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Literature for peptidase M35.004: peptidyl-Lys metallopeptidase

Summary Alignment Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: A Assay, S Structure, P Specificity, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Ahmed,U., Ochsenreither,K. and Eisele,T.
    Production and application of peptidyl-lys metalloendopeptidase: advances, challenges, and future perspectives
    Appl Microbiol Biotechnol109, 88-88. PubMed  Europe PubMed DOI
    2. 2024
  2. Ahmed,U., Stadelmann,T., Heid,D., Wurtz,B., Pfannstiel,J., Ochsenreither,K. and Eisele,T.
    A novel, robust peptidyl-lys metalloendopeptidase from Trametes coccinea recombinantly expressed in Komagataella phaffii
    Appl Microbiol Biotechnol108, 103-103. PubMed  Europe PubMed DOI
    3. 2020
  3. Zhao,M., Hao,B., Li,H., Cai,M., Xie,J., Liu,H., Tan,M., Zhai,L. and Yu,Q.
    Peptidyl-Lys metalloendopeptidase (Lys-N) purified from dry fruit of Grifola frondosa demonstrates "mirror" digestion property with lysyl endopeptidase (Lys-C)
    Rapid Commun Mass Spectrom34, e8573-e8573. PubMed  Europe PubMed DOI
    4. 2016
  4. Giansanti,P., Tsiatsiani,L., Low,T.Y. and Heck,A.J.
    Six alternative proteases for mass spectrometry-based proteomics beyond trypsin
    Nat Protoc11, 993-1006. PubMed  Europe PubMed DOI
  5. Odum,A.S., Ostergaard,S., Norby,I., Meldal,M. and Olesen,K.
    Heterologous expression of peptidyl-Lys metallopeptidase of Armillaria mellea and mutagenic analysis of the recombinant peptidase
    J Biochem159, 461-470. PubMed  Europe PubMed DOI  E
  6. Odum,A.S., Ostergaard,S., Norby,I., Meldal,M. and Olesen,K.
    Novel application of peptidyl-Lys metallopeptidase as a C-terminal processing protease
    Protein Pept Lett23, 396-403. PubMed  Europe PubMed  P
    7. 2015
  7. Odum,A.S., Olesen,K., Ostergaard,S., Thim,L., Norby,I. and Meldal,M.
    Substrate specificity profiling of peptidyl-Lys metallopeptidase of Armillaria mellea by FRET based peptide library
    Protein Pept Lett22, 514-524. PubMed  Europe PubMed  P
    8. 2014
  8. Gershon,P.D.
    Cleaved and missed sites for trypsin, Lys-C, and Lys-N can be predicted with high confidence on the basis of sequence context
    J Proteome Res13, 702-709. PubMed  Europe PubMed DOI  P
    9. 2012
  9. Heck,A.J.R.
    Peptidyl-Lys metalloendopeptidase
    [ISSN:978-0-12-407744-7]3, 1266-1270. DOI
    10. 2011
  10. Kishimoto,T., Kondo,J., Takai-Igarashi,T. and Tanaka,H.
    Accurate mass comparison coupled with two endopeptidases enables identification of protein termini
    Proteomics11, 485-489. PubMed  Europe PubMed DOI
    11. 2010
  11. Raijmakers,R., Neerincx,P., Mohammed,S. and Heck,A.J.
    Cleavage specificities of the brother and sister proteases Lys-C and Lys-N
    Chem Commun (Camb)46, 8827-8829. PubMed  Europe PubMed DOI  P
  12. Taouatas,N., Heck,A.J. and Mohammed,S.
    Evaluation of metalloendopeptidase Lys-N protease performance under different sample handling conditions
    J Proteome Res9, 4282-4288. PubMed  Europe PubMed DOI
    13. 2009
  13. Boersema,P.J., Taouatas,N., Altelaar,A.F., Gouw,J.W., Ross,P.L., Pappin,D.J., Heck,A.J. and Mohammed,S.
    Straightforward and de novo peptide sequencing by MALDI-MS/MS using a Lys-N metalloendopeptidase
    Mol Cell Proteomics8, 650-660. PubMed  Europe PubMed DOI
  14. Hohmann,L., Sherwood,C., Eastham,A., Peterson,A., Eng,J.K., Eddes,J.S., Shteynberg,D. and Martin,D.B.
    Proteomic analyses using Grifola frondosa metalloendoprotease Lys-N
    J Proteome Res8, 1415-1422. PubMed  Europe PubMed DOI
    15. 2008
  15. Taouatas,N., Drugan,M.M., Heck,A.J. and Mohammed,S.
    Straightforward ladder sequencing of peptides using a Lys-N metalloendopeptidase
    Nat Methods5, 405-407. PubMed  Europe PubMed DOI
    16. 2005
  16. Rao,K.C., Carruth,R.T. and Miyagi,M.
    Proteolytic 18O labeling by peptidyl-Lys metalloendopeptidase for comparative proteomics
    J Proteome Res4, 507-514. PubMed  Europe PubMed DOI
    17. 2004
  17. Takio,K.
    Peptidyl-Lys metalloendopeptidase
    [ISSN:0-12-079610-4]2, 788-792.  V
    18. 2003
  18. Abe,M. and Seguchi,M.
    Proteases of Maitake (Grifola frondosa) responsible for breakdown of wheat flour dough and their reaction with gluten proteins
    Biosci Biotechnol Biochem67, 2018-2021. PubMed  Europe PubMed DOI
    19. 2002
  19. Saito,T., Dohmae,N., Tsujimoto,M. and Takio,K.
    PCR cloning and heterologous expression of cDNA encoding a peptidyl-Lys metalloendopeptidase precursor of Grifola frondosa
    J Gen Appl Microbiol48, 287-292. PubMed  Europe PubMed DOI
    20. 2001
  20. Hori,T., Kumasaka,T., Yamamoto,M., Nonaka,T., Tanaka,N., Hashimoto,Y., Ueki,T. and Takio,K.
    Structure of a new 'aspzincin' metalloendopeptidase from Grifola frondosa: implications for the catalytic mechanism and substrate specificity based on several different crystal forms
    Acta Crystallogr D Biol Crystallogr57, 361-368. PubMed  Europe PubMed DOI  S
    21. 1999
  21. [YEAR:19-8-1999]Healy,V., O'Connell,J., McCarthy,T.V. and Doonan,S.
    The lysine-specific proteinase from Armillaria mellea is a member of a novel class of metalloendopeptidases located in basidiomycetes
    Biochem Biophys Res Commun262, 60-63. PubMed  Europe PubMed DOI
    22. 1998
  22. Nonaka,T., Hashimoto,Y. and Takio,K.
    Kinetic characterization of lysine-specific metalloendopeptidases from Grifola frondosa and Pleurotus ostreatus fruiting bodies
    J Biochem124, 157-162. PubMed  Europe PubMed  A
    23. 1997
  23. [YEAR:28-11-1997]Nonaka,T., Dohmae,N., Hashimoto,Y. and Takio,K.
    Amino acid sequences of metalloendopeptidases specific for acyl-lysine bonds from Grifola frondosa and Pleurotus ostreatus fruiting bodies
    J Biol Chem272, 30032-30039. PubMed  Europe PubMed DOI
    24. 1995
  24. Nonaka,T., Ishikawa,H., Tsumuraya,Y., Hashimoto,Y., Dohmae,N. and Takio,K.
    Characterization of a thermostable lysine-specific metalloendopeptidase from the fruiting bodies of a basidiomycete, Grifola frondosa
    J Biochem118, 1014-1020. PubMed  Europe PubMed
    25. 1978
  25. Lewis,W.G., Basford,J.M. and Walton,P.L.
    Specificity and inhibition studies of Armillaria mellea protease
    Biochim Biophys Acta522, 551-560. PubMed  Europe PubMed
    26. 1975
  26. Doonan,S., Doonan,H.J., Hanford,R., Vernon,C.A., Walker,J.M., da Airold,L.P., Bossa,F., Barra,D., Carloni,M., Fasella,P. and Riva,F.
    The primary structure of aspartate aminotransferase from pig heart muscle. Digestion with a proteinase having specificity for lysine residues
    Biochem J149, 497-506. PubMed  Europe PubMed
  27. [YEAR:15-8-1975]Doonan,S. and Fahmy,H.M.
    Specific enzymic cleavage of polypeptides at cysteine residues
    Eur J Biochem56, 421-426. PubMed  Europe PubMed

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