Literature for peptidase S01.133: cathepsin G

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors Pharma

(Topics flags: S Structure, A Assay, T Target, P Specificity, K Knockout, V Review, M Mutation, I Inhibitor, L Localization. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Alzoubi,L., Hamzat,Y., Alqudah,A. and Aljabali,A.A.A.
    The Cathepsin Family in Disease: From Molecular Mechanisms to Therapeutic Applications
    Curr Neuropharmacol (2025) PubMed  Europe PubMed DOI
  2. Kahler,J.P., Coene,J., Skorenski,M., Korovesis,D. and Verhelst,S.H.L.
    Mixed Alkyl Aryl Phosphonates as Quenched Activity-Based Probes for Real-Time Imaging of Active Neutrophil Serine Proteases
    ACS Chem Biol (2025) PubMed  Europe PubMed DOI
  3. Korba-Mikolajczyk,A., Sluzalska,K.D. and Kasperkiewicz,P.
    Exploring the involvement of serine proteases in neutrophil extracellular traps: a review of mechanisms and implications
    Cell Death Dis (2025) 16, 535-535. PubMed  Europe PubMed DOI  PMC  EPMC
  4. Sandri,A. and Boschi,F.
    Exploring Proteases as Alternative Molecular Targets to Tackle Inflammation in Cystic Fibrosis Respiratory Infections
    Int J Mol Sci (2025) 26 PubMed  Europe PubMed DOI  PMC  EPMC  V
  5. Wang,Y., Rozen,V., Dinh,T., Li,H., Li,Y. and Wang,Z.
    CRISPR/Cas9 screenings reveal the role of STX1A and CDK1 in Cathepsin G entering and killing colorectal cancer cells
    bioRxiv (2025) PubMed  Europe PubMed DOI  PMC  EPMC
  6. Wroblewska-Schmude,A., Audzeyenka,I., Mallek,W., Wysocka,M., Lesner,A., Narajczyk,M., Gajdowska,F., Gutowska-Owsiak,D., Kulesza,T., Rogacka,D. and Piwkowska,A.
    Podocytes as novel sources of neutrophil serine proteases: expression and regulation by inflammatory molecular patterns
    Cell Mol Life Sci (2025) PubMed  Europe PubMed DOI
  7. 2024
  8. Akula,S., Tripathi,S.R., Franke,K., Wernersson,S., Babina,M. and Hellman,L.
    Cultures of Human Skin Mast Cells, an Attractive In Vitro Model for Studies of Human Mast Cell Biology
    Cells (2024) 13 PubMed  Europe PubMed DOI  PMC  EPMC
  9. Aliter,K.F. and Al-Horani,R.A.
    Substituted 4H-3,1-benzoxazine-4-one Derivatives as Inhibitors of Cathepsin G
    Med Chem (2024) 20, 944-949. PubMed  Europe PubMed DOI  I
  10. Schuhmann,F., Bordallo,H.N. and Pezeshkian,W.
    Physics-Based Protein Networks Might Recover Effectful Mutations horizontal line a Case Study on Cathepsin G
    J Phys Chem B (2024) PubMed  Europe PubMed DOI
  11. Wang,T., Rathee,A., Pemberton,P.A. and Lood,C.
    Exogenous Serpin B1 restricts Immune complex-mediated NET formation via inhibition of a chymotrypsin-like protease and enhances microbial phagocytosis
    J Biol Chem (2024) , 107533-107533. PubMed  Europe PubMed DOI
  12. 2023
  13. Bencosme-Cuevas,E., Kim,T.K., Nguyen,T.T., Berry,J., Li,J., Adams,L.G., Smith,L.A., Batool,S.A., Swale,D.R., Kaufmann,S.H.E., Jones-Hall,Y. and Mulenga,A.
    Ixodes scapularis nymph saliva protein blocks host inflammation and complement-mediated killing of Lyme disease agent, Borrelia burgdorferi
    Front Cell Infect Microbiol (2023) 13, 1253670-1253670. PubMed  Europe PubMed DOI  PMC  EPMC
  14. Carnevale,R., Leopizzi,M., Dominici,M., D'Amati,G., Bartimoccia,S., Nocella,C., Cammisotto,V., D'Amico,A., Castellani,V., Baratta,F., Bertelli,A., Arrivi,A., Toni,D., De Michele,M., Pignatelli,P., Marcucci,R. and Violi,F.
    PAD4-Induced NETosis Via Cathepsin G-Mediated Platelet-Neutrophil Interaction in ChAdOx1 Vaccine-Induced Thrombosis-Brief Report
    Arterioscler Thromb Vasc Biol (2023) 43, e396-e396. PubMed  Europe PubMed DOI
  15. Mishra,N., Herdendorf,T.J., Prakash,O. and Geisbrecht,B.V.
    Simultaneous inhibition of two neutrophil serine proteases by the S. aureus innate immune evasion protein EapH2
    J Biol Chem (2023) 299, 104878-104878. PubMed  Europe PubMed DOI  PMC  EPMC
  16. Willows,S.D., Semenchenko,V., Norman,G., Woodside,M.T., Sim,V.L. and Kulka,M.
    Mast Cell Proteases Cleave Prion Proteins and a Recombinant Ig against PrP Can Activate Human Mast Cells
    J Immunol (2023) 210, 1447-1458. PubMed  Europe PubMed DOI
  17. 2022
  18. Basso,J., Zhang,J., Lasala,D., Rose,S.J., Chen,K.J. and Cipolla,D.
    An optimized method of extracting and quantifying active Neutrophil serine proteases from human whole blood cells
    PLoS ONE (2022) 17, e0272575-e0272575. PubMed  Europe PubMed DOI  PMC  EPMC
  19. Gomez-Alonso,I.S., Martinez-Garcia,S., Betanzos-Cabrera,G., Juarez,E., Sarabia-Leon,M.C., Herrera,M.T., Gomez-Chavez,F., Sanchez-Torres,L., Rodriguez-Martinez,S., Cancino-Diaz,M.E., Cancino,J. and Cancino-Diaz,J.C.
    Low Concentration of the Neutrophil Proteases Cathepsin G, Cathepsin B, Proteinase-3 and Metalloproteinase-9 Induce Biofilm Formation in Non-Biofilm-Forming Staphylococcus epidermidis Isolates
    Int J Mol Sci (2022) 23 PubMed  Europe PubMed DOI  PMC  EPMC
  20. Hao,P., Li,H., Zhou,L., Sun,H., Han,J. and Zhang,Z.
    Serum Metal Ion-Induced Cross-Linking of Photoelectrochemical Peptides and Circulating Proteins for Evaluating Cardiac Ischemia/Reperfusion
    ACS Sens (2022) 7, 775-783. PubMed  Europe PubMed DOI
  21. Li,B.Y., Guo,Y.Y., Xiao,G., Guo,L. and Tang,Q.Q.
    SERPINA3C ameliorates adipose tissue inflammation through the Cathepsin G/Integrin/AKT pathway
    Mol Metab (2022) 61, 101500-101500. PubMed  Europe PubMed DOI  PMC  EPMC
  22. Mustafa,Z., Kalbacher,H. and Burster,T.
    Occurrence of a novel cleavage site for cathepsin G adjacent to the polybasic sequence within the proteolytically sensitive activation loop of the SARS-CoV-2 Omicron variant: The amino acid substitution N679K and P681H of the spike protein
    PLoS ONE (2022) 17, e0264723-e0264723. PubMed  Europe PubMed DOI  PMC  EPMC
  23. 2021
  24. Burster,T., Gartner,F., Knippschild,U. and Zhanapiya,A.
    Activity-Based Probes to Utilize the Proteolytic Activity of Cathepsin G in Biological Samples
    Front Chem (2021) 9, 628295-628295. PubMed  Europe PubMed DOI  PMC  EPMC
  25. Cheung,P., Schaffert,S., Chang,S.E., Dvorak,M., Donato,M., Macaubas,C., Foecke,M.H., Li,T.M., Zhang,L., Coan,J.P., Schulert,G.S., Grom,A.A., Henderson,L.A., Nigrovic,P.A., Elias,J.E., Gozani,O., Mellins,E.D., Khatri,P., Utz,P.J. and Kuo,A.J.
    Repression of CTSG, ELANE and PRTN3-mediated histone H3 proteolytic cleavage promotes monocyte-to-macrophage differentiation
    Nat Immunol (2021) 22, 711-722. PubMed  Europe PubMed DOI  PMC  EPMC
  26. El-Kalioby,M., El-Komy,M.H.M., Said,E.R., Amer,M.A., Saadi,D.G., Nouredin Mohammed,F., Rashed,L.A., El Desouky,E.D. and AlOrbani,A.M.
    Downregulation of interleukin 36gamma and its cleaver cathepsin G following treatment with narrow-band ultraviolet B phototherapy in psoriasis vulgaris
    J Dermatolog Treat (2021) , 1-6. PubMed  Europe PubMed DOI
  27. Fazleen,A. and Wilkinson,T.
    The emerging role of proteases in alpha1-antitrypsin deficiency and beyond
    ERJ Open Res (2021) 7 PubMed  Europe PubMed DOI  PMC  EPMC
  28. Fischer,A., Sellner,M., Mitusinska,K., Bzowka,M., Lill,M.A., Gora,A. and Smiesko,M.
    Computational Selectivity Assessment of Protease Inhibitors against SARS-CoV-2
    Int J Mol Sci (2021) 22 PubMed  Europe PubMed DOI  PMC  EPMC
  29. Frey,D.L., Guerra,M., Mall,M.A. and Schultz,C.
    Monitoring Neutrophil Elastase and Cathepsin G Activity in Human Sputum Samples
    J Vis Exp (2021) PubMed  Europe PubMed DOI
  30. Huang,G.Z., Wu,Q.Q., Zheng,Z.N., Shao,T.R., Li,F., Lu,X.Y., Ye,H.Y., Chen,G.X., Song,Y.X., Zeng,W.S., Ai,Y.L. and Lv,X.Z.
    Bioinformatics Analyses Indicate That Cathepsin G (CTSG) is a Potential Immune-Related Biomarker in Oral Squamous Cell Carcinoma (OSCC)
    Onco Targets Ther (2021) 14, 1275-1289. PubMed  Europe PubMed DOI  PMC  EPMC
  31. Huang,S., Thomsson,K.A., Jin,C., Alweddi,S., Struglics,A., Rolfson,O., Bjorkman,L.I., Kalamajski,S., Schmidt,T.A., Jay,G.D., Krawetz,R., Karlsson,N.G. and Eisler,T.
    Author Correction: Cathepsin G Degrades Both Glycosylated and Unglycosylated Regions of Lubricin, a Synovial Mucin
    Sci Rep (2021) 11, 4238-4238. PubMed  Europe PubMed DOI  PMC  EPMC
  32. Leinweber,J., Mizurini,D.M., Francischetti,I.M.B., Fleischer,M., Hermann,D.M., Kleinschnitz,C. and Langhauser,F.
    Elastase inhibitor agaphelin protects from acute ischemic stroke in mice by reducing thrombosis, blood-brain barrier damage, and inflammation
    Brain Behav Immun (2021) PubMed  Europe PubMed DOI
  33. Valois,M.V., de Oliveira,C., Lapa,A.J., Souccar,C. and Oliva,M.L.V.
    Bauhinia Protease Inhibitors Attenuate Gastric Ulcer by Blocking Neutrophil Enzymes
    Planta Med (2021) 87, 169-176. PubMed  Europe PubMed DOI
  34. Weiss,S.A.I., Rehm,S.R.T., Perera,N.C., Biniossek,M.L., Schilling,O. and Jenne,D.E.
    Origin and Expansion of the Serine Protease Repertoire in the Myelomonocyte Lineage
    Int J Mol Sci (2021) 22 PubMed  Europe PubMed DOI  PMC  EPMC
  35. 2020
  36. Akgun,E., Tuzuner,M.B., Sahin,B., Kilercik,M., Kulah,C., Cakiroglu,H.N., Serteser,M., Unsal,I. and Baykal,A.T.
    Proteins associated with neutrophil degranulation are upregulated in nasopharyngeal swabs from SARS-CoV-2 patients
    PLoS ONE (2020) 15, e0240012-e0240012. PubMed  Europe PubMed DOI  PMC  EPMC
  37. Amaral,A., Fernandes,C., Morazzo,S., Rebordao,M.R., Szostek-Mioduchowska,A., Lukasik,K., Gawronska-Kozak,B., Telo da Gama,L., Skarzynski,D.J. and Ferreira-Dias,G.
    The Inhibition of Cathepsin G on Endometrial Explants With Endometrosis in the Mare
    Front Vet Sci (2020) 7, 582211-582211. PubMed  Europe PubMed DOI  PMC  EPMC
  38. Gartner,F., Knippschild,U. and Burster,T.
    Application of an Activity-Based Probe to Determine Proteolytic Activity of Cell Surface Cathepsin G by Mass Cytometry Data Acquisition
    ACS Omega (2020) 5, 28233-28238. PubMed  Europe PubMed DOI  PMC  EPMC  I
  39. Guerra,M., Halls,V.S., Schatterny,J., Hagner,M., Mall,M.A. and Schultz,C.
    Protease FRET Reporters Targeting Neutrophil Extracellular Traps
    J Am Chem Soc (2020) PubMed  Europe PubMed DOI
  40. Huang,S., Thomsson,K.A., Jin,C., Alweddi,S., Struglics,A., Rolfson,O., Bjorkman,L.I., Kalamajski,S., Schmidt,T.A., Jay,G.D., Krawetz,R., Karlsson,N.G. and Eisler,T.
    Cathepsin G degrades both glycosylated and unglycosylated regions of lubricin, a synovial mucin
    Sci Rep (2020) 10, 4215-4215. PubMed  Europe PubMed DOI  PMC  EPMC
  41. Morimoto-Kamata,R., Tsuji,D. and Yui,S.
    Cathepsin G-Induced Insulin-Like Growth Factor (IGF) Elevation in MCF-7 Medium Is Caused by Proteolysis of IGF Binding Protein (IGFBP)-2 but Not of IGF-1
    Biol Pharm Bull (2020) 43, 1678-1686. PubMed  Europe PubMed DOI
  42. Sanchez Di Maggio,L., Tirloni,L., Uhl,M., Carmona,C., Logullo,C., Mulenga,A., da Silva,V.I., Jr. and Berasain,P.
    Serpins in Fasciola hepatica: insights into host-parasite interactions
    Int J Parasitol (2020) PubMed  Europe PubMed DOI
  43. Schroeder,R., Grzywa,R., Wirtz,C.R., Sienczyk,M. and Burster,T.
    Application of a novel FAM-conjugated activity-based probe to determine cathepsin G activity intracellularly
    Anal Biochem (2020) 588, 113488-113488. PubMed  Europe PubMed DOI  L
  44. Sowinska,A., Rensing,M., Klevenvall,L., Neog,M., Lundback,P. and Harris,H.E.
    Cleavage of HMGB1 by Proteolytic Enzymes Associated with Inflammatory Conditions
    Front Immunol (2020) 11, 448262-448262. PubMed  Europe PubMed DOI  PMC  EPMC
  45. Voynow,J.A., Zheng,S. and Kummarapurugu,A.B.
    Glycosaminoglycans as Multifunctional Anti-Elastase and Anti-Inflammatory Drugs in Cystic Fibrosis Lung Disease
    Front Pharmacol (2020) 11, 1011-1011. PubMed  Europe PubMed DOI  PMC  EPMC
  46. Zamolodchikova,T.S., Tolpygo,S.M. and Svirshchevskaya,E.V.
    Cathepsin G - not only inflammation: the immune protease can regulate normal physiological processes
    Front Immunol (2020) 11, 411-411. PubMed  Europe PubMed DOI  PMC  EPMC
  47. 2019
  48. Aghdassi,A.A., John,D.S., Sendler,M., Storck,C., van den Brandt,C., Kruger,B., Weiss,F.U., Mayerle,J. and Lerch,M.M.
    Absence of the neutrophil serine protease cathepsin G decreases neutrophil granulocyte infiltration but does not change the severity of acute pancreatitis
    Sci Rep (2019) 9, 16774-16774. PubMed  Europe PubMed DOI
  49. Burgener,S.S., Leborgne,N.G.F., Snipas,S.J., Salvesen,G.S., Bird,P.I. and Benarafa,C.
    Cathepsin G inhibition by serpinb1 and serpinb6 prevents programmed necrosis in neutrophils and monocytes and reduces GSDMD-driven inflammation
    Cell Rep (2019) 27, 3646-3656. PubMed  Europe PubMed DOI
  50. Groborz,K., Kolt,S., Kasperkiewicz,P. and Drag,M.
    Internally quenched fluorogenic substrates with unnatural amino acids for cathepsin G investigation
    Biochimie (2019) 166, 103-111. PubMed  Europe PubMed DOI  A
  51. Guerra,M., Frey,D., Hagner,M., Dittrich,S., Paulsen,M., Mall,M.A. and Schultz,C.
    Cathepsin G activity as a new marker for detecting airway inflammation by microscopy and flow cytometry
    ACS Cent Sci (2019) 5, 539-548. PubMed  Europe PubMed DOI  PMC  EPMC
  52. Guo,J., Tu,J., Hu,Y., Song,G. and Yin,Z.
    Cathepsin G cleaves and activates IL-36gamma and promotes the inflammation of psoriasis
    Drug Des Devel Ther (2019) 13, 581-588. PubMed  Europe PubMed DOI  PMC  EPMC
  53. Kish,D.D., Min,S., Dvorina,N., Baldwin WM 3rd, Stohlman,S.A. and Fairchild,R.L.
    Neutrophil cathepsin G regulates dendritic cell production of IL-12 during development of CD4 T cell responses to antigens in the skin
    J Immunol (2019) 202, 1045-1056. PubMed  Europe PubMed DOI  K
  54. Krasavin,M.Y., Gureev,M.A., Garabadzhiu,A.V., Pashkin,A.Y., Zhukov,A.S., Khairutdinov,V.R., Samtsov,A.V. and Shvets,V.I.
    Inhibition of neutrophil elastase and cathepsin G as a new approach to the treatment of psoriasis: from fundamental biology to development of new target-specific drugs
    Dokl Biochem Biophys (2019) 487, 272-276. PubMed  Europe PubMed DOI  I
  55. Kusumaningrum,N., Oh,J.H., Lee,D.H., Shin,C.Y., Jang,J.H., Kim,Y.K. and Chung,J.H.
    Topical treatment with a cathepsin G inhibitor, beta-keto-phosphonic acid, blocks ultraviolet irradiation-induced basement membrane damage in hairless mouse skin
    Photodermatol Photoimmunol Photomed (2019) 35, 148-156. PubMed  Europe PubMed DOI  I
  56. Miller,S.A., Kolpakov,M.A., Guo,X., Du,B., Nguyen,Y., Wang,T., Powel,P., Dell'Italia,L.J. and Sabri,A.
    Intracardiac administration of neutrophil protease cathepsin G activates noncanonical inflammasome pathway and promotes inflammation and pathological remodeling in non-injured heart
    J Mol Cell Cardiol (2019) 134, 29-39. PubMed  Europe PubMed DOI
  57. Penczek,A. and Burster,T.
    Cell surface cathepsin G can be used as an additional marker to distinguish T cell subsets
    Biomed Rep (2019) 10, 245-249. PubMed  Europe PubMed DOI  PMC  EPMC
  58. Sionov,R.V., Fainsod-Levi,T., Zelter,T., Polyansky,L., Pham,C.T. and Granot,Z.
    Neutrophil cathepsin G and tumor cell RAGE facilitate neutrophil anti-tumor cytotoxicity
    Oncoimmunology (2019) 8, e1624129-e1624129. PubMed  Europe PubMed DOI  PMC  EPMC
  59. 2018
  60. Folco,E.J., Mawson,T.L., Vromman,A., Bernardes-Souza,B., Franck,G., Persson,O., Nakamura,M., Newton,G., Luscinskas,F.W. and Libby,P.
    Neutrophil extracellular traps induce endothelial cell activation and tissue factor production through interleukin-1alpha and cathepsin G
    Arterioscler Thromb Vasc Biol (2018) 38, 1901-1912. PubMed  Europe PubMed DOI
  61. Gudmann,N.S., Manon-Jensen,T., Sand,J.M.B., Diefenbach,C., Sun,S., Danielsen,A., Karsdal,M.A. and Leeming,D.J.
    Lung tissue destruction by proteinase 3 and cathepsin G mediated elastin degradation is elevated in chronic obstructive pulmonary disease
    Biochem Biophys Res Commun (2018) 503, 1284-1290. PubMed  Europe PubMed DOI
  62. Jun,H.K., Jung,Y.J., Ji,S., An,S.J. and Choi,B.K.
    Caspase-4 activation by a bacterial surface protein is mediated by cathepsin G in human gingival fibroblasts
    Cell Death Differ (2018) 25, 380-391. PubMed  Europe PubMed DOI
  63. Nguyen,M.T.N., Shema,G., Zahedi,R.P. and Verhelst,S.H.L.
    Protease specificity profiling in a pipet tip using "charge-synchronized" proteome-derived peptide libraries
    J Proteome Res (2018) 17, 1923-1933. PubMed  Europe PubMed DOI  P
  64. Seif,K., Alidzanovic,L., Tischler,B., Ibrahim,N., Zagrapan,B., Rauscher,S., Salzmann,M., Hell,L., Mauracher,L.M., Budde,U., Schmid,J.A., Jilma,B., Pabinger,I., Assinger,A., Starlinger,P. and Brostjan,C.
    Neutrophil-mediated proteolysis of thrombospondin-1 promotes platelet adhesion and string formation
    Thromb Haemost (2018) 118, 2074-2085. PubMed  Europe PubMed DOI
  65. Thorpe,M., Fu,Z., Chahal,G., Akula,S., Kervinen,J., de Garavilla,L. and Hellman,L.
    Extended cleavage specificity of human neutrophil cathepsin G: a low activity protease with dual chymase and tryptase-type specificities
    PLoS ONE (2018) 13, e0195077-e0195077. PubMed  Europe PubMed DOI  P
  66. 2017
  67. Benarafa,C. and Simon,H.U.
    Role of granule proteases in the life and death of neutrophils
    Biochem Biophys Res Commun (2017) 482, 473-481. PubMed  Europe PubMed DOI  V
  68. Fu,Z., Thorpe,M., Alemayehu,R., Roy,A., Kervinen,J., de Garavilla,L., Abrink,M. and Hellman,L.
    Highly selective cleavage of cytokines and chemokines by the human mast cell chymase and neutrophil cathepsin G
    J Immunol (2017) 198, 1474-1483. PubMed  Europe PubMed DOI  P
  69. Khan,M., Carmona,S., Sukhumalchandra,P., Roszik,J., Philips,A., Perakis,A.A., Kerros,C., Zhang,M., Qiao,N., John,L.S.S., Zope,M., Goldberg,J., Qazilbash,M., Jakher,H., Clise-Dwyer,K., Qiu,Y., Mittendorf,E.A., Molldrem,J.J., Kornblau,S.M. and Alatrash,G.
    Cathepsin G is expressed by acute lymphoblastic leukemia and is a potential immunotherapeutic target
    Front Immunol (2017) 8, 1975-1975. PubMed  Europe PubMed DOI  PMC  EPMC  T
  70. Morimoto-Kamata,R. and Yui,S.
    Insulin-like growth factor-1 signaling is responsible for cathepsin G-induced aggregation of breast cancer MCF-7 cells
    Cancer Sci (2017) 108, 1574-1583. PubMed  Europe PubMed DOI
  71. Swedberg,J.E., Li,C.Y., de Veer,S.J., Wang,C.K. and Craik,D.J.
    Design of potent and selective cathepsin G inhibitors based on the sunflower trypsin inhibitor-1 scaffold
    J Med Chem (2017) 60, 658-667. PubMed  Europe PubMed DOI  P
  72. Valayer,A., Brea,D., Lajoie,L., Avezard,L., Combes-Soia,L., Labas,V., Korkmaz,B., Thibault,G., Baranek,T. and Si-Tahar,M.
    Neutrophils can disarm NK cell response through cleavage of NKp46
    J Leukoc Biol (2017) 101, 253-259. PubMed  Europe PubMed DOI
  73. Woo,S.M., Min,K.J., Seo,S.U., Kim,S., Park,J.W., Song,D.K., Lee,H.S., Kim,S.H. and Kwon,T.K.
    Up-regulation of 5-lipoxygenase by inhibition of cathepsin G enhances TRAIL-induced apoptosis through down-regulation of survivin
    Oncotarget (2017) 8, 106672-106684. PubMed  Europe PubMed DOI  PMC  EPMC  I
  74. 2016
  75. Craciun,I., Fenner,A.M. and Kerns,R.J.
    N-Arylacyl O-sulfonated aminoglycosides as novel inhibitors of human neutrophil elastase, cathepsin G and proteinase 3
    Glycobiology (2016) 26, 701-709. PubMed  Europe PubMed DOI  I
  76. Eipper,S., Steiner,R., Lesner,A., Sienczyk,M., Palesch,D., Halatsch,M.E., Zaczynska,E., Heim,C., Hartmann,M.D., Zimecki,M., Wirtz,C.R. and Burster,T.
    Lactoferrin is an allosteric enhancer of the proteolytic activity of cathepsin G
    PLoS ONE (2016) 11, e0151509-e0151509. PubMed  Europe PubMed DOI  PMC  EPMC
  77. Giese,M., Turiello,N., Molenda,N., Palesch,D., Meid,A., Schroeder,R., Basilico,P., Benarafa,C., Halatsch,M.E., Zimecki,M., Westhoff,M.A., Wirtz,C.R. and Burster,T.
    Exogenous cathepsin G upregulates cell surface MHC class I molecules on immune and glioblastoma cells
    Oncotarget (2016) 7, 74602-74611. PubMed  Europe PubMed DOI
  78. Ortega-Gomez,A., Salvermoser,M., Rossaint,J., Pick,R., Brauner,J., Lemnitzer,P., Tilgner,J., de Jong,R.J., Megens,R.T., Jamasbi,J., Doring,Y., Pham,C.T., Scheiermann,C., Siess,W., Drechsler,M., Weber,C., Grommes,J., Zarbock,A., Walzog,B. and Soehnlein,O.
    Cathepsin G controls arterial but not venular myeloid cell recruitment
    Circulation (2016) 134, 1176-1188. PubMed  Europe PubMed DOI
  79. Palesch,D., Wagner,J., Meid,A., Molenda,N., Sienczyk,M., Burkhardt,J., Munch,J., Prokop,L., Stevanovic,S., Westhoff,M.A., Halatsch,M.E., Wirtz,C.R., Zimecki,M. and Burster,T.
    Cathepsin G-mediated proteolytic degradation of MHC class I molecules to facilitate immune detection of human glioblastoma cells
    Cancer Immunol Immunother (2016) 65, 283-291. PubMed  Europe PubMed DOI
  80. Penczek,A., Sienczyk,M., Wirtz,C.R. and Burster,T.
    Cell surface cathepsin G activity differs between human natural killer cell subsets
    Immunol Lett (2016) 179, 80-84. PubMed  Europe PubMed DOI  L
  81. 2015
  82. Liu,X., Tian,Y., Meng,Z., Chen,Y., Ho,I.H., Choy,K.W., Lichtner,P., Wong,S.H., Yu,J., Gin,T., Wu,W.K., Cheng,C.H. and Chan,M.T.
    Up-regulation of cathepsin G in the development of chronic postsurgical pain: an experimental and clinical genetic study
    Anesthesiology (2015) 123, 838-850. PubMed  Europe PubMed DOI  M  I
  83. Loke,I., Packer,N.H. and Thaysen-Andersen,M.
    Complementary LC-MS/MS-based N-glycan, N-glycopeptide, and intact N-glycoprotein profiling reveals unconventional Asn71-glycosylation of human neutrophil cathepsin G
    Biomolecules (2015) 5, 1832-1854. PubMed  Europe PubMed DOI
  84. Mingli,Y., Zhuo,Z. and Jin,Z.
    The role of cathepsin G in the diagnosis and immunotherapy of acute myeloid leukemia
    J Leuk Lymphoma (2015) 24, 190-192. DOI  V
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