Literature for peptidase S01.152: chymotrypsin B

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: S Structure, P Specificity, E Expression, L Localization, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Morales Granda,N.C., Szabo,A., Koller,Z., Pal,G. and Sahin-Toth,M.
    Engineering mouse chymotrypsin B1 for improved trypsinogen degradation
    Sci Rep15, 10201-10201. PubMed  Europe PubMed DOI
  2. 2024
  3. Moreau,T., Recoules,E., De Pauw,M., Labas,V. and Rehault-Godbert,S.
    Evidence that the Bowman-Birk inhibitor from Pisum sativum affects intestinal proteolytic activities in chickens
    Poult Sci103, 103182-103182. PubMed  Europe PubMed DOI  L
  4. 2021
  5. Jermusyk,A., Zhong,J., Connelly,K.E., Gordon,N., Perera,S., Abdolalizadeh,E., Zhang,T., O'Brien,A., Hoskins,J.W., Collins,I., Eiser,D., Yuan,C., Risch,H.A., Jacobs,E.J., Li,D., Du,M., Stolzenberg-Solomon,R.Z., Klein,A.P., Smith,J.P., Wolpin,B.M., Chanock,S.J., Shi,J., Petersen,G.M., Westlake,C.J. and Amundadottir,L.T.
    A 584 bp deletion in CTRB2 inhibits chymotrypsin B2 activity and secretion and confers risk of pancreatic cancer
    Am J Hum Genet108, 1852-1865. PubMed  Europe PubMed DOI
  6. 2016
  7. Szabo,A., Pilsak,C., Bence,M., Witt,H. and Sahin-Toth,M.
    Complex formation of human proelastases with procarboxypeptidases A1 and A2
    J Biol Chem291, 17706-17716. PubMed  Europe PubMed DOI
  8. 2012
  9. Graf,L., Szilagyi,L. and Venekei,I.
    Chymotrypsin
    [ISSN:978-0-12-407742-3]3, 2626-2633. DOI
  10. 2010
  11. Zhao,K., Zhao,X., Tu,Y., Miao,Q., Cao,D., Duan,W., Sun,Y., Wang,J., Wei,T. and Yang,F.
    Lysosomal chymotrypsin B potentiates apoptosis via cleavage of Bid
    Cell Mol Life Sci67, 2665-2678. PubMed  Europe PubMed DOI
  12. 2008
  13. Miao,Q., Sun,Y., Wei,T., Zhao,X., Zhao,K., Yan,L., Zhang,X., Shu,H. and Yang,F.
    Chymotrypsin B cached in rat liver lysosomes and involved in apoptotic regulation through a mitochondrial pathway
    J Biol Chem283, 8218-8228. PubMed  Europe PubMed DOI
  14. 2007
  15. Psochiou,E., Sarropoulou,E., Mamuris,Z. and Moutou,K.A.
    Sequence analysis and tissue expression pattern of Sparus aurata chymotrypsinogens and trypsinogen
    Comp Biochem Physiol B Biochem Mol Biol147, 367-377. PubMed  Europe PubMed DOI
  16. 2004
  17. Graf,L., Szilagyi,L. and Venekei,I.
    Chymotrypsin
    [ISSN:0-12-079610-4]2, 1495-1501.  V
  18. Jelinek,B., Antal,J., Venekei,I. and Graf,L.
    Ala226 to Gly and Ser189 to Asp mutations convert rat chymotrypsin B to a trypsin-like protease
    Protein Eng Des Sel17, 127-131. PubMed  Europe PubMed DOI
  19. 2003
  20. [YEAR:29-8-2003]Szabo,E., Venekei,I., Bocskei,Z., Naray-Szabo,G. and Graf,L.
    Three dimensional structures of S189D chymotrypsin and D189S trypsin mutants: the effect of polarity at site 189 on a protease-specific stabilization of the substrate-binding site
    J Mol Biol331, 1121-1130. PubMed  Europe PubMed DOI  S
  21. 2001
  22. Curvers,S., Brixius,P., Klauser,T., Thommes,J., Weuster-Botz,D., Takors,R. and Wandrey,C.
    Human chymotrypsinogen B production with Pichia pastoris by integrated development of fermentation and downstream processing. Part 1. Fermentation
    Biotechnol Prog17, 495-502. PubMed  Europe PubMed DOI
  23. Thommes,J., Halfar,M., Gieren,H., Curvers,S., Takors,R., Brunschier,R. and Kula,M.R.
    Human chymotrypsinogen B production from Pichia pastoris by integrated development of fermentation and downstream processing. Part 2. Protein recovery
    Biotechnol Prog17, 503-512. PubMed  Europe PubMed DOI
  24. 2000
  25. [YEAR:5-7-2000]Harris,J.L., Backes,B.J., Leonetti,F., Mahrus,S., Ellman,J.A. and Craik,C.S.
    Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries
    Proc Natl Acad Sci U S A97, 7754-7759. PubMed  Europe PubMed DOI  P
  26. 1999
  27. [YEAR:6-8-1999]Guyonnet,V., Tluscik,F., Long,P.L., Polanowski,A. and Travis,J.
    Purification and partial characterization of the pancreatic proteolytic enzymes trypsin, chymotrypsin, and elastase from the chicken
    J Chromatogr A852, 217-225. PubMed  Europe PubMed DOI
  28. Hudaky,P., Kaslik,G., Venekei,I. and Graf,L.
    The differential specificity of chymotrypsin A and B is determined by amino acid 226
    Eur J Biochem259, 528-533. PubMed  Europe PubMed DOI
  29. 1998
  30. Wang,X.C., Strauss,K.I., Ha,Q.N., Nagula,S., Wolpoe,M.E. and Jacobowitz,D.M.
    Chymotrypsin gene expression in rat peripheral organs
    Cell Tissue Res292, 345-354. PubMed  Europe PubMed DOI
  31. 1997
  32. Jiang,Q., Hall,M., Noriega,F.G. and Wells,M.
    cDNA cloning and pattern of expression of an adult, female-specific chymotrypsin from Aedes aegypti midgut
    Insect Biochem Mol Biol27, 283-289. PubMed  Europe PubMed DOI
  33. 1996
  34. Venekei,I., Graf,L. and Rutter,W.J.
    Expression of rat chymotrypsinogen in yeast: a study on the structural and functional significance of the chymotrypsinogen propeptide
    FEBS Lett379, 139-142. PubMed  Europe PubMed DOI  E
  35. 1995
  36. Raae,A.J., Flengsrud,R. and Sletten,K.
    Chymotrypsin isoenzymes in Atlantic cod; differences in kinetics and substrate specificity
    Comp Biochem Physiol B Biochem Mol Biol112, 393-398. PubMed  Europe PubMed DOI
  37. 1989
  38. Tomita,N., Izumoto,Y., Horii,A., Doi,S., Yokouchi,H., Ogawa,M., Mori,T. and Matsubara,K.
    Molecular cloning and nucleotide sequence of human pancreatic prechymotrypsinogen cDNA
    Biochem Biophys Res Commun158, 569-575. PubMed  Europe PubMed
  39. 1984
  40. Honey,N.K., Sakaguchi,A.Y., Lalley,P.A., Quinto,C., Macdonald,R.J., Craik,C., Bell,G.I., Rutter,W.J. and Naylor,S.L.
    Chromosomal assignments of genes for trypsin, chymotrypsin B, and elastase in mouse
    Somat Cell Mol Genet10, 377-383. PubMed  Europe PubMed
  41. 1970
  42. Wilcox,P.E.
    Chymotrypsinogens - chymotrypsins
    Methods Enzymol19, 64-108. DOI  V
  43. 1968
  44. Gratecos,D. and Desnuelle,P.
    On porcine chymotrypsinogen B
    FEBS Lett1, 117-118. PubMed  Europe PubMed
  45. 1965
  46. Hartley,B.S., Brown,J.R., Kauffman,D.L. and Smillie,L.B.
    Evolutionary similarities between pancreatic proteolytic enzymes
    Nature207, 1157-1159. PubMed  Europe PubMed DOI
  47. 1963
  48. Enenkel,A.G. and Smillie,L.B.
    Preparation and purity of chymotrypsinogen B
    Biochemistry2, 1445-1448. PubMed  Europe PubMed
  49. Enenkel,A.G. and Smillie,L.B.
    Specificity of chymotrypsin B toward glucagon
    Biochemistry2, 1449-1454. PubMed  Europe PubMed
  50. 1962
  51. Kassell,B. and Laskowski,M., Sr.
    A comparison of the terminal amino acids of chymotrypsinogen B and alpha-chymotrypsinogen
    J Biol Chem237, 413-417. PubMed  Europe PubMed
  52. 1961
  53. Kassell,B. and Laskowski,M., Sr.
    The amino acid composition of chymotrypsinogen B
    J Biol Chem236, 1996-2000. PubMed  Europe PubMed
  54. 1960
  55. Laskowski,M. and Kassell,B.
    Chromatographic studies with chymotrypsinogen B and chymotrypsin B
    Acta Biochim Pol7, 253-260. PubMed  Europe PubMed