Literature for peptidase S01.233: plasmin

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors Pharma

(Topics flags: S Structure, A Assay, T Target, K Knockout, P Specificity, E Expression, V Review, M Mutation, I Inhibitor, U Therapeutic. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Pirillo,E., Freenor,V., Wamba,B.E.N., Bhatnagar,S., Mondal,T. and Tushir-Singh,J.
    An evolutionary T119R substitution in the macaque T-cell immunoreceptor TIGIT enables proteolytic shedding and reveals clinical antibody vulnerabilities
    J Biol Chem (2025) , 110962-110962. PubMed  Europe PubMed DOI
  2. 2024
  3. Al-Horani,R.A. and Aliter,K.F.
    Triple Action of Lignosulfonic Acid Sodium: Anti-protease, Antioxidant, and Anti-inflammatory Effects of a Polymeric Heparin Mimetic
    Med Chem (2024) 20, 414-421. PubMed  Europe PubMed DOI  I
  4. Al-Horani,R.A.
    Revisiting the effect of cholesteryl sulfate on clotting and fibrinolysis: Inhibition of human thrombin and other human blood proteases
    Heliyon (2024) 10, e28017-e28017. PubMed  Europe PubMed DOI  PMC  EPMC  I
  5. Barrett,C.D., Moore,P.K., Moore,E.E., Moore,H.B., Chandler,J.G., Siddiqui,H., Maginot,E.R., Sauaia,A., Perez-Calatayud,A.A., Buesing,K., Wang,J., Davila-Chapa,C., Hershberger,D., Douglas,I., Pieracci,F.M. and Yaffe,M.B.
    Plasminogen Degradation by Neutrophil Elastase in Pleural Infection, Not High Plasminogen Activator Inhibitor-1 (PAI-1), is the Cause of Intrapleural Lytic Failure
    Chest (2024) PubMed  Europe PubMed DOI
  6. Bharadwaj,A.G., Okura,G.C., Woods,J.W., Allen,E.A., Miller,V.A., Kempster,E., Hancock,M.A., Gujar,S., Slibinskas,R. and Waisman,D.M.
    Identification and characterization of calreticulin as a novel plasminogen receptor
    J Biol Chem (2024) 300, 105465-105465. PubMed  Europe PubMed DOI  PMC  EPMC
  7. Brito-Robinson,T., Ayinuola,Y.A., Ploplis,V.A. and Castellino,F.J.
    Plasminogen missense variants and their involvement in cardiovascular and inflammatory disease
    Front Cardiovasc Med (2024) 11, 1406953-1406953. PubMed  Europe PubMed DOI  PMC  EPMC
  8. Dai,X., Yang,J., Lv,L., Wang,C. and Bian,L.
    Molecular recognition and binding between human plasminogen Kringle 5 and alpha-chain of human complement component C3b by frontal chromatography and dynamics simulation
    J Chromatogr A (2024) 1718, 464673-464673. PubMed  Europe PubMed DOI
  9. Dickeson,S.K., Kumar,S., Sun,M.F., Litvak,M., He,T.Z., Phillips,D.R., Roberts,E.T., Feener,E.P., Law,R.H.P. and Gailani,D.
    A mechanism for hereditary angioedema caused by a methionine-379-to-lysine substitution in kininogens
    Blood (2024) 143, 641-650. PubMed  Europe PubMed DOI  PMC  EPMC
  10. Otmani,H.E., Vanhoorelbeke,K. and Tersteeg,C.
    Improving our understanding on the clinical role of plasmin-mediated von Willebrand factor degradation
    Curr Opin Hematol (2024) 31, 245-250. PubMed  Europe PubMed DOI  V
  11. Tang,D., Khakzad,H., Hjortswang,E., Malmstrom,L., Ekstrom,S., Happonen,L. and Malmstrom,J.
    Streptolysin O accelerates the conversion of plasminogen to plasmin
    Nat Commun (2024) 15, 10212-10212. PubMed  Europe PubMed DOI  PMC  EPMC
  12. Uguen,K., Frey,T., Muthaffar,O., Decarie,J.C., Ameziane,N., Boissel,S., Baradaran-Heravi,Y., Rauch,A., Oprea,G., Rad,A., Steindl,K. and Michaud,J.L.
    Loss of tissue-type plasminogen activator causes multiple developmental anomalies
    Brain Commun (2024) 6, fcae408-fcae408. PubMed  Europe PubMed DOI  PMC  EPMC
  13. Vrzalova,A. and Vrzal,R.
    Orchestra of ligand-activated transcription factors in the molecular symphony of SERPINE 1 / PAI-1 gene regulation
    Biochimie (2024) PubMed  Europe PubMed DOI  V
  14. 2023
  15. Afosah,D.K., Fayyad,R.M., Puliafico,V.R., Merrell,S., Langmia,E.K., Diagne,S.R., Al-Horani,R.A. and Desai,U.R.
    Homogeneous, Synthetic, Non-Saccharide Glycosaminoglycan Mimetics as Potent Inhibitors of Human Cathepsin G
    Biomolecules (2023) 13 PubMed  Europe PubMed DOI  PMC  EPMC  I
  16. Ferreira,G.C., Bomediano Camillo,L.M. and Sasaki,S.D.
    Structural and functional properties of rBmTI-A: A Kunitz-BPTI serine protease inhibitor with therapeutical potential
    Biochimie (2023) 204, 7- PubMed  Europe PubMed DOI
  17. Kaur,P., Sethi,D., Hade,M.D., Kaur,J. and Dikshit,K.L.
    C-terminal lysine residues enhance plasminogen activation by inducing conformational flexibility and stabilization of activator complex of staphylokinase with plasmin
    Arch Biochem Biophys (2023) 743, 109671-109671. PubMed  Europe PubMed DOI
  18. Moore-Lotridge,S.N., Hajdu,K.S., Hou,B.Q., Gibson,B.H.Y. and Schoenecker,J.G.
    Maintaining the balance: the critical role of plasmin activity in orthopedic surgery injury response
    J Thromb Haemost (2023) 21, 2653-2665. PubMed  Europe PubMed DOI  V
  19. Yang,J., Cha,L., Wang,Y., Zhang,Q., Tang,X., Shao,J. and Duan,Z.
    L-Palmitoylcarnitine potentiates plasmin and tPA to inhibit thrombosis
    Nat Prod Bioprospect (2023) 13, 48-48. PubMed  Europe PubMed DOI  PMC  EPMC
  20. 2022
  21. Bryk-Wiazania,A.H., Cysewski,D., Oclon,E. and Undas,A.
    Mass-spectrometric identification of oxidative modifications in plasma-purified plasminogen: Association with hypofibrinolysis in patients with acute pulmonary embolism
    Biochem Biophys Res Commun (2022) 621, 53-58. PubMed  Europe PubMed DOI
  22. Loef,E.J., Sheppard,H.M., Birch,N.P. and Dunbar,P.R.
    Plasminogen and plasmin can bind to human T cells and generate truncated CCL21 that increases dendritic cell chemotactic responses
    J Biol Chem (2022) 298, 102112-102112. PubMed  Europe PubMed DOI  PMC  EPMC
  23. Mehner,C., Hockla,A., Coban,M., Madden,B., Estrada,R., Radisky,D.C. and Radisky,E.S.
    Activity-based protein profiling reveals active serine proteases that drive malignancy of human ovarian clear cell carcinoma
    J Biol Chem (2022) 298, 102146-102146. PubMed  Europe PubMed DOI  PMC  EPMC
  24. Pascini,T.V., Jeong,Y.J., Huang,W., Pala,Z.R., Sa,J.M., Wells,M.B., Kizito,C., Sweeney,B., Alves E Silva, Andrew,D.J., Jacobs-Lorena,M. and Vega-Rodriguez,J.
    Transgenic Anopheles mosquitoes expressing human PAI-1 impair malaria transmission
    Nat Commun (2022) 13, 2949-2949. PubMed  Europe PubMed DOI  PMC  EPMC
  25. Vasilyeva,A., Yurina,L., Ivanov,V., Azarova,D., Gavrilina,E., Indeykina,M., Bugrova,A., Kononikhin,A., Nikolaev,E. and Rosenfeld,M.
    The effect of hypochlorite- and peroxide-induced oxidation of plasminogen on damage to the structure and biological activity
    Int J Biol Macromol (2022) 206, 64-73. PubMed  Europe PubMed DOI
  26. 2021
  27. Choudhary,K., Patel,P.K., Are,V.N., Makde,R.D. and Hajela,K.
    Mannose-binding lectin-associated serine protease-1 cleaves plasminogen and plasma fibronectin: prefers plasminogen over known fibrinogen substrate
    Blood Coagul Fibrinolysis (2021) 32, 504-512. PubMed  Europe PubMed DOI
  28. Friedrich,C., Neugebauer,L., Zamora,M., Robles,J.P., Martinez de la Escalera,G., Clapp,C., Bertsch,T. and Triebel,J.
    Plasmin generates vasoinhibin-like peptides by cleaving prolactin and placental lactogen
    Mol Cell Endocrinol (2021) 538, 111471-111471. PubMed  Europe PubMed DOI
  29. Heestermans,M., Naudin,C., Mailer,R.K., Konrath,S., Klaetschke,K., Jamsa,A., Frye,M., Deppermann,C., Pula,G., Kuta,P., Friese,M.A., Gelderblom,M., Sickmann,A., Preston,R.J.S., Nofer,J.R., Rose-John,S., Butler,L.M., Salomon,O., Stavrou,E.X. and Renne,T.
    Identification of the factor XII contact activation site enables sensitive coagulation diagnostics
    Nat Commun (2021) 12, 5596-5596. PubMed  Europe PubMed DOI  PMC  EPMC
  30. Ismail,A.A., Shaker,B.T. and Bajou,K.
    The Plasminogen-Activator Plasmin System in Physiological and Pathophysiological Angiogenesis
    Int J Mol Sci (2021) 23 PubMed  Europe PubMed DOI  PMC  EPMC
  31. Kryza,T., Khan,T., Lovell,S., Harrington,B.S., Yin,J., Porazinski,S., Pajic,M., Koistinen,H., Rantala,J.K., Dreyer,T., Magdolen,V., Reuning,U., He,Y., Tate,E.W. and Hooper,J.D.
    Substrate-biased activity-based probes identify proteases that cleave receptor CDCP1
    Nat Chem Biol (2021) PubMed  Europe PubMed DOI
  32. Kunnapuu,J., Bokharaie,H. and Jeltsch,M.
    Proteolytic Cleavages in the VEGF Family: Generating Diversity among Angiogenic VEGFs, Essential for the Activation of Lymphangiogenic VEGFs
    Biology (Basel) (2021) 10 PubMed  Europe PubMed DOI  PMC  EPMC
  33. Miszta,A., Huskens,D., Donkervoort,D., Roberts,M.J.M., Wolberg,A.S. and de Laat,B.
    Assessing Plasmin Generation in Health and Disease
    Int J Mol Sci (2021) 22 PubMed  Europe PubMed DOI  PMC  EPMC  V
  34. Pala,Z.R., Ernest,M., Sweeney,B., Jeong,Y.J., Pascini,T.V., Alves E Silva and Vega-Rodriguez,J.
    Beyond cuts and scrapes: plasmin in malaria and other vector-borne diseases
    Trends Parasitol (2021) PubMed  Europe PubMed DOI  V
  35. Walvekar,V.A., Ramesh,K., Jobichen,C., Kannan,M., Sivaraman,J., Kini,R.M. and Mok,Y.K.
    Crystal structure of Aedes aegypti trypsin inhibitor in complex with mu-plasmin reveals role for scaffold stability in Kazal-type serine protease inhibitor
    Protein Sci (2021) PubMed  Europe PubMed DOI
  36. Wang,M., Xie,Y. and Qin,D.
    Proteolytic cleavage of proBDNF to mBDNF in neuropsychiatric and neurodegenerative diseases
    Brain Res Bull (2021) 166, 172-184. PubMed  Europe PubMed DOI
  37. Yazgan,N.N., Bulat,T., Topcu,A., Dudak,F.C., Boyaci,I.H. and Tamer,U.
    Surface-enhanced Raman scattering-based detection of plasmin activity by specific peptide substrate
    Food Chem (2021) 372, 131235-131235. PubMed  Europe PubMed DOI
  38. 2020
  39. Ayinuola,Y.A., Brito-Robinson,T., Ayinuola,O., Beck,J.E., Cruz-Topete,D., Lee,S.W., Ploplis,V.A. and Castellino,F.J.
    Streptococcus co-opts a conformational lock in human plasminogen to facilitate streptokinase cleavage and bacterial virulence
    J Biol Chem (2020) PubMed  Europe PubMed DOI
  40. Baghban,R., Farajnia,S., Ghasemi,Y., Hoseinpoor,R., Safary,A., Mortazavi,M. and Zarghami,N.
    Mutational Analysis of Ocriplasmin to Reduce Proteolytic and Autolytic Activity in Pichia pastoris
    Biol Proced Online (2020) 22, 25-25. PubMed  Europe PubMed DOI  PMC  EPMC
  41. Brunet,J.G., Sharma,T., Tasneem,S., Liang,M., Wilson,M.D., Rivard,G.E. and Hayward,C.P.M.
    Thrombin generation abnormalities in Quebec platelet disorder
    Int J Lab Hematol (2020) , e13302-e13302. PubMed  Europe PubMed DOI  I
  42. Heissig,B., Salama,Y., Takahashi,S., Osada,T. and Hattori,K.
    The multifaceted role of plasminogen in inflammation
    Cell Signal (2020) 75, 109761-109761. PubMed  Europe PubMed DOI  PMC  EPMC  V
  43. Klaassen,K., Stankovic,B., Zukic,B., Kotur,N., Gasic,V., Pavlovic,S. and Stojiljkovic,M.
    Functional prediction and comparative population analysis of variants in genes for proteases and innate immunity related to SARS-CoV-2 infection
    Infect Genet Evol (2020) 84, 104498-104498. PubMed  Europe PubMed DOI  PMC  EPMC
  44. Marceau,F., Rivard,G.E., Gauthier,J.M., Binkley,K.E., Bonnefoy,A., Boccon-Gibod,I., Bouillet,L., Picard,M., Levesque,G., Elfassy,H.L., Bachelard,H., Hebert,J. and Bork,K.
    Measurement of Bradykinin Formation and Degradation in Blood Plasma: Relevance for Acquired Angioedema Associated With Angiotensin Converting Enzyme Inhibition and for Hereditary Angioedema Due to Factor XII or Plasminogen Gene Variants
    Front Med (Lausanne) (2020) 7, 358-358. PubMed  Europe PubMed DOI  PMC  EPMC  I
  45. Medcalf,R.L., Keragala,C.B. and Myles,P.S.
    Fibrinolysis and COVID-19: A plasmin paradox
    J Thromb Haemost (2020) PubMed  Europe PubMed DOI  PMC  EPMC
  46. Miles,L.A., Vago,J.P., Sousa,L.P. and Parmer,R.J.
    Functions of the Plasminogen Receptor, Plg-RKT
    J Thromb Haemost (2020) PubMed  Europe PubMed DOI  V
  47. Moraes,C.T.P., Longo,J., Silva,L.B., Pimenta,D.C., Carvalho,E., Morone,M.S.L.C., da Ros,N., Serrano,S.M.T., Santos,A.C.M., Piazza,R.M.F., Barbosa,A.S. and Elias,W.P.
    Surface Protein Dispersin of Enteroaggregative Escherichia coli Binds Plasminogen That Is Converted Into Active Plasmin
    Front Microbiol (2020) 11, 1222-1222. PubMed  Europe PubMed DOI  PMC  EPMC
  48. Pedersen,N.B., Stolberg,C.R., Mundbjerg,L.H., Juhl,C.B., Gram,B., Funch-Jensen,P., de Maat,M.P.M., Munster,A.B. and Bladbjerg,E.M.
    Reductions in plasmin inhibitor and fibrinogen predict the improved fibrin clot lysis 6 months after obesity surgery
    Clin Obes (2020) , e12397-e12397. PubMed  Europe PubMed DOI
  49. Sanda,T., Yoshimura,M., Hyodo,K., Ishii,H. and Yamashita,T.
    Effects of Long-term Thrombin Inhibition (Dabigatran Etexilate) on Spontaneous Thrombolytic Activity during the Progression of Atherosclerosis in ApoE(-/-)-LDLR(-/-) Double-Knockout Mice
    Korean Circ J (2020) 50, 804-816. PubMed  Europe PubMed DOI  I
  50. Seth,S., Batra,J. and Srinivasan,S.
    COVID-19: Targeting Proteases in Viral Invasion and Host Immune Response
    Front Mol Biosci (2020) 7, 215-215. PubMed  Europe PubMed DOI  PMC  EPMC  V
  51. Steinmetzer,T., Pilgram,O., Wenzel,B.M. and Wiedemeyer,S.J.A.
    Fibrinolysis inhibitors: potential drugs for the treatment and prevention of bleeding
    J Med Chem (2020) 63, 1445-1472. PubMed  Europe PubMed DOI  I
  52. Suzuki,Y., Sano,H., Mochizuki,L., Honkura,N. and Urano,T.
    Activated platelet-based inhibition of fibrinolysis via thrombin-activatable fibrinolysis inhibitor activation system
    Blood Adv (2020) 4, 5501-5511. PubMed  Europe PubMed DOI  PMC  EPMC
  53. Thierry,A.R.
    Anti-protease Treatments Targeting Plasmin(ogen) and Neutrophil Elastase May Be Beneficial in Fighting COVID-19
    Physiol Rev (2020) 100, 1597-1598. PubMed  Europe PubMed DOI  PMC  EPMC
  54. Vadivel,K., Zaiss,A.K., Kumar,Y., Fabian,F.M., Ismail,A.E.A., Arbing,M.A., Buchholz,W.G., Velander,W.H. and Bajaj,S.P.
    Enhanced Antifibrinolytic Efficacy of a Plasmin-Specific Kunitz-Inhibitor (60-Residue Y11T/L17R with C-Terminal IEK) of Human Tissue Factor Pathway Inhibitor Type-2 Domain1
    J Clin Med (2020) 9 PubMed  Europe PubMed DOI  PMC  EPMC
  55. Weihs,F., Peh,A. and Dacres,H.
    A red-shifted bioluminescence resonance energy transfer (BRET) biosensing system for rapid measurement of plasmin activity in human plasma
    Anal Chim Acta (2020) 1102, 99-108. PubMed  Europe PubMed DOI  A
  56. 2019
  57. Barbosa da Cruz,D., Helms,J., Aquino,L.R., Stiel,L., Cougourdan,L., Broussard,C., Chafey,P., Ries-Kautt,M., Meziani,F., Toti,F., Gaussem,P. and Angles-Cano,E.
    DNA-bound elastase of neutrophil extracellular traps degrades plasminogen, reduces plasmin formation, and decreases fibrinolysis: proof of concept in septic shock plasma
    FASEB J (2019) 33, 14270-14280. PubMed  Europe PubMed DOI
  58. Swedberg,J.E., Wu,G., Mahatmanto,T., Durek,T., Caradoc-Davies,T.T., Whisstock,J.C., Law,R.H.P. and Craik,D.J.
    Highly potent and selective plasmin inhibitors based on the sunflower trypsin inhibitor-1 scaffold attenuate fibrinolysis in plasma
    J Med Chem (2019) 62, 552-560. PubMed  Europe PubMed DOI
  59. Trinh,T.H.T., Kim,J., Lee,C.H. and Ryou,C.
    Non-ionic detergents Nonidet P-40 and Triton X-100 increase enzymatic activity of plasmin
    Biochem Biophys Res Commun (2019) 512, 314-318. PubMed  Europe PubMed DOI
  60. Wu,G., Quek,A.J., Caradoc-Davies,T.T., Ekkel,S.M., Mazzitelli,B., Whisstock,J.C. and Law,R.H.P.
    Structural studies of plasmin inhibition
    Biochem Soc Trans (2019) 47, 541-557. PubMed  Europe PubMed DOI  I
  61. Zhao,T., Houng,A. and Reed,G.L.
    Termination of bleeding by a specific anticatalytic antibody against plasmin
    J Thromb Haemost (2019) 17, 1461-1469. PubMed  Europe PubMed DOI
  62. 2018
  63. Clark,C.C., Mebius,M.M., de Maat,S., Tielens,A.G.M., DE Groot,P.G., Urbanus,R.T., Fijnheer,R., Hazenberg,B.P.C., van Hellemond,J.J. and Maas,C.
    Truncation of ADAMTS13 by plasmin enhances its activity in plasma
    Thromb Haemost (2018) 118, 471-479. PubMed  Europe PubMed DOI
  64. Nguyen,N.T.T., Rottgerding,F., Devraj,G., Lin,Y.P., Koenigs,A. and Kraiczy,P.
    The complement binding and inhibitory protein CbiA of Borrelia miyamotoi degrades extracellular matrix components by interacting with plasmin(ogen)
    Front Cell Infect Microbiol (2018) 8, 23-23. PubMed  Europe PubMed DOI  PMC  EPMC
  65. 2017
  66. Draxler,D.F., Sashindranath,M. and Medcalf,R.L.
    Plasmin: a modulator of immune function
    Semin Thromb Hemost (2017) 43, 143-153. PubMed  Europe PubMed DOI
  67. Law,R.H.P., Wu,G., Leung,E.W.W., Hidaka,K., Quek,A.J., Caradoc-Davies,T.T., Jeevarajah,D., Conroy,P.J., Kirby,N.M., Norton,R.S., Tsuda,Y. and Whisstock,J.C.
    X-ray crystal structure of plasmin with tranexamic acid-derived active site inhibitors
    Blood Adv (2017) 1, 766-771. PubMed  Europe PubMed DOI  PMC  EPMC  S  I
  68. Schmidt,T.C., Eriksson,P.O., Gustafsson,D., Cosgrove,D., Frolund,B. and Bostrom,J.
    Discovery and evaluation of anti-fibrinolytic plasmin inhibitors derived from 5-(4-piperidyl)isoxazol-3-ol (4-PIOL)
    J Chem Inf Model (2017) 57, 1703-1714. PubMed  Europe PubMed DOI  I
  69. Shimazu,H., Munakata,S., Tashiro,Y., Salama,Y., Dhahri,D., Eiamboonsert,S., Ota,Y., Onoda,H., Tsuda,Y., Okada,Y., Nakauchi,H., Heissig,B. and Hattori,K.
    Pharmacological targeting of plasmin prevents lethality in a murine model of macrophage activation syndrome
    Blood (2017) 130, 59-72. PubMed  Europe PubMed DOI  T
  70. Yang,C., Wang,L., Zhang,H., Yi,Q., Wang,L., Wang,H. and Song,L.
    The first CUB-domain containing serine protease from Chlamys farreri which might be involved in larval development and immune response
    Dev Comp Immunol (2017) 76, 163-168. PubMed  Europe PubMed DOI
  71. Yuan,Y., Zajicek,J., Qiu,C., Chandrahas,V., Lee,S.W., Ploplis,V.A. and Castellino,F.J.
    Conformationally organized lysine isosteres in Streptococcus pyogenes M protein mediate direct high-affinity binding to human plasminogen
    J Biol Chem (2017) 292, 15016-15027. PubMed  Europe PubMed DOI
  72. Yue,S.-L., Zhou,Z.-J., Peng,Y., Lin,L.-Z., Li,T.-J., Xing,Y.-T., Wang,F.-F., Li,C.-S. and Hu,Y.
    Development and verification of dynamic chromogenic method for determination of human plasmin activity
    Chin J Biol (2017) 30, 74-78.  A
  73. 2016
  74. Chen,Y.W., Yin,S., Lai,Y.J., Johnson,M.D. and Lin,C.Y.
    Plasminogen-dependent matriptase activation accelerates plasmin generation by differentiating primary human keratinocytes
    J Invest Dermatol (2016) 136, 1210-1218. PubMed  Europe PubMed DOI
  75. Gonzalez-Miguel,J., Siles-Lucas,M., Kartashev,V., Morchon,R. and Simon,F.
    Plasmin in parasitic chronic infections: friend or foe?
    Trends Parasitol (2016) 32, 325-335. PubMed  Europe PubMed DOI
  76. Hidaka,K., Gohda,K., Teno,N., Wanaka,K. and Tsuda,Y.
    Active site-directed plasmin inhibitors: extension on the P2 residue
    Bioorg Med Chem (2016) 24, 545-553. PubMed  Europe PubMed DOI  I
  77. Hinkes,S., Wuttke,A., Saupe,S.M., Ivanova,T., Wagner,S., Knorlein,A., Heine,A., Klebe,G. and Steinmetzer,T.
    Optimization of cyclic plasmin inhibitors: from benzamidines to benzylamines
    J Med Chem (2016) 59, 6370-6386. PubMed  Europe PubMed DOI  I
  78. Kakizoe,Y., Miyasato,Y., Onoue,T., Nakagawa,T., Hayata,M., Uchimura,K., Morinaga,J., Mizumoto,T., Adachi,M., Miyoshi,T., Sakai,Y., Tomita,K., Mukoyama,M. and Kitamura,K.
    A serine protease inhibitor attenuates aldosterone-induced kidney injuries via the suppression of plasmin activity
    J Pharmacol Sci (2016) 132, 145-153. PubMed  Europe PubMed DOI  I
  79. Khan,M.A. and Haller,J.A.
    Ocriplasmin for treatment of vitreomacular traction: an update
    Ophthalmol Ther (2016) 5, 147-159. PubMed  Europe PubMed DOI  U
  80. Lee,Y.S., Wang,N.K., Chen,Y.P., Chen,K.J., Hwang,Y.S., Lai,C.C. and Wu,W.C.
    Plasmin enzyme-assisted vitrectomy in pediatric patients with vitreoretinal diseases
    Ophthalmic Res (2016) 56, 193-201. PubMed  Europe PubMed DOI  U
  81. Leung,L.L. and Morser,J.
    Plasmin as a complement C5 convertase
    EBioMedicine (2016) 5, 20-21. PubMed  Europe PubMed DOI  PMC  EPMC
  82. Maleki,A., Tohidi-Zand,S.R., Amirizadeh,N., Dehghan-Haghighi,J., Zanjani,H., Arish,M., Salari,A.M., Mirhosseini,S.M. and Abrishami,M.
    Intravitreal autologous plasmin prepared by urokinase for vitreolysis: a pilot study
    Eur J Ophthalmol (2016) 26, 67-70. PubMed  Europe PubMed DOI
  83. Morescalchi,F., Gambicorti,E., Duse,S., Costagliola,C. and Semeraro,F.
    From the analysis of pharmacologic vitreolysis to the comprehension of ocriplasmin safety
    Expert Opin Drug Saf (2016) 15, 1267-1278. PubMed  Europe PubMed DOI  U
  84. Poturnayova,A., Karpisova,I., Castillo,G., Mezo,G., Kocsis,L., Csampai,A., Keresztes,Z. and Hianik,T.
    Detection of plasmin based on specific peptide substrate using acoustic transducer
    Sens Actuators, B Chem (2016) 223, 591-598. DOI  A
  85. 2015
  86. Al-Horani,R.A., Karuturi,R., White,D.T. and Desai,U.R.
    Plasmin regulation through allosteric, sulfated, small molecules
    Molecules (2015) 20, 608-624. PubMed  Europe PubMed DOI
  87. Alves,N.J. and Kline,J.A.
    Comparative study on the inhibition of plasmin and delta-plasmin via benzamidine derivatives
    Biochem Biophys Res Commun (2015) 457, 358-362. PubMed  Europe PubMed DOI  I
  88. Castillo,G., Pribransky,K., Mezo,G., Kocsis,L., Csampai,A., Nemeth,K., Keresztes,Z. and Hianik,T.
    Electrochemical and photometric detection of plasmin by specific peptide substrate
    Electroanalysis (2015) 27, 789-798. DOI  A
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    Pharmacologic vitreolysis with Ocriplasmin: rationale for use and therapeutic potential in vitreo-retinal disorders
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    Plasmin releases the anti-tumor peptide from the NC1 domain of collagen XIX
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    Discovery of the fibrinolysis inhibitor AZD6564, acting via interference of a protein-protein interaction
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    Synthetic substrates specific to activated plasmin can monitor the enzymatic functional status in situ in breast cancer cells
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  100. Hultman,K., Cortes-Canteli,M., Bounoutas,A., Richards,A.T., Strickland,S. and Norris,E.H.
    Plasmin deficiency leads to fibrin accumulation and a compromised inflammatory response in the mouse brain
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    Multiple exosites distributed across the three domains of streptokinase co-operate to generate high catalytic rates in the streptokinase-plasmin activator complex
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