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Literature for peptidase S01.017: kallikrein-related peptidase 5

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: A Assay, S Structure, T Target, P Specificity, K Knockout, E Expression, V Review, M Mutation, R Splicing, I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)

    2024
  1. Kim,H., Kang,Y., Kim,S., Park,D., Heo,S.Y., Yoo,J.S., Choi,I., N,M.P.A., Ahn,J.W., Yang,J.S., Bak,N., Kim,K.K., Lee,J.Y. and Choi,Y.K.
    The host protease KLK5 primes and activates spike proteins to promote human betacoronavirus replication and lung inflammation
    Sci Signal17, eadn3785-eadn3785. PubMed  Europe PubMed DOI
    2. 2023
  2. Stuardo-Parada,A., Lopez-Munoz,R., Villarroel-Espindola,F., Figueroa,C.D. and Ehrenfeld,P.
    Minireview: functional roles of tissue kallikrein, kinins, and kallikrein-related peptidases in lung cancer
    Med Oncol40, 224-224. PubMed  Europe PubMed DOI  V
    3. 2022
  3. Gonschorek,P., Zorzi,A., Maric,T., Le Jeune,M., Schuttel,M., Montagnon,M., Gomez-Ojea,R., Vollmar,D.P., Whitfield,C., Reymond,L., Carle,V., Verma,H., Schilling,O., Hovnanian,A. and Heinis,C.
    Phage Display Selected Cyclic Peptide Inhibitors of Kallikrein-Related Peptidases 5 and 7 and Their In Vivo Delivery to the Skin
    J Med Chem65, 9735-9749. PubMed  Europe PubMed DOI
  4. Jackman,J.K., Stockwell,A., Choy,D.F., Xie,M.M., Lu,P., Jia,G., Li,H., Abbas,A.R., Bronson,P.G., Lin,W.Y., Chiu,C.P.C., Maun,H.R., Roose-Girma,M., Tam,L., Zhang,J., Modrusan,Z., Graham,R.R., Behrens,T.W., White,S.R., Naureckas,T., Ober,C., Ferreira,M., Sedlacek,R., Wu,J., Lee,W.P., Lazarus,R.A., Koerber,J.T., Arron,J.R., Yaspan,B.L. and Yi,T.
    Genome-wide association study identifies kallikrein 5 in type 2 inflammation-low asthma
    J Allergy Clin Immunol150, 972-978. PubMed  Europe PubMed DOI
  5. Zhou,S., Liu,S., Tian,G., Zhao,L., Wang,H., Li,Y., Shen,Y. and Han,L.
    KLK5 is associated with the radioresistance, aggression, and progression of cervical cancer
    Gynecol Oncol166, 138-147. PubMed  Europe PubMed DOI
  6. Zingkou,E., Pampalakis,G. and Sotiropoulou,G.
    Cocktails of KLK5 Protease Inhibitors and Anti-TNFalpha Therapeutics: an Effective Treatment for Netherton Syndrome
    J Clin Immunol PubMed  Europe PubMed DOI
    7. 2021
  7. Almaraz-Giron,M.A., Calderon-Jaimes,E., Carrillo,A.S., Diaz-Cervantes,E., Alonso,E.C., Islas-Jacome,A., Dominguez-Ortiz,A. and Castanon-Alonso,S.L.
    Search for Non-Protein Protease Inhibitors Constituted with an Indole and Acetylene Core
    Molecules26, PubMed  Europe PubMed DOI
  8. Kim,J., Kim,M.G., Jeong,S.H., Kim,H.J. and Son,S.W.
    STAT3 maintains skin barrier integrity by modulating SPINK5 and KLK5 expression in keratinocytes
    Exp Dermatol PubMed  Europe PubMed DOI  K
  9. Lavergne,M., Guillon-Munos,A., Lenga Ma Bonda,W., Attucci,S., Kryza,T., Barascu,A., Moreau,T., Petit-Court, Sizaret,D., Courty,Y., Iochmann,S. and Reverdiau,P.
    Tissue factor pathway inhibitor 2 is a potent kallikrein-related protease 12 inhibitor
    Biol Chem PubMed  Europe PubMed DOI
  10. Lenga Ma Bonda,W., Lavergne,M., Vasseur,V., Brisson,L., Roger,S., Legras,A., Guillon,A., Guyetant,S., Hiemstra,P.S., Si-Tahar,M., Iochmann,S. and Reverdiau,P.
    Kallikrein-related peptidase 5 contributes to the remodeling and repair of bronchial epithelium
    FASEB J35, e21838-e21838. PubMed  Europe PubMed DOI  K
  11. Zani,M.B., Sant'Ana,A.M., Tognato,R.C., Chagas,J.R. and Puzer,L.
    Human Tissue Kallikreins-Related Peptidases Are Targets for the Treatment of Skin Desquamation Diseases
    Front Med (Lausanne)8, 777619-777619. PubMed  Europe PubMed DOI  V
    12. 2020
  12. Alves,M.G., Kodama,M.H., da Silva,E.Z.M., Gomes,B.B.M., da Silva,R.A.A., Vieira,G.V., Alves,V.M., da Fonseca,C.K., Santana,A.C., Cecilio,N.T., Costa,M.S.A., Jamur,M.C., Oliver,C., Cunha,T.M., Bugge,T.H., Braz-Silva,P.H., Colli,L.M. and Sales,K.U.
    Relative expression of KLK5 to LEKTI is associated with aggressiveness of oral squamous cell carcinoma
    Transl Oncol14, 100970-100970. PubMed  Europe PubMed DOI
  13. Azouz,N.P., Klingler,A.M., Pathre,P., Besse,J.A., Baruch-Morgenstern,N.B., Ballaban,A.Y., Osswald,G.A., Brusilovsky,M., Habel,J.E., Caldwell,J.M., Ynga-Durand,M.A., Abonia,P.J., Hu,Y.C., Wen,T. and Rothenberg,M.E.
    Functional role of kallikrein 5 and proteinase-activated receptor 2 in eosinophilic esophagitis
    Sci Transl Med12, PubMed  Europe PubMed DOI
  14. Chang,J.S., Kim,N., Kim,J.Y., Do,S.I., Cho,Y., Kim,H.S. and Kim,Y.B.
    Kallikrein 5 overexpression is associated with poor prognosis in uterine cervical cancer
    J Gynecol Oncol31, e78-e78. PubMed  Europe PubMed DOI
  15. Fukagawa,S., Takahashi,A., Sayama,K., Mori,S. and Murase,T.
    Carbon dioxide ameliorates reduced desquamation in dry scaly skin via protease activation
    Int J Cosmet Sci PubMed  Europe PubMed DOI
  16. Zingkou,E., Pampalakis,G. and Sotiropoulou,G.
    Exacerbated dandruff in the absence of kallikrein-related peptidase 5 protease
    J Dermatol47, 311-313. PubMed  Europe PubMed DOI
    17. 2019
  17. Di Paolo,C.T., Filippou,P.S., Yu,Y., Poda,G., Diamandis,E.P. and Prassas,I.
    Screening of chemical libraries in pursuit of kallikrein-5 specific inhibitors for the treatment of inflammatory dermatoses
    Clin Chem Lab Med57, 1737-1743. PubMed  Europe PubMed DOI  I
  18. Pampalakis,G., Zingkou,E., Kaklamanis,L., Spella,M., Stathopoulos,G.T. and Sotiropoulou,G.
    Elimination of KLK5 inhibits early skin tumorigenesis by reducing epidermal proteolysis and reinforcing epidermal microstructure
    Biochim Biophys Acta Mol Basis Dis1865, 165520-165520. PubMed  Europe PubMed DOI  K
  19. Thorpe,J.H., Edgar,E.V., Smith,K.J., Lewell,X.Q., Rella,M., White,G.V., Polyakova,O., Nassau,P., Walker,A.L., Holmes,D.S., Pearce,A.C., Wang,Y., Liddle,J. and Hovnanian,A.
    Evaluation of a crystallographic surrogate for kallikrein 5 in the discovery of novel inhibitors for Netherton syndrome
    Acta Crystallogr F Struct Biol Commun75, 385-391. PubMed  Europe PubMed DOI  S
  20. Walker,A.L., Denis,A., Bingham,R.P., Boulliot,A., Edgar,E.V., Ferrie,A., Holmes,D.S., Laroze,A., Liddle,J., Fouchet,M.H., Moquette,A., Nassau,P., Pearce,A.C., Polyakova,O., Smith,K.J., Thomas,P., Thorpe,J.H., Trottet,L., Wang,Y. and Hovnanian,A.
    Design and development of a series of borocycles as selective, covalent kallikrein 5 inhibitors
    Bioorg Med Chem Lett29, 126675-126675. PubMed  Europe PubMed DOI  I
  21. Walker,A.L., Bingham,R.P., Edgar,E.V., Ferrie,A., Holmes,D.S., Liddle,J., Polyakova,O., Rella,M., Smith,K.J., Thorpe,J.H., Wang,Y., White,G.V., Young,R.J. and Hovnanian,A.
    Structure guided drug design to develop kallikrein 5 inhibitors to treat Netherton syndrome
    Bioorg Med Chem Lett29, 1454-1458. PubMed  Europe PubMed DOI  I
  22. White,G.V., Edgar,E.V., Holmes,D.S., Lewell,X.Q., Liddle,J., Polyakova,O., Smith,K.J., Thorpe,J.H., Walker,A.L., Wang,Y., Young,R.J. and Hovnanian,A.
    Kallikrein 5 inhibitors identified through structure based drug design in search for a treatment for Netherton Syndrome
    Bioorg Med Chem Lett29, 821-825. PubMed  Europe PubMed DOI  M  I
    23. 2018
  23. Grunberg,M., Quandt,D., Cynis,H., Demuth,H.U., Kindermann,A., Magdolen,V., Forssmann,W.G., Seliger,B. and Magert,H.J.
    Kallikrein-related peptidases are activators of the CC chemokine CCL14
    Eur J Immunol48, 1592-1594. PubMed  Europe PubMed DOI
  24. Horn,M., Zbodakova,O., Kasparek,P., Srp,J., Haneckova,R., Hradilek,M., Mares,M. and Sedlacek,R.
    Profiling system for skin kallikrein proteolysis applied in gene-deficient mouse models
    Biol Chem399, 1085-1089. PubMed  Europe PubMed DOI  A
  25. Loessner,D., Goettig,P., Preis,S., Felber,J., Bronger,H., Clements,J.A., Dorn,J. and Magdolen,V.
    Kallikrein-related peptidases represent attractive therapeutic targets for ovarian cancer
    Expert Opin Ther Targets22, 745-763. PubMed  Europe PubMed DOI  T
  26. Magnen,M., Elsasser,B.M., Zbodakova,O., Kasparek,P., Gueugnon,F., Petit-Courty,A., Sedlacek,R., Goettig,P. and Courty,Y.
    Kallikrein-related peptidase 5 and seasonal influenza viruses, limitations of the experimental models for activating proteases
    Biol Chem399, 1053-1064. PubMed  Europe PubMed DOI
    27. 2017
  27. Adamopoulos,P.G., Kontos,C.K. and Scorilas,A.
    Molecular cloning of novel transcripts of human kallikrein-related peptidases 5, 6, 7, 8 and 9 (KLK5 - KLK9), using Next-generation sequencing
    Sci Rep7, 17299-17299. PubMed  Europe PubMed DOI  M
  28. Fang,X., Bagui,S. and Bagui,S.
    Improving virtual screening predictive accuracy of human kallikrein 5 inhibitors using machine learning models
    Comput Biol Chem69, 110-119. PubMed  Europe PubMed DOI  I
  29. Kasparek,P., Ileninova,Z., Zbodakova,O., Kanchev,I., Benada,O., Chalupsky,K., Brattsand,M., Beck,I.M. and Sedlacek,R.
    KLK5 and KLK7 ablation fully rescues lethality of Netherton syndrome-like phenotype
    PLoS Genet13, e1006566-e1006566. PubMed  Europe PubMed DOI  K
  30. Matsubara,Y., Matsumoto,T., Koseki,J., Kaneko,A., Aiba,S. and Yamasaki,K.
    Inhibition of human kallikrein 5 protease by triterpenoids from natural sources
    Molecules22, PubMed  Europe PubMed DOI  I
  31. McGovern,J.A., Meinert,C., deVeer,S.J., Hollier,B.G., Parker,T.J. and Upton,Z.
    Attenuated kallikrein-related peptidase activity disrupts desquamation and leads to stratum corneum thickening in human skin equivalent models
    Br J Dermatol176, 145-158. PubMed  Europe PubMed DOI
  32. Nargis,T., Kumar,K., Ghosh,A.R., Sharma,A., Rudra,D., Sen,D., Chakrabarti,S., Mukhopadhyay,S., Ganguly,D. and Chakrabarti,P.
    KLK5 induces shedding of DPP4 from circulatory Th17 cells in type 2 diabetes
    Mol Metab6, 1529-1539. PubMed  Europe PubMed DOI
    33. 2016
  33. Chen,W., Kinsler,V.A., Macmillan,D. and Di,W.L.
    Tissue kallikrein inhibitors based on the sunflower trypsin inhibitor scaffold - a potential therapeutic intervention for skin diseases
    PLoS ONE11, e0166268-e0166268. PubMed  Europe PubMed DOI
  34. de Veer,S.J., Swedberg,J.E., Brattsand,M., Clements,J.A. and Harris,J.M.
    Exploring the active site binding specificity of kallikrein-related peptidase 5 (KLK5) guides the design of new peptide substrates and inhibitors
    Biol Chem397, 1237-1249. PubMed  Europe PubMed DOI  P
  35. Hoelz,L.V., Zorzanelli,B.C., Azevedo,P.H., Passos,S.G., de Souza,L.R., Zani,M., Pinheiro,S., Puzer,L., Dias,L.R. and Muri,E.M.
    Synthesis, biological evaluation and molecular modeling of pseudo-peptides based statine as inhibitors for human tissue kallikrein 5
    Eur J Med Chem112, 39-47. PubMed  Europe PubMed DOI  I
  36. Kalinska,M., Meyer-Hoffert,U., Kantyka,T. and Potempa,J.
    Kallikreins - the melting pot of activity and function
    Biochimie122, 270-282. PubMed  Europe PubMed DOI  V
  37. Karakosta,T.D., Soosaipillai,A., Diamandis,E.P., Batruch,I. and Drabovich,A.P.
    Quantification of human kallikrein-related peptidases in biological fluids by multiplatform targeted mass spectrometry assays
    Mol Cell Proteomics15, 2863-2876. PubMed  Europe PubMed DOI  A
    38. 2015
  38. Severino,B., Fiorino,F., Corvino,A., Caliendo,G., Santagada,V., Assis,D.M., Oliveira,J.R., Juliano,L., Manganelli,S., Benfenati,E., Frecentese,F., Perissutti,E. and Juliano,M.A.
    Synthesis, biological evaluation, and docking studies of PAR2-AP-derived pseudopeptides as inhibitors of kallikrein 5 and 6
    Biol Chem396, 45-52. PubMed  Europe PubMed DOI  I
  39. Tan,X., Soualmia,F., Furio,L., Renard,J.F., Kempen,I., Qin,L., Pagano,M., Pirotte,B., El Amri,C., Hovnanian,A. and Reboud-Ravaux,M.
    Toward the first class of suicide inhibitors of kallikreins involved in skin diseases
    J Med Chem58, 598-612. PubMed  Europe PubMed DOI  I
    40. 2014
  40. Furio,L., de Veer,S., Jaillet,M., Briot,A., Robin,A., Deraison,C. and Hovnanian,A.
    Transgenic kallikrein 5 mice reproduce major cutaneous and systemic hallmarks of Netherton syndrome
    J Exp Med211, 499-513. PubMed  Europe PubMed DOI
  41. Pampalakis,G., Obasuyi,O., Papadodima,O., Chatziioannou,A., Zoumpourlis,V. and Sotiropoulou,G.
    The KLK5 protease suppresses breast cancer by repressing the mevalonate pathway
    Oncotarget5, 2390-2403. PubMed  Europe PubMed
  42. Shariff,L., Zhu,Y., Cowper,B., Di,W.-L. and Macmillan,D.
    Sunflower trypsin inhibitor (SFTI-1) analogues of synthetic and biological origin via N-->S acyl transfer: potential inhibitors of human kallikrein-5 (KLK5)
    Tetrahedron70, 7675-7680. DOI
  43. Two,A.M. and Del Rosso,J.Q.
    Kallikrein 5-mediated inflammation in rosacea: clinically relevant correlations with acute and chronic manifestations in rosacea and how individual treatments may provide therapeutic benefit
    J Clin Aesthet Dermatol7, 20-25. PubMed  Europe PubMed
    44. 2013
  44. de Souza,L.R., Melo,M., Paschoalin,T., Carmona,A.K., Kondo,M., Hirata,I.Y., Blaber,M., Tersariol,I., Takatsuka,J., Juliano,M.A., Juliano,L., Gomes,R.A. and Puzer,L.
    Human tissue kallikreins 3 and 5 can act as plasminogen activator releasing active plasmin
    Biochem Biophys Res Commun433, 333-337. PubMed  Europe PubMed DOI
  45. Hamilton,B.S. and Whittaker,G.R.
    Cleavage activation of human-adapted influenza virus subtypes by kallikrein-related peptidases 5 and 12
    J Biol Chem288, 17399-17407. PubMed  Europe PubMed DOI
  46. Lose,F., Batra,J., O'Mara,T., Fahey,P., Marquart,L., Eeles,R.A., Easton,D.F., Al Olama,A.A., Kote-Jarai,Z., Guy,M., Muir,K., Lophatananon,A., Rahman,A.A., Neal,D.E., Hamdy,F.C., Donovan,J.L., Chambers,S., Gardiner,R.A., Aitken,J.F., Yaxley,J., Alexander,K., Clements,J.A., Spurdle,A.B. and Kedda,M.A.
    Common variation in kallikrein genes KLK5, KLK6, KLK12, and KLK13 and risk of prostate cancer and tumor aggressiveness
    Urol Oncol31, 635-643. PubMed  Europe PubMed DOI  M
  47. Lundwall,A.
    Old genes and new genes: The evolution of the kallikrein locus
    Thromb Haemost110, 469-475. PubMed  Europe PubMed DOI  V
  48. Sakabe,J., Yamamoto,M., Hirakawa,S., Motoyama,A., Ohta,I., Tatsuno,K., Ito,T., Kabashima,K., Hibino,T. and Tokura,Y.
    Kallikrein-related peptidase 5 functions in proteolytic processing of profilaggrin in cultured human keratinocytes
    J Biol Chem288, 17179-17189. PubMed  Europe PubMed DOI
  49. Tan,X., Furio,L., Reboud-Ravaux,M., Villoutreix,B.O., Hovnanian,A. and El Amri,C.
    1,2,4-Triazole derivatives as transient inactivators of kallikreins involved in skin diseases
    Bioorg Med Chem Lett23, 4547-4551. PubMed  Europe PubMed DOI  I
    50. 2012
  50. Britland,S. and Hoyle,M.
    Transcriptional gene silencing of kallikrein 5 and kallikrein 7 using siRNA prevents epithelial cell detachment induced by alkaline shock in an in vitro model of eczema
    Biotechnol Prog28, 485-489. PubMed  Europe PubMed DOI
  51. Clements,J.A., Hooper,J.D. and Dong,Y.
    The human tissue kallikrein and kallikrein-related peptidase family
    [ISSN:978-0-12-407742-3]3, 2747-2756. DOI
  52. Goettig,P. and Magdolen,V.
    Kallikrein-related peptidase 5
    [ISSN:978-0-12-407742-3]3, 2772-2778. DOI
    53. 2011
  53. Jiang,R., Shi,Z., Johnson,J.J., Liu,Y. and Stack,M.S.
    Kallikrein-5 promotes cleavage of desmoglein-1 and loss of cell-cell cohesion in oral squamous cell carcinoma
    J Biol Chem286, 9127-9135. PubMed  Europe PubMed DOI
  54. Teixeira,T.S., Freitas,R.F., Abrahao,O., Jr., Devienne,K.F., de Souza,L.R., Blaber,S.I., Blaber,M., Kondo,M.Y., Juliano,M.A., Juliano,L. and Puzer,L.
    Biological evaluation and docking studies of natural isocoumarins as inhibitors for human kallikrein 5 and 7
    Bioorg Med Chem Lett21, 6112-6115. PubMed  Europe PubMed DOI  I
    55. 2010
  55. Angelopoulou,K. and Karagiannis,G.S.
    Structural characterization and expression of five novel canine kallikrein-related peptidases in mammary cancer
    Mamm Genome21, 516-524. PubMed  Europe PubMed DOI
    56. 2009
  56. Briot,A., Deraison,C., Lacroix,M., Bonnart,C., Robin,A., Besson,C., Dubus,P. and Hovnanian,A.
    Kallikrein 5 induces atopic dermatitis-like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome
    J Exp Med206, 1135-1147. PubMed  Europe PubMed DOI
    57. 2008
  57. Clements,J.A.
    Reflections on the tissue kallikrein and kallikrein-related peptidase family - from mice to men - what have we learnt in the last two decades?
    Biol Chem389, 1447-1454. PubMed  Europe PubMed DOI  V
  58. Debela,M., Beaufort,N., Magdolen,V., Schechter,N.M., Craik,C.S., Schmitt,M., Bode,W. and Goettig,P.
    Structures and specificity of the human kallikrein-related peptidases KLK 4, 5, 6, and 7
    Biol Chem389, 623-632. PubMed  Europe PubMed DOI  P  S
  59. Dong,Y., Matigian,N., Harvey,T.J., Samaratunga,H., Hooper,J.D. and Clements,J.A.
    Tissue-specific promoter utilisation of the kallikrein-related peptidase genes, KLK5 and KLK7, and cellular localisation of the encoded proteins suggest roles in exocrine pancreatic function
    Biol Chem389, 99-109. PubMed  Europe PubMed DOI
  60. Mukai,S., Fukushima,T., Naka,D., Tanaka,H., Osada,Y. and Kataoka,H.
    Activation of hepatocyte growth factor activator zymogen (pro-HGFA) by human kallikrein 1-related peptidases
    FEBS J275, 1003-1017. PubMed  Europe PubMed DOI
  61. Stefansson,K., Brattsand,M., Roosterman,D., Kempkes,C., Bocheva,G., Steinhoff,M. and Egelrud,T.
    Activation of proteinase-activated receptor-2 by human kallikrein-related peptidases
    J Invest Dermatol128, 18-25. PubMed  Europe PubMed DOI
    62. 2007
  62. Borgono,C.A., Gavigan,J.A., Alves,J., Bowles,B., Harris,J.L., Sotiropoulou,G. and Diamandis,E.P.
    Defining the extended substrate specificity of kallikrein 1-related peptidases
    Biol Chem388, 1215-1225. PubMed  Europe PubMed DOI  P
  63. Debela,M., Goettig,P., Magdolen,V., Huber,R., Schechter,N.M. and Bode,W.
    Structural basis of the zinc inhibition of human tissue kallikrein 5
    J Mol Biol373, 1017-1031. PubMed  Europe PubMed DOI  S
  64. Deraison,C., Bonnart,C., Lopez,F., Besson,C., Robinson,R., Jayakumar,A., Wagberg,F., Brattsand,M., Hachem,J.P., Leonardsson,G. and Hovnanian,A.
    LEKTI fragments specifically inhibit KLK5, KLK7, and KLK14 and control desquamation through a pH-dependent interaction
    Mol Biol Cell18, 3607-3619. PubMed  Europe PubMed DOI
  65. Fernando,S.C., Najar,F.Z., Guo,X., Zhou,L., Fu,Y., Geisert,R.D., Roe,B.A. and DeSilva,U.
    Porcine kallikrein gene family: genomic structure, mapping, and differential expression analysis
    Genomics89, 429-438. PubMed  Europe PubMed DOI
  66. Shinoda,Y., Kozaki,K., Imoto,I., Obara,W., Tsuda,H., Mizutani,Y., Shuin,T., Fujioka,T., Miki,T. and Inazawa,J.
    Association of KLK5 overexpression with invasiveness of urinary bladder carcinoma cells
    Cancer Sci98, 1078-1086. PubMed  Europe PubMed DOI
  67. Yoon,H., Laxmikanthan,G., Lee,J., Blaber,S.I., Rodriguez,A., Kogot,J.M., Scarisbrick,I.A. and Blaber,M.
    Activation profiles and regulatory cascades of the human kallikrein-related peptidases
    J Biol Chem282, 31852-31864. PubMed  Europe PubMed DOI  V
    68. 2006
  68. [YEAR:1-6-2006]Debela,M., Magdolen,V., Schechter,N., Valachova,M., Lottspeich,F., Craik,C.S., Choe,Y., Bode,W. and Goettig,P.
    Specificity profiling of seven human tissue kallikreins reveals individual subsite preferences
    J Biol Chem281, 25678-25688. PubMed  Europe PubMed DOI  P
  69. Luo,L.Y. and Jiang,W.
    Inhibition profiles of human tissue kallikreins by serine protease inhibitors
    Biol Chem387, 813-816. PubMed  Europe PubMed DOI
  70. [YEAR:3-3-2006]Michael,I.P., Pampalakis,G., Mikolajczyk,S.D., Malm,J., Sotiropoulou,G. and Diamandis,E.P.
    Human tissue kallikrein 5 is a member of a proteolytic cascade pathway involved in seminal clot liquefaction and potentially in prostate cancer progression
    J Biol Chem281, 12743-12750. PubMed  Europe PubMed DOI
  71. Prezas,P., Arlt,M.J., Viktorov,P., Soosaipillai,A., Holzscheiter,L., Schmitt,M., Talieri,M., Diamandis,E.P., Kruger,A. and Magdolen,V.
    Overexpression of the human tissue kallikrein genes KLK4, 5, 6, and 7 increases the malignant phenotype of ovarian cancer cells
    Biol Chem387, 807-811. PubMed  Europe PubMed DOI
  72. Rajapakse,S., Ogiwara,K., Yamano,N., Kimura,A., Hirata,K., Takahashi,S. and Takahashi,T.
    Characterization of mouse tissue kallikrein 5
    Zoolog Sci23, 963-968. PubMed  Europe PubMed DOI
    73. 2005
  73. Brattsand,M., Stefansson,K., Lundh,C., Haasum,Y. and Egelrud,T.
    A proteolytic cascade of kallikreins in the stratum corneum
    J Invest Dermatol124, 198-203. PubMed  Europe PubMed DOI
  74. Egelrud,T., Brattsand,M., Kreutzmann,P., Walden,M., Vitzithum,K., Marx,U.C., Forssmann,W.G. and Magert,H.J.
    hK5 and hK7, two serine proteinases abundant in human skin, are inhibited by LEKTI domain 6
    Br J Dermatol153, 1200-1203. PubMed  Europe PubMed DOI  P
  75. [YEAR:25-5-2005]Kurlender,L., Borgono,C., Michael,I.P., Obiezu,C., Elliott,M.B., Yousef,G.M. and Diamandis,E.P.
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