Literature for peptidase M24.001: methionyl aminopeptidase 1 (Escherichia-type)

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: A Assay, S Structure, M Mutation, P Specificity, I Inhibitor, K Knockout, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

2024

Tan,R., Hoare,M., Bellomio,P., Broas,S., Camacho,K., Swovick,K., Welle,K.A., Hryhorenko,J.R. and Ghaemmaghami,S. Formylation facilitates the reduction of oxidized initiator methionines Proc Natl Acad Sci U S A (2024) 121, e2403880121-e2403880121. PubMed Europe PubMed DOI

2023

Gamerdinger,M., Jia,M., Schloemer,R., Rabl,L., Jaskolowski,M., Khakzar,K.M., Ulusoy,Z., Wallisch,A., Jomaa,A., Hunaeus,G., Scaiola,A., Diederichs,K., Ban,N. and Deuerling,E. NAC controls cotranslational N-terminal methionine excision in eukaryotes Science (2023) 380, 1238-1243. PubMed Europe PubMed DOI
Zhang,M., He,S., Han,X., Cui,J., Wang,H., Huo,X., Yan,F., Feng,L., Wang,C. and Ma,X. Discovery of Potential Antituberculosis Agents Targeted Methionine Aminopeptidase 1 of Mycobacterium tuberculosis by the Developed Fluorescent Probe Anal Chem (2023) 95, 16210-16215. PubMed Europe PubMed DOI

2022

Juhas,M., Pallabothula,V.S.K., Grabrijan,K., Simovicova,M., Jandourek,O., Konecna,K., Barta,P., Paterova,P., Gobec,S., Sosic,I. and Zitko,J. Design, synthesis and biological evaluation of substituted 3-amino-N-(thiazol-2-yl)pyrazine-2-carboxamides as inhibitors of mycobacterial methionine aminopeptidase 1 Bioorg Chem (2022) 118, 105489-105489. PubMed Europe PubMed DOI
Pasquini,M., Grosjean,N., Hixson,K.K., Nicora,C.D., Yee,E.F., Lipton,M., Blaby,I.K., Haley,J.D. and Blaby-Haas,C.E. Zng1 is a GTP-dependent zinc transferase needed for activation of methionine aminopeptidase Cell Rep (2022) 39, 110834-110834. PubMed Europe PubMed DOI

2021

Bala,S., Yellamanda,K.V., Kadari,A., Ravinuthala,V.S.U., Kattula,B., Singh,O.V., Gundla,R. and Addlagatta,A. Selective inhibition of Helicobacter pylori methionine aminopeptidase by azaindole hydroxamic acid derivatives: Design, synthesis, in vitro biochemical and structural studies Bioorg Chem (2021) 115, 105185-105185. PubMed Europe PubMed DOI K I

2020

Boucherit,H., Chikhi,A., Bensegueni,A., Merzoug,A. and Bolla,J.M. Identification of novel inhibitors of bacterial methionine aminopeptidase using in silico virtual screening approach and in vitro validation Curr Comput Aided Drug Des (2020) 16, 389-401. PubMed Europe PubMed DOI I
Ekpenyong,O., Gao,X., Ma,J., Cooper,C., Nguyen,L., Olaleye,O.A., Liang,D. and Xie,H. Pre-clinical pharmacokinetics, tissue distribution and physicochemical studies of CLBQ14, a novel methionine aminopeptidase inhibitor for the treatment of infectious diseases Drug Des Devel Ther (2020) 14, 1263-1277. PubMed Europe PubMed DOI PMC EPMC I
Rodriguez,F., John,S.F., Iniguez,E., Montalvo,S., Michael,K., White,L., Liang,D., Olaleye,O.A. and Maldonado,R.A. In vitro and in vivo characterization of potent antileishmanial methionine aminopeptidase-1 inhibitors Antimicrob Agents Chemother (2020) 64, e01422-19-e01422-19. PubMed Europe PubMed DOI I

2019

Bhat,S.Y., Jagruthi,P., Srinivas,A., Arifuddin,M. and Qureshi,I.A. Synthesis and characterization of quinoline-carbaldehyde derivatives as novel inhibitors for leishmanial methionine aminopeptidase 1 Eur J Med Chem (2019) 186, 111860-111860. PubMed Europe PubMed DOI I
Labrie,S.J., Mosterd,C., Loignon,S., Dupuis,M.E., Desjardins,P., Rousseau,G.M., Tremblay,D.M., Romero,D.A., Horvath,P., Fremaux,C. and Moineau,S. A mutation in the methionine aminopeptidase gene provides phage resistance in Streptococcus thermophilus Sci Rep (2019) 9, 13816-13816. PubMed Europe PubMed DOI M
Vanunu,M., Schall,P., Reingewertz,T.H., Chakraborti,P.K., Grimm,B. and Barkan,D. MapB Protein is the essential methionine aminopeptidase in Mycobacterium tuberculosis Cells (2019) 8, 393-393. PubMed Europe PubMed DOI

2018

Arif,A., Mohammed,K. and Nadeem,M.S. Biochemical and in silico evaluation of recombinant E. coli aminopeptidase and in vitro processed human interferon alpha-2b Turk J Biol (2018) 42, 240-249. PubMed Europe PubMed DOI PMC EPMC E
Ekpenyong,O., Cooper,C., Ma,J., Liang,D., Olaleye,O. and Xie,H. A simple, sensitive and reliable LC-MS/MS method for the determination of 7-bromo-5-chloroquinolin-8-ol (CLBQ14), a potent and selective inhibitor of methionine aminopeptidases: application to pharmacokinetic studies J Chromatogr B Analyt Technol Biomed Life Sci (2018) 1097-1098, 35-43. PubMed Europe PubMed DOI PMC EPMC I
Helgren,T.R., Seven,E.S., Chen,C., Edwards,T.E., Staker,B.L., Abendroth,J., Myler,P.J., Horn,J.R. and Hagen,T.J. The identification of inhibitory compounds of Rickettsia prowazekii methionine aminopeptidase for antibacterial applications Bioorg Med Chem Lett (2018) 28, 1376-1380. PubMed Europe PubMed DOI I

2017

Helgren,T.R., Chen,C., Wangtrakuldee,P., Edwards,T.E., Staker,B.L., Abendroth,J., Sankaran,B., Housley,N.A., Myler,P.J., Audia,J.P., Horn,J.R. and Hagen,T.J. Rickettsia prowazekii methionine aminopeptidase as a promising target for the development of antibacterial agents Bioorg Med Chem (2017) 25, 813-824. PubMed Europe PubMed DOI S I

2016

Helgren,T.R., Wangtrakuldee,P., Staker,B.L. and Hagen,T.J. Advances in bacterial methionine aminopeptidase inhibition Curr Top Med Chem (2016) 16, 397-414. PubMed Europe PubMed S I
Reddi,R., Singarapu,K.K., Pal,D. and Addlagatta,A. The unique functional role of the C-HS hydrogen bond in the substrate specificity and enzyme catalysis of type 1 methionine aminopeptidase Mol Biosyst (2016) 12, 2408-2416. PubMed Europe PubMed DOI

2015

Rose,J.A., Lahiri,S.D., McKinney,D.C., Albert,R., Morningstar,M.L., Shapiro,A.B., Fisher,S.L. and Fleming,P.R. Novel broad-spectrum inhibitors of bacterial methionine aminopeptidase Bioorg Med Chem Lett (2015) 25, 3301-3306. PubMed Europe PubMed DOI I

2014

Altmeyer,M., Amtmann,E., Heyl,C., Marschner,A., Scheidig,A.J. and Klein,C.D. Beta-aminoketones as prodrugs for selective irreversible inhibitors of type-1 methionine aminopeptidases Bioorg Med Chem Lett (2014) 24, 5310-5314. PubMed Europe PubMed DOI I

2013

Arya,T., Kishor,C., Saddanapu,V., Reddi,R. and Addlagatta,A. Discovery of a new genetic variant of methionine aminopeptidase from streptococci with possible post-translational modifications: biochemical and structural characterization PLoS ONE (2013) 8, e75207-e75207. PubMed Europe PubMed DOI PMC EPMC S
Bonissone,S., Gupta,N., Romine,M., Bradshaw,R.A. and Pevzner,P.A. N-terminal protein processing: a comparative proteogenomic analysis Mol Cell Proteomics (2013) 12, 14-28. PubMed Europe PubMed
Wangtrakuldee,P., Byrd,M.S., Campos,C.G., Henderson,M.W., Zhang,Z., Clare,M., Masoudi,A., Myler,P.J., Horn,J.R., Cotter,P.A. and Hagen,T.J. Discovery of inhibitors of Burkholderia pseudomallei methionine aminopeptidase with antibacterial activity ACS Med Chem Lett (2013) 4, 699-703. PubMed Europe PubMed DOI PMC EPMC I

2012

Huguet,F., Melet,A., Alves de Sousa,R., Lieutaud,A., Chevalier,J., Maigre,L., Deschamps,P., Tomas,A., Leulliot,N., Pages,J.M. and Artaud,I. Hydroxamic acids as potent inhibitors of Fe(II) and Mn(II) E. coli methionine aminopeptidase: biological activities and X-ray structures of oxazole hydroxamate-EcMetAP-Mn complexes ChemMedChem (2012) 7, 1020-1030. PubMed Europe PubMed DOI I
Kishor,C., Gumpena,R., Reddi,R. and Addlagatta,A. Structural studies of Enterococcus faecalis methionine aminopeptidase and design of microbe specific 2,2 '-bipyridine based inhibitors MedChemComm (2012) 3, 1406-1412. DOI S I
Kratky,M., Vinsova,J., Novotna,E., Mandikova,J., Wsol,V., Trejtnar,F., Ulmann,V., Stolarikova,J., Fernandes,S., Bhat,S. and Liu,J.O. Salicylanilide derivatives block Mycobacterium tuberculosis through inhibition of isocitrate lyase and methionine aminopeptidase Tuberculosis (Edinb) (2012) 92, 434-439. PubMed Europe PubMed DOI I
Lu,J.P., Yuan,X.H. and Ye,Q.Z. Structural analysis of inhibition of Mycobacterium tuberculosis methionine aminopeptidase by bengamide derivatives Eur J Med Chem (2012) 47, 479-484. PubMed Europe PubMed DOI S I
Sule,N., Singh,R.K., Zhao,P. and Srivastava,D.K. Probing the metal ion selectivity in methionine aminopeptidase via changes in the luminescence properties of the enzyme bound europium ion J Inorg Biochem (2012) 106, 84-89. PubMed Europe PubMed DOI
Walker,K.W. and Bradshaw,R.A. Methionyl aminopeptidase type 1 [ISSN:978-0-12-407743-0] (2012) 3, 1495-1500. DOI

2011

Chai,S.C., Wang,W.L., Ding,D.R. and Ye,Q.Z. Growth inhibition of Escherichia coli and methicillin-resistant Staphylococcus aureus by targeting cellular methionine aminopeptidase Eur J Med Chem (2011) 46, 3537-3540. PubMed Europe PubMed DOI I
Kanudia,P., Mittal,M., Kumaran,S. and Chakraborti,P.K. Amino-terminal extension present in the methionine aminopeptidase type 1c of Mycobacterium tuberculosis is indispensible for its activity BMC Biochem (2011) 12, 35-35. PubMed Europe PubMed DOI
Olaleye,O., Raghunand,T.R., Bhat,S., Chong,C., Gu,P., Zhou,J., Zhang,Y., Bishai,W.R. and Liu,J.O. Characterization of clioquinol and analogues as novel inhibitors of methionine aminopeptidases from Mycobacterium tuberculosis Tuberculosis (Edinb) (2011) 91 Suppl 1, S61-S65. PubMed Europe PubMed DOI I
Shapiro,A.B., Gao,N., Thresher,J., Walkup,G.K. and Whiteaker,J. A high-throughput absorbance-based assay for methionine produced by methionine aminopeptidase using S-adenosyl-L-methionine synthetase J Biomol Screen (2011) 16, 494-505. PubMed Europe PubMed DOI A
Wang,W.L., Chai,S.C. and Ye,Q.Z. Synthesis and biological evaluation of salicylate-based compounds as a novel class of methionine aminopeptidase inhibitors Bioorg Med Chem Lett (2011) 21, 7151-7154. PubMed Europe PubMed DOI I

2010

Altmeyer,M.A., Marschner,A., Schiffmann,R. and Klein,C.D. Subtype-selectivity of metal-dependent methionine aminopeptidase inhibitors Bioorg Med Chem Lett (2010) 20, 4038-4044. PubMed Europe PubMed DOI I
Lu,J.P., Chai,S.C. and Ye,Q.Z. Catalysis and inhibition of Mycobacterium tuberculosis methionine aminopeptidase J Med Chem (2010) 53, 1329-1337. PubMed Europe PubMed DOI S I
Lu,J.P. and Ye,Q.Z. Expression and characterization of Mycobacterium tuberculosis methionine aminopeptidase type 1a Bioorg Med Chem Lett (2010) 20, 2776-2779. PubMed Europe PubMed DOI

2009

Chai,S.C. and Ye,Q.Z. Metal-mediated inhibition is a viable approach for inhibiting cellular methionine aminopeptidase Bioorg Med Chem Lett (2009) 19, 6862-6864. PubMed Europe PubMed DOI I
Chai,S.C., Lu,J.P. and Ye,Q.Z. Determination of binding affinity of metal cofactor to the active site of methionine aminopeptidase based on quantitation of functional enzyme Anal Biochem (2009) 395, 263-264. PubMed Europe PubMed DOI PMC EPMC
Chai,S.C. and Ye,Q.Z. Analysis of the stoichiometric metal activation of methionine aminopeptidase BMC Biochem (2009) 10, 32-32. PubMed Europe PubMed DOI
Drath,M., Baier,K. and Forchhammer,K. An alternative methionine aminopeptidase, MAP-A, is required for nitrogen starvation and high-light acclimation in the cyanobacterium Synechocystis sp. PCC 6803 Microbiology (Reading) (2009) 155, 1427-1439. PubMed Europe PubMed DOI
Mitra,S., Bennett,B. and Holz,R.C. Mutation of H63 and its catalytic affect on the methionine aminopeptidase from Escherichia coli Biochim Biophys Acta (2009) 1794, 137-143. PubMed Europe PubMed DOI PMC EPMC
Mitra,S., Sheppard,G., Wang,J., Bennett,B. and Holz,R.C. Analyzing the binding of Co(II)-specific inhibitors to the methionyl aminopeptidases from Escherichia coli and Pyrococcus furiosus J Biol Inorg Chem (2009) 14, 573-585. PubMed Europe PubMed DOI PMC EPMC I
Wang,W.L., Chai,S.C. and Ye,Q.Z. Synthesis and structure-function analysis of Fe(II)-form-selective antibacterial inhibitors of Escherichia coli methionine aminopeptidase Bioorg Med Chem Lett (2009) 19, 1080-1083. PubMed Europe PubMed DOI PMC EPMC I

2008

Chai,S.C., Wang,W.L. and Ye,Q.Z. Fe(II) is the native cofactor for Escherichia coli methionine aminopeptidase J Biol Chem (2008) 283, 26879-26885. PubMed Europe PubMed DOI PMC EPMC
Haldar,M.K., Scott,M.D., Sule,N., Srivastava,D.K. and Mallik,S. Synthesis of barbiturate-based methionine aminopeptidase-1 inhibitors Bioorg Med Chem Lett (2008) 18, 2373-2376. PubMed Europe PubMed DOI PMC EPMC I
Larrabee,J.A., Chyun,S.A. and Volwiler,A.S. Magnetic circular dichroism study of a dicobalt(II) methionine aminopeptidase/fumagillin complex and dicobalt II-II and II-III model complexes Inorg Chem (2008) 47, 10499-10508. PubMed Europe PubMed DOI
Mitra,S., Job,K.M., Meng,L., Bennett,B. and Holz,R.C. Analyzing the catalytic role of Asp97 in the methionine aminopeptidase from Escherichia coli FEBS J (2008) 275, 6248-6259. PubMed Europe PubMed DOI PMC EPMC
Narayanan,S.S., Ramanujan,A., Krishna,S. and Nampoothiri,K.M. Purification and biochemical characterization of methionine aminopeptidase (MetAP) from Mycobacterium smegmatis mc2155 Appl Biochem Biotechnol (2008) 151, 512-521. PubMed Europe PubMed DOI
Vedantham,P., Zhang,M., Gor,P.J., Huang,M., Georg,G.I., Lushington,G.H., Mitscher,L.A., Ye,Q.Z. and Hanson,P.R. Studies towards the synthesis of methionine aminopeptidase inhibitors: diversification utilizing a ROMP-derived coupling reagent J Comb Chem (2008) 10, 195-203. PubMed Europe PubMed DOI I
Vedantham,P., Guerra,J.M., Schoenen,F., Huang,M., Gor,P.J., Georg,G.I., Wang,J.L., Neuenswander,B., Lushington,G.H., Mitscher,L.A., Ye,Q.Z. and Hanson,P.R. Ionic immobilization, diversification, and release: application to the generation of a library of methionine aminopeptidase inhibitors J Comb Chem (2008) 10, 185-194. PubMed Europe PubMed DOI I
Wang,W.L., Chai,S.C., Huang,M., He,H.Z., Hurley,T.D. and Ye,Q.Z. Discovery of inhibitors of Escherichia coli methionine aminopeptidase with the Fe(II)-form selectivity and antibacterial activity J Med Chem (2008) 51, 6110-6120. PubMed Europe PubMed DOI PMC EPMC I
Watterson,S.J., Mitra,S., Swierczek,S.I., Bennett,B. and Holz,R.C. Kinetic and spectroscopic analysis of the catalytic role of H79 in the methionine aminopeptidase from Escherichia coli Biochemistry (2008) 47, 11885-11893. PubMed Europe PubMed DOI PMC EPMC

2007

Evdokimov,A.G., Pokross,M., Walter,R.L., Mekel,M., Barnett,B.L., Amburgey,J., Seibel,W.L., Soper,S.J., Djung,J.F., Fairweather,N., Diven,C., Rastogi,V., Grinius,L., Klanke,C., Siehnel,R., Twinem,T., Andrews,R. and Curnow,A. Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors Proteins (2007) 66, 538-546. PubMed Europe PubMed DOI S I
Huang,M., Xie,S.X., Ma,Z.Q., Huang,Q.Q., Nan,F.J. and Ye,Q.Z. Inhibition of monometalated methionine aminopeptidase: inhibitor discovery and crystallographic analysis J Med Chem (2007) 50, 5735-5742. PubMed Europe PubMed DOI PMC EPMC S I
Leopoldini,M., Russo,N. and Toscano,M. Which one among Zn(II), Co(II), Mn(II), and Fe(II) is the most efficient ion for the methionine aminopeptidase catalyzed reaction? J Am Chem Soc (2007) 129, 7776-7784. PubMed Europe PubMed DOI
Ma,Z.Q., Xie,S.X., Huang,Q.Q., Nan,F.J., Hurley,T.D. and Ye,Q.Z. Structural analysis of inhibition of E. coli methionine aminopeptidase: implication of loop adaptability in selective inhibition of bacterial enzymes BMC Struct Biol (2007) 7, 84-84. PubMed Europe PubMed DOI PMC EPMC S I
Qiu,W.W., Xu,J., Li,J.Y., Li,J. and Nan,F.J. Activity-based protein profiling for type I methionine aminopeptidase by using photo-affinity trimodular probes Chembiochem (2007) 8, 1351-1358. PubMed Europe PubMed DOI

2006

Frottin,F., Martinez,A., Peynot,P., Mitra,S., Holz,R.C., Giglione,C. and Meinnel,T. The proteomics of N-terminal methionine cleavage Mol Cell Proteomics (2006) 5, 2336-2349. PubMed Europe PubMed DOI P
Xie,S.X., Huang,W.J., Ma,Z.Q., Huang,M., Hanzlik,R.P. and Ye,Q.Z. Structural analysis of metalloform-selective inhibition of methionine aminopeptidase Acta Crystallogr D Biol Crystallogr (2006) 62, 425-432. PubMed Europe PubMed DOI S I
Ye,Q.Z., Xie,S.X., Ma,Z.Q., Huang,M. and Hanzlik,R.P. Structural basis of catalysis by monometalated methionine aminopeptidase Proc Natl Acad Sci U S A (2006) 103, 9470-9475. PubMed Europe PubMed DOI PMC EPMC S

2005

Addlagatta,A., Quillin,M.L., Omotoso,O., Liu,J.O. and Matthews,B.W. Identification of an SH3-binding motif in a new class of methionine aminopeptidases from Mycobacterium tuberculosis suggests a mode of interaction with the ribosome Biochemistry (2005) 44, 7166-7174. PubMed Europe PubMed DOI S

2004

Bradshaw,R.A., Yi,E. and Walker,K.W. Methionyl aminopeptidase type I [ISSN:0-12-079610-4] (2004) 2, 911-917. V
Giglione,C., Boularot,A. and Meinnel,T. Protein N-terminal methionine excision Cell Mol Life Sci (2004) 61, 1455-1474. PubMed Europe PubMed DOI
[YEAR:5-1-2004]Hu,X., Zhu,J., Srivathsan,S. and Pei,D. Peptidyl hydroxamic acids as methionine aminopeptidase inhibitors Bioorg Med Chem Lett (5-1-2004) 14, 77-79. PubMed Europe PubMed DOI I
[YEAR:6-10-2004]Larrabee,J.A., Leung,C.H., Moore,R.L., Thamrong-nawasawat,T. and Wessler,B.S. Magnetic circular dichroism and cobalt(II) binding equilibrium studies of Escherichia coli methionyl aminopeptidase J Am Chem Soc (6-10-2004) 126, 12316-12324. PubMed Europe PubMed DOI
[YEAR:14-5-2004]Li,J.Y., Cui,Y.M., Chen,L.L., Gu,M., Li,J., Nan,F.J. and Ye,Q.Z. Mutations at the S1 sites of methionine aminopeptidases from Escherichia coli and Homo sapiens reveal the residues critical for substrate specificity J Biol Chem (14-5-2004) 279, 21128-21134. PubMed Europe PubMed DOI P
Liao,Y.D., Jeng,J.C., Wang,C.F., Wang,S.C. and Chang,S.T. Removal of N-terminal methionine from recombinant proteins by engineered E. coli methionine aminopeptidase Protein Sci (2004) 13, 1802-1810. PubMed Europe PubMed DOI PMC EPMC
[YEAR:15-6-2004]Liu,L.F., Hsieh,C.H., Liu,P.F., Tsai,S.P. and Tam,M.F. Escherichia coli methionine aminopeptidase with Tyr168 to alanine substitution can improve the N-terminal processing of recombinant proteins with valine at the penultimate position Anal Biochem (15-6-2004) 329, 345-347. PubMed Europe PubMed DOI
[YEAR:1-8-2004]Spraggon,G., Schwarzenbacher,R., Kreusch,A., McMullan,D., Brinen,L.S., Canaves,J.M., Dai,X., Deacon,A.M., Elsliger,M.A., Eshagi,S., Floyd,R., Godzik,A., Grittini,C., Grzechnik,S.K., Jaroszewski,L., Karlak,C., Klock,H.E., Koesema,E., Kovarik,J.S., Kuhn,P., McPhillips,T.M., Miller,M.D., Morse,A., Moy,K., Ouyang,J., Page,R., Quijano,K., Rezezadeh,F., Robb,A., Sims,E., Stevens,R.C., van den Bedem,H., Velasquez,J., Vincent,J., von Delft,F., Wang,X., West,B., Wolf,G., Xu,Q., Hodgson,K.O., Wooley,J., Lesley,S.A. and Wilson,I.A. Crystal structure of a methionine aminopeptidase (TM1478) from Thermotoga maritima at 1.9 A resolution Proteins (1-8-2004) 56, 396-400. PubMed Europe PubMed DOI S
[YEAR:3-11-2004]Ye,Q.Z., Xie,S.X., Huang,M., Huang,W.J., Lu,J.P. and Ma,Z.Q. Metalloform-selective inhibitors of Escherichia coli methionine aminopeptidase and X-ray structure of a Mn(II)-form enzyme complexed with an inhibitor J Am Chem Soc (3-11-2004) 126, 13940-13941. PubMed Europe PubMed DOI S I

2003

Atanassova,A., Sugita,M., Sugiura,M., Pajpanova,T. and Ivanov,I. Molecular cloning, expression and characterization of three distinctive genes encoding methionine aminopeptidases in cyanobacterium Synechocystis sp. strain PCC6803 Arch Microbiol (2003) 180, 185-193. PubMed Europe PubMed DOI
Boufous,e.H. and Vadeboncoeur,C. Purification and characterization of the Streptococcus salivarius methionine aminopeptidase (MetAP) Biochimie (2003) 85, 993-997. PubMed Europe PubMed DOI
[YEAR:27-5-2003]Copik,A.J., Swierczek,S.I., Lowther,W.T., D'souza,V.M., Matthews,B.W. and Holz,R.C. Kinetic and spectroscopic characterization of the H178A methionyl aminopeptidase from Escherichia coli Biochemistry (27-5-2003) 42, 6283-6292. PubMed Europe PubMed DOI
[YEAR:28-11-2003]Klein,C.D., Schiffmann,R., Folkers,G., Piana,S. and Rothlisberger,U. Protonation states of methionine aminopeptidase and their relevance for inhibitor binding and catalytic activity J Biol Chem (28-11-2003) 278, 47862-47867. PubMed Europe PubMed DOI I
[YEAR:18-7-2003]Li,J.Y., Chen,L.L., Cui,Y.M., Luo,Q.L., Li,J., Nan,F.J. and Ye,Q.Z. Specificity for inhibitors of metal-substituted methionine aminopeptidase Biochem Biophys Res Commun (18-7-2003) 307, 172-179. PubMed Europe PubMed DOI I
[YEAR:19-6-2003]Luo,Q.L., Li,J.Y., Liu,Z.Y., Chen,L.L., Li,J., Qian,Z., Shen,Q., Li,Y., Lushington,G.H., Ye,Q.Z. and Nan,F.J. Discovery and structural modification of inhibitors of methionine aminopeptidases from Escherichia coli and Saccharomyces cerevisiae J Med Chem (19-6-2003) 46, 2631-2640. PubMed Europe PubMed DOI I

2002

[YEAR:6-11-2002]Bennett,B., Antholine,W.E., D'souza,V.M., Chen,G., Ustinyuk,L. and Holz,R.C. Structurally distinct active sites in the copper(II)-substituted aminopeptidases from Aeromonas proteolytica and Escherichia coli J Am Chem Soc (6-11-2002) 124, 13025-13034. PubMed Europe PubMed DOI PMC EPMC
[YEAR:29-10-2002]D'souza,V.M., Swierczek,S.I., Cosper,N.J., Meng,L., Ruebush,S., Copik,A.J., Scott,R.A. and Holz,R.C. Kinetic and structural characterization of manganese(II)-loaded methionyl aminopeptidases Biochemistry (29-10-2002) 41, 13096-13105. PubMed Europe PubMed DOI

2001

[YEAR:6-11-2001]Cosper,N.J., D'souza,V.M., Scott,R.A. and Holz,R.C. Structural evidence that the methionyl aminopeptidase from Escherichia coli is a mononuclear metalloprotease Biochemistry (6-11-2001) 40, 13302-13309. PubMed Europe PubMed DOI I

2000

[YEAR:4-4-2000]D'souza,V.M., Bennett,B., Copik,A.J. and Holz,R.C. Divalent metal binding properties of the methionyl aminopeptidase from Escherichia coli Biochemistry (4-4-2000) 39, 3817-3826. PubMed Europe PubMed DOI
Datta,B. MAPs and POEP of the roads from prokaryotic to eukaryotic kingdoms Biochimie (2000) 82, 95-107. PubMed Europe PubMed DOI V
[YEAR:7-3-2000]Lowther,W.T. and Matthews,B.W. Structure and function of the methionine aminopeptidases Biochim Biophys Acta (7-3-2000) 1477, 157-167. PubMed Europe PubMed DOI S I
[YEAR:10-4-2000]Zhou,Y., Guo,X.C., Yi,T., Yoshimoto,T. and Pei,D. Two continuous spectrophotometric assays for methionine aminopeptidase Anal Biochem (10-4-2000) 280, 159-165. PubMed Europe PubMed DOI A

1999

Chiu,C.H., Lee,C.Z., Lin,K.S., Tam,M.F. and Lin,L.Y. Amino acid residues involved in the functional integrity of Escherichia coli methionine aminopeptidase J Bacteriol (1999) 181, 4686-4689. PubMed Europe PubMed PMC EPMC
[YEAR:24-8-1999]D'souza,V.M. and Holz,R.C. The methionyl aminopeptidase from Escherichia coli can function as an iron(II) enzyme Biochemistry (24-8-1999) 38, 11079-11085. PubMed Europe PubMed DOI
[YEAR:10-4-1999]Larrabee,J.A., Thamrong-nawasawat,T. and Mon,S.Y. High-pressure liquid chromatographic method for the assay of methionine aminopeptidase activity: application to the study of enzymatic inactivation Anal Biochem (10-4-1999) 269, 194-198. PubMed Europe PubMed DOI A
[YEAR:15-6-1999]Lowther,W.T., Orville,A.M., Madden,D.T., Lim,S., Rich,D.H. and Matthews,B.W. Escherichia coli methionine aminopeptidase: implications of crystallographic analyses of the native, mutant, and inhibited enzymes for the mechanism of catalysis Biochemistry (15-6-1999) 38, 7678-7688. PubMed Europe PubMed DOI I
[YEAR:9-11-1999]Lowther,W.T., Zhang,Y., Sampson,P.B., Honek,J.F. and Matthews,B.W. Insights into the mechanism of Escherichia coli methionine aminopeptidase from the structural analysis of reaction products and phosphorus-based transition-state analogues Biochemistry (9-11-1999) 38, 14810-14819. PubMed Europe PubMed DOI S I

1998

Keding,S.J., Dales,N.A., Lim,S.J., Beaulieu,D. and Rich,D.H. Synthesis of (3R)-amino-(2S)-hydroxy amino acids for inhibition of methionine aminopeptidase-1 Synthetic Communications (1998) 28, 4463-4470. I
[YEAR:13-10-1998]Lowther,W.T., McMillen,D.A., Orville,A.M. and Matthews,B.W. The anti-angiogenic agent fumagillin covalently modifies a conserved active-site histidine in the Escherichia coli methionine aminopeptidase Proc Natl Acad Sci U S A (13-10-1998) 95, 12153-12157. PubMed Europe PubMed DOI PMC EPMC I

1994

Bazan,J.F., Weaver,L.H., Roderick,S.L., Huber,R. and Matthews,B.W. Sequence and structure comparison suggest that methionine aminopeptidase, prolidase, aminopeptidase P, and creatinase share a common fold Proc Natl Acad Sci U S A (1994) 91, 2473-2477. PubMed Europe PubMed PMC EPMC S

1993

Meinnel,T., Mechulam,Y. and Blanquet,S. Methionine as translation start signal: a review of the enzymes of the pathway in Escherichia coli Biochimie (1993) 75, 1061-1075. PubMed Europe PubMed DOI
Roderick,S.L. and Matthews,B.W. Structure of the cobalt-dependent methionine aminopeptidase from Escherichia coli: a new type of proteolytic enzyme Biochemistry (1993) 32, 3907-3912. PubMed Europe PubMed S

1990

Movva,N.R., Semon,D., Meyer,C., Kawashima,E., Wingfield,P., Miller,J.L. and Miller,C.G. Cloning and nucleotide sequence of the Salmonella typhimurium pepM gene Mol Gen Genet (1990) 223, 345-348. PubMed Europe PubMed

1989

Chang,S.Y., McGary,E.C. and Chang,S. Methionine aminopeptidase gene of Escherichia coli is essential for cell growth J Bacteriol (1989) 171, 4071-4072. PubMed Europe PubMed PMC EPMC
Hirel,P.H., Schmitter,M.J., Dessen,P., Fayat,G. and Blanquet,S. Extent of N-terminal methionine excision from Escherichia coli proteins is governed by the side-chain length of the penultimate amino acid Proc Natl Acad Sci U S A (1989) 86, 8247-8251. PubMed Europe PubMed PMC EPMC
Wingfield,P., Graber,P., Turcatti,G., Movva,N.R., Pelletier,M., Craig,S., Rose,K. and Miller,C.G. Purification and characterization of a methionine-specific aminopeptidase from Salmonella typhimurium Eur J Biochem (1989) 180, 23-32. PubMed Europe PubMed

1988

Roderick,S.L. and Matthews,B.W. Crystallization of methionine aminopeptidase from Escherichia coli J Biol Chem (1988) 263, 16531-16531. PubMed Europe PubMed

1987

Ben-Bassat,A., Bauer,K., Chang,S.Y., Myambo,K., Boosman,A. and Chang,S. Processing of the initiation methionine from proteins: properties of the Escherichia coli methionine aminopeptidase and its gene structure J Bacteriol (1987) 169, 751-757. PubMed Europe PubMed PMC EPMC
Miller,C.G., Strauch,K.L., Kukral,A.M., Miller,J.L., Wingfield,P.T., Mazzei,G.J., Werlen,R.C., Graber,P. and Movva,N.R. N-terminal methionine-specific peptidase in Salmonella typhimurium Proc Natl Acad Sci U S A (1987) 84, 2718-2722. PubMed Europe PubMed PMC EPMC

1985

Sherman,F., Stewart,J.W. and Tsunasawa,S. Methionine or not methionine at the beginning of a protein Bioessays (1985) 3, 27-31. PubMed Europe PubMed DOI P