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Literature for peptidase M16.003: mitochondrial processing peptidase beta-subunit

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, M Mutation, P Specificity, I Inhibitor, L Localization, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Ludwig,K. and Heidorn-Czarna,M.
    Mitochondrial Proteases and Their Roles in Mitophagy in Plants, Animals, and Yeast
    Plant Cell Physiol PubMed  Europe PubMed DOI  V
    2. 2024
  2. Kucukkose,C., Vogtle,F.N. and Flotho,A.
    Monitoring mitochondrial precursor processing and presequence peptide degradation
    Methods Enzymol706, 193-213. PubMed  Europe PubMed DOI
    3. 2023
  3. Bayne,A.N., Dong,J., Amiri,S., Farhan,S.M.K. and Trempe,J.F.
    MTSviewer: A database to visualize mitochondrial targeting sequences, cleavage sites, and mutations on protein structures
    PLoS ONE18, e0284541-e0284541. PubMed  Europe PubMed DOI
  4. Moe,A., Dimogkioka,A.R., Rapaport,D., Ojemyr,L.N. and Brzezinski,P.
    Structure and function of the S. pombe III-IV-cyt c supercomplex
    Proc Natl Acad Sci U S A120, e2307697120-e2307697120. PubMed  Europe PubMed DOI
    5. 2022
  5. Heidorn-Czarna,M., Maziak,A. and Janska,H.
    Protein Processing in Plant Mitochondria Compared to Yeast and Mammals
    Front Plant Sci13, 824080-824080. PubMed  Europe PubMed DOI  V
    6. 2021
  6. Sim,J., Park,J., Woo,H.A. and Rhee,S.G.
    Maturation of Mitochondrially Targeted Prx V Involves a Second Cleavage by Mitochondrial Intermediate Peptidase That Is Sensitive to Inhibition by H2O2
    Antioxidants (Basel)10, PubMed  Europe PubMed DOI
    7. 2020
  7. Xiang,N., Guo,C., Liu,J., Xu,H., Dixon,R., Yang,J. and Wang,Y.P.
    Using synthetic biology to overcome barriers to stable expression of nitrogenase in eukaryotic organelles
    Proc Natl Acad Sci U S A117, 16537-16545. PubMed  Europe PubMed DOI
    8. 2019
  8. Lhouvum,K., Balaji,S.N., Ahsan,M.J. and Trivedi,V.
    Plasmodium falciparum PFI1625c offers an opportunity to design potent anti-malarials: biochemical characterization and testing potentials in drug discovery
    Acta Trop191, 116-127. PubMed  Europe PubMed DOI  I
    9. 2018
  9. Vogtle,F.N., Brandl,B., Larson,A., Pendziwiat,M., Friederich,M.W., White,S.M., Basinger,A., Kucukkose,C., Muhle,H., Jahn,J.A., Keminer,O., Helbig,K.L., Delto,C.F., Myketin,L., Mossmann,D., Burger,N., Miyake,N., Burnett,A., van Baalen,A., Lovell,M.A., Matsumoto,N., Walsh,M., Yu,H.C., Shinde,D.N., Stephani,U., Van Hove,J.L.K., Muller,F.J. and Helbig,I.
    Mutations in PMPCB encoding the catalytic subunit of the mitochondrial presequence protease cause neurodegeneration in early childhood
    Am J Hum Genet102, 557-573. PubMed  Europe PubMed DOI  M
    10. 2016
  10. Dasari,S. and Kolling,R.
    Role of mitochondrial processing peptidase and AAA proteases in processing of the yeast acetohydroxyacid synthase precursor
    FEBS Open Bio6, 765-773. PubMed  Europe PubMed DOI  M
    11. 2015
  11. Burkhart,J.M., Taskin,A.A., Zahedi,R.P. and Vogtle,F.N.
    Quantitative profiling for substrates of the mitochondrial presequence processing protease reveals a set of nonsubstrate proteins increased upon proteotoxic stress
    J Proteome Res14, 4550-4563. PubMed  Europe PubMed DOI  P
    12. 2014
  12. Pandey,D., Bhunia,A., Oh,Y.J., Chang,F., Bergman,Y., Kim,J.H., Serbo,J., Boronina,T.N., Cole,R.N., Van Eyk,J., Remaley,A.T., Berkowitz,D.E. and Romer,L.H.
    OxLDL triggers retrograde translocation of arginase2 in aortic endothelial cells via ROCK and mitochondrial processing peptidase
    Circ Res115, 450-459. PubMed  Europe PubMed DOI
    13. 2013
  13. Kucera,T., Otyepka,M., Matuskova,A., Samad,A., Kutejova,E. and Janata,J.
    A computational study of the glycine-rich loop of mitochondrial processing peptidase
    PLoS ONE8, e74518-e74518. PubMed  Europe PubMed DOI
  14. Mach,J., Poliak,P., Matuskova,A., Zarsky,V., Janata,J., Lukes,J. and Tachezy,J.
    An advanced system of the mitochondrial processing peptidase and core protein family in Trypanosoma brucei and multiple origins of the core I subunit in eukaryotes
    Genome Biol Evol5, 860-875. PubMed  Europe PubMed DOI
  15. Teixeira,P.F. and Glaser,E.
    Processing peptidases in mitochondria and chloroplasts
    Biochim Biophys Acta1833, 360-370. PubMed  Europe PubMed DOI  V
    16. 2012
  16. Desy,S., Schneider,A. and Mani,J.
    Trypanosoma brucei has a canonical mitochondrial processing peptidase
    Mol Biochem Parasitol185, 161-164. PubMed  Europe PubMed DOI
  17. Greene,A.W., Grenier,K., Aguileta,M.A., Muise,S., Farazifard,R., Haque,M.E., McBride,H.M., Park,D.S. and Fon,E.A.
    Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment
    EMBO Rep13, 378-385. PubMed  Europe PubMed DOI
  18. Kmiec,B., Urantowka,A., Lech,M. and Janska,H.
    Two-step processing of AtFtsH4 precursor by mitochondrial processing peptidase in Arabidopsis thaliana
    Mol Plant5, 1417-1419. PubMed  Europe PubMed DOI
  19. Kutejova,E., Kucera,T., Matuskova,A. and Janata,J.
    Mitochondrial processing peptidase
    [ISSN:978-0-12-407744-7]3, 1435-1442. DOI
  20. Mossmann,D., Meisinger,C. and Vogtle,F.N.
    Processing of mitochondrial presequences
    Biochim Biophys Acta1819, 1098-1106. PubMed  Europe PubMed DOI  V
    21. 2011
  21. Amata,O., Marino,T., Russo,N. and Toscano,M.
    A proposal for mitochondrial processing peptidase catalytic mechanism
    J Am Chem Soc133, 17824-17831. PubMed  Europe PubMed DOI
    22. 2010
  22. Dvorakova-Hola,K., Matuskova,A., Kubala,M., Otyepka,M., Kucera,T., Vecer,J., Herman,P., Parkhomenko,N., Kutejova,E. and Janata,J.
    Glycine-rich loop of mitochondrial processing peptidase alpha-subunit is responsible for substrate recognition by a mechanism analogous to mitochondrial receptor Tom20
    J Mol Biol396, 1197-1210. PubMed  Europe PubMed DOI
  23. Porras,P., McDonagh,B., Pedrajas,J.R., Barcena,J.A. and Padilla,C.A.
    Structure and function of yeast glutaredoxin 2 depend on postranslational processing and are related to subcellular distribution
    Biochim Biophys Acta1804, 839-845. PubMed  Europe PubMed DOI  P
    24. 2009
  24. Carrie,C., Giraud,E. and Whelan,J.
    Protein transport in organelles: dual targeting of proteins to mitochondria and chloroplasts
    FEBS J276, 1187-1195. PubMed  Europe PubMed DOI
    25. 2008
  25. Nagayama,K., Itono,S., Yoshida,T., Ishiguro,S., Ochiai,H. and Ohmachi,T.
    Antisense RNA inhibition of the beta subunit of the Dictyostelium discoideum mitochondrial processing peptidase induces the expression of mitochondrial proteins
    Biosci Biotechnol Biochem72, 1836-1846. PubMed  Europe PubMed DOI
  26. Schmucker,S., Argentini,M., Carelle-Calmels,N., Martelli,A. and Puccio,H.
    The in vivo mitochondrial two-step maturation of human frataxin
    Hum Mol Genet17, 3521-3531. PubMed  Europe PubMed DOI
  27. Smid,O., Matuskova,A., Harris,S.R., Kucera,T., Novotny,M., Horvathova,L., Hrdy,I., Kutejova,E., Hirt,R.P., Embley,T.M., Janata,J. and Tachezy,J.
    Reductive evolution of the mitochondrial processing peptidases of the unicellular parasites Trichomonas vaginalis and Giardia intestinalis
    PLoS Pathog4, e1000243-e1000243. PubMed  Europe PubMed DOI
    28. 2007
  28. Mukhopadhyay,A., Yang,C.S., Wei,B. and Weiner,H.
    Precursor protein is readily degraded in mitochondrial matrix space if the leader is not processed by mitochondrial processing peptidase
    J Biol Chem282, 37266-37275. PubMed  Europe PubMed DOI
  29. Nishino,T.G., Kitano,K., Kojima,K., Ogishima,T., Ito,A. and Kitada,S.
    Spatial orientation of mitochondrial processing peptidase and a preprotein revealed by fluorescence resonance energy transfer
    J Biochem141, 889-895. PubMed  Europe PubMed DOI  L
    30. 2006
  30. Khalimonchuk,O., Ott,M., Funes,S., Ostermann,K., Rodel,G. and Herrmann,J.M.
    Sequential processing of a mitochondrial tandem protein: insights into protein import in Schizosaccharomyces pombe
    Eukaryot Cell5, 997-1006. PubMed  Europe PubMed DOI
    31. 2005
  31. [YEAR:1-10-2005]Oshima,T., Yamasaki,E., Ogishima,T., Kadowaki,K., Ito,A. and Kitada,S.
    Recognition and processing of a nuclear-encoded polyprotein precursor by mitochondrial processing peptidase
    Biochem J385, 755-761. PubMed  Europe PubMed DOI
    32. 2004
  32. Braun,H.P. and Schmitz,U.K.
    Mitochondrial processing peptidase
    [ISSN:0-12-079610-4]2, 882-886.  V
  33. Janata,J., Hola,K., Kubala,M., Gakh,O., Parkhomenko,N., Matuskova,A., Kutejova,E. and Amler,E.
    Substrate evokes translocation of both domains in the mitochondrial processing peptidase alpha-subunit during which the C-terminus acts as a stabilizing element
    Biochem Biophys Res Commun316, 211-217. PubMed  Europe PubMed DOI
  34. Rudhe,C., Clifton,R., Chew,O., Zemam,K., Richter,S., Lamppa,G., Whelan,J. and Glaser,E.
    Processing of the dual targeted precursor protein of glutathione reductase in mitochondria and chloroplasts
    J Mol Biol343, 639-647. PubMed  Europe PubMed DOI
    35. 2003
  35. [YEAR:17-1-2003]Kitada,S., Yamasaki,E., Kojima,K. and Ito,A.
    Determination of the cleavage site of the presequence by mitochondrial processing peptidase on the substrate binding scaffold and the multiple subsites inside a molecular cavity
    J Biol Chem278, 1879-1885. PubMed  Europe PubMed DOI
    36. 2002
  36. [YEAR:2-9-2002]Gakh,O., Cavadini,P. and Isaya,G.
    Mitochondrial processing peptidases
    Biochim Biophys Acta1592, 63-77. PubMed  Europe PubMed DOI
  37. Mukhopadhyay,A., Hammen,P., Waltner-Law,M. and Weiner,H.
    Timing and structural consideration for the processing of mitochondrial matrix space proteins by the mitochondrial processing peptidase (MPP)
    Protein Sci11, 1026-1035. PubMed  Europe PubMed DOI
    38. 2001
  38. [YEAR:2-3-2001]Deng,K., Shenoy,S.K., Tso,S.C., Yu,L. and Yu,C.A.
    Reconstitution of mitochondrial processing peptidase from the core proteins (subunits I and II) of bovine heart mitochondrial cytochrome bc(1) complex
    J Biol Chem276, 6499-6505. PubMed  Europe PubMed DOI
  39. [YEAR:15-1-2001]Gakh,O., Obsil,T., Adamec,J., Spizek,J., Amler,E., Janata,J. and Kalousek,F.
    Substrate binding changes conformation of the alpha-, but not the beta-subunit of mitochondrial processing peptidase
    Arch Biochem Biophys385, 392-396. PubMed  Europe PubMed DOI
  40. [YEAR:1-2-2001]Gordon,D.M., Kogan,M., Knight,S.A.B., Dancis,A. and Pain,D.
    Distinct roles for two N-terminal cleaved domains in mitochondrial import of the yeast frataxin homolog, Yfh1p
    Hum Mol Genet10, 259-269. PubMed  Europe PubMed
  41. [YEAR:28-9-2001]Kitada,S., Kojima,K. and Ito,A.
    Glu(191) and Asp(195) in rat mitochondrial processing peptidase beta subunit are involved in effective cleavage of precursor protein through interaction with the proximal arginine
    Biochem Biophys Res Commun287, 594-599. PubMed  Europe PubMed DOI
  42. Kitada,S. and Ito,A.
    Electrostatic recognition of matrix targeting signal by mitochondrial processing peptidase
    J Biochem129, 155-161. PubMed  Europe PubMed
  43. [YEAR:19-1-2001]Kojima,K., Kitada,S., Ogishima,T. and Ito,A.
    A proposed common structure of substrates bound to mitochondrial processing peptidase
    J Biol Chem276, 2115-2121. PubMed  Europe PubMed DOI
  44. Kojima,K., Yamasaki,E., Kitada,S., Ogishima,T. and Ito,A.
    Recognition of mitochondrial protein precursor lacking arginine at position-2 by mitochondrial processing peptidase: Processing of bovine cytochrome P450(SCC) precursor
    J Biochem130, 497-502. PubMed  Europe PubMed
  45. [YEAR:3-7-2001]Taylor,A.B., Smith,B.S., Kitada,S., Kojima,K., Miyaura,H., Otwinowski,Z., Ito,A. and Deisenhofer,J.
    Crystal structures of mitochondrial processing peptidase reveal the mode for specific cleavage of import signal sequences
    Structure9, 615-625. PubMed  Europe PubMed DOI  S
  46. Zhang,X.P., Sjoling,S., Tanudji,M., Somogyi,L., Andreu,D., Eriksson,L.E., Graslund,A., Whelan,J. and Glaser,E.
    Mutagenesis and computer modelling approach to study determinants for recognition of signal peptides by the mitochondrial processing peptidase
    Plant J27, 427-438. PubMed  Europe PubMed DOI
    47. 2000
  47. [YEAR:29-12-2000]Cavadini,P., Adamec,J., Taroni,F., Gakh,O. and Isaya,G.
    Two-step processing of human frataxin by mitochondrial processing peptidase. Precursor and intermediate forms are cleaved at different rates
    J Biol Chem275, 41469-41475. PubMed  Europe PubMed DOI
    48. 1999
  48. [YEAR:6-8-1999]Branda,S.S., Cavadini,P., Adamec,J., Kalousek,F., Taroni,F. and Isaya,G.
    Yeast and human frataxin are processed to mature form in two sequential steps by the mitochondrial processing peptidase
    J Biol Chem274, 22763-22769. PubMed  Europe PubMed DOI
  49. Glaser,E. and Dessi,P.
    Integration of the mitochondrial-processing peptidase into the cytochrome bc1 complex in plants
    J Bioenerg Biomembr31, 259-274. PubMed  Europe PubMed DOI
  50. [YEAR:30-11-1999]Ito,A.
    Mitochondrial processing peptidase: multiple-site recognition of precursor proteins
    Biochem Biophys Res Commun265, 611-616. PubMed  Europe PubMed DOI
  51. Makarova,K.S. and Grishin,N.V.
    Thermolysin and mitochondrial processing peptidase: how far structure-functional convergence goes
    Protein Sci8, 2537-2540. PubMed  Europe PubMed DOI
  52. Moriwaki,K., Ogishima,T. and Ito,A.
    Analysis of recognition elements for mitochondrial processing peptidase using artificial amino acids: Roles of the intervening portion and proximal arginine
    J Biochem126, 874-878. PubMed  Europe PubMed
    53. 1998
  53. [YEAR:22-5-1998]Brumme,S., Kruft,V., Schmitz,U.K. and Braun,H.P.
    New insights into the co-evolution of cytochrome c reductase and the mitochondrial processing peptidase
    J Biol Chem273, 13143-13149. PubMed  Europe PubMed DOI
  54. [YEAR:14-8-1998]Deng,K., Zhang,L., Kachurin,A.M., Yu,L., Xia,D., Kim,H., Deisenhofer,J. and Yu,C.A.
    Activation of a matrix processing peptidase from the crystalline cytochrome bc1 complex of bovine heart mitochondria
    J Biol Chem273, 20752-20757. PubMed  Europe PubMed DOI
  55. [YEAR:3-7-1998]Iwata,S., Lee,J.W., Okada,K., Lee,J.K., Iwata,M., Rasmussen,B., Link,T.A., Ramaswamy,S. and Jap,B.K.
    Complete structure of the 11-subunit bovine mitochondrial cytochrome bc1 complex
    Science281, 64-71. PubMed  Europe PubMed DOI  S
  56. [YEAR:4-12-1998]Kitada,S., Kojima,K., Shimokata,K., Ogishima,T. and Ito,A.
    Glutamate residues required for substrate binding and cleavage activity in mitochondrial processing peptidase
    J Biol Chem273, 32547-32553. PubMed  Europe PubMed DOI
  57. [YEAR:4-12-1998]Kojima,K., Kitada,S., Shimokata,K., Ogishima,T. and Ito,A.
    Cooperative formation of a substrate binding pocket by alpha- and beta-subunits of mitochondrial processing peptidase
    J Biol Chem273, 32542-32546. PubMed  Europe PubMed DOI
  58. [YEAR:10-7-1998]Luciano,P., Tokatlidis,K., Chambre,I., Germanique,J.C. and Geli,V.
    The mitochondrial processing peptidase behaves as a zinc-metallopeptidase
    J Mol Biol280, 193-199. PubMed  Europe PubMed DOI
  59. [YEAR:1-1-1998]Schneider,G., Sjoling,S., Wallin,E., Wrede,P., Glaser,E. and von Heijne,G.
    Feature-extraction from endopeptidase cleavage sites in mitochondrial targeting peptides
    Proteins30, 49-60. PubMed  Europe PubMed DOI
  60. [YEAR:25-9-1998]Shimokata,K., Kitada,S., Ogishima,T. and Ito,A.
    Role of alpha-subunit of mitochondrial processing peptidase in substrate recognition
    J Biol Chem273, 25158-25163. PubMed  Europe PubMed DOI
  61. Song,M.C., Ogishima,T. and Ito,A.
    Importance of residues carboxyl terminal relative to the cleavage site in substrates of mitochondrial processing peptidase for their specific recognition and cleavage
    J Biochem124, 1045-1049. PubMed  Europe PubMed
    62. 1997
  62. Braun,H.P., Jansch,L. and Schmitz,U.K.
    Potato mitochondrial processing peptidase complex
    [ISSN:ISBN 90 5199 322 6 (IOS Press)]290-297.
  63. Braun,H.P. and Schmitz,U.K.
    The mitochondrial processing peptidase
    Int J Biochem Cell Biol29, 1043-1045. PubMed  Europe PubMed DOI
  64. Nett,J.H., Denke,E. and Trumpower,B.L.
    Two-step processing is not essential for the import and assembly of functionally active iron-sulfur protein into the cytochrome bc1 complex in Saccharomyces cerevisiae
    J Biol Chem272, 2212-2217. PubMed  Europe PubMed DOI
  65. [YEAR:4-7-1997]Xia,D., Yu,C.A., Kim,H., Xia,J.Z., Kachurin,A.M., Zhang,L., Yu,L. and Deisenhofer,J.
    Crystal structure of the cytochrome bc1 complex from bovine heart mitochondria
    Science277, 60-66. PubMed  Europe PubMed DOI  S
    66. 1996
  66. Klaus,C., Guiard,B., Neupert,W. and Brunner,M.
    Determinants in the presequence of cytochrome b2 for import into mitochondria and for proteolytic processing
    Eur J Biochem236, 856-861. PubMed  Europe PubMed
    67. 1995
  67. Braun,H.P. and Schmitz,U.K.
    Cytochrome-c reductase/processing peptidase complex from potato mitochondria
    Methods Enzymol260, 70-82. PubMed  Europe PubMed DOI  V
    68. 1994
  68. Arretz,M., Schneider,H., Guiard,B., Brunner,M. and Neupert,W.
    Characterization of the mitochondrial processing peptidase of Neurospora crassa
    J Biol Chem269, 4959-4967. PubMed  Europe PubMed
  69. Bassham,D.C., Creighton,A.M., Arretz,M., Brunner,M. and Robinson,C.
    Efficient but aberrant cleavage of mitochondrial precursor proteins by the chloroplast stromal processing peptidase
    Eur J Biochem221, 523-528. PubMed  Europe PubMed
  70. Braun,H.P., Kruft,V. and Schmitz,U.K.
    Molecular identification of the ten subunits of cytochrome-c reductase from potato mitochondria
    Planta193, 99-106. PubMed  Europe PubMed
  71. Sjoling,S., Eriksson,A.C. and Glaser,E.
    A helical element in the C-terminal domain of the N. plumbaginifolia F1 beta presequence is important for recognition by the mitochondrial processing peptidase
    J Biol Chem269, 32059-32062. PubMed  Europe PubMed
    72. 1993
  72. Kalousek,F., Neupert,W., Omura,T., Schatz,G. and Schmitz,U.K.
    Uniform nomenclature for the mitochondrial peptidases cleaving precursors of mitochondrial proteins
    Trends Biochem Sci18, 249-249. PubMed  Europe PubMed DOI
  73. Paces,V., Rosenberg,L.E., Fenton,W.A. and Kalousek,F.
    The beta subunit of the mitochondrial processing peptidase from rat liver: Cloning and sequencing of a cDNA and comparison with a proposed family of metallopeptidases
    Proc Natl Acad Sci U S A90, 5355-5358. PubMed  Europe PubMed
    74. 1992
  74. Eriksson,A.C. and Glaser,E.
    Mitochondrial processing proteinase - a general processing proteinase of spinach leaf mitochondria is a membrane-bound enzyme
    Biochim Biophys Acta Bioenerg1140, 208-214. DOI
    75. 1991
  75. Rawlings,N.D. and Barrett,A.J.
    Homologues of insulinase, a new superfamily of metalloendopeptidases
    Biochem J275, 389-391. PubMed  Europe PubMed
  76. Whelan,J., Knorpp,C., Harmey,M.A. and Glaser,E.
    Specificity of leaf mitochondrial and chloroplast processing systems for nuclear-encoded precursor proteins
    Plant Mol Biol16, 283-292. PubMed  Europe PubMed DOI
    77. 1990
  77. Gavel,Y. and von Heijne,G.
    Cleavage-site motifs in mitochondrial targeting peptides
    Protein Eng4, 33-37. PubMed  Europe PubMed
  78. Kleiber,J., Kalousek,F., Swaroop,M. and Rosenberg,L.E.
    The general mitochondrial matrix processing protease from rat liver: Structural characterization of the catalytic subunit
    Proc Natl Acad Sci U S A87, 7978-7982. PubMed  Europe PubMed
  79. Schneider,H., Arretz,M., Wachter,E. and Neupert,W.
    Matrix processing peptidase of mitochondria. Structure-function relationships
    J Biol Chem265, 9881-9887. PubMed  Europe PubMed
    80. 1989
  80. Hendrick,J.P., Hodges,P.E. and Rosenberg,L.E.
    Survey of amino-terminal proteolytic cleavage sites in mitochondrial precursor proteins: leader peptides cleaved by two matrix proteases share a three-amino acid motif
    Proc Natl Acad Sci U S A86, 4056-4060. PubMed  Europe PubMed
  81. Ou,W.J., Ito,A., Okazaki,H. and Omura,T.
    Purification and characterization of a processing protease from rat liver mitochondria
    EMBO J8, 2605-2612. PubMed  Europe PubMed
    82. 1988
  82. Jensen,R.E. and Yaffe,M.P.
    Import of proteins into yeast mitochondria: the nuclear MAS2 gene encodes a component of the processing protease that is homologous to the MAS1-encoded subunit
    EMBO J7, 3863-3871. PubMed  Europe PubMed
  83. Kalousek,F., Hendrick,J.P. and Rosenberg,L.E.
    Two mitochondrial matrix proteases act sequentially in the processing of mammalian matrix enzymes
    Proc Natl Acad Sci U S A85, 7536-7540. PubMed  Europe PubMed
  84. Witte,C., Jensen,R.E., Yaffe,M.P. and Schatz,G.
    MAS1, a gene essential for yeast mitochondrial assembly, encodes a subunit of the mitochondrial processing protease
    EMBO J7, 1439-1447. PubMed  Europe PubMed
    85. 1987
  85. Sztul,E.S., Hendrick,J.P., Kraus,J.P., Wall,D., Kalousek,F. and Rosenberg,L.E.
    Import of rat ornithine transcarbamylase precursor into mitochondria: two-step processing of the leader peptide
    J Cell Biol105, 2631-2639. PubMed  Europe PubMed
    86. 1986
  86. Miura,S., Amaya,Y. and Mori,M.
    A metalloprotease involved in the processing of mitochondrial precursor proteins
    Biochem Biophys Res Commun134, 1151-1159. PubMed  Europe PubMed
    87. 1982
  87. Conboy,J.G., Fenton,W.A. and Rosenberg,L.E.
    Processing of pre-ornithine transcarbamylase requires a zinc-dependent protease localized to the mitochondrial matrix
    Biochem Biophys Res Commun105, 1-7. PubMed  Europe PubMed
  88. Daum,G., Gasser,S.M. and Schatz,G.
    Import of proteins into mitochondria. Energy-dependent, two-step processing of the intermembrane space enzyme cytochrome b2 by isolated yeast mitochondria
    J Biol Chem257, 13075-13080. PubMed  Europe PubMed
  89. Miura,S., Mori,M., Amaya,Y. and Tatibana,M.
    A mitochondrial protease that cleaves the precursor of ornithine carbamoyltransferase. Purification and properties
    Eur J Biochem122, 641-647. PubMed  Europe PubMed
    90. 1980
  90. Bohni,P., Gasser,S., Leaver,C. and Schatz,G.
    A matrix-localized mitochondrial protease processing cytoplasmically-made precursors to mitochondrial proteins
    423-433.
  91. Mori,M., Miura,S., Tatibana,M. and Cohen,P.P.
    Characterization of a protease apparently involved in processing of pre-ornithine transcarbamylase of rat liver
    Proc Natl Acad Sci U S A77, 7044-7048. PubMed  Europe PubMed

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