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Literature for peptidase S01.152: chymotrypsin B

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: S Structure, P Specificity, E Expression, L Localization, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Demcsak,A., Hegyi,E., Hegyi,P., Rosendahl,J. and Sahin-Toth,M.<br>Chymotrypsin B2 (CTRB2) Deletion Variant Induces Endoplasmic Reticulum Stress but does not Increase Risk for Chronic Pancreatitis<br>Pancreas (2025) PubMed  Europe PubMed DOI
  2. Morales Granda,N.C., Szabo,A., Koller,Z., Pal,G. and Sahin-Toth,M.<br>Engineering mouse chymotrypsin B1 for improved trypsinogen degradation<br>Sci Rep (2025) 15, 10201-10201. PubMed  Europe PubMed DOI  PMC  EPMC
    3. 2024
  3. Moreau,T., Recoules,E., De Pauw,M., Labas,V. and Rehault-Godbert,S.<br>Evidence that the Bowman-Birk inhibitor from Pisum sativum affects intestinal proteolytic activities in chickens<br>Poult Sci (2024) 103, 103182-103182. PubMed  Europe PubMed DOI  PMC  EPMC  L
    4. 2021
  4. Jermusyk,A., Zhong,J., Connelly,K.E., Gordon,N., Perera,S., Abdolalizadeh,E., Zhang,T., O'Brien,A., Hoskins,J.W., Collins,I., Eiser,D., Yuan,C., Risch,H.A., Jacobs,E.J., Li,D., Du,M., Stolzenberg-Solomon,R.Z., Klein,A.P., Smith,J.P., Wolpin,B.M., Chanock,S.J., Shi,J., Petersen,G.M., Westlake,C.J. and Amundadottir,L.T.<br>A 584 bp deletion in CTRB2 inhibits chymotrypsin B2 activity and secretion and confers risk of pancreatic cancer<br>Am J Hum Genet (2021) 108, 1852-1865. PubMed  Europe PubMed DOI
    5. 2016
  5. Szabo,A., Pilsak,C., Bence,M., Witt,H. and Sahin-Toth,M.<br>Complex formation of human proelastases with procarboxypeptidases A1 and A2<br>J Biol Chem (2016) 291, 17706-17716. PubMed  Europe PubMed DOI
    6. 2012
  6. Graf,L., Szilagyi,L. and Venekei,I.<br>Chymotrypsin<br>[ISSN:978-0-12-407742-3] (2012) 3, 2626-2633. DOI
    7. 2010
  7. Zhao,K., Zhao,X., Tu,Y., Miao,Q., Cao,D., Duan,W., Sun,Y., Wang,J., Wei,T. and Yang,F.<br>Lysosomal chymotrypsin B potentiates apoptosis via cleavage of Bid<br>Cell Mol Life Sci (2010) 67, 2665-2678. PubMed  Europe PubMed DOI
    8. 2008
  8. Miao,Q., Sun,Y., Wei,T., Zhao,X., Zhao,K., Yan,L., Zhang,X., Shu,H. and Yang,F.<br>Chymotrypsin B cached in rat liver lysosomes and involved in apoptotic regulation through a mitochondrial pathway<br>J Biol Chem (2008) 283, 8218-8228. PubMed  Europe PubMed DOI
    9. 2007
  9. Psochiou,E., Sarropoulou,E., Mamuris,Z. and Moutou,K.A.<br>Sequence analysis and tissue expression pattern of Sparus aurata chymotrypsinogens and trypsinogen<br>Comp Biochem Physiol B Biochem Mol Biol (2007) 147, 367-377. PubMed  Europe PubMed DOI
    10. 2004
  10. Graf,L., Szilagyi,L. and Venekei,I.<br>Chymotrypsin<br>[ISSN:0-12-079610-4] (2004) 2, 1495-1501.  V
  11. Jelinek,B., Antal,J., Venekei,I. and Graf,L.<br>Ala226 to Gly and Ser189 to Asp mutations convert rat chymotrypsin B to a trypsin-like protease<br>Protein Eng Des Sel (2004) 17, 127-131. PubMed  Europe PubMed DOI
    12. 2003
  12. [YEAR:29-8-2003]Szabo,E., Venekei,I., Bocskei,Z., Naray-Szabo,G. and Graf,L.<br>Three dimensional structures of S189D chymotrypsin and D189S trypsin mutants: the effect of polarity at site 189 on a protease-specific stabilization of the substrate-binding site<br>J Mol Biol (29-8-2003) 331, 1121-1130. PubMed  Europe PubMed DOI  S
    13. 2001
  13. Curvers,S., Brixius,P., Klauser,T., Thommes,J., Weuster-Botz,D., Takors,R. and Wandrey,C.<br>Human chymotrypsinogen B production with Pichia pastoris by integrated development of fermentation and downstream processing. Part 1. Fermentation<br>Biotechnol Prog (2001) 17, 495-502. PubMed  Europe PubMed DOI
  14. Thommes,J., Halfar,M., Gieren,H., Curvers,S., Takors,R., Brunschier,R. and Kula,M.R.<br>Human chymotrypsinogen B production from Pichia pastoris by integrated development of fermentation and downstream processing. Part 2. Protein recovery<br>Biotechnol Prog (2001) 17, 503-512. PubMed  Europe PubMed DOI
    15. 2000
  15. [YEAR:5-7-2000]Harris,J.L., Backes,B.J., Leonetti,F., Mahrus,S., Ellman,J.A. and Craik,C.S.<br>Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries<br>Proc Natl Acad Sci U S A (5-7-2000) 97, 7754-7759. PubMed  Europe PubMed DOI  PMC  EPMC  P
    16. 1999
  16. [YEAR:6-8-1999]Guyonnet,V., Tluscik,F., Long,P.L., Polanowski,A. and Travis,J.<br>Purification and partial characterization of the pancreatic proteolytic enzymes trypsin, chymotrypsin, and elastase from the chicken<br>J Chromatogr A (6-8-1999) 852, 217-225. PubMed  Europe PubMed DOI
  17. Hudaky,P., Kaslik,G., Venekei,I. and Graf,L.<br>The differential specificity of chymotrypsin A and B is determined by amino acid 226<br>Eur J Biochem (1999) 259, 528-533. PubMed  Europe PubMed DOI
    18. 1998
  18. Wang,X.C., Strauss,K.I., Ha,Q.N., Nagula,S., Wolpoe,M.E. and Jacobowitz,D.M.<br>Chymotrypsin gene expression in rat peripheral organs<br>Cell Tissue Res (1998) 292, 345-354. PubMed  Europe PubMed DOI
    19. 1997
  19. Jiang,Q., Hall,M., Noriega,F.G. and Wells,M.<br>cDNA cloning and pattern of expression of an adult, female-specific chymotrypsin from Aedes aegypti midgut<br>Insect Biochem Mol Biol (1997) 27, 283-289. PubMed  Europe PubMed DOI
    20. 1996
  20. Venekei,I., Graf,L. and Rutter,W.J.<br>Expression of rat chymotrypsinogen in yeast: a study on the structural and functional significance of the chymotrypsinogen propeptide<br>FEBS Lett (1996) 379, 139-142. PubMed  Europe PubMed DOI  E
    21. 1995
  21. Raae,A.J., Flengsrud,R. and Sletten,K.<br>Chymotrypsin isoenzymes in Atlantic cod; differences in kinetics and substrate specificity<br>Comp Biochem Physiol B Biochem Mol Biol (1995) 112, 393-398. PubMed  Europe PubMed DOI
    22. 1989
  22. Tomita,N., Izumoto,Y., Horii,A., Doi,S., Yokouchi,H., Ogawa,M., Mori,T. and Matsubara,K.<br>Molecular cloning and nucleotide sequence of human pancreatic prechymotrypsinogen cDNA<br>Biochem Biophys Res Commun (1989) 158, 569-575. PubMed  Europe PubMed
    23. 1984
  23. Honey,N.K., Sakaguchi,A.Y., Lalley,P.A., Quinto,C., Macdonald,R.J., Craik,C., Bell,G.I., Rutter,W.J. and Naylor,S.L.<br>Chromosomal assignments of genes for trypsin, chymotrypsin B, and elastase in mouse<br>Somat Cell Mol Genet (1984) 10, 377-383. PubMed  Europe PubMed
    24. 1970
  24. Wilcox,P.E.<br>Chymotrypsinogens - chymotrypsins<br>Methods Enzymol (1970) 19, 64-108. DOI  V
    25. 1968
  25. Gratecos,D. and Desnuelle,P.<br>On porcine chymotrypsinogen B<br>FEBS Lett (1968) 1, 117-118. PubMed  Europe PubMed
    26. 1965
  26. Hartley,B.S., Brown,J.R., Kauffman,D.L. and Smillie,L.B.<br>Evolutionary similarities between pancreatic proteolytic enzymes<br>Nature (1965) 207, 1157-1159. PubMed  Europe PubMed DOI
    27. 1963
  27. Enenkel,A.G. and Smillie,L.B.<br>Specificity of chymotrypsin B toward glucagon<br>Biochemistry (1963) 2, 1449-1454. PubMed  Europe PubMed
  28. Enenkel,A.G. and Smillie,L.B.<br>Preparation and purity of chymotrypsinogen B<br>Biochemistry (1963) 2, 1445-1448. PubMed  Europe PubMed
    29. 1962
  29. Kassell,B. and Laskowski,M., Sr.<br>A comparison of the terminal amino acids of chymotrypsinogen B and alpha-chymotrypsinogen<br>J Biol Chem (1962) 237, 413-417. PubMed  Europe PubMed
    30. 1961
  30. Kassell,B. and Laskowski,M., Sr.<br>The amino acid composition of chymotrypsinogen B<br>J Biol Chem (1961) 236, 1996-2000. PubMed  Europe PubMed
    31. 1960
  31. Laskowski,M. and Kassell,B.<br>Chromatographic studies with chymotrypsinogen B and chymotrypsin B<br>Acta Biochim Pol (1960) 7, 253-260. PubMed  Europe PubMed

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