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Literature for peptidase M12.133: fibrolase

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates Inhibitors

(Topics flags: S Structure, P Specificity, I Inhibitor, E Expression, V Review, U Therapeutic. To select only the references relevant to a single topic, click the link above. See explanation.)

    2012
  1. Swenson,S. and Markland,F.S.
    Fibrolase
    [ISSN:978-0-12-407744-7] (2012) 3, 972-976. DOI
    2. 2011
  2. Fang,H.M., Zhao,L., Lu,P., Chen,S.J., Bao,Z.X., Qin,Y.F., Zhu,Z.Y., Zhao,J.M., Mai,J. and Zhang,S.T.
    Modular design, expression and characterization of novel bifunctional mutants of fibrolase with combined platelet aggregation-inhibition and fibrinolytic activity
    Protein J (2011) 30, 247-252. PubMed  Europe PubMed DOI  U
    3. 2010
  3. Han,S.M., Weaver,F.A., Comerota,A.J., Perler,B.A. and Joing,M.
    Efficacy and safety of alfimeprase in patients with acute peripheral arterial occlusion (PAO)
    J Vasc Surg (2010) 51, 600-609. PubMed  Europe PubMed DOI  U
  4. Marder,V.J. and Novokhatny,V.
    Direct fibrinolytic agents: biochemical attributes, preclinical foundation and clinical potential
    J Thromb Haemost (2010) 8, 433-444. PubMed  Europe PubMed DOI
    5. 2009
  5. Lu,A., Kurosawa,Y., Luskey,K., Pyne-Geithman,G., Caudell,D. and Clark,J.
    Hemorrhagic profile of the fibrinolytic alfimeprase after ischemia and reperfusion
    Neurol Res (2009) 31, 209-214. PubMed  Europe PubMed DOI  U
    6. 2008
  6. Moise,M.A. and Kashyap,V.S.
    Alfimeprase for the treatment of acute peripheral arterial occlusion
    Expert Opin Biol Ther (2008) 8, 683-689. PubMed  Europe PubMed DOI  U
    7. 2007
  7. Shi,J., Zhang,S.T., Zhang,X.J., Xu,H. and Guo,A.G.
    Expression, purification, and activity identification of Alfimeprase in Pichia pastoris
    Protein Expr Purif (2007) 54, 240-246. PubMed  Europe PubMed DOI  E
    8. 2006
  8. Deitcher,S.R., Funk,W.D., Buchanan,J., Liu,S., Levy,M.D. and Toombs,C.F.
    Alfimeprase: a novel recombinant direct-acting fibrinolytic
    Expert Opin Biol Ther (2006) 6, 1361-1369. PubMed  Europe PubMed DOI
  9. Hong,T.T., Huang,J. and Lucchesi,B.R.
    Effect of thrombolysis on myocardial injury: recombinant tissue plasminogen activator vs. alfimeprase
    Am J Physiol Heart Circ Physiol (2006) 290, H959-H967. PubMed  Europe PubMed DOI  U
  10. Moll,S., Kenyon,P., Bertoli,L., De Maio,J., Homesley,H. and Deitcher,S.R.
    Phase II trial of alfimeprase, a novel-acting fibrin degradation agent, for occluded central venous access devices
    J Clin Oncol (2006) 24, 3056-3060. PubMed  Europe PubMed DOI
  11. Reddy,G.K.
    Clinical utility of novel agents in the treatment of central venous catheter occlusion
    Support Cancer Ther (2006) 3, 135-139. PubMed  Europe PubMed DOI  U
  12. Swenson,S. and Markland,F.S.
    Fibrolase
    Toxin Rev (2006) 25, 351-378.
    13. 2005
  13. Deitcher,S.R. and Toombs,C.F.
    Non-clinical and clinical characterization of a novel acting thrombolytic: alfimeprase
    Pathophysiol Haemost Thromb (2005) 34, 215-220. PubMed  Europe PubMed DOI
  14. Ouriel,K., Cynamon,J., Weaver,F.A., Dardik,H., Akers,D., Blebea,J., Gruneiro,L., Toombs,C.F., Wang-Clow,F., Mohler,M., Pena,L., Wan,C.Y. and Deitcher,S.R.
    A phase I trial of alfimeprase for peripheral arterial thrombolysis
    J Vasc Interv Radiol (2005) 16, 1075-1083. PubMed  Europe PubMed DOI  U
  15. Swenson,S. and Markland,F.S., Jr.
    Snake venom fibrin(ogen)olytic enzymes
    Toxicon (2005) 45, 1021-1039. PubMed  Europe PubMed DOI
    16. 2004
  16. Swenson,S., Markland,F.S., Jr. and Toombs,C.
    Fibrolase
    [ISSN:0-12-079610-4] (2004) 2, 640-643.  V
  17. Swenson,S., Toombs,C.F., Pena,L., Johansson,J. and Markland,F.S., Jr.
    Alpha-fibrinogenases
    Curr Drug Targets Cardiovasc Haematol Disord (2004) 4, 417-435. PubMed  Europe PubMed DOI
    18. 2003
  18. Ramos,O.H., Carmona,A.K. and Selistre-De-Araujo,H.S.
    Expression, refolding, and in vitro activation of a recombinant snake venom pro-metalloprotease
    Protein Expr Purif (2003) 28, 34-41. PubMed  Europe PubMed DOI  E
    19. 2001
  19. Bolger,M.B., Swenson,S. and Markland,F.S.J.
    Three-dimensional structure of fibrolase, the fibrinolytic enzyme from southern copperhead venom, modeled from the X-ray structure of adamalysin II and atrolysin C
    AAPS PharmSci (2001) 3, E16-E16. PubMed  Europe PubMed DOI  S
  20. Jones,G., Ronk,M., Mori,F. and Zhang,Z.
    Disulfide structure of alfimeprase: a recombinant analog of fibrolase
    Protein Sci (2001) 10, 1264-1267. PubMed  Europe PubMed DOI  PMC  EPMC
  21. Toombs,C.F.
    Alfimeprase: pharmacology of a novel fibrinolytic metalloproteinase for thrombolysis
    Haemostasis (2001) 31, 141-147. PubMed  Europe PubMed
    22. 2000
  22. Selistre-De-Araujo,H.S., de Souza,E.L., Beltramini,L.M., Ownby,C.L. and Souza,D.H.
    Expression, refolding, and activity of a recombinant nonhemorrhagic snake venom metalloprotease
    Protein Expr Purif (2000) 19, 41-47. PubMed  Europe PubMed DOI  E
  23. [YEAR:15-12-2000]Swenson,S., Bush,L.R. and Markland,F.S.
    Chimeric derivative of fibrolase, a fibrinolytic enzyme from southern copperhead venom, possesses inhibitory activity on platelet aggregation
    Arch Biochem Biophys (15-12-2000) 384, 227-237. PubMed  Europe PubMed DOI
    24. 1998
  24. Swenson,S. and Markland,F.S.
    PEGylation of fibrolase overcomes inhibition by alpha2-macroglobulin
    Fibrinolysis Proteolysis (1998) 12 Suppl. 1, 29-29.
    25. 1997
  25. Sanchez,E.F., Bush,L.R., Swenson,S. and Markland,F.S.
    Chimeric fibrolase: covalent attachment of an RGD-like peptide to create a potentially more effective thrombolytic agent
    Thromb Res (1997) 87, 289-302. PubMed  Europe PubMed DOI
    26. 1996
  26. Markland,F.S.
    Fibrolase, an active thrombolytic enzyme in arterial and venous thrombosis model systems
    Adv Exp Med Biol (1996) 391, 427-438. PubMed  Europe PubMed  U
    27. 1995
  27. Manning,M.C.
    Sequence analysis of fibrolase, a fibrinolytic metalloproteinase from Agkistrodon contortrix contortrix
    Toxicon (1995) 33, 1189-1200. PubMed  Europe PubMed DOI
  28. Selistre de Araujo,H.S. and Ownby,C.L.
    Molecular cloning and sequence analysis of cDNAs for metalloproteinases from broad-banded copperhead Agkistrodon contortrix laticinctus
    Arch Biochem Biophys (1995) 320, 141-148. PubMed  Europe PubMed DOI
    29. 1994
  29. Loayza,S.L., Trikha,M., Markland,F.S., Riquelme,P. and Kuo,J.
    Resolution of isoforms of natural and recombinant fibrolase, the fibrinolytic enzyme from Agkistrodon contortrix contortrix snake venom, and comparison of their EDTA sensitivities
    J Chromatogr B Biomed Appl (1994) 662, 227-243. PubMed  Europe PubMed DOI  I
  30. Retzios,A.D. and Markland,F.S.
    Fibrinolytic enzymes from the venoms of Agkistrodon contortrix contortrix and Crotalus basiliscus basiliscus: cleavage site specificity towards the alpha-chain of fibrin
    Thromb Res (1994) 74, 355-367. PubMed  Europe PubMed DOI  P
  31. Trikha,M., Schmitmeier,S. and Markland,F.S.
    Purification and characterization of fibrolase isoforms from venom of individual southern copperhead (Agkistrodon contortrix contortrix) snakes
    Toxicon (1994) 32, 1521-1531. PubMed  Europe PubMed
    32. 1993
  32. Patton,L.M., Pretzer,D., Schulteis,B.S., Saggart,B.S., Tennant,K.D. and Ahmed,N.K.
    Activity assays for characterizing the thrombolytic protein fibrolase
    J Biochem Biophys Methods (1993) 27, 11-23. PubMed  Europe PubMed DOI
  33. Pretzer,D., Schulteis,B.S., Smith,C.D., Vander Velde,D.G., Mitchell,J.W. and Manning,M.C.
    Fibrolase. A fibrinolytic protein from snake venom
    Pharm Biotechnol (1993) 5, 287-314. PubMed  Europe PubMed  V
    34. 1992
  34. Pretzer,D., Schulteis,B., Vander Velde,D.G., Smith,C.D., Mitchell,J.W. and Manning,M.C.
    Effect of zinc binding on the structure and stability of fibrolase, a fibrinolytic protein from snake venom
    Pharm Res (1992) 9, 870-877. PubMed  Europe PubMed DOI
  35. Randolph,A., Chamberlain,S.H., Chu,H.L., Retzios,A.D., Markland,F.S., Jr. and Masiarz,F.R.
    Amino acid sequence of fibrolase, a direct-acting fibrinolytic enzyme from Agkistrodon contortrix contortrix venom
    Protein Sci (1992) 1, 590-600. PubMed  Europe PubMed DOI  PMC  EPMC
    36. 1991
  36. Guan,A.L., Retzios,A.D., Henderson,G.N. and Markland,F.S., Jr.
    Purification and characterization of a fibrinolytic enzyme from venom of the southern copperhead snake (Agkistrodon contortrix contortrix)
    Arch Biochem Biophys (1991) 289, 197-207. PubMed  Europe PubMed
    37. 1988
  37. Retzios,A.D. and Markland,F.S., Jr.
    A direct-acting fibrinolytic enzyme from the venom of Agkistrodon contortrix contortrix: Effects on various components of the human blood coagulation and fibrinolysis systems
    Thromb Res (1988) 52, 541-552. PubMed  Europe PubMed
    38. 1982
  38. Bajwa,S.S., Kirakossian,H., Reddy,K.N. and Markland,F.S.
    Thrombin-like and fibrinolytic enzymes in the venoms from the Gaboon viper (Bitis gabonica), eastern cottonmouth moccasin (Agkistrodon p. piscivorus) and southern copperhead (Agkistrodon c. contortrix) snakes
    Toxicon (1982) 20, 427-432. PubMed  Europe PubMed

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