Merops Switch to
Inhibitors

Peptidase

Family Clan SEARCHES BLAST
MEROPS SUBMISSIONS

Other
information

Literature for peptidase M10.024: membrane-type matrix metallopeptidase-6

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

(Topics flags: P Specificity, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2016
  1. Soria-Valles,C., Gutierrez-Fernandez,A., Osorio,F.G., Carrero,D., Ferrando,A.A., Colado,E., Fernandez-Garcia,M.S., Bonzon-Kulichenko,E., Vazquez,J., Fueyo,A. and Lopez-Otin,C.<br>MMP-25 Metalloprotease regulates innate immune response through NF-kappaB signaling<br>J Immunol (2016) 197, 296-302. PubMed  Europe PubMed DOI
    2. 2012
  2. Pei,D.<br>Membrane-type matrix metalloproteinase 6<br>[ISSN:978-0-12-407744-7] (2012) 3, 828-830. DOI
  3. Starr,A.E., Bellac,C.L., Dufour,A., Goebeler,V. and Overall,C.M.<br>Biochemical characterization and N-terminomics analysis of leukolysin, the membrane-type 6 matrix metalloprotease (MMP25): chemokine and vimentin cleavages enhance cell migration and macrophage phagocytic activities<br>J Biol Chem (2012) 287, 13382-13395. PubMed  Europe PubMed DOI  P
    4. 2010
  4. Blumenthal,M.N., Zhong,W., Miller,M., Wendt,C., Connett,J.E. and Pei,D.<br>Serum metalloproteinase leukolysin (MMP-25/MT-6): a potential metabolic marker for atopy-associated inflammation<br>Clin Exp Allergy (2010) 40, 859-866. PubMed  Europe PubMed DOI
  5. Brown,G.D. and Nazarali,A.J.<br>Matrix metalloproteinase-25 has a functional role in mouse secondary palate development and is a downstream target of TGF-Beta3<br>BMC Dev Biol (2010) 10, 93-93. PubMed  Europe PubMed DOI
  6. Fortin,C.F., Sohail,A., Sun,Q., McDonald,P.P., Fridman,R. and Fulop,T.<br>MT6-MMP is present in lipid rafts and faces inward in living human PMNs but translocates to the cell surface during neutrophil apoptosis<br>Int Immunol (2010) 22, 637-649. PubMed  Europe PubMed DOI
    7. 2008
  7. Sohail,A., Sun,Q., Zhao,H., Bernardo,M.M., Cho,J.A. and Fridman,R.<br>MT4-(MMP17) and MT6-MMP (MMP25), a unique set of membrane-anchored matrix metalloproteinases: properties and expression in cancer<br>Cancer Metastasis Rev (2008) 27, 289-302. PubMed  Europe PubMed DOI
  8. Zhao,H., Sohail,A., Sun,Q., Shi,Q., Kim,S., Mobashery,S. and Fridman,R.<br>Identification and role of the homodimerization interface of the glycosylphosphatidylinositol-anchored membrane type 6 matrix metalloproteinase (MMP25)<br>J Biol Chem (2008) 283, 35023-35032. PubMed  Europe PubMed DOI  PMC  EPMC
    9. 2007
  9. Sun,Q., Weber,C.R., Sohail,A., Bernardo,M.M., Toth,M., Zhao,H., Turner,J.R. and Fridman,R.<br>MMP25 (MT6-MMP) is highly expressed in human colon cancer, promotes tumor growth, and exhibits unique biochemical properties<br>J Biol Chem (2007) 282, 21998-22010. PubMed  Europe PubMed DOI  PMC  EPMC
    10. 2004
  10. [YEAR:10-6-2004]Nie,J. and Pei,D.<br>Rapid inactivation of alpha-1-proteinase inhibitor by neutrophil specific leukolysin/membrane-type matrix metalloproteinase 6<br>Exp Cell Res (10-6-2004) 296, 145-150. PubMed  Europe PubMed DOI
  11. Pei,D.<br>Membrane-type matrix metalloproteinase 6<br>[ISSN:0-12-079610-4] (2004) 2, 557-558.  V
    12. 2003
  12. [YEAR:15-10-2003]Nie,J. and Pei,D.<br>Direct activation of pro-matrix metalloproteinase-2 by leukolysin/membrane-type 6 matrix metalloproteinase/matrix metalloproteinase 25 at the Asn(109)-Tyr bond<br>Cancer Res (15-10-2003) 63, 6758-6762. PubMed  Europe PubMed
    13. 2001
  13. Dong,Z., Katar,M., Alousi,S. and Berk,R.S.<br>Expression of membrane-type matrix metalloproteinases 4, 5, and 6 in mouse corneas infected with P. aeruginosa<br>Invest Ophthalmol Vis Sci (2001) 42, 3223-3227. PubMed  Europe PubMed
  14. [YEAR:23-2-2001]English,W.R., Velasco,G., Stracke,J.O., Knauper,V. and Murphy,G.<br>Catalytic activities of membrane-type 6 matrix metalloproteinase (MMP25)<br>FEBS Lett (23-2-2001) 491, 137-142. PubMed  Europe PubMed DOI
  15. [YEAR:15-6-2001]Kang,T., Yi,J., Guo,A., Wang,X., Overall,C.M., Jiang,W., Elde,R., Borregaard,N. and Pei,D.<br>Subcellular distribution and cytokine- and chemokine-regulated secretion of leukolysin/MT6-MMP/MMP-25 in neutrophils<br>J Biol Chem (15-6-2001) 276, 21960-21968. PubMed  Europe PubMed DOI
    16. 2000
  16. [YEAR:1-9-2000]Kojima,S., Itoh,Y., Matsumoto,S., Masuho,Y. and Seiki,M.<br>Membrane-type 6 matrix metalloproteinase (MT6-MMP, MMP-25) is the second glycosyl-phosphatidyl inositol (GPI)-anchored MMP<br>FEBS Lett (1-9-2000) 480, 142-146. PubMed  Europe PubMed DOI
  17. [YEAR:15-2-2000]Velasco,G., Cal,S., Merlos-Suarez,A., Ferrando,A.A., Alvarez,S., Nakano,A., Arribas,J. and Lopez-Otin,C.<br>Human MT6-matrix metalloproteinase: identification, progelatinase A activation, and expression in brain tumors<br>Cancer Res (15-2-2000) 60, 877-882. PubMed  Europe PubMed
    18. 1999
  18. Pei,D.<br>Leukolysin/MMP25/MT6-MMP: a novel matrix metalloproteinase specifically expressed in the leukocyte lineage<br>Cell Res (1999) 9, 291-303. PubMed  Europe PubMed DOI

feedback
Page created 8-September-2023

EMBL-EBI logo

© 2025 EBI
Terms of use