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Literature for peptidase M09.002: collagenase G/A (Clostridium histolyticum)

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: S Structure, A Assay, P Specificity, I Inhibitor, V Review, U Therapeutic. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Cevik,J., Rajaram,R., Pollock,M., Seth,I. and Rozen,M.
    Collagenase clostridium histolyticum for Dupuytren's disease: a comprehensive systematic review and comparative analysis against percutaneous needle aponeurotomy and limited fasciectomy
    J Plast Surg Hand Surg60, 27-34. PubMed  Europe PubMed DOI
    2. 2024
  2. Barrett,J.M. and Callaghan,J.P.
    Strain inhibition of bacterial collagenase is consistent with a collagen fibril uncrimping mechanism in rat tail tendons
    J Biomech162, 111892-111892. PubMed  Europe PubMed DOI
  3. Deng,Y., Herrmann,J., Wang,Y., Nguyen,M., Hall,J.K., Kim,J.H., Smith,M.L., Lutchen,K.R., Bartolak-Suki,E. and Suki,B.
    Physiological mechanical forces accelerate the degradation of bovine lung collagen fibers by bacterial collagenase
    Sci Rep14, 29008-29008. PubMed  Europe PubMed DOI
  4. Serwanja,J., Wieland,A.C., Haubenhofer,A., Brandstetter,H. and Schonauer,E.
    A conserved strategy to attack collagen: The activator domain in bacterial collagenases unwinds triple-helical collagen
    Proc Natl Acad Sci U S A121, e2321002121-e2321002121. PubMed  Europe PubMed DOI
    5. 2023
  5. Ansbacher,T., Tohar,R., Cohen,A., Cohen,O., Levartovsky,S., Arieli,A., Matalon,S., Bar,D.Z., Gal,M. and Weinberg,E.
    A novel computationally engineered collagenase reduces the force required for tooth extraction in an ex-situ porcine jaw model
    J Biol Eng17, 47-47. PubMed  Europe PubMed DOI
    6. 2022
  6. Alhayek,A., Khan,E.S., Schonauer,E., Dainghaus,T., Shafiei,R., Voos,K., Han,M.K.L., Ducho,C., Posselt,G., Wessler,S., Brandstetter,H., Haupenthal,J., Del Campo,A. and Hirsch,A.K.H.
    Inhibition of Collagenase Q1 of Bacillus cereus as a Novel Antivirulence Strategy for the Treatment of Skin-Wound Infections
    Adv Ther (Weinh)5, 2100222-2100222. PubMed  Europe PubMed DOI
  7. Alhayek,A., Abdelsamie,A.S., Schonauer,E., Camberlein,V., Hutterer,E., Posselt,G., Serwanja,J., Blochl,C., Huber,C.G., Haupenthal,J., Brandstetter,H., Wessler,S. and Hirsch,A.K.H.
    Discovery and Characterization of Synthesized and FDA-Approved Inhibitors of Clostridial and Bacillary Collagenases
    J Med Chem65, 12933-12955. PubMed  Europe PubMed DOI
    8. 2021
  8. Leontovyc,I., Koblas,T., Berkova,Z., Bittenglova,K., Leontovyc,A., Benesik,M. and Saudek,F.
    A Preliminary Characterization of a Novel Recombinant Clostridial Collagenase Blend
    Folia Biol (Praha)67, 82-89. PubMed  Europe PubMed
  9. Ziegelmann,M.J. and Yafi,F.A.
    Collagenase clostridium histolyticum is no longer available in Europe: what does this mean for our patients with Peyronie's Disease?
    Int J Impot Res33, 376-377. PubMed  Europe PubMed DOI
    10. 2020
  10. Cocci,A., Russo,G.I., Salamanca,J.I.M., Ralph,D., Palmieri,A. and Mondaini,N.
    The end of an era: withdrawal of Xiapex (Clostridium histolyticum collagenase) from the European market
    Eur Urol77, 660-661. PubMed  Europe PubMed DOI
  11. Passiatore,M., De Vitis,R. and Taccardo,G.
    Xiapex will no longer be distributed in Europe: our concerns and our hopes relative to collagenase
    Hand Surg Rehabil PubMed  Europe PubMed DOI
  12. Wei,D.H., Cantlon,M.B., Wakefield,D.B. and Vitale,M.A.
    Risk Factors for Skin Tears Following Collagenase Clostridium histolyticum to Treat Dupuytren Contractures
    J Hand Surg Am45, 989.e1-989.e10. PubMed  Europe PubMed DOI
    13. 2019
  13. O'Flanagan,C.H., Campbell,K.R., Zhang,A.W., Kabeer,F., Lim,J.L.P., Biele,J., Eirew,P., Lai,D., McPherson,A., Kong,E., Bates,C., Borkowski,K., Wiens,M., Hewitson,B., Hopkins,J., Pham,J., Ceglia,N., Moore,R., Mungall,A.J., McAlpine,J.N., Shah,S.P. and Aparicio,S.
    Dissociation of solid tumor tissues with cold active protease for single-cell RNA-seq minimizes conserved collagenase-associated stress responses
    Genome Biol20, 210-210. PubMed  Europe PubMed DOI
    14. 2018
  14. Caviness,P., Bauer,R., Tanaka,K., Janowska,K., Roeser,J.R., Harter,D., Sanders,J., Ruth,C., Matsushita,O. and Sakon,J.
    Ca(2+)-Induced orientation of tandem collagen binding domains from clostridial collagenase ColG permits two opposing functions of collagen fibril formation and retardation
    FEBS J285, 3254-3269. PubMed  Europe PubMed DOI
  15. Ganeshpurkar,A., Kumar,D. and Singh,S.K.
    Design, synthesis and collagenase inhibitory activity of some novel phenylglycine derivatives as metalloproteinase inhibitors
    Int J Biol Macromol107, 1491-1500. PubMed  Europe PubMed DOI  I
  16. Waycaster,C., Carter,M.J., Gilligan,A.M., Mearns,E.S., Fife,C.E. and Milne,C.T.
    Comparative cost and clinical effectiveness of clostridial collagenase ointment for chronic dermal ulcers
    J Comp Eff Res7, 149-165. PubMed  Europe PubMed DOI
    17. 2016
  17. Duarte,A.S., Correia,A. and Esteves,A.C.
    Bacterial collagenases - a review
    Crit Rev Microbiol42, 106-126. PubMed  Europe PubMed DOI  U
  18. Rafael,S.C., Diego,G.H. and Javier,C.H.F.
    Mechanism of action of collagenase clostridium histolyticum for clinical application
    European j clin pharm18, 263-272.  V
  19. Shima,H., Inagaki,A., Imura,T., Yamagata,Y., Watanabe,K., Igarashi,K., Goto,M. and Murayama,K.
    Collagen V is a potential substrate for clostridial collagenase G in pancreatic islet isolation
    J Diabetes Res2016, 4396756-4396756. PubMed  Europe PubMed DOI
  20. Verstreken,F., Degreef,I., Decramer,A., Libberecht,K., Vanhove,W., Datco,A., Vanhaecke,J., Clermont,D. and Duerinckx,J.
    Effectiveness and safety of collagenase Clostridium histolyticum in Dupuytren's disease: an observational study in Belgium
    Acta Orthop Belg82, 405-411.  U
  21. Watanabe-Nakayama,T., Itami,M., Kodera,N., Ando,T. and Konno,H.
    High-speed atomic force microscopy reveals strongly polarized movement of clostridial collagenase along collagen fibrils
    Sci Rep6, 28975-28975. PubMed  Europe PubMed DOI
    22. 2015
  22. McCallon,S.K. and Frilot,C.
    A retrospective study of the effects of clostridial collagenase ointment and negative pressure wound therapy for the treatment of chronic pressure ulcers
    Wounds27, 44-53. PubMed  Europe PubMed  U
  23. Motley,T.A., Gilligan,A.M., Lange,D.L., Waycaster,C.R. and Dickerson,J.E., Jr.
    Cost-effectiveness of clostridial collagenase ointment on wound closure in patients with diabetic foot ulcers: economic analysis of results from a multicenter, randomized, open-label trial
    J Foot Ankle Res8, 7-7. PubMed  Europe PubMed DOI  U
  24. Peimer,C.A., Wilbrand,S., Gerber,R.A., Chapman,D. and Szczypa,P.P.
    Safety and tolerability of collagenase Clostridium histolyticum and fasciectomy for Dupuytren's contracture
    J Hand Surg Eur Vol40, 141-149. PubMed  Europe PubMed DOI  U
  25. Velmurugan,P., Jonnalagadda,R.R. and Unni Nair,B.
    Engineering D-amino acid containing collagen like peptide at the cleavage site of Clostridium histolyticum collagenase for its inhibition
    PLoS ONE10, e0124398- PubMed  Europe PubMed DOI
  26. Verheyden,J.R.
    Early outcomes of a sequential series of 144 patients with Dupuytren's contracture treated by collagenase injection using an increased dose, multi-cord technique
    J Hand Surg Eur Vol40, 133-140. PubMed  Europe PubMed DOI  U
  27. Warwick,D., Arner,M., Pajardi,G., Reichert,B., Szabo,Z., Masmejean,E.H., Fores,J., Chapman,D.S., Gerber,R.A., Huard,F., Seghouani,A. and Szczypa,P.P.
    Collagenase Clostridium histolyticum in patients with Dupuytren's contracture: results from POINT X, an open-label study of clinical and patient-reported outcomes
    J Hand Surg Eur Vol40, 124-132. PubMed  Europe PubMed DOI  U
  28. Yang,K.K. and Bennett,N.
    The history of collagenase Clostridium histolyticum
    Sex Med Rev3, 289-297. PubMed  Europe PubMed DOI  U
  29. Zhang,D., Zhang,Y., Wang,Z., Zhang,X. and Sheng,M.
    Target radiofrequency combined with collagenase chemonucleolysis in the treatment of lumbar intervertebral disc herniation
    Int J Clin Exp Med8, 526-532. PubMed  Europe PubMed  U
  30. Zhang,Y.Z., Ran,L.Y., Li,C.Y. and Chen,X.L.
    Diversity, structures, and collagen-degrading mechanisms of bacterial collagenolytic proteases
    Appl Environ Microbiol81, 6098-6107. PubMed  Europe PubMed DOI  V
    31. 2014
  31. Alberton,F., Corain,M., Garofano,A., Pangallo,L., Valore,A., Zanella,V. and Adani,R.
    Efficacy and safety of collagenase Clostridium histolyticum injection for Dupuytren contracture: report of 40 cases
    Musculoskelet Surg98, 225-232. PubMed  Europe PubMed DOI  U
  32. Eckhard,U., Huesgen,P.F., Brandstetter,H. and Overall,C.M.
    Proteomic protease specificity profiling of clostridial collagenases reveals their intrinsic nature as dedicated degraders of collagen
    J Proteomics100, 102-114. PubMed  Europe PubMed DOI  P
  33. Tokmina-Roszyk,M., Tokmina-Roszyk,D., Bhowmick,M. and Fields,G.B.
    Development of a Forster resonance energy transfer assay for monitoring bacterial collagenase triple-helical peptidase activity
    Anal Biochem453, 61-69. PubMed  Europe PubMed DOI  A
    34. 2013
  34. Eckhard,U., Schonauer,E. and Brandstetter,H.
    Structural basis for activity regulation and substrate preference of clostridial collagenases G, H, and T
    J Biol Chem288, 20184-20194. PubMed  Europe PubMed DOI  S
  35. Gelbard,M., Goldstein,I., Hellstrom,W.J., McMahon,C.G., Smith,T., Tursi,J., Jones,N., Kaufman,G.J. and Carson,C.C., III
    Clinical efficacy, safety and tolerability of collagenase clostridium histolyticum for the treatment of peyronie disease in 2 large double-blind, randomized, placebo controlled phase 3 studies
    J Urol190, 199-207. PubMed  Europe PubMed DOI  U
  36. Oshima,N., Narukawa,Y., Takeda,T. and Kiuchi,F.
    Collagenase inhibitors from Viola yedoensis
    J Nat Med67, 240-245. PubMed  Europe PubMed DOI  I
  37. Peimer,C.A., Skodny,P. and Mackowiak,J.I.
    Collagenase clostridium histolyticum for Dupuytren contracture: Patterns of use and effectiveness in clinical practice
    J Hand Surg Am38, 2370-2376. PubMed  Europe PubMed DOI  U
  38. Witthaut,J., Jones,G., Skrepnik,N., Kushner,H., Houston,A. and Lindau,T.R.
    Efficacy and safety of collagenase clostridium histolyticum injection for Dupuytren contracture: short-term results from 2 open-label studies
    J Hand Surg Am38, 2-11. PubMed  Europe PubMed DOI  U
    39. 2012
  39. Adhikari,A.S., Glassey,E. and Dunn,A.R.
    Conformational dynamics accompanying the proteolytic degradation of trimeric collagen I by collagenases
    J Am Chem Soc134, 13259-13265. PubMed  Europe PubMed DOI
  40. Balamurugan,A.N., Loganathan,G., Bellin,M.D., Wilhelm,J.J., Harmon,J., Anazawa,T., Soltani,S.M., Radosevich,D.M., Yuasa,T., Tiwari,M., Papas,K.K., McCarthy,R., Sutherland,D.E. and Hering,B.J.
    A new enzyme mixture to increase the yield and transplant rate of autologous and allogeneic human islet products
    Transplantation93, 693-702. PubMed  Europe PubMed DOI
  41. Rozen,W.M., Edirisinghe,Y. and Crock,J.
    Late complications of clinical Clostridium histolyticum collagenase use in Dupuytren's disease
    PLoS ONE7, e43406-e43406. PubMed  Europe PubMed DOI
  42. Sides,C.R., Liyanage,R., Lay,J.O., Jr., Philominathan,S.T., Matsushita,O. and Sakon,J.
    Probing the 3-D structure, dynamics, and stability of bacterial collagenase collagen binding domain (apo- versus holo-) by limited proteolysis MALDI-TOF MS
    J Am Soc Mass Spectrom23, 505-519. PubMed  Europe PubMed DOI
  43. Syed,F., Thomas,A.N., Singh,S., Kolluru,V., Emeigh Hart,S.G. and Bayat,A.
    In vitro study of novel collagenase (XIAFLEX(R)) on Dupuytren's disease fibroblasts displays unique drug related properties
    PLoS ONE7, e31430-e31430. PubMed  Europe PubMed DOI  U
  44. Van Wart,H.E.
    Clostridium collagenases
    [ISSN:978-0-12-407744-7]3, 607-611. DOI
    45. 2011

  45. Collagenase clostridium histolyticum. Short-term benefit in Dupuytren's contracture, unknown long-term risks
    Prescrire Int20, 285-287. PubMed  Europe PubMed  U
  46. Aysan,E., Bektas,H., Ersoz,F. and Behzat,K.
    Role of single-dose clostridiopeptidase A collagenase in peritoneal adhesions
    Eur Surg Res47, 130-134. PubMed  Europe PubMed DOI  U
  47. Eckhard,U., Schonauer,E., Nuss,D. and Brandstetter,H.
    Structure of collagenase G reveals a chew-and-digest mechanism of bacterial collagenolysis
    Nat Struct Mol Biol18, 1109-1114. PubMed  Europe PubMed DOI  S
  48. Holzer,L. and Holzer,G.
    [Collagenase clostridum histolyticum in the management of Dupuytren's contracture]
    Handchir Mikrochir Plast Chir43, 269-274. PubMed  Europe PubMed DOI  U
  49. Kaplan,F.T.
    Collagenase clostridium histolyticum injection for the treatment of Dupuytren's contracture
    Drugs Today (Barc)47, 653-667. PubMed  Europe PubMed DOI  U
  50. Karagol,B.S., Okumus,N., Dursun,A., Karadag,N. and Zenciroglu,A.
    Early and successful enzymatic debridement via collagenase application to pinna in a preterm neonate
    Pediatr Dermatol28, 600-601. PubMed  Europe PubMed DOI  U
  51. Wang,Y., Paushter,D., Wang,S., Barbaro,B., Harvat,T., Danielson,K.K., Kinzer,K., Zhang,L., Qi,M. and Oberholzer,J.
    Highly purified versus filtered crude collagenase: comparable human islet isolation outcomes
    Cell Transplant20, 1817-1825. PubMed  Europe PubMed DOI
  52. Watt,A.J. and Hentz,V.R.
    Collagenase clostridium histolyticum: a novel nonoperative treatment for Dupuytren's disease
    Int J Clin Rheumatol6, 123-133. DOI  U
    53. 2010
  53. Gilpin,D., Coleman,S., Hall,S., Houston,A., Karrasch,J. and Jones,N.
    Injectable collagenase Clostridium histolyticum: a new nonsurgical treatment for Dupuytren's disease
    J Hand Surg Am35, 2027-2038. PubMed  Europe PubMed DOI  U
  54. Nikolic,D.M., Djordjevic,P.B., Sreckovic,V.D., Paunovic,I., Kalezic,N., Popovic,S., Nikolic,B. and Stefanovic,D.
    Comparative analysis of collagenase XI and liberase H1 for the isolation of human pancreatic islets
    Hepatogastroenterology57, 1573-1578. PubMed  Europe PubMed
  55. Shi,L., Ermis,R., Garcia,A., Telgenhoff,D. and Aust,D.
    Degradation of human collagen isoforms by Clostridium collagenase and the effects of degradation products on cell migration
    Int Wound J7, 87-95. PubMed  Europe PubMed DOI
  56. Singh,J., Singh,K., Shaik,B., Singh,N. and Agrawal,V.K.
    QSAR studies on some protease inhibitors incorporating sulphonyl-l-alanine hydroxamate moieties
    Oxid Commun33, 631-651.  I
  57. Spiriti,J. and van der Vaart,A.
    Mechanism of the calcium-induced trans-cis isomerization of a non-prolyl peptide bond in Clostridium histolyticum collagenase
    Biochemistry49, 5314-5320. PubMed  Europe PubMed DOI
  58. Thomas,A. and Bayat,A.
    The emerging role of Clostridium histolyticum collagenase in the treatment of Dupuytren disease
    Ther Clin Risk Manag6, 557-572. PubMed  Europe PubMed DOI  U
  59. Watt,A.J., Curtin,C.M. and Hentz,V.R.
    Collagenase injection as nonsurgical treatment of Dupuytren's disease: 8-year follow-up
    J Hand Surg Am35, 534-539. PubMed  Europe PubMed DOI  U
    60. 2009
  60. Philominathan,S.T., Koide,T., Hamada,K., Yasui,H., Seifert,S., Matsushita,O. and Sakon,J.
    Unidirectional binding of clostridial collagenase to triple helical substrates
    J Biol Chem284, 10868-10876. PubMed  Europe PubMed DOI
  61. Philominathan,S.T., Matsushita,O., Gensure,R. and Sakon,J.
    Ca2+-induced linker transformation leads to a compact and rigid collagen-binding domain of Clostridium histolyticum collagenase
    FEBS J276, 3589-3601. PubMed  Europe PubMed DOI
    62. 2008
  62. Eckhard,U., Nuss,D., Ducka,P., Schonauer,E. and Brandstetter,H.
    Crystallization and preliminary X-ray characterization of the catalytic domain of collagenase G from Clostridium histolyticum
    Acta Crystallograph Sect F Struct Biol Cryst Commun64, 419-421. PubMed  Europe PubMed DOI
  63. Saikumari,Y.K. and Balaram,P.
    An internally quenched fluorescent substrate for collagenase
    Biopolymers90, 131-137. PubMed  Europe PubMed DOI  A
    64. 2007
  64. Antonioli,B., Fermo,I., Cainarca,S., Marzorati,S., Nano,R., Baldissera,M., Bachi,A., Paroni,R., Ricordi,C. and Bertuzzi,F.
    Characterization of collagenase blend enzymes for human islet transplantation
    Transplantation84, 1568-1575. PubMed  Europe PubMed DOI
    65. 2005
  65. [YEAR:27-9-2005]Barnett,M.J., Zhai,X., LeGatt,D.F., Cheng,S.B., Shapiro,A.M. and Lakey,J.R.
    Quantitative assessment of collagenase blends for human islet isolation
    Transplantation80, 723-728. PubMed  Europe PubMed DOI
  66. Brandhorst,D., Huettler,S., Alt,A., Raemsch-Guenther,N., Kurfuerst,M., Bretzel,R.G. and Brandhorst,H.
    Adjustment of the ratio between collagenase class II and I improves islet isolation outcome
    Transplant Proc37, 3450-3451. PubMed  Europe PubMed DOI
    67. 2004
  67. Van Wart,H.E.
    Clostridial collagenases
    [ISSN:0-12-079610-4]2, 416-419.  V
    68. 2002
  68. [YEAR:8-3-2002]Hu,Y., Webb,E., Singh,J., Morgan,B.A., Gainor,J.A., Gordon,T.D. and Siahaan,T.J.
    Rapid determination of substrate specificity of Clostridium histolyticum beta-collagenase using an immobilized peptide library
    J Biol Chem277, 8366-8371. PubMed  Europe PubMed DOI
    69. 2001
  69. [YEAR:21-6-2001]Clare,B.W., Scozzafava,A. and Supuran,C.T.
    Protease inhibitors: Synthesis of a series of bacterial collagenase inhibitors of the sulfonyl amino acyl hydroxamate type
    J Med Chem44, 2253-2258. PubMed  Europe PubMed DOI  I
  70. [YEAR:23-3-2001]Matsushita,O., Koide,T., Kobayashi,R., Nagata,K. and Okabe,A.
    Substrate recognition by the collagen-binding domain of Clostridium histolyticum class I collagenase
    J Biol Chem276, 8761-8770. PubMed  Europe PubMed DOI
    71. 2000
  71. Awad,M.M., Ellemor,D.M., Bryant,A.E., Matsushita,O., Boyd,R.L., Stevens,D.L., Emmins,J.J. and Rood,J.I.
    Construction and virulence testing of a collagenase mutant of Clostridium perfringens
    Microb Pathog28, 107-117. PubMed  Europe PubMed DOI
  72. [YEAR:4-5-2000]Scozzafava,A. and Supuran,C.T.
    Protease inhibitors: synthesis of potent bacterial collagenase and matrix metalloproteinase inhibitors incorporating N-4-nitrobenzylsulfonylglycine hydroxamate moieties
    J Med Chem43, 1858-1865. PubMed  Europe PubMed DOI  I
  73. [YEAR:6-3-2000]Scozzafava,A. and Supuran,C.T.
    Protease inhibitors: Synthesis of Clostridium histolyticum collagenase inhibitors incorporating sulfonyl-L-alanine hydroxamate moieties
    Bioorg Med Chem Lett10, 499-502. PubMed  Europe PubMed DOI  I
  74. Supuran,C.T., Briganti,F., Mincione,G. and Scozzafava,A.
    Protease inhibitors: synthesis of L-alanine hydroxamate sulfonylated derivatives as inhibitors of Clostridium histolyticum collagenase
    J Enzyme Inhib15, 111-128. PubMed  Europe PubMed  I
    75. 1999
  75. Matsushita,O., Jung,C.M., Katayama,S., Minami,J., Takahashi,Y. and Okabe,A.
    Gene duplication and multiplicity of collagenases in Clostridium histolyticum
    J Bacteriol181, 923-933. PubMed  Europe PubMed
    76. 1998
  76. [YEAR:6-2-1998]Matsushita,O., Jung,C.M., Minami,J., Katayama,S., Nishi,N. and Okabe,A.
    A study of the collagen-binding domain of a 116-kDa Clostridium histolyticum collagenase
    J Biol Chem273, 3643-3648. PubMed  Europe PubMed DOI
    77. 1997
  77. Ohtani,K., Bando,M., Swe,T., Banu,S., Oe,M., Hayashi,H. and Shimizu,T.
    Collagenase gene (colA) is located in the 3'-flanking region of the perfringolysin O (pfoA) locus in Clostridium perfringens
    FEMS Microbiol Lett146, 155-159. PubMed  Europe PubMed DOI
    78. 1995
  78. Wolters,G.H., Vos-Scheperkeuter,G.H., Lin,H.C. and van Schilfgaarde,R.
    Different roles of class I and class II Clostridium histolyticum collagenase in rat pancreatic islet isolation
    Diabetes44, 227-233. PubMed  Europe PubMed
    79. 1994
  79. Matsushita,O., Yoshihara,K., Katayama,S., Minami,J. and Okabe,A.
    Purification and characterization of Clostridium perfringens 120-kilodalton collagenase and nucleotide sequence of the corresponding gene
    J Bacteriol176, 149-156. PubMed  Europe PubMed
    80. 1992
  80. French,M.F., Bhown,A. and Van Wart,H.E.
    Identification of Clostridium histolyticum collagenase hyperreactive sites in type I, II, and III collagens: lack of correlation with local triple helical stability
    J Protein Chem11, 83-97. PubMed  Europe PubMed
  81. Hedtmann,A., Fett,H., Steffen,R. and Kramer,J.
    [Chemonucleolysis using chymopapain and collagenase. 3-year results of a prospective randomized study]
    Z Orthop Ihre Grenzgeb130, 36-44. PubMed  Europe PubMed DOI
  82. Mallya,S.K., Mookhtiar,K.A. and Van Wart,H.E.
    Kinetics of hydrolysis of type I, II, and III collagens by the class I and II Clostridium histolyticum collagenases
    J Protein Chem11, 99-107. PubMed  Europe PubMed
  83. Mookhtiar,K.A. and Van Wart,H.E.
    Clostridium histolyticum collagenases: a new look at some old enzymes
    Matrix Suppl1, 116-126. PubMed  Europe PubMed
  84. Schwartz,M.A. and Van Wart,H.E.
    Synthetic inhibitors of bacterial and mammalian interstitial collagenases
    Prog Med Chem29, 271-334. PubMed  Europe PubMed DOI  I
    85. 1990
  85. Dive,V., Yiotakis,A., Nicolaou,A. and Toma,F.
    Inhibition of Clostridium histolyticum collagenases by phosphonamide peptide inhibitors
    Eur J Biochem191, 685-693. PubMed  Europe PubMed DOI  I
    86. 1989
  86. Barrett,A.J., Knight,C.G., Brown,M.A. and Tisljar,U.
    A continuous fluorimetric assay for clostridial collagenase and Pz-peptidase activity
    Biochem J260, 259-263. PubMed  Europe PubMed
    87. 1988
  87. [YEAR:20-9-1988]Angleton,E.L. and Van Wart,H.E.
    Preparation and reconstitution with divalent metal ions of class I and class II Clostridium histolyticum apocollagenases
    Biochemistry27, 7406-7412. PubMed  Europe PubMed
  88. [YEAR:20-9-1988]Angleton,E.L. and Van Wart,H.E.
    Preparation by direct metal exchange and kinetic study of active site metal substituted class I and class II Clostridium histolyticum collagenases
    Biochemistry27, 7413-7418. PubMed  Europe PubMed
  89. Mookhtiar,K.A., Grobelny,D., Galardy,R.E. and Van Wart,H.E.
    Ketone-substrate analogues of Clostridium histolyticum collagenases: tight-binding transition-state analogue inhibitors
    Biochemistry27, 4299-4304. PubMed  Europe PubMed  I
  90. Yiotakis,A., Hatgiyannacou,A., Dive,V. and Toma,F.
    New thiol inhibitors of Clostridium histolyticum collagenase: importance of the P3' position
    Eur J Biochem172, 764-766. DOI  I
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