Literature for peptidase S01.133: cathepsin G

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: S Structure, A Assay, T Target, P Specificity, K Knockout, V Review, M Mutation, I Inhibitor, L Localization. To select only the references relevant to a single topic, click the link above. See explanation.)

2025

Alzoubi,L., Hamzat,Y., Alqudah,A. and Aljabali,A.A.A. The Cathepsin Family in Disease: From Molecular Mechanisms to Therapeutic Applications Curr Neuropharmacol (2025) PubMed Europe PubMed DOI
Kahler,J.P., Coene,J., Skorenski,M., Korovesis,D. and Verhelst,S.H.L. Mixed Alkyl Aryl Phosphonates as Quenched Activity-Based Probes for Real-Time Imaging of Active Neutrophil Serine Proteases ACS Chem Biol (2025) PubMed Europe PubMed DOI
Korba-Mikolajczyk,A., Sluzalska,K.D. and Kasperkiewicz,P. Exploring the involvement of serine proteases in neutrophil extracellular traps: a review of mechanisms and implications Cell Death Dis (2025) 16, 535-535. PubMed Europe PubMed DOI PMC EPMC
Sandri,A. and Boschi,F. Exploring Proteases as Alternative Molecular Targets to Tackle Inflammation in Cystic Fibrosis Respiratory Infections Int J Mol Sci (2025) 26 PubMed Europe PubMed DOI PMC EPMC V
Wang,Y., Rozen,V., Dinh,T., Li,H., Li,Y. and Wang,Z. CRISPR/Cas9 screenings reveal the role of STX1A and CDK1 in Cathepsin G entering and killing colorectal cancer cells bioRxiv (2025) PubMed Europe PubMed DOI PMC EPMC
Wroblewska-Schmude,A., Audzeyenka,I., Mallek,W., Wysocka,M., Lesner,A., Narajczyk,M., Gajdowska,F., Gutowska-Owsiak,D., Kulesza,T., Rogacka,D. and Piwkowska,A. Podocytes as novel sources of neutrophil serine proteases: expression and regulation by inflammatory molecular patterns Cell Mol Life Sci (2025) PubMed Europe PubMed DOI

2024

Akula,S., Tripathi,S.R., Franke,K., Wernersson,S., Babina,M. and Hellman,L. Cultures of Human Skin Mast Cells, an Attractive In Vitro Model for Studies of Human Mast Cell Biology Cells (2024) 13 PubMed Europe PubMed DOI PMC EPMC
Aliter,K.F. and Al-Horani,R.A. Substituted 4H-3,1-benzoxazine-4-one Derivatives as Inhibitors of Cathepsin G Med Chem (2024) 20, 944-949. PubMed Europe PubMed DOI I
Schuhmann,F., Bordallo,H.N. and Pezeshkian,W. Physics-Based Protein Networks Might Recover Effectful Mutations horizontal line a Case Study on Cathepsin G J Phys Chem B (2024) PubMed Europe PubMed DOI
Wang,T., Rathee,A., Pemberton,P.A. and Lood,C. Exogenous Serpin B1 restricts Immune complex-mediated NET formation via inhibition of a chymotrypsin-like protease and enhances microbial phagocytosis J Biol Chem (2024) , 107533-107533. PubMed Europe PubMed DOI

2023

Bencosme-Cuevas,E., Kim,T.K., Nguyen,T.T., Berry,J., Li,J., Adams,L.G., Smith,L.A., Batool,S.A., Swale,D.R., Kaufmann,S.H.E., Jones-Hall,Y. and Mulenga,A. Ixodes scapularis nymph saliva protein blocks host inflammation and complement-mediated killing of Lyme disease agent, Borrelia burgdorferi Front Cell Infect Microbiol (2023) 13, 1253670-1253670. PubMed Europe PubMed DOI PMC EPMC
Carnevale,R., Leopizzi,M., Dominici,M., D'Amati,G., Bartimoccia,S., Nocella,C., Cammisotto,V., D'Amico,A., Castellani,V., Baratta,F., Bertelli,A., Arrivi,A., Toni,D., De Michele,M., Pignatelli,P., Marcucci,R. and Violi,F. PAD4-Induced NETosis Via Cathepsin G-Mediated Platelet-Neutrophil Interaction in ChAdOx1 Vaccine-Induced Thrombosis-Brief Report Arterioscler Thromb Vasc Biol (2023) 43, e396-e396. PubMed Europe PubMed DOI
Mishra,N., Herdendorf,T.J., Prakash,O. and Geisbrecht,B.V. Simultaneous inhibition of two neutrophil serine proteases by the S. aureus innate immune evasion protein EapH2 J Biol Chem (2023) 299, 104878-104878. PubMed Europe PubMed DOI PMC EPMC
Willows,S.D., Semenchenko,V., Norman,G., Woodside,M.T., Sim,V.L. and Kulka,M. Mast Cell Proteases Cleave Prion Proteins and a Recombinant Ig against PrP Can Activate Human Mast Cells J Immunol (2023) 210, 1447-1458. PubMed Europe PubMed DOI

2022

Basso,J., Zhang,J., Lasala,D., Rose,S.J., Chen,K.J. and Cipolla,D. An optimized method of extracting and quantifying active Neutrophil serine proteases from human whole blood cells PLoS ONE (2022) 17, e0272575-e0272575. PubMed Europe PubMed DOI PMC EPMC
Gomez-Alonso,I.S., Martinez-Garcia,S., Betanzos-Cabrera,G., Juarez,E., Sarabia-Leon,M.C., Herrera,M.T., Gomez-Chavez,F., Sanchez-Torres,L., Rodriguez-Martinez,S., Cancino-Diaz,M.E., Cancino,J. and Cancino-Diaz,J.C. Low Concentration of the Neutrophil Proteases Cathepsin G, Cathepsin B, Proteinase-3 and Metalloproteinase-9 Induce Biofilm Formation in Non-Biofilm-Forming Staphylococcus epidermidis Isolates Int J Mol Sci (2022) 23 PubMed Europe PubMed DOI PMC EPMC
Hao,P., Li,H., Zhou,L., Sun,H., Han,J. and Zhang,Z. Serum Metal Ion-Induced Cross-Linking of Photoelectrochemical Peptides and Circulating Proteins for Evaluating Cardiac Ischemia/Reperfusion ACS Sens (2022) 7, 775-783. PubMed Europe PubMed DOI
Li,B.Y., Guo,Y.Y., Xiao,G., Guo,L. and Tang,Q.Q. SERPINA3C ameliorates adipose tissue inflammation through the Cathepsin G/Integrin/AKT pathway Mol Metab (2022) 61, 101500-101500. PubMed Europe PubMed DOI PMC EPMC
Mustafa,Z., Kalbacher,H. and Burster,T. Occurrence of a novel cleavage site for cathepsin G adjacent to the polybasic sequence within the proteolytically sensitive activation loop of the SARS-CoV-2 Omicron variant: The amino acid substitution N679K and P681H of the spike protein PLoS ONE (2022) 17, e0264723-e0264723. PubMed Europe PubMed DOI PMC EPMC

2021

Burster,T., Gartner,F., Knippschild,U. and Zhanapiya,A. Activity-Based Probes to Utilize the Proteolytic Activity of Cathepsin G in Biological Samples Front Chem (2021) 9, 628295-628295. PubMed Europe PubMed DOI PMC EPMC
Cheung,P., Schaffert,S., Chang,S.E., Dvorak,M., Donato,M., Macaubas,C., Foecke,M.H., Li,T.M., Zhang,L., Coan,J.P., Schulert,G.S., Grom,A.A., Henderson,L.A., Nigrovic,P.A., Elias,J.E., Gozani,O., Mellins,E.D., Khatri,P., Utz,P.J. and Kuo,A.J. Repression of CTSG, ELANE and PRTN3-mediated histone H3 proteolytic cleavage promotes monocyte-to-macrophage differentiation Nat Immunol (2021) 22, 711-722. PubMed Europe PubMed DOI PMC EPMC
El-Kalioby,M., El-Komy,M.H.M., Said,E.R., Amer,M.A., Saadi,D.G., Nouredin Mohammed,F., Rashed,L.A., El Desouky,E.D. and AlOrbani,A.M. Downregulation of interleukin 36gamma and its cleaver cathepsin G following treatment with narrow-band ultraviolet B phototherapy in psoriasis vulgaris J Dermatolog Treat (2021) , 1-6. PubMed Europe PubMed DOI
Fazleen,A. and Wilkinson,T. The emerging role of proteases in alpha1-antitrypsin deficiency and beyond ERJ Open Res (2021) 7 PubMed Europe PubMed DOI PMC EPMC
Fischer,A., Sellner,M., Mitusinska,K., Bzowka,M., Lill,M.A., Gora,A. and Smiesko,M. Computational Selectivity Assessment of Protease Inhibitors against SARS-CoV-2 Int J Mol Sci (2021) 22 PubMed Europe PubMed DOI PMC EPMC
Frey,D.L., Guerra,M., Mall,M.A. and Schultz,C. Monitoring Neutrophil Elastase and Cathepsin G Activity in Human Sputum Samples J Vis Exp (2021) PubMed Europe PubMed DOI
Huang,G.Z., Wu,Q.Q., Zheng,Z.N., Shao,T.R., Li,F., Lu,X.Y., Ye,H.Y., Chen,G.X., Song,Y.X., Zeng,W.S., Ai,Y.L. and Lv,X.Z. Bioinformatics Analyses Indicate That Cathepsin G (CTSG) is a Potential Immune-Related Biomarker in Oral Squamous Cell Carcinoma (OSCC) Onco Targets Ther (2021) 14, 1275-1289. PubMed Europe PubMed DOI PMC EPMC
Huang,S., Thomsson,K.A., Jin,C., Alweddi,S., Struglics,A., Rolfson,O., Bjorkman,L.I., Kalamajski,S., Schmidt,T.A., Jay,G.D., Krawetz,R., Karlsson,N.G. and Eisler,T. Author Correction: Cathepsin G Degrades Both Glycosylated and Unglycosylated Regions of Lubricin, a Synovial Mucin Sci Rep (2021) 11, 4238-4238. PubMed Europe PubMed DOI PMC EPMC
Leinweber,J., Mizurini,D.M., Francischetti,I.M.B., Fleischer,M., Hermann,D.M., Kleinschnitz,C. and Langhauser,F. Elastase inhibitor agaphelin protects from acute ischemic stroke in mice by reducing thrombosis, blood-brain barrier damage, and inflammation Brain Behav Immun (2021) PubMed Europe PubMed DOI
Valois,M.V., de Oliveira,C., Lapa,A.J., Souccar,C. and Oliva,M.L.V. Bauhinia Protease Inhibitors Attenuate Gastric Ulcer by Blocking Neutrophil Enzymes Planta Med (2021) 87, 169-176. PubMed Europe PubMed DOI
Weiss,S.A.I., Rehm,S.R.T., Perera,N.C., Biniossek,M.L., Schilling,O. and Jenne,D.E. Origin and Expansion of the Serine Protease Repertoire in the Myelomonocyte Lineage Int J Mol Sci (2021) 22 PubMed Europe PubMed DOI PMC EPMC

2020

Akgun,E., Tuzuner,M.B., Sahin,B., Kilercik,M., Kulah,C., Cakiroglu,H.N., Serteser,M., Unsal,I. and Baykal,A.T. Proteins associated with neutrophil degranulation are upregulated in nasopharyngeal swabs from SARS-CoV-2 patients PLoS ONE (2020) 15, e0240012-e0240012. PubMed Europe PubMed DOI PMC EPMC
Amaral,A., Fernandes,C., Morazzo,S., Rebordao,M.R., Szostek-Mioduchowska,A., Lukasik,K., Gawronska-Kozak,B., Telo da Gama,L., Skarzynski,D.J. and Ferreira-Dias,G. The Inhibition of Cathepsin G on Endometrial Explants With Endometrosis in the Mare Front Vet Sci (2020) 7, 582211-582211. PubMed Europe PubMed DOI PMC EPMC
Gartner,F., Knippschild,U. and Burster,T. Application of an Activity-Based Probe to Determine Proteolytic Activity of Cell Surface Cathepsin G by Mass Cytometry Data Acquisition ACS Omega (2020) 5, 28233-28238. PubMed Europe PubMed DOI PMC EPMC I
Guerra,M., Halls,V.S., Schatterny,J., Hagner,M., Mall,M.A. and Schultz,C. Protease FRET Reporters Targeting Neutrophil Extracellular Traps J Am Chem Soc (2020) PubMed Europe PubMed DOI
Huang,S., Thomsson,K.A., Jin,C., Alweddi,S., Struglics,A., Rolfson,O., Bjorkman,L.I., Kalamajski,S., Schmidt,T.A., Jay,G.D., Krawetz,R., Karlsson,N.G. and Eisler,T. Cathepsin G degrades both glycosylated and unglycosylated regions of lubricin, a synovial mucin Sci Rep (2020) 10, 4215-4215. PubMed Europe PubMed DOI PMC EPMC
Morimoto-Kamata,R., Tsuji,D. and Yui,S. Cathepsin G-Induced Insulin-Like Growth Factor (IGF) Elevation in MCF-7 Medium Is Caused by Proteolysis of IGF Binding Protein (IGFBP)-2 but Not of IGF-1 Biol Pharm Bull (2020) 43, 1678-1686. PubMed Europe PubMed DOI
Sanchez Di Maggio,L., Tirloni,L., Uhl,M., Carmona,C., Logullo,C., Mulenga,A., da Silva,V.I., Jr. and Berasain,P. Serpins in Fasciola hepatica: insights into host-parasite interactions Int J Parasitol (2020) PubMed Europe PubMed DOI
Schroeder,R., Grzywa,R., Wirtz,C.R., Sienczyk,M. and Burster,T. Application of a novel FAM-conjugated activity-based probe to determine cathepsin G activity intracellularly Anal Biochem (2020) 588, 113488-113488. PubMed Europe PubMed DOI L
Sowinska,A., Rensing,M., Klevenvall,L., Neog,M., Lundback,P. and Harris,H.E. Cleavage of HMGB1 by Proteolytic Enzymes Associated with Inflammatory Conditions Front Immunol (2020) 11, 448262-448262. PubMed Europe PubMed DOI PMC EPMC
Voynow,J.A., Zheng,S. and Kummarapurugu,A.B. Glycosaminoglycans as Multifunctional Anti-Elastase and Anti-Inflammatory Drugs in Cystic Fibrosis Lung Disease Front Pharmacol (2020) 11, 1011-1011. PubMed Europe PubMed DOI PMC EPMC
Zamolodchikova,T.S., Tolpygo,S.M. and Svirshchevskaya,E.V. Cathepsin G - not only inflammation: the immune protease can regulate normal physiological processes Front Immunol (2020) 11, 411-411. PubMed Europe PubMed DOI PMC EPMC

2019

Aghdassi,A.A., John,D.S., Sendler,M., Storck,C., van den Brandt,C., Kruger,B., Weiss,F.U., Mayerle,J. and Lerch,M.M. Absence of the neutrophil serine protease cathepsin G decreases neutrophil granulocyte infiltration but does not change the severity of acute pancreatitis Sci Rep (2019) 9, 16774-16774. PubMed Europe PubMed DOI
Burgener,S.S., Leborgne,N.G.F., Snipas,S.J., Salvesen,G.S., Bird,P.I. and Benarafa,C. Cathepsin G inhibition by serpinb1 and serpinb6 prevents programmed necrosis in neutrophils and monocytes and reduces GSDMD-driven inflammation Cell Rep (2019) 27, 3646-3656. PubMed Europe PubMed DOI
Groborz,K., Kolt,S., Kasperkiewicz,P. and Drag,M. Internally quenched fluorogenic substrates with unnatural amino acids for cathepsin G investigation Biochimie (2019) 166, 103-111. PubMed Europe PubMed DOI A
Guerra,M., Frey,D., Hagner,M., Dittrich,S., Paulsen,M., Mall,M.A. and Schultz,C. Cathepsin G activity as a new marker for detecting airway inflammation by microscopy and flow cytometry ACS Cent Sci (2019) 5, 539-548. PubMed Europe PubMed DOI PMC EPMC
Guo,J., Tu,J., Hu,Y., Song,G. and Yin,Z. Cathepsin G cleaves and activates IL-36gamma and promotes the inflammation of psoriasis Drug Des Devel Ther (2019) 13, 581-588. PubMed Europe PubMed DOI PMC EPMC
Kish,D.D., Min,S., Dvorina,N., Baldwin WM 3rd, Stohlman,S.A. and Fairchild,R.L. Neutrophil cathepsin G regulates dendritic cell production of IL-12 during development of CD4 T cell responses to antigens in the skin J Immunol (2019) 202, 1045-1056. PubMed Europe PubMed DOI K
Krasavin,M.Y., Gureev,M.A., Garabadzhiu,A.V., Pashkin,A.Y., Zhukov,A.S., Khairutdinov,V.R., Samtsov,A.V. and Shvets,V.I. Inhibition of neutrophil elastase and cathepsin G as a new approach to the treatment of psoriasis: from fundamental biology to development of new target-specific drugs Dokl Biochem Biophys (2019) 487, 272-276. PubMed Europe PubMed DOI I
Kusumaningrum,N., Oh,J.H., Lee,D.H., Shin,C.Y., Jang,J.H., Kim,Y.K. and Chung,J.H. Topical treatment with a cathepsin G inhibitor, beta-keto-phosphonic acid, blocks ultraviolet irradiation-induced basement membrane damage in hairless mouse skin Photodermatol Photoimmunol Photomed (2019) 35, 148-156. PubMed Europe PubMed DOI I
Miller,S.A., Kolpakov,M.A., Guo,X., Du,B., Nguyen,Y., Wang,T., Powel,P., Dell'Italia,L.J. and Sabri,A. Intracardiac administration of neutrophil protease cathepsin G activates noncanonical inflammasome pathway and promotes inflammation and pathological remodeling in non-injured heart J Mol Cell Cardiol (2019) 134, 29-39. PubMed Europe PubMed DOI
Penczek,A. and Burster,T. Cell surface cathepsin G can be used as an additional marker to distinguish T cell subsets Biomed Rep (2019) 10, 245-249. PubMed Europe PubMed DOI PMC EPMC
Sionov,R.V., Fainsod-Levi,T., Zelter,T., Polyansky,L., Pham,C.T. and Granot,Z. Neutrophil cathepsin G and tumor cell RAGE facilitate neutrophil anti-tumor cytotoxicity Oncoimmunology (2019) 8, e1624129-e1624129. PubMed Europe PubMed DOI PMC EPMC

2018

Folco,E.J., Mawson,T.L., Vromman,A., Bernardes-Souza,B., Franck,G., Persson,O., Nakamura,M., Newton,G., Luscinskas,F.W. and Libby,P. Neutrophil extracellular traps induce endothelial cell activation and tissue factor production through interleukin-1alpha and cathepsin G Arterioscler Thromb Vasc Biol (2018) 38, 1901-1912. PubMed Europe PubMed DOI
Gudmann,N.S., Manon-Jensen,T., Sand,J.M.B., Diefenbach,C., Sun,S., Danielsen,A., Karsdal,M.A. and Leeming,D.J. Lung tissue destruction by proteinase 3 and cathepsin G mediated elastin degradation is elevated in chronic obstructive pulmonary disease Biochem Biophys Res Commun (2018) 503, 1284-1290. PubMed Europe PubMed DOI
Jun,H.K., Jung,Y.J., Ji,S., An,S.J. and Choi,B.K. Caspase-4 activation by a bacterial surface protein is mediated by cathepsin G in human gingival fibroblasts Cell Death Differ (2018) 25, 380-391. PubMed Europe PubMed DOI
Nguyen,M.T.N., Shema,G., Zahedi,R.P. and Verhelst,S.H.L. Protease specificity profiling in a pipet tip using "charge-synchronized" proteome-derived peptide libraries J Proteome Res (2018) 17, 1923-1933. PubMed Europe PubMed DOI P
Seif,K., Alidzanovic,L., Tischler,B., Ibrahim,N., Zagrapan,B., Rauscher,S., Salzmann,M., Hell,L., Mauracher,L.M., Budde,U., Schmid,J.A., Jilma,B., Pabinger,I., Assinger,A., Starlinger,P. and Brostjan,C. Neutrophil-mediated proteolysis of thrombospondin-1 promotes platelet adhesion and string formation Thromb Haemost (2018) 118, 2074-2085. PubMed Europe PubMed DOI
Thorpe,M., Fu,Z., Chahal,G., Akula,S., Kervinen,J., de Garavilla,L. and Hellman,L. Extended cleavage specificity of human neutrophil cathepsin G: a low activity protease with dual chymase and tryptase-type specificities PLoS ONE (2018) 13, e0195077-e0195077. PubMed Europe PubMed DOI P

2017

Benarafa,C. and Simon,H.U. Role of granule proteases in the life and death of neutrophils Biochem Biophys Res Commun (2017) 482, 473-481. PubMed Europe PubMed DOI V
Fu,Z., Thorpe,M., Alemayehu,R., Roy,A., Kervinen,J., de Garavilla,L., Abrink,M. and Hellman,L. Highly selective cleavage of cytokines and chemokines by the human mast cell chymase and neutrophil cathepsin G J Immunol (2017) 198, 1474-1483. PubMed Europe PubMed DOI P
Khan,M., Carmona,S., Sukhumalchandra,P., Roszik,J., Philips,A., Perakis,A.A., Kerros,C., Zhang,M., Qiao,N., John,L.S.S., Zope,M., Goldberg,J., Qazilbash,M., Jakher,H., Clise-Dwyer,K., Qiu,Y., Mittendorf,E.A., Molldrem,J.J., Kornblau,S.M. and Alatrash,G. Cathepsin G is expressed by acute lymphoblastic leukemia and is a potential immunotherapeutic target Front Immunol (2017) 8, 1975-1975. PubMed Europe PubMed DOI PMC EPMC T
Morimoto-Kamata,R. and Yui,S. Insulin-like growth factor-1 signaling is responsible for cathepsin G-induced aggregation of breast cancer MCF-7 cells Cancer Sci (2017) 108, 1574-1583. PubMed Europe PubMed DOI
Swedberg,J.E., Li,C.Y., de Veer,S.J., Wang,C.K. and Craik,D.J. Design of potent and selective cathepsin G inhibitors based on the sunflower trypsin inhibitor-1 scaffold J Med Chem (2017) 60, 658-667. PubMed Europe PubMed DOI P
Valayer,A., Brea,D., Lajoie,L., Avezard,L., Combes-Soia,L., Labas,V., Korkmaz,B., Thibault,G., Baranek,T. and Si-Tahar,M. Neutrophils can disarm NK cell response through cleavage of NKp46 J Leukoc Biol (2017) 101, 253-259. PubMed Europe PubMed DOI
Woo,S.M., Min,K.J., Seo,S.U., Kim,S., Park,J.W., Song,D.K., Lee,H.S., Kim,S.H. and Kwon,T.K. Up-regulation of 5-lipoxygenase by inhibition of cathepsin G enhances TRAIL-induced apoptosis through down-regulation of survivin Oncotarget (2017) 8, 106672-106684. PubMed Europe PubMed DOI PMC EPMC I

2016

Craciun,I., Fenner,A.M. and Kerns,R.J. N-Arylacyl O-sulfonated aminoglycosides as novel inhibitors of human neutrophil elastase, cathepsin G and proteinase 3 Glycobiology (2016) 26, 701-709. PubMed Europe PubMed DOI I
Eipper,S., Steiner,R., Lesner,A., Sienczyk,M., Palesch,D., Halatsch,M.E., Zaczynska,E., Heim,C., Hartmann,M.D., Zimecki,M., Wirtz,C.R. and Burster,T. Lactoferrin is an allosteric enhancer of the proteolytic activity of cathepsin G PLoS ONE (2016) 11, e0151509-e0151509. PubMed Europe PubMed DOI PMC EPMC
Giese,M., Turiello,N., Molenda,N., Palesch,D., Meid,A., Schroeder,R., Basilico,P., Benarafa,C., Halatsch,M.E., Zimecki,M., Westhoff,M.A., Wirtz,C.R. and Burster,T. Exogenous cathepsin G upregulates cell surface MHC class I molecules on immune and glioblastoma cells Oncotarget (2016) 7, 74602-74611. PubMed Europe PubMed DOI
Ortega-Gomez,A., Salvermoser,M., Rossaint,J., Pick,R., Brauner,J., Lemnitzer,P., Tilgner,J., de Jong,R.J., Megens,R.T., Jamasbi,J., Doring,Y., Pham,C.T., Scheiermann,C., Siess,W., Drechsler,M., Weber,C., Grommes,J., Zarbock,A., Walzog,B. and Soehnlein,O. Cathepsin G controls arterial but not venular myeloid cell recruitment Circulation (2016) 134, 1176-1188. PubMed Europe PubMed DOI
Palesch,D., Wagner,J., Meid,A., Molenda,N., Sienczyk,M., Burkhardt,J., Munch,J., Prokop,L., Stevanovic,S., Westhoff,M.A., Halatsch,M.E., Wirtz,C.R., Zimecki,M. and Burster,T. Cathepsin G-mediated proteolytic degradation of MHC class I molecules to facilitate immune detection of human glioblastoma cells Cancer Immunol Immunother (2016) 65, 283-291. PubMed Europe PubMed DOI
Penczek,A., Sienczyk,M., Wirtz,C.R. and Burster,T. Cell surface cathepsin G activity differs between human natural killer cell subsets Immunol Lett (2016) 179, 80-84. PubMed Europe PubMed DOI L

2015

Liu,X., Tian,Y., Meng,Z., Chen,Y., Ho,I.H., Choy,K.W., Lichtner,P., Wong,S.H., Yu,J., Gin,T., Wu,W.K., Cheng,C.H. and Chan,M.T. Up-regulation of cathepsin G in the development of chronic postsurgical pain: an experimental and clinical genetic study Anesthesiology (2015) 123, 838-850. PubMed Europe PubMed DOI M I
Loke,I., Packer,N.H. and Thaysen-Andersen,M. Complementary LC-MS/MS-based N-glycan, N-glycopeptide, and intact N-glycoprotein profiling reveals unconventional Asn71-glycosylation of human neutrophil cathepsin G Biomolecules (2015) 5, 1832-1854. PubMed Europe PubMed DOI
Mingli,Y., Zhuo,Z. and Jin,Z. The role of cathepsin G in the diagnosis and immunotherapy of acute myeloid leukemia J Leuk Lymphoma (2015) 24, 190-192. DOI V
Walter,K., Steinwede,K., Aly,S., Reinheckel,T., Bohling,J., Maus,U.A. and Ehlers,S. Cathepsin G in experimental tuberculosis: relevance for antibacterial protection and potential for immunotherapy J Immunol (2015) 195, 3325-3333. PubMed Europe PubMed DOI
Wang,J., Sukhova,G.K., Liu,J., Ozaki,K., Lesner,A., Libby,P., Kovanen,P.T. and Shi,G.P. Cathepsin G deficiency reduces periaortic calcium chloride injury-induced abdominal aortic aneurysms in mice J Vasc Surg (2015) 62, 1615-1624. PubMed Europe PubMed DOI K

2014

Brehm,A., Geraghty,P., Campos,M., Garcia-Arcos,I., Dabo,A.J., Gaffney,A., Eden,E., Jiang,X.C., D'Armiento,J. and Foronjy,R. Cathepsin G degradation of phospholipid transfer protein (PLTP) augments pulmonary inflammation FASEB J (2014) 28, 2318-2331. PubMed Europe PubMed DOI
Grzywa,R., Gorodkiewicz,E., Burchacka,E., Lesner,A., Laudanski,P., Lukaszewski,Z. and Sienczyk,M. Determination of cathepsin G in endometrial tissue using a surface plasmon resonance imaging biosensor with tailored phosphonic inhibitor Eur J Obstet Gynecol Reprod Biol (2014) 182, 38-42. PubMed Europe PubMed DOI A I
Grzywa,R., Burchacka,E., Lecka,M., Winiarski,L., Walczak,M., Lupicka-Slowik,A., Wysocka,M., Burster,T., Bobrek,K., Csencsits-Smith,K., Lesner,A. and Sienczyk,M. Synthesis of novel phosphonic-type activity-based probes for neutrophil serine proteases and their application in spleen lysates of different organisms Chembiochem (2014) 15, 2605-2612. PubMed Europe PubMed DOI I
Stapels,D.A., Ramyar,K.X., Bischoff,M., von Kockritz-Blickwede,M., Milder,F.J., Ruyken,M., Eisenbeis,J., McWhorter,W.J., Herrmann,M., Van Kessel,K.P., Geisbrecht,B.V. and Rooijakkers,S.H. Staphylococcus aureus secretes a unique class of neutrophil serine protease inhibitors Proc Natl Acad Sci U S A (2014) 111, 13187-13192. PubMed Europe PubMed DOI S
Wang,J., Sjoberg,S., Tang,T.T., Oorni,K., Wu,W., Liu,C., Secco,B., Tia,V., Sukhova,G.K., Fernandes,C., Lesner,A., Kovanen,P.T., Libby,P., Cheng,X. and Shi,G.P. Cathepsin G activity lowers plasma LDL and reduces atherosclerosis Biochim Biophys Acta (2014) 1842, 2174-2183. PubMed Europe PubMed DOI
Yui,S., Osawa,Y., Ichisugi,T. and Morimoto-Kamata,R. Neutrophil cathepsin G, but not elastase, induces aggregation of MCF-7 mammary carcinoma cells by a protease activity-dependent cell-oriented mechanism Mediators Inflamm (2014) 2014, 971409-971409. PubMed Europe PubMed DOI PMC EPMC

2013

Alatrash,G. Targeting cathepsin G in myeloid leukemia Oncoimmunology (2013) 2, e23442-e23442. PubMed Europe PubMed DOI PMC EPMC T
Baumann,M., Pham,C.T. and Benarafa,C. SerpinB1 is critical for neutrophil survival through cell-autonomous inhibition of cathepsin G Blood (2013) 121, 19-19. PubMed Europe PubMed DOI
De Freitas Caires,N., Legendre,B., Parmentier,E., Scherpereel,A., Tsicopoulos,A., Mathieu,D. and Lassalle,P. Identification of a 14kDa endocan fragment generated by cathepsin G, a novel circulating biomarker in patients with sepsis J Pharm Biomed Anal (2013) 78-79, 45-51. PubMed Europe PubMed DOI
Faraday,N., Schunke,K., Saleem,S., Fu,J., Wang,B., Zhang,J., Morrell,C. and Dore,S. Cathepsin G-dependent modulation of platelet thrombus formation in vivo by blood neutrophils PLoS ONE (2013) 8, e71447-e71447. PubMed Europe PubMed DOI PMC EPMC K I
Jin,W., Wu,K., Li,Y.Z., Yang,W.T., Zou,B., Zhang,F., Zhang,J. and Wang,K.K. AML1-ETO targets and suppresses cathepsin G, a serine protease, which is able to degrade AML1-ETO in t(8;21) acute myeloid leukemia Oncogene (2013) 32, 1978-1987. PubMed Europe PubMed DOI
Kosikowska,P. and Lesner,A. Inhibitors of cathepsin G: a patent review (2005 to present) Expert Opin Ther Pat (2013) 23, 1611-1624. PubMed Europe PubMed DOI V I
Rafatian,N., Karunakaran,D., Rayner,K.J., Leenen,F.H., Milne,R.W. and Whitman,S.C. Cathepsin G deficiency decreases complexity of atherosclerotic lesions in apolipoprotein E-deficient mice Am J Physiol Heart Circ Physiol (2013) 305, H1141-H1148. PubMed Europe PubMed DOI K

2012

Brea,D., Meurens,F., Dubois,A.V., Gaillard,J., Chevaleyre,C., Jourdan,M.L., Winter,N., Arbeille,B., Si-Tahar,M., Gauthier,F. and Attucci,S. The pig as a model for investigating the role of neutrophil serine proteases in human inflammatory lung diseases Biochem J (2012) 447, 363-370. PubMed Europe PubMed DOI
Dubois,A.V., Gauthier,A., Brea,D., Varaigne,F., Diot,P., Gauthier,F. and Attucci,S. Influence of DNA on the activities and inhibition of neutrophil serine proteases in cystic fibrosis sputum Am J Respir Cell Mol Biol (2012) 47, 80-86. PubMed Europe PubMed DOI
Gorodkiewicz,E., Sienczyk,M., Regulska,E., Grzywa,R., Pietrusewicz,E., Lesner,A. and Lukaszewski,Z. Surface plasmon resonance imaging biosensor for cathepsin G based on a potent inhibitor: development and applications Anal Biochem (2012) 423, 218-223. PubMed Europe PubMed DOI I
Govekar,R., Kawle,P., Thomas,R., Advani,S., Pv,S. and Zingde,S. Eryptotic phenotype in chronic myeloid leukemia: contribution of neutrophilic cathepsin G Anemia (2012) 2012, 659303-659303. PubMed Europe PubMed DOI PMC EPMC
Heinz,A., Jung,M.C., Jahreis,G., Rusciani,A., Duca,L., Debelle,L., Weiss,A.S., Neubert,R.H. and Schmelzer,C.E. The action of neutrophil serine proteases on elastin and its precursor Biochimie (2012) 94, 192-202. PubMed Europe PubMed DOI P
Korkmaz,B., Attucci,S., Epinette,C., Pitois,E., Jourdan,M.L., Juliano,L. and Gauthier,F. Measurement of neutrophil elastase, proteinase 3, and cathepsin G activities using intramolecularly quenched fluorogenic substrates Methods Mol Biol (2012) 844, 125-138. PubMed Europe PubMed DOI A
Lefrancais,E., Roga,S., Gautier,V., Gonzalez-de-Peredo,A., Monsarrat,B., Girard,J.P. and Cayrol,C. IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G Proc Natl Acad Sci U S A (2012) 109, 1673-1678. PubMed Europe PubMed DOI PMC EPMC P
Madsen,J.L., Andersen,T.L., Santamaria,S., Nagase,H., Enghild,J.J. and Skrydstrup,T. Synthesis and evaluation of silanediols as highly selective uncompetitive inhibitors of human neutrophil elastase J Med Chem (2012) 55, 7900-7908. PubMed Europe PubMed DOI I
Morimoto-Kamata,R., Mizoguchi,S., Ichisugi,T. and Yui,S. Cathepsin G induces cell aggregation of human breast cancer MCF-7 cells via a 2-step mechanism: catalytic site-independent binding to the cell surface and enzymatic activity-dependent induction of the cell aggregation Mediators Inflamm (2012) 2012, 456462-456462. PubMed Europe PubMed DOI PMC EPMC
Salvesen,G.S. Cathepsin G [ISSN:978-0-12-407742-3] (2012) 3, 2661-2666. DOI
Schmelzer,C.E., Jung,M.C., Wohlrab,J., Neubert,R.H. and Heinz,A. Does human leukocyte elastase degrade intact skin elastin? FEBS J (2012) 279, 4191-4200. PubMed Europe PubMed DOI
Son,E.D., Shim,J.H., Choi,H., Kim,H., Lim,K.M., Chung,J.H., Byun,S.Y. and Lee,T.R. Cathepsin G inhibitor prevents ultraviolet B- induced photoaging in hairless mice via inhibition of fibronectin fragmentation Dermatology (2012) 224, 352-360. PubMed Europe PubMed DOI I
Woloszynek,J.C., Hu,Y. and Pham,C.T. Cathepsin G-regulated release of formyl peptide receptor agonists modulate neutrophil effector functions J Biol Chem (2012) 287, 34101-34109. PubMed Europe PubMed DOI
Wysocka,M., Lesner,A., Gruba,N., Korkmaz,B., Gauthier,F., Kitamatsu,M., Legowska,A. and Rolka,K. Three wavelength substrate system of neutrophil serine proteinases Anal Chem (2012) 84, 7241-7248. PubMed Europe PubMed DOI A
Wysocka,M., Lesner,A., Popow,J., Legowska,M. and Rolka,K. Pegylated fluorescent peptides as substrates of proteolytic enzymes Protein Pept Lett (2012) 19, 1237-1244. PubMed Europe PubMed A P
Zou,F., Schmon,M., Sienczyk,M., Grzywa,R., Palesch,D., Boehm,B.O., Sun,Z.L., Watts,C., Schirmbeck,R. and Burster,T. Application of a novel highly sensitive activity-based probe for detection of cathepsin G Anal Biochem (2012) 421, 667-672. PubMed Europe PubMed DOI A

2011

Danelishvili,L., Everman,J.L., McNamara,M.J. and Bermudez,L.E. Inhibition of the plasma-membrane-associated serine protease cathepsin G by Mycobacterium tuberculosis Rv3364c suppresses caspase-1 and pyroptosis in macrophages Front Microbiol (2011) 2, 281-281. PubMed Europe PubMed DOI PMC EPMC
Gorodkiewicz,E., Regulska,E. and Wojtulewski,K. Development of an SPR imaging biosensor for determination of cathepsin G in saliva and white blood cells Mikrochim Acta (2011) 173, 407-413. PubMed Europe PubMed DOI A I
Hahn,I., Klaus,A., Janze,A.K., Steinwede,K., Ding,N., Bohling,J., Brumshagen,C., Serrano,H., Gauthier,F., Paton,J.C., Welte,T. and Maus,U.A. Cathepsin G and neutrophil elastase play critical and nonredundant roles in lung-protective immunity against Streptococcus pneumoniae in mice Infect Immun (2011) 79, 4893-4901. PubMed Europe PubMed DOI
Kessenbrock,K., Dau,T. and Jenne,D.E. Tailor-made inflammation: how neutrophil serine proteases modulate the inflammatory response J Mol Med (Berl) (2011) 89, 23-28. PubMed Europe PubMed DOI
Korkmaz,B., Jegot,G., Lau,L.C., Thorpe,M., Pitois,E., Juliano,L., Walls,A.F., Hellman,L. and Gauthier,F. Discriminating between the activities of human cathepsin G and chymase using fluorogenic substrates FEBS J (2011) 278, 2635-2646. PubMed Europe PubMed DOI A P
Palesch,D., Sienczyk,M., Oleksyszyn,J., Reich,M., Wieczerzak,E., Boehm,B.O. and Burster,T. Was the serine protease cathepsin G discovered by S. G. Hedin in 1903 in bovine spleen? Acta Biochim Pol (2011) 58, 39-44. PubMed Europe PubMed
Tsuchiya,Y., Okada,G., Kobayashi,S., Chikuma,T. and Hojo,H. 4-hydroxy-2-nonenal-modified glyceraldehyde-3-phosphate dehydrogenase is degraded by cathepsin G in rat neutrophils Oxid Med Cell Longev (2011) 2011, 213686-213686. PubMed Europe PubMed DOI

2010

Burster,T., Macmillan,H., Hou,T., Boehm,B.O. and Mellins,E.D. Cathepsin G: roles in antigen presentation and beyond Mol Immunol (2010) 47, 658-665. PubMed Europe PubMed DOI
Burster,T., Macmillan,H., Hou,T., Schilling,J., Truong,P., Boehm,B.O., Zou,F., Lau,K., Strohman,M., Schaffert,S., Busch,R. and Mellins,E.D. Masking of a cathepsin G cleavage site in vivo contributes to the proteolytic resistance of major histocompatibility complex class II molecules Immunology (2010) 130, 436-446. PubMed Europe PubMed DOI
Farberman,M.M., Akers,K.T., Malone,J.P., Erdman-Gilmore,P., Townsend,R.R. and Ferkol,T. Airway proteins involved in bacterial clearance susceptible to cathepsin G proteolysis Eur Respir J (2010) 35, 410-417. PubMed Europe PubMed DOI
Korkmaz,B., Horwitz,M.S., Jenne,D.E. and Gauthier,F. Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases Pharmacol Rev (2010) 62, 726-759. PubMed Europe PubMed DOI V T
Legowska,A., Debowski,D., Lesner,A., Wysocka,M. and Rolka,K. Selection of peptomeric inhibitors of bovine alpha-chymotrypsin and cathepsin G based on trypsin inhibitor SFTI-1 using a combinatorial chemistry approach Mol Divers (2010) 14, 51-58. PubMed Europe PubMed DOI I
Perrin,J., Lecompte,T., Tournier,A., Morlon,L., Marchand-Arvier,M. and Vigneron,C. In vitro effects of human neutrophil cathepsin G on thrombin generation: both acceleration and decreased potential Thromb Haemost (2010) 104, 514-522. PubMed Europe PubMed DOI
Raymond,W.W., Trivedi,N.N., Makarova,A., Ray,M., Craik,C.S. and Caughey,G.H. How immune peptidases change specificity: cathepsin G gained tryptic function but lost efficiency during primate evolution J Immunol (2010) 185, 5360-5368. PubMed Europe PubMed DOI P

2009

Kalupov,T., Brillard-Bourdet,M., Dade,S., Serrano,H., Wartelle,J., Guyot,N., Juliano,L., Moreau,T., Belaaouaj,A. and Gauthier,F. Structural characterization of mouse neutrophil serine proteases and identification of their substrate specificities: relevance to mouse models of human inflammatory diseases J Biol Chem (2009) 284, 34084-34091. PubMed Europe PubMed DOI P
Kudo,T., Kigoshi,H., Hagiwara,T., Takino,T., Yamazaki,M. and Yui,S. Cathepsin G, a neutrophil protease, induces compact cell-cell adhesion in MCF-7 human breast cancer cells Mediators Inflamm (2009) 2009, 850940-850940. PubMed Europe PubMed DOI PMC EPMC
Legowska,A., Debowski,D., Lesner,A., Wysocka,M. and Rolka,K. Introduction of non-natural amino acid residues into the substrate-specific P1 position of trypsin inhibitor SFTI-1 yields potent chymotrypsin and cathepsin G inhibitors Bioorg Med Chem (2009) 17, 3302-3307. PubMed Europe PubMed DOI
Lesner,A., Wysocka,M., Solek,M., Legowska,A. and Rolka,K. Low-molecular-weight aldehyde inhibitors of cathepsin G Protein Pept Lett (2009) 16, 408-410. PubMed Europe PubMed DOI I
Raife,T.J., Cao,W., Atkinson,B.S., Bedell,B., Montgomery,R.R., Lentz,S.R., Johnson,G.F. and Zheng,X.L. Leukocyte proteases cleave von Willebrand factor at or near the ADAMTS13 cleavage site Blood (2009) 114, 1666-1674. PubMed Europe PubMed DOI PMC EPMC P
Reich,M., Lesner,A., Legowska,A., Sienczyk,M., Oleksyszyn,J., Boehm,B.O. and Burster,T. Application of specific cell permeable cathepsin G inhibitors resulted in reduced antigen processing in primary dendritic cells Mol Immunol (2009) 46, 2994-2999. PubMed Europe PubMed DOI I
Son,E.D., Kim,H., Choi,H., Lee,S.H., Lee,J.Y., Kim,S., Closs,B., Lee,S., Chung,J.H. and Hwang,J.S. Cathepsin G increases MMP expression in normal human fibroblasts through fibronectin fragmentation, and induces the conversion of proMMP-1 to active MMP-1 J Dermatol Sci (2009) 53, 150-152. PubMed Europe PubMed DOI
Stoeckle,C., Sommandas,V., Adamopoulou,E., Belisle,K., Schiekofer,S., Melms,A., Weber,E., Driessen,C., Boehm,B.O., Tolosa,E. and Burster,T. Cathepsin G is differentially expressed in primary human antigen-presenting cells Cell Immunol (2009) 255, 41-45. PubMed Europe PubMed DOI
Tausch,L., Henkel,A., Siemoneit,U., Poeckel,D., Kather,N., Franke,L., Hofmann,B., Schneider,G., Angioni,C., Geisslinger,G., Skarke,C., Holtmeier,W., Beckhaus,T., Karas,M., Jauch,J. and Werz,O. Identification of human cathepsin G as a functional target of boswellic acids from the anti-inflammatory remedy frankincense J Immunol (2009) 183, 3433-3442. PubMed Europe PubMed DOI I
Wilson,T.J., Nannuru,K.C. and Singh,R.K. Cathepsin G recruits osteoclast precursors via proteolytic activation of protease-activated receptor-1 Cancer Res (2009) 69, 3188-3195. PubMed Europe PubMed DOI T
Wilson,T.J., Nannuru,K.C. and Singh,R.K. Cathepsin G-mediated activation of pro-matrix metalloproteinase 9 at the tumor-bone interface promotes transforming growth factor-beta signaling and bone destruction Mol Cancer Res (2009) 7, 1224-1233. PubMed Europe PubMed DOI

2008

Gale,A.J. and Rozenshteyn,D. Cathepsin G, a leukocyte protease, activates coagulation factor VIII Thromb Haemost (2008) 99, 44-51. PubMed Europe PubMed DOI
Gatto,B., Vianini,E., Lucatello,L., Sissi,C., Moltrasio,D., Pescador,R., Porta,R. and Palumbo,M. Effective DNA inhibitors of cathepsin G by in vitro selection Int J Mol Sci (2008) 9, 1008-1023. PubMed Europe PubMed DOI PMC EPMC
Korkmaz,B., Moreau,T. and Gauthier,F. Neutrophil elastase, proteinase 3 and cathepsin G: physicochemical properties, activity and physiopathological functions Biochimie (2008) 90, 227-242. PubMed Europe PubMed DOI V
Lesner,A., Wysocka,M., Guzow,K., Wiczk,W., Legowska,A. and Rolka,K. Development of sensitive cathepsin G fluorogenic substrate using combinatorial chemistry methods Anal Biochem (2008) 375, 306-312. PubMed Europe PubMed DOI A P
Mambole,A., Baruch,D., Nusbaum,P., Bigot,S., Suzuki,M., Lesavre,P., Fukuda,M. and Halbwachs-Mecarelli,L. The cleavage of neutrophil leukosialin (CD43) by cathepsin G releases its extracellular domain and triggers its intramembrane proteolysis by presenilin/gamma-secretase J Biol Chem (2008) 283, 23627-23635. PubMed Europe PubMed DOI PMC EPMC
Pham,C.T. Neutrophil serine proteases fine-tune the inflammatory response Int J Biochem Cell Biol (2008) 40, 1317-1333. PubMed Europe PubMed DOI PMC EPMC
Rafiq,K., Hanscom,M., Valerie,K., Steinberg,S.F. and Sabri,A. Novel mode for neutrophil protease cathepsin G-mediated signaling: membrane shedding of epidermal growth factor is required for cardiomyocyte anoikis Circ Res (2008) 102, 32-41. PubMed Europe PubMed DOI
Sienczyk,M., Lesner,A., Wysocka,M., Legowska,A., Pietrusewicz,E., Rolka,K. and Oleksyszyn,J. New potent cathepsin G phosphonate inhibitors Bioorg Med Chem (2008) 16, 8863-8867. PubMed Europe PubMed DOI I

2007

Burster,T., Beck,A., Poeschel,S., Oren,A., Baechle,D., Reich,M., Roetzschke,O., Falk,K., Boehm,B.O., Youssef,S., Kalbacher,H., Overkleeft,H., Tolosa,E. and Driessen,C. Interferon-gamma regulates cathepsin G activity in microglia-derived lysosomes and controls the proteolytic processing of myelin basic protein in vitro Immunology (2007) 121, 82-93. PubMed Europe PubMed DOI PMC EPMC
Campbell,E.J. and Owen,C.A. The sulfate groups of chondroitin sulfate- and heparan sulfate-containing proteoglycans in neutrophil plasma membranes are novel binding sites for human leukocyte elastase and cathepsin G J Biol Chem (2007) 282, 14645-14654. PubMed Europe PubMed DOI
Jahanyar,J., Youker,K.A., Loebe,M., Assad-Kottner,C., Koerner,M.M., Torre-Amione,G. and Noon,G.P. Mast cell-derived cathepsin G: a possible role in the adverse remodeling of the failing human heart J Surg Res (2007) 140, 199-203. PubMed Europe PubMed DOI
Miyata,J., Tani,K., Sato,K., Otsuka,S., Urata,T., Lkhagvaa,B., Furukawa,C., Sano,N. and Sone,S. Cathepsin G: the significance in rheumatoid arthritis as a monocyte chemoattractant Rheumatol Int (2007) 27, 375-382. PubMed Europe PubMed DOI
Ramos,H.L., O'Shea,J.J. and Watford,W.T. STAT5 isoforms: controversies and clarifications Biochem J (2007) 404, e1-e2. PubMed Europe PubMed DOI PMC EPMC
Schuster,B., Hendry,L., Byers,H., Lynham,S.F., Ward,M.A. and John,S. Purification and identification of the STAT5 protease in myeloid cells Biochem J (2007) 404, 81-87. PubMed Europe PubMed DOI PMC EPMC
Sedor,J., Hogue,L., Akers,K., Boslaugh,S., Schreiber,J. and Ferkol,T. Cathepsin-G interferes with clearance of Pseudomonas aeruginosa from mouse lungs Pediatr Res (2007) 61, 26-31. PubMed Europe PubMed DOI
Shimoda,N., Fukazawa,N., Nonomura,K. and Fairchild,R.L. Cathepsin G is required for sustained inflammation and tissue injury after reperfusion of ischemic kidneys Am J Pathol (2007) 170, 930-940. PubMed Europe PubMed DOI PMC EPMC T
Wysocka,M., Legowska,A., Bulak,E., Jaskiewicz,A., Miecznikowska,H., Lesner,A. and Rolka,K. New chromogenic substrates of human neutrophil cathepsin G containing non-natural aromatic amino acid residues in position P(1) selected by combinatorial chemistry methods Mol Divers (2007) 11, 93-99. PubMed Europe PubMed DOI A P

2006

Lim,J.K., Lu,W., Hartley,O. and DeVico,A.L. N-terminal proteolytic processing by cathepsin G converts RANTES/CCL5 and related analogs into a truncated 4-68 variant J Leukoc Biol (2006) 80, 1395-1404. PubMed Europe PubMed DOI P
Pham,C.T. Neutrophil serine proteases: specific regulators of inflammation Nat Rev Immunol (2006) 6, 541-550. PubMed Europe PubMed DOI V

2005

[YEAR:28-2-2005]de Garavilla,L., Greco,M.N., Sukumar,N., Chen,Z.W., Pineda,A.O., Mathews,F.S., Di Cera,E., Giardino,E.C., Wells,G.I., Haertlein,B.J., Kauffman,J.A., Corcoran,T.W., Derian,C.K., Eckardt,A.J., Damiano,B.P., Andrade-Gordon,P. and Maryanoff,B.E. A novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase: molecular mechanisms and anti-inflammatory activity in vivo J Biol Chem (28-2-2005) 280, 18001-18007. PubMed Europe PubMed DOI I
[YEAR:11-7-2005]Lennartsson,A., Garwicz,D., Lindmark,A. and Gullberg,U. The proximal promoter of the human cathepsin G gene conferring myeloid-specific expression includes C/EBP, c-myb and PU.1 binding sites Gene (11-7-2005) 356, 193-202. PubMed Europe PubMed DOI
Raptis,S.Z., Shapiro,S.D., Simmons,P.M., Cheng,A.M. and Pham,C.T. Serine protease cathepsin G regulates adhesion-dependent neutrophil effector functions by modulating integrin clustering Immunity (2005) 22, 679-691. PubMed Europe PubMed DOI
[YEAR:22-2-2005]Ryu,O.H., Choi,S.J., Firatli,E., Choi,S.W., Hart,P.S., Shen,R.F., Wang,G., Wu,W.W. and Hart,T.C. Proteolysis of macrophage inflammatory protein-1alpha isoforms LD78beta and LD78alpha by neutrophil-derived serine proteases J Biol Chem (22-2-2005) 280, 17415-17421. PubMed Europe PubMed DOI P
[YEAR:20-6-2005]Shao,B., Belaaouaj,A., Verlinde,C.L., Fu,X. and Heinecke,J.W. Methionine sulfoxide and proteolytic cleavage contribute to the inactivation of cathepsin G by hypochlorous acid: an oxidative mechanism for regulation of serine proteinases by myeloperoxidase J Biol Chem (20-6-2005) 280, 29311-29321. PubMed Europe PubMed DOI
[YEAR:1-7-2005]Wittamer,V., Bondue,B., Guillabert,A., Vassart,G., Parmentier,M. and Communi,D. Neutrophil-mediated maturation of chemerin: a link between innate and adaptive immunity J Immunol (1-7-2005) 175, 487-493. PubMed Europe PubMed

2004

[YEAR:1-1-2004]Beaufort,N., Leduc,D., Rousselle,J.C., Magdolen,V., Luther,T., Namane,A., Chignard,M. and Pidard,D. Proteolytic regulation of the urokinase receptor/CD87 on monocytic cells by neutrophil elastase and cathepsin G J Immunol (1-1-2004) 172, 540-549. PubMed Europe PubMed
[YEAR:1-5-2004]Burster,T., Beck,A., Tolosa,E., Marin-Esteban,V., Rotzschke,O., Falk,K., Lautwein,A., Reich,M., Brandenburg,J., Schwarz,G., Wiendl,H., Melms,A., Lehmann,R., Stevanovic,S., Kalbacher,H. and Driessen,C. Cathepsin G, and not the asparagine-specific endoprotease, controls the processing of myelin basic protein in lysosomes from human B lymphocytes J Immunol (1-5-2004) 172, 5495-5503. PubMed Europe PubMed
Hendry,L. and John,S. Regulation of STAT signalling by proteolytic processing Eur J Biochem (2004) 271, 4613-4620. PubMed Europe PubMed DOI
[YEAR:1-1-2004]Lopez-Boado,Y.S., Espinola,M., Bahr,S. and Belaaouaj,A. Neutrophil serine proteinases cleave bacterial flagellin, abrogating its host response-inducing activity J Immunol (1-1-2004) 172, 509-515. PubMed Europe PubMed
Ottonello,L., Epstein,A.L., Mancini,M., Dapino,P. and Dallegri,F. Monoclonal LYM-1 antibody-dependent cytolysis by human neutrophils exposed to GM-CSF: auto-regulation of target cell attack by cathepsin G J Leukoc Biol (2004) 75, 99-105. PubMed Europe PubMed DOI
Rivera-Marrero,C.A., Stewart,J., Shafer,W.M. and Roman,J. The down-regulation of cathepsin G in THP-1 monocytes after infection with Mycobacterium tuberculosis is associated with increased intracellular survival of bacilli Infect Immun (2004) 72, 5712-5721. PubMed Europe PubMed DOI PMC EPMC
Salvesen,G.S. Cathepsin G [ISSN:0-12-079610-4] (2004) 2, 1524-1526. V
Tralau,T., Meyer-Hoffert,U., Schroder,J.M. and Wiedow,O. Human leukocyte elastase and cathepsin G are specific inhibitors of C5a-dependent neutrophil enzyme release and chemotaxis Exp Dermatol (2004) 13, 316-325. PubMed Europe PubMed DOI

2003

[YEAR:18-4-2003]Hermant,B., Bibert,S., Concord,E., Dublet,B., Weidenhaupt,M., Vernet,T. and Gulino-Debrac,D. Identification of proteases involved in the proteolysis of vascular endothelium cadherin during neutrophil transmigration J Biol Chem (18-4-2003) 278, 14002-14012. PubMed Europe PubMed DOI
[YEAR:27-2-2003]Ledoux,D., Merciris,D., Barritault,D. and Caruelle,J.P. Heparin-like dextran derivatives as well as glycosaminoglycans inhibit the enzymatic activity of human cathepsin G FEBS Lett (27-2-2003) 537, 23-29. PubMed Europe PubMed DOI
[YEAR:27-6-2003]Sabri,A., Alcott,S.G., Elouardighi,H., Pak,E., Derian,C., Andrade-Gordon,P., Kinnally,K. and Steinberg,S.F. Neutrophil cathepsin G promotes detachment-induced cardiomyocyte apoptosis via a protease-activated receptor-independent mechanism J Biol Chem (27-6-2003) 278, 23944-23954. PubMed Europe PubMed DOI

2002

[YEAR:15-9-2002]Attucci,S., Korkmaz,B., Juliano,L., Hazouard,E., Girardin,C., Brillard-Bourdet,M., Rehault,S., Anthonioz,P. and Gauthier,F. Measurement of free and membrane-bound cathepsin G in human neutrophils using new sensitive fluorogenic substrates Biochem J (15-9-2002) 366, 965-970. PubMed Europe PubMed DOI PMC EPMC
Considine,T., Geary,S., Kelly,A.L. and McSweeney,P.L.H. Proteolytic specificity of cathepsin G on bovine alphas1- and beta-caseins Food Chem (2002) 76, 59-67. DOI P
[YEAR:15-6-2002]Gutschow,M., Kuerschner,L., Pietsch,M., Ambrozak,A., Neumann,U., Gunther,R. and Hofmann,H.J. Inhibition of cathepsin G by 2-amino-3,1-benzoxazin-4-ones: kinetic investigations and docking studies Arch Biochem Biophys (15-6-2002) 402, 180-191. PubMed Europe PubMed DOI
[YEAR:1-1-2002]Ramaha,A. and Patston,P.A. Release and degradation of angiotensin I and angiotensin II from angiotensinogen by neutrophil serine proteinases Arch Biochem Biophys (1-1-2002) 397, 77-83. PubMed Europe PubMed DOI

2001

[YEAR:9-7-2001]Aoyama,Y., Uenaka,M., Konoike,T., Hayasaki-Kajiwara,Y., Naya,N. and Nakajima,M. Inhibition of serine proteases: activity of 1,3-diazetidine-2,4-diones Bioorg Med Chem Lett (9-7-2001) 11, 1691-1694. PubMed Europe PubMed DOI I
[YEAR:24-8-2001]Bhojak,T.J., DeKosky,S.T., Ganguli,M. and Kamboh,M.Y. Genetic polymorphism in the cathepsin G gene and the risk of Alzheimer's disease Neurosci Lett (24-8-2001) 309, 138-140. PubMed Europe PubMed DOI M
Cumashi,A., Ansuini,H., Celli,N., De Blasi,A., O'Brien,P.J., Brass,L.F. and Molino,M. Neutrophil proteases can inactivate human PAR3 and abolish the co-receptor function of PAR3 on murine platelets Thromb Haemost (2001) 85, 533-538. PubMed Europe PubMed
Delgado,M.B., Clark-Lewis,I., Loetscher,P., Langen,H., Thelen,M., Baggiolini,M. and Wolf,M. Rapid inactivation of stromal cell-derived factor-1 by cathepsin G associated with lymphocytes Eur J Immunol (2001) 31, 699-707. PubMed Europe PubMed DOI
Herrmann,S.M., Funke-Kaiser,H., Schmidt-Petersen,K., Nicaud,V., Gautier-Bertrand,M., Evans,A., Kee,F., Arveiler,D., Morrison,C., Orzechowski,H.D., Elbaz,A., Amarenco,P., Cambien,F. and Paul,M. Characterization of polymorphic structure of cathepsin G gene: role in cardiovascular and cerebrovascular diseases Arterioscler Thromb Vasc Biol (2001) 21, 1538-1543. PubMed Europe PubMed M
[YEAR:13-4-2001]Tani,K., Murphy,W.J., Chertov,O., Oppenheim,J.J. and Wang,J.M. The neutrophil granule protein cathepsin G activates murine T lymphocytes and upregulates antigen-specific Ig production in mice Biochem Biophys Res Commun (13-4-2001) 282, 971-976. PubMed Europe PubMed DOI
[YEAR:15-2-2001]Xia,Z., Salzler,R.R., Kunz,D.P., Baer,M.R., Kazim,L., Baumann,H. and Wetzler,M. A novel serine-dependent proteolytic activity is responsible for truncated signal transducer and activator of transcription proteins in acute myeloid leukemia blasts Cancer Res (15-2-2001) 61, 1747-1753. PubMed Europe PubMed

2000

Moriuchi,H., Moriuchi,M. and Fauci,A.S. Cathepsin G, a neutrophil-derived serine protease, increases susceptibility of macrophages to acute human immunodeficiency virus type 1 infection J Virol (2000) 74, 6849-6855. PubMed Europe PubMed DOI PMC EPMC
Sambrano,G.R., Huang,W., Faruqi,T., Mahrus,S., Craik,C. and Coughlin,S.R. Cathepsin G activates protease-activated receptor-4 in human platelets J Biol Chem (2000) 275, 6819-6823. PubMed Europe PubMed DOI
Tkalcevic,J., Novelli,M., Phylactides,M., Iredale,J.P., Segal,A.W. and Roes,J. Impaired immunity and enhanced resistance to endotoxin in the absence of neutrophil elastase and cathepsin G Immunity (2000) 12, 201-210. PubMed Europe PubMed K

1999

[YEAR:17-9-1999]Lee,C., Piazza,F., Brutsaert,S., Valens,J., Strehlow,I., Jarosinski,M., Saris,C. and Schindler,C. Characterization of the Stat5 protease J Biol Chem (17-9-1999) 274, 26767-26775. PubMed Europe PubMed DOI P
[YEAR:15-12-1999]MacIvor,D.M., Shapiro,S.D., Pham,C.T., Belaaouaj,A., Abraham,S.N. and Ley,T.J. Normal neutrophil function in cathepsin G-deficient mice Blood (15-12-1999) 94, 4282-4293. PubMed Europe PubMed K
[YEAR:14-5-1999]Rehault,S., Brillard-Bourdet,M., Juliano,M.A., Juliano,L., Gauthier,F. and Moreau,T. New, sensitive fluorogenic substrates for human cathepsin G based on the sequence of serpin-reactive site loops J Biol Chem (14-5-1999) 274, 13810-13817. PubMed Europe PubMed DOI
[YEAR:15-3-1999]Scott,F.L., Hirst,C.E., Sun,J., Bird,C.H., Bottomley,S.P. and Bird,P.I. The intracellular serpin proteinase inhibitor 6 is expressed in monocytes and granulocytes and is a potent inhibitor of the azurophilic granule protease, cathepsin G Blood (15-3-1999) 93, 2089-2097. PubMed Europe PubMed

1998

Ilton,M.K., Taylor,M.L., Misso,N.L., Thompson,P.J. and Hung,J. Neutrophil cathepsin G modulates platelet P-selectin expression and inhibits P-selectin-mediated platelet-neutrophil adhesion Clin Sci (Lond) (1998) 94, 437-445. PubMed Europe PubMed
[YEAR:15-3-1998]Meyer,J., Jucker,M., Ostertag,W. and Stocking,C. Carboxyl-truncated STAT5beta is generated by a nucleus-associated serine protease in early hematopoietic progenitors Blood (15-3-1998) 91, 1901-1908. PubMed Europe PubMed
[YEAR:28-7-1998]Polanowska,J., Krokoszynska,I., Czapinska,H., Watorek,W., Dadlez,M. and Otlewski,J. Specificity of human cathepsin G Biochim Biophys Acta (28-7-1998) 1386, 189-198. PubMed Europe PubMed DOI

1997

Aveskogh,M., Lutzelschwab,C., Huang,M.R. and Hellman,L. Characterization of cDNA clones encoding mouse proteinase 3 (myeloblastine) and cathepsin G Immunogenetics (1997) 46, 181-191. PubMed Europe PubMed DOI

1996

Groutas,W.C., Epp,J.B., Venkataraman,R., Kuang,R., Truong,T.M., McClenahan,J.J. and Prakash,O. Design, synthesis, and in vitro inhibitory activity toward human leukocyte elastase, cathepsin G, and proteinase 3 of saccharin-derived sulfones and congeners Bioorg Med Chem (1996) 4, 1393-1400. PubMed Europe PubMed DOI I
Hof,P., Mayr,I., Huber,R., Korzus,E., Potempa,J., Travis,J., Powers,J.C. and Bode,W. The 1.8 A crystal structure of human cathepsin G in complex with Suc-Val-Pro-Phe(P)-(OPh)(2): a Janus-faced proteinase with two opposite specificities EMBO J (1996) 15, 5481-5491. PubMed Europe PubMed PMC EPMC S I
[YEAR:22-3-1996]Kordula,T., Ripperger,J., Morella,K.M., Travis,J. and Baumann,H. Two separate signal transducer and activator of transcription proteins regulate transcription of the serine proteinase inhibitor-3 gene in hepatic cells J Biol Chem (22-3-1996) 271, 6752-6757. PubMed Europe PubMed DOI

1995

[YEAR:20-1-1995]Allen,D.H. and Tracy,P.B. Human coagulation factor V is activated to the functional cofactor by elastase and cathepsin G expressed at the monocyte surface J Biol Chem (20-1-1995) 270, 1408-1415. PubMed Europe PubMed DOI
Cavarra,E., Santucci,A. and Lungarella,G. Purification and N-terminal amino-acid sequence analysis of rabbit neutrophil cathepsin G Biol Chem Hoppe Seyler (1995) 376, 371-377. PubMed Europe PubMed
Garwicz,D., Lindmark,A. and Gullberg,U. Human cathepsin G lacking functional glycosylation site is proteolytically processed and targeted for storage in granules after transfection to the rat basophilic/mast cell line RBL or the murine myeloid cell line 32D J Biol Chem (1995) 270, 28413-28418. PubMed Europe PubMed DOI
Groutas,W.C., Brubaker,M.J., Chong,L.S., Venkataraman,R., Huang,H., Epp,J.B., Kuang,R. and Hoidal,J.R. Design, synthesis and biological evaluation of succinimide derivatives as potential mechanism-based inhibitors of human leukocyte elastase, cathepsin G and proteinase 3 Bioorg Med Chem (1995) 3, 375-381. PubMed Europe PubMed DOI I

1994

[YEAR:15-10-1994]Pidard,D., Renesto,P., Berndt,M.C., Rabhi,S., Clemetson,K.J. and Chignard,M. Neutrophil proteinase cathepsin G is proteolytically active on the human platelet glycoprotein Ib-IX receptor: characterization of the cleavage sites within the glycoprotein Ib alpha subunit Biochem J (15-10-1994) 303, 489-498. PubMed Europe PubMed PMC EPMC

1993

[YEAR:1-9-1993]Anderssen,T., Halvorsen,H., Bajaj,S.P. and Osterud,B. Human leukocyte elastase and cathepsin G inactivate factor VII by limited proteolysis Thromb Haemost (1-9-1993) 70, 414-417. PubMed Europe PubMed
Heusel,J.W., Scarpati,E.M., Jenkins,N.A., Gilbert,D.J., Copeland,N.G., Shapiro,S.D. and Ley,T.J. Molecular cloning, chromosomal location, and tissue-specific expression of the murine cathepsin G gene Blood (1993) 81, 1614-1623. PubMed Europe PubMed
Ludecke,B., Poller,W., Olek,K. and Bartholome,K. Sequence variant of the human cathepsin G gene Hum Genet (1993) 91, 83-84. PubMed Europe PubMed M

1992

Groutas,W.C., Brubaker,M.J., Venkataraman,R., Epp,J.B., Stanga,M.A. and McClenahan,J.J. Inhibitors of human neutrophil cathepsin G: structural and biochemical studies Arch Biochem Biophys (1992) 294, 144-146. PubMed Europe PubMed DOI I
Nakamura,N., Tsuru,A., Hirayoshi,K. and Nagata,K. Purification and characterization of a vimentin-specific protease in mouse myeloid leukemia cells. Regulation during differentiation and identity with cathepsin G Eur J Biochem (1992) 205, 947-954. PubMed Europe PubMed

1991

Abrahamson,M., Buttle,D.J., Mason,R.W., Hansson,H., Grubb,A., Lilja,H. and Ohlsson,K. Regulation of cystatin C activity by serine proteinases Biomed Biochim Acta (1991) 50, 587-593. PubMed Europe PubMed
Capodici,C. and Berg,R.A. Neutrophil collagenase activation: The role of oxidants and cathepsin G Agents Actions (1991) 34, 8-10. PubMed Europe PubMed
Gardi,C., Calzoni,P., Cavarra,E., Pacini,A. and Lungarella,G. An elastolytic proteinase from rabbit leukocytes: purification and partial characterization Arch Biochem Biophys (1991) 290, 229-232. PubMed Europe PubMed DOI I
Janusz,M.J. and Doherty,N.S. Degradation of cartilage matrix proteoglycan by human neutrophils involves both elastase and cathepsin G J Immunol (1991) 146, 3922-3928. PubMed Europe PubMed
[YEAR:1-8-1991]Maison,C.M., Villiers,C.L. and Colomb,M.G. Proteolysis of C3 on U937 cell plasma membranes. Purification of cathepsin G J Immunol (1-8-1991) 147, 921-926. PubMed Europe PubMed
Salvesen,G. and Enghild,J.J. Zymogen activation specificity and genomic structures of human neutrophil elastase and cathepsin G reveal a new branch of the chymotrypsinogen superfamily of serine proteinases Biomed Biochim Acta (1991) 50, 665-671. PubMed Europe PubMed
Shafer,W.M., Pohl,J., Onunka,V.C., Bangalore,N. and Travis,J. Human lysosomal cathepsin G and granzyme B share a functionally conserved broad spectrum antibacterial peptide J Biol Chem (1991) 266, 112-116. PubMed Europe PubMed

1990

[YEAR:15-8-1990]Bangalore,N., Travis,J., Onunka,V.C., Pohl,J. and Shafer,W.M. Identification of the primary antimicrobial domains in human neutrophil cathepsin G J Biol Chem (15-8-1990) 265, 13584-13588. PubMed Europe PubMed
Bjork,P. and Ohlsson,K. Purification and N-terminal amino-acid sequence analysis of rat polymorphonuclear leukocyte cathepsin G Biol Chem Hoppe Seyler (1990) 371, 595-601. PubMed Europe PubMed
Hanson,R.D., Connolly,N.L., Burnett,D., Campbell,E.J., Senior,R.M. and Ley,T.J. Developmental regulation of the human cathepsin G gene in myelomonocytic cells J Biol Chem (1990) 265, 1524-1530. PubMed Europe PubMed
Okada,Y., Tsuboi,S., Tsuda,Y., Nagamatsu,Y. and Yamamoto,J. Synthesis of a trihexacontapeptide corresponding to the sequence 8-70 of eglin c and studies on the relationship between the structure and the inhibitory activity against human leukocyte elastase, cathepsin G and alpha-chymotrypsin FEBS Lett (1990) 272, 113-116. PubMed Europe PubMed DOI
[YEAR:15-4-1990]Pratt,C.W., Tobin,R.B. and Church,F.C. Interaction of heparin cofactor II with neutrophil elastase and cathepsin G J Biol Chem (15-4-1990) 265, 6092-6097. PubMed Europe PubMed

1989

Hohn,P.A., Popescu,N.C., Hanson,R.D., Salvesen,G. and Ley,T.J. Genomic organization and chromosomal localization of the human cathepsin G gene J Biol Chem (1989) 264, 13412-13419. PubMed Europe PubMed

1987

Braun,N.J., Bodmer,J.L., Virca,G.D., Metz-Virca,G., Maschler,R., Bieth,J.G. and Schnebli,H.P. Kinetic studies on the interaction of eglin c with human leukocyte elastase and cathepsin G Biol Chem Hoppe Seyler (1987) 368, 299-308. PubMed Europe PubMed
[YEAR:21-4-1987]Salvesen,G., Farley,D., Shuman,J., Przybyla,A., Reilly,C. and Travis,J. Molecular cloning of human cathepsin G: structural similarity to mast cell and cytotoxic T lymphocyte proteinases Biochemistry (21-4-1987) 26, 2289-2293. PubMed Europe PubMed

1986

Szabo,G., Tozser,J., Aurell,L. and Elodi,P. Mapping of the substrate binding site of human leukocyte chymotrypsin (cathepsin G) using tripeptidyl-p-nitroanilide substrates Acta Biochim Biophys Hung (1986) 21, 349-362. PubMed Europe PubMed

1985

[YEAR:9-4-1985]Hemmi,K., Harper,J.W. and Powers,J.C. Inhibition of human leukocyte elastase, cathepsin G, chymotrypsin A alpha, and porcine pancreatic elastase with substituted isobenzofuranones and benzopyrandiones Biochemistry (9-4-1985) 24, 1841-1848. PubMed Europe PubMed I
Tanaka,T., Minematsu,Y., Reilly,C.F., Travis,J. and Powers,J.C. Human leukocyte cathepsin G. Subsite mapping with 4-nitroanilides, chemical modification, and effect of possible cofactors Biochemistry (1985) 24, 2040-2047. PubMed Europe PubMed

1984

Harper,J.W., Cook,R.R., Roberts,C.J., McLaughlin,B.J. and Powers,J.C. Active site mapping of the serine proteases human leukocyte elastase, cathepsin G, porcine pancreatic elastase, rat mast cell proteases I and II, bovine chymotrypsin Aalpha, and Staphylococcus aureus protease V-8 using tripeptide thiobenzyl ester substrates Biochemistry (1984) 23, 2995-3002. PubMed Europe PubMed
[YEAR:1-10-1984]Virca,G.D., Metz,G. and Schnebli,H.P. Similarities between human and rat leukocyte elastase and cathepsin G Eur J Biochem (1-10-1984) 144, 1-9. PubMed Europe PubMed

1983

Harper,J.W., Hemmi,K. and Powers,J.C. New mechanism-based serine protease inhibitors: inhibition of human leukocyte elastase, porcine pancreatic elastase, human leukocyte cathepsin G, and chymotrypsin by 3-chloroisocoumarin and 3,3-dichlorophthatide J Am Chem Soc (1983) 105, 6518-6520. I

1982

Tonnesen,M.G., Klempner,M.S., Austen,K.F. and Wintroub,B.U. Identification of a human neutrophil angiotension II-generating protease as cathepsin G J Clin Invest (1982) 69, 25-30. PubMed Europe PubMed PMC EPMC

1981

Barrett,A.J. Cathepsin G Methods Enzymol (1981) 80, 561-565. PubMed Europe PubMed DOI V

1980

[YEAR:19-8-1980]McRae,B., Nakajima,K., Travis,J. and Powers,J.C. Studies on reactivity of human leukocyte elastase, cathepsin G, and porcine pancreatic elastase toward peptides including sequences related to the reactive site of alpha 1-protease inhibitor (alpha 1-antitrypsin) Biochemistry (19-8-1980) 19, 3973-3978. PubMed Europe PubMed P
[YEAR:24-1-1980]Reilly,C.F. and Travis,J. The degradation of human lung elastin by neutrophil proteinases Biochim Biophys Acta (24-1-1980) 621, 147-157. PubMed Europe PubMed

1979

[YEAR:25-5-1979]Nakajima,K., Powers,J.C., Ashe,B.M. and Zimmerman,M. Mapping the extended substrate binding site of cathepsin G and human leukocyte elastase. Studies with peptide substrates related to the alpha 1-protease inhibitor reactive site J Biol Chem (25-5-1979) 254, 4027-4032. PubMed Europe PubMed P

1977

Blow,A.M.J. and Barrett,A.J. Action of human cathepsin G on the oxidized B chain of insulin Biochem J (1977) 161, 17-19. PubMed Europe PubMed PMC EPMC

1976

[YEAR:13-5-1976]Feinstein,G., Malemud,C.J. and Janoff,A. The inhibition of human leucocyte elastase and chymotrypsin-like protease by elastatinal and chymostatin Biochim Biophys Acta (13-5-1976) 429, 925-932. PubMed Europe PubMed I
[YEAR:1-5-1976]Starkey,P.M. and Barrett,A.J. Human cathepsin G. Catalytic and immunological properties Biochem J (1-5-1976) 155, 273-278. PubMed Europe PubMed PMC EPMC

1903

Hedin,S.G. Investigations on the proteolytic enzymes of the spleen of the ox J Physiol (1903) 30, 155-175. PubMed Europe PubMed