Literature for peptidase M09.002: collagenase G/A (Clostridium histolyticum)

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: S Structure, A Assay, P Specificity, I Inhibitor, V Review, U Therapeutic. To select only the references relevant to a single topic, click the link above. See explanation.)

2025

Cevik,J., Rajaram,R., Pollock,M., Seth,I. and Rozen,M. Collagenase clostridium histolyticum for Dupuytren's disease: a comprehensive systematic review and comparative analysis against percutaneous needle aponeurotomy and limited fasciectomy J Plast Surg Hand Surg (2025) 60, 27-34. PubMed Europe PubMed DOI
Zhu,S., Mi,J., Sun,J., Yao,J. and Huang,H. Discovery and characterization a new collagenase from Hathewaya massiliensis for effective subcutaneous adipolysis Bioorg Med Chem Lett (2025) 128, 130324-130324. PubMed Europe PubMed DOI

2024

Barrett,J.M. and Callaghan,J.P. Strain inhibition of bacterial collagenase is consistent with a collagen fibril uncrimping mechanism in rat tail tendons J Biomech (2024) 162, 111892-111892. PubMed Europe PubMed DOI
Deng,Y., Herrmann,J., Wang,Y., Nguyen,M., Hall,J.K., Kim,J.H., Smith,M.L., Lutchen,K.R., Bartolak-Suki,E. and Suki,B. Physiological mechanical forces accelerate the degradation of bovine lung collagen fibers by bacterial collagenase Sci Rep (2024) 14, 29008-29008. PubMed Europe PubMed DOI PMC EPMC
Serwanja,J., Wieland,A.C., Haubenhofer,A., Brandstetter,H. and Schonauer,E. A conserved strategy to attack collagen: The activator domain in bacterial collagenases unwinds triple-helical collagen Proc Natl Acad Sci U S A (2024) 121, e2321002121-e2321002121. PubMed Europe PubMed DOI PMC EPMC

2023

Ansbacher,T., Tohar,R., Cohen,A., Cohen,O., Levartovsky,S., Arieli,A., Matalon,S., Bar,D.Z., Gal,M. and Weinberg,E. A novel computationally engineered collagenase reduces the force required for tooth extraction in an ex-situ porcine jaw model J Biol Eng (2023) 17, 47-47. PubMed Europe PubMed DOI PMC EPMC

2022

Alhayek,A., Abdelsamie,A.S., Schonauer,E., Camberlein,V., Hutterer,E., Posselt,G., Serwanja,J., Blochl,C., Huber,C.G., Haupenthal,J., Brandstetter,H., Wessler,S. and Hirsch,A.K.H. Discovery and Characterization of Synthesized and FDA-Approved Inhibitors of Clostridial and Bacillary Collagenases J Med Chem (2022) 65, 12933-12955. PubMed Europe PubMed DOI PMC EPMC
Alhayek,A., Khan,E.S., Schonauer,E., Dainghaus,T., Shafiei,R., Voos,K., Han,M.K.L., Ducho,C., Posselt,G., Wessler,S., Brandstetter,H., Haupenthal,J., Del Campo,A. and Hirsch,A.K.H. Inhibition of Collagenase Q1 of Bacillus cereus as a Novel Antivirulence Strategy for the Treatment of Skin-Wound Infections Adv Ther (Weinh) (2022) 5, 2100222-2100222. PubMed Europe PubMed DOI PMC EPMC

2021

Leontovyc,I., Koblas,T., Berkova,Z., Bittenglova,K., Leontovyc,A., Benesik,M. and Saudek,F. A Preliminary Characterization of a Novel Recombinant Clostridial Collagenase Blend Folia Biol (Praha) (2021) 67, 82-89. PubMed Europe PubMed
Ziegelmann,M.J. and Yafi,F.A. Collagenase clostridium histolyticum is no longer available in Europe: what does this mean for our patients with Peyronie's Disease? Int J Impot Res (2021) 33, 376-377. PubMed Europe PubMed DOI

2020

Cocci,A., Russo,G.I., Salamanca,J.I.M., Ralph,D., Palmieri,A. and Mondaini,N. The end of an era: withdrawal of Xiapex (Clostridium histolyticum collagenase) from the European market Eur Urol (2020) 77, 660-661. PubMed Europe PubMed DOI
Passiatore,M., De Vitis,R. and Taccardo,G. Xiapex will no longer be distributed in Europe: our concerns and our hopes relative to collagenase Hand Surg Rehabil (2020) PubMed Europe PubMed DOI
Wei,D.H., Cantlon,M.B., Wakefield,D.B. and Vitale,M.A. Risk Factors for Skin Tears Following Collagenase Clostridium histolyticum to Treat Dupuytren Contractures J Hand Surg Am (2020) 45, 989.e1-989.e10. PubMed Europe PubMed DOI

2019

O'Flanagan,C.H., Campbell,K.R., Zhang,A.W., Kabeer,F., Lim,J.L.P., Biele,J., Eirew,P., Lai,D., McPherson,A., Kong,E., Bates,C., Borkowski,K., Wiens,M., Hewitson,B., Hopkins,J., Pham,J., Ceglia,N., Moore,R., Mungall,A.J., McAlpine,J.N., Shah,S.P. and Aparicio,S. Dissociation of solid tumor tissues with cold active protease for single-cell RNA-seq minimizes conserved collagenase-associated stress responses Genome Biol (2019) 20, 210-210. PubMed Europe PubMed DOI PMC EPMC

2018

Caviness,P., Bauer,R., Tanaka,K., Janowska,K., Roeser,J.R., Harter,D., Sanders,J., Ruth,C., Matsushita,O. and Sakon,J. Ca(2+)-Induced orientation of tandem collagen binding domains from clostridial collagenase ColG permits two opposing functions of collagen fibril formation and retardation FEBS J (2018) 285, 3254-3269. PubMed Europe PubMed DOI
Ganeshpurkar,A., Kumar,D. and Singh,S.K. Design, synthesis and collagenase inhibitory activity of some novel phenylglycine derivatives as metalloproteinase inhibitors Int J Biol Macromol (2018) 107, 1491-1500. PubMed Europe PubMed DOI I
Waycaster,C., Carter,M.J., Gilligan,A.M., Mearns,E.S., Fife,C.E. and Milne,C.T. Comparative cost and clinical effectiveness of clostridial collagenase ointment for chronic dermal ulcers J Comp Eff Res (2018) 7, 149-165. PubMed Europe PubMed DOI

2016

Duarte,A.S., Correia,A. and Esteves,A.C. Bacterial collagenases - a review Crit Rev Microbiol (2016) 42, 106-126. PubMed Europe PubMed DOI U
Rafael,S.C., Diego,G.H. and Javier,C.H.F. Mechanism of action of collagenase clostridium histolyticum for clinical application European j clin pharm (2016) 18, 263-272. V
Shima,H., Inagaki,A., Imura,T., Yamagata,Y., Watanabe,K., Igarashi,K., Goto,M. and Murayama,K. Collagen V is a potential substrate for clostridial collagenase G in pancreatic islet isolation J Diabetes Res (2016) 2016, 4396756-4396756. PubMed Europe PubMed DOI PMC EPMC
Verstreken,F., Degreef,I., Decramer,A., Libberecht,K., Vanhove,W., Datco,A., Vanhaecke,J., Clermont,D. and Duerinckx,J. Effectiveness and safety of collagenase Clostridium histolyticum in Dupuytren's disease: an observational study in Belgium Acta Orthop Belg (2016) 82, 405-411. U
Watanabe-Nakayama,T., Itami,M., Kodera,N., Ando,T. and Konno,H. High-speed atomic force microscopy reveals strongly polarized movement of clostridial collagenase along collagen fibrils Sci Rep (2016) 6, 28975-28975. PubMed Europe PubMed DOI PMC EPMC

2015

McCallon,S.K. and Frilot,C. A retrospective study of the effects of clostridial collagenase ointment and negative pressure wound therapy for the treatment of chronic pressure ulcers Wounds (2015) 27, 44-53. PubMed Europe PubMed U
Motley,T.A., Gilligan,A.M., Lange,D.L., Waycaster,C.R. and Dickerson,J.E., Jr. Cost-effectiveness of clostridial collagenase ointment on wound closure in patients with diabetic foot ulcers: economic analysis of results from a multicenter, randomized, open-label trial J Foot Ankle Res (2015) 8, 7-7. PubMed Europe PubMed DOI PMC EPMC U
Peimer,C.A., Wilbrand,S., Gerber,R.A., Chapman,D. and Szczypa,P.P. Safety and tolerability of collagenase Clostridium histolyticum and fasciectomy for Dupuytren's contracture J Hand Surg Eur Vol (2015) 40, 141-149. PubMed Europe PubMed DOI U
Velmurugan,P., Jonnalagadda,R.R. and Unni Nair,B. Engineering D-amino acid containing collagen like peptide at the cleavage site of Clostridium histolyticum collagenase for its inhibition PLoS ONE (2015) 10, e0124398- PubMed Europe PubMed DOI
Verheyden,J.R. Early outcomes of a sequential series of 144 patients with Dupuytren's contracture treated by collagenase injection using an increased dose, multi-cord technique J Hand Surg Eur Vol (2015) 40, 133-140. PubMed Europe PubMed DOI U
Warwick,D., Arner,M., Pajardi,G., Reichert,B., Szabo,Z., Masmejean,E.H., Fores,J., Chapman,D.S., Gerber,R.A., Huard,F., Seghouani,A. and Szczypa,P.P. Collagenase Clostridium histolyticum in patients with Dupuytren's contracture: results from POINT X, an open-label study of clinical and patient-reported outcomes J Hand Surg Eur Vol (2015) 40, 124-132. PubMed Europe PubMed DOI U
Yang,K.K. and Bennett,N. The history of collagenase Clostridium histolyticum Sex Med Rev (2015) 3, 289-297. PubMed Europe PubMed DOI U
Zhang,D., Zhang,Y., Wang,Z., Zhang,X. and Sheng,M. Target radiofrequency combined with collagenase chemonucleolysis in the treatment of lumbar intervertebral disc herniation Int J Clin Exp Med (2015) 8, 526-532. PubMed Europe PubMed PMC EPMC U
Zhang,Y.Z., Ran,L.Y., Li,C.Y. and Chen,X.L. Diversity, structures, and collagen-degrading mechanisms of bacterial collagenolytic proteases Appl Environ Microbiol (2015) 81, 6098-6107. PubMed Europe PubMed DOI V

2014

Alberton,F., Corain,M., Garofano,A., Pangallo,L., Valore,A., Zanella,V. and Adani,R. Efficacy and safety of collagenase Clostridium histolyticum injection for Dupuytren contracture: report of 40 cases Musculoskelet Surg (2014) 98, 225-232. PubMed Europe PubMed DOI U
Eckhard,U., Huesgen,P.F., Brandstetter,H. and Overall,C.M. Proteomic protease specificity profiling of clostridial collagenases reveals their intrinsic nature as dedicated degraders of collagen J Proteomics (2014) 100, 102-114. PubMed Europe PubMed DOI P
Tokmina-Roszyk,M., Tokmina-Roszyk,D., Bhowmick,M. and Fields,G.B. Development of a Forster resonance energy transfer assay for monitoring bacterial collagenase triple-helical peptidase activity Anal Biochem (2014) 453, 61-69. PubMed Europe PubMed DOI A

2013

Eckhard,U., Schonauer,E. and Brandstetter,H. Structural basis for activity regulation and substrate preference of clostridial collagenases G, H, and T J Biol Chem (2013) 288, 20184-20194. PubMed Europe PubMed DOI PMC EPMC S
Gelbard,M., Goldstein,I., Hellstrom,W.J., McMahon,C.G., Smith,T., Tursi,J., Jones,N., Kaufman,G.J. and Carson,C.C., III Clinical efficacy, safety and tolerability of collagenase clostridium histolyticum for the treatment of peyronie disease in 2 large double-blind, randomized, placebo controlled phase 3 studies J Urol (2013) 190, 199-207. PubMed Europe PubMed DOI U
Oshima,N., Narukawa,Y., Takeda,T. and Kiuchi,F. Collagenase inhibitors from Viola yedoensis J Nat Med (2013) 67, 240-245. PubMed Europe PubMed DOI I
Peimer,C.A., Skodny,P. and Mackowiak,J.I. Collagenase clostridium histolyticum for Dupuytren contracture: Patterns of use and effectiveness in clinical practice J Hand Surg Am (2013) 38, 2370-2376. PubMed Europe PubMed DOI U
Witthaut,J., Jones,G., Skrepnik,N., Kushner,H., Houston,A. and Lindau,T.R. Efficacy and safety of collagenase clostridium histolyticum injection for Dupuytren contracture: short-term results from 2 open-label studies J Hand Surg Am (2013) 38, 2-11. PubMed Europe PubMed DOI U

2012

Adhikari,A.S., Glassey,E. and Dunn,A.R. Conformational dynamics accompanying the proteolytic degradation of trimeric collagen I by collagenases J Am Chem Soc (2012) 134, 13259-13265. PubMed Europe PubMed DOI
Balamurugan,A.N., Loganathan,G., Bellin,M.D., Wilhelm,J.J., Harmon,J., Anazawa,T., Soltani,S.M., Radosevich,D.M., Yuasa,T., Tiwari,M., Papas,K.K., McCarthy,R., Sutherland,D.E. and Hering,B.J. A new enzyme mixture to increase the yield and transplant rate of autologous and allogeneic human islet products Transplantation (2012) 93, 693-702. PubMed Europe PubMed DOI
Rozen,W.M., Edirisinghe,Y. and Crock,J. Late complications of clinical Clostridium histolyticum collagenase use in Dupuytren's disease PLoS ONE (2012) 7, e43406-e43406. PubMed Europe PubMed DOI PMC EPMC
Sides,C.R., Liyanage,R., Lay,J.O., Jr., Philominathan,S.T., Matsushita,O. and Sakon,J. Probing the 3-D structure, dynamics, and stability of bacterial collagenase collagen binding domain (apo- versus holo-) by limited proteolysis MALDI-TOF MS J Am Soc Mass Spectrom (2012) 23, 505-519. PubMed Europe PubMed DOI
Syed,F., Thomas,A.N., Singh,S., Kolluru,V., Emeigh Hart,S.G. and Bayat,A. In vitro study of novel collagenase (XIAFLEX(R)) on Dupuytren's disease fibroblasts displays unique drug related properties PLoS ONE (2012) 7, e31430-e31430. PubMed Europe PubMed DOI PMC EPMC U
Van Wart,H.E. Clostridium collagenases [ISSN:978-0-12-407744-7] (2012) 3, 607-611. DOI

2011

Collagenase clostridium histolyticum. Short-term benefit in Dupuytren's contracture, unknown long-term risks Prescrire Int (2011) 20, 285-287. PubMed Europe PubMed U
Aysan,E., Bektas,H., Ersoz,F. and Behzat,K. Role of single-dose clostridiopeptidase A collagenase in peritoneal adhesions Eur Surg Res (2011) 47, 130-134. PubMed Europe PubMed DOI U
Eckhard,U., Schonauer,E., Nuss,D. and Brandstetter,H. Structure of collagenase G reveals a chew-and-digest mechanism of bacterial collagenolysis Nat Struct Mol Biol (2011) 18, 1109-1114. PubMed Europe PubMed DOI S
Holzer,L. and Holzer,G. [Collagenase clostridum histolyticum in the management of Dupuytren's contracture] Handchir Mikrochir Plast Chir (2011) 43, 269-274. PubMed Europe PubMed DOI U
Kaplan,F.T. Collagenase clostridium histolyticum injection for the treatment of Dupuytren's contracture Drugs Today (Barc) (2011) 47, 653-667. PubMed Europe PubMed DOI U
Karagol,B.S., Okumus,N., Dursun,A., Karadag,N. and Zenciroglu,A. Early and successful enzymatic debridement via collagenase application to pinna in a preterm neonate Pediatr Dermatol (2011) 28, 600-601. PubMed Europe PubMed DOI U
Wang,Y., Paushter,D., Wang,S., Barbaro,B., Harvat,T., Danielson,K.K., Kinzer,K., Zhang,L., Qi,M. and Oberholzer,J. Highly purified versus filtered crude collagenase: comparable human islet isolation outcomes Cell Transplant (2011) 20, 1817-1825. PubMed Europe PubMed DOI
Watt,A.J. and Hentz,V.R. Collagenase clostridium histolyticum: a novel nonoperative treatment for Dupuytren's disease Int J Clin Rheumatol (2011) 6, 123-133. DOI U

2010

Gilpin,D., Coleman,S., Hall,S., Houston,A., Karrasch,J. and Jones,N. Injectable collagenase Clostridium histolyticum: a new nonsurgical treatment for Dupuytren's disease J Hand Surg Am (2010) 35, 2027-2038. PubMed Europe PubMed DOI U
Nikolic,D.M., Djordjevic,P.B., Sreckovic,V.D., Paunovic,I., Kalezic,N., Popovic,S., Nikolic,B. and Stefanovic,D. Comparative analysis of collagenase XI and liberase H1 for the isolation of human pancreatic islets Hepatogastroenterology (2010) 57, 1573-1578. PubMed Europe PubMed
Shi,L., Ermis,R., Garcia,A., Telgenhoff,D. and Aust,D. Degradation of human collagen isoforms by Clostridium collagenase and the effects of degradation products on cell migration Int Wound J (2010) 7, 87-95. PubMed Europe PubMed DOI
Singh,J., Singh,K., Shaik,B., Singh,N. and Agrawal,V.K. QSAR studies on some protease inhibitors incorporating sulphonyl-l-alanine hydroxamate moieties Oxid Commun (2010) 33, 631-651. I
Spiriti,J. and van der Vaart,A. Mechanism of the calcium-induced trans-cis isomerization of a non-prolyl peptide bond in Clostridium histolyticum collagenase Biochemistry (2010) 49, 5314-5320. PubMed Europe PubMed DOI
Thomas,A. and Bayat,A. The emerging role of Clostridium histolyticum collagenase in the treatment of Dupuytren disease Ther Clin Risk Manag (2010) 6, 557-572. PubMed Europe PubMed DOI PMC EPMC U
Watt,A.J., Curtin,C.M. and Hentz,V.R. Collagenase injection as nonsurgical treatment of Dupuytren's disease: 8-year follow-up J Hand Surg Am (2010) 35, 534-539. PubMed Europe PubMed DOI U

2009

Philominathan,S.T., Matsushita,O., Gensure,R. and Sakon,J. Ca2+-induced linker transformation leads to a compact and rigid collagen-binding domain of Clostridium histolyticum collagenase FEBS J (2009) 276, 3589-3601. PubMed Europe PubMed DOI
Philominathan,S.T., Koide,T., Hamada,K., Yasui,H., Seifert,S., Matsushita,O. and Sakon,J. Unidirectional binding of clostridial collagenase to triple helical substrates J Biol Chem (2009) 284, 10868-10876. PubMed Europe PubMed DOI PMC EPMC

2008

Eckhard,U., Nuss,D., Ducka,P., Schonauer,E. and Brandstetter,H. Crystallization and preliminary X-ray characterization of the catalytic domain of collagenase G from Clostridium histolyticum Acta Crystallograph Sect F Struct Biol Cryst Commun (2008) 64, 419-421. PubMed Europe PubMed DOI PMC EPMC
Saikumari,Y.K. and Balaram,P. An internally quenched fluorescent substrate for collagenase Biopolymers (2008) 90, 131-137. PubMed Europe PubMed DOI A

2007

Antonioli,B., Fermo,I., Cainarca,S., Marzorati,S., Nano,R., Baldissera,M., Bachi,A., Paroni,R., Ricordi,C. and Bertuzzi,F. Characterization of collagenase blend enzymes for human islet transplantation Transplantation (2007) 84, 1568-1575. PubMed Europe PubMed DOI

2005

[YEAR:27-9-2005]Barnett,M.J., Zhai,X., LeGatt,D.F., Cheng,S.B., Shapiro,A.M. and Lakey,J.R. Quantitative assessment of collagenase blends for human islet isolation Transplantation (27-9-2005) 80, 723-728. PubMed Europe PubMed DOI
Brandhorst,D., Huettler,S., Alt,A., Raemsch-Guenther,N., Kurfuerst,M., Bretzel,R.G. and Brandhorst,H. Adjustment of the ratio between collagenase class II and I improves islet isolation outcome Transplant Proc (2005) 37, 3450-3451. PubMed Europe PubMed DOI

2004

Van Wart,H.E. Clostridial collagenases [ISSN:0-12-079610-4] (2004) 2, 416-419. V

2002

[YEAR:8-3-2002]Hu,Y., Webb,E., Singh,J., Morgan,B.A., Gainor,J.A., Gordon,T.D. and Siahaan,T.J. Rapid determination of substrate specificity of Clostridium histolyticum beta-collagenase using an immobilized peptide library J Biol Chem (8-3-2002) 277, 8366-8371. PubMed Europe PubMed DOI

2001

[YEAR:21-6-2001]Clare,B.W., Scozzafava,A. and Supuran,C.T. Protease inhibitors: Synthesis of a series of bacterial collagenase inhibitors of the sulfonyl amino acyl hydroxamate type J Med Chem (21-6-2001) 44, 2253-2258. PubMed Europe PubMed DOI I
[YEAR:23-3-2001]Matsushita,O., Koide,T., Kobayashi,R., Nagata,K. and Okabe,A. Substrate recognition by the collagen-binding domain of Clostridium histolyticum class I collagenase J Biol Chem (23-3-2001) 276, 8761-8770. PubMed Europe PubMed DOI

2000

Awad,M.M., Ellemor,D.M., Bryant,A.E., Matsushita,O., Boyd,R.L., Stevens,D.L., Emmins,J.J. and Rood,J.I. Construction and virulence testing of a collagenase mutant of Clostridium perfringens Microb Pathog (2000) 28, 107-117. PubMed Europe PubMed DOI
[YEAR:6-3-2000]Scozzafava,A. and Supuran,C.T. Protease inhibitors: Synthesis of Clostridium histolyticum collagenase inhibitors incorporating sulfonyl-L-alanine hydroxamate moieties Bioorg Med Chem Lett (6-3-2000) 10, 499-502. PubMed Europe PubMed DOI I
[YEAR:4-5-2000]Scozzafava,A. and Supuran,C.T. Protease inhibitors: synthesis of potent bacterial collagenase and matrix metalloproteinase inhibitors incorporating N-4-nitrobenzylsulfonylglycine hydroxamate moieties J Med Chem (4-5-2000) 43, 1858-1865. PubMed Europe PubMed DOI I
Supuran,C.T., Briganti,F., Mincione,G. and Scozzafava,A. Protease inhibitors: synthesis of L-alanine hydroxamate sulfonylated derivatives as inhibitors of Clostridium histolyticum collagenase J Enzyme Inhib (2000) 15, 111-128. PubMed Europe PubMed I

1999

Matsushita,O., Jung,C.M., Katayama,S., Minami,J., Takahashi,Y. and Okabe,A. Gene duplication and multiplicity of collagenases in Clostridium histolyticum J Bacteriol (1999) 181, 923-933. PubMed Europe PubMed PMC EPMC

1998

[YEAR:6-2-1998]Matsushita,O., Jung,C.M., Minami,J., Katayama,S., Nishi,N. and Okabe,A. A study of the collagen-binding domain of a 116-kDa Clostridium histolyticum collagenase J Biol Chem (6-2-1998) 273, 3643-3648. PubMed Europe PubMed DOI

1997

Ohtani,K., Bando,M., Swe,T., Banu,S., Oe,M., Hayashi,H. and Shimizu,T. Collagenase gene (colA) is located in the 3'-flanking region of the perfringolysin O (pfoA) locus in Clostridium perfringens FEMS Microbiol Lett (1997) 146, 155-159. PubMed Europe PubMed DOI

1995

Wolters,G.H., Vos-Scheperkeuter,G.H., Lin,H.C. and van Schilfgaarde,R. Different roles of class I and class II Clostridium histolyticum collagenase in rat pancreatic islet isolation Diabetes (1995) 44, 227-233. PubMed Europe PubMed

1994

Matsushita,O., Yoshihara,K., Katayama,S., Minami,J. and Okabe,A. Purification and characterization of Clostridium perfringens 120-kilodalton collagenase and nucleotide sequence of the corresponding gene J Bacteriol (1994) 176, 149-156. PubMed Europe PubMed PMC EPMC

1992

French,M.F., Bhown,A. and Van Wart,H.E. Identification of Clostridium histolyticum collagenase hyperreactive sites in type I, II, and III collagens: lack of correlation with local triple helical stability J Protein Chem (1992) 11, 83-97. PubMed Europe PubMed
Hedtmann,A., Fett,H., Steffen,R. and Kramer,J. [Chemonucleolysis using chymopapain and collagenase. 3-year results of a prospective randomized study] Z Orthop Ihre Grenzgeb (1992) 130, 36-44. PubMed Europe PubMed DOI
Mallya,S.K., Mookhtiar,K.A. and Van Wart,H.E. Kinetics of hydrolysis of type I, II, and III collagens by the class I and II Clostridium histolyticum collagenases J Protein Chem (1992) 11, 99-107. PubMed Europe PubMed
Mookhtiar,K.A. and Van Wart,H.E. Clostridium histolyticum collagenases: a new look at some old enzymes Matrix Suppl (1992) 1, 116-126. PubMed Europe PubMed
Schwartz,M.A. and Van Wart,H.E. Synthetic inhibitors of bacterial and mammalian interstitial collagenases Prog Med Chem (1992) 29, 271-334. PubMed Europe PubMed DOI I

1990

Dive,V., Yiotakis,A., Nicolaou,A. and Toma,F. Inhibition of Clostridium histolyticum collagenases by phosphonamide peptide inhibitors Eur J Biochem (1990) 191, 685-693. PubMed Europe PubMed DOI I

1989

Barrett,A.J., Knight,C.G., Brown,M.A. and Tisljar,U. A continuous fluorimetric assay for clostridial collagenase and Pz-peptidase activity Biochem J (1989) 260, 259-263. PubMed Europe PubMed PMC EPMC

1988

[YEAR:20-9-1988]Angleton,E.L. and Van Wart,H.E. Preparation by direct metal exchange and kinetic study of active site metal substituted class I and class II Clostridium histolyticum collagenases Biochemistry (20-9-1988) 27, 7413-7418. PubMed Europe PubMed
[YEAR:20-9-1988]Angleton,E.L. and Van Wart,H.E. Preparation and reconstitution with divalent metal ions of class I and class II Clostridium histolyticum apocollagenases Biochemistry (20-9-1988) 27, 7406-7412. PubMed Europe PubMed
Mookhtiar,K.A., Grobelny,D., Galardy,R.E. and Van Wart,H.E. Ketone-substrate analogues of Clostridium histolyticum collagenases: tight-binding transition-state analogue inhibitors Biochemistry (1988) 27, 4299-4304. PubMed Europe PubMed I
Yiotakis,A., Hatgiyannacou,A., Dive,V. and Toma,F. New thiol inhibitors of Clostridium histolyticum collagenase: importance of the P3' position Eur J Biochem (1988) 172, 764-766. DOI I

1987

[YEAR:10-2-1987]French,M.F., Mookhtiar,K.A. and Van Wart,H.E. Limited proteolysis of type I collagen at hyperreactive sites by class I and II Clostridium histolyticum collagenases: complementary digestion patterns Biochemistry (10-2-1987) 26, 681-687. PubMed Europe PubMed

1985

[YEAR:22-10-1985]Grobelny,D. and Galardy,R.E. Aldehyde and ketone substrate analogues inhibit the collagenase of Clostridium histolyticum Biochemistry (22-10-1985) 24, 6145-6152. PubMed Europe PubMed I
[YEAR:5-11-1985]Mookhtiar,K.A., Steinbrink,D.R. and Van Wart,H.E. Mode of hydrolysis of collagen-like peptides by class I and class II Clostridium histolyticum collagenases: evidence for both endopeptidase and tripeptidylcarboxypeptidase activities Biochemistry (5-11-1985) 24, 6527-6533. PubMed Europe PubMed
[YEAR:10-3-1985]Steinbrink,D.R., Bond,M.D. and Van Wart,H.E. Substrate specificity of beta-collagenase from Clostridium histolyticum J Biol Chem (10-3-1985) 260, 2771-2776. PubMed Europe PubMed P
Van Wart,H.E. and Steinbrink,D.R. Complementary substrate specificities of class I and class II collagenases from Clostridium histolyticum Biochemistry (1985) 24, 6520-6526. PubMed Europe PubMed
Vencill,C.F., Rasnick,D., Crumley,K.V., Nishino,N. and Powers,J.C. Clostridium histolyticum collagenase: development of new thio ester, fluorogenic, and depsipeptide substrates and new inhibitors Biochemistry (1985) 24, 3149-3157. PubMed Europe PubMed I

1984

Bond,M.D. and Van Wart,H.E. Characterization of the individual collagenases from Clostridium histolyticum Biochemistry (1984) 23, 3085-3091. PubMed Europe PubMed
Bond,M.D. and Van Wart,H.E. Relationship between the individual collagenases of Clostridium histolyticum: evidence for evolution by gene duplication Biochemistry (1984) 23, 3092-3099. PubMed Europe PubMed

1982

Peterkofsky,B. [21] Bacterial collagenase Methods Enzymol (1982) 82, 453-471. DOI V

1981

[YEAR:15-5-1981]Van Wart,H.E. and Steinbrink,D.R. A continuous spectrophotometric assay for Clostridium histolyticum collagenase Anal Biochem (15-5-1981) 113, 356-365. PubMed Europe PubMed

1980

Heindl,M.C., Fermandjian,S. and Keil,B. Circular dichroism comparative studies of two bacterial collagenases and thermolysin Biochim Biophys Acta (1980) 624, 51-59. PubMed Europe PubMed

1979

Lecroisey,A. and Keil,B. Differences in the degradation of native collagen by two microbial collagenases Biochem J (1979) 179, 53-58. PubMed Europe PubMed PMC EPMC P

1976

Gilles,A.M. and Keil,B. Cleavage of beta-casein by collagenases from Achromobacter iophagus and Clostridium histolyticum FEBS Lett (1976) 65, 369-372. PubMed Europe PubMed DOI
[YEAR:19-10-1976]Lwebuga-Mukasa,J.S., Harper,E. and Taylor,P. Collagenase enzymes from Clostridium: characterization of individual enzymes Biochemistry (19-10-1976) 15, 4736-4741. PubMed Europe PubMed

1973

Hanada,K., Mizutani,T., Yamagishi,M., Tsuji,H., Misaki,T. and Sawada,J. The isolation of collagenase and its enzymological and physico-chemical properties Agric Biol Chem (1973) 37, 1771-1781.

1971

Morihara,K. and Tsuzuki,H. Comparative study of various neutral proteinases from microorganisms: specificity with oligopeptides Arch Biochem Biophys (1971) 146, 291-296. PubMed Europe PubMed

1970

[YEAR:23-10-1970]Harper,E. and Kang,A.H. Studies on the specificity of bacterial collagenase Biochem Biophys Res Commun (23-10-1970) 41, 482-487. PubMed Europe PubMed
Seifter,S. and Harper,E. The collagenases Methods Enzymol (1970) 19, 613-635.

1968

Kono,T. Purification and partial characterization of collagenolytic enzymes from Clostridium histolyticum Biochemistry (1968) 7, 1106-1114. PubMed Europe PubMed

1965

Greenberg,J., Fishman,L. and Levy,M. Positions of amino acids in mixed peptides produced from collagen by the action of collagenase Biochemistry (1965) 3, 1826-1831.
[YEAR:20-9-1965]Yoshida,E. and Noda,H. Isolation and characterization of collagenases I and II from Clostridium histolyticum Biochim Biophys Acta (20-9-1965) 105, 562-574. PubMed Europe PubMed

1964

Mandl,I., Keller,S. and Manahan,J. Multiplicity of Clostridium histolyticum collagenases Biochemistry (1964) 3, 1737-1741. PubMed Europe PubMed

1961

Conklin,D.A., Webster,M.E., Altieri,P.L., Berman,S., Lowenthal,J.P. and Gochenour,R.B. Large scale purification of proteinases from Clostridium histolyticum filtrates J Bacteriol (1961) 82, 589-594. PubMed Europe PubMed PMC EPMC

1959

Grant,N.H. and Alburn,H.E. Studies on the collagenases of Clostridium histolyticum Arch Biochem Biophys (1959) 82, 245-255. PubMed Europe PubMed

1958

Mandl,I., Zipper,H. and Ferguson,L.T. Clostridium histolyticum collagenase: its purification and properties Arch Biochem Biophys (1958) 74, 465-475. PubMed Europe PubMed

1953

Mandl,I., Maclennan,J.D. and Howes,E.L. Isolation and characterization of proteinase and collagenase from Cl. histolyticum J Clin Invest (1953) 32, 1323-1329. PubMed Europe PubMed DOI PMC EPMC

1948

Oakley,C.L., Warrack,G.H. and Warren,M.E. The kappa and lambda antigens of Clostridium welchii J Pathol Bacteriol (1948) 60, 495-503.

1945

Jennison,M.W. Bacterial collagenase J Bacteriol (1945) 50, 369-370. PubMed Europe PubMed