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Literature for peptidase S01.149: mast cell peptidase 4 (mouse numbering)

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

(Topics flags: P Specificity, I Inhibitor, K Knockout, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2020
  1. Berglund,P., Akula,S., Fu,Z., Thorpe,M. and Hellman,L.<br>Extended Cleavage Specificity of the Rat Vascular Chymase, a Potential Blood Pressure Regulating Enzyme Expressed by Rat Vascular Smooth Muscle Cells<br>Int J Mol Sci (2020) 21 PubMed  Europe PubMed DOI  PMC  EPMC
  2. Cespedes,N., Donnelly,E., Garrison,S., Haapanen,L., Van De Water,J. and Luckhart,S.<br>Non-lethal Plasmodium yoelii infection drives complex patterns of Th2-type host immunity and mast cell-dependent bacteremia<br>Infect Immun (2020) PubMed  Europe PubMed DOI
  3. Magnusdottir,E.I., Grujic,M., Bergman,J., Pejler,G. and Lagerstrom,M.C.<br>Mouse connective tissue mast cell proteases tryptase and carboxypeptidase A3 play protective roles in itch induced by endothelin-1<br>J Neuroinflammation (2020) 17, 123-123. PubMed  Europe PubMed DOI  PMC  EPMC
    4. 2019
  4. Vangansewinkel,T., Lemmens,S., Geurts,N., Quanten,K., Dooley,D., Pejler,G. and Hendrix,S.<br>Mouse mast cell protease 4 suppresses scar formation after traumatic spinal cord injury<br>Sci Rep (2019) 9, 3715-3715. PubMed  Europe PubMed DOI  PMC  EPMC  K
    5. 2018
  5. Houde,M., Schwertani,A., Touil,H., Desbiens,L., Sarrhini,O., Lecomte,R., Lepage,M., Gagnon,H., Takai,S., Pejler,G., Jacques,D., Gobeil F Jr, Day,R. and D'Orleans-Juste,P.<br>Mouse mast cell protease 4 deletion protects heart function and survival after permanent myocardial infarction<br>Front Pharmacol (2018) 9, 868-868. PubMed  Europe PubMed DOI  PMC  EPMC  K
    6. 2017
  6. Shubin,N.J., Glukhova,V.A., Clauson,M., Truong,P., Abrink,M., Pejler,G., White,N.J., Deutsch,G.H., Reeves,S.R., Vaisar,T., James,R.G. and Piliponsky,A.M.<br>Proteome analysis of mast cell releasates reveals a role for chymase in the regulation of coagulation factor XIIIA levels via proteolytic degradation<br>J Allergy Clin Immunol (2017) 139, 323-334. PubMed  Europe PubMed DOI
    7. 2016
  7. Desbiens,L., Lapointe,C., Gharagozloo,M., Mahmoud,S., Pejler,G., Gris,D. and D'Orleans-Juste,P.<br>Significant contribution of mouse mast cell protease 4 in early phases of experimental autoimmune encephalomyelitis<br>Mediators Inflamm (2016) 2016, 9797021-9797021. PubMed  Europe PubMed DOI  PMC  EPMC
  8. Houde,M., Desbiens,L., Schwertani,A., Pejler,G., Iglarz,M. and D'Orleans-Juste,P.<br>Endothelin receptor antagonist macitentan or deletion of mouse mast cell protease 4 delays lesion development in atherosclerotic mice<br>Life Sci (2016) 159, 71-75. PubMed  Europe PubMed DOI  K
  9. Lind,T., Gustafson,A.M., Calounova,G., Hu,L., Rasmusson,A., Jonsson,K.B., Wernersson,S., Abrink,M., Andersson,G., Larsson,S., Melhus,H. and Pejler,G.<br>Increased bone mass in female mice lacking mast cell chymase<br>PLoS ONE (2016) 11, e0167964-e0167964. PubMed  Europe PubMed DOI  K
  10. Tejada,T., Tan,L., Torres,R.A., Calvert,J.W., Lambert,J.P., Zaidi,M., Husain,M., Berce,M.D., Naib,H., Pejler,G., Abrink,M., Graham,R.M., Lefer,D.J., Naqvi,N. and Husain,A.<br>IGF-1 degradation by mouse mast cell protease 4 promotes cell death and adverse cardiac remodeling days after a myocardial infarction<br>Proc Natl Acad Sci U S A (2016) 113, 6949-6954. PubMed  Europe PubMed DOI
    11. 2015
  11. Semaan,W., Desbiens,L., Houde,M., Labonte,J., Gagnon,H., Yamamoto,D., Takai,S., Laidlaw,T., Bkaily,G., Schwertani,A., Pejler,G., Levesque,C., Desjardins,R., Day,R. and D'Orleans-Juste,P.<br>Chymase inhibitor-sensitive synthesis of endothelin-1 (1-31) by recombinant mouse mast cell protease 4 and human chymase<br>Biochem Pharmacol (2015) 94, 91-100. PubMed  Europe PubMed DOI  I
    12. 2014
  12. Bankova,L.G., Lezcano,C., Pejler,G., Stevens,R.L., Murphy,G.F., Austen,K.F. and Gurish,M.F.<br>Mouse mast cell proteases 4 and 5 mediate epidermal injury through disruption of tight junctions<br>J Immunol (2014) 192, 2812-2820. PubMed  Europe PubMed DOI
  13. Nelissen,S., Vangansewinkel,T., Geurts,N., Geboes,L., Lemmens,E., Vidal,P.M., Lemmens,S., Willems,L., Boato,F., Dooley,D., Pehl,D., Pejler,G., Maurer,M., Metz,M. and Hendrix,S.<br>Mast cells protect from post-traumatic spinal cord damage in mice by degrading inflammation-associated cytokines via mouse mast cell protease 4<br>Neurobiol Dis (2014) 62, 260-272. PubMed  Europe PubMed DOI
    14. 2013
  14. Beghdadi,W., Madjene,L.C., Claver,J., Pejler,G., Beaudoin,L., Lehuen,A., Daugas,E. and Blank,U.<br>Mast cell chymase protects against renal fibrosis in murine unilateral ureteral obstruction<br>Kidney Int (2013) 84, 317-326. PubMed  Europe PubMed DOI  K
  15. Hendrix,S., Kramer,P., Pehl,D., Warnke,K., Boato,F., Nelissen,S., Lemmens,E., Pejler,G., Metz,M., Siebenhaar,F. and Maurer,M.<br>Mast cells protect from post-traumatic brain inflammation by the mast cell-specific chymase mouse mast cell protease-4<br>FASEB J (2013) 27, 920-929. PubMed  Europe PubMed DOI  K
  16. Waern,I., Lundequist,A., Pejler,G. and Wernersson,S.<br>Mast cell chymase modulates IL-33 levels and controls allergic sensitization in dust-mite induced airway inflammation<br>Mucosal Immunol (2013) 6, 911-920. PubMed  Europe PubMed DOI  K
    17. 2012
  17. Caughey,G.H.<br>Chymases<br>[ISSN:978-0-12-407742-3] (2012) 3, 2675-2683. DOI
  18. Piliponsky,A.M., Chen,C.C., Rios,E.J., Treuting,P.M., Lahiri,A., Abrink,M., Pejler,G., Tsai,M. and Galli,S.J.<br>The chymase mouse mast cell protease 4 degrades TNF, limits inflammation, and promotes survival in a model of sepsis<br>Am J Pathol (2012) 181, 875-886. PubMed  Europe PubMed DOI
    19. 2011
  19. Lin,L., Bankaitis,E., Heimbach,L., Li,N., Abrink,M., Pejler,G., An,L., Diaz,L.A., Werb,Z. and Liu,Z.<br>Dual targets for mouse mast cell protease-4 in mediating tissue damage in experimental bullous pemphigoid<br>J Biol Chem (2011) 286, 37358-37367. PubMed  Europe PubMed DOI  K
    20. 2010
  20. Kervinen,J., Crysler,C., Bayoumy,S., Abad,M.C., Spurlino,J., Deckman,I., Greco,M.N., Maryanoff,B.E. and de Garavilla,L.<br>Potency variation of small-molecule chymase inhibitors across species<br>Biochem Pharmacol (2010) 80, 1033-1041. PubMed  Europe PubMed DOI  I
  21. Trivedi,N.N. and Caughey,G.H.<br>Mast cell peptidases: chameleons of innate immunity and host defense<br>Am J Respir Cell Mol Biol (2010) 42, 257-267. PubMed  Europe PubMed DOI
  22. Younan,G., Suber,F., Xing,W., Shi,T., Kunori,Y., Abrink,M., Pejler,G., Schlenner,S.M., Rodewald,H.R., Moore,F.D., Jr., Stevens,R.L., Adachi,R., Austen,K.F. and Gurish,M.F.<br>The inflammatory response after an epidermal burn depends on the activities of mouse mast cell proteases 4 and 5<br>J Immunol (2010) 185, 7681-7690. PubMed  Europe PubMed DOI
    23. 2009
  23. Waern,I., Jonasson,S., Hjoberg,J., Bucht,A., Abrink,M., Pejler,G. and Wernersson,S.<br>Mouse mast cell protease 4 is the major chymase in murine airways and has a protective role in allergic airway inflammation<br>J Immunol (2009) 183, 6369-6376. PubMed  Europe PubMed DOI  K
    24. 2008
  24. Andersson,M.K., Karlson,U. and Hellman,L.<br>The extended cleavage specificity of the rodent beta-chymases rMCP-1 and mMCP-4 reveal major functional similarities to the human mast cell chymase<br>Mol Immunol (2008) 45, 766-775. PubMed  Europe PubMed DOI  P
    25. 2004
  25. Caughey,G.H.<br>Chymases<br>[ISSN:0-12-079610-4] (2004) 2, 1531-1535.  V
  26. Li,M., Liu,K., Michalicek,J., Angus,J.A., Hunt,J.E., Dell'Italia,L.J., Feneley,M.P., Graham,R.M. and Husain,A.<br>Involvement of chymase-mediated angiotensin II generation in blood pressure regulation<br>J Clin Invest (2004) 114, 112-120. PubMed  Europe PubMed DOI  PMC  EPMC
  27. [YEAR:1-6-2004]Lundequist,A., Tchougounova,E., Abrink,M. and Pejler,G.<br>Cooperation between mast cell carboxypeptidase A and the chymase mouse mast cell protease 4 in the formation and degradation of angiotensin II<br>J Biol Chem (1-6-2004) 279, 32339-32344. PubMed  Europe PubMed DOI
  28. Soga,Y., Takai,S., Koyama,T., Okamoto,Y., Ikeda,T., Nishimura,K., Miyazaki,M. and Komeda,M.<br>Attenuation of adhesion formation after cardiac surgery with a chymase inhibitor in a hamster model<br>J Thorac Cardiovasc Surg (2004) 127, 72-78. PubMed  Europe PubMed DOI  I
    29. 2003
  29. [YEAR:4-8-2003]Tchougounova,E., Pejler,G. and Abrink,M.<br>The chymase, mouse mast cell protease 4, constitutes the major chymotrypsin-like activity in peritoneum and ear tissue. A role for mouse mast cell protease 4 in thrombin regulation and fibronectin turnover<br>J Exp Med (4-8-2003) 198, 423-431. PubMed  Europe PubMed DOI  PMC  EPMC
    30. 2002
  30. [YEAR:1-9-2002]Hori,S., Yamada,M., Ohtani,S., Hori,C., Yokomizo,T., Webb,T. and Shimokawa,T.<br>Myonase is localized in skeletal muscle myofibrils<br>J Biochem (1-9-2002) 132, 417-425. PubMed  Europe PubMed
    31. 2001
  31. Kakizoe,E., Shiota,N., Tanabe,Y., Shimoura,K., Kobayashi,Y. and Okunishi,H.<br>Isoform-selective upregulation of mast cell chymase in the development of skin fibrosis in scleroderma model mice<br>J Invest Dermatol (2001) 116, 118-123. PubMed  Europe PubMed DOI
    32. 2000
  32. [YEAR:14-7-2000]Caughey,G.H., Raymond,W.W. and Wolters,P.J.<br>Angiotensin II generation by mast cell alpha- and beta-chymases<br>Biochim Biophys Acta (14-7-2000) 1480, 245-257. PubMed  Europe PubMed DOI
    33. 1999
  33. [YEAR:19-8-1999]Humphries,D.E., Wong,G.W., Friend,D.S., Gurish,M.F., Qiu,W.T., Huang,C., Sharpe,A.H. and Stevens,R.L.<br>Heparin is essential for the storage of specific granule proteases in mast cells<br>Nature (19-8-1999) 400, 769-772. PubMed  Europe PubMed DOI
  34. [YEAR:15-3-1999]Jippo,T., Lee,Y.M., Katsu,Y., Tsujino,K., Morii,E., Kim,D.K., Kim,H.M. and Kitamura,Y.<br>Deficient transcription of mouse mast cell protease 4 gene in mutant mice of mi/mi genotype<br>Blood (15-3-1999) 93, 1942-1950. PubMed  Europe PubMed
    35. 1998
  35. Holt,J.C., Hatcher,V.B., Caulfield,J.B., Norton,P., Umeda,P.K., Melendez,J.A., Martino,L., Mudzinsky,S.P., Blumenstock,F., Slayter,H.S. and Margossian,S.S.<br>Cloning of the cDNA and nucleotide sequence of a skeletal muscle protease from myopathic hamsters<br>Mol Cell Biochem (1998) 181, 125-135. PubMed  Europe PubMed DOI
  36. Hori,S., Ohtani,S., Hori,C. and Nokihara,K.<br>Purification and characterization of myonase from X-chromosome linked muscular dystrophic mouse skeletal muscle<br>J Biochem (1998) 123, 650-658. PubMed  Europe PubMed
  37. [YEAR:15-7-1998]Shiota,N., Fukamizu,A., Okunishi,H., Takai,S., Murakami,K. and Miyazaki,M.<br>Cloning of the gene and cDNA for hamster chymase 2, and expression of chymase 1, chymase 2 and angiotensin-converting enzyme in the terminal stage of cardiomyopathic hearts<br>Biochem J (15-7-1998) 333, 417-424. PubMed  Europe PubMed  PMC  EPMC
    38. 1997
  38. Lutzelschwab,C., Pejler,G., Aveskogh,M. and Hellman,L.<br>Secretory granule proteases in rat mast cells. Cloning of 10 different serine proteases and a carboxypeptidase A from various rat mast cell populations<br>J Exp Med (1997) 185, 13-29. PubMed  Europe PubMed DOI  PMC  EPMC
    39. 1996
  39. Itoh,H., Murakumo,Y., Tomita,M., Ide,H., Kobayashi,T., Maruyama,H., Horii,Y. and Nawa,Y.<br>Cloning of the cDNAs for mast-cell chymases from the jejunum of Mongolian gerbils, Meriones unguiculatus, and their sequence similarities with chymases expressed in the connective-tissue mast cells of mice and rats<br>Biochem J (1996) 314, 923-929. PubMed  Europe PubMed  PMC  EPMC
    40. 1995
  40. Pejler,G., Karlstrom,A.R. and Berg,L.<br>Identification of the proteolytic thrombin fragments formed after cleavage with rat mast cell protease 1<br>Eur J Biochem (1995) 227, 102-107. PubMed  Europe PubMed DOI
  41. Pejler,G. and Berg,L.<br>Regulation of rat mast cell protease 1 activity. Protease inhibition is prevented by heparin proteoglycan<br>Eur J Biochem (1995) 233, 192-199. PubMed  Europe PubMed
  42. Springman,E.B. and Serafin,W.E.<br>Structure, genetics, and regulation of expression of secretory endo- and exopeptidases of mouse mast cells<br>Clin Allergy Immunol (1995) 6, 169-201.
    43. 1994
  43. Huang,R. and Hellman,L.<br>Genes for mast-cell serine protease and their molecular evolution<br>Immunogenetics (1994) 40, 397-414. PubMed  Europe PubMed
  44. Rouleau,A., Garbarg,M., Schwartz,J.C. and Ruat,M.<br>Molecular cloning of rat mast cell protease 1 and development of specific probes for its gene transcript<br>Biochem Biophys Res Commun (1994) 199, 593-602. PubMed  Europe PubMed DOI
    45. 1993
  45. Gurish,M.F., Nadeau,J.H., Johnson,K.R., McNeil,H.P., Grattan,K.M., Austen,K.F. and Stevens,R.L.<br>A closely linked complex of mouse mast cell-specific chymase genes on chromosome 14<br>J Biol Chem (1993) 268, 11372-11379. PubMed  Europe PubMed
  46. [YEAR:25-4-1993]Sali,A., Matsumoto,R., McNeil,H.P., Karplus,M. and Stevens,R.L.<br>Three-dimensional models of four mouse mast cell chymases. Identification of proteoglycan binding regions and protease-specific antigenic epitopes<br>J Biol Chem (25-4-1993) 268, 9023-9034. PubMed  Europe PubMed
    47. 1991
  47. Huang,R.Y., Blom,T. and Hellman,L.<br>Cloning and structural analysis of MMCP-1, MMCP-4 and MMCP-5, three mouse mast cell-specific serine proteases<br>Eur J Immunol (1991) 21, 1611-1621. PubMed  Europe PubMed DOI
  48. [YEAR:25-1-1991]Serafin,W.E., Sullivan,T.P., Conder,G.A., Ebrahimi,A., Marcham,P., Johnson,S.S., Austen,K.F. and Reynolds,D.S.<br>Cloning of the cDNA and gene for mouse mast cell protease 4. Demonstration of its late transcription in mast cell subclasses and analysis of its homology to subclass-specific neutral proteases of the mouse and rat<br>J Biol Chem (25-1-1991) 266, 1934-1941. PubMed  Europe PubMed
    49. 1990
  49. Reynolds,D.S., Stevens,R.L., Lane,W.S., Carr,M.H., Austen,K.F. and Serafin,W.E.<br>Different mouse mast cell populations express various combinations of at least six distinct mast cell serine proteases<br>Proc Natl Acad Sci U S A (1990) 87, 3230-3234. PubMed  Europe PubMed  PMC  EPMC
    50. 1987
  50. Le Trong,H., Parmelee,D.C., Walsh,K.A., Neurath,H. and Woodbury,R.G.<br>Amino acid sequence of rat mast cell protease I (chymase)<br>Biochemistry (1987) 26, 6988-6994. PubMed  Europe PubMed
  51. Le Trong,H., Neurath,H. and Woodbury,R.G.<br>Substrate specificity of the chymotrypsin-like protease in secretory granules isolated from rat mast cells<br>Proc Natl Acad Sci U S A (1987) 84, 364-367. PubMed  Europe PubMed  PMC  EPMC
  52. Woodbury,R.G., Trong,H.L. and Neurath,H.<br>Structure and function of mast cell proteases<br>Acta Histochem Cytochem (1987) 20, 261-269.
    53. 1984
  53. Harper,J.W., Cook,R.R., Roberts,C.J., McLaughlin,B.J. and Powers,J.C.<br>Active site mapping of the serine proteases human leukocyte elastase, cathepsin G, porcine pancreatic elastase, rat mast cell proteases I and II, bovine chymotrypsin Aalpha, and Staphylococcus aureus protease V-8 using tripeptide thiobenzyl ester substrates<br>Biochemistry (1984) 23, 2995-3002. PubMed  Europe PubMed
    54. 1981
  54. Woodbury,R.G., Everitt,M.T. and Neurath,H.<br>Mast cell proteases<br>Methods Enzymol (1981) 80, 588-609. PubMed  Europe PubMed DOI  V
    55. 1980
  55. [YEAR:2-6-1980]Woodbury,R.G. and Neurath,H.<br>Structure, specificity and localization of the serine proteases of connective tissue<br>FEBS Lett (2-6-1980) 114, 189-196. PubMed  Europe PubMed DOI
  56. Yoshida,N., Everitt,M.T., Neurath,H., Woodbury,R.G. and Powers,J.C.<br>Substrate specificity of two chymotrypsin-like proteases from rat mast cells. Studies with peptide 4-nitroanilides and comparison with cathepsin G<br>Biochemistry (1980) 19, 5799-5804. PubMed  Europe PubMed  I
    57. 1978
  57. Woodbury,R.G., Everitt,M., Sanada,Y., Katunuma,N., Lagunoff,D. and Neurath,H.<br>A major serine protease in rat skeletal muscle: evidence for its mast cell origin<br>Proc Natl Acad Sci U S A (1978) 75, 5311-5313. PubMed  Europe PubMed  PMC  EPMC
  58. Woodbury,R.G., Gruzenski,G.M. and Lagunoff,D.<br>Immunofluorescent localization of a serine protease in rat small intestine<br>Proc Natl Acad Sci U S A (1978) 75, 2785-2789. PubMed  Europe PubMed  PMC  EPMC
    59. 1971
  59. Vensel,W.H., Komender,J. and Barnard,E.A.<br>Non-pancreatic proteases of the chymotrypsin family. II. Two proteases from a mouse mast cell tumor<br>Biochim Biophys Acta (1971) 250, 395-407. PubMed  Europe PubMed

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