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Literature for peptidase S01.243: lumbrokinase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, A Assay, E Expression, V Review, U Therapeutic. To select only the references relevant to a single topic, click the link above. See explanation.)

    2023
  1. Stephani,L., Rahayu,P., Retnoningrum,D., Suhartono,M.T., Rachmawati,H. and Tjandrawinata,R.R.
    Purification and proteomic analysis of potent fibrinolytic enzymes extracted from Lumbricus rubellus
    Proteome Sci21, 8-8. PubMed  Europe PubMed DOI
    2. 2022
  2. Metkar,S.K., Girigoswami,A., Bondage,D.D., Shinde,U.G. and Girigoswami,K.
    The potential of lumbrokinase and serratiopeptidase for the degradation of Abeta 1-42 peptide - an in vitro and in silico approach
    Int J Neurosci1-12. PubMed  Europe PubMed DOI
    3. 2020
  3. Metkar,S.K., Girigoswami,A., Vijayashree,R. and Girigoswami,K.
    Attenuation of subcutaneous insulin induced amyloid mass in vivo using Lumbrokinase and Serratiopeptidase
    Int J Biol Macromol163, 128-134. PubMed  Europe PubMed DOI
    4. 2019
  4. Liao,J., Ren,X., Yang,B., Li,H., Zhang,Y. and Yin,Z.
    Targeted thrombolysis by using c-RGD-modified N,N,N-trimethyl chitosan nanoparticles loaded with lumbrokinase
    Drug Dev Ind Pharm45, 88-95. PubMed  Europe PubMed DOI  U
    5. 2018
  5. Akazawa,S.I., Tokuyama,H., Sato,S., Watanabe,T., Shida,Y. and Ogasawara,W.
    High-pressure tolerance of earthworm fibrinolytic and digestive enzymes
    J Biosci Bioeng125, 155-159. PubMed  Europe PubMed DOI
  6. Hu,B., Yan,Y., Tong,F., Xu,L., Zhu,J., Xu,G. and Shen,R.
    Lumbrokinase/paclitaxel nanoparticle complex: potential therapeutic applications in bladder cancer
    Int J Nanomedicine13, 3625-3640. PubMed  Europe PubMed DOI
  7. Wang,Y.H., Li,S.A., Huang,C.H., Su,H.H., Chen,Y.H., Chang,J.T. and Huang,S.S.
    Sirt1 activation by post-ischemic treatment with lumbrokinase protects against myocardial ischemia-reperfusion injury
    Front Pharmacol9, 636-636. PubMed  Europe PubMed DOI
    8. 2017
  8. Dickey,A., Wang,N., Cooper,E., Tull,L., Breedlove,D., Mason,H., Liu,D. and Wang,K.Y.
    Transient expression of lumbrokinase (PI239) in tobacco (Nicotiana tabacum) using a geminivirus-based single replicon system dissolves fibrin and blood clots
    Evid Based Complement Alternat Med2017, 6093017-6093017. PubMed  Europe PubMed DOI  E
  9. Jin,M., Jin,G., Huang,W. and Gao,Z.
    PEGylation of lumbrokinase improves pharmacokinetic profile and enhances antithrombotic effect in a rat carotid artery thrombosis model
    Mol Med Rep16, 4909-4914. PubMed  Europe PubMed DOI  U
  10. Verma,M.K. and Pulicherla,K.K.
    Broad substrate affinity and catalytic diversity of fibrinolytic enzyme from Pheretima posthumous. Purification and molecular characterization study
    Int J Biol Macromol95, 1011-1021. PubMed  Europe PubMed DOI
    11. 2015
  11. Fu,Y.T., Sheu,S.Y., Chen,Y.S., Chen,K.Y. and Yao,C.H.
    Porous gelatin/tricalcium phosphate/genipin composites containing lumbrokinase for bone repair
    Bone78, 15-22. PubMed  Europe PubMed DOI  U
  12. Lee,H.C., Hsu,Y.M., Tsai,C.C., Ke,C.J., Yao,C.H. and Chen,Y.S.
    Improved peripheral nerve regeneration in streptozotocin-induced diabetic rats by oral lumbrokinase
    Am J Chin Med43, 215-230. PubMed  Europe PubMed DOI
    13. 2014
  13. Guan,C., Ji,J., Jin,C., Wang,G., Li,X. and Guan,W.
    Expression of cholera toxin B subunit-lumbrokinase in edible sunflower seeds-the use of transmucosal carrier to enhance its fusion protein's effect on protection of rats and mice against thrombosis
    Biotechnol Prog30, 1029-1039. PubMed  Europe PubMed DOI
    14. 2013
  14. Cao,Y.J., Zhang,X., Wang,W.H., Zhai,W.Q., Qian,J.F., Wang,J.S., Chen,J., You,N.X., Zhao,Z., Wu,Q.Y., Xu,Y., Yuan,L., Li,R.X. and Liu,C.F.
    Oral fibrinogen-depleting agent lumbrokinase for secondary ischemic stroke prevention: results from a multicenter, randomized, parallel-group and controlled clinical trial
    Chin Med J (Engl)126, 4060-4065. PubMed  Europe PubMed DOI  U
  15. Joo,H.S., Ra,K.S., Park,H.S. and Choi,J.W.
    Molecular cloning and functional expression of a fibrinolytic protease gene from the polychaeta, Periserrula leucophryna
    Biotechnol Bioprocess Eng18, 209-217. DOI
  16. Wang,K.Y., Tull,L., Cooper,E., Wang,N. and Liu,D.
    Recombinant protein production of earthworm lumbrokinase for potential antithrombotic application
    Evid Based Complement Alternat Med2013, 783971-783971. PubMed  Europe PubMed DOI  E
    17. 2012
  17. Wang,Y.Y., Fu,W.L., Wang,M., Zou,M.J., Xu,T., Wang,J.X., Zhang,H. and Xu,D.G.
    [Quantitative method for detection of plasma lumbrokinase content and its assessment]
    Zhongguo Shi Yan Xue Ye Xue Za Zhi20, 1492-1495. PubMed  Europe PubMed  A
  18. Zhou,Y. and He,R.Q.
    Earthworm fibrinolytic enzymes
    [ISSN:978-0-12-407742-3]3, 2953-2958. DOI
    19. 2011
  19. Pan,R., Zhou,Y., He,H.J. and He,R.Q.
    An enzyme from the earthworm Eisenia fetida is not only a protease but also a deoxyribonuclease
    Biochem Biophys Res Commun407, 113-117. PubMed  Europe PubMed DOI
  20. Sharma,A., Sonah,H., Deshmukh,R.K., Gupta,N.K., Singh,N.K. and Sharma,T.R.
    Cloning of fibrinolytic protease-0 (Efp-0) gene from diverse earthworm individuals
    Indian J Biotechnol10, 270-273.
  21. Ueda,M., Yamashita,T., Nakazawa,M., Miyatake,K., Ohki,S., Sakaguchi,M. and Inouye,K.
    Purification and characterization of a new serine protease (EF-SP2) with anti-plant viral activity from Eisenia foetida: analysis of anti-plant viral activity of EF-SP2
    Process Biochem46, 1711-1716. DOI
    22. 2010
  22. Xu,Z.R., Yang,Y.M., Gui,Q.F., Zhang,L.N. and Hu,L.
    Expression, purification, and characterization of recombinant lumbrokinase PI239 in Escherichia coli
    Protein Expr Purif69, 198-203. PubMed  Europe PubMed DOI  E
  23. Yan,X.M., Kim,C.H., Lee,C.K., Shin,J.S., Cho,I.H. and Sohn,U.D.
    Intestinal absorption of fibrinolytic and proteolytic lumbrokinase extracted from earthworm, Eisenia andrei
    Korean J Physiol Pharmacol14, 71-75. PubMed  Europe PubMed DOI
    24. 2007
  24. Zhao,J., Pan,R., He,J., Liu,Y., Li,D.F. and He,R.Q.
    Eisenia fetida protease-III-1 functions in both fibrinolysis and fibrogenesis
    J Biomed Biotechnol2007, 97654-97654. PubMed  Europe PubMed DOI
  25. Zhao,J., Xiao,R., He,J., Pan,R., Fan,R., Wu,C., Liu,X., Liu,Y. and He,R.Q.
    In situ localization and substrate specificity of earthworm protease-II and protease-III-1 from Eisenia fetida
    Int J Biol Macromol40, 67-75. PubMed  Europe PubMed DOI
    26. 2006
  26. Zhao,X.Y., Gao,S., Cui,D.L. and Geng,F.T.
    [In silico cloning of EfP-0, a novel earthworm fibrinolytic enzyme gene and verification of its coding region by RT-PCR]
    Sheng Wu Gong Cheng Xue Bao22, 897-901. PubMed  Europe PubMed DOI
    27. 2005
  27. [YEAR:6-5-2005]Wang,F., Wang,C., Li,M., Zhang,J.P., Gui,L.L., An,X.M. and Chang,W.R.
    Crystal structure of earthworm fibrinolytic enzyme component B: a novel, glycosylated two-chained trypsin
    J Mol Biol348, 671-685. PubMed  Europe PubMed DOI  S
    28. 2004
  28. Cho,I.H., Choi,E.S., Lim,H.G. and Lee,H.H.
    Purification and characterization of six fibrinolytic serine-proteases from earthworm Lumbricus rubellus
    J Biochem Mol Biol37, 199-205. PubMed  Europe PubMed
  29. [YEAR:30-9-2004]Cho,I.H., Choi,E.S. and Lee,H.H.
    Molecular cloning, sequencing, and expression of a fibrinolytic serine-protease gene from the earthworm Lumbricus rubellus
    J Biochem Mol Biol37, 574-581. PubMed  Europe PubMed
  30. Dong,G.Q., Yuan,X.L., Shan,Y.J., Zhao,Z.H., Chen,J.P. and Cong,Y.W.
    Molecular cloning and characterization of cDNA encoding fibrinolytic enzyme-3 from earthworm Eisenia foetida
    Acta Biochim Biophys Sin (Shanghai)36, 303-308. PubMed  Europe PubMed
  31. Nakajima,N., Ishihara,K. and Sugimoto,M.
    Earthworm fibrinolytic enzymes
    [ISSN:0-12-079610-4]2, 1689-1691.  V
    32. 2002
  32. Nakajima,N., Ishihara,K., Sugimoto,M., Nakahara,T. and Tsuji,H.
    Further stabilization of earthworm serine protease by chemical modification and immobilization
    Biosci Biotechnol Biochem66, 2739-2742. PubMed  Europe PubMed DOI
    33. 2001
  33. [YEAR:15-6-2001]Fan,Q., Wu,C., Li,L., Fan,R., Wu,C., Hou,Q.M. and He,R.Q.
    Some features of intestinal absorption of intact fibrinolytic enzyme III-1 from Lumbricus rubellus
    Biochim Biophys Acta1526, 286-292. PubMed  Europe PubMed DOI
  34. Sugimoto,M. and Nakajima,N.
    Molecular cloning, sequencing, and expression of cDNA encoding serine protease with fibrinolytic activity from earthworm
    Biosci Biotechnol Biochem65, 1575-1580. PubMed  Europe PubMed DOI
    35. 2000
  35. Jin,L., Jin,H., Zhang,G. and Xu,G.
    Changes in coagulation and tissue plasminogen activator after the treatment of cerebral infarction with lumbrokinase
    Clin Hemorheol Microcirc23, 213-218. PubMed  Europe PubMed
    36. 1999
  36. Nakajima,N., Sugimoto,M., Ishihara,K., Nakamura,K. and Hamada,H.
    Further characterization of earthworm serine proteases: cleavage specificity against peptide substrates and on autolysis
    Biosci Biotechnol Biochem63, 2031-2033. PubMed  Europe PubMed DOI
  37. Park,Y., Ryu,E., Kim,H., Jeong,J., Kim,J., Shim,J., Jeon,S., Jo,Y., Kim,W. and Min,B.
    Characterization of antithrombotic activity of lumbrokinase-immobilized polyurethane valves in the total artificial heart
    Artif Organs23, 210-214. PubMed  Europe PubMed DOI
    38. 1996
  38. Nakajima,N., Ishihara,K., Sugimoto,M., Sumi,H., Mikuni,K. and Hamada,H.
    Chemical modification of earthworm fibrinolytic enzyme with human serum albumin fragment and characterization of the protease as a therapeutic enzyme
    Biosci Biotechnol Biochem60, 293-300. PubMed  Europe PubMed DOI
    39. 1995
  39. Ryu,G.H., Han,D.K., Park,S., Kim,M., Kim,Y.H. and Min,B.
    Surface characteristics and properties of lumbrokinase-immobilized polyurethane
    J Biomed Mater Res29, 403-409. PubMed  Europe PubMed DOI
    40. 1994
  40. Ryu,G.H., Park,S., Kim,M., Han,D.K., Kim,Y.H. and Min,B.
    Antithrombogenicity of lumbrokinase-immobilized polyurethane
    J Biomed Mater Res28, 1069-1077. PubMed  Europe PubMed DOI
    41. 1993
  41. Kim,J.S., Kang,J.K., Chang,H.C., Lee,M., Kim,G.S., Lee,D.K., Kim,S.T., Kim,M. and Park,S.
    The thrombolytic effect of lumbrokinase is not as potent as urokinase in a rabbit cerebral embolism model
    J Korean Med Sci8, 117-120. PubMed  Europe PubMed
  42. Nakajima,N., Mihara,H. and Sumi,H.
    Characterization of potent fibrinolytic enzymes in earthworm, Lumbricus rubellus
    Biosci Biotechnol Biochem57, 1726-1730. PubMed  Europe PubMed DOI
  43. Ryu,G.H., Park,S., Han,D.K., Kim,Y.H. and Min,B.
    Antithrombotic activity of a lumbrokinase immobilized polyurethane surface
    ASAIO J39, M314-M318. PubMed  Europe PubMed DOI
    44. 1991
  44. Mihara,H., Sumi,H., Yoneta,T., Mizumoto,H., Ikeda,R., Seiki,M. and Maruyama,M.
    A novel fibrinolytic enzyme extracted from the earthworm, Lumbricus rubellus
    Jpn J Physiol41, 461-472. PubMed  Europe PubMed

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