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Literature for peptidase S01.233: plasmin

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: S Structure, A Assay, T Target, K Knockout, P Specificity, E Expression, V Review, M Mutation, I Inhibitor, U Therapeutic. To select only the references relevant to a single topic, click the link above. See explanation.)

    2024
  1. Al-Horani,R.A. and Aliter,K.F.
    Triple Action of Lignosulfonic Acid Sodium: Anti-protease, Antioxidant, and Anti-inflammatory Effects of a Polymeric Heparin Mimetic
    Med Chem20, 414-421. PubMed  Europe PubMed DOI  I
  2. Al-Horani,R.A.
    Revisiting the effect of cholesteryl sulfate on clotting and fibrinolysis: Inhibition of human thrombin and other human blood proteases
    Heliyon10, e28017-e28017. PubMed  Europe PubMed DOI  I
  3. Barrett,C.D., Moore,P.K., Moore,E.E., Moore,H.B., Chandler,J.G., Siddiqui,H., Maginot,E.R., Sauaia,A., Perez-Calatayud,A.A., Buesing,K., Wang,J., Davila-Chapa,C., Hershberger,D., Douglas,I., Pieracci,F.M. and Yaffe,M.B.
    Plasminogen Degradation by Neutrophil Elastase in Pleural Infection, Not High Plasminogen Activator Inhibitor-1 (PAI-1), is the Cause of Intrapleural Lytic Failure
    Chest PubMed  Europe PubMed DOI
  4. Bharadwaj,A.G., Okura,G.C., Woods,J.W., Allen,E.A., Miller,V.A., Kempster,E., Hancock,M.A., Gujar,S., Slibinskas,R. and Waisman,D.M.
    Identification and characterization of calreticulin as a novel plasminogen receptor
    J Biol Chem300, 105465-105465. PubMed  Europe PubMed DOI
  5. Brito-Robinson,T., Ayinuola,Y.A., Ploplis,V.A. and Castellino,F.J.
    Plasminogen missense variants and their involvement in cardiovascular and inflammatory disease
    Front Cardiovasc Med11, 1406953-1406953. PubMed  Europe PubMed DOI
  6. Dai,X., Yang,J., Lv,L., Wang,C. and Bian,L.
    Molecular recognition and binding between human plasminogen Kringle 5 and alpha-chain of human complement component C3b by frontal chromatography and dynamics simulation
    J Chromatogr A1718, 464673-464673. PubMed  Europe PubMed DOI
  7. Dickeson,S.K., Kumar,S., Sun,M.F., Litvak,M., He,T.Z., Phillips,D.R., Roberts,E.T., Feener,E.P., Law,R.H.P. and Gailani,D.
    A mechanism for hereditary angioedema caused by a methionine-379-to-lysine substitution in kininogens
    Blood143, 641-650. PubMed  Europe PubMed DOI
  8. Otmani,H.E., Vanhoorelbeke,K. and Tersteeg,C.
    Improving our understanding on the clinical role of plasmin-mediated von Willebrand factor degradation
    Curr Opin Hematol31, 245-250. PubMed  Europe PubMed DOI  V
  9. Tang,D., Khakzad,H., Hjortswang,E., Malmstrom,L., Ekstrom,S., Happonen,L. and Malmstrom,J.
    Streptolysin O accelerates the conversion of plasminogen to plasmin
    Nat Commun15, 10212-10212. PubMed  Europe PubMed DOI
  10. Uguen,K., Frey,T., Muthaffar,O., Decarie,J.C., Ameziane,N., Boissel,S., Baradaran-Heravi,Y., Rauch,A., Oprea,G., Rad,A., Steindl,K. and Michaud,J.L.
    Loss of tissue-type plasminogen activator causes multiple developmental anomalies
    Brain Commun6, fcae408-fcae408. PubMed  Europe PubMed DOI
  11. Vrzalova,A. and Vrzal,R.
    Orchestra of ligand-activated transcription factors in the molecular symphony of SERPINE 1 / PAI-1 gene regulation
    Biochimie PubMed  Europe PubMed DOI  V
    12. 2023
  12. Afosah,D.K., Fayyad,R.M., Puliafico,V.R., Merrell,S., Langmia,E.K., Diagne,S.R., Al-Horani,R.A. and Desai,U.R.
    Homogeneous, Synthetic, Non-Saccharide Glycosaminoglycan Mimetics as Potent Inhibitors of Human Cathepsin G
    Biomolecules13, PubMed  Europe PubMed DOI  I
  13. Ferreira,G.C., Bomediano Camillo,L.M. and Sasaki,S.D.
    Structural and functional properties of rBmTI-A: A Kunitz-BPTI serine protease inhibitor with therapeutical potential
    Biochimie204, 7- PubMed  Europe PubMed DOI
  14. Kaur,P., Sethi,D., Hade,M.D., Kaur,J. and Dikshit,K.L.
    C-terminal lysine residues enhance plasminogen activation by inducing conformational flexibility and stabilization of activator complex of staphylokinase with plasmin
    Arch Biochem Biophys743, 109671-109671. PubMed  Europe PubMed DOI
  15. Moore-Lotridge,S.N., Hajdu,K.S., Hou,B.Q., Gibson,B.H.Y. and Schoenecker,J.G.
    Maintaining the balance: the critical role of plasmin activity in orthopedic surgery injury response
    J Thromb Haemost21, 2653-2665. PubMed  Europe PubMed DOI  V
  16. Yang,J., Cha,L., Wang,Y., Zhang,Q., Tang,X., Shao,J. and Duan,Z.
    L-Palmitoylcarnitine potentiates plasmin and tPA to inhibit thrombosis
    Nat Prod Bioprospect13, 48-48. PubMed  Europe PubMed DOI
    17. 2022
  17. Bryk-Wiazania,A.H., Cysewski,D., Oclon,E. and Undas,A.
    Mass-spectrometric identification of oxidative modifications in plasma-purified plasminogen: Association with hypofibrinolysis in patients with acute pulmonary embolism
    Biochem Biophys Res Commun621, 53-58. PubMed  Europe PubMed DOI
  18. Loef,E.J., Sheppard,H.M., Birch,N.P. and Dunbar,P.R.
    Plasminogen and plasmin can bind to human T cells and generate truncated CCL21 that increases dendritic cell chemotactic responses
    J Biol Chem298, 102112-102112. PubMed  Europe PubMed DOI
  19. Mehner,C., Hockla,A., Coban,M., Madden,B., Estrada,R., Radisky,D.C. and Radisky,E.S.
    Activity-based protein profiling reveals active serine proteases that drive malignancy of human ovarian clear cell carcinoma
    J Biol Chem298, 102146-102146. PubMed  Europe PubMed DOI
  20. Vasilyeva,A., Yurina,L., Ivanov,V., Azarova,D., Gavrilina,E., Indeykina,M., Bugrova,A., Kononikhin,A., Nikolaev,E. and Rosenfeld,M.
    The effect of hypochlorite- and peroxide-induced oxidation of plasminogen on damage to the structure and biological activity
    Int J Biol Macromol206, 64-73. PubMed  Europe PubMed DOI
    21. 2021
  21. Friedrich,C., Neugebauer,L., Zamora,M., Robles,J.P., Martinez de la Escalera,G., Clapp,C., Bertsch,T. and Triebel,J.
    Plasmin generates vasoinhibin-like peptides by cleaving prolactin and placental lactogen
    Mol Cell Endocrinol538, 111471-111471. PubMed  Europe PubMed DOI
  22. Heestermans,M., Naudin,C., Mailer,R.K., Konrath,S., Klaetschke,K., Jamsa,A., Frye,M., Deppermann,C., Pula,G., Kuta,P., Friese,M.A., Gelderblom,M., Sickmann,A., Preston,R.J.S., Nofer,J.R., Rose-John,S., Butler,L.M., Salomon,O., Stavrou,E.X. and Renne,T.
    Identification of the factor XII contact activation site enables sensitive coagulation diagnostics
    Nat Commun12, 5596-5596. PubMed  Europe PubMed DOI
  23. Ismail,A.A., Shaker,B.T. and Bajou,K.
    The Plasminogen-Activator Plasmin System in Physiological and Pathophysiological Angiogenesis
    Int J Mol Sci23, PubMed  Europe PubMed DOI
  24. Kryza,T., Khan,T., Lovell,S., Harrington,B.S., Yin,J., Porazinski,S., Pajic,M., Koistinen,H., Rantala,J.K., Dreyer,T., Magdolen,V., Reuning,U., He,Y., Tate,E.W. and Hooper,J.D.
    Substrate-biased activity-based probes identify proteases that cleave receptor CDCP1
    Nat Chem Biol PubMed  Europe PubMed DOI
  25. Kunnapuu,J., Bokharaie,H. and Jeltsch,M.
    Proteolytic Cleavages in the VEGF Family: Generating Diversity among Angiogenic VEGFs, Essential for the Activation of Lymphangiogenic VEGFs
    Biology (Basel)10, PubMed  Europe PubMed DOI
  26. Miszta,A., Huskens,D., Donkervoort,D., Roberts,M.J.M., Wolberg,A.S. and de Laat,B.
    Assessing Plasmin Generation in Health and Disease
    Int J Mol Sci22, PubMed  Europe PubMed DOI  V
  27. Pala,Z.R., Ernest,M., Sweeney,B., Jeong,Y.J., Pascini,T.V., Alves E Silva and Vega-Rodriguez,J.
    Beyond cuts and scrapes: plasmin in malaria and other vector-borne diseases
    Trends Parasitol PubMed  Europe PubMed DOI  V
  28. Walvekar,V.A., Ramesh,K., Jobichen,C., Kannan,M., Sivaraman,J., Kini,R.M. and Mok,Y.K.
    Crystal structure of Aedes aegypti trypsin inhibitor in complex with mu-plasmin reveals role for scaffold stability in Kazal-type serine protease inhibitor
    Protein Sci PubMed  Europe PubMed DOI
  29. Wang,M., Xie,Y. and Qin,D.
    Proteolytic cleavage of proBDNF to mBDNF in neuropsychiatric and neurodegenerative diseases
    Brain Res Bull166, 172-184. PubMed  Europe PubMed DOI
    30. 2020
  30. Ayinuola,Y.A., Brito-Robinson,T., Ayinuola,O., Beck,J.E., Cruz-Topete,D., Lee,S.W., Ploplis,V.A. and Castellino,F.J.
    Streptococcus co-opts a conformational lock in human plasminogen to facilitate streptokinase cleavage and bacterial virulence
    J Biol Chem PubMed  Europe PubMed DOI
  31. Baghban,R., Farajnia,S., Ghasemi,Y., Hoseinpoor,R., Safary,A., Mortazavi,M. and Zarghami,N.
    Mutational Analysis of Ocriplasmin to Reduce Proteolytic and Autolytic Activity in Pichia pastoris
    Biol Proced Online22, 25-25. PubMed  Europe PubMed DOI
  32. Brunet,J.G., Sharma,T., Tasneem,S., Liang,M., Wilson,M.D., Rivard,G.E. and Hayward,C.P.M.
    Thrombin generation abnormalities in Quebec platelet disorder
    Int J Lab Hematole13302-e13302. PubMed  Europe PubMed DOI  I
  33. Heissig,B., Salama,Y., Takahashi,S., Osada,T. and Hattori,K.
    The multifaceted role of plasminogen in inflammation
    Cell Signal75, 109761-109761. PubMed  Europe PubMed DOI  V
  34. Klaassen,K., Stankovic,B., Zukic,B., Kotur,N., Gasic,V., Pavlovic,S. and Stojiljkovic,M.
    Functional prediction and comparative population analysis of variants in genes for proteases and innate immunity related to SARS-CoV-2 infection
    Infect Genet Evol84, 104498-104498. PubMed  Europe PubMed DOI
  35. Marceau,F., Rivard,G.E., Gauthier,J.M., Binkley,K.E., Bonnefoy,A., Boccon-Gibod,I., Bouillet,L., Picard,M., Levesque,G., Elfassy,H.L., Bachelard,H., Hebert,J. and Bork,K.
    Measurement of Bradykinin Formation and Degradation in Blood Plasma: Relevance for Acquired Angioedema Associated With Angiotensin Converting Enzyme Inhibition and for Hereditary Angioedema Due to Factor XII or Plasminogen Gene Variants
    Front Med (Lausanne)7, 358-358. PubMed  Europe PubMed DOI  I
  36. Medcalf,R.L., Keragala,C.B. and Myles,P.S.
    Fibrinolysis and COVID-19: A plasmin paradox
    J Thromb Haemost PubMed  Europe PubMed DOI
  37. Miles,L.A., Vago,J.P., Sousa,L.P. and Parmer,R.J.
    Functions of the Plasminogen Receptor, Plg-RKT
    J Thromb Haemost PubMed  Europe PubMed DOI  V
  38. Moraes,C.T.P., Longo,J., Silva,L.B., Pimenta,D.C., Carvalho,E., Morone,M.S.L.C., da Ros,N., Serrano,S.M.T., Santos,A.C.M., Piazza,R.M.F., Barbosa,A.S. and Elias,W.P.
    Surface Protein Dispersin of Enteroaggregative Escherichia coli Binds Plasminogen That Is Converted Into Active Plasmin
    Front Microbiol11, 1222-1222. PubMed  Europe PubMed DOI
  39. Pedersen,N.B., Stolberg,C.R., Mundbjerg,L.H., Juhl,C.B., Gram,B., Funch-Jensen,P., de Maat,M.P.M., Munster,A.B. and Bladbjerg,E.M.
    Reductions in plasmin inhibitor and fibrinogen predict the improved fibrin clot lysis 6 months after obesity surgery
    Clin Obese12397-e12397. PubMed  Europe PubMed DOI
  40. Sanda,T., Yoshimura,M., Hyodo,K., Ishii,H. and Yamashita,T.
    Effects of Long-term Thrombin Inhibition (Dabigatran Etexilate) on Spontaneous Thrombolytic Activity during the Progression of Atherosclerosis in ApoE(-/-)-LDLR(-/-) Double-Knockout Mice
    Korean Circ J50, 804-816. PubMed  Europe PubMed DOI  I
  41. Seth,S., Batra,J. and Srinivasan,S.
    COVID-19: Targeting Proteases in Viral Invasion and Host Immune Response
    Front Mol Biosci7, 215-215. PubMed  Europe PubMed DOI  V
  42. Steinmetzer,T., Pilgram,O., Wenzel,B.M. and Wiedemeyer,S.J.A.
    Fibrinolysis inhibitors: potential drugs for the treatment and prevention of bleeding
    J Med Chem63, 1445-1472. PubMed  Europe PubMed DOI  I
  43. Suzuki,Y., Sano,H., Mochizuki,L., Honkura,N. and Urano,T.
    Activated platelet-based inhibition of fibrinolysis via thrombin-activatable fibrinolysis inhibitor activation system
    Blood Adv4, 5501-5511. PubMed  Europe PubMed DOI
  44. Thierry,A.R.
    Anti-protease Treatments Targeting Plasmin(ogen) and Neutrophil Elastase May Be Beneficial in Fighting COVID-19
    Physiol Rev100, 1597-1598. PubMed  Europe PubMed DOI
  45. Vadivel,K., Zaiss,A.K., Kumar,Y., Fabian,F.M., Ismail,A.E.A., Arbing,M.A., Buchholz,W.G., Velander,W.H. and Bajaj,S.P.
    Enhanced Antifibrinolytic Efficacy of a Plasmin-Specific Kunitz-Inhibitor (60-Residue Y11T/L17R with C-Terminal IEK) of Human Tissue Factor Pathway Inhibitor Type-2 Domain1
    J Clin Med9, PubMed  Europe PubMed DOI
  46. Weihs,F., Peh,A. and Dacres,H.
    A red-shifted bioluminescence resonance energy transfer (BRET) biosensing system for rapid measurement of plasmin activity in human plasma
    Anal Chim Acta1102, 99-108. PubMed  Europe PubMed DOI  A
    47. 2019
  47. Barbosa da Cruz,D., Helms,J., Aquino,L.R., Stiel,L., Cougourdan,L., Broussard,C., Chafey,P., Ries-Kautt,M., Meziani,F., Toti,F., Gaussem,P. and Angles-Cano,E.
    DNA-bound elastase of neutrophil extracellular traps degrades plasminogen, reduces plasmin formation, and decreases fibrinolysis: proof of concept in septic shock plasma
    FASEB J33, 14270-14280. PubMed  Europe PubMed DOI
  48. Swedberg,J.E., Wu,G., Mahatmanto,T., Durek,T., Caradoc-Davies,T.T., Whisstock,J.C., Law,R.H.P. and Craik,D.J.
    Highly potent and selective plasmin inhibitors based on the sunflower trypsin inhibitor-1 scaffold attenuate fibrinolysis in plasma
    J Med Chem62, 552-560. PubMed  Europe PubMed DOI
  49. Trinh,T.H.T., Kim,J., Lee,C.H. and Ryou,C.
    Non-ionic detergents Nonidet P-40 and Triton X-100 increase enzymatic activity of plasmin
    Biochem Biophys Res Commun512, 314-318. PubMed  Europe PubMed DOI
  50. Wu,G., Quek,A.J., Caradoc-Davies,T.T., Ekkel,S.M., Mazzitelli,B., Whisstock,J.C. and Law,R.H.P.
    Structural studies of plasmin inhibition
    Biochem Soc Trans47, 541-557. PubMed  Europe PubMed DOI  I
  51. Zhao,T., Houng,A. and Reed,G.L.
    Termination of bleeding by a specific anticatalytic antibody against plasmin
    J Thromb Haemost17, 1461-1469. PubMed  Europe PubMed DOI
    52. 2018
  52. Clark,C.C., Mebius,M.M., de Maat,S., Tielens,A.G.M., DE Groot,P.G., Urbanus,R.T., Fijnheer,R., Hazenberg,B.P.C., van Hellemond,J.J. and Maas,C.
    Truncation of ADAMTS13 by plasmin enhances its activity in plasma
    Thromb Haemost118, 471-479. PubMed  Europe PubMed DOI
  53. Nguyen,N.T.T., Rottgerding,F., Devraj,G., Lin,Y.P., Koenigs,A. and Kraiczy,P.
    The complement binding and inhibitory protein CbiA of Borrelia miyamotoi degrades extracellular matrix components by interacting with plasmin(ogen)
    Front Cell Infect Microbiol8, 23-23. PubMed  Europe PubMed DOI
    54. 2017
  54. Draxler,D.F., Sashindranath,M. and Medcalf,R.L.
    Plasmin: a modulator of immune function
    Semin Thromb Hemost43, 143-153. PubMed  Europe PubMed DOI
  55. Law,R.H.P., Wu,G., Leung,E.W.W., Hidaka,K., Quek,A.J., Caradoc-Davies,T.T., Jeevarajah,D., Conroy,P.J., Kirby,N.M., Norton,R.S., Tsuda,Y. and Whisstock,J.C.
    X-ray crystal structure of plasmin with tranexamic acid-derived active site inhibitors
    Blood Adv1, 766-771. PubMed  Europe PubMed DOI  S  I
  56. Schmidt,T.C., Eriksson,P.O., Gustafsson,D., Cosgrove,D., Frolund,B. and Bostrom,J.
    Discovery and evaluation of anti-fibrinolytic plasmin inhibitors derived from 5-(4-piperidyl)isoxazol-3-ol (4-PIOL)
    J Chem Inf Model57, 1703-1714. PubMed  Europe PubMed DOI  I
  57. Shimazu,H., Munakata,S., Tashiro,Y., Salama,Y., Dhahri,D., Eiamboonsert,S., Ota,Y., Onoda,H., Tsuda,Y., Okada,Y., Nakauchi,H., Heissig,B. and Hattori,K.
    Pharmacological targeting of plasmin prevents lethality in a murine model of macrophage activation syndrome
    Blood130, 59-72. PubMed  Europe PubMed DOI  T
  58. Yang,C., Wang,L., Zhang,H., Yi,Q., Wang,L., Wang,H. and Song,L.
    The first CUB-domain containing serine protease from Chlamys farreri which might be involved in larval development and immune response
    Dev Comp Immunol76, 163-168. PubMed  Europe PubMed DOI
  59. Yuan,Y., Zajicek,J., Qiu,C., Chandrahas,V., Lee,S.W., Ploplis,V.A. and Castellino,F.J.
    Conformationally organized lysine isosteres in Streptococcus pyogenes M protein mediate direct high-affinity binding to human plasminogen
    J Biol Chem292, 15016-15027. PubMed  Europe PubMed DOI
  60. Yue,S.-L., Zhou,Z.-J., Peng,Y., Lin,L.-Z., Li,T.-J., Xing,Y.-T., Wang,F.-F., Li,C.-S. and Hu,Y.
    Development and verification of dynamic chromogenic method for determination of human plasmin activity
    Chin J Biol30, 74-78.  A
    61. 2016
  61. Chen,Y.W., Yin,S., Lai,Y.J., Johnson,M.D. and Lin,C.Y.
    Plasminogen-dependent matriptase activation accelerates plasmin generation by differentiating primary human keratinocytes
    J Invest Dermatol136, 1210-1218. PubMed  Europe PubMed DOI
  62. Gonzalez-Miguel,J., Siles-Lucas,M., Kartashev,V., Morchon,R. and Simon,F.
    Plasmin in parasitic chronic infections: friend or foe?
    Trends Parasitol32, 325-335. PubMed  Europe PubMed DOI
  63. Hidaka,K., Gohda,K., Teno,N., Wanaka,K. and Tsuda,Y.
    Active site-directed plasmin inhibitors: extension on the P2 residue
    Bioorg Med Chem24, 545-553. PubMed  Europe PubMed DOI  I
  64. Hinkes,S., Wuttke,A., Saupe,S.M., Ivanova,T., Wagner,S., Knorlein,A., Heine,A., Klebe,G. and Steinmetzer,T.
    Optimization of cyclic plasmin inhibitors: from benzamidines to benzylamines
    J Med Chem59, 6370-6386. PubMed  Europe PubMed DOI  I
  65. Kakizoe,Y., Miyasato,Y., Onoue,T., Nakagawa,T., Hayata,M., Uchimura,K., Morinaga,J., Mizumoto,T., Adachi,M., Miyoshi,T., Sakai,Y., Tomita,K., Mukoyama,M. and Kitamura,K.
    A serine protease inhibitor attenuates aldosterone-induced kidney injuries via the suppression of plasmin activity
    J Pharmacol Sci132, 145-153. PubMed  Europe PubMed DOI  I
  66. Khan,M.A. and Haller,J.A.
    Ocriplasmin for treatment of vitreomacular traction: an update
    Ophthalmol Ther5, 147-159. PubMed  Europe PubMed DOI  U
  67. Lee,Y.S., Wang,N.K., Chen,Y.P., Chen,K.J., Hwang,Y.S., Lai,C.C. and Wu,W.C.
    Plasmin enzyme-assisted vitrectomy in pediatric patients with vitreoretinal diseases
    Ophthalmic Res56, 193-201. PubMed  Europe PubMed DOI  U
  68. Leung,L.L. and Morser,J.
    Plasmin as a complement C5 convertase
    EBioMedicine5, 20-21. PubMed  Europe PubMed DOI
  69. Maleki,A., Tohidi-Zand,S.R., Amirizadeh,N., Dehghan-Haghighi,J., Zanjani,H., Arish,M., Salari,A.M., Mirhosseini,S.M. and Abrishami,M.
    Intravitreal autologous plasmin prepared by urokinase for vitreolysis: a pilot study
    Eur J Ophthalmol26, 67-70. PubMed  Europe PubMed DOI
  70. Morescalchi,F., Gambicorti,E., Duse,S., Costagliola,C. and Semeraro,F.
    From the analysis of pharmacologic vitreolysis to the comprehension of ocriplasmin safety
    Expert Opin Drug Saf15, 1267-1278. PubMed  Europe PubMed DOI  U
  71. Poturnayova,A., Karpisova,I., Castillo,G., Mezo,G., Kocsis,L., Csampai,A., Keresztes,Z. and Hianik,T.
    Detection of plasmin based on specific peptide substrate using acoustic transducer
    Sens Actuators, B Chem223, 591-598. DOI  A
    72. 2015
  72. Al-Horani,R.A., Karuturi,R., White,D.T. and Desai,U.R.
    Plasmin regulation through allosteric, sulfated, small molecules
    Molecules20, 608-624. PubMed  Europe PubMed DOI
  73. Alves,N.J. and Kline,J.A.
    Comparative study on the inhibition of plasmin and delta-plasmin via benzamidine derivatives
    Biochem Biophys Res Commun457, 358-362. PubMed  Europe PubMed DOI  I
  74. Castillo,G., Pribransky,K., Mezo,G., Kocsis,L., Csampai,A., Nemeth,K., Keresztes,Z. and Hianik,T.
    Electrochemical and photometric detection of plasmin by specific peptide substrate
    Electroanalysis27, 789-798. DOI  A
  75. Foley,J.H., Peterson,E.A., Lei,V., Wan,L.W., Krisinger,M.J. and Conway,E.M.
    Interplay between fibrinolysis and complement: plasmin cleavage of iC3b modulates immune responses
    J Thromb Haemost13, 610-618. PubMed  Europe PubMed DOI
  76. Gonzalez,T., Gaultney,R.A., Floden,A.M. and Brissette,C.A.
    Escherichia coli lipoprotein binds human plasminogen via an intramolecular domain
    Front Microbiol6, 1095-1095. PubMed  Europe PubMed DOI
  77. Khoshnevis,M. and Sebag,J.
    Pharmacologic vitreolysis with Ocriplasmin: rationale for use and therapeutic potential in vitreo-retinal disorders
    BioDrugs29, 103-112. PubMed  Europe PubMed DOI  U
  78. Liu,R., Zhao,B., Zhang,Y., Gu,J., Yu,M., Song,H., Yu,M. and Mo,W.
    High-level expression, purification, and enzymatic characterization of truncated human plasminogen (Lys531-Asn791) in the methylotrophic yeast Pichia pastoris
    BMC Biotechnol15, 50-50. PubMed  Europe PubMed DOI  E
  79. Oudart,J.B., Brassart-Pasco,S., Vautrin,A., Sellier,C., Machado,C., Dupont-Deshorgue,A., Brassart,B., Baud,S., Dauchez,M., Monboisse,J.C., Harakat,D., Maquart,F.X. and Ramont,L.
    Plasmin releases the anti-tumor peptide from the NC1 domain of collagen XIX
    Oncotarget6, 3656-3668. PubMed  Europe PubMed DOI
  80. Singh,B., Al-Jubair,T., Voraganti,C., Andersson,T., Mukherjee,O., Su,Y.C., Zipfel,P. and Riesbeck,K.
    Moraxella catarrhalis binds plasminogen to evade host innate immunity
    Infect Immun83, 3458-3469. PubMed  Europe PubMed DOI
    81. 2014
  81. Al-Horani,R.A. and Desai,U.R.
    Recent advances on plasmin inhibitors for the treatment of fibrinolysis-related disorders
    Med Res Rev34, 1168-1216. PubMed  Europe PubMed DOI  V  I
  82. Bikker,F.J., Koop,G., Leusink,N.B., Nazmi,K., Kaman,W.E., Brand,H.S. and Veerman,E.C.
    Tailor made plasmin substrates as potential diagnostic tool to test for mastitis
    Vet Res Commun38, 271-277. PubMed  Europe PubMed DOI  A  P
  83. Cheng,L., Pettersen,D., Ohlsson,B., Schell,P., Karle,M., Evertsson,E., Pahlen,S., Jonforsen,M., Plowright,A.T., Bostrom,J., Fex,T., Thelin,A., Hilgendorf,C., Xue,Y., Wahlund,G., Lindberg,W., Larsson,L.O. and Gustafsson,D.
    Discovery of the fibrinolysis inhibitor AZD6564, acting via interference of a protein-protein interaction
    ACS Med Chem Lett5, 538-543. PubMed  Europe PubMed DOI  S  I
  84. Gohda,K., Fujimori,K., Teno,N., Wanaka,K. and Tsuda,Y.
    Synthetic substrates specific to activated plasmin can monitor the enzymatic functional status in situ in breast cancer cells
    Chem Biol Drug Des83, 52-57. PubMed  Europe PubMed DOI  A
  85. Hultman,K., Cortes-Canteli,M., Bounoutas,A., Richards,A.T., Strickland,S. and Norris,E.H.
    Plasmin deficiency leads to fibrin accumulation and a compromised inflammatory response in the mouse brain
    J Thromb Haemost12, 701-712. PubMed  Europe PubMed DOI  K
  86. Koyanagi,K., Narasaki,R., Yamamichi,S., Suzuki,E. and Hasumi,K.
    Mechanism of the action of SMTP-7, a novel small-molecule modulator of plasminogen activation
    Blood Coagul Fibrinolysis25, 316-321. PubMed  Europe PubMed DOI
  87. Kumar,Y., Vadivel,K., Schmidt,A.E., Ogueli,G.I., Ponnuraj,S.M., Rannulu,N., Loo,J.A., Bajaj,M.S. and Bajaj,S.P.
    Decoy plasminogen receptor containing a selective Kunitz-inhibitory domain
    Biochemistry53, 505-517. PubMed  Europe PubMed DOI
  88. Sonderegger,P. and Matsumoto-Miyai,K.
    Activity-controlled proteolytic cleavage at the synapse
    Trends Neurosci37, 413-423. PubMed  Europe PubMed DOI
  89. Teno,N., Gohda,K., Wanaka,K., Tsuda,Y., Sueda,T., Yamashita,Y. and Otsubo,T.
    Pyrrolopyrimidine-inhibitors with hydantoin moiety as spacer can explore P4/S4 interaction on plasmin
    Bioorg Med Chem22, 2339-2352. PubMed  Europe PubMed DOI  I
  90. Valapala,M., Maji,S., Borejdo,J. and Vishwanatha,J.K.
    Cell surface translocation of annexin A2 facilitates glutamate-induced extracellular proteolysis
    J Biol Chem289, 15915-15926. PubMed  Europe PubMed DOI
  91. Verhamme,I.M. and Bock,P.E.
    Rapid binding of plasminogen to streptokinase in a catalytic complex reveals a three-step mechanism
    J Biol Chem289, 28006-28018. PubMed  Europe PubMed DOI
    92. 2013
  92. Aguda,R., Caronna,A., Hunt,J., Koepf,E., Lindsay,M., Miller,C., Rebbeor,J., Silverstein,R., Stokes,K. and Zimmerman,T.
    Production and purification of TAL6003: a novel version of the protease plasmin
    Protein Expr Purif88, 41-46. PubMed  Europe PubMed DOI  U
  93. Aneja,R., Datt,M., Yadav,S. and Sahni,G.
    Multiple exosites distributed across the three domains of streptokinase co-operate to generate high catalytic rates in the streptokinase-plasmin activator complex
    Biochemistry52, 8957-8968. PubMed  Europe PubMed DOI
  94. Hoffmann,D.C., Willenborg,S., Koch,M., Zwolanek,D., Muller,S., Becker,A.K., Metzger,S., Ehrbar,M., Kurschat,P., Hellmich,M., Hubbell,J.A. and Eming,S.A.
    Proteolytic processing regulates placental growth factor activities
    J Biol Chem288, 17976-17989. PubMed  Europe PubMed DOI  P
  95. Law,R.H., Abu-Ssaydeh,D. and Whisstock,J.C.
    New insights into the structure and function of the plasminogen/plasmin system
    Curr Opin Struct Biol23, 836-841. PubMed  Europe PubMed DOI
  96. Millers,E.K., Johnson,L.A., Birrell,G.W., Masci,P.P., Lavin,M.F., de Jersey,J. and Guddat,L.W.
    The structure of human microplasmin in complex with textilinin-1, an aprotinin-like inhibitor from the Australian brown snake
    PLoS ONE8, e54104-e54104. PubMed  Europe PubMed DOI  S
  97. Saupe,S.M., Leubner,S., Betz,M., Klebe,G. and Steinmetzer,T.
    Development of new cyclic plasmin inhibitors with excellent potency and selectivity
    J Med Chem56, 820-831. PubMed  Europe PubMed DOI  I
  98. Tse,L.V., Marcano,V.C., Huang,W., Pocwierz,M.S. and Whittaker,G.R.
    Plasmin-mediated activation of pandemic H1N1 influenza virus hemagglutinin is independent of the viral neuraminidase
    J Virol87, 5161-5169. PubMed  Europe PubMed DOI
    99. 2012
  99. Barthel,D., Schindler,S. and Zipfel,P.F.
    Plasminogen is a complement inhibitor
    J Biol Chem287, 18831-18842. PubMed  Europe PubMed DOI
  100. Canas,O., Parra,A.Q. and Ramirez,L.F.A.
    Porcine plasmin: determination of kinetic parameters and comparison with human plasmin
    Iatreia25, 111-119.
  101. Castellino,F.J.
    Plasmin
    [ISSN:978-0-12-407742-3]3, 2958-2968. DOI
  102. Deryugina,E.I. and Quigley,J.P.
    Cell surface remodeling by plasmin: a new function for an old enzyme
    J Biomed Biotechnol2012, 564259-564259. PubMed  Europe PubMed DOI
  103. Gohda,K., Teno,N., Wanaka,K. and Tsuda,Y.
    Predicting subsite interactions of plasmin with substrates and inhibitors through computational docking analysis
    J Enzyme Inhib Med Chem27, 571-577. PubMed  Europe PubMed DOI  P  I
  104. Haerteis,S., Krappitz,M., Diakov,A., Krappitz,A., Rauh,R. and Korbmacher,C.
    Plasmin and chymotrypsin have distinct preferences for channel activating cleavage sites in the gamma subunit of the human epithelial sodium channel
    J Gen Physiol140, 375-389. PubMed  Europe PubMed DOI  P
  105. Kawao,N., Nagai,N., Tamura,Y., Horiuchi,Y., Okumoto,K., Okada,K., Suzuki,Y., Umemura,K., Yano,M., Ueshima,S., Kaji,H. and Matsuo,O.
    Urokinase-type plasminogen activator and plasminogen mediate activation of macrophage phagocytosis during liver repair in vivo
    Thromb Haemost107, 749-759. PubMed  Europe PubMed DOI  K
  106. Koch,T.K., Reuter,M., Barthel,D., Bohm,S., van den Elsen,J., Kraiczy,P., Zipfel,P.F. and Skerka,C.
    Staphylococcus aureus proteins Sbi and Efb recruit human plasmin to degrade complement C3 and C3b
    PLoS ONE7, e47638-e47638. PubMed  Europe PubMed DOI
  107. Law,R.H., Caradoc-Davies,T., Cowieson,N., Horvath,A.J., Quek,A.J., Encarnacao,J.A., Steer,D., Cowan,A., Zhang,Q., Lu,B.G., Pike,R.N., Smith,A.I., Coughlin,P.B. and Whisstock,J.C.
    The X-ray crystal structure of full-length human plasminogen
    Cell Rep1, 185-190. PubMed  Europe PubMed DOI  S
  108. Saupe,S.M. and Steinmetzer,T.
    A new strategy for the development of highly potent and selective plasmin inhibitors
    J Med Chem55, 1171-1180. PubMed  Europe PubMed DOI  I
  109. Singh,S., Ashish and Dikshit,K.L.
    Pro42 and Val45 of staphylokinase modulate intermolecular interactions of His43-Tyr44 pair and specificity of staphylokinase-plasmin activator complex
    FEBS Lett586, 653-658. PubMed  Europe PubMed DOI
  110. Svenningsen,P., Skott,O. and Jensen,B.L.
    Proteinuric diseases with sodium retention: is plasmin the link?
    Clin Exp Pharmacol Physiol39, 117-124. PubMed  Europe PubMed DOI
  111. Swedberg,J.E. and Harris,J.M.
    Natural and engineered plasmin inhibitors: applications and design strategies
    Chembiochem13, 336-348. PubMed  Europe PubMed DOI  V  I
  112. Syrovets,T., Lunov,O. and Simmet,T.
    Plasmin as a proinflammatory cell activator
    J Leukoc Biol92, 509-519. PubMed  Europe PubMed DOI  V
  113. Teno,N., Otsubo,T., Gohda,K., Wanaka,K., Sueda,T., Ikeda,K., Hijikata-Okunomiya,A. and Tsuda,Y.
    Synthesis and evaluation of tripeptidic plasmin inhibitors with nitrile as warhead
    J Pept Sci18, 620-625. PubMed  Europe PubMed DOI  I
  114. Xue,Y., Bodin,C. and Olsson,K.
    Crystal structure of the native plasminogen reveals an activation-resistant compact conformation
    J Thromb Haemost10, 1385-1396. PubMed  Europe PubMed DOI  S
    115. 2011
  115. Brauer,R., Beck,I.M., Roderfeld,M., Roeb,E. and Sedlacek,R.
    Matrix metalloproteinase-19 inhibits growth of endothelial cells by generating angiostatin-like fragments from plasminogen
    BMC Biochem12, 38-38. PubMed  Europe PubMed DOI
  116. Canas,B.O., Quijano,P.A. and Arbelaez,R.F.
    Activation and comparative kinetics of Ovis aries plasmin with human plasmin
    Rev MVZ Cordoba16, 2364-2371.
  117. Dahiya,M., Singh,S., Rajamohan,G., Sethi,D., Ashish and Dikshit,K.L.
    Intermolecular interactions in staphylokinase-plasmin(ogen) bimolecular complex: function of His43 and Tyr44
    FEBS Lett585, 1814-1820. PubMed  Europe PubMed DOI
  118. Laha,M., Panizzi,P., Nahrendorf,M. and Bock,P.E.
    Engineering streptokinase for generation of active site-labeled plasminogen analogs
    Anal Biochem415, 105-115. PubMed  Europe PubMed DOI
  119. Marder,V.J.
    Historical perspective and future direction of thrombolysis research: the re-discovery of plasmin
    J Thromb Haemost9 Suppl 1, 364-373. PubMed  Europe PubMed DOI  U
  120. Moroy,G., Bourguet,E., Decarme,M., Sapi,J., Alix,A.J., Hornebeck,W. and Lorimier,S.
    Inhibition of human leukocyte elastase, plasmin and matrix metalloproteinases by oleic acid and oleoyl-galardin derivative(s)
    Biochem Pharmacol81, 626-635. PubMed  Europe PubMed DOI  I
  121. Schaller,J. and Gerber,S.S.
    The plasmin-antiplasmin system: structural and functional aspects
    Cell Mol Life Sci68, 785-801. PubMed  Europe PubMed DOI  V
  122. Swedberg,J.E. and Harris,J.M.
    Plasmin substrate binding site cooperativity guides the design of potent peptide aldehyde inhibitors
    Biochemistry50, 8454-8462. PubMed  Europe PubMed DOI  I
  123. Teno,N., Gohda,K., Wanaka,K., Sueda,T. and Tsuda,Y.
    Identification of novel plasmin inhibitors possessing nitrile moiety as warhead
    Bioorg Med Chem Lett21, 6305-6309. PubMed  Europe PubMed DOI  I
  124. Venkatraman,L., Li,H., Dewey,C.F., Jr., White,J.K., Bhowmick,S.S., Yu,H. and Tucker-Kellogg,L.
    Steady states and dynamics of urokinase-mediated plasmin activation in silico and in vitro
    Biophys J101, 1825-1834. PubMed  Europe PubMed DOI
  125. Wu,W.C., Chen,C.C., Liu,C.H., Wang,N.K., Chen,K.J., Chen,T.L., Hwang,Y.S., Li,L.M. and Lai,C.C.
    Plasmin treatment accelerates vascular endothelial growth factor clearance from rabbit eyes
    Invest Ophthalmol Vis Sci52, 6162-6167. PubMed  Europe PubMed DOI  U
  126. Yamamoto,H., Ben,S., Saitoh,S., Kamata,K., Iguchi,K. and Hoshino,M.
    Plasmin: its role in the extracellular processing of progalanin in tumor tissue
    Protein Pept Lett18, 1204-1211. PubMed  Europe PubMed DOI
    127. 2010
  127. Dejouvencel,T., Doeuvre,L., Lacroix,R., Plawinski,L., Dignat-George,F., Lijnen,H.R. and Angles-Cano,E.
    Fibrinolytic cross-talk: a new mechanism for plasmin formation
    Blood115, 2048-2056. PubMed  Europe PubMed DOI
  128. Hoover-Plow,J.
    Does plasmin have anticoagulant activity?
    Vasc Health Risk Manag6, 199-205. PubMed  Europe PubMed
  129. Ismail,B. and Nielsen,S.S.
    Invited review: Plasmin protease in milk: current knowledge and relevance to dairy industry
    J Dairy Sci93, 4999-5009. PubMed  Europe PubMed DOI
  130. Iwaki,T., Malinverno,C., Smith,D., Xu,Z., Liang,Z., Ploplis,V.A. and Castellino,F.J.
    The generation and characterization of mice expressing a plasmin-inactivating active site mutation
    J Thromb Haemost8, 2341-2344. PubMed  Europe PubMed DOI  K
  131. Marder,V.J., Manyak,S., Gruber,T., Goyal,A., Moreno,G., Hunt,J., Bromirski,J., Scuderi,P., Petteway,S.R., Jr. and Novokhatny,V.
    Haemostatic safety of a unique recombinant plasmin molecule lacking kringles 2-5
    Thromb Haemost104, 780-787. PubMed  Europe PubMed DOI  U
  132. Marder,V.J., Jahan,R., Gruber,T., Goyal,A. and Arora,V.
    Thrombolysis with plasmin: implications for stroke treatment
    Stroke41, S45-S49. PubMed  Europe PubMed DOI  U
    133. 2009
  133. Aneja,R., Datt,M., Singh,B., Kumar,S. and Sahni,G.
    Identification of a new exosite involved in catalytic turnover by the streptokinase-plasmin activator complex during human plasminogen activation
    J Biol Chem284, 32642-32650. PubMed  Europe PubMed DOI
  134. Hofmann,S.C., Voith,U., Schonau,V., Sorokin,L., Bruckner-Tuderman,L. and Franzke,C.W.
    Plasmin plays a role in the in vitro generation of the linear IgA dermatosis antigen LADB97
    J Invest Dermatol129, 1730-1739. PubMed  Europe PubMed DOI
  135. Nogami,K., Nishiya,K., Saenko,E.L., Takeyama,M., Ogiwara,K., Yoshioka,A. and Shima,M.
    Identification of plasmin-interactive sites in the light chain of factor VIII responsible for proteolytic cleavage at Lys36
    J Biol Chem284, 6934-6945. PubMed  Europe PubMed DOI  P
  136. Ohtsuka,K., Maekawa,I., Waki,M. and Takenaka,S.
    Electrochemical assay of plasmin activity and its kinetic analysis
    Anal Biochem385, 293-299. PubMed  Europe PubMed DOI  A
  137. Purwin,M., Bruzgo,I., Markowska,A. and Midura-Nowaczek,K.
    Short peptides containing L-lysine and epsilon-aminocaproic acid as potential plasmin inhibitors
    Pharmazie64, 765-767. PubMed  Europe PubMed DOI  I
  138. Svenningsen,P., Uhrenholt,T.R., Palarasah,Y., Skjodt,K., Jensen,B.L. and Skott,O.
    Prostasin-dependent activation of epithelial Na+ channels by low plasmin concentrations
    Am J Physiol Regul Integr Comp Physiol297, R1733-R1741. PubMed  Europe PubMed DOI
  139. Yuan,H., Vance,K.M., Junge,C.E., Geballe,M.T., Snyder,J.P., Hepler,J.R., Yepes,M., Low,C.M. and Traynelis,S.F.
    The serine protease plasmin cleaves the amino-terminal domain of the NR2A subunit to relieve zinc inhibition of the N-methyl-D-aspartate receptors
    J Biol Chem284, 12862-12873. PubMed  Europe PubMed DOI  P
  140. Zhang,D., Jiang,S., Ma,J., Jiang,J., Pan,D. and Xu,X.
    Molecular cloning, characterization and expression analysis of a clip-domain serine protease from pearl oyster Pinctada fucata
    Fish Shellfish Immunol26, 662-668. PubMed  Europe PubMed DOI
    141. 2008
  141. Gray,K. and Ellis,V.
    Activation of pro-BDNF by the pericellular serine protease plasmin
    FEBS Lett582, 907-910. PubMed  Europe PubMed DOI  P
  142. Hunt,J.A., Petteway,S.R., Jr., Scuderi,P. and Novokhatny,V.
    Simplified recombinant plasmin: production and functional comparison of a novel thrombolytic molecule with plasma-derived plasmin
    Thromb Haemost100, 413-419. PubMed  Europe PubMed DOI  E
  143. Lei,H., Velez,G., Hovland,P., Hirose,T. and Kazlauskas,A.
    Plasmin is the major protease responsible for processing PDGF-C in the vitreous of patients with proliferative vitreoretinopathy
    Invest Ophthalmol Vis Sci49, 42-48. PubMed  Europe PubMed DOI  T
  144. Marder,V.J.
    Pre-clinical studies of plasmin: superior benefit-to-risk ratio of plasmin compared to tissue plasminogen activator
    Thromb Res122 Suppl 3, S9-S9. PubMed  Europe PubMed DOI  U
  145. Passero,C.J., Mueller,G.M., Rondon-Berrios,H., Tofovic,S.P., Hughey,R.P. and Kleyman,T.R.
    Plasmin activates epithelial Na+ channels by cleaving the gamma subunit
    J Biol Chem283, 36586-36591. PubMed  Europe PubMed DOI
  146. Tanka-Salamon,A., Tenekedjiev,K., Machovich,R. and Kolev,K.
    Suppressed catalytic efficiency of plasmin in the presence of long-chain fatty acids. Identification of kinetic parameters from continuous enzymatic assay with Monte Carlo simulation
    FEBS J275, 1274-1282. PubMed  Europe PubMed DOI  A  I
    147. 2007
  147. Devy,L., Rabbani,S.A., Stochl,M., Ruskowski,M., Mackie,I., Naa,L., Toews,M., van Gool,R., Chen,J., Ley,A., Ladner,R.C., Dransfield,D.T. and Henderikx,P.
    PEGylated DX-1000: pharmacokinetics and antineoplastic activity of a specific plasmin inhibitor
    Neoplasia9, 927-937. PubMed  Europe PubMed DOI
  148. Gladysheva,I.P., Sazonova,I.Y., Houng,A., Hedstrom,L. and Reed,G.L.
    Regulation of nonproteolytic active site formation in plasminogen
    Biochemistry46, 8879-8887. PubMed  Europe PubMed DOI
  149. Grundy,J.E., Hancock,M.A., Meixner,S.C., MacKenzie,R.C., Koschinsky,M.L. and Pryzdial,E.L.
    Plasminogen binds to plasmin-modulated factor Xa by Ca (2+) - and C-terminal lysine-dependent and -independent interactions
    Thromb Haemost97, 38-44. PubMed  Europe PubMed DOI
  150. Markowska,A., Midura-Nowaczek,K. and Bruzgo,I.
    Low molecular peptides as potential inhibitors of plasmin
    Acta Pol Pharm64, 355-358. PubMed  Europe PubMed  I
  151. Nogami,K., Shima,M., Matsumoto,T., Nishiya,K., Tanaka,I. and Yoshioka,A.
    Mechanisms of plasmin-catalyzed inactivation of factor VIII: a crucial role for proteolytic cleavage at Arg336 responsible for plasmin-catalyzed factor VIII inactivation
    J Biol Chem282, 5287-5295. PubMed  Europe PubMed DOI  P
  152. [YEAR:14-2-2007]Sheehan,J.J., Zhou,C., Gravanis,I., Rogove,A.D., Wu,Y.P., Bogenhagen,D.F. and Tsirka,S.E.
    Proteolytic activation of monocyte chemoattractant protein-1 by plasmin underlies excitotoxic neurodegeneration in mice
    J Neurosci27, 1738-1745. PubMed  Europe PubMed DOI  K
  153. [YEAR:28-1-2007]Stillfried,G.E., Saunders,D.N. and Ranson,M.
    Plasminogen binding and activation at the breast cancer cell surface: the integral role of urokinase activity
    Breast Cancer Res9, R14-R14. PubMed  Europe PubMed DOI
    154. 2006
  154. Rizzo,S., Pellegrini,G., Benocci,F., Belting,C., Baicchi,U. and Vispi,M.
    Autologous plasmin for pharmacologic vitreolysis prepared 1 hour before surgery
    Retina26, 792-796. PubMed  Europe PubMed DOI  U
  155. [YEAR:11-9-2006]Xue,F. and Seto,C.T.
    Structure-activity studies of cyclic ketone inhibitors of the serine protease plasmin: design, synthesis, and biological activity
    Bioorg Med Chem14, 8467-8487. PubMed  Europe PubMed DOI  I
    156. 2005
  156. Castellino,F.J. and Ploplis,V.A.
    Structure and function of the plasminogen/plasmin system
    Thromb Haemost93, 647-654. PubMed  Europe PubMed DOI  V
  157. Comer,M.B., Cackett,K.S., Gladwell,S., Wood,L.M. and Dawson,K.M.
    Thrombolytic activity of BB-10153, a thrombin-activatable plasminogen
    J Thromb Haemost3, 146-153. PubMed  Europe PubMed DOI
  158. Ho-Tin-Noe,B., Rojas,G., Vranckx,R., Lijnen,H.R. and Angles-Cano,E.
    Functional hierarchy of plasminogen kringles 1 and 4 in fibrinolysis and plasmin-induced cell detachment and apoptosis
    FEBS J272, 3387-3400. PubMed  Europe PubMed DOI
  159. Kwon,M., Yoon,C.S., Jeong,W., Rhee,S.G. and Waisman,D.M.
    Annexin A2-S100A10 heterotetramer, a novel substrate of thioredoxin
    J Biol Chem280, 23584-23592. PubMed  Europe PubMed DOI
  160. [YEAR:23-12-2005]Quagraine,M.O., Tan,F., Tamei,H., Erdos,E.G. and Skidgel,R.A.
    Plasmin alters the activity and quaternary structure of human plasma carboxypeptidase N
    Biochem J388, 81-91. PubMed  Europe PubMed DOI
  161. [YEAR:12-8-2005]Warejcka,D.J. and Twining,S.S.
    Specific conformational changes of plasminogen induced by chloride ions, 6-aminohexanoic acid and benzamidine, but not the overall openness of plasminogen regulate, production of biologically active angiostatins
    Biochem J392, 703-712. PubMed  Europe PubMed DOI  I
  162. [YEAR:14-10-2005]Xue,F. and Seto,C.T.
    A comparison of cyclohexanone and tetrahydro-4H-thiopyran-4-one 1,1-dioxide as pharmacophores for the design of peptide-based inhibitors of the serine protease plasmin
    J Org Chem70, 8309-8321. PubMed  Europe PubMed DOI  I
  163. [YEAR:3-11-2005]Xue,F. and Seto,C.T.
    Selective inhibitors of the serine protease plasmin: probing the S3 and S3' subsites using a combinatorial library
    J Med Chem48, 6908-6917. PubMed  Europe PubMed DOI  I
    164. 2004
  164. [YEAR:10-9-2004]Beaufort,N., Leduc,D., Rousselle,J.C., Namane,A., Chignard,M. and Pidard,D.
    Plasmin cleaves the juxtamembrane domain and releases truncated species of the urokinase receptor (CD87) from human bronchial epithelial cells
    FEBS Lett574, 89-94. PubMed  Europe PubMed DOI
  165. [YEAR:27-9-2004]Boxrud,P.D., Verhamme,I.M. and Bock,P.E.
    Resolution of conformational activation in the kinetic mechanism of plasminogen activation by streptokinase
    J Biol Chem279, 36633-36641. PubMed  Europe PubMed DOI
  166. Castellino,F.J.
    Plasmin
    [ISSN:0-12-079610-4]2, 1692-1699.  V
  167. [YEAR:29-10-2004]Ehinger,S., Schubert,W.D., Bergmann,S., Hammerschmidt,S. and Heinz,D.W.
    Plasmin(ogen)-binding alpha-enolase from Streptococcus pneumoniae: crystal structure and evaluation of plasmin(ogen)-binding sites
    J Mol Biol343, 997-1005. PubMed  Europe PubMed DOI
  168. Gandorfer,A., Rohleder,M., Sethi,C., Eckle,D., Welge-Lussen,U., Kampik,A., Luthert,P. and Charteris,D.
    Posterior vitreous detachment induced by microplasmin
    Invest Ophthalmol Vis Sci45, 641-647. PubMed  Europe PubMed DOI
  169. Novokhatny,V.V., Jesmok,G.J., Landskroner,K.A., Marder,V.J. and Zimmerman,T.P.
    Locally delivered plasmin: why should it be superior to plasminogen activators for direct thrombolysis?
    Trends Pharmacol Sci25, 72-75. PubMed  Europe PubMed DOI  U
  170. Ohyama,S., Harada,T., Chikanishi,T., Miura,Y. and Hasumi,K.
    Nonlysine-analog plasminogen modulators promote autoproteolytic generation of plasmin(ogen) fragments with angiostatin-like activity
    Eur J Biochem271, 809-820. PubMed  Europe PubMed DOI
  171. Samara,G.J., Schaffner,A.D., Eisenstat,J. and Nguyen,H.L.
    The effects of the plasminogen pathway on scar tissue formation
    Laryngoscope114, 46-49. PubMed  Europe PubMed DOI  K
  172. [YEAR:27-8-2004]Sun,H., Ringdahl,U., Homeister,J.W., Fay,W.P., Engleberg,N.C., Yang,A.Y., Rozek,L.S., Wang,X., Sjobring,U. and Ginsburg,D.
    Plasminogen is a critical host pathogenicity factor for group A streptococcal infection
    Science305, 1283-1286. PubMed  Europe PubMed DOI
  173. Syrovets,T. and Simmet,T.
    Novel aspects and new roles for the serine protease plasmin
    Cell Mol Life Sci61, 873-885. PubMed  Europe PubMed DOI
  174. [YEAR:1-8-2004]Terzyan,S., Wakeham,N., Zhai,P., Rodgers,K. and Zhang,X.C.
    Characterization of Lys-698-to-Met substitution in human plasminogen catalytic domain
    Proteins56, 277-284. PubMed  Europe PubMed DOI
  175. [YEAR:24-9-2004]Ward,P.N., Field,T.R., Rosey,E.L., Abu-Median,A.B., Lincoln,R.A. and Leigh,J.A.
    Complex interactions between bovine plasminogen and streptococcal plasminogen activator PauA
    J Mol Biol342, 1101-1114. PubMed  Europe PubMed DOI
    176. 2003
  176. [YEAR:15-4-2003]Behrendt,N., List,K., Andreasen,P.A. and Dano,K.
    The pro-urokinase plasminogen-activation system in the presence of serpin-type inhibitors and the urokinase receptor: rescue of activity through reciprocal pro-enzyme activation
    Biochem J371, 277-287. PubMed  Europe PubMed DOI
  177. Guinn,L. and Doctor,V.M.
    Mechanism of the stimulatory effect of 6-aminohexanoic acid on plasminogen activation by streptokinase or tissue plasminogen activator: the role of chloride
    Eur J Drug Metab Pharmacokinet28, 315-320. PubMed  Europe PubMed
  178. [YEAR:31-10-2003]Heinemann,F.S., Korza,G. and Ozols,J.
    A plasminogen-like protein selectively degrades stearoyl-CoA desaturase in liver microsomes
    J Biol Chem278, 42966-42975. PubMed  Europe PubMed DOI
  179. Miles,L.A., Castellino,F.J. and Gong,Y.
    Critical role for conversion of Glu-plasminogen to Lys-plasminogen for optimal stimulation of plasminogen activation on cell surfaces
    Trends Cardiovasc Med13, 21-30. PubMed  Europe PubMed DOI
  180. Nowak,P. and Zgirski,A.
    Effects of metal ions on activity of plasmin
    Biol Trace Elem Res93, 87-94. PubMed  Europe PubMed DOI
  181. Rakic,J.M., Maillard,C., Jost,M., Bajou,K., Masson,V., Devy,L., Lambert,V., Foidart,J.M. and Noel,A.
    Role of plasminogen activator-plasmin system in tumor angiogenesis
    Cell Mol Life Sci60, 463-473. PubMed  Europe PubMed DOI
  182. van der Laan,W.H., Ronday,H.K., TeKoppele,J.M., Breedveld,F.C., Huizinga,T.W. and Verheijen,J.H.
    No therapeutic effect of plasmin antagonist tranexamic acid in rheumatoid arthritis. A double-blind placebo-controlled pilot study
    Clin Exp Rheumatol21, 359-362. PubMed  Europe PubMed  I
  183. [YEAR:22-2-2002]Abato,P., Yuen,C.M., Cubanski,J.Y. and Seto,C.T.
    Inhibitors of plasmin that extend into both the S and S' binding sites: Cooperative interactions between S1 and S2
    J Org Chem67, 1184-1191. PubMed  Europe PubMed DOI  I
    184. 2002
  184. [YEAR:6-9-2002]Burysek,L., Syrovets,T. and Simmet,T.
    The serine protease plasmin triggers expression of MCP-1 and CD40 in human primary monocytes via activation of p38 MAPK and Janus kinase (JAK)/STAT signaling pathways
    J Biol Chem277, 33509-33517. PubMed  Europe PubMed DOI
  185. Lapchak,P.A., Araujo,D.M., Pakola,S., Song,D., Wei,J. and Zivin,J.A.
    Microplasmin: a novel thrombolytic that improves behavioral outcome after embolic strokes in rabbits
    Stroke33, 2279-2284. PubMed  Europe PubMed DOI
  186. [YEAR:13-9-2002]Tarui,T., Majumdar,M., Miles,L.A., Ruf,W. and Takada,Y.
    Plasmin-induced migration of endothelial cells. A potential target for the anti-angiogenic action of angiostatin
    J Biol Chem277, 33564-33570. PubMed  Europe PubMed DOI
    187. 2001
  187. [YEAR:13-7-2001]Boxrud,P.D., Verhamme,I.M., Fay,W.P. and Bock,P.E.
    Streptokinase triggers conformational activation of plasminogen through specific interactions of the amino-terminal sequence and stabilizes the active zymogen conformation
    J Biol Chem276, 26084-26089. PubMed  Europe PubMed DOI
  188. [YEAR:1-6-2001]Gong,Y., Kim,S.O., Felez,J., Grella,D.K., Castellino,F.J. and Miles,L.A.
    Conversion of Glu-plasminogen to Lys-plasminogen is necessary for optimal stimulation of plasminogen activation on the endothelial cell surface
    J Biol Chem276, 19078-19083. PubMed  Europe PubMed DOI
  189. [YEAR:6-7-2001]Jiang,Q., Taupenot,L., Mahata,S.K., Mahata,M., O'Connor,D.T., Miles,L.A. and Parmer,R.J.
    Proteolytic cleavage of chromogranin A (CgA) by plasmin. Selective liberation of a specific bioactive CgA fragment that regulates catecholamine release
    J Biol Chem276, 25022-25029. PubMed  Europe PubMed DOI
  190. [YEAR:23-3-2001]Kassam,G., Kwon,M., Yoon,C.S., Graham,K.S., Young,M.K., Gluck,S. and Waisman,D.M.
    Purification and characterization of A61. An angiostatin-like plasminogen fragment produced by plasmin autodigestion in the absence of sulfhydryl donors
    J Biol Chem276, 8924-8933. PubMed  Europe PubMed DOI
  191. [YEAR:27-3-2001]Kornblatt,J.A., Rajotte,I. and Heitz,F.
    Reaction of canine plasminogen with 6-aminohexanoate: A thermodynamic study combining fluorescence, circular dichroism, and isothermal titration calorimetry
    Biochemistry40, 3639-3647. PubMed  Europe PubMed DOI
  192. Lee,A.Y.Y., Fredenburgh,J.C., Stewart,R.J., Rischke,J.A. and Weitz,J.I.
    Like fibrin, (DD)E, the major degradation product of crosslinked fibrin, protects plasmin from inhibition by alpha2-antiplasmin
    Thromb Haemost85, 502-508. PubMed  Europe PubMed
  193. Marder,V.J., Landskroner,K., Novokhatny,V., Zimmerman,T.P., Kong,M., Kanouse,J.J. and Jesmok,G.
    Plasmin induces local thrombolysis without causing hemorrhage: A comparison with tissue plasminogen activator in the rabbit
    Thromb Haemost86, 739-745. PubMed  Europe PubMed
  194. [YEAR:13-4-2001]Said,B., HaMai,D. and Matsumoto,D.C.
    Purification of follicular regulatory protein: Possible plasminogen identity
    Biochem Biophys Res Commun282, 1045-1052. PubMed  Europe PubMed DOI
  195. Vakili,J., Standker,L., Detheux,M., Vassart,G., Forssmann,W.G. and Parmentier,M.
    Urokinase plasminogen activator and plasmin efficiently convert hemofiltrate CC chemokine 1 into its active [9-74] processed variant
    J Immunol167, 3406-3413. PubMed  Europe PubMed  P
    196. 2000
  196. Creemers,E., Cleutjens,J., Smits,J., Heymans,S., Moons,L., Collen,D., Daemen,M. and Carmeliet,P.
    Disruption of the plasminogen gene in mice abolishes wound healing after myocardial infarction
    Am J Pathol156, 1865-1873. PubMed  Europe PubMed DOI  K
  197. [YEAR:5-7-2000]Harris,J.L., Backes,B.J., Leonetti,F., Mahrus,S., Ellman,J.A. and Craik,C.S.
    Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries
    Proc Natl Acad Sci U S A97, 7754-7759. PubMed  Europe PubMed DOI  P
  198. Okada,Y., Tsuda,Y., Tada,M., Wanaka,K., Okamoto,U., Hijikata-Okunomiya,A. and Okamoto,S.
    Development of potent and selective plasmin and plasma kallikrein inhibitors and studies on the structure-activity relationship
    Chem Pharm Bull (Tokyo)48, 1964-1972. PubMed  Europe PubMed  I
  199. Parmer,R.J., Mahata,M., Gong,Y., Mahata,S.K., Jiang,Q., O'Connor,D.T., Xi,X.P. and Miles,L.A.
    Processing of chromogranin A by plasmin provides a novel mechanism for regulating catecholamine secretion
    J Clin Invest106, 907-915. PubMed  Europe PubMed DOI
  200. Parry,M.A., Zhang,X.C. and Bode,I.
    Molecular mechanisms of plasminogen activation: bacterial cofactors provide clues
    Trends Biochem Sci25, 53-59. PubMed  Europe PubMed DOI
  201. Ploplis,V.A. and Castellino,F.J.
    Nonfibrinolytic functions of plasminogen
    Methods21, 103-110. PubMed  Europe PubMed DOI
  202. [YEAR:1-2-2000]Samis,J.A., Ramsey,G.D., Walker,J.B., Nesheim,M.E. and Giles,A.R.
    Proteolytic processing of human coagulation factor IX by plasmin
    Blood95, 943-951. PubMed  Europe PubMed
  203. van der Laan,W.H., Pap,T., Ronday,H.K., Grimbergen,J.M., Huisman,L.G., TeKoppele,J.M., Breedveld,F.C., Gay,R.E., Gay,S., Huizinga,T.W., Verheijen,J.H. and Quax,P.H.
    Cartilage degradation and invasion by rheumatoid synovial fibroblasts is inhibited by gene transfer of a cell surface-targeted plasmin inhibitor
    Arthritis Rheum43, 1710-1718. PubMed  Europe PubMed DOI
  204. Wang,S., Reed,G.L. and Hedstrom,L.
    Zymogen activation in the streptokinase-plasminogen complex. Ile1 is required for the formation of a functional active site
    Eur J Biochem267, 3994-4001. PubMed  Europe PubMed DOI
  205. Wang,X., Terzyan,S., Tang,J., Loy,J.A., Lin,X. and Zhang,X.C.
    Human plasminogen catalytic domain undergoes an unusual conformational change upon activation
    J Mol Biol295, 903-914. PubMed  Europe PubMed DOI  S
    206. 1999
  206. Nilsen,S.L. and Castellino,F.J.
    Expression of human plasminogen in Drosophila Schneider S2 cells
    Protein Expr Purif16, 136-143. PubMed  Europe PubMed DOI  E
  207. [YEAR:24-8-1999]Peisach,E., Wang,J., de los Santos,T., Reich,E. and Ringe,D.
    Crystal structure of the proenzyme domain of plasminogen
    Biochemistry38, 11180-11188. PubMed  Europe PubMed DOI  S
  208. Pryzdial,E.L., Lavigne,N., Dupuis,N. and Kessler,G.E.
    Plasmin converts factor X from coagulation zymogen to fibrinolysis cofactor
    J Biol Chem274, 8500-8505. PubMed  Europe PubMed DOI
  209. [YEAR:19-11-1999]Santala,A., Saarinen,J., Kovanen,P. and Kuusela,P.
    Activation of interstitial collagenase, MMP-1, by Staphylococcus aureus cells having surface-bound plasmin: a novel role of plasminogen receptors of bacteria
    FEBS Lett461, 153-156. PubMed  Europe PubMed DOI
    210. 1998
  210. [YEAR:15-7-1998]Farina,A.R., Tacconelli,A., Teti,A., Gulino,A. and Mackay,A.R.
    Tissue inhibitor of metalloproteinase-2 protection of matrix metalloproteinase-2 from degradation by plasmin is reversed by divalent cation chelator EDTA and the bisphosphonate alendronate
    Cancer Res58, 2957-2960. PubMed  Europe PubMed
  211. [YEAR:5-5-1998]Jespers,L., Van Herzeele,N., Lijnen,H.R., Van Hoef,B., De Maeyer,M., Collen,D. and Lasters,I.
    Arginine 719 in human plasminogen mediates formation of the staphylokinase:plasmin activator complex
    Biochemistry37, 6380-6386. PubMed  Europe PubMed DOI
  212. Lijnen,H.R., Silence,J., Lemmens,G., Frederix,L. and Collen,D.
    Regulation of gelatinase activity in mice with targeted inactivation of components of the plasminogen/plasmin system
    Thromb Haemost79, 1171-1176. PubMed  Europe PubMed
  213. Ohkura,N., Hagihara,Y., Yoshimura,T., Goto,Y. and Kato,H.
    Plasmin can reduce the function of human beta2 glycoprotein I by cleaving domain V into a nicked form
    Blood91, 4173-4179. PubMed  Europe PubMed  P
  214. Parry,M.A., Fernandez-Catalan,C., Bergner,A., Huber,R., Hopfner,K.P., Schlott,B., Guhrs,K.H. and Bode,W.
    The ternary microplasmin-staphylokinase-microplasmin complex is a proteinase-cofactor-substrate complex in action
    Nat Struct Biol5, 917-923. PubMed  Europe PubMed DOI  S
  215. [YEAR:3-4-1998]Takeda-Shitaka,M. and Umeyama,H.
    Elucidation of the cause for reduced activity of abnormal human plasmin containing an Ala55-Thr mutation: Importance of highly conserved Ala55 in serine proteases
    FEBS Lett425, 448-452. PubMed  Europe PubMed DOI
  216. Wang,X., Lin,X., Loy,J.A., Tang,J. and Zhang,X.C.
    Crystal structure of the catalytic domain of human plasmin complexed with streptokinase
    Science281, 1662-1665. PubMed  Europe PubMed DOI  S
    217. 1997
  217. Butenas,S., DiLorenzo,M.E. and Mann,K.G.
    Ultrasensitive fluorogenic substrates for serine proteases
    Thromb Haemost78, 1193-1201. PubMed  Europe PubMed  A
  218. Okumura,Y., Sato,H., Seiki,M. and Kido,H.
    Proteolytic activation of the precursor of membrane type 1 matrix metalloproteinase by human plasmin. A possible cell surface activator
    FEBS Lett402, 181-184. PubMed  Europe PubMed DOI
  219. Pirie-Shepherd,S.R., Stevens,R.D., Andon,N.L., Enghild,J.J. and Pizzo,S.V.
    Evidence for a novel O-linked sialylated trisaccharide on Ser-248 of human plasminogen 2
    J Biol Chem272, 7408-7411. PubMed  Europe PubMed DOI
  220. Schlott,B., Guhrs,K.H., Hartmann,M., Rocker,A. and Collen,D.
    Staphylokinase requires NH2-terminal proteolysis for plasminogen activation
    J Biol Chem272, 6067-6072. PubMed  Europe PubMed DOI
  221. Wang,H., Prorok,M., Bretthauer,R.K. and Castellino,F.J.
    Serine-578 is a major phosphorylation locus in human plasma plasminogen
    Biochemistry36, 8100-8106. PubMed  Europe PubMed DOI
    222. 1996
  222. Lijnen,H.R., Van Hoef,B. and Collen,D.
    Characterization of the murine plasminogen/urokinase-type plasminogen-activator system
    Eur J Biochem241, 840-848. PubMed  Europe PubMed
  223. Romer,J., Bugge,T.H., Pyke,C., Lund,L.R., Flick,M.J., Degen,J.L. and Dano,K.
    Impaired wound healing in mice with a disrupted plasminogen gene
    Nat Med2, 287-292. PubMed  Europe PubMed  K
  224. Ueshima,S., Okada,K. and Matsuo,O.
    Stabilization of plasmin by lysine derivatives
    Clin Chim Acta245, 7-18. PubMed  Europe PubMed DOI  I
  225. Wijkmans,J.C.H.M., Nagel,A. and Bloemhoff,W.
    A novel chromogenic plasmin substrate Isoval-Phe-Lys-pNA-hydrochloride: a mild approach to the synthesis of N-alpha-peptidyl-L-lysine p-nitroanilides
    Int J Pept Res Ther3, 107-112.  A
    226. 1995
  226. Bugge,T.H., Flick,M.J., Daugherty,C.C. and Degen,J.L.
    Plasminogen deficiency causes severe thrombosis but is compatible with development and reproduction
    Genes Dev9, 794-807. PubMed  Europe PubMed  K
  227. Matsuzaki,T., Umeyama,H. and Kikumoto,R.
    Mechanisms of the selective inhibition of thrombin, factor Xa, plasmin and trypsin
    Pharmacochem Libr23, 83-95. DOI  S  I
  228. [YEAR:1-11-1995]Ploplis,V.A., Carmeliet,P., Vazirzadeh,S., Van Vlaenderen,I., Moons,L., Plow,E.F. and Collen,D.
    Effects of disruption of the plasminogen gene on thrombosis, growth, and health in mice
    Circulation92, 2585-2593. PubMed  Europe PubMed  K
  229. Plow,E.F., Herren,T., Redlitz,A., Miles,L.A. and Hoover-Plow,J.L.
    The cell biology of the plasminogen system
    FASEB J9, 939-945. PubMed  Europe PubMed
  230. Redlitz,A., Tan,A.K., Eaton,D.L. and Plow,E.F.
    Plasma carboxypeptidases as regulators of the plasminogen system
    J Clin Invest96, 2534-2538. PubMed  Europe PubMed DOI
  231. Wang,J. and Reich,E.
    Structure and function of microplasminogen: II. Determinants of activation by urokinase and by the bacterial activator streptokinase
    Protein Sci4, 1768-1779. PubMed  Europe PubMed DOI
    232. 1994
  232. Donovan,F.M., Vaughan,P.J. and Cunningham,D.D.
    Regulation of protease nexin-1 target protease specificity by collagen type IV
    J Biol Chem269, 17199-17205. PubMed  Europe PubMed
  233. Varadi,K., Philapitsch,A., Santa,T. and Schwarz,H.P.
    Activation and inactivation of human protein C by plasmin
    Thromb Haemost71, 615-621. PubMed  Europe PubMed
    234. 1993
  234. [YEAR:15-7-1993]Azuma,H., Uno,Y., Shigekiyo,T. and Saito,S.
    Congenital plasminogen deficiency caused by a Ser572 to Pro mutation
    Blood82, 475-480. PubMed  Europe PubMed  M
  235. [YEAR:15-4-1993]Collen,D., Schlott,B., Engelborghs,Y., Van Hoef,B., Hartmann,M., Lijnen,H.R. and Behnke,D.
    On the mechanism of the activation of human plasminogen by recombinant staphylokinase
    J Biol Chem268, 8284-8289. PubMed  Europe PubMed  I
  236. Teno,N., Wanaka,K., Okada,Y., Taguchi,H., Okamoto,U., Hijikata-Okunomiya,A. and Okamoto,S.
    Development of active center-directed plasmin and plasma kallikrein inhibitors and studies on the structure-inhibitory activity relationship
    Chem Pharm Bull (Tokyo)41, 1079-1090. PubMed  Europe PubMed  I
    237. 1992
  237. Ichinose,A.
    Multiple members of the plasminogen-apolipoprotein(a) gene family associated with thrombosis
    Biochemistry31, 3113-3118. PubMed  Europe PubMed DOI
  238. Ponting,C.P., Marshall,J.M. and Cederholm-Williams,S.A.
    Plasminogen: a structural review
    Blood Coagul Fibrinolysis3, 605-614. PubMed  Europe PubMed
    239. 1991
  239. Chain,D., Kreizman,T., Shapira,H. and Shaltiel,S.
    Plasmin cleavage of vitronectin. Identification of the site and consequent attenuation in binding plasminogen activator inhibitor-1
    FEBS Lett285, 251-256. PubMed  Europe PubMed DOI
    240. 1990
  240. Degen,S.J., Bell,S.M., Schaefer,L.A. and Elliott,R.W.
    Characterization of the cDNA coding for mouse plasminogen and localization of the gene to mouse chromosome 17
    Genomics8, 49-61. PubMed  Europe PubMed DOI
  241. [YEAR:15-4-1990]Petersen,T.E., Martzen,M.R., Ichinose,A. and Davie,E.W.
    Characterization of the gene for human plasminogen, a key proenzyme in the fibrinolytic system
    J Biol Chem265, 6104-6111. PubMed  Europe PubMed  M
    242. 1989
  242. Whitefleet-Smith,J., Rosen,E., McLinden,J., Ploplis,V.A., Fraser,M.J., Tomlinson,J.E., McLean,J.W. and Castellino,F.J.
    Expression of human plasminogen cDNA in a baculovirus vector-infected insect cell system
    Arch Biochem Biophys271, 390-399. PubMed  Europe PubMed  E
    243. 1988
  243. Castellino,F.J., Urano,T., de Serrano,V., Morris,J.P. and Chibber,B.A.
    Control of human plasminogen activation
    Haemostasis18 Suppl 1, 15-23. PubMed  Europe PubMed
  244. [YEAR:15-9-1988]Hortin,G.L., Gibson,B.L. and Fok,K.F.
    Alpha 2-antiplasmin's carboxy-terminal lysine residue is a major site of interaction with plasmin
    Biochem Biophys Res Commun155, 591-596. PubMed  Europe PubMed
  245. Saino,T., Someno,T., Ishii,S., Aoyagi,T. and Umezawa,H.
    Protease-inhibitory activities of leupeptin analogues
    J Antibiot (Tokyo)41, 220-225. PubMed  Europe PubMed  I
    246. 1987
  246. [YEAR:1-2-1987]Angliker,H., Wikstrom,P., Rauber,P. and Shaw,E.
    The synthesis of lysylfluoromethanes and their properties as inhibitors of trypsin, plasmin and cathepsin B
    Biochem J241, 871-875. PubMed  Europe PubMed  I
  247. Schaller,J., Marti,T., Rosselet,S.J., Kampfer,U. and Rickli,E.E.
    Amino acid sequence of the heavy chain of porcine plasmin. Comparison of the carbohydrate attachment sites with the human and bovine species
    Fibrinolysis1, 91-102.
    248. 1986
  248. [YEAR:25-1-1986]Collen,D., Zamarron,C., Lijnen,H.R. and Hoylaerts,M.
    Activation of plasminogen by pro-urokinase. II. Kinetics
    J Biol Chem261, 1259-1266. PubMed  Europe PubMed
  249. [YEAR:25-1-1986]Lijnen,H.R., Zamarron,C., Blaber,M., Winkler,M.E. and Collen,D.
    Activation of plasminogen by pro-urokinase. I. Mechanism
    J Biol Chem261, 1253-1258. PubMed  Europe PubMed
    250. 1984
  250. Castellino,F.J.
    Biochemistry of human plasminogen
    Semin Thromb Hemost10, 18-23. PubMed  Europe PubMed DOI
    251. 1982
  251. Friberger,P., Knos,M., Gustavsson,S., Aurell,L. and Claeson,G.
    12. A new specific substrate for the determination of plasmin activity
    Scand J Clin Lab Invest42, 121-127. DOI  A
  252. Ranby,M.
    Studies on the kinetics of plasminogen activation by tissue plasminogen activator
    Biochim Biophys Acta704, 461-469. PubMed  Europe PubMed
  253. Teger-Nilsson,A.-C., Friberger,P. and Gyzander,E.
    Determination of a new rapid plasmin inhibitor in human blood by means of a plasmin specific tripeptide substrate
    Scand J Clin Lab Invest42, 403-409. DOI  A
    254. 1981
  254. Castellino,F.J. and Powell,J.R.
    Human plasminogen
    Methods Enzymol80, 365-378. PubMed  Europe PubMed DOI  V
  255. Robbins,K.C., Summaria,L. and Wohl,R.C.
    Human plasmin
    Methods Enzymol80, 379-387. PubMed  Europe PubMed DOI  V
  256. [YEAR:1-9-1981]Suenson,E. and Thorsen,S.
    Secondary-site binding of Glu-plasmin, Lys-plasmin and miniplasmin to fibrin
    Biochem J197, 619-628. PubMed  Europe PubMed
  257. [YEAR:29-5-1981]Thorsen,S., Clemmensen,I., Sottrup-Jensen,L. and Magnusson,S.
    Adsorption to fibrin of native fragments of known primary structure from human plasminogen
    Biochim Biophys Acta668, 377-387. PubMed  Europe PubMed
    258. 1980
  258. Jackson,C.M. and Nemerson,Y.
    Blood coagulation
    Annu Rev Biochem49, 765-811. PubMed  Europe PubMed DOI
  259. Kato,H., Adachi,N., Ohno,Y., Iwanaga,S., Takada,K. and Sakakibara,S.
    New fluorogenic peptide substrates for plasmin
    J Biochem88, 183-190. PubMed  Europe PubMed  A
  260. [YEAR:10-11-1980]Lijnen,H.R., Hoylaerts,M. and Collen,D.
    Isolation and characterization of a human plasma protein with affinity for the lysine binding sites in plasminogen. Role in the regulation of fibrinolysis and identification as histidine-rich glycoprotein
    J Biol Chem255, 10214-10222. PubMed  Europe PubMed
    261. 1979
  261. Castellino,F.J.
    A unique enzyme-protein substrate modifier reaction: plasmin/streptokinase interaction
    Trends Biochem Sci4, 1-5.
  262. [YEAR:25-7-1979]Wiman,B., Lijnen,H.R. and Collen,D.
    On the specific interaction between the lysine-binding sites in plasmin and complementary sites in alpha2-antiplasmin and in fibrinogen
    Biochim Biophys Acta579, 142-154. PubMed  Europe PubMed
    263. 1978
  263. Goldsmith,G.H., Jr., Saito,H. and Ratnoff,O.S.
    The activation of plasminogen by Hageman factor (Factor XII) and Hageman factor fragments
    J Clin Invest62, 54-60. PubMed  Europe PubMed DOI
  264. [YEAR:10-3-1978]Sugino,H., Kakinuma,A. and Iwanaga,S.
    Plasminostreptin, a protein proteinase inhibitor produced by Streptomyces antifibrinolyticus. III. Elucidation of the primary structure
    J Biol Chem253, 1546-1555. PubMed  Europe PubMed
  265. [YEAR:1-6-1978]Wiman,B., Boman,L. and Collen,D.
    On the kinetics of the reaction between human antiplasmin and a low-molecular-weight form of plasmin
    Eur J Biochem87, 143-146. PubMed  Europe PubMed
  266. [YEAR:15-3-1978]Wiman,B. and Collen,D.
    On the kinetics of the reaction between human antiplasmin and plasmin
    Eur J Biochem84, 573-578. PubMed  Europe PubMed
    267. 1976
  267. Castellino,F.J. and Sodetz,J.M.
    Rabbit plasminogen and plasmin isozymes
    Methods Enzymol45, 273-286. PubMed  Europe PubMed DOI  V
  268. Robbins,K.C. and Summaria,L.
    Plasminogen and plasmin
    Methods Enzymol45, 257-273. PubMed  Europe PubMed DOI  V
    269. 1975
  269. Harpel,P.C. and Cooper,N.R.
    Studies on human plasma C1 inactivator-enzyme interactions. I. Mechanisms of interaction with C1s, plasmin, and trypsin
    J Clin Invest55, 593-604. PubMed  Europe PubMed DOI
  270. Robbins,K.C., Boreisha,I.G., Arzadon,L., Summaria,L. and Barlow,G.H.
    Physical and chemical properties of the NH2-terminal glutamic acid and lysine forms of human plasminogen and their derived plasmins with an NH2-terminal lysine heavy (A) chain. Comparative data
    J Biol Chem250, 4044-4047. PubMed  Europe PubMed
  271. Wiman,B.W. and Wallen,P.
    Structural relationship between "glutamic acid" and "lysine" forms of human plasminogen and their interaction with the NH2- teminal activation peptide as studies by affinity chromatography
    Eur J Biochem50, 489-494. PubMed  Europe PubMed
    272. 1973
  272. Coats,E.A.
    Comparative inhibition of thrombin, plasmin, trypsin, and complement by benzamidines using substituent constants and regression analysis
    J Med Chem16, 1102-1106. PubMed  Europe PubMed  I
    273. 1972
  273. Wallen,P. and Wiman,B.
    Characterization of human plasminogen. II. Separation and partial characterization of different molecular forms of human plasminogen
    Biochim Biophys Acta257, 122-134. PubMed  Europe PubMed
    274. 1970
  274. Wallen,P. and Wiman,B.
    Characterization of human plasminogen. I. On the relationship between different molecular forms of plasminogen demonstrated in plasma and found in purified preparations
    Biochim Biophys Acta221, 20-30. PubMed  Europe PubMed
    275. 1969
  275. Chase,T., Jr. and Shaw,E.
    Comparison of the esterase activities of trypsin, plasmin, and thrombin on guanidinobenzoate esters. Titration of the enzymes
    Biochemistry8, 2212-2224. PubMed  Europe PubMed DOI  I
  276. [YEAR:29-4-1969]Colman,R.W.
    Activation of plasminogen by human plasma kallikrein
    Biochem Biophys Res Commun35, 273-279. PubMed  Europe PubMed
  277. Ratnoff,O.D., Pensky,J., Ogston,D. and Naff,G.B.
    The inhibition of plasmin, plasma kallikrein, plasma permeability factor, and the C'1r subcomponent of the first component of complement by serum C'1 esterase inhibitor
    J Exp Med129, 315-331. PubMed  Europe PubMed
    278. 1967
  278. Robbins,K.C., Summaria,L., Hsieh,B. and Shah,R.J.
    The peptide chains of human plasmin. Mechanism of activation of human plasminogen to plasmin
    J Biol Chem242, 2333-2342. PubMed  Europe PubMed
  279. Summaria,L., Hsieh,B., Groskopf,W.R. and Robbins,K.C.
    The isolation and characterization of the S-carboxymethyl beta (light) chain derivative of human plasmin. The localization of the active site on the beta (light) chain
    J Biol Chem242, 5046-5052. PubMed  Europe PubMed
    280. 1965
  280. Hummel,B.C.W., Schor,J.M., Buck,F.F., Boggiano,E. and DeRenzo,E.C.
    Quantitative enzymic assay of human plasminogen and plasmin with azocasein as substrate
    Anal Biochem11, 532-547.  A
    281. 1958
  281. [YEAR:1-7-1958]Norman,P.S.
    Studies of the plasmin system. II. Inhibition of plasmin by serum or plasma
    J Exp Med108, 53-68. PubMed  Europe PubMed
  282. [YEAR:1-11-1958]Norman,P.S. and Hill,B.M.
    Studies of the plasmin system. III. Physical properties of the two plasmin inhibitors in plasma
    J Exp Med108, 639-649. PubMed  Europe PubMed
    283. 1955
  283. Grossi,C.E. and Cliffton,E.E.
    The lysis of arterial thrombi in rabbits and dogs by use of activated human plasminogen (fibrinolysin) (plasmin)
    Surgery37, 794-802. PubMed  Europe PubMed  U
    284. 1952
  284. Astrup,T. and Mullertz,S.
    The fibrin plate method for estimating fibrinolytic activity
    Arch Biochem Biophys40, 346-351. PubMed  Europe PubMed  A
  285. Kocholaty,W., Ellis,W.W. and Jensen,H.
    Activation of plasminogen by trypsin and plasmin
    Blood7, 882-890. PubMed  Europe PubMed
    286. 1947
  286. Astrup,T. and Permin,P.M.
    Fibrinolysis in the animal organism
    Nature159, 681-682. PubMed  Europe PubMed
    287. 1945
  287. Christensen,L.R. and Macleod,C.M.
    A proteolytic enzyme of serum: characterization, activation, and reaction with inhibitors
    J Gen Physiol28, 559-583. PubMed  Europe PubMed

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