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Literature for peptidase M12.133: fibrolase

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

(Topics flags: S Structure, P Specificity, I Inhibitor, E Expression, V Review, U Therapeutic. To select only the references relevant to a single topic, click the link above. See explanation.)

    2012
  1. Swenson,S. and Markland,F.S.<br>Fibrolase<br>[ISSN:978-0-12-407744-7] (2012) 3, 972-976. DOI
    2. 2011
  2. Fang,H.M., Zhao,L., Lu,P., Chen,S.J., Bao,Z.X., Qin,Y.F., Zhu,Z.Y., Zhao,J.M., Mai,J. and Zhang,S.T.<br>Modular design, expression and characterization of novel bifunctional mutants of fibrolase with combined platelet aggregation-inhibition and fibrinolytic activity<br>Protein J (2011) 30, 247-252. PubMed  Europe PubMed DOI  U
    3. 2010
  3. Han,S.M., Weaver,F.A., Comerota,A.J., Perler,B.A. and Joing,M.<br>Efficacy and safety of alfimeprase in patients with acute peripheral arterial occlusion (PAO)<br>J Vasc Surg (2010) 51, 600-609. PubMed  Europe PubMed DOI  U
  4. Marder,V.J. and Novokhatny,V.<br>Direct fibrinolytic agents: biochemical attributes, preclinical foundation and clinical potential<br>J Thromb Haemost (2010) 8, 433-444. PubMed  Europe PubMed DOI
    5. 2009
  5. Lu,A., Kurosawa,Y., Luskey,K., Pyne-Geithman,G., Caudell,D. and Clark,J.<br>Hemorrhagic profile of the fibrinolytic alfimeprase after ischemia and reperfusion<br>Neurol Res (2009) 31, 209-214. PubMed  Europe PubMed DOI  U
    6. 2008
  6. Moise,M.A. and Kashyap,V.S.<br>Alfimeprase for the treatment of acute peripheral arterial occlusion<br>Expert Opin Biol Ther (2008) 8, 683-689. PubMed  Europe PubMed DOI  U
    7. 2007
  7. Shi,J., Zhang,S.T., Zhang,X.J., Xu,H. and Guo,A.G.<br>Expression, purification, and activity identification of Alfimeprase in Pichia pastoris<br>Protein Expr Purif (2007) 54, 240-246. PubMed  Europe PubMed DOI  E
    8. 2006
  8. Deitcher,S.R., Funk,W.D., Buchanan,J., Liu,S., Levy,M.D. and Toombs,C.F.<br>Alfimeprase: a novel recombinant direct-acting fibrinolytic<br>Expert Opin Biol Ther (2006) 6, 1361-1369. PubMed  Europe PubMed DOI
  9. Hong,T.T., Huang,J. and Lucchesi,B.R.<br>Effect of thrombolysis on myocardial injury: recombinant tissue plasminogen activator vs. alfimeprase<br>Am J Physiol Heart Circ Physiol (2006) 290, H959-H967. PubMed  Europe PubMed DOI  U
  10. Moll,S., Kenyon,P., Bertoli,L., De Maio,J., Homesley,H. and Deitcher,S.R.<br>Phase II trial of alfimeprase, a novel-acting fibrin degradation agent, for occluded central venous access devices<br>J Clin Oncol (2006) 24, 3056-3060. PubMed  Europe PubMed DOI
  11. Reddy,G.K.<br>Clinical utility of novel agents in the treatment of central venous catheter occlusion<br>Support Cancer Ther (2006) 3, 135-139. PubMed  Europe PubMed DOI  U
  12. Swenson,S. and Markland,F.S.<br>Fibrolase<br>Toxin Rev (2006) 25, 351-378.
    13. 2005
  13. Deitcher,S.R. and Toombs,C.F.<br>Non-clinical and clinical characterization of a novel acting thrombolytic: alfimeprase<br>Pathophysiol Haemost Thromb (2005) 34, 215-220. PubMed  Europe PubMed DOI
  14. Ouriel,K., Cynamon,J., Weaver,F.A., Dardik,H., Akers,D., Blebea,J., Gruneiro,L., Toombs,C.F., Wang-Clow,F., Mohler,M., Pena,L., Wan,C.Y. and Deitcher,S.R.<br>A phase I trial of alfimeprase for peripheral arterial thrombolysis<br>J Vasc Interv Radiol (2005) 16, 1075-1083. PubMed  Europe PubMed DOI  U
  15. Swenson,S. and Markland,F.S., Jr.<br>Snake venom fibrin(ogen)olytic enzymes<br>Toxicon (2005) 45, 1021-1039. PubMed  Europe PubMed DOI
    16. 2004
  16. Swenson,S., Markland,F.S., Jr. and Toombs,C.<br>Fibrolase<br>[ISSN:0-12-079610-4] (2004) 2, 640-643.  V
  17. Swenson,S., Toombs,C.F., Pena,L., Johansson,J. and Markland,F.S., Jr.<br>Alpha-fibrinogenases<br>Curr Drug Targets Cardiovasc Haematol Disord (2004) 4, 417-435. PubMed  Europe PubMed DOI
    18. 2003
  18. Ramos,O.H., Carmona,A.K. and Selistre-De-Araujo,H.S.<br>Expression, refolding, and in vitro activation of a recombinant snake venom pro-metalloprotease<br>Protein Expr Purif (2003) 28, 34-41. PubMed  Europe PubMed DOI  E
    19. 2001
  19. Bolger,M.B., Swenson,S. and Markland,F.S.J.<br>Three-dimensional structure of fibrolase, the fibrinolytic enzyme from southern copperhead venom, modeled from the X-ray structure of adamalysin II and atrolysin C<br>AAPS PharmSci (2001) 3, E16-E16. PubMed  Europe PubMed DOI  S
  20. Jones,G., Ronk,M., Mori,F. and Zhang,Z.<br>Disulfide structure of alfimeprase: a recombinant analog of fibrolase<br>Protein Sci (2001) 10, 1264-1267. PubMed  Europe PubMed DOI  PMC  EPMC
  21. Toombs,C.F.<br>Alfimeprase: pharmacology of a novel fibrinolytic metalloproteinase for thrombolysis<br>Haemostasis (2001) 31, 141-147. PubMed  Europe PubMed
    22. 2000
  22. Selistre-De-Araujo,H.S., de Souza,E.L., Beltramini,L.M., Ownby,C.L. and Souza,D.H.<br>Expression, refolding, and activity of a recombinant nonhemorrhagic snake venom metalloprotease<br>Protein Expr Purif (2000) 19, 41-47. PubMed  Europe PubMed DOI  E
  23. [YEAR:15-12-2000]Swenson,S., Bush,L.R. and Markland,F.S.<br>Chimeric derivative of fibrolase, a fibrinolytic enzyme from southern copperhead venom, possesses inhibitory activity on platelet aggregation<br>Arch Biochem Biophys (15-12-2000) 384, 227-237. PubMed  Europe PubMed DOI
    24. 1998
  24. Swenson,S. and Markland,F.S.<br>PEGylation of fibrolase overcomes inhibition by alpha2-macroglobulin<br>Fibrinolysis Proteolysis (1998) 12 Suppl. 1, 29-29.
    25. 1997
  25. Sanchez,E.F., Bush,L.R., Swenson,S. and Markland,F.S.<br>Chimeric fibrolase: covalent attachment of an RGD-like peptide to create a potentially more effective thrombolytic agent<br>Thromb Res (1997) 87, 289-302. PubMed  Europe PubMed DOI
    26. 1996
  26. Markland,F.S.<br>Fibrolase, an active thrombolytic enzyme in arterial and venous thrombosis model systems<br>Adv Exp Med Biol (1996) 391, 427-438. PubMed  Europe PubMed  U
    27. 1995
  27. Manning,M.C.<br>Sequence analysis of fibrolase, a fibrinolytic metalloproteinase from Agkistrodon contortrix contortrix<br>Toxicon (1995) 33, 1189-1200. PubMed  Europe PubMed DOI
  28. Selistre de Araujo,H.S. and Ownby,C.L.<br>Molecular cloning and sequence analysis of cDNAs for metalloproteinases from broad-banded copperhead Agkistrodon contortrix laticinctus<br>Arch Biochem Biophys (1995) 320, 141-148. PubMed  Europe PubMed DOI
    29. 1994
  29. Loayza,S.L., Trikha,M., Markland,F.S., Riquelme,P. and Kuo,J.<br>Resolution of isoforms of natural and recombinant fibrolase, the fibrinolytic enzyme from Agkistrodon contortrix contortrix snake venom, and comparison of their EDTA sensitivities<br>J Chromatogr B Biomed Appl (1994) 662, 227-243. PubMed  Europe PubMed DOI  I
  30. Retzios,A.D. and Markland,F.S.<br>Fibrinolytic enzymes from the venoms of Agkistrodon contortrix contortrix and Crotalus basiliscus basiliscus: cleavage site specificity towards the alpha-chain of fibrin<br>Thromb Res (1994) 74, 355-367. PubMed  Europe PubMed DOI  P
  31. Trikha,M., Schmitmeier,S. and Markland,F.S.<br>Purification and characterization of fibrolase isoforms from venom of individual southern copperhead (Agkistrodon contortrix contortrix) snakes<br>Toxicon (1994) 32, 1521-1531. PubMed  Europe PubMed
    32. 1993
  32. Patton,L.M., Pretzer,D., Schulteis,B.S., Saggart,B.S., Tennant,K.D. and Ahmed,N.K.<br>Activity assays for characterizing the thrombolytic protein fibrolase<br>J Biochem Biophys Methods (1993) 27, 11-23. PubMed  Europe PubMed DOI
  33. Pretzer,D., Schulteis,B.S., Smith,C.D., Vander Velde,D.G., Mitchell,J.W. and Manning,M.C.<br>Fibrolase. A fibrinolytic protein from snake venom<br>Pharm Biotechnol (1993) 5, 287-314. PubMed  Europe PubMed  V
    34. 1992
  34. Pretzer,D., Schulteis,B., Vander Velde,D.G., Smith,C.D., Mitchell,J.W. and Manning,M.C.<br>Effect of zinc binding on the structure and stability of fibrolase, a fibrinolytic protein from snake venom<br>Pharm Res (1992) 9, 870-877. PubMed  Europe PubMed DOI
  35. Randolph,A., Chamberlain,S.H., Chu,H.L., Retzios,A.D., Markland,F.S., Jr. and Masiarz,F.R.<br>Amino acid sequence of fibrolase, a direct-acting fibrinolytic enzyme from Agkistrodon contortrix contortrix venom<br>Protein Sci (1992) 1, 590-600. PubMed  Europe PubMed DOI  PMC  EPMC
    36. 1991
  36. Guan,A.L., Retzios,A.D., Henderson,G.N. and Markland,F.S., Jr.<br>Purification and characterization of a fibrinolytic enzyme from venom of the southern copperhead snake (Agkistrodon contortrix contortrix)<br>Arch Biochem Biophys (1991) 289, 197-207. PubMed  Europe PubMed
    37. 1988
  37. Retzios,A.D. and Markland,F.S., Jr.<br>A direct-acting fibrinolytic enzyme from the venom of Agkistrodon contortrix contortrix: Effects on various components of the human blood coagulation and fibrinolysis systems<br>Thromb Res (1988) 52, 541-552. PubMed  Europe PubMed
    38. 1982
  38. Bajwa,S.S., Kirakossian,H., Reddy,K.N. and Markland,F.S.<br>Thrombin-like and fibrinolytic enzymes in the venoms from the Gaboon viper (Bitis gabonica), eastern cottonmouth moccasin (Agkistrodon p. piscivorus) and southern copperhead (Agkistrodon c. contortrix) snakes<br>Toxicon (1982) 20, 427-432. PubMed  Europe PubMed

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