DOI  K
  73. [YEAR:1-6-2003]Kishi,T., Grass,L., Soosaipillai,A., Scorilas,A., Harbeck,N., Schmalfeldt,B., Dorn,J., Mysliwiec,M., Schmitt,M. and Diamandis,E.P.<br>Human kallikrein 8, a novel biomarker for ovarian carcinoma<br>Cancer Res (1-6-2003) 63, 2771-2774. PubMed  Europe PubMed
  74. Kishi,T., Grass,L., Soosaipillai,A., Shimizu-Okabe,C. and Diamandis,E.P.<br>Human kallikrein 8: immunoassay development and identification in tissue extracts and biological fluids<br>Clin Chem (2003) 49, 87-96. PubMed  Europe PubMed DOI  A
  75. [YEAR:27-8-2003]Matsumoto-Miyai,K., Ninomiya,A., Yamasaki,H., Tamura,H., Nakamura,Y. and Shiosaka,S.<br>NMDA-dependent proteolysis of presynaptic adhesion molecule L1 in the hippocampus by neuropsin<br>J Neurosci (27-8-2003) 23, 7727-7736. PubMed  Europe PubMed
  76. [YEAR:28-3-2003]Wong,G.W., Yang,Y., Yasuda,S., Li,L. and Stevens,R.L.<br>Mouse mast cells express the tryptic protease neuropsin/Prss19<br>Biochem Biophys Res Commun (28-3-2003) 303, 320-325. PubMed  Europe PubMed DOI
  77. [YEAR:1-5-2003]Yousef,G.M., Polymeris,M.E., Yacoub,G.M., Scorilas,A., Soosaipillai,A., Popalis,C., Fracchioli,S., Katsaros,D. and Diamandis,E.P.<br>Parallel overexpression of seven kallikrein genes in ovarian cancer<br>Cancer Res (1-5-2003) 63, 2223-2227. PubMed  Europe PubMed
    78. 2002
  78. [YEAR:30-9-2002]Katsu,Y., Takasu,E. and Iguchi,T.<br>Estrogen-independent expression of neuropsin, a serine protease in the vagina of mice exposed neonatally to diethylstilbestrol<br>Mol Cell Endocrinol (30-9-2002) 195, 99-107. PubMed  Europe PubMed DOI
  79. Kuwae,K., Matsumoto-Miyai,K., Yoshida,S., Sadayama,T., Yoshikawa,K., Hosokawa,K. and Shiosaka,S.<br>Epidermal expression of serine protease, neuropsin (KLK8) in normal and pathological skin samples<br>Mol Pathol (2002) 55, 235-241. PubMed  Europe PubMed DOI  PMC  EPMC
  80. Matsumoto-Miyai,K., Kitagawa,R., Ninomiya,A., Momota,Y., Yoshida,S. and Shiosaka,S.<br>Decidualization induces the expression and activation of an extracellular protease neuropsin in mouse uterus<br>Biol Reprod (2002) 67, 1414-1418. PubMed  Europe PubMed DOI
  81. [YEAR:26-4-2002]Oka,T., Hakoshima,T., Itakura,M., Yamamori,S., Takahashi,M., Hashimoto,Y., Shiosaka,S. and Kato,K.<br>Role of loop structures of neuropsin in the activity of serine protease and regulated secretion<br>J Biol Chem (26-4-2002) 277, 14724-14730. PubMed  Europe PubMed DOI
  82. [YEAR:22-3-2002]Oka,T., Akisada,M., Okabe,A., Sakurai,K., Shiosaka,S. and Kato,K.<br>Extracellular serine protease neuropsin (KLK8) modulates neurite outgrowth and fasciculation of mouse hippocampal neurons in culture<br>Neurosci Lett (22-3-2002) 321, 141-144. PubMed  Europe PubMed DOI
    83. 2001
  83. Clements,J., Hooper,J., Dong,Y. and Harvey,T.<br>The expanded human kallikrein (KLK) gene family: genomic organisation, tissue-specific expression and potential functions<br>Biol Chem (2001) 382, 5-14. PubMed  Europe PubMed DOI  V
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