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Literature for peptidase M03.001: thimet oligopeptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, A Assay, K Knockout, I Inhibitor, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Climer,S.
    THOP1 Is Entailed in a Genetic Fingerprint Associated with Late-Onset Alzheimer's Disease
    Biomolecules15, PubMed  Europe PubMed DOI
    2. 2023
  2. Cavalcanti,D.M.L.P., Teofilo,T.S., Rodrigues,D., Barbosa,T.N.S. and Fontenele-Neto,J.D.
    Thimet oligopeptidase (THOP 1) distribution in cane toad (Bufo Marinus, Linnaeus, 1758) brain
    J Chem Neuroanat133, 102345-102345. PubMed  Europe PubMed DOI
  3. Neves,R.L., Marem,A., Carmona,B., Arata,J.G., Cyrillo Ramos,M.P., Justo,G.Z., Machado de Melo,F.H., Oliveira,V. and Icimoto,M.Y.
    Expression of thimet oligopeptidase (THOP) modulated by oxidative stress in human multidrug resistant (MDR) leukemia cells
    Biochimie212, 21-30. PubMed  Europe PubMed DOI
    4. 2022
  4. Marcondes,M.F.M., Santos,G.S., Bronze,F., Machado,M.F.M., Perez,K.R., Hesselink,R., de Vries,M.P., Broos,J. and Oliveira,V.
    Probing the Conformational States of Thimet Oligopeptidase in Solution
    Int J Mol Sci23, PubMed  Europe PubMed DOI
    5. 2021
  5. Al-Mohanna,T., Nejat,N., Iannetta,A.A., Hicks,L.M., Popescu,G.V. and Popescu,S.C.
    Arabidopsis thimet oligopeptidases are redox-sensitive enzymes active in the local and systemic plant immune response
    J Biol Chem100695-100695. PubMed  Europe PubMed DOI
    6. 2020
  6. Dalio,F.M., Machado,M.F.M., Marcondes,M.F., Juliano,M.A., Chagas,J.R., Cunha,R.L.O.R. and Oliveira,V.
    CPP-Ala-Ala-Tyr-PABA inhibitor analogs with improved selectivity for neurolysin or thimet oligopeptidase
    Biochem Biophys Res Commun522, 368-373. PubMed  Europe PubMed DOI  I
  7. Ferro,E.S., Gewehr,M.C.F. and Navon,A.
    Thimet Oligopeptidase Biochemical and Biological Significances: Past, Present, and Future Directions
    Biomolecules10, PubMed  Europe PubMed DOI
  8. Gewehr,M.C.F., Teixeira,A.A.S., Santos,B.A.C., Biondo,L.A., Gozzo,F.C., Cordibello,A.M., Eichler,R.A.S., Reckziegel,P., Da Silva,R.N.O., Dos Santos,N.B., Camara,N.O.S., Castoldi,A., Barreto-Chaves,M.L.M., Dale,C.S., Senger,N., Lima,J.D.C.C., Seelaender,M.C.L., Inada,A.C., Akamine,E.H., Castro,L.M., Rodrigues,A.C., Neto,J.C.R. and Ferro,E.S.
    The relevance of thimet oligopeptidase in the regulation of energy metabolism and diet-induced obesity
    Biomolecules10, PubMed  Europe PubMed DOI
    9. 2019
  9. Ichihashi,Y., Komatsu,T., Kyo,E., Matsuzaki,H., Hata,K., Watanabe,T., Ueno,T., Hanaoka,K. and Urano,Y.
    Separation-based enzymomics assay for the discovery of altered peptide-metabolizing enzymatic activities in biosamples
    Anal Chem91, 11497-11501. PubMed  Europe PubMed DOI  A
  10. Santos,N.B.D., Franco,R.D., Camarini,R., Munhoz,C.D., Eichler,R.A.S., Gewehr,M.C.F., Reckziegel,P., Llanos,R.P., Dale,C.S., Silva,V.R.O.D., Borges,V.F., Lima,B.H.F., Cunha,F.Q., Visniauskas,B., Chagas,J.R., Tufik,S., Peres,F.F., Abilio,V.C., Florio,J.C., Iwai,L.K., Rioli,V., Presoto,B.C., Guimaraes,A.O., Pesquero,J.B., Bader,M., Castro,L.M. and Ferro,E.S.
    Thimet oligopeptidase (EC 3.4.24.15) key functions suggested by knockout mice phenotype characterization
    Biomolecules9, PubMed  Europe PubMed DOI  K
  11. Visniauskas,B., Simoes,P.S.R., Dalio,F.M., Naffah-Mazzacoratti,M.D.G., Oliveira,V., Tufik,S. and Chagas,J.R.
    Sleep deprivation changes thimet oligopeptidase (THOP1) expression and activity in rat brain
    Heliyon5, e02896-e02896. PubMed  Europe PubMed DOI
    12. 2017
  12. Icimoto,M.Y., Ferreira,J.C., Yokomizo,C.H., Bim,L.V., Marem,A., Gilio,J.M., Oliveira,V. and Nantes,I.L.
    Redox modulation of thimet oligopeptidase activity by hydrogen peroxide
    FEBS Open Bio7, 1037-1050. PubMed  Europe PubMed DOI
    13. 2016
  13. Wagner,L., Bjorkqvist,M., Lundh,S.H., Wolf,R., Borgel,A., Schlenzig,D., Ludwig,H.H., Rahfeld,J.U., Leavitt,B., Demuth,H.U., Petersen,A. and von Horsten,S.
    Neuropeptide Y (NPY) in cerebrospinal fluid from patients with Huntington's Disease: increased NPY levels and differential degradation of the NPY1-30 fragment
    J Neurochem137, 820-837. PubMed  Europe PubMed DOI
  14. Woitowich,N.C., Philibert,K.D., Leitermann,R.J., Wungjiranirun,M., Urban,J.H. and Glucksman,M.J.
    EP24.15 as a potential regulator of kisspeptin within the neuroendocrine hypothalamus
    Endocrinology157, 820-830. PubMed  Europe PubMed DOI
    15. 2014
  15. Qi,L., Li,S.H., Si,L.B., Lu,M. and Tian,H.
    Expression of THOP1 and its relationship to prognosis in non-small cell lung cancer
    PLoS ONE9, e106665-e106665. PubMed  Europe PubMed DOI
  16. Simoes,P.S., Visniauskas,B., Perosa,S.R., Yacubian,E.M., Centeno,R., Canzian,M., Lopes-Cendes,I., Maurer Morelli,C.V., Carrete,H., Jr., Cavalheiro,E.A., Tufik,S., Chagas,J.R. and Naffah Mazzacoratti,M.G.
    Expression and activity of thimet oligopeptidase (TOP) are modified in the hippocampus of subjects with temporal lobe epilepsy (TLE)
    Epilepsia55, 754-762. PubMed  Europe PubMed DOI
    17. 2013
  17. Ferreira,J.C., Icimoto,M.Y., Marcondes,M.F., Oliveira,V., Nascimento,O.R. and Nantes,I.L.
    Recycling of the high valence states of heme proteins by cysteine residues of thimet-oligopeptidase
    PLoS ONE8, e79102-e79102. PubMed  Europe PubMed DOI
  18. Gamrekelashvili,J., Kapanadze,T., Han,M., Wissing,J., Ma,C., Jaensch,L., Manns,M.P., Armstrong,T., Jaffee,E., White,A.O., Citrin,D.E., Korangy,F. and Greten,T.F.
    Peptidases released by necrotic cells control CD8+ T cell cross-priming
    J Clin Invest123, 4755-4768. PubMed  Europe PubMed DOI
  19. Guinan,A.F., Rochfort,K.D., Fitzpatrick,P.A., Walsh,T.G., Pierotti,A.R., Phelan,S., Murphy,R.P. and Cummins,P.M.
    Shear stress is a positive regulator of thimet oligopeptidase (EC3.4.24.15) in vascular endothelial cells: consequences for MHC1 levels
    Cardiovasc Res99, 545-554. PubMed  Europe PubMed DOI
  20. Pereira,M.G., Souza,L.L., Becari,C., Duarte,D.A., Camacho,F.R., Oliveira,J.A., Gomes,M.D., Oliveira,E.B., Salgado,M.C., Garcia-Cairasco,N. and Costa-Neto,C.M.
    Angiotensin II-independent angiotensin-(1-7) formation in rat hippocampus: involvement of thimet oligopeptidase
    Hypertension62, 879-885. PubMed  Europe PubMed DOI
    21. 2012
  21. Barrett,A.J. and Chen,J.M.
    Thimet oligopeptidase
    [ISSN:978-0-12-407744-7]3, 504-509. DOI
  22. Malvezzi,A., Higa,P.M., Amaral,A.T., Silva,G.M., Gozzo,F.C., Ferro,E.S., Castro,L.M., de Rezende,L., Monteiro,G. and Demasi,M.
    The cysteine-rich protein thimet oligopeptidase as a model of the structural requirements for S-glutathiolation and oxidative oligomerization
    PLoS ONE7, e39408-e39408. PubMed  Europe PubMed DOI
  23. Russo,L.C., Castro,L.M., Gozzo,F.C. and Ferro,E.S.
    Inhibition of thimet oligopeptidase by siRNA alters specific intracellular peptides and potentiates isoproterenol signal transduction
    FEBS Lett586, 3287-3292. PubMed  Europe PubMed DOI  K
    24. 2011
  24. Kessler,J.H., Khan,S., Seifert,U., Le Gall,S., Chow,K.M., Paschen,A., Bres-Vloemans,S.A., de Ru,A., van Montfoort,N., Franken,K.L., Benckhuijsen,W.E., Brooks,J.M., van Hall,T., Ray,K., Mulder,A., Doxiadis,I.I., van Swieten,P.F., Overkleeft,H.S., Prat,A., Tomkinson,B., Neefjes,J., Kloetzel,P.M., Rodgers,D.W., Hersh,L.B., Drijfhout,J.W., van Veelen,P.A., Ossendorp,F. and Melief,C.J.
    Antigen processing by nardilysin and thimet oligopeptidase generates cytotoxic T cell epitopes
    Nat Immunol12, 45-53. PubMed  Europe PubMed DOI
    25. 2008
  25. Sanden,C., Enquist,J., Bengtson,S.H., Herwald,H. and Leeb-Lundberg,L.M.
    Kinin B2 receptor-mediated bradykinin internalization and metalloendopeptidase EP24.15-dependent intracellular bradykinin degradation
    J Pharmacol Exp Ther326, 24-32. PubMed  Europe PubMed DOI
    26. 2007
  26. Lim,E.J., Sampath,S., Coll-Rodriguez,J., Schmidt,J., Ray,K. and Rodgers,D.W.
    Swapping the substrate specificities of the neuropeptidases neurolysin and thimet oligopeptidase
    J Biol Chem282, 9722-9732. PubMed  Europe PubMed DOI  S
    27. 2006
  27. [YEAR:24-4-2006]Dubois,V., Nieder,M., Collot,F., Negrouk,A., Nguyen,T.T., Gangwar,S., Reitz,B., Wattiez,R., Dasnois,L. and Trouet,A.
    Thimet oligopeptidase (EC 3.4.24.15) activates CPI-0004Na, an extracellularly tumour-activated prodrug of doxorubicin
    Eur J Cancer42, 3049-3056. PubMed  Europe PubMed DOI
  28. [YEAR:8-8-2006]Kitabgi,P.
    Inactivation of neurotensin and neuromedin N by Zn metallopeptidases
    Peptides27, 2515-2522. PubMed  Europe PubMed DOI  V
    29. 2005
  29. Carreno,F.R., Goni,C.N., Castro,L.M. and Ferro,E.S.
    14-3-3 epsilon modulates the stimulated secretion of endopeptidase 24.15
    J Neurochem93, 10-25. PubMed  Europe PubMed DOI
    30. 2004
  30. Barrett,A.J. and Chen,J.M.
    Thimet oligopeptidase
    [ISSN:0-12-079610-4]2, 352-356.  V
  31. Ferro,E.S., Hyslop,S. and Camargo,A.C.
    Intracellullar peptides as putative natural regulators of protein interactions
    J Neurochem91, 769-777. PubMed  Europe PubMed DOI
  32. Jeske,N.A., Glucksman,M.J. and Roberts,J.L.
    Metalloendopeptidase EC3.4.24.15 is constitutively released from the exofacial leaflet of lipid rafts in GT1-7 cells
    J Neurochem90, 819-828. PubMed  Europe PubMed DOI
  33. [YEAR:13-8-2004]Marinova,Z., Yakovleva,T., Melzig,M.F., Hallberg,M., Nylander,I., Ray,K., Rodgers,D.W., Hauser,K.F., Ekstrom,T.J. and Bakalkin,G.
    A novel soluble protein factor with non-opioid dynorphin A-binding activity
    Biochem Biophys Res Commun321, 202-209. PubMed  Europe PubMed DOI
  34. [YEAR:7-5-2004]Ray,K., Hines,C.S., Coll-Rodriguez,J. and Rodgers,D.W.
    Crystal structure of human thimet oligopeptidase provides insight into substrate recognition, regulation, and localization
    J Biol Chem279, 20480-20489. PubMed  Europe PubMed DOI  S
  35. Rock,K.L., York,I.A. and Goldberg,A.L.
    Post-proteasomal antigen processing for major histocompatibility complex class I presentation
    Nat Immunol5, 670-677. PubMed  Europe PubMed DOI
  36. [YEAR:24-8-2004]Saric,T., Graef,C.I. and Goldberg,A.L.
    Pathway for degradation of peptides generated by proteasomes: a key role for thimet oligopeptidase and other metallopeptidases
    J Biol Chem279, 46723-46732. PubMed  Europe PubMed DOI
    37. 2003
  37. Gioli-Pereira,L., Fontenele-Neto,J.D., Borges,D.R. and Kouyoumdjian,M.
    Localization of EP24.15, a major liver kininase
    J Histochem Cytochem51, 125-127. PubMed  Europe PubMed
  38. [YEAR:1-11-2003]Jeske,N.A., Glucksman,M.J. and Roberts,J.L.
    EP24.15 is associated with lipid rafts
    J Neurosci Res74, 468-473. PubMed  Europe PubMed DOI
  39. [YEAR:1-10-2003]Kim,S.I., Pabon,A., Swanson,T.A. and Glucksman,M.J.
    Regulation of cell-surface major histocompatibility complex class I expression by the endopeptidase EC3.4.24.15 (thimet oligopeptidase)
    Biochem J375, 111-120. PubMed  Europe PubMed DOI
  40. [YEAR:1-11-2003]Kim,S.I., Grum-Tokars,V., Swanson,T.A., Cotter,E.J., Cahill,P.A., Roberts,J.L., Cummins,P.M. and Glucksman,M.J.
    Novel roles of neuropeptide processing enzymes: EC3.4.24.15 in the neurome
    J Neurosci Res74, 456-467. PubMed  Europe PubMed DOI
  41. [YEAR:15-11-2003]Morrison,L.S. and Pierotti,A.R.
    Thimet oligopeptidase expression is differentially regulated in neuroendocrine and spermatid cell lines by transcription factor binding to SRY (sex-determining region Y), CAAT and CREB (cAMP-response-element-binding protein) promoter consensus sequences
    Biochem J376, 189-197. PubMed  Europe PubMed DOI
  42. Norman,M.U., Lew,R.A., Smith,A.I. and Hickey,M.J.
    Metalloendopeptidases EC 3.4.24.15/16 regulate bradykinin activity in the cerebral microvasculature
    Am J Physiol Heart Circ Physiol284, H1942-H1948. PubMed  Europe PubMed DOI  I
  43. Norman,M.U., Reeve,S.B., Dive,V., Smith,A.I. and Lew,R.A.
    Endopeptidases 3.4.24.15 and 24.16 in endothelial cells: potential role in vasoactive peptide metabolism
    Am J Physiol Heart Circ Physiol284, H1978-H1984. PubMed  Europe PubMed DOI
  44. [YEAR:24-4-2003]Oliveira,V., Araujo,M.C., Rioli,V., de Camargo,A.C., Tersariol,I.L., Juliano,M.A., Juliano,L. and Ferro,E.S.
    A structure-based site-directed mutagenesis study on the neurolysin (EC 3.4.24.16) and thimet oligopeptidase (EC 3.4.24.15) catalysis
    FEBS Lett541, 89-92. PubMed  Europe PubMed DOI
  45. [YEAR:7-3-2003]Rioli,V., Gozzo,F.C., Heimann,A.S., Linardi,A., Krieger,J.E., Shida,C.S., Almeida,P.C., Hyslop,S., Eberlin,M.N. and Ferro,E.S.
    Novel natural peptide substrates for endopeptidase 24.15, neurolysin, and angiotensin-converting enzyme
    J Biol Chem278, 8547-8555. PubMed  Europe PubMed DOI
  46. [YEAR:1-11-2003]Shrimpton,C.N., Wolfson,A.J., Smith,A.I. and Lew,R.A.
    Regulators of the neuropeptide-degrading enzyme, EC 3.4.24.15 (thimet oligopeptidase), in cerebrospinal fluid
    J Neurosci Res74, 474-478. PubMed  Europe PubMed DOI
  47. Sigman,J.A., Sharky,M.L., Walsh,S.T., Pabon,A., Glucksman,M.J. and Wolfson,A.J.
    Involvement of surface cysteines in activity and multimer formation of thimet oligopeptidase
    Protein Eng16, 623-628. PubMed  Europe PubMed
  48. [YEAR:19-6-2003]Sigman,J.A., Edwards,S.R., Pabon,A., Glucksman,M.J. and Wolfson,A.J.
    pH dependence studies provide insight into the structure and mechanism of thimet oligopeptidase (EC 3.4.24.15)
    FEBS Lett545, 224-228. PubMed  Europe PubMed DOI
  49. York,I.A., Mo,A.X., Lemerise,K., Zeng,W., Shen,Y., Abraham,C.R., Saric,T., Goldberg,A.L. and Rock,K.L.
    The cytosolic endopeptidase, thimet oligopeptidase, destroys antigenic peptides and limits the extent of MHC class I antigen presentation
    Immunity18, 429-440. PubMed  Europe PubMed DOI
    50. 2002
  50. Goldberg,A.L., Cascio,P., Saric,T. and Rock,K.L.
    The importance of the proteasome and subsequent proteolytic steps in the generation of antigenic peptides
    Mol Immunol39, 147-164. PubMed  Europe PubMed DOI
  51. Oliveira,V., Gatti,R., Rioli,V., Ferro,E.S., Spisni,A., Camargo,A.C., Juliano,M.A. and Juliano,L.
    Temperature and salts effects on the peptidase activities of the recombinant metallooligopeptidases neurolysin and thimet oligopeptidase
    Eur J Biochem269, 4326-4334. PubMed  Europe PubMed DOI
  52. Ray,K., Hines,C.S. and Rodgers,D.W.
    Mapping sequence differences between thimet oligopeptidase and neurolysin implicates key residues in substrate recognition
    Protein Sci11, 2237-2246. PubMed  Europe PubMed DOI  S
  53. Shrimpton,C.N., Smith,A.I. and Lew,R.A.
    Soluble metalloendopeptidases and neuroendocrine signaling
    Endocr Rev23, 647-664. PubMed  Europe PubMed DOI
  54. [YEAR:3-9-2002]Steer,D., Lew,R., Perlmutter,P., Smith,A.I. and Aguilar,M.I.
    Inhibitors of metalloendopeptidase EC 3.4.24.15 and EC 3.4.24.16 stabilized against proteolysis by the incorporation of beta-amino acids
    Biochemistry41, 10819-10826. PubMed  Europe PubMed DOI  I
    55. 2001
  55. [YEAR:1-10-2001]Fontenele-Neto,J.D., Massarelli,E.E., Garrido,P.A.G., Beaudet,A. and Ferro,E.S.
    Comparative fine structural distribution of endopeptidase 24.15 (EC3.4.24.15) and 24.16 (EC3.4.24.16) in rat brain
    J Comp Neurol438, 399-410. PubMed  Europe PubMed DOI
  56. [YEAR:29-5-2001]Lew,R.A., Boulos,E., Stewart,K.M., Perlmutter,P., Harte,M.F., Bond,S., Reeve,S.B., Norman,M.U., Lew,M.J., Aguilar,M.I. and Smith,A.I.
    Substrate analogs incorporating beta-amino acids: potential application for peptidase inhibition
    FASEB J15, 1664-1666. PubMed  Europe PubMed
  57. [YEAR:10-4-2001]Oliveira,V., Campos,M., Melo,R.L., Ferro,E.S., Camargo,A.C., Juliano,M.A. and Juliano,L.
    Substrate specificity characterization of recombinant metallo oligo-peptidases thimet oligopeptidase and neurolysin
    Biochemistry40, 4417-4425. PubMed  Europe PubMed DOI
  58. Portaro,F.C., Hayashi,M.A., Silva,C.L. and de Camargo,A.C.
    Free ATP inhibits thimet oligopeptidase (EC 3.4.24.15) activity, induces autophosphorylation in vitro, and controls oligopeptide degradation in macrophage
    Eur J Biochem268, 887-894. PubMed  Europe PubMed DOI
  59. [YEAR:28-9-2001]Saric,T., Beninga,J., Graef,C.I., Akopian,T.N., Rock,K.L. and Goldberg,A.L.
    Major histocompatibility complex class I-presented antigenic peptides are degraded in cytosolic extracts primarily by thimet oligopeptidase
    J Biol Chem276, 36474-36481. PubMed  Europe PubMed DOI
    60. 2000
  60. Koike,H., Kouchi,Z., Kinouchi,T., Maeda,T., Sorimachi,H., Saido,T.C., Maruyama,K., Okuyama,A., Suzuki,K. and Ishiura,S.
    Metabolism of amyloid precursor protein in COS cells transfected with a beta-secretase candidate
    Cytotechnology33, 213-219. PubMed  Europe PubMed DOI
  61. Lew,R.A., Boulos,E., Stewart,K.M., Perlmutter,P., Harte,M.F., Bond,S., Aguilar,M.I. and Smith,A.I.
    Bradykinin analogues with beta-amino acid substitutions reveal subtle differences in substrate specificity between the endopeptidases EC 3.4.24.15 and EC 3.4.24.16
    J Pept Sci6, 440-445. PubMed  Europe PubMed DOI
  62. McCool,S. and Pierotti,A.R.
    Expression of the thimet oligopeptidase gene is regulated by positively and negatively acting elements
    DNA Cell Biol19, 729-738. PubMed  Europe PubMed DOI
  63. [YEAR:23-6-2000]Molina,H.M., Carmona,A.K., Kouyoumdjian,M. and Borges,D.R.
    Thimet oligopeptidase EC 3.4.24.15 is a major liver kininase
    Life Sci67, 509-520. PubMed  Europe PubMed DOI
  64. Okida,N., Tokumoto,M., Tokumoto,T., Nagahama,Y., Ohe,Y., Miyamoto,K. and Ishikawa,K.
    Cloning of cDNA encoding thimet oligopeptidase from Xenopus oocytes and regulation of the mRNA during oogenesis
    Zoolog Sci17, 431-436.
  65. [YEAR:15-1-2000]Shrimpton,C.N., Abbenante,G., Lew,R.A. and Smith,I.
    Development and characterization of novel potent and stable inhibitors of endopeptidase EC 3.4.24.15
    Biochem J345, 351-356. PubMed  Europe PubMed DOI  I
  66. [YEAR:24-11-2000]Tullai,J.W., Cummins,P.M., Pabon,A., Roberts,J.L., Lopingco,M.C., Shrimpton,C.N., Smith,A.I., Martignetti,J.A., Ferro,E.S. and Glucksman,M.J.
    The neuropeptide processing enzyme EC 3.4.24.15 is modulated by protein kinase A phosphorylation
    J Biol Chem275, 36514-36522. PubMed  Europe PubMed DOI
    67. 1999
  67. [YEAR:24-7-1999]Crack,P.J., Wu,T.J., Cummins,P.M., Ferro,E.S., Tullai,J.W., Glucksman,M.J. and Roberts,J.L.
    The association of metalloendopeptidase EC 3.4.24.15 at the extracellular surface of the AtT-20 cell plasma membrane
    Brain Res835, 113-124. PubMed  Europe PubMed DOI
  68. [YEAR:4-6-1999]Cummins,P.M., Pabon,A., Margulies,E.H. and Glucksman,M.J.
    Zinc coordination and substrate catalysis within the neuropeptide processing enzyme endopeptidase EC 3.4.24.15. Identification of active site histidine and glutamate residues
    J Biol Chem274, 16003-16009. PubMed  Europe PubMed DOI
  69. Ferro,E.S., Tullai,J.W., Glucksman,M.J. and Roberts,J.L.
    Secretion of metalloendopeptidase 24.15 (EC 3.4.24.15)
    DNA Cell Biol18, 781-789. PubMed  Europe PubMed DOI
  70. Garrido,P.A., Vandenbulcke,F., Ramjaun,A.R., Vincent,B., Checler,F., Ferro,E. and Beaudet,A.
    Confocal microscopy reveals thimet oligopeptidase (EC 3.4.24.15) and neurolysin (EC 3.4.24.16) in the classical secretory pathway
    DNA Cell Biol18, 323-331. PubMed  Europe PubMed DOI
  71. Koike,H., Seki,H., Kouchi,Z., Ito,M., Kinouchi,T., Tomioka,S., Sorimachi,H., Saido,T.C., Maruyama,K., Suzuki,K. and Ishiura,S.
    Thimet oligopeptidase cleaves the full-length Alzheimer amyloid precursor protein at a beta-secretase cleavage site in COS cells
    J Biochem126, 235-242. PubMed  Europe PubMed
  72. [YEAR:18-12-1999]Massarelli,E.E., Casatti,C.A., Kato,A., Camargo,A.C., Bauer,J.A., Glucksman,M.J., Roberts,J.L., Hirose,S. and Ferro,E.S.
    Differential subcellular distribution of neurolysin (EC 3.4.24.16) and thimet oligopeptidase (EC 3.4.24.15) in the rat brain
    Brain Res851, 261-265. PubMed  Europe PubMed DOI
  73. [YEAR:24-2-1999]Portaro,F.C., Gomes,M.D., Cabrera,A., Fernandes,B.L., Silva,C.L., Ferro,E.S., Juliano,L. and de Camargo,A.C.
    Thimet oligopeptidase and the stability of MHC class I epitopes in macrophage cytosol
    Biochem Biophys Res Commun255, 596-601. PubMed  Europe PubMed DOI
  74. [YEAR:24-2-1999]Silva,C.L., Portaro,F.C., Bonato,V.L., de Camargo,A.C. and Ferro,E.S.
    Thimet oligopeptidase (EC 3.4.24.15), a novel protein on the route of MHC class I antigen presentation
    Biochem Biophys Res Commun255, 591-595. PubMed  Europe PubMed DOI
  75. [YEAR:25-6-1999]Yamin,R., Malgeri,E.G., Sloane,J.A., McGraw,W.T. and Abraham,C.R.
    Metalloendopeptidase EC 3.4.24.15 is necessary for Alzheimer's amyloid-beta peptide degradation
    J Biol Chem274, 18777-18784. PubMed  Europe PubMed DOI
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