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Literature for peptidase S01.029: kallikrein-related peptidase 14

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates Pharma

(Topics flags: A Assay, M Mutation, R Splicing, P Specificity, I Inhibitor, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2023
  1. Stuardo-Parada,A., Lopez-Munoz,R., Villarroel-Espindola,F., Figueroa,C.D. and Ehrenfeld,P.
    Minireview: functional roles of tissue kallikrein, kinins, and kallikrein-related peptidases in lung cancer
    Med Oncol40, 224-224. PubMed  Europe PubMed DOI  V
    2. 2021
  2. Zani,M.B., Sant'Ana,A.M., Tognato,R.C., Chagas,J.R. and Puzer,L.
    Human Tissue Kallikreins-Related Peptidases Are Targets for the Treatment of Skin Desquamation Diseases
    Front Med (Lausanne)8, 777619-777619. PubMed  Europe PubMed DOI  V
    3. 2020
  3. Gouin,O., Barbieux,C., Leturcq,F., Bonnet des Claustres,M., Petrova,E. and Hovnanian,A.
    Transgenic kallikrein 14 mice display major hair shaft defects associated with desmoglein 3 and 4 degradation, abnormal epidermal differentiation and Il-36 signature
    J Invest Dermatol140, 1184-1194. PubMed  Europe PubMed DOI
  4. Kryza,T., Bock,N., Lovell,S., Rockstroh,A., Lehman,M.L., Lesner,A., Panchadsaram,J., Silva,L.M., Srinivasan,S., Snell,C.E., Williams,E.D., Fazli,L., Gleave,M., Batra,J., Nelson,C., Tate,E.W., Harris,J., Hooper,J.D. and Clements,J.A.
    The molecular function of kallikrein-related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer
    Mol Oncol14, 105-128. PubMed  Europe PubMed DOI
    5. 2018
  5. Horn,M., Zbodakova,O., Kasparek,P., Srp,J., Haneckova,R., Hradilek,M., Mares,M. and Sedlacek,R.
    Profiling system for skin kallikrein proteolysis applied in gene-deficient mouse models
    Biol Chem399, 1085-1089. PubMed  Europe PubMed DOI  A
  6. Rose,A.M., Krishan,A., Chakarova,C.F., Moya,L., Chambers,S.K., Hollands,M., Illingworth,J.C., Williams,S.M.G., McCabe,H.E., Shah,A.Z., Palmer,C.N.A., Chakravarti,A., Berg,J.N., Batra,J. and Bhattacharya,S.S.
    MSR1 repeats modulate gene expression and affect risk of breast and prostate cancer
    Ann Oncol29, 1292-1303. PubMed  Europe PubMed DOI  M
  7. Ulbricht,D., Tindall,C.A., Oertwig,K., Hanke,S., Strater,N. and Heiker,J.T.
    Kallikrein-related peptidase 14 is the second KLK protease targeted by the serpin vaspin
    Biol Chem399, 1079-1084. PubMed  Europe PubMed DOI
    8. 2017
  8. Reid,J.C., Matsika,A., Davies,C.M., He,Y., Broomfield,A., Bennett,N.C., Magdolen,V., Srinivasan,B., Clements,J.A. and Hooper,J.D.
    Pericellular regulation of prostate cancer expressed kallikrein-related peptidases and matrix metalloproteinases by cell surface serine proteases
    Am J Cancer Res7, 2257-2274. PubMed  Europe PubMed
    9. 2016
  9. Chen,W., Kinsler,V.A., Macmillan,D. and Di,W.L.
    Tissue kallikrein inhibitors based on the sunflower trypsin inhibitor scaffold - a potential therapeutic intervention for skin diseases
    PLoS ONE11, e0166268-e0166268. PubMed  Europe PubMed DOI
  10. Karakosta,T.D., Soosaipillai,A., Diamandis,E.P., Batruch,I. and Drabovich,A.P.
    Quantification of human kallikrein-related peptidases in biological fluids by multiplatform targeted mass spectrometry assays
    Mol Cell Proteomics15, 2863-2876. PubMed  Europe PubMed DOI  A
  11. Reid,J.C., Bennett,N.C., Stephens,C.R., Carroll,M.L., Magdolen,V., Clements,J.A. and Hooper,J.D.
    In vitro evidence that KLK14 regulates the components of the HGF/Met axis, pro-HGF and HGF-activator inhibitor 1A and 1B
    Biol Chem397, 1299-1305. PubMed  Europe PubMed DOI
    12. 2013
  12. Lundwall,A.
    Old genes and new genes: The evolution of the kallikrein locus
    Thromb Haemost110, 469-475. PubMed  Europe PubMed DOI  V
  13. Tan,X., Furio,L., Reboud-Ravaux,M., Villoutreix,B.O., Hovnanian,A. and El Amri,C.
    1,2,4-Triazole derivatives as transient inactivators of kallikreins involved in skin diseases
    Bioorg Med Chem Lett23, 4547-4551. PubMed  Europe PubMed DOI  I
    14. 2012
  14. Clements,J.A., Hooper,J.D. and Dong,Y.
    The human tissue kallikrein and kallikrein-related peptidase family
    [ISSN:978-0-12-407742-3]3, 2747-2756. DOI
  15. de Veer,S.J., Swedberg,J.E., Parker,E.A. and Harris,J.M.
    Non-combinatorial library screening reveals subsite cooperativity and identifies new high-efficiency substrates for kallikrein-related peptidase 14
    Biol Chem393, 331-341. PubMed  Europe PubMed DOI  P
  16. Eissa,A. and Diamandis,E.P.
    Kallikrein-related peptidase 14
    [ISSN:978-0-12-407742-3]3, 2809-2813. DOI
  17. Lose,F., Lawrence,M.G., Srinivasan,S., O'Mara,T., Marquart,L., Chambers,S., Gardiner,R.A., Aitken,J.F., Spurdle,A.B., Batra,J. and Clements,J.A.
    The kallikrein 14 gene is down-regulated by androgen receptor signalling and harbours genetic variation that is associated with prostate tumour aggressiveness
    Biol Chem393, 403-412. PubMed  Europe PubMed DOI
    18. 2011
  18. Gratio,V., Loriot,C., Virca,G.D., Oikonomopoulou,K., Walker,F., Diamandis,E.P., Hollenberg,M.D. and Darmoul,D.
    Kallikrein-related peptidase 14 acts on proteinase-activated receptor 2 to induce signaling pathway in colon cancer cells
    Am J Pathol179, 2625-2636. PubMed  Europe PubMed DOI
    19. 2009
  19. Angelopoulou,K., Prassas,I. and Yousef,G.M.
    The canine kallikrein-related peptidase 14: structural characterization, alternative splicing and differential expression in mammary cancer
    Gene446, 68-74. PubMed  Europe PubMed DOI
    20. 2008
  20. Clements,J.A.
    Reflections on the tissue kallikrein and kallikrein-related peptidase family - from mice to men - what have we learnt in the last two decades?
    Biol Chem389, 1447-1454. PubMed  Europe PubMed DOI  V
  21. Emami,N., Deperthes,D., Malm,J. and Diamandis,E.P.
    Major role of human KLK14 in seminal clot liquefaction
    J Biol Chem283, 19561-19569. PubMed  Europe PubMed DOI
  22. Emami,N. and Diamandis,E.P.
    Human kallikrein-related peptidase 14 (KLK14) is a new activator component of the KLK proteolytic cascade. Possible function in seminal plasma and skin
    J Biol Chem283, 3031-3041. PubMed  Europe PubMed DOI
  23. Planque,C., Blechet,C., Ayadi-Kaddour,A., Heuze-Vourc'h,N., Dumont,P., Guyetant,S., Diamandis,E.P., El Mezni,F. and Courty,Y.
    Quantitative RT-PCR analysis and immunohistochemical localization of the kallikrein-related peptidases 13 and 14 in lung
    Biol Chem389, 781-786. PubMed  Europe PubMed DOI
  24. Yoon,H., Blaber,S.I., Evans,D.M., Trim,J., Juliano,M.A., Scarisbrick,I.A. and Blaber,M.
    Activation profiles of human kallikrein-related peptidases by proteases of the thrombostasis axis
    Protein Sci17, 1998-2007. PubMed  Europe PubMed DOI
    25. 2007
  25. Borgono,C.A., Gavigan,J.A., Alves,J., Bowles,B., Harris,J.L., Sotiropoulou,G. and Diamandis,E.P.
    Defining the extended substrate specificity of kallikrein 1-related peptidases
    Biol Chem388, 1215-1225. PubMed  Europe PubMed DOI  P
  26. Borgono,C.A., Michael,I.P., Shaw,J.L., Luo,L.Y., Ghosh,M.C., Soosaipillai,A., Grass,L., Katsaros,D. and Diamandis,E.P.
    Expression and functional characterization of the cancer-related serine protease, human tissue kallikrein 14
    J Biol Chem282, 2405-2422. PubMed  Europe PubMed DOI
  27. Deraison,C., Bonnart,C., Lopez,F., Besson,C., Robinson,R., Jayakumar,A., Wagberg,F., Brattsand,M., Hachem,J.P., Leonardsson,G. and Hovnanian,A.
    LEKTI fragments specifically inhibit KLK5, KLK7, and KLK14 and control desquamation through a pH-dependent interaction
    Mol Biol Cell18, 3607-3619. PubMed  Europe PubMed DOI
  28. Fernando,S.C., Najar,F.Z., Guo,X., Zhou,L., Fu,Y., Geisert,R.D., Roe,B.A. and DeSilva,U.
    Porcine kallikrein gene family: genomic structure, mapping, and differential expression analysis
    Genomics89, 429-438. PubMed  Europe PubMed DOI
  29. Rajapakse,S. and Takahashi,T.
    Expression and enzymatic characterization of recombinant human kallikrein 14
    Zoolog Sci24, 774-780. PubMed  Europe PubMed DOI  E  P
  30. Yoon,H., Laxmikanthan,G., Lee,J., Blaber,S.I., Rodriguez,A., Kogot,J.M., Scarisbrick,I.A. and Blaber,M.
    Activation profiles and regulatory cascades of the human kallikrein-related peptidases
    J Biol Chem282, 31852-31864. PubMed  Europe PubMed DOI  V
    31. 2006
  31. Felber,L.M., Kundig,C., Borgono,C.A., Chagas,J.R., Tasinato,A., Jichlinski,P., Gygi,C.M., Leisinger,H.J., Diamandis,E.P., Deperthes,D. and Cloutier,S.M.
    Mutant recombinant serpins as highly specific inhibitors of human kallikrein 14
    FEBS J273, 2505-2514. PubMed  Europe PubMed DOI
  32. Luo,L.Y. and Jiang,W.
    Inhibition profiles of human tissue kallikreins by serine protease inhibitors
    Biol Chem387, 813-816. PubMed  Europe PubMed DOI
  33. Stefansson,K., Brattsand,M., Ny,A., Glas,B. and Egelrud,T.
    Kallikrein-related peptidase 14 may be a major contributor to trypsin-like proteolytic activity in human stratum corneum
    Biol Chem387, 761-768. PubMed  Europe PubMed DOI
    34. 2005
  34. Brattsand,M., Stefansson,K., Lundh,C., Haasum,Y. and Egelrud,T.
    A proteolytic cascade of kallikreins in the stratum corneum
    J Invest Dermatol124, 198-203. PubMed  Europe PubMed DOI
  35. Felber,L.M., Borgono,C.A., Cloutier,S.M., Kundig,C., Kishi,T., Ribeiro Chagas,J., Jichlinski,P., Gygi,C.M., Leisinger,H.J., Diamandis,E.P. and Deperthes,D.
    Enzymatic profiling of human kallikrein 14 using phage-display substrate technology
    Biol Chem386, 291-298. PubMed  Europe PubMed DOI  P
  36. [YEAR:25-5-2005]Kurlender,L., Borgono,C., Michael,I.P., Obiezu,C., Elliott,M.B., Yousef,G.M. and Diamandis,E.P.
    A survey of alternative transcripts of human tissue kallikrein genes
    Biochim Biophys Acta1755, 1-14. PubMed  Europe PubMed DOI  R
    37. 2004
  37. Clements,J.A., Hooper,J.D., Odorico,D.M. and Dong,Y.
    The tissue kallikrein gene cluster
    [ISSN:0-12-079610-4]2, 1569-1577.  V
    38. 2003
  38. [YEAR:15-12-2003]Borgono,C.A., Grass,L., Soosaipillai,A., Yousef,G.M., Petraki,C.D., Howarth,D.H., Fracchioli,S., Katsaros,D. and Diamandis,E.P.
    Human kallikrein 14: a new potential biomarker for ovarian and breast cancer
    Cancer Res63, 9032-9041. PubMed  Europe PubMed
  39. [YEAR:1-9-2003]Yousef,G.M., Stephan,C., Scorilas,A., Ellatif,M.A., Jung,K., Kristiansen,G., Jung,M., Polymeris,M.E. and Diamandis,E.P.
    Differential expression of the human kallikrein gene 14 (KLK14) in normal and cancerous prostatic tissues
    Prostate56, 287-292. PubMed  Europe PubMed DOI
  40. Yousef,G.M., Fracchioli,S., Scorilas,A., Borgono,C.A., Iskander,L., Puopolo,M., Massobrio,M., Diamandis,E.P. and Katsaros,D.
    Steroid hormone regulation and prognostic value of the human kallikrein gene 14 in ovarian cancer
    Am J Clin Pathol119, 346-355. PubMed  Europe PubMed
  41. [YEAR:1-5-2003]Yousef,G.M., Polymeris,M.E., Yacoub,G.M., Scorilas,A., Soosaipillai,A., Popalis,C., Fracchioli,S., Katsaros,D. and Diamandis,E.P.
    Parallel overexpression of seven kallikrein genes in ovarian cancer
    Cancer Res63, 2223-2227. PubMed  Europe PubMed
    42. 2002
  42. [YEAR:18-11-2002]Yousef,G.M., Borgono,C.A., Scorilas,A., Ponzone,R., Biglia,N., Iskander,L., Polymeris,M.E., Roagna,R., Sismondi,P. and Diamandis,E.P.
    Quantitative analysis of human kallikrein gene 14 expression in breast tumours indicates association with poor prognosis
    Br J Cancer87, 1287-1293. PubMed  Europe PubMed DOI
    43. 2001
  43. Clements,J., Hooper,J., Dong,Y. and Harvey,T.
    The expanded human kallikrein (KLK) gene family: genomic organisation, tissue-specific expression and potential functions
    Biol Chem382, 5-14. PubMed  Europe PubMed DOI  V
  44. [YEAR:1-4-2001]Hooper,J.D., Bui,L.T., Rae,F.K., Harvey,T.J., Myers,S.A., Ashworth,L.K. and Clements,J.A.
    Identification and characterization of KLK14, a novel kallikrein serine protease gene located on human chromosome 19q13.4 and expressed in prostate and skeletal muscle
    Genomics73, 117-122. PubMed  Europe PubMed DOI
  45. [YEAR:15-4-2001]Yousef,G.M., Magklara,A., Chang,A., Jung,K., Katsaros,D. and Diamandis,E.P.
    Cloning of a new member of the human kallikrein gene family, KLK14, which is down-regulated in different malignancies
    Cancer Res61, 3425-3431. PubMed  Europe PubMed
    46. 2000
  46. Diamandis,E.P., Yousef,G.M., Luo,L.Y., Magklara,A. and Obiezu,C.V.
    The new human kallikrein gene family: implications in carcinogenesis
    Trends Endocrinol Metab11, 54-60. PubMed  Europe PubMed DOI
    47. 1994
  47. [YEAR:15-7-1994]Southard-Smith,M., Pierce,J.C. and Macdonald,R.J.
    Physical mapping of the rat tissue kallikrein family in two gene clusters by analysis of P1 bacteriophage clones
    Genomics22, 404-417. PubMed  Europe PubMed DOI
    48. 1992
  48. Berg,T., Bradshaw,R.A., Carretero,O.A., Chao,J., Chao,L., Clements,J.A., Fahnestock,M., Fritz,H., Gauthier,F. and Macdonald,R.J.
    A common nomenclature for members of the tissue (glandular) kallikrein gene families
    Agents Actions Suppl38, 19-25. PubMed  Europe PubMed DOI

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