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Literature for peptidase C60.001: sortase A (Staphylococcus-type)

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, A Assay, T Target, P Specificity, I Inhibitor, E Expression, L Localization, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Helalat,S.H., Kristinsdottir,H.T., Petersen,A.D., Tellez,R.C., Boye,M.N. and Sun,Y.<br>Enzymatic assembly for CRISPR split-Cas9 system: The emergence of a Sortase-based split-Cas9 technology<br>Int J Biol Macromol (2025) 306, 141583-141583. PubMed  Europe PubMed DOI
  2. Kumar,A., Chhabra,S. and Parkesh,R.<br>Identification of prochlorperazine dimaleate as a Sortase A inhibitor from FDA libraries for MRSA infection treatment<br>RSC Adv (2025) 15, 21666-21677. PubMed  Europe PubMed DOI  PMC  EPMC  I
  3. Wang,C., Desmet,R., Snella,B., Vicogne,J., Melnyk,O. and Agouridas,V.<br>Leveraging Sortase A Electrostatics for Powerful Transpeptidation Reactions<br>Angew Chem Int Ed Engl (2025) , e202507236-e202507236. PubMed  Europe PubMed DOI
  4. Wang,C., Desmet,R., Snella,B., Melnyk,O. and Agouridas,V.<br>Improving Sortase-A-Mediated Transpeptidation Reactions by Electrostatically Assisted Capture<br>Org Lett (2025) 27, 11854-11858. PubMed  Europe PubMed DOI
  5. Yang,H.K., Muthukumar,P.K. and Chen,W.<br>Synthetic protein degradation circuits using programmable cleavage and ligation by Sortase A<br>Nat Commun (2025) 16, 8682-8682. PubMed  Europe PubMed DOI  PMC  EPMC
  6. Yang,N., Zhang,A., Zhang,Y., Chen,D. and Xie,S.<br>Oleanolic acid-taxifolin self-assembled nanoparticles for effective treatment of S. aureus infections by inhibiting its internalization and reproduction<br>Colloids Surf B Biointerfaces (2025) 257, 115199-115199. PubMed  Europe PubMed DOI
  7. Zhang,J., Kallemeijn,W.W., Hassan,S. and Tate,E.W.<br>Chemical proteomic approaches to investigate N-myristoylation<br>Methods Enzymol (2025) 718, 215-240. PubMed  Europe PubMed DOI
    8. 2024
  8. Chang,C. and Ton-That,H.<br>Detection of Cell Wall-Anchoring Machinery by Immunogold-Labeling Thin-Section Electron Microscopy<br>Methods Mol Biol (2024) 2727, 145-152. PubMed  Europe PubMed DOI
  9. Dewan,D., Basu,A., Dolai,D. and Pal,S.<br>Biological and Biophysical Methods for Evaluation of Inhibitors of Sortase A in Staphylococcus aureus: An Overview<br>Cell Biochem Funct (2024) 42, e70002-e70002. PubMed  Europe PubMed DOI  V
  10. Hall,J.W., Lima,B.P., Johnstone,K.F. and Herzberg,M.C.<br>Localization of the Remnant of a Cell Wall Sorting Signal and Its Interaction with a Sensor Kinase<br>Methods Mol Biol (2024) 2727, 153-158. PubMed  Europe PubMed DOI
  11. Hintzen,J.C.J., Abujubara,H., Tietze,D. and Tietze,A.<br>The Complete Assessment of Small Molecule and Peptidomimetic Inhibitors of Sortase A Towards Antivirulence Treatment<br>Chemistry (2024) , e202401103-e202401103. PubMed  Europe PubMed DOI  V
  12. Kodama,H.M., Lindblom,K.M., Walkenhauer,E.G., Antos,J.M. and Amacher,J.F.<br>Amino acid variability at W194 of Staphylococcus aureus sortase A alters nucleophile specificity<br>Protein Sci (2024) 33, e5212-e5212. PubMed  Europe PubMed DOI  PMC  EPMC
  13. Kumari,P., Banerjee,S.K., Murty,U.S., Ravichandiran,V. and Mohan,U.<br>Harnessing the combined effect of antivirulence agent trans-chalcone with bactericidal curcumin against sortase A enzyme to tackle Gram-positive bacterial infections<br>Folia Microbiol (Praha) (2024) 69, 639-652. PubMed  Europe PubMed DOI  I
  14. Li,X., Hou,Y., Zou,H., Wang,Y., Xu,Y., Wang,L., Wang,B., Yan,M. and Leng,X.<br>Unraveling the efficacy of verbascoside in thwarting MRSA pathogenicity by targeting sortase A<br>Appl Microbiol Biotechnol (2024) 108, 360-360. PubMed  Europe PubMed DOI  PMC  EPMC  I
  15. Liu,Y., Lu,Z., Wu,P., Liang,Z., Yu,Z., Ni,K. and Ma,L.<br>The Transpeptidase Sortase A Binds Nucleic Acids and Mediates Mammalian Cell Labeling<br>Adv Sci (Weinh) (2024) , e2305605-e2305605. PubMed  Europe PubMed DOI
  16. Ran,W., Yi,P., Jiang,L., Yu,Y., Zhong,K., Wu,Y. and Gao,H.<br>Antibiofilm mechanism of 2R,3R-dihydromyricetin by targeting sortase A and its application against Staphylococcus aureus adhesion on eggshell<br>Int J Food Microbiol (2024) 426, 110925-110925. PubMed  Europe PubMed DOI  I
  17. Scaffidi,S.J. and Yu,W.<br>Tracking Cell Wall-Anchored Proteins in Gram-Positive Bacteria<br>Methods Mol Biol (2024) 2727, 193-204. PubMed  Europe PubMed DOI
  18. Yang,B., Fu,S., Qiu,Y., Miao,J. and Zhang,J.<br>QSAR Studies on a Class of Benzofuranene Cyanide Derivatives as Potential Inhibitors Targeting Staphylococcus aureus Sortase A<br>Curr Med Chem (2024) PubMed  Europe PubMed DOI
  19. Yue,C., Yuan,Z., Xu,G., Guan,X.N., Wei,B., Yao,H., Yang,C.G. and Zhang,T.<br>Structure-Guided Design, Synthesis, and Antivirulence Assessment of Covalent Staphylococcus aureus Sortase A Inhibitors<br>J Med Chem (2024) 67, 1127-1146. PubMed  Europe PubMed DOI
  20. Zhang,Z., Wang,Y., Xu,Q., Liu,Y., Wang,K., Li,P. and Zheng,X.<br>Rosmarinic Acid Restores the Ceftiofur Antibacterial Activity against Methicillin-Resistant Staphylococcus aureus by Inhibiting Sortase A<br>J Agric Food Chem (2024) 72, 27215-27224. PubMed  Europe PubMed DOI
  21. Zhu,S., Hu,C., Wang,Y., Jin,M., Zhang,Q., Han,S., Tang,Y., Wu,D., Fu,D., Jiang,S., Song,D., Wei,L., Song,W., Zhang,C. and Zhang,W.<br>Daphnetin weakened the pathogenicity of methicillin-resistant Staphylococcus aureus by inhibiting Sortase A and alpha-hemolysin<br>Biochimie (2024) PubMed  Europe PubMed DOI  I
    22. 2023
  22. Abujubara,H., Hintzen,J.C.J., Rahimi,S., Mijakovic,I., Tietze,D. and Tietze,A.A.<br>Substrate-derived Sortase A inhibitors: targeting an essential virulence factor of Gram-positive pathogenic bacteria<br>Chem Sci (2023) 14, 6975-6985. PubMed  Europe PubMed DOI  PMC  EPMC
  23. Alharthi,S., Popat,A., Ziora,Z.M. and Moyle,P.M.<br>Sortase A Inhibitor Protein Nanoparticle Formulations Demonstrate Antibacterial Synergy When Combined with Antimicrobial Peptides<br>Molecules (2023) 28 PubMed  Europe PubMed DOI  PMC  EPMC  I
  24. Chen,F., Di,H., Wang,Y., Peng,C., Chen,R., Pan,H., Yang,C.G., Liang,H. and Lan,L.<br>The enzyme activity of sortase A is regulated by phosphorylation in Staphylococcus aureus<br>Virulence (2023) 14, 2171641-2171641. PubMed  Europe PubMed DOI  PMC  EPMC
  25. Ding,R., Shi,W.W. and Zheng,J.S.<br>Chemically Synthetic d-Sortase Enables Enzymatic Ligation of d-Peptides<br>Org Lett (2023) 25, 4857-4861. PubMed  Europe PubMed DOI
  26. Jiang,F., Cai,C., Wang,X. and Han,S.<br>A dual biomarker-targeting probe enables signal-on surface labeling of Staphylococcus aureus<br>Bioorg Med Chem Lett (2023) 93, 129428-129428. PubMed  Europe PubMed DOI
  27. Jiang,T., Yuan,D., Wang,R., Zhao,C., Xu,Y., Liu,Y., Song,W., Su,X. and Wang,B.<br>Echinacoside, a promising sortase A inhibitor, combined with vancomycin against murine models of MRSA-induced pneumonia<br>Med Microbiol Immunol (2023) 212, 421-435. PubMed  Europe PubMed DOI  I
  28. Jiang,X., Kong,X., Wang,X., Yu,Z., Guo,X., Jin,M., Chen,X., Guan,J., Wu,C., Wei,L., Zhang,C., Song,G., Jiang,T., Wang,L., Zhao,Y. and Song,W.<br>Oroxylin a glucuronide as a novel class of reversible inhibitors of Sortase a, combats MRSA-induced infections<br>J Appl Microbiol (2023) 134 PubMed  Europe PubMed DOI  I
  29. Kiehstaller,S., Hutchins,G.H., Amore,A., Gerber,A., Ibrahim,M., Hennig,S., Neubacher,S. and Grossmann,T.N.<br>Bicyclic Engineered Sortase A Performs Transpeptidation under Denaturing Conditions<br>Bioconjug Chem (2023) 34, 1114-1121. PubMed  Europe PubMed DOI  PMC  EPMC
  30. Liu,K., Tong,J., Liu,X., Liang,D., Ren,F., Jiang,N., Hao,Z., Li,S. and Wang,Q.<br>The Discovery of Novel Agents against Staphylococcus aureus by Targeting Sortase A: A Combination of Virtual Screening and Experimental Validation<br>Pharmaceuticals (Basel) (2023) 17 PubMed  Europe PubMed DOI
  31. Obeng,E.M., Steer,D.L., Fulcher,A.J. and Wagstaff,K.M.<br>Sortase A transpeptidation produces seamless, unbranched biotinylated nanobodies for multivalent and multifunctional applications<br>Nanoscale Adv (2023) 5, 2251-2260. PubMed  Europe PubMed DOI  PMC  EPMC
  32. Obeng,E.M., Steer,D.L., Fulcher,A. and Wagstaff,K.M.<br>Steric-Deficient Oligoglycine Surrogates Facilitate Multivalent and Bifunctional Nanobody Synthesis via Combined Sortase A Transpeptidation and Click Chemistry<br>Bioconjug Chem (2023) 34, 1667-1678. PubMed  Europe PubMed DOI
  33. Ragab,A., Abusaif,M.S., Gohar,N.A., Aboul-Magd,D.S., Fayed,E.A. and Ammar,Y.A.<br>Development of new spiro[1,3]dithiine-4,11'-indeno[1,2-b]quinoxaline derivatives as S. aureus Sortase A inhibitors and radiosterilization with molecular modeling simulation<br>Bioorg Chem (2023) 131, 106307-106307. PubMed  Europe PubMed DOI  I
  34. Singh,A.K. and Krezel,A.<br>Calcium-assisted sortase A cleavage of SUMOylated metallothionein constructs leads to high-yield production of human MT3<br>Microb Cell Fact (2023) 22, 125-125. PubMed  Europe PubMed DOI  PMC  EPMC
  35. Tian,L., Wang,L., Yang,F., Zhou,T. and Jiang,H.<br>Exploring the modulatory impact of isosakuranetin on Staphylococcus aureus: Inhibition of sortase A activity and alpha-haemolysin expression<br>Virulence (2023) 14, 2260675-2260675. PubMed  Europe PubMed DOI  PMC  EPMC  I
    36. 2022
  36. Apostolos,A.J., Kelly,J.J., Ongwae,G.M. and Pires,M.M.<br>Structure Activity Relationship of the Stem Peptide in Sortase A Mediated Ligation from Staphylococcus aureus<br>Chembiochem (2022) 23, e202200412-e202200412. PubMed  Europe PubMed DOI  PMC  EPMC
  37. Chen,Y., Jia,L., Zhu,G., Wang,W., Geng,M., Lu,H., Zhang,Y., Zhou,M., Zhang,F. and Cheng,X.<br>Sortase A-mediated cyclization of novel polycyclic RGD peptides for alphanubeta3 integrin targeting<br>Bioorg Med Chem Lett (2022) 73, 128888-128888. PubMed  Europe PubMed DOI
  38. Guan,X.N., Zhang,T., Yang,T., Dong,Z., Yang,S., Lan,L., Gan,J. and Yang,C.G.<br>Covalent sortase A inhibitor ML346 prevents Staphylococcus aureus infection of Galleria mellonella<br>RSC Med Chem (2022) 13, 138-149. PubMed  Europe PubMed DOI  PMC  EPMC  I
  39. Hansenova Manaskova,S., Nazmi,K., van't Hof,W., van Belkum,A., Kaman,W.E., Martin,N.I., Veerman,E.C.I. and Bikker,F.J.<br>Natural and Synthetic Sortase A Substrates Are Processed by Staphylococcus aureus via Different Pathways<br>Bioconjug Chem (2022) 33, 555-559. PubMed  Europe PubMed DOI  PMC  EPMC
  40. Lei,S., Hu,Y., Yuan,C., Sun,R., Wang,J., Zhang,Y., Zhang,Y., Lu,D., Fu,L. and Jiang,F.<br>Discovery of Sortase A covalent inhibitors with benzofuranene cyanide structures as potential antibacterial agents against Staphylococcus aureus<br>Eur J Med Chem (2022) 229, 114032-114032. PubMed  Europe PubMed DOI
  41. Song,W., Wang,L., Jin,M., Guo,X., Wang,X., Guan,J. and Zhao,Y.<br>Punicalagin, an Inhibitor of Sortase A, Is a Promising Therapeutic Drug to Combat Methicillin-Resistant Staphylococcus aureus Infections<br>Antimicrob Agents Chemother (2022) 66, e0022422-e0022422. PubMed  Europe PubMed DOI  PMC  EPMC  I
  42. Song,W., Wang,L., Zhao,Y., Lanzi,G., Wang,X., Zhang,C., Guan,J., Wang,W., Guo,X., Meng,Y., Wang,B. and Zhao,Y.<br>Hibifolin, a Natural Sortase A Inhibitor, Attenuates the Pathogenicity of Staphylococcus aureus and Enhances the Antibacterial Activity of Cefotaxime<br>Microbiol Spectr (2022) 10, e0095022-e0095022. PubMed  Europe PubMed DOI  PMC  EPMC  I
  43. Su,X., Yu,H., Wang,X., Zhang,C., Wang,H., Kong,X., Qu,Y., Luan,Y., Meng,Y., Guan,J., Song,G., Wang,L., Song,W. and Zhao,Y.<br>Cyanidin chloride protects mice from methicillin-resistant Staphylococcus aureus-induced pneumonia by targeting Sortase A<br>Virulence (2022) 13, 1434-1445. PubMed  Europe PubMed DOI  PMC  EPMC  I
  44. Tian,L., Wu,X., Yu,H., Yang,F., Sun,J., Zhou,T. and Jiang,H.<br>Isovitexin Protects Mice from Methicillin-Resistant Staphylococcus aureus-Induced Pneumonia by Targeting Sortase A<br>J Microbiol Biotechnol (2022) 32, 1284-1291. PubMed  Europe PubMed DOI  PMC  EPMC  I
  45. Wang,X., Luan,Y., Hou,J., Jiang,T., Zhao,Y., Song,W., Wang,L., Kong,X., Guan,J., Song,D., Wang,B. and Li,M.<br>The protection effect of rhodionin against methicillin-resistant Staphylococcus aureus-induced pneumonia through sortase A inhibition<br>World J Microbiol Biotechnol (2022) 39, 18-18. PubMed  Europe PubMed DOI  I
  46. Yamaguchi,S., Ikeda,R., Umeda,Y., Kosaka,T., Yamahira,S. and Okamoto,A.<br>Chemoenzymatic Labeling to Visualize Intercellular Contacts Using Lipidated SortaseA<br>Chembiochem (2022) 23, e202200474-e202200474. PubMed  Europe PubMed DOI
    47. 2021
  47. Alharthi,S., Alavi,S.E., Moyle,P.M. and Ziora,Z.M.<br>Sortase A (SrtA) inhibitors as an alternative treatment for superbug infections<br>Drug Discov Today (2021) PubMed  Europe PubMed DOI  V
  48. Barthels,F., Meyr,J., Hammerschmidt,S.J., Marciniak,T., Rader,H.J., Ziebuhr,W., Engels,B. and Schirmeister,T.<br>2-Sulfonylpyrimidines as Privileged Warheads for the Development of S. aureus Sortase A Inhibitors<br>Front Mol Biosci (2021) 8, 804970-804970. PubMed  Europe PubMed DOI  PMC  EPMC
  49. Coutinho,T.D.N.P., Barroso,F.D.D., da Silva,C.R., da Silva,A.R., Cabral,V.P.F., Sa,L.G.D.A., Candido,T.M., da Silva,L.J., Ferreira,T.L., da Silva,W.M.B., Silva,J., Marinho,E.S., Cavalcanti,B.C., Moraes,M.O., Nobre Junior,H. and Andrade Neto,J.B.<br>EFFECTS OF KETAMINE IN METHICILLIN RESISTANT S. aureus AND IN SILICO INTERACTION WITH SORTASE A<br>Can J Microbiol (2021) PubMed  Europe PubMed DOI
  50. Kumari,P., Bowmik,S., Paul,S.K., Biswas,B., Banerjee,S.K., Murty,U.S., Ravichandiran,V. and Mohan,U.<br>Sortase A: A chemoenzymatic approach for the labeling of cell surfaces<br>Biotechnol Bioeng (2021) PubMed  Europe PubMed DOI  V
  51. Nitulescu,G., Margina,D., Zanfirescu,A., Olaru,O.T. and Nitulescu,G.M.<br>Targeting Bacterial Sortases in Search of Anti-Virulence Therapies with Low Risk of Resistance Development<br>Pharmaceuticals (Basel) (2021) 14 PubMed  Europe PubMed DOI  PMC  EPMC
  52. Noth,M., Zou,Z., El-Awaad,I., Celia de Lencastre Novaes,L., Dilarri,G., Davari,M.D., Ferreira,H., Jakob,F. and Schwaneberg,U.<br>A peptide-based coating toolbox to enable click chemistry on polymers, metals, and silicon through sortagging<br>Biotechnol Bioeng (2021) PubMed  Europe PubMed DOI
  53. Piper,I.M., Struyvenberg,S.A., Valgardson,J.D., Johnson,D.A., Gao,M., Johnston,K., Svendsen,J.E., Kodama,H.M., Hvorecny,K.L., Antos,J.M. and Amacher,J.F.<br>Sequence variation in the beta7-beta8 loop of bacterial class A sortase enzymes alters substrate selectivity<br>J Biol Chem (2021) 297, 100981-100981. PubMed  Europe PubMed DOI
  54. Podracky,C.J., An,C., DeSousa,A., Dorr,B.M., Walsh,D.M. and Liu,D.R.<br>Laboratory evolution of a sortase enzyme that modifies amyloid-beta protein<br>Nat Chem Biol (2021) PubMed  Europe PubMed DOI
  55. Sapra,R., Rajora,A.K., Kumar,P., Maurya,G.P., Pant,N. and Haridas,V.<br>Chemical Biology of Sortase A Inhibition: A Gateway to Anti-infective Therapeutic Agents<br>J Med Chem (2021) 64, 13097-13130. PubMed  Europe PubMed DOI
  56. Tian,T., Zhao,J., Wang,Y., Li,B., Qiao,L., Zhang,K. and Liu,B.<br>Transpeptidation-mediated single-particle imaging assay for sensitive and specific detection of sortase with dark-field optical microscopy<br>Biosens Bioelectron (2021) 178, 113003-113003. PubMed  Europe PubMed DOI
  57. Tran,P. and Schroeder,C.I.<br>Enzymatic Ligation of Disulfide-Rich Animal Venom Peptides: Using Sortase A to Form Double-Knotted Peptides<br>Methods Mol Biol (2021) 2355, 83-92. PubMed  Europe PubMed DOI
  58. Wang,L., Jing,S., Qu,H., Wang,K., Jin,Y., Ding,Y., Yang,L., Yu,H., Shi,Y., Li,Q. and Wang,D.<br>Orientin mediates protection against MRSA-induced pneumonia by inhibiting Sortase A<br>Virulence (2021) 12, 2149-2161. PubMed  Europe PubMed DOI  PMC  EPMC  I
  59. Wang,L., Li,Q., Li,J., Jing,S., Jin,Y., Yang,L., Yu,H., Wang,D., Wang,T. and Wang,L.<br>Eriodictyol as a Potential Candidate Inhibitor of Sortase A Protects Mice From Methicillin-Resistant Staphylococcus aureus-Induced Pneumonia<br>Front Microbiol (2021) 12, 635710-635710. PubMed  Europe PubMed DOI  PMC  EPMC  I
  60. Westerlund,K., Myrhammar,A., Tano,H., Gestin,M. and Karlstrom,A.E.<br>Stability Enhancement of a Dimeric HER2-Specific Affibody Molecule through Sortase A-Catalyzed Head-to-Tail Cyclization<br>Molecules (2021) 26 PubMed  Europe PubMed DOI  PMC  EPMC
  61. Yu,W., Gillespie,K.P., Chhay,B., Svensson,A.S., Nygren,P.A., Blair,I.A., Yu,F. and Tsourkas,A.<br>Efficient Labeling of Native Human IgG by Proximity-Based Sortase-Mediated Isopeptide Ligation<br>Bioconjug Chem (2021) 32, 1058-1066. PubMed  Europe PubMed DOI
  62. Zrelovs,N., Kurbatska,V., Rudevica,Z., Leonchiks,A. and Fridmanis,D.<br>Sorting out the Superbugs: Potential of Sortase A Inhibitors among Other Antimicrobial Strategies to Tackle the Problem of Antibiotic Resistance<br>Antibiotics (Basel) (2021) 10 PubMed  Europe PubMed DOI  PMC  EPMC
    63. 2020
  63. Barthels,F., Marincola,G., Marciniak,T., Konhauser,M., Hammerschmidt,S., Bierlmeier,J., Distler,U., Wich,P.R., Tenzer,S., Schwarzer,D., Ziebuhr,W. and Schirmeister,T.<br>Asymmetric disulfanylbenzamides as irreversible and selective inhibitors of Staphylococcus aureus sortase A<br>ChemMedChem (2020) 15, 839-850. PubMed  Europe PubMed DOI  I
  64. Jaudzems,K., Kurbatska,V., Je Kabsons,A., Bobrovs,R., Rudevica,Z. and Leonchiks,A.<br>Targeting bacterial sortase A with covalent inhibitors: 27 new starting points for structure-based hit-to-lead optimization<br>ACS Infect Dis (2020) 6, 186-194. PubMed  Europe PubMed DOI  I
  65. Kumari,P., Nath,Y., Murty,U.S., Ravichandiran,V. and Mohan,U.<br>Sortase A Mediated Bioconjugation of Common Epitopes Decreases Biofilm Formation in Staphylococcus aureus<br>Front Microbiol (2020) 11, 1702-1702. PubMed  Europe PubMed DOI  PMC  EPMC
  66. Morales-Aparicio,J.C., Lara Vasquez,P., Mishra,S., Barran-Berdon,A.L., Kamat,M., Basso,K.B., Wen,Z.T. and Brady,L.J.<br>The Impacts of Sortase A and the 4'-Phosphopantetheinyl Transferase Homolog Sfp on Streptococcus mutans Extracellular Membrane Vesicle Biogenesis<br>Front Microbiol (2020) 11, 570219-570219. PubMed  Europe PubMed DOI  PMC  EPMC
  67. Park,J.S., Chung,B., Lee,W.H., Lee,J., Suh,Y., Oh,D.C., Oh,K.B. and Shin,J.<br>Sortase A-Inhibitory Coumarins from the Folk Medicinal Plant Poncirus trifoliata<br>J Nat Prod (2020) 83, 3004-3011. PubMed  Europe PubMed DOI  I
  68. Park,S.C., Chung,B., Lee,J., Cho,E., Hwang,J.Y., Oh,D.C., Shin,J. and Oh,K.B.<br>Sortase A-Inhibitory Metabolites from a Marine-Derived Fungus Aspergillus sp<br>Mar Drugs (2020) 18 PubMed  Europe PubMed DOI  I
  69. Thappeta,K.R.V., Zhao,L.N., Nge,C.E., Crasta,S., Leong,C.Y., Ng,V., Kanagasundaram,Y., Fan,H. and Ng,S.B.<br>In-Silico Identified New Natural Sortase A Inhibitors Disrupt S. aureus Biofilm Formation<br>Int J Mol Sci (2020) 21 PubMed  Europe PubMed DOI  PMC  EPMC
  70. Yang,T., Zhang,T., Guan,X.N., Dong,Z., Lan,L., Yang,S. and Yang,C.G.<br>Tideglusib and Its Analogues As Inhibitors of Staphylococcus aureus SrtA<br>J Med Chem (2020) 63, 8442-8457. PubMed  Europe PubMed DOI  I
  71. Zou,Z., Mate,D.M., Noth,M., Jakob,F. and Schwaneberg,U.<br>Enhancing robustness of sortase A by loop engineering and backbone cyclization<br>Chemistry (2020) 26, 13568-13572. PubMed  Europe PubMed DOI
  72. Zou,Z., Mate,D.M., Noth,M., Jakob,F. and Schwaneberg,U.<br>Enhancing Robustness of Sortase A by Loop Engineering and Backbone Cyclization<br>Chemistry (2020) 26, 13537-13537. PubMed  Europe PubMed DOI
    73. 2019
  73. Nitulescu,G., Mihai,D.P., Nicorescu,I.M., Olaru,O.T., Ungurianu,A., Zanfirescu,A., Nitulescu,G.M. and Margina,D.<br>Discovery of natural naphthoquinones as sortase A inhibitors and potential anti-infective solutions against Staphylococcus aureus<br>Drug Dev Res (2019) 80, 1136-1145. PubMed  Europe PubMed DOI  I
  74. Wehrli,P.M., Uzelac,I., Olsson,T., Jacso,T., Tietze,D. and Gottfries,J.<br>Discovery and development of substituted thiadiazoles as inhibitors of Staphylococcus aureus sortase A<br>Bioorg Med Chem (2019) , 115043-115043. PubMed  Europe PubMed DOI  I
  75. Wojcik,M., Eleftheriadis,N., Zwinderman,M.R.H., Domling,A.S.S., Dekker,F.J. and Boersma,Y.L.<br>Identification of potential antivirulence agents by substitution-oriented screening for inhibitors of Streptococcus pyogenes sortase A<br>Eur J Med Chem (2019) 161, 93-100. PubMed  Europe PubMed DOI  I
  76. Wojcik,M., Vazquez Torres,S., Quax,W.J. and Boersma,Y.L.<br>Sortase mutants with improved protein thermostability and enzymatic activity obtained by consensus design<br>Protein Eng Des Sel (2019) 32, 555-564. PubMed  Europe PubMed DOI
  77. Younis,S., Taj,S. and Rashid,S.<br>Structural studies of Staphylococcus aureus sortase inhibiton via Conus venom peptides<br>Arch Biochem Biophys (2019) 671, 87-102. PubMed  Europe PubMed DOI
    78. 2018
  78. Harmand,T.J., Bousbaine,D., Chan,A., Zhang,X., Liu,D.R., Tam,J.P. and Ploegh,H.L.<br>One-pot dual labeling of IgG 1 and preparation of C-to-C fusion proteins through a combination of sortase A and butelase 1<br>Bioconjug Chem (2018) 29, 3245-3249. PubMed  Europe PubMed DOI
  79. Hou,X., Wang,M., Wen,Y., Ni,T., Guan,X., Lan,L., Zhang,N., Zhang,A. and Yang,C.G.<br>Quinone skeleton as a new class of irreversible inhibitors against Staphylococcus aureus sortase A<br>Bioorg Med Chem Lett (2018) 28, 1864-1869. PubMed  Europe PubMed DOI  I
  80. Li,Y., Yang,Y. and Zhang,C.Y.<br>Visualization and quantification of sortase activity at the single-molecule level via transpeptidation-directed intramolecular Forster resonance energy transfer<br>Anal Chem (2018) 90, 13007-13012. PubMed  Europe PubMed DOI  A  L
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