$VAR1 = undef;

Summary for peptidase M14.028: cytosolic carboxypeptidase 1

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

 

Names
MEROPS Namecytosolic carboxypeptidase 1
Other namesAGTPBP1 g.p. (Homo sapiens), carboxypeptidase-tubulin, CCP1, KIAA1035, hypothetical protein flj10682 (Homo sapiens), Mername-AA217 hypothetical peptidase, Nna1 protein, soluble carboxypeptidase, tubulinyl-Tyr carboxypeptidase, tubulin carboxypeptidase, tyrosine carboxypeptidase
Domain architecture
MEROPS Classification
Classification Clan MC >> Subclan (none) >> Family M14 >> Subfamily D >> M14.028
Holotypecytosolic carboxypeptidase 1 (Homo sapiens), Uniprot accession Q9UPW5 (peptidase unit: 836-1018), MERNUM MER0033179
History Identifier created: MEROPS 6.7 (29 June 2004)
Activity
Catalytic typeMetallo
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.17 (Metallocarboxypeptidases) >> Peptidase 3.4.17.17
EnzymologyBRENDA database
Proteolytic eventsCutDB database (2 cleavages)
Activity statushuman: putative
mouse: putative
Other databases TREEFAMhttp://www.treefam.org/family/TF313794
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage patternE/EG/E/EScissile bondEy/-/-/- (based on 17 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 6 3 0 0 0 0 0
Pro 0 0 0 0 0 0 0 0
Ala 0 0 0 0 0 0 0 0
Val 0 0 0 0 0 0 0 0
Leu 0 0 0 0 0 0 0 0
Ile 0 0 0 0 0 0 0 0
Met 1 0 0 0 0 0 0 0
Phe 0 0 0 0 1 0 0 0
Tyr 1 1 0 0 5 0 0 0
Trp 0 0 0 0 0 0 0 0
Ser 0 0 0 0 0 0 0 0
Thr 0 0 0 0 0 0 0 0
Cys 0 0 0 0 0 0 0 0
Asn 0 0 0 0 0 0 0 0
Gln 0 0 0 0 0 0 0 0
Asp 0 0 0 0 0 0 0 0
Glu 9 7 12 17 11 0 0 0
Lys 0 0 0 0 0 0 0 0
Arg 0 0 0 0 0 0 0 0
His 0 0 0 0 0 0 0 0
Human genetics
Gene symbol Locus Megabases Ensembl Entrez gene Gene Cards OMIM
AGTPBP1 9q22.1 ENSG00000135049 23287 AGTPBP1 606830
Mouse genetics
Gene symbol Position Megabases Ensembl Entrez gene MGI
Agtpbp1 13:B2 ENSMUSG00000021557 67269 MGI:2159437