$VAR1 = undef;

Summary for peptidase S01.081: kallikrein-related peptidase 15

Names
MEROPS Name	kallikrein-related peptidase 15
Other names	ACO protein, kallikrein 15, kallikrein hK15 (Homo sapiens), KLK15 g.p. (Homo sapiens), prostin, prostinogen

Domain architecture

MEROPS Classification
Classification	Clan PA >> Subclan PA(S) >> Family S1 >> Subfamily A >> S01.081
Holotype	kallikrein-related peptidase 15 (Homo sapiens), Uniprot accession Q9H2R5 (peptidase unit: 22-256), MERNUM MER0000064
History	Identifier created: MEROPS 5.4 (23 March 2001)

Activity
Catalytic type	Serine
NC-IUBMB	Not yet included in IUBMB recommendations.
Proteolytic events	CutDB database (1 cleavage)
Other databases	WIKIPEDIA	http://en.wikipedia.org/wiki/KLK15
Cleavage site specificity	Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern	-/-/-/R-/-/-/- (based on 1380 cleavages)

Specificity matrix

Amino acid	P4	P3	P2	P1	P1'	P2'	P3'	P4'
Gly	104	94	188	0	86	150	129	137
Pro	102	47	113	0	5	60	96	111
Ala	116	106	162	0	146	148	102	108
Val	89	96	64	0	72	102	113	98
Leu	78	128	125	0	77	167	109	106
Ile	61	57	33	0	56	86	46	51
Met	17	22	9	0	31	25	25	17
Phe	39	51	59	0	45	43	37	54
Tyr	39	33	45	0	28	40	44	33
Trp	13	16	12	0	11	17	12	13
Ser	106	123	127	0	174	89	104	113
Thr	66	112	45	0	87	72	75	64
Cys	21	24	25	0	60	26	27	34
Asn	43	46	30	0	52	40	45	35
Gln	58	66	68	0	39	52	76	60
Asp	70	50	28	0	40	53	65	79
Glu	19	20	18	0	8	24	41	53
Lys	66	60	79	58	165	52	72	67
Arg	68	82	59	1322	155	95	103	66
His	19	23	11	0	29	25	32	36

Human genetics
Gene symbol	Locus	Megabases	Ensembl	Entrez gene	Gene Cards	OMIM
KLK15	19q13.41		ENSG00000174562	55554	KLK15