$VAR1 = undef;

Summary for peptidase S01.243: lumbrokinase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

 

Names
MEROPS Namelumbrokinase
Other namesearthworm fibrinolytic enzyme-b, EFE-b, F-III protease (Lumbricus rubellus), fibrinolytic endopeptidase (Lumbricus rubellus), fibrinolytic enzyme-3 (Eisenia fetida), EfP-0-1, EfP-0-2, EfP-III-1, EfP-III-2
Domain architecture
MEROPS Classification
Classification Clan PA >> Subclan PA(S) >> Family S1 >> Subfamily A >> S01.243
Holotypelumbrokinase (Lumbricus rubellus) (peptidase unit: 45-283), MERNUM MER0003617
History Identifier created: MEROPS 3.02 (25 June 1998)
Activity
Catalytic typeSerine
NC-IUBMBNot yet included in IUBMB recommendations.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/RkflScissile bond-/v/-/g (based on 25 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 2 4 5 0 3 1 4 5
Pro 0 1 5 0 0 0 1 0
Ala 1 3 1 0 2 3 0 0
Val 1 3 1 0 3 6 1 0
Leu 0 1 2 2 2 1 0 1
Ile 2 2 0 0 0 1 1 1
Met 1 0 0 0 1 0 0 0
Phe 1 0 2 3 1 2 2 2
Tyr 1 1 0 1 3 0 0 1
Trp 0 0 0 0 0 0 0 0
Ser 0 1 0 0 1 0 3 4
Thr 0 2 1 0 2 2 3 1
Cys 1 0 0 0 0 0 0 0
Asn 1 1 1 0 1 1 0 0
Gln 0 0 1 0 0 0 0 0
Asp 1 0 0 0 0 1 1 1
Glu 2 3 4 0 0 1 3 0
Lys 1 1 0 4 0 0 0 2
Arg 4 0 1 15 1 0 0 1
His 1 1 0 0 1 1 0 0