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Literature for peptidase M16.003: mitochondrial processing peptidase beta-subunit

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, M Mutation, P Specificity, I Inhibitor, L Localization, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Bayne,A.N., Simons,D.M., Soya,N., Grenier,K., Lukacs,G.L., Fon,E.A. and Trempe,J.F.<br>Substrate recognition by the human mitochondrial processing peptidase and its processing of PINK1<br>J Biol Chem (2025) , 110860-110860. PubMed  Europe PubMed DOI
  2. Erdinc,D., Albus,C.A., Rodriguez-Luis,A., Menger,K.E., Thorsell,A., Atanassov,I., Rovsnik,U., Falkenberg,M., Gustafsson,C.M. and Nicholls,T.J.J.<br>Proteolytic cleavage activates the mitochondrial isoform of TOP3A<br>Nucleic Acids Res (2025) 53 PubMed  Europe PubMed DOI  PMC  EPMC
  3. Ludwig,K. and Heidorn-Czarna,M.<br>Mitochondrial Proteases and Their Roles in Mitophagy in Plants, Animals, and Yeast<br>Plant Cell Physiol (2025) PubMed  Europe PubMed DOI  V
    4. 2024
  4. Kucukkose,C., Vogtle,F.N. and Flotho,A.<br>Monitoring mitochondrial precursor processing and presequence peptide degradation<br>Methods Enzymol (2024) 706, 193-213. PubMed  Europe PubMed DOI
    5. 2023
  5. Bayne,A.N., Dong,J., Amiri,S., Farhan,S.M.K. and Trempe,J.F.<br>MTSviewer: A database to visualize mitochondrial targeting sequences, cleavage sites, and mutations on protein structures<br>PLoS ONE (2023) 18, e0284541-e0284541. PubMed  Europe PubMed DOI  PMC  EPMC
  6. Moe,A., Dimogkioka,A.R., Rapaport,D., Ojemyr,L.N. and Brzezinski,P.<br>Structure and function of the S. pombe III-IV-cyt c supercomplex<br>Proc Natl Acad Sci U S A (2023) 120, e2307697120-e2307697120. PubMed  Europe PubMed DOI  PMC  EPMC
    7. 2022
  7. Heidorn-Czarna,M., Maziak,A. and Janska,H.<br>Protein Processing in Plant Mitochondria Compared to Yeast and Mammals<br>Front Plant Sci (2022) 13, 824080-824080. PubMed  Europe PubMed DOI  PMC  EPMC  V
    8. 2021
  8. Sim,J., Park,J., Woo,H.A. and Rhee,S.G.<br>Maturation of Mitochondrially Targeted Prx V Involves a Second Cleavage by Mitochondrial Intermediate Peptidase That Is Sensitive to Inhibition by H2O2<br>Antioxidants (Basel) (2021) 10 PubMed  Europe PubMed DOI  PMC  EPMC
    9. 2020
  9. Xiang,N., Guo,C., Liu,J., Xu,H., Dixon,R., Yang,J. and Wang,Y.P.<br>Using synthetic biology to overcome barriers to stable expression of nitrogenase in eukaryotic organelles<br>Proc Natl Acad Sci U S A (2020) 117, 16537-16545. PubMed  Europe PubMed DOI  PMC  EPMC
    10. 2019
  10. Lhouvum,K., Balaji,S.N., Ahsan,M.J. and Trivedi,V.<br>Plasmodium falciparum PFI1625c offers an opportunity to design potent anti-malarials: biochemical characterization and testing potentials in drug discovery<br>Acta Trop (2019) 191, 116-127. PubMed  Europe PubMed DOI  I
    11. 2018
  11. Vogtle,F.N., Brandl,B., Larson,A., Pendziwiat,M., Friederich,M.W., White,S.M., Basinger,A., Kucukkose,C., Muhle,H., Jahn,J.A., Keminer,O., Helbig,K.L., Delto,C.F., Myketin,L., Mossmann,D., Burger,N., Miyake,N., Burnett,A., van Baalen,A., Lovell,M.A., Matsumoto,N., Walsh,M., Yu,H.C., Shinde,D.N., Stephani,U., Van Hove,J.L.K., Muller,F.J. and Helbig,I.<br>Mutations in PMPCB encoding the catalytic subunit of the mitochondrial presequence protease cause neurodegeneration in early childhood<br>Am J Hum Genet (2018) 102, 557-573. PubMed  Europe PubMed DOI  M
    12. 2016
  12. Dasari,S. and Kolling,R.<br>Role of mitochondrial processing peptidase and AAA proteases in processing of the yeast acetohydroxyacid synthase precursor<br>FEBS Open Bio (2016) 6, 765-773. PubMed  Europe PubMed DOI  PMC  EPMC  M
    13. 2015
  13. Burkhart,J.M., Taskin,A.A., Zahedi,R.P. and Vogtle,F.N.<br>Quantitative profiling for substrates of the mitochondrial presequence processing protease reveals a set of nonsubstrate proteins increased upon proteotoxic stress<br>J Proteome Res (2015) 14, 4550-4563. PubMed  Europe PubMed DOI  P
    14. 2014
  14. Pandey,D., Bhunia,A., Oh,Y.J., Chang,F., Bergman,Y., Kim,J.H., Serbo,J., Boronina,T.N., Cole,R.N., Van Eyk,J., Remaley,A.T., Berkowitz,D.E. and Romer,L.H.<br>OxLDL triggers retrograde translocation of arginase2 in aortic endothelial cells via ROCK and mitochondrial processing peptidase<br>Circ Res (2014) 115, 450-459. PubMed  Europe PubMed DOI
    15. 2013
  15. Kucera,T., Otyepka,M., Matuskova,A., Samad,A., Kutejova,E. and Janata,J.<br>A computational study of the glycine-rich loop of mitochondrial processing peptidase<br>PLoS ONE (2013) 8, e74518-e74518. PubMed  Europe PubMed DOI  PMC  EPMC
  16. Mach,J., Poliak,P., Matuskova,A., Zarsky,V., Janata,J., Lukes,J. and Tachezy,J.<br>An advanced system of the mitochondrial processing peptidase and core protein family in Trypanosoma brucei and multiple origins of the core I subunit in eukaryotes<br>Genome Biol Evol (2013) 5, 860-875. PubMed  Europe PubMed DOI
  17. Teixeira,P.F. and Glaser,E.<br>Processing peptidases in mitochondria and chloroplasts<br>Biochim Biophys Acta (2013) 1833, 360-370. PubMed  Europe PubMed DOI  V
    18. 2012
  18. Desy,S., Schneider,A. and Mani,J.<br>Trypanosoma brucei has a canonical mitochondrial processing peptidase<br>Mol Biochem Parasitol (2012) 185, 161-164. PubMed  Europe PubMed DOI
  19. Greene,A.W., Grenier,K., Aguileta,M.A., Muise,S., Farazifard,R., Haque,M.E., McBride,H.M., Park,D.S. and Fon,E.A.<br>Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment<br>EMBO Rep (2012) 13, 378-385. PubMed  Europe PubMed DOI
  20. Kmiec,B., Urantowka,A., Lech,M. and Janska,H.<br>Two-step processing of AtFtsH4 precursor by mitochondrial processing peptidase in Arabidopsis thaliana<br>Mol Plant (2012) 5, 1417-1419. PubMed  Europe PubMed DOI
  21. Kutejova,E., Kucera,T., Matuskova,A. and Janata,J.<br>Mitochondrial processing peptidase<br>[ISSN:978-0-12-407744-7] (2012) 3, 1435-1442. DOI
  22. Mossmann,D., Meisinger,C. and Vogtle,F.N.<br>Processing of mitochondrial presequences<br>Biochim Biophys Acta (2012) 1819, 1098-1106. PubMed  Europe PubMed DOI  V
    23. 2011
  23. Amata,O., Marino,T., Russo,N. and Toscano,M.<br>A proposal for mitochondrial processing peptidase catalytic mechanism<br>J Am Chem Soc (2011) 133, 17824-17831. PubMed  Europe PubMed DOI
    24. 2010
  24. Dvorakova-Hola,K., Matuskova,A., Kubala,M., Otyepka,M., Kucera,T., Vecer,J., Herman,P., Parkhomenko,N., Kutejova,E. and Janata,J.<br>Glycine-rich loop of mitochondrial processing peptidase alpha-subunit is responsible for substrate recognition by a mechanism analogous to mitochondrial receptor Tom20<br>J Mol Biol (2010) 396, 1197-1210. PubMed  Europe PubMed DOI
  25. Porras,P., McDonagh,B., Pedrajas,J.R., Barcena,J.A. and Padilla,C.A.<br>Structure and function of yeast glutaredoxin 2 depend on postranslational processing and are related to subcellular distribution<br>Biochim Biophys Acta (2010) 1804, 839-845. PubMed  Europe PubMed DOI  P
    26. 2009
  26. Carrie,C., Giraud,E. and Whelan,J.<br>Protein transport in organelles: dual targeting of proteins to mitochondria and chloroplasts<br>FEBS J (2009) 276, 1187-1195. PubMed  Europe PubMed DOI
    27. 2008
  27. Nagayama,K., Itono,S., Yoshida,T., Ishiguro,S., Ochiai,H. and Ohmachi,T.<br>Antisense RNA inhibition of the beta subunit of the Dictyostelium discoideum mitochondrial processing peptidase induces the expression of mitochondrial proteins<br>Biosci Biotechnol Biochem (2008) 72, 1836-1846. PubMed  Europe PubMed DOI
  28. Schmucker,S., Argentini,M., Carelle-Calmels,N., Martelli,A. and Puccio,H.<br>The in vivo mitochondrial two-step maturation of human frataxin<br>Hum Mol Genet (2008) 17, 3521-3531. PubMed  Europe PubMed DOI
  29. Smid,O., Matuskova,A., Harris,S.R., Kucera,T., Novotny,M., Horvathova,L., Hrdy,I., Kutejova,E., Hirt,R.P., Embley,T.M., Janata,J. and Tachezy,J.<br>Reductive evolution of the mitochondrial processing peptidases of the unicellular parasites Trichomonas vaginalis and Giardia intestinalis<br>PLoS Pathog (2008) 4, e1000243-e1000243. PubMed  Europe PubMed DOI  PMC  EPMC
    30. 2007
  30. Mukhopadhyay,A., Yang,C.S., Wei,B. and Weiner,H.<br>Precursor protein is readily degraded in mitochondrial matrix space if the leader is not processed by mitochondrial processing peptidase<br>J Biol Chem (2007) 282, 37266-37275. PubMed  Europe PubMed DOI
  31. Nishino,T.G., Kitano,K., Kojima,K., Ogishima,T., Ito,A. and Kitada,S.<br>Spatial orientation of mitochondrial processing peptidase and a preprotein revealed by fluorescence resonance energy transfer<br>J Biochem (2007) 141, 889-895. PubMed  Europe PubMed DOI  L
    32. 2006
  32. Khalimonchuk,O., Ott,M., Funes,S., Ostermann,K., Rodel,G. and Herrmann,J.M.<br>Sequential processing of a mitochondrial tandem protein: insights into protein import in Schizosaccharomyces pombe<br>Eukaryot Cell (2006) 5, 997-1006. PubMed  Europe PubMed DOI  PMC  EPMC
    33. 2005
  33. [YEAR:1-10-2005]Oshima,T., Yamasaki,E., Ogishima,T., Kadowaki,K., Ito,A. and Kitada,S.<br>Recognition and processing of a nuclear-encoded polyprotein precursor by mitochondrial processing peptidase<br>Biochem J (1-10-2005) 385, 755-761. PubMed  Europe PubMed DOI  PMC  EPMC
    34. 2004
  34. Braun,H.P. and Schmitz,U.K.<br>Mitochondrial processing peptidase<br>[ISSN:0-12-079610-4] (2004) 2, 882-886.  V
  35. Janata,J., Hola,K., Kubala,M., Gakh,O., Parkhomenko,N., Matuskova,A., Kutejova,E. and Amler,E.<br>Substrate evokes translocation of both domains in the mitochondrial processing peptidase alpha-subunit during which the C-terminus acts as a stabilizing element<br>Biochem Biophys Res Commun (2004) 316, 211-217. PubMed  Europe PubMed DOI
  36. Rudhe,C., Clifton,R., Chew,O., Zemam,K., Richter,S., Lamppa,G., Whelan,J. and Glaser,E.<br>Processing of the dual targeted precursor protein of glutathione reductase in mitochondria and chloroplasts<br>J Mol Biol (2004) 343, 639-647. PubMed  Europe PubMed DOI
    37. 2003
  37. [YEAR:17-1-2003]Kitada,S., Yamasaki,E., Kojima,K. and Ito,A.<br>Determination of the cleavage site of the presequence by mitochondrial processing peptidase on the substrate binding scaffold and the multiple subsites inside a molecular cavity<br>J Biol Chem (17-1-2003) 278, 1879-1885. PubMed  Europe PubMed DOI
    38. 2002
  38. [YEAR:2-9-2002]Gakh,O., Cavadini,P. and Isaya,G.<br>Mitochondrial processing peptidases<br>Biochim Biophys Acta (2-9-2002) 1592, 63-77. PubMed  Europe PubMed DOI
  39. Mukhopadhyay,A., Hammen,P., Waltner-Law,M. and Weiner,H.<br>Timing and structural consideration for the processing of mitochondrial matrix space proteins by the mitochondrial processing peptidase (MPP)<br>Protein Sci (2002) 11, 1026-1035. PubMed  Europe PubMed DOI  PMC  EPMC
    40. 2001
  40. [YEAR:2-3-2001]Deng,K., Shenoy,S.K., Tso,S.C., Yu,L. and Yu,C.A.<br>Reconstitution of mitochondrial processing peptidase from the core proteins (subunits I and II) of bovine heart mitochondrial cytochrome bc(1) complex<br>J Biol Chem (2-3-2001) 276, 6499-6505. PubMed  Europe PubMed DOI
  41. [YEAR:15-1-2001]Gakh,O., Obsil,T., Adamec,J., Spizek,J., Amler,E., Janata,J. and Kalousek,F.<br>Substrate binding changes conformation of the alpha-, but not the beta-subunit of mitochondrial processing peptidase<br>Arch Biochem Biophys (15-1-2001) 385, 392-396. PubMed  Europe PubMed DOI
  42. [YEAR:1-2-2001]Gordon,D.M., Kogan,M., Knight,S.A.B., Dancis,A. and Pain,D.<br>Distinct roles for two N-terminal cleaved domains in mitochondrial import of the yeast frataxin homolog, Yfh1p<br>Hum Mol Genet (1-2-2001) 10, 259-269. PubMed  Europe PubMed
  43. Kitada,S. and Ito,A.<br>Electrostatic recognition of matrix targeting signal by mitochondrial processing peptidase<br>J Biochem (2001) 129, 155-161. PubMed  Europe PubMed
  44. [YEAR:28-9-2001]Kitada,S., Kojima,K. and Ito,A.<br>Glu(191) and Asp(195) in rat mitochondrial processing peptidase beta subunit are involved in effective cleavage of precursor protein through interaction with the proximal arginine<br>Biochem Biophys Res Commun (28-9-2001) 287, 594-599. PubMed  Europe PubMed DOI
  45. Kojima,K., Yamasaki,E., Kitada,S., Ogishima,T. and Ito,A.<br>Recognition of mitochondrial protein precursor lacking arginine at position-2 by mitochondrial processing peptidase: Processing of bovine cytochrome P450(SCC) precursor<br>J Biochem (2001) 130, 497-502. PubMed  Europe PubMed
  46. [YEAR:19-1-2001]Kojima,K., Kitada,S., Ogishima,T. and Ito,A.<br>A proposed common structure of substrates bound to mitochondrial processing peptidase<br>J Biol Chem (19-1-2001) 276, 2115-2121. PubMed  Europe PubMed DOI
  47. [YEAR:3-7-2001]Taylor,A.B., Smith,B.S., Kitada,S., Kojima,K., Miyaura,H., Otwinowski,Z., Ito,A. and Deisenhofer,J.<br>Crystal structures of mitochondrial processing peptidase reveal the mode for specific cleavage of import signal sequences<br>Structure (3-7-2001) 9, 615-625. PubMed  Europe PubMed DOI  S
  48. Zhang,X.P., Sjoling,S., Tanudji,M., Somogyi,L., Andreu,D., Eriksson,L.E., Graslund,A., Whelan,J. and Glaser,E.<br>Mutagenesis and computer modelling approach to study determinants for recognition of signal peptides by the mitochondrial processing peptidase<br>Plant J (2001) 27, 427-438. PubMed  Europe PubMed DOI
    49. 2000
  49. [YEAR:29-12-2000]Cavadini,P., Adamec,J., Taroni,F., Gakh,O. and Isaya,G.<br>Two-step processing of human frataxin by mitochondrial processing peptidase. Precursor and intermediate forms are cleaved at different rates<br>J Biol Chem (29-12-2000) 275, 41469-41475. PubMed  Europe PubMed DOI
    50. 1999
  50. [YEAR:6-8-1999]Branda,S.S., Cavadini,P., Adamec,J., Kalousek,F., Taroni,F. and Isaya,G.<br>Yeast and human frataxin are processed to mature form in two sequential steps by the mitochondrial processing peptidase<br>J Biol Chem (6-8-1999) 274, 22763-22769. PubMed  Europe PubMed DOI
  51. Glaser,E. and Dessi,P.<br>Integration of the mitochondrial-processing peptidase into the cytochrome bc1 complex in plants<br>J Bioenerg Biomembr (1999) 31, 259-274. PubMed  Europe PubMed DOI
  52. [YEAR:30-11-1999]Ito,A.<br>Mitochondrial processing peptidase: multiple-site recognition of precursor proteins<br>Biochem Biophys Res Commun (30-11-1999) 265, 611-616. PubMed  Europe PubMed DOI
  53. Makarova,K.S. and Grishin,N.V.<br>Thermolysin and mitochondrial processing peptidase: how far structure-functional convergence goes<br>Protein Sci (1999) 8, 2537-2540. PubMed  Europe PubMed DOI  PMC  EPMC
  54. Moriwaki,K., Ogishima,T. and Ito,A.<br>Analysis of recognition elements for mitochondrial processing peptidase using artificial amino acids: Roles of the intervening portion and proximal arginine<br>J Biochem (1999) 126, 874-878. PubMed  Europe PubMed
    55. 1998
  55. [YEAR:22-5-1998]Brumme,S., Kruft,V., Schmitz,U.K. and Braun,H.P.<br>New insights into the co-evolution of cytochrome c reductase and the mitochondrial processing peptidase<br>J Biol Chem (22-5-1998) 273, 13143-13149. PubMed  Europe PubMed DOI
  56. [YEAR:14-8-1998]Deng,K., Zhang,L., Kachurin,A.M., Yu,L., Xia,D., Kim,H., Deisenhofer,J. and Yu,C.A.<br>Activation of a matrix processing peptidase from the crystalline cytochrome bc1 complex of bovine heart mitochondria<br>J Biol Chem (14-8-1998) 273, 20752-20757. PubMed  Europe PubMed DOI
  57. [YEAR:3-7-1998]Iwata,S., Lee,J.W., Okada,K., Lee,J.K., Iwata,M., Rasmussen,B., Link,T.A., Ramaswamy,S. and Jap,B.K.<br>Complete structure of the 11-subunit bovine mitochondrial cytochrome bc1 complex<br>Science (3-7-1998) 281, 64-71. PubMed  Europe PubMed DOI  S
  58. [YEAR:4-12-1998]Kitada,S., Kojima,K., Shimokata,K., Ogishima,T. and Ito,A.<br>Glutamate residues required for substrate binding and cleavage activity in mitochondrial processing peptidase<br>J Biol Chem (4-12-1998) 273, 32547-32553. PubMed  Europe PubMed DOI
  59. [YEAR:4-12-1998]Kojima,K., Kitada,S., Shimokata,K., Ogishima,T. and Ito,A.<br>Cooperative formation of a substrate binding pocket by alpha- and beta-subunits of mitochondrial processing peptidase<br>J Biol Chem (4-12-1998) 273, 32542-32546. PubMed  Europe PubMed DOI
  60. [YEAR:10-7-1998]Luciano,P., Tokatlidis,K., Chambre,I., Germanique,J.C. and Geli,V.<br>The mitochondrial processing peptidase behaves as a zinc-metallopeptidase<br>J Mol Biol (10-7-1998) 280, 193-199. PubMed  Europe PubMed DOI
  61. [YEAR:1-1-1998]Schneider,G., Sjoling,S., Wallin,E., Wrede,P., Glaser,E. and von Heijne,G.<br>Feature-extraction from endopeptidase cleavage sites in mitochondrial targeting peptides<br>Proteins (1-1-1998) 30, 49-60. PubMed  Europe PubMed DOI
  62. [YEAR:25-9-1998]Shimokata,K., Kitada,S., Ogishima,T. and Ito,A.<br>Role of alpha-subunit of mitochondrial processing peptidase in substrate recognition<br>J Biol Chem (25-9-1998) 273, 25158-25163. PubMed  Europe PubMed DOI
  63. Song,M.C., Ogishima,T. and Ito,A.<br>Importance of residues carboxyl terminal relative to the cleavage site in substrates of mitochondrial processing peptidase for their specific recognition and cleavage<br>J Biochem (1998) 124, 1045-1049. PubMed  Europe PubMed
    64. 1997
  64. Braun,H.P., Jansch,L. and Schmitz,U.K.<br>Potato mitochondrial processing peptidase complex<br>[ISSN:ISBN 90 5199 322 6 (IOS Press)] (1997) , 290-297.
  65. Braun,H.P. and Schmitz,U.K.<br>The mitochondrial processing peptidase<br>Int J Biochem Cell Biol (1997) 29, 1043-1045. PubMed  Europe PubMed DOI
  66. Nett,J.H., Denke,E. and Trumpower,B.L.<br>Two-step processing is not essential for the import and assembly of functionally active iron-sulfur protein into the cytochrome bc1 complex in Saccharomyces cerevisiae<br>J Biol Chem (1997) 272, 2212-2217. PubMed  Europe PubMed DOI
  67. [YEAR:4-7-1997]Xia,D., Yu,C.A., Kim,H., Xia,J.Z., Kachurin,A.M., Zhang,L., Yu,L. and Deisenhofer,J.<br>Crystal structure of the cytochrome bc1 complex from bovine heart mitochondria<br>Science (4-7-1997) 277, 60-66. PubMed  Europe PubMed DOI  S
    68. 1996
  68. Klaus,C., Guiard,B., Neupert,W. and Brunner,M.<br>Determinants in the presequence of cytochrome b2 for import into mitochondria and for proteolytic processing<br>Eur J Biochem (1996) 236, 856-861. PubMed  Europe PubMed
    69. 1995
  69. Braun,H.P. and Schmitz,U.K.<br>Cytochrome-c reductase/processing peptidase complex from potato mitochondria<br>Methods Enzymol (1995) 260, 70-82. PubMed  Europe PubMed DOI  V
    70. 1994
  70. Arretz,M., Schneider,H., Guiard,B., Brunner,M. and Neupert,W.<br>Characterization of the mitochondrial processing peptidase of Neurospora crassa<br>J Biol Chem (1994) 269, 4959-4967. PubMed  Europe PubMed
  71. Bassham,D.C., Creighton,A.M., Arretz,M., Brunner,M. and Robinson,C.<br>Efficient but aberrant cleavage of mitochondrial precursor proteins by the chloroplast stromal processing peptidase<br>Eur J Biochem (1994) 221, 523-528. PubMed  Europe PubMed
  72. Braun,H.P., Kruft,V. and Schmitz,U.K.<br>Molecular identification of the ten subunits of cytochrome-c reductase from potato mitochondria<br>Planta (1994) 193, 99-106. PubMed  Europe PubMed
  73. Sjoling,S., Eriksson,A.C. and Glaser,E.<br>A helical element in the C-terminal domain of the N. plumbaginifolia F1 beta presequence is important for recognition by the mitochondrial processing peptidase<br>J Biol Chem (1994) 269, 32059-32062. PubMed  Europe PubMed
    74. 1993
  74. Kalousek,F., Neupert,W., Omura,T., Schatz,G. and Schmitz,U.K.<br>Uniform nomenclature for the mitochondrial peptidases cleaving precursors of mitochondrial proteins<br>Trends Biochem Sci (1993) 18, 249-249. PubMed  Europe PubMed DOI
  75. Paces,V., Rosenberg,L.E., Fenton,W.A. and Kalousek,F.<br>The beta subunit of the mitochondrial processing peptidase from rat liver: Cloning and sequencing of a cDNA and comparison with a proposed family of metallopeptidases<br>Proc Natl Acad Sci U S A (1993) 90, 5355-5358. PubMed  Europe PubMed  PMC  EPMC
    76. 1992
  76. Eriksson,A.C. and Glaser,E.<br>Mitochondrial processing proteinase - a general processing proteinase of spinach leaf mitochondria is a membrane-bound enzyme<br>Biochim Biophys Acta Bioenerg (1992) 1140, 208-214. DOI
    77. 1991
  77. Rawlings,N.D. and Barrett,A.J.<br>Homologues of insulinase, a new superfamily of metalloendopeptidases<br>Biochem J (1991) 275, 389-391. PubMed  Europe PubMed  PMC  EPMC
  78. Whelan,J., Knorpp,C., Harmey,M.A. and Glaser,E.<br>Specificity of leaf mitochondrial and chloroplast processing systems for nuclear-encoded precursor proteins<br>Plant Mol Biol (1991) 16, 283-292. PubMed  Europe PubMed DOI
    79. 1990
  79. Gavel,Y. and von Heijne,G.<br>Cleavage-site motifs in mitochondrial targeting peptides<br>Protein Eng (1990) 4, 33-37. PubMed  Europe PubMed
  80. Kleiber,J., Kalousek,F., Swaroop,M. and Rosenberg,L.E.<br>The general mitochondrial matrix processing protease from rat liver: Structural characterization of the catalytic subunit<br>Proc Natl Acad Sci U S A (1990) 87, 7978-7982. PubMed  Europe PubMed  PMC  EPMC
  81. Schneider,H., Arretz,M., Wachter,E. and Neupert,W.<br>Matrix processing peptidase of mitochondria. Structure-function relationships<br>J Biol Chem (1990) 265, 9881-9887. PubMed  Europe PubMed
    82. 1989
  82. Hendrick,J.P., Hodges,P.E. and Rosenberg,L.E.<br>Survey of amino-terminal proteolytic cleavage sites in mitochondrial precursor proteins: leader peptides cleaved by two matrix proteases share a three-amino acid motif<br>Proc Natl Acad Sci U S A (1989) 86, 4056-4060. PubMed  Europe PubMed  PMC  EPMC
  83. Ou,W.J., Ito,A., Okazaki,H. and Omura,T.<br>Purification and characterization of a processing protease from rat liver mitochondria<br>EMBO J (1989) 8, 2605-2612. PubMed  Europe PubMed  PMC  EPMC
    84. 1988
  84. Jensen,R.E. and Yaffe,M.P.<br>Import of proteins into yeast mitochondria: the nuclear MAS2 gene encodes a component of the processing protease that is homologous to the MAS1-encoded subunit<br>EMBO J (1988) 7, 3863-3871. PubMed  Europe PubMed  PMC  EPMC
  85. Kalousek,F., Hendrick,J.P. and Rosenberg,L.E.<br>Two mitochondrial matrix proteases act sequentially in the processing of mammalian matrix enzymes<br>Proc Natl Acad Sci U S A (1988) 85, 7536-7540. PubMed  Europe PubMed  PMC  EPMC
  86. Witte,C., Jensen,R.E., Yaffe,M.P. and Schatz,G.<br>MAS1, a gene essential for yeast mitochondrial assembly, encodes a subunit of the mitochondrial processing protease<br>EMBO J (1988) 7, 1439-1447. PubMed  Europe PubMed  PMC  EPMC
    87. 1987
  87. Sztul,E.S., Hendrick,J.P., Kraus,J.P., Wall,D., Kalousek,F. and Rosenberg,L.E.<br>Import of rat ornithine transcarbamylase precursor into mitochondria: two-step processing of the leader peptide<br>J Cell Biol (1987) 105, 2631-2639. PubMed  Europe PubMed  PMC  EPMC
    88. 1986
  88. Miura,S., Amaya,Y. and Mori,M.<br>A metalloprotease involved in the processing of mitochondrial precursor proteins<br>Biochem Biophys Res Commun (1986) 134, 1151-1159. PubMed  Europe PubMed
    89. 1982
  89. Conboy,J.G., Fenton,W.A. and Rosenberg,L.E.<br>Processing of pre-ornithine transcarbamylase requires a zinc-dependent protease localized to the mitochondrial matrix<br>Biochem Biophys Res Commun (1982) 105, 1-7. PubMed  Europe PubMed
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