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Literature for peptidase M14.028: cytosolic carboxypeptidase 1

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

(Topics flags: A Assay, M Mutation, P Specificity, I Inhibitor, K Knockout, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2024
  1. Bak,J., Brummelkamp,T.R. and Perrakis,A.<br>Decoding microtubule detyrosination: enzyme families, structures, and functional implications<br>FEBS Lett (2024) 598, 1453-1464. PubMed  Europe PubMed DOI  V
  2. Li,D.Z., Yang,Z.Y., Leng,A., Zhang,Q., Zhang,X.D., Bian,Y.C., Xiao,R. and Ren,J.J.<br>Targeting AGTPBP1 inhibits pancreatic cancer progression via regulating microtubules and ERK signaling pathway<br>Mol Med (2024) 30, 119-119. PubMed  Europe PubMed DOI  PMC  EPMC  K
    3. 2022
  3. Landskron,L., Bak,J., Adamopoulos,A., Kaplani,K., Moraiti,M., van den Hengel,L.G., Song,J.Y., Bleijerveld,O.B., Nieuwenhuis,J., Heidebrecht,T., Henneman,L., Moutin,M.J., Barisic,M., Taraviras,S., Perrakis,A. and Brummelkamp,T.R.<br>Posttranslational modification of microtubules by the MATCAP detyrosinase<br>Science (2022) 376, eabn6020-eabn6020. PubMed  Europe PubMed DOI
    4. 2021
  4. Koyanagi,T., Saga,Y., Takahashi,Y., Tamura,K., Yoshiba,T., Takahashi,S., Taneichi,A., Takei,Y., Urabe,M., Mizukami,H. and Fujiwara,H.<br>Knockout of vasohibin-2 reduces tubulin carboxypeptidase activity and increases paclitaxel sensitivity in ovarian cancer<br>Cancer Med (2021) 10, 2732-2739. PubMed  Europe PubMed DOI
    5. 2019
  5. Freund,R.R.A., Gobrecht,P., Rao,Z., Gerstmeier,J., Schlosser,R., Gorls,H., Werz,O., Fischer,D. and Arndt,H.D.<br>Stereoselective total synthesis of parthenolides indicates target selectivity for tubulin carboxypeptidase activity<br>Chem Sci (2019) 10, 7358-7364. PubMed  Europe PubMed DOI  PMC  EPMC  I
    6. 2018
  6. Zhou,L., Hossain,M.I., Yamazaki,M., Abe,M., Natsume,R., Konno,K., Kageyama,S., Komatsu,M., Watanabe,M., Sakimura,K. and Takebayashi,H.<br>Deletion of exons encoding carboxypeptidase domain of Nna1 results in Purkinje cell degeneration (pcd) phenotype<br>J Neurochem (2018) 147, 557-572. PubMed  Europe PubMed DOI
    7. 2015
  7. Song,N., Kim,N., Xiao,R., Choi,H., Chun,H.I., Kang,M.H., Kim,J.H., Seo,K., Soundrarajan,N., Do,J.T., Song,H., Ge,Z.J. and Park,C.<br>Lack of cytosolic carboxypeptidase 1 leads to subfertility due to the reduced number of antral follicles in pcd3J-/- females<br>PLoS ONE (2015) 10, e0139557-e0139557. PubMed  Europe PubMed DOI  PMC  EPMC
  8. Tanco,S., Tort,O., Demol,H., Aviles,F.X., Gevaert,K., Van Damme,P. and Lorenzo,J.<br>C-terminomics screen for natural substrates of cytosolic carboxypeptidase 1 reveals processing of acidic protein C termini<br>Mol Cell Proteomics (2015) 14, 177-190. PubMed  Europe PubMed DOI  P
    9. 2013
  9. Rodriguez de la Vega Otazo, Lorenzo,J., Tort,O., Aviles,F.X. and Bautista,J.M.<br>Functional segregation and emerging role of cilia-related cytosolic carboxypeptidases (CCPs)<br>FASEB J (2013) 27, 424-431. PubMed  Europe PubMed DOI
    10. 2012
  10. Berezniuk,I., Vu,H.T., Lyons,P.J., Sironi,J.J., Xiao,H., Burd,B., Setou,M., Angeletti,R.H., Ikegami,K. and Fricker,L.D.<br>Cytosolic carboxypeptidase 1 is involved in processing alpha- and beta-tubulin<br>J Biol Chem (2012) 287, 6503-6517. PubMed  Europe PubMed DOI
  11. Webster,D.R.<br>Tubulinyl-Tyr carboxypeptidase<br>[ISSN:978-0-12-407744-7] (2012) 3, 1385-1389. DOI
    12. 2010
  12. Berezniuk,I. and Fricker,L.D.<br>A defect in cytosolic carboxypeptidase 1 (Nna1) causes autophagy in Purkinje cell degeneration mouse brain<br>Autophagy (2010) 6, 558-559. PubMed  Europe PubMed DOI  M
  13. Rogowski,K., van Dijk,J., Magiera,M.M., Bosc,C., Deloulme,J.C., Bosson,A., Peris,L., Gold,N.D., Lacroix,B., Grau,M.B., Bec,N., Larroque,C., Desagher,S., Holzer,M., Andrieux,A., Moutin,M.J. and Janke,C.<br>A family of protein-deglutamylating enzymes associated with neurodegeneration<br>Cell (2010) 143, 564-578. PubMed  Europe PubMed DOI
    14. 2007
  14. Fonrose,X., Ausseil,F., Soleilhac,E., Masson,V., David,B., Pouny,I., Cintrat,J.C., Rousseau,B., Barette,C., Massiot,G. and Lafanechere,L.<br>Parthenolide inhibits tubulin carboxypeptidase activity<br>Cancer Res (2007) 67, 3371-3378. PubMed  Europe PubMed DOI
  15. Kalinina,E., Biswas,R., Berezniuk,I., Hermoso,A., Aviles,F.X. and Fricker,L.D.<br>A novel subfamily of mouse cytosolic carboxypeptidases<br>FASEB J (2007) 21, 836-850. PubMed  Europe PubMed DOI
  16. Rodriguez de la Vega,M., Sevilla,R.G., Hermoso,A., Lorenzo,J., Tanco,S., Diez,A., Fricker,L.D., Bautista,J.M. and Aviles,F.X.<br>Nna1-like proteins are active metallocarboxypeptidases of a new and diverse M14 subfamily<br>FASEB J (2007) 21, 851-865. PubMed  Europe PubMed DOI
    17. 2004
  17. Webster,D.R.<br>Tubulinyl-Tyr carboxypeptidase<br>[ISSN:0-12-079610-4] (2004) 2, 2111-2113.  V
    18. 2003
  18. Contin,M.A., Purro,S.A., Bisig,C.G., Barra,H.S. and Arce,C.A.<br>Inhibitors of protein phosphatase 1 and 2A decrease the level of tubulin carboxypeptidase activity associated with microtubules<br>Eur J Biochem (2003) 270, 4921-4929. PubMed  Europe PubMed DOI
    19. 2002
  19. [YEAR:23-8-2002]Chang,W., Webster,D.R., Salam,A.A., Gruber,D., Prasad,A., Eiserich,J.P. and Bulinski,J.C.<br>Alteration of the C-terminal amino acid of tubulin specifically inhibits myogenic differentiation<br>J Biol Chem (23-8-2002) 277, 30690-30698. PubMed  Europe PubMed DOI
  20. Lin,S.X., Gundersen,G.G. and Maxfield,F.R.<br>Export from pericentriolar endocytic recycling compartment to cell surface depends on stable, detyrosinated (Glu) microtubules and kinesin<br>Mol Biol Cell (2002) 13, 96-109. PubMed  Europe PubMed DOI  PMC  EPMC
    21. 2001
  21. [YEAR:1-7-2001]Mialhe,A., Lafanechere,L., Treilleux,I., Peloux,N., Dumontet,C., Bremond,A., Panh,M.H., Payan,R., Wehland,J., Margolis,R.L. and Job,D.<br>Tubulin detyrosination is a frequent occurrence in breast cancers of poor prognosis<br>Cancer Res (1-7-2001) 61, 5024-5027. PubMed  Europe PubMed
    22. 2000
  22. Contin,M.A. and Arce,C.A.<br>Tubulin carboxypeptidase/microtubules association can be detected in the distal region of neural processes<br>Neurochem Res (2000) 25, 27-36. PubMed  Europe PubMed DOI
  23. [YEAR:1-3-2000]Sironi,J.J., Barra,H.S. and Arce,C.A.<br>Tubulin carboxypeptidase assay based on the action of the enzyme on [14C]tyrosinated tubulin bound to nitrocellulose membrane<br>Anal Biochem (1-3-2000) 279, 9-17. PubMed  Europe PubMed DOI  A
    24. 1999
  24. [YEAR:15-4-1999]Contin,M.A., Sironi,J.J., Barra,H.S. and Arce,C.A.<br>Association of tubulin carboxypeptidase with microtubules in living cells<br>Biochem J (15-4-1999) 339, 463-471. PubMed  Europe PubMed DOI  PMC  EPMC
  25. Kreitzer,G., Liao,G. and Gundersen,G.G.<br>Detyrosination of tubulin regulates the interaction of intermediate filaments with microtubules in vivo via a kinesin-dependent mechanism<br>Mol Biol Cell (1999) 10, 1105-1118. PubMed  Europe PubMed  PMC  EPMC
    26. 1998
  26. [YEAR:17-4-1998]Liao,G. and Gundersen,G.G.<br>Kinesin is a candidate for cross-bridging microtubules and intermediate filaments. Selective binding of kinesin to detyrosinated tubulin and vimentin<br>J Biol Chem (17-4-1998) 273, 9797-9803. PubMed  Europe PubMed DOI
    27. 1997
  27. Weizetfel,J.C., Smania,A.M., Barra,H.S. and Argarana,C.E.<br>A brain protein (P30) that immunoreacts with a polyclonal anti-pancreatic carboxypeptidase A antibody shows properties that are shared with tubulin carboxypeptidase<br>Mol Cell Biochem (1997) 170, 139-146. PubMed  Europe PubMed DOI
    28. 1996
  28. Webster,D.R. and Oxford,M.G.<br>Regulation of cytoplasmic tubulin carboxypeptidase activity in vitro by cations and sulfhydryl-modifying compounds<br>J Cell Biochem (1996) 60, 424-436. PubMed  Europe PubMed DOI  I
    29. 1995
  29. Gurland,G. and Gundersen,G.G.<br>Stable, detyrosinated microtubules function to localize vimentin intermediate filaments in fibroblasts<br>J Cell Biol (1995) 131, 1275-1290. PubMed  Europe PubMed DOI  PMC  EPMC
    30. 1992
  30. Smania,A.M., Argarana,C.E., Weizetfel,J.C. and Barra,H.S.<br>Immunodetection of tubulin carboxypeptidase activity on nitrocellulose membrane after gel electrophoresis and blotting<br>Biochem Int (1992) 28, 921-928. PubMed  Europe PubMed
  31. Webster,D.R., Modesti,N.M. and Bulinski,J.C.<br>Regulation of cytoplasmic tubulin carboxypeptidase activity during neural and muscle differentiation: characterization using a microtubule-based assay<br>Biochemistry (1992) 31, 5849-5856. PubMed  Europe PubMed
    32. 1990
  32. Webster,D.R., Wehland,J., Weber,K. and Borisy,G.G.<br>Detyrosination of alpha tubulin does not stabilize microtubules in vivo<br>J Cell Biol (1990) 111, 113-122. PubMed  Europe PubMed DOI  PMC  EPMC
    33. 1989
  33. [YEAR:15-3-1989]Weizetfel,J.C., Argarana,C.E., Beltramo,D.M. and Barra,H.S.<br>The integrity of tubulin molecule is not required for the activity of tubulin carboxypeptidase<br>Biochem Biophys Res Commun (15-3-1989) 159, 770-776. PubMed  Europe PubMed
    34. 1987
  34. Wehland,J. and Weber,K.<br>Turnover of the carboxy-terminal tyrosine of alpha-tubulin and means of reaching elevated levels of detyrosination in living cells<br>J Cell Sci (1987) 88, 185-203. PubMed  Europe PubMed
    35. 1983
  35. [YEAR:27-6-1983]Arce,C.A. and Barra,H.S.<br>Association of tubulinyl-tyrosine carboxypeptidase with microtubules<br>FEBS Lett (27-6-1983) 157, 75-78. PubMed  Europe PubMed DOI
    36. 1981
  36. [YEAR:25-7-1981]Kumar,N. and Flavin,M.<br>Preferential action of a brain detyrosinolating carboxypeptidase on polymerized tubulin<br>J Biol Chem (25-7-1981) 256, 7678-7686. PubMed  Europe PubMed
    37. 1980
  37. Argarana,C.E., Barra,H.S. and Caputto,R.<br>Tubulinyl-tyrosine carboxypeptidase from chicken brain: properties and partial purification<br>J Neurochem (1980) 34, 114-118. PubMed  Europe PubMed
  38. Deanin,G.G., Preston,S.F., Hanson,R.K. and Gordon,M.W.<br>On the mechanism of turnover of the carboxy-terminal tyrosine of the alpha chain of tubulin<br>Eur J Biochem (1980) 109, 207-216. PubMed  Europe PubMed
    39. 1978
  39. [YEAR:24-2-1978]Argarana,C.E., Barra,H.S. and Caputto,R.<br>Release of [14C]tyrosine from tubulinyl-[14C]tyrosine by brain extract. Separation of a carboxypeptidase from tubulin-tyrosine ligase<br>Mol Cell Biochem (24-2-1978) 19, 17-21. PubMed  Europe PubMed
    40. 1977
  40. [YEAR:1-2-1977]Hallak,M.E., Rodriguez,J.A., Barra,H.S. and Caputto,R.<br>Release of tyrosine from tyrosinated tubulin. Some common factors that affect this process and the assembly of tubulin<br>FEBS Lett (1-2-1977) 73, 147-150. PubMed  Europe PubMed DOI

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