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Literature for peptidase S01.136: granzyme B, rodent-type

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, A Assay, P Specificity, K Knockout, E Expression, V Review, M Mutation, I Inhibitor, L Localization. To select only the references relevant to a single topic, click the link above. See explanation.)

    2024
  1. Ben-Eltriki,M., Ahmadi,A.R., Nakao,Y., Golla,K., Lakschevitz,F., Hakkinen,L., Granville,D.J. and Kim,H.<br>Granzyme B promotes matrix metalloproteinase-1 (MMP-1) release from gingival fibroblasts in a PAR1- and Erk1/2-dependent manner: A novel role in periodontal inflammation<br>J Periodontal Res (2024) 59, 94-103. PubMed  Europe PubMed DOI
  2. Fu,J., Xi,H., Cai,S., Peng,Y., Liu,Q., Qiu,L. and Lin,J.<br>Development of Granzyme B-targeted Smart Positron Emission Tomography Probes for Monitoring Tumor Early Response to Immunotherapy<br>ACS Nano (2024) 18, 18910-18921. PubMed  Europe PubMed DOI
  3. Heidari,P., Haj-Mirzaian,A., Prabhu,S., Ataeinia,B., Esfahani,S.A. and Mahmood,U.<br>Granzyme B PET Imaging for Assessment of Disease Activity in Inflammatory Bowel Disease<br>J Nucl Med (2024) 65, 1137-1143. PubMed  Europe PubMed DOI
    4. 2022
  4. Xu,L., Liu,N., Zhan,W., Deng,Y., Chen,Z., Liu,X., Gao,G., Chen,Q., Liu,Z. and Liang,G.<br>Granzyme B Turns Nanoparticle Fluorescence "On" for Imaging Cytotoxic T Lymphocyte Activity in Vivo<br>ACS Nano (2022) 16, 19328-19334. PubMed  Europe PubMed DOI
    5. 2020
  5. Chitirala,P., Chang,H.F., Martzloff,P., Harenberg,C., Ravichandran,K., Abdulreda,M.H., Berggren,P.O., Krause,E., Schirra,C., Leinders-Zufall,T., Benseler,F., Brose,N. and Rettig,J.<br>Studying the biology of cytotoxic T lymphocytes in vivo with a fluorescent granzyme B-mTFP knock-in mouse<br>elife (2020) 9 PubMed  Europe PubMed DOI  PMC  EPMC
  6. Fu,Z., Akula,S., Thorpe,M. and Hellman,L.<br>Extended cleavage specificities of two mast cell chymase-related proteases and one granzyme B-like protease from the platypus, a monotreme<br>Int J Mol Sci (2020) 21 PubMed  Europe PubMed DOI
    7. 2018
  7. Shen,Y., Zeglinski,M.R., Turner,C.T., Raithatha,S.A., Wu,Z., Russo,V., Oram,C., Hiroyasu,S., Nabai,L., Zhao,H., Bozin,T., Westendorf,K., Kopko,I., Huang,R., Arns,S., Tan,J., Zeng,H., Boey,A., Liggins,R., Jaquith,J., Cameron,D.R., Papp,A. and Granville,D.J.<br>Topical small molecule granzyme B inhibitor improves remodeling in a murine model of impaired burn wound healing<br>Exp Mol Med (2018) 50, 68-68. PubMed  Europe PubMed DOI  PMC  EPMC  I
    8. 2017
  8. Larimer,B.M., Wehrenberg-Klee,E., Dubois,F., Mehta,A., Kalomeris,T., Flaherty,K., Boland,G. and Mahmood,U.<br>Granzyme B PET imaging as a predictive biomarker of immunotherapy response<br>Cancer Res (2017) 77, 2318-2327. PubMed  Europe PubMed DOI  L
    9. 2016
  9. Shen,Y., Cheng,F., Sharma,M., Merkulova,Y., Raithatha,S.A., Parkinson,L.G., Zhao,H., Westendorf,K., Bohunek,L., Bozin,T., Hsu,I., Ang,L.S., Williams,S.J., Bleackley,R.C., Eriksson,J.E., Seidman,M.A., McManus,B.M. and Granville,D.J.<br>Granzyme B deficiency protects against angiotensin II-induced cardiac fibrosis<br>Am J Pathol (2016) 186, 87-100. PubMed  Europe PubMed DOI  K
    10. 2015
  10. Parkinson,L.G., Toro,A., Zhao,H., Brown,K., Tebbutt,S.J. and Granville,D.J.<br>Granzyme B mediates both direct and indirect cleavage of extracellular matrix in skin after chronic low-dose ultraviolet light irradiation<br>Aging Cell (2015) 14, 67-77. PubMed  Europe PubMed DOI
    11. 2014
  11. Andoniou,C.E., Sutton,V.R., Wikstrom,M.E., Fleming,P., Thia,K.Y., Matthews,A.Y., Kaiserman,D., Schuster,I.S., Coudert,J.D., Eldi,P., Chaudhri,G., Karupiah,G., Bird,P.I., Trapani,J.A. and Degli-Esposti,M.A.<br>A natural genetic variant of granzyme B confers lethality to a common viral infection<br>PLoS Pathog (2014) 10, e1004526-e1004526. PubMed  Europe PubMed DOI  PMC  EPMC  M
  12. Hagn,M., Sutton,V.R. and Trapani,J.A.<br>A colorimetric assay that specifically measures granzyme B proteolytic activity: hydrolysis of Boc-Ala-Ala-Asp-S-Bzl<br>J Vis Exp (2014) , e52419-e52419. PubMed  Europe PubMed DOI  A  P
  13. Plasman,K., Maurer-Stroh,S., Gevaert,K. and Van Damme,P.<br>Holistic view on the extended substrate specificities of orthologous granzymes<br>J Proteome Res (2014) 13, 1785-1793. PubMed  Europe PubMed DOI  P
  14. Prakash,M.D., Munoz,M.A., Jain,R., Tong,P.L., Koskinen,A., Regner,M., Kleifeld,O., Ho,B., Olson,M., Turner,S.J., Mrass,P., Weninger,W. and Bird,P.I.<br>Granzyme B promotes cytotoxic lymphocyte transmigration via basement membrane remodeling<br>Immunity (2014) 41, 960-972. PubMed  Europe PubMed DOI
  15. Van Damme,P., Plasman,K., Vandemoortele,G., Jonckheere,V., Maurer-Stroh,S. and Gevaert,K.<br>Importance of extended protease substrate recognition motifs in steering BNIP-2 cleavage by human and mouse granzymes B<br>BMC Biochem (2014) 15, 21-21. PubMed  Europe PubMed DOI  P
    16. 2012
  16. Froelich,C.J.<br>Granzyme B<br>[ISSN:978-0-12-407742-3] (2012) 3, 2718-2721. DOI
  17. Hagn,M., Belz,G.T., Kallies,A., Sutton,V.R., Thia,K.Y., Tarlinton,D.M., Hawkins,E.D. and Trapani,J.A.<br>Activated mouse B cells lack expression of granzyme B<br>J Immunol (2012) 188, 3886-3892. PubMed  Europe PubMed DOI
  18. Stewart,S.E., Mangan,M.S., Bird,P.I. and Kaiserman,D.<br>Detection of human and mouse granzyme B activity in cell extracts<br>Methods Mol Biol (2012) 844, 251-260. PubMed  Europe PubMed DOI  A
    19. 2011
  19. Ang,L.S., Boivin,W.A., Williams,S.J., Zhao,H., Abraham,T., Carmine-Simmen,K., McManus,B.M., Bleackley,R.C. and Granville,D.J.<br>Serpina3n attenuates granzyme B-mediated decorin cleavage and rupture in a murine model of aortic aneurysm<br>Cell Death Dis (2011) 2, e209-e209. PubMed  Europe PubMed DOI
  20. Hiebert,P.R., Boivin,W.A., Abraham,T., Pazooki,S., Zhao,H. and Granville,D.J.<br>Granzyme B contributes to extracellular matrix remodeling and skin aging in apolipoprotein E knockout mice<br>Exp Gerontol (2011) 46, 489-499. PubMed  Europe PubMed DOI
    21. 2010
  21. Afonina,I.S., Cullen,S.P. and Martin,S.J.<br>Cytotoxic and non-cytotoxic roles of the CTL/NK protease granzyme B<br>Immunol Rev (2010) 235, 105-116. PubMed  Europe PubMed DOI  V
  22. D'Angelo,M.E., Bird,P.I., Peters,C., Reinheckel,T., Trapani,J.A. and Sutton,V.R.<br>Cathepsin H is an additional convertase of pro-granzyme B<br>J Biol Chem (2010) 285, 20514-20519. PubMed  Europe PubMed DOI
    23. 2009
  23. Boivin,W.A., Cooper,D.M., Hiebert,P.R. and Granville,D.J.<br>Intracellular versus extracellular granzyme B in immunity and disease: challenging the dogma<br>Lab Invest (2009) 89, 1195-1220. PubMed  Europe PubMed DOI  V
  24. Van Damme,P., Maurer-Stroh,S., Plasman,K., Van Durme,J., Colaert,N., Timmerman,E., De Bock,P.J., Goethals,M., Rousseau,F., Schymkowitz,J., Vandekerckhove,J. and Gevaert,K.<br>Analysis of protein processing by N-terminal proteomics reveals novel species-specific substrate determinants of granzyme B orthologs<br>Mol Cell Proteomics (2009) 8, 258-272. PubMed  Europe PubMed DOI  P
    25. 2008
  25. Chowdhury,D. and Lieberman,J.<br>Death by a thousand cuts: granzyme pathways of programmed cell death<br>Annu Rev Immunol (2008) 26, 389-420. PubMed  Europe PubMed DOI  V
    26. 2007
  26. Cao,X., Cai,S.F., Fehniger,T.A., Song,J., Collins,L.I., Piwnica-Worms,D.R. and Ley,T.J.<br>Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance<br>Immunity (2007) 27, 635-646. PubMed  Europe PubMed DOI  K
  27. Casciola-Rosen,L., Garcia-Calvo,M., Bull,H.G., Becker,J.W., Hines,T., Thornberry,N.A. and Rosen,A.<br>Mouse and human granzyme B have distinct tetrapeptide specificities and abilities to recruit the Bid pathway<br>J Biol Chem (2007) 282, 4545-4552. PubMed  Europe PubMed DOI  P
  28. [YEAR:12-2-2007]Cullen,S.P., Adrain,C., Luthi,A.U., Duriez,P.J. and Martin,S.J.<br>Human and murine granzyme B exhibit divergent substrate preferences<br>J Cell Biol (12-2-2007) 176, 435-444. PubMed  Europe PubMed DOI  PMC  EPMC  P
  29. Pardo,J., Wallich,R., Ebnet,K., Iden,S., Zentgraf,H., Martin,P., Ekiciler,A., Prins,A., Mullbacher,A., Huber,M. and Simon,M.M.<br>Granzyme B is expressed in mouse mast cells in vivo and in vitro and causes delayed cell death independent of perforin<br>Cell Death Differ (2007) 14, 1768-1779. PubMed  Europe PubMed DOI
  30. Thia,K.Y. and Trapani,J.A.<br>The granzyme B gene is highly polymorphic in wild mice but essentially invariant in common inbred laboratory strains<br>Tissue Antigens (2007) 70, 198-204. PubMed  Europe PubMed DOI
    31. 2006
  31. [YEAR:16-1-2006]Adrain,C., Duriez,P.J., Brumatti,G., Delivani,P. and Martin,S.J.<br>The cytotoxic lymphocyte protease, granzyme B, targets the cytoskeleton and perturbs microtubule polymerization dynamics<br>J Biol Chem (16-1-2006) 281, 8118-8125. PubMed  Europe PubMed DOI
    32. 2005
  32. [YEAR:24-3-2005]Blink,E.J., Jiansheng,Z., Hu,W., Calanni,S.T., Trapani,J.A., Bird,P.I. and Jans,D.A.<br>Interaction of the nuclear localizing cytolytic granule serine protease granzyme B with importin alpha or beta: modulation by the serpin inhibitor PI-9<br>J Cell Biochem (24-3-2005) 95, 598-610. PubMed  Europe PubMed DOI
  33. Choy,J.C., Cruz,R.P., Kerjner,A., Geisbrecht,J., Sawchuk,T., Fraser,S.A., Hudig,D., Bleackley,R.C., Jirik,F.R., McManus,B.M. and Granville,D.J.<br>Granzyme B induces endothelial cell apoptosis and contributes to the development of transplant vascular disease<br>Am J Transplant (2005) 5, 494-499. PubMed  Europe PubMed DOI
  34. [YEAR:15-2-2005]Gondek,D.C., Lu,L.F., Quezada,S.A., Sakaguchi,S. and Noelle,R.J.<br>Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism<br>J Immunol (15-2-2005) 174, 1783-1786. PubMed  Europe PubMed
  35. Graham,K.L., Thibault,D.L., Steinman,J.B., Okeke,L., Kao,P.N. and Utz,P.J.<br>Granzyme B is dispensable for immunologic tolerance to self in a murine model of systemic lupus erythematosus<br>Arthritis Rheum (2005) 52, 1684-1693. PubMed  Europe PubMed DOI
  36. [YEAR:4-11-2005]Kurschus,F.C., Bruno,R., Fellows,E., Falk,C.S. and Jenne,D.E.<br>Membrane receptors are not required to deliver granzyme B during killer cell attack<br>Blood (4-11-2005) 105, 2049-2058. PubMed  Europe PubMed DOI
  37. [YEAR:15-2-2005]Revell,P.A., Grossman,W.J., Thomas,D.A., Cao,X., Behl,R., Ratner,J.A., Lu,Z.H. and Ley,T.J.<br>Granzyme B and the downstream granzymes C and/or F are important for cytotoxic lymphocyte functions<br>J Immunol (15-2-2005) 174, 2124-2131. PubMed  Europe PubMed
  38. [YEAR:7-2-2005]Sebbagh,M., Hamelin,J., Bertoglio,J., Solary,E. and Breard,J.<br>Direct cleavage of ROCK II by granzyme B induces target cell membrane blebbing in a caspase-independent manner<br>J Exp Med (7-2-2005) 201, 465-471. PubMed  Europe PubMed DOI  PMC  EPMC
  39. [YEAR:1-12-2005]Waterhouse,N.J., Sedelies,K.A., Browne,K.A., Wowk,M.E., Newbold,A., Sutton,V.R., Clarke,C.J., Oliaro,J., Lindemann,R.K., Bird,P.I., Johnstone,R.W. and Trapani,J.A.<br>A central role for Bid in granzyme B-induced apoptosis<br>J Biol Chem (1-12-2005) 280, 4476-4482. PubMed  Europe PubMed DOI
    40. 2004
  40. Froelich,C.J.<br>Granzyme B<br>[ISSN:0-12-079610-4] (2004) 2, 1549-1552.  V
  41. [YEAR:8-11-2004]Pardo,J., Bosque,A., Brehm,R., Wallich,R., Naval,J., Mullbacher,A., Anel,A. and Simon,M.M.<br>Apoptotic pathways are selectively activated by granzyme A and/or granzyme B in CTL-mediated target cell lysis<br>J Cell Biol (8-11-2004) 167, 457-468. PubMed  Europe PubMed DOI  PMC  EPMC
  42. [YEAR:3-5-2004]Ruggles,S.W., Fletterick,R.J. and Craik,C.S.<br>Characterization of structural determinants of granzyme B reveals potent mediators of extended substrate specificity<br>J Biol Chem (3-5-2004) 279, 30751-30759. PubMed  Europe PubMed DOI
  43. Wowk,M.E. and Trapani,J.A.<br>Cytotoxic activity of the lymphocyte toxin granzyme B<br>Microbes Infect (2004) 6, 752-758. PubMed  Europe PubMed DOI
    44. 2003
  44. Andrade,F., Casciola-Rosen,L.A. and Rosen,A.<br>A novel domain in adenovirus L4-100K is required for stable binding and efficient inhibition of human granzyme B: possible interaction with a species-specific exosite<br>Mol Cell Biol (2003) 23, 6315-6326. PubMed  Europe PubMed DOI  PMC  EPMC
  45. [YEAR:1-5-2003]Ewen,C., Kane,K.P., Shostak,I., Griebel,P.J., Bertram,E.M., Watts,T.H., Bleackley,R.C. and McElhaney,J.E.<br>A novel cytotoxicity assay to evaluate antigen-specific CTL responses using a colorimetric substrate for granzyme B<br>J Immunol Methods (1-5-2003) 276, 89-101. PubMed  Europe PubMed DOI  A
  46. Goping,I.S., Barry,M., Liston,P., Sawchuk,T., Constantinescu,G., Michalak,K.M., Shostak,I., Roberts,D.L., Hunter,A.M., Korneluk,R. and Bleackley,R.C.<br>Granzyme B-induced apoptosis requires both direct caspase activation and relief of caspase inhibition<br>Immunity (2003) 18, 355-365. PubMed  Europe PubMed DOI
  47. Ida,H., Nakashima,T., Kedersha,N.L., Yamasaki,S., Huang,M., Izumi,Y., Miyashita,T., Origuchi,T., Kawakami,A., Migita,K., Bird,P.I., Anderson,P. and Eguchi,K.<br>Granzyme B leakage-induced cell death: a new type of activation-induced natural killer cell death<br>Eur J Immunol (2003) 33, 3284-3292. PubMed  Europe PubMed DOI
  48. [YEAR:4-3-2003]McIlroy,D., Cartron,P.F., Tuffery,P., Dudoit,Y., Samri,A., Autran,B., Vallette,F.M., Debre,P. and Theodorou,I.<br>A triple-mutated allele of granzyme B incapable of inducing apoptosis<br>Proc Natl Acad Sci U S A (4-3-2003) 100, 2562-2567. PubMed  Europe PubMed DOI  PMC  EPMC  M
  49. [YEAR:17-3-2003]Metkar,S.S., Wang,B., Ebbs,M.L., Kim,J.H., Lee,Y.J., Raja,S.M. and Froelich,C.J.<br>Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis<br>J Cell Biol (17-3-2003) 160, 875-885. PubMed  Europe PubMed DOI  PMC  EPMC
  50. [YEAR:5-9-2003]Sattar,R., Ali,S.A. and Abbasi,A.<br>Bioinformatics of granzymes: sequence comparison and structural studies on granzyme family by homology modeling<br>Biochem Biophys Res Commun (5-9-2003) 308, 726-735. PubMed  Europe PubMed DOI
  51. Sutton,V.R., Wowk,M.E., Cancilla,M. and Trapani,J.A.<br>Caspase activation by granzyme B is indirect, and caspase autoprocessing requires the release of proapoptotic mitochondrial factors<br>Immunity (2003) 18, 319-329. PubMed  Europe PubMed DOI
    52. 2001
  52. Davis,J.E., Smyth,M.J. and Trapani,J.A.<br>Granzyme A and B-deficient killer lymphocytes are defective in eliciting DNA fragmentation but retain potent in vivo anti-tumor capacity<br>Eur J Immunol (2001) 31, 39-47. PubMed  Europe PubMed DOI
  53. [YEAR:1-2-2001]Gahring,L.C., Carlson,N.G., Meyer,E.L. and Rogers,S.W.<br>Granzyme B proteolysis of a neuronal glutamate receptor generates an autoantigen and is modulated by glycosylation<br>J Immunol (1-2-2001) 166, 1433-1438. PubMed  Europe PubMed
    54. 2000
  54. Barry,M., Heibein,J.A., Pinkoski,M.J., Lee,S.F., Moyer,R.W., Green,D.R. and Bleackley,R.C.<br>Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving bid<br>Mol Cell Biol (2000) 20, 3781-3794. PubMed  Europe PubMed DOI  PMC  EPMC
  55. [YEAR:5-7-2000]Harris,J.L., Backes,B.J., Leonetti,F., Mahrus,S., Ellman,J.A. and Craik,C.S.<br>Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries<br>Proc Natl Acad Sci U S A (5-7-2000) 97, 7754-7759. PubMed  Europe PubMed DOI  PMC  EPMC  P
  56. [YEAR:7-3-2000]Kam,C.M., Hudig,D. and Powers,J.C.<br>Granzymes (lymphocyte serine proteases): characterization with natural and synthetic substrates and inhibitors<br>Biochim Biophys Acta (7-3-2000) 1477, 307-323. PubMed  Europe PubMed DOI  V
  57. Shi,L., Yang,X., Froelich,C.J. and Greenberg,A.H.<br>Purification and use of granzyme B<br>Methods Enzymol (2000) 322, 125-143. PubMed  Europe PubMed  V
  58. Thomas,D.A., Du,C., Xu,M., Wang,X. and Ley,T.J.<br>DFF45/ICAD can be directly processed by granzyme B during the induction of apoptosis<br>Immunity (2000) 12, 621-632. PubMed  Europe PubMed
  59. Waugh,S.M., Harris,J.L., Fletterick,R. and Craik,C.S.<br>The structure of the pro-apoptotic protease granzyme B reveals the molecular determinants of its specificity<br>Nat Struct Biol (2000) 7, 762-765. PubMed  Europe PubMed DOI  S
    60. 1999
  60. Blink,E.J., Trapani,J.A. and Jans,D.A.<br>Perforin-dependent nuclear targeting of granzymes: A central role in the nuclear events of granule-exocytosis-mediated apoptosis?<br>Immunol Cell Biol (1999) 77, 206-215. PubMed  Europe PubMed DOI
  61. [YEAR:1-6-1999]Caputo,A., Parrish,J.C., James,M.N., Powers,J.C. and Bleackley,R.C.<br>Electrostatic reversal of serine proteinase substrate specificity<br>Proteins (1-6-1999) 35, 415-424. PubMed  Europe PubMed DOI
  62. [YEAR:23-11-1999]Mullbacher,A., Waring,P., Tha Hla,R., Tran,T., Chin,S., Stehle,T., Museteanu,C. and Simon,M.M.<br>Granzymes are the essential downstream effector molecules for the control of primary virus infections by cytolytic leukocytes<br>Proc Natl Acad Sci U S A (23-11-1999) 96, 13950-13955. PubMed  Europe PubMed DOI  PMC  EPMC
    63. 1998
  63. Andrade,F., Roy,S., Nicholson,D., Thornberry,N., Rosen,A. and Casciola-Rosen,L.<br>Granzyme B directly and efficiently cleaves several downstream caspase substrates: Implications for CTL-induced apoptosis<br>Immunity (1998) 8, 451-460. PubMed  Europe PubMed DOI
  64. Bird,C.H., Sutton,V.R., Sun,J., Hirst,C.E., Novak,A., Kumar,S., Trapani,J.A. and Bird,P.I.<br>Selective regulation of apoptosis: the cytotoxic lymphocyte serpin proteinase inhibitor 9 protects against granzyme B-mediated apoptosis without perturbing the Fas cell death pathway<br>Mol Cell Biol (1998) 18, 6387-6398. PubMed  Europe PubMed  PMC  EPMC
  65. [YEAR:16-10-1998]Harris,J.L., Peterson,E.P., Hudig,D., Thornberry,N.A. and Craik,C.S.<br>Definition and redesign of the extended substrate specificity of granzyme B<br>J Biol Chem (16-10-1998) 273, 27364-27373. PubMed  Europe PubMed DOI
  66. [YEAR:16-1-1998]Pham,C.T., Thomas,D.A., Mercer,J.D. and Ley,T.J.<br>Production of fully active recombinant murine granzyme B in yeast<br>J Biol Chem (16-1-1998) 273, 1629-1633. PubMed  Europe PubMed DOI  E  I
  67. [YEAR:13-2-1998]Xia,Z., Kam,C.M., Huang,C., Powers,J.C., Mandle,R.J., Stevens,R.L. and Lieberman,J.<br>Expression and purification of enzymatically active recombinant granzyme B in a baculovirus system<br>Biochem Biophys Res Commun (13-2-1998) 243, 384-389. PubMed  Europe PubMed DOI
  68. [YEAR:18-12-1998]Yang,X., Stennicke,H.R., Wang,B., Green,D.R., Janicke,R.U., Srinivasan,A., Seth,P., Salvesen,G.S. and Froelich,C.J.<br>Granzyme B mimics apical caspases. Description of a unified pathway for trans-activation of executioner caspase-3 and -7<br>J Biol Chem (18-12-1998) 273, 34278-34283. PubMed  Europe PubMed DOI
    69. 1997
  69. Babichuk,C.K. and Bleackley,R.C.<br>Mutational analysis of the murine granzyme B gene promoter in primary T cells and a T cell clone<br>J Biol Chem (1997) 272, 18564-18571. PubMed  Europe PubMed DOI
  70. Hommel-Berrey,G.A., Bochan,M.R., Montel,A.H., Goebel,W.S., Froelich,C.J. and Brahmi,Z.<br>Granzyme B independently of perforin mediates noncytolytic intracellular inactivation of vesicular stomatitis virus<br>Cell Immunol (1997) 180, 1-9. PubMed  Europe PubMed DOI
  71. Talanian,R.V., Yang,X., Turbov,J., Seth,P., Ghayur,T., Casiano,C.A., Orth,K. and Froelich,C.J.<br>Granule-mediated killing: pathways for granzyme B-initiated apoptosis<br>J Exp Med (1997) 186, 1323-1331. PubMed  Europe PubMed DOI  PMC  EPMC
  72. Van de Craen,M., van den Brande,I., Declercq,W., Irmler,M., Beyaert,R., Tschopp,J., Fiers,W. and Vandenabeele,P.<br>Cleavage of caspase family members by granzyme B: a comparative study in vitro<br>Eur J Immunol (1997) 27, 1296-1299. PubMed  Europe PubMed DOI
    73. 1996
  73. [YEAR:12-7-1996]Duan,H., Orth,K., Chinnaiyan,A.M., Poirier,G.G., Froelich,C.J., He,W.W. and Dixit,V.M.<br>ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B<br>J Biol Chem (12-7-1996) 271, 16720-16724. PubMed  Europe PubMed DOI
  74. Gu,Y., Sarnecki,C., Fleming,M.A., Lippke,J.A., Bleackley,R.C. and Su,M.S.<br>Processing and activation of CMH-1 by granzyme B<br>J Biol Chem (1996) 271, 10816-10820. PubMed  Europe PubMed DOI
  75. Martin,S.J., Amarante-Mendes,G.P., Shi,L., Chuang,T.H., Casiano,C.A., O'Brien,G.A., Fitzgerald,P., Tan,E.M., Bokoch,G.M., Greenberg,A.H. and Green,D.R.<br>The cytotoxic cell protease granzyme B initiates apoptosis in a cell-free system by proteolytic processing and activation of the ICE/CED-3 family protease,CPP32, via a novel two- step mechanism<br>EMBO J (1996) 15, 2407-2416. PubMed  Europe PubMed  PMC  EPMC
  76. Quan,L.T., Tewari,M., O'Rourke,K., Dixit,V., Snipas,S.J., Poirier,G.G., Ray,C., Pickup,D.J. and Salvesen,G.S.<br>Proteolytic activation of the cell death protease Yama/CPP32 by granzyme B<br>Proc Natl Acad Sci U S A (1996) 93, 1972-1976. PubMed  Europe PubMed  PMC  EPMC
  77. Smyth,M.J., O'Connor,M.D. and Trapani,J.A.<br>Granzymes: a variety of serine protease specificities encoded by genetically distinct subfamilies<br>J Leukoc Biol (1996) 60, 555-562. PubMed  Europe PubMed  V
    78. 1995
  78. Bochan,M.R., Goebel,W.S. and Brahmi,Z.<br>Stably transfected antisense granzyme B and perforin constructs inhibit human granule-mediated lytic ability<br>Cell Immunol (1995) 164, 234-239. PubMed  Europe PubMed DOI
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