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Literature for peptidase M35.004: peptidyl-Lys metallopeptidase

Summary Alignment Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: A Assay, S Structure, P Specificity, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Ahmed,U., Ochsenreither,K. and Eisele,T.<br>Production and application of peptidyl-lys metalloendopeptidase: advances, challenges, and future perspectives<br>Appl Microbiol Biotechnol (2025) 109, 88-88. PubMed  Europe PubMed DOI  PMC  EPMC
    2. 2024
  2. Ahmed,U., Stadelmann,T., Heid,D., Wurtz,B., Pfannstiel,J., Ochsenreither,K. and Eisele,T.<br>A novel, robust peptidyl-lys metalloendopeptidase from Trametes coccinea recombinantly expressed in Komagataella phaffii<br>Appl Microbiol Biotechnol (2024) 108, 103-103. PubMed  Europe PubMed DOI  PMC  EPMC
    3. 2020
  3. Zhao,M., Hao,B., Li,H., Cai,M., Xie,J., Liu,H., Tan,M., Zhai,L. and Yu,Q.<br>Peptidyl-Lys metalloendopeptidase (Lys-N) purified from dry fruit of Grifola frondosa demonstrates "mirror" digestion property with lysyl endopeptidase (Lys-C)<br>Rapid Commun Mass Spectrom (2020) 34, e8573-e8573. PubMed  Europe PubMed DOI
    4. 2016
  4. Giansanti,P., Tsiatsiani,L., Low,T.Y. and Heck,A.J.<br>Six alternative proteases for mass spectrometry-based proteomics beyond trypsin<br>Nat Protoc (2016) 11, 993-1006. PubMed  Europe PubMed DOI
  5. Odum,A.S., Ostergaard,S., Norby,I., Meldal,M. and Olesen,K.<br>Novel application of peptidyl-Lys metallopeptidase as a C-terminal processing protease<br>Protein Pept Lett (2016) 23, 396-403. PubMed  Europe PubMed  P
  6. Odum,A.S., Ostergaard,S., Norby,I., Meldal,M. and Olesen,K.<br>Heterologous expression of peptidyl-Lys metallopeptidase of Armillaria mellea and mutagenic analysis of the recombinant peptidase<br>J Biochem (2016) 159, 461-470. PubMed  Europe PubMed DOI  E
    7. 2015
  7. Odum,A.S., Olesen,K., Ostergaard,S., Thim,L., Norby,I. and Meldal,M.<br>Substrate specificity profiling of peptidyl-Lys metallopeptidase of Armillaria mellea by FRET based peptide library<br>Protein Pept Lett (2015) 22, 514-524. PubMed  Europe PubMed  P
    8. 2014
  8. Gershon,P.D.<br>Cleaved and missed sites for trypsin, Lys-C, and Lys-N can be predicted with high confidence on the basis of sequence context<br>J Proteome Res (2014) 13, 702-709. PubMed  Europe PubMed DOI  P
    9. 2012
  9. Heck,A.J.R.<br>Peptidyl-Lys metalloendopeptidase<br>[ISSN:978-0-12-407744-7] (2012) 3, 1266-1270. DOI
    10. 2011
  10. Kishimoto,T., Kondo,J., Takai-Igarashi,T. and Tanaka,H.<br>Accurate mass comparison coupled with two endopeptidases enables identification of protein termini<br>Proteomics (2011) 11, 485-489. PubMed  Europe PubMed DOI
    11. 2010
  11. Raijmakers,R., Neerincx,P., Mohammed,S. and Heck,A.J.<br>Cleavage specificities of the brother and sister proteases Lys-C and Lys-N<br>Chem Commun (Camb) (2010) 46, 8827-8829. PubMed  Europe PubMed DOI  P
  12. Taouatas,N., Heck,A.J. and Mohammed,S.<br>Evaluation of metalloendopeptidase Lys-N protease performance under different sample handling conditions<br>J Proteome Res (2010) 9, 4282-4288. PubMed  Europe PubMed DOI
    13. 2009
  13. Boersema,P.J., Taouatas,N., Altelaar,A.F., Gouw,J.W., Ross,P.L., Pappin,D.J., Heck,A.J. and Mohammed,S.<br>Straightforward and de novo peptide sequencing by MALDI-MS/MS using a Lys-N metalloendopeptidase<br>Mol Cell Proteomics (2009) 8, 650-660. PubMed  Europe PubMed DOI  PMC  EPMC
  14. Hohmann,L., Sherwood,C., Eastham,A., Peterson,A., Eng,J.K., Eddes,J.S., Shteynberg,D. and Martin,D.B.<br>Proteomic analyses using Grifola frondosa metalloendoprotease Lys-N<br>J Proteome Res (2009) 8, 1415-1422. PubMed  Europe PubMed DOI  PMC  EPMC
    15. 2008
  15. Taouatas,N., Drugan,M.M., Heck,A.J. and Mohammed,S.<br>Straightforward ladder sequencing of peptides using a Lys-N metalloendopeptidase<br>Nat Methods (2008) 5, 405-407. PubMed  Europe PubMed DOI
    16. 2005
  16. Rao,K.C., Carruth,R.T. and Miyagi,M.<br>Proteolytic 18O labeling by peptidyl-Lys metalloendopeptidase for comparative proteomics<br>J Proteome Res (2005) 4, 507-514. PubMed  Europe PubMed DOI
    17. 2004
  17. Takio,K.<br>Peptidyl-Lys metalloendopeptidase<br>[ISSN:0-12-079610-4] (2004) 2, 788-792.  V
    18. 2003
  18. Abe,M. and Seguchi,M.<br>Proteases of Maitake (Grifola frondosa) responsible for breakdown of wheat flour dough and their reaction with gluten proteins<br>Biosci Biotechnol Biochem (2003) 67, 2018-2021. PubMed  Europe PubMed DOI
    19. 2002
  19. Saito,T., Dohmae,N., Tsujimoto,M. and Takio,K.<br>PCR cloning and heterologous expression of cDNA encoding a peptidyl-Lys metalloendopeptidase precursor of Grifola frondosa<br>J Gen Appl Microbiol (2002) 48, 287-292. PubMed  Europe PubMed DOI
    20. 2001
  20. Hori,T., Kumasaka,T., Yamamoto,M., Nonaka,T., Tanaka,N., Hashimoto,Y., Ueki,T. and Takio,K.<br>Structure of a new 'aspzincin' metalloendopeptidase from Grifola frondosa: implications for the catalytic mechanism and substrate specificity based on several different crystal forms<br>Acta Crystallogr D Biol Crystallogr (2001) 57, 361-368. PubMed  Europe PubMed DOI  S
    21. 1999
  21. [YEAR:19-8-1999]Healy,V., O'Connell,J., McCarthy,T.V. and Doonan,S.<br>The lysine-specific proteinase from Armillaria mellea is a member of a novel class of metalloendopeptidases located in basidiomycetes<br>Biochem Biophys Res Commun (19-8-1999) 262, 60-63. PubMed  Europe PubMed DOI
    22. 1998
  22. Nonaka,T., Hashimoto,Y. and Takio,K.<br>Kinetic characterization of lysine-specific metalloendopeptidases from Grifola frondosa and Pleurotus ostreatus fruiting bodies<br>J Biochem (1998) 124, 157-162. PubMed  Europe PubMed  A
    23. 1997
  23. [YEAR:28-11-1997]Nonaka,T., Dohmae,N., Hashimoto,Y. and Takio,K.<br>Amino acid sequences of metalloendopeptidases specific for acyl-lysine bonds from Grifola frondosa and Pleurotus ostreatus fruiting bodies<br>J Biol Chem (28-11-1997) 272, 30032-30039. PubMed  Europe PubMed DOI
    24. 1995
  24. Nonaka,T., Ishikawa,H., Tsumuraya,Y., Hashimoto,Y., Dohmae,N. and Takio,K.<br>Characterization of a thermostable lysine-specific metalloendopeptidase from the fruiting bodies of a basidiomycete, Grifola frondosa<br>J Biochem (1995) 118, 1014-1020. PubMed  Europe PubMed
    25. 1978
  25. Lewis,W.G., Basford,J.M. and Walton,P.L.<br>Specificity and inhibition studies of Armillaria mellea protease<br>Biochim Biophys Acta (1978) 522, 551-560. PubMed  Europe PubMed
    26. 1975
  26. [YEAR:15-8-1975]Doonan,S. and Fahmy,H.M.<br>Specific enzymic cleavage of polypeptides at cysteine residues<br>Eur J Biochem (15-8-1975) 56, 421-426. PubMed  Europe PubMed
  27. Doonan,S., Doonan,H.J., Hanford,R., Vernon,C.A., Walker,J.M., da Airold,L.P., Bossa,F., Barra,D., Carloni,M., Fasella,P. and Riva,F.<br>The primary structure of aspartate aminotransferase from pig heart muscle. Digestion with a proteinase having specificity for lysine residues<br>Biochem J (1975) 149, 497-506. PubMed  Europe PubMed  PMC  EPMC

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