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Literature for peptidase S01.081: kallikrein-related peptidase 15

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates Inhibitors Pharma

(Topics flags: A Assay, M Mutation, R Splicing, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Gensemer,C., Petrucci,T., Beck,T., Daylor,V., Griggs,M., Griggs,C., Weintraub,A., Byerly,K., Guo,L., Morningstar,J., Kornblau,I., Biggs,R., Moore,K., Koren,N., Hastings,C., Oberlies,E., Zientara,E.R., Devey,E., Dooley,S., Stayer,K., Fenner,R., Singleton,K., Luzbetak,S., Bear,D., Byrd,R., Weninger,J., Bistran,E., Beeson,G., Kerns,J., Osterhaus,M., Fleck,E., Schnaudigel,J., Butler,S., Severance,S., Kendall,W., Delaney,J.R., Judge,D.P., Chen,P., Yao,H., Guz,J., Awgulewitsch,A., Kautz,S.A., Mukherjee,R., Price,R., Henderson,F., Sr., Shapiro,S., Francomano,C.A., Kovacic,J.C., Lavallee,M., Kontorovich,A.R., Berrandou,T.E., Slaugenhaupt,S.A., Milan,D., Maitland,A., Patel,S., Bouatia-Naji,N. and Norris,R.A.
    KLK15 alters connective tissues in hypermobile Ehlers-Danlos syndrome
    iScience (2025) 28, 113343-113343. PubMed  Europe PubMed DOI  PMC  EPMC
    2. 2023
  2. Lehto,T.K., Kovanen,R.M., Lintula,S., Malen,A., Sturenberg,C., Erickson,A., Pulkka,O.P., Stenman,U.H., Diamandis,E.P., Rannikko,A., Mirtti,T. and Koistinen,H.
    Prognostic impact of kallikrein-related peptidase transcript levels in prostate cancer
    Int J Cancer (2023) 153, 867-881. PubMed  Europe PubMed DOI
    3. 2020
  3. Adamopoulos,P.G., Koukouzeli FEpsilon, Kontos,C.K. and Scorilas,A.
    Identification of six novel alternative transcripts of the human kallikrein-related peptidase 15 (KLK15), using 3'RACE and high-throughput sequencing
    Gene (2020) , 144708-144708. PubMed  Europe PubMed DOI  M
    4. 2018
  4. Filippou,P.S., Ren,A.H., Bala,S., Papaioannou,M.D., Brinc,D., Prassas,I., Karakosta,T. and Diamandis,E.P.
    Biochemical characterization of human tissue kallikrein 15 and examination of its potential role in cancer
    Clin Biochem (2018) 58, 108-115. PubMed  Europe PubMed DOI
    5. 2016
  5. Karakosta,T.D., Soosaipillai,A., Diamandis,E.P., Batruch,I. and Drabovich,A.P.
    Quantification of human kallikrein-related peptidases in biological fluids by multiplatform targeted mass spectrometry assays
    Mol Cell Proteomics (2016) 15, 2863-2876. PubMed  Europe PubMed DOI  A
    6. 2013
  6. Lindahl,P., Sall,T., Bjartell,A., Johansson,A.M., Lilja,H. and Hallden,C.
    Copy number variants in the kallikrein gene cluster
    PLoS ONE (2013) 8, e69097-e69097. PubMed  Europe PubMed DOI  PMC  EPMC  M
  7. Lundwall,A.
    Old genes and new genes: The evolution of the kallikrein locus
    Thromb Haemost (2013) 110, 469-475. PubMed  Europe PubMed DOI  V
    8. 2012
  8. Batra,J. and Clements,J.A.
    Kallikrein-related peptidase 15 (prostinogen)
    [ISSN:978-0-12-407742-3] (2012) 3, 2814-2817. DOI
  9. Clements,J.A., Hooper,J.D. and Dong,Y.
    The human tissue kallikrein and kallikrein-related peptidase family
    [ISSN:978-0-12-407742-3] (2012) 3, 2747-2756. DOI
    10. 2011
  10. Batra,J., Nagle,C.M., O'Mara,T., Higgins,M., Dong,Y., Tan,O.L., Lose,F., Skeie,L.M., Srinivasan,S., Bolton,K.L., Song,H., Ramus,S.J., Gayther,S.A., Pharoah,P.D., Kedda,M.A., Spurdle,A.B. and Clements,J.A.
    A Kallikrein 15 (KLK15) single nucleotide polymorphism located close to a novel exon shows evidence of association with poor ovarian cancer survival
    BMC Cancer (2011) 11, 119-119. PubMed  Europe PubMed DOI  M
    11. 2010
  11. Rabien,A., Fritzsche,F.R., Jung,M., Tolle,A., Diamandis,E.P., Miller,K., Jung,K., Kristiansen,G. and Stephan,C.
    KLK15 is a prognostic marker for progression-free survival in patients with radical prostatectomy
    Int J Cancer (2010) 127, 2386-2394. PubMed  Europe PubMed DOI
    12. 2009
  12. Yoon,H., Blaber,S.I., Debela,M., Goettig,P., Scarisbrick,I.A. and Blaber,M.
    A completed KLK activome profile: investigation of activation profiles of KLK9, 10, and 15
    Biol Chem (2009) 390, 373-377. PubMed  Europe PubMed DOI
    13. 2008
  13. Clements,J.A.
    Reflections on the tissue kallikrein and kallikrein-related peptidase family - from mice to men - what have we learnt in the last two decades?
    Biol Chem (2008) 389, 1447-1454. PubMed  Europe PubMed DOI  V
    14. 2007
  14. Fernando,S.C., Najar,F.Z., Guo,X., Zhou,L., Fu,Y., Geisert,R.D., Roe,B.A. and DeSilva,U.
    Porcine kallikrein gene family: genomic structure, mapping, and differential expression analysis
    Genomics (2007) 89, 429-438. PubMed  Europe PubMed DOI
  15. Shaw,J.L., Grass,L., Sotiropoulou,G. and Diamandis,E.P.
    Development of an immunofluorometric assay for human kallikrein 15 (KLK15) and identification of KLK15 in tissues and biological fluids
    Clin Biochem (2007) 40, 104-110. PubMed  Europe PubMed DOI  A
  16. Yoon,H., Laxmikanthan,G., Lee,J., Blaber,S.I., Rodriguez,A., Kogot,J.M., Scarisbrick,I.A. and Blaber,M.
    Activation profiles and regulatory cascades of the human kallikrein-related peptidases
    J Biol Chem (2007) 282, 31852-31864. PubMed  Europe PubMed DOI  V
    17. 2005
  17. [YEAR:25-5-2005]Kurlender,L., Borgono,C., Michael,I.P., Obiezu,C., Elliott,M.B., Yousef,G.M. and Diamandis,E.P.
    A survey of alternative transcripts of human tissue kallikrein genes
    Biochim Biophys Acta (25-5-2005) 1755, 1-14. PubMed  Europe PubMed DOI  R
  18. [YEAR:13-1-2005]Michael,I.P., Kurlender,L., Memari,N., Yousef,G.M., Du,D., Grass,L., Stephan,C., Jung,K. and Diamandis,E.P.
    Intron retention: a common splicing event within the human kallikrein gene family
    Clin Chem (13-1-2005) 51, 506-515. PubMed  Europe PubMed DOI  R
    19. 2004
  19. Clements,J.A., Hooper,J.D., Odorico,D.M. and Dong,Y.
    The tissue kallikrein gene cluster
    [ISSN:0-12-079610-4] (2004) 2, 1569-1577.  V
    20. 2003
  20. [YEAR:15-8-2003]Yousef,G.M., Scorilas,A., Katsaros,D., Fracchioli,S., Iskander,L., Borgono,C., Rigault de la Longrais,I.A., Puopolo,M., Massobrio,M. and Diamandis,E.P.
    Prognostic value of the human kallikrein gene 15 expression in ovarian cancer
    J Clin Oncol (15-8-2003) 21, 3119-3126. PubMed  Europe PubMed DOI
    21. 2002
  21. [YEAR:18-11-2002]Yousef,G.M., Scorilas,A., Magklara,A., Memari,N., Ponzone,R., Sismondi,P., Biglia,N., Abd Ellatif,M. and Diamandis,E.P.
    The androgen-regulated gene human kallikrein 15 (KLK15) is an independent and favourable prognostic marker for breast cancer
    Br J Cancer (18-11-2002) 87, 1294-1300. PubMed  Europe PubMed DOI  PMC  EPMC
    22. 2001
  22. Clements,J., Hooper,J., Dong,Y. and Harvey,T.
    The expanded human kallikrein (KLK) gene family: genomic organisation, tissue-specific expression and potential functions
    Biol Chem (2001) 382, 5-14. PubMed  Europe PubMed DOI  V
  23. [YEAR:13-2-2001]Takayama,T.K., Carter,C.A. and Deng,T.
    Activation of prostate-specific antigen precursor (pro-PSA) by prostin, a novel human prostatic serine protease identified by degenerate PCR
    Biochemistry (13-2-2001) 40, 1679-1687. PubMed  Europe PubMed DOI
  24. [YEAR:5-1-2001]Yousef,G.M., Scorilas,A., Jung,K., Ashworth,L.K. and Diamandis,E.P.
    Molecular cloning of the human kallikrein 15 gene (KLK15). Up-regulation in prostate cancer
    J Biol Chem (5-1-2001) 276, 53-61. PubMed  Europe PubMed DOI
    25. 1994
  25. [YEAR:21-6-1994]Dihanich,M. and Spiess,M.
    A novel serine proteinase-like sequence from human brain
    Biochim Biophys Acta (21-6-1994) 1218, 225-228. PubMed  Europe PubMed DOI

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