Literature for peptidase C54.001: ATG4 peptidase

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

(Topics flags: A Assay, K Knockout, P Specificity, I Inhibitor, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2024
  1. Li,H., Song,J.Z., He,C.W., Xie,M.X., Zhang,Z.T., Zhou,Y., Li,X.J., Cui,L., Zhu,J., Gong,Q. and Xie,Z.
    Temporal dissection of the roles of Atg4 and ESCRT in autophagosome formation in yeast
    Cell Death Differ PubMed  Europe PubMed DOI
  2. 2022
  3. Hiura,F., Kawabata,Y., Aoki,T., Mizokami,A. and Jimi,E.
    Inhibition of the ATG4-LC3 pathway suppressed osteoclast maturation
    Biochem Biophys Res Commun632, 40-47. PubMed  Europe PubMed DOI
  4. 2021
  5. Ketteler,R. and Tooze,S.A.
    ATG4: More Than a Protease?
    Trends Cell Biol31, 515-516. PubMed  Europe PubMed DOI
  6. Viret,C. and Faure,M.
    Lipidation status of single membrane-associated ATG8 proteins
    Trends Biochem Sci PubMed  Europe PubMed DOI
  7. Xia,F., Liu,P. and Li,M.
    The regulatory factors and pathological roles of autophagy-related protein 4 in diverse diseases: Recent research advances
    Med Res Rev41, 1644-1675. PubMed  Europe PubMed DOI
  8. 2020
  9. Roberto,T.N., Lima,R.F., Pascon,R.C., Idnurm,A. and Vallim,M.A.
    Biological functions of the autophagy-related proteins Atg4 and Atg8 in Cryptococcus neoformans
    PLoS ONE15, e0230981-e0230981. PubMed  Europe PubMed DOI
  10. Zhou,D., Xie,M., Bai,N., Yang,L., Zhang,K.Q. and Yang,J.
    The Autophagy-Related Gene Aolatg4 Regulates Hyphal Growth, Sporulation, Autophagosome Formation, and Pathogenicity in Arthrobotrys oligospora
    Front Microbiol11, 592524-592524. PubMed  Europe PubMed DOI
  11. 2019
  12. Herhaus,L., Bhaskara,R.M., Lystad,A.H., Gestal-Mato,U., Covarrubias-Pinto,A., Bonn,F., Simonsen,A., Hummer,G. and Dikic,I.
    TBK1-mediated phosphorylation of LC3C and GABARAP-L2 controls autophagosome shedding by ATG4 protease
    EMBO Repe48317-e48317. PubMed  Europe PubMed DOI
  13. Liu,N., Ren,W., Li,F., Chen,C. and Ma,Z.
    Involvement of the cysteine protease BcAtg4 in development and virulence of Botrytis cinerea
    Curr Genet65, 293-300. PubMed  Europe PubMed DOI
  14. 2018
  15. Liu,P.F., Tsai,K.L., Hsu,C.J., Tsai,W.L., Cheng,J.S., Chang,H.W., Shiau,C.W., Goan,Y.G., Tseng,H.H., Wu,C.H., Reed,J.C., Yang,L.W. and Shu,C.W.
    Drug repurposing screening identifies tioconazole as an ATG4 inhibitor that suppresses autophagy and sensitizes cancer cells to chemotherapy
    Theranostics8, 830-845. PubMed  Europe PubMed DOI  I
  16. 2017
  17. Abreu,S., Kriegenburg,F., Gomez-Sanchez,R., Mari,M., Sanchez-Wandelmer,J., Skytte Rasmussen,M., Soares Guimaraes,R., Zens,B., Schuschnig,M., Hardenberg,R., Peter,M., Johansen,T., Kraft,C., Martens,S. and Reggiori,F.
    Conserved Atg8 recognition sites mediate Atg4 association with autophagosomal membranes and Atg8 deconjugation
    EMBO Rep18, 765-780. PubMed  Europe PubMed DOI
  18. Li,M., Fu,Y., Yang,Z. and Yin,X.-M.
    Measurement of the activity of the Atg4 cysteine proteases
    Methods Enzymol587, 207-225. DOI  A
  19. Lopez-Otin,C. and Marino,G.
    Tagged ATG8-coding constructs for the in vitro and in vivo assessment of ATG4 activity
    Methods Enzymol587, 189-205. PubMed  Europe PubMed DOI  A
  20. Maruyama,T. and Noda,N.N.
    Autophagy-regulating protease Atg4: structure, function, regulation and inhibition
    J Antibiot (Tokyo)71, 72-78. PubMed  Europe PubMed DOI
  21. Morishita,H., Kaizuka,T., Hama,Y. and Mizushima,N.
    A new probe to measure autophagic flux in vitro and in vivo
    Autophagy13, 757-758. PubMed  Europe PubMed DOI
  22. Sanchez-Wandelmer,J., Kriegenburg,F., Rohringer,S., Schuschnig,M., Gomez-Sanchez,R., Zens,B., Abreu,S., Hardenberg,R., Hollenstein,D., Gao,J., Ungermann,C., Martens,S., Kraft,C. and Reggiori,F.
    Atg4 proteolytic activity can be inhibited by Atg1 phosphorylation
    Nat Commun8, 295-295. PubMed  Europe PubMed DOI
  23. 2016
  24. Seo,E., Woo,J., Park,E., Bertolani,S.J., Siegel,J.B., Choi,D. and Dinesh-Kumar,S.P.
    Comparative analyses of ubiquitin-like ATG8 and cysteine protease ATG4 autophagy genes in the plant lineage and cross-kingdom processing of ATG8 by ATG4
    Autophagy12, 2054-2068. PubMed  Europe PubMed DOI  P
  25. 2014
  26. Frey,S. and Gorlich,D.
    Purification of protein complexes of defined subunit stoichiometry using a set of orthogonal, tag-cleaving proteases
    J Chromatogr A1337, 106-115. PubMed  Europe PubMed DOI  P
  27. Frey,S. and Gorlich,D.
    A new set of highly efficient, tag-cleaving proteases for purifying recombinant proteins
    J Chromatogr A1337, 95-105. PubMed  Europe PubMed DOI  P
  28. Perez-Perez,M.E., Zaffagnini,M., Marchand,C.H., Crespo,J.L. and Lemaire,S.D.
    The yeast autophagy protease Atg4 is regulated by thioredoxin
    Autophagy10, 1953-1964. PubMed  Europe PubMed DOI
  29. 2013
  30. Lopez-Alonso,I., Aguirre,A., Gonzalez-Lopez,A., Fernandez,A.F., Amado-Rodriguez,L., Astudillo,A., Batalla-Solis,E. and Albaiceta,G.M.
    Impairment of autophagy decreases ventilator-induced lung injury by blockade of the NF-kappaB pathway
    Am J Physiol Lung Cell Mol Physiol304, L844-L852. PubMed  Europe PubMed DOI  K
  31. Nakatogawa,H.
    Two ubiquitin-like conjugation systems that mediate membrane formation during autophagy
    Essays Biochem55, 39-50. PubMed  Europe PubMed DOI
  32. 2012
  33. Li,M., Chen,X., Ye,Q.Z., Vogt,A. and Yin,X.M.
    A high-throughput FRET-based assay for determination of Atg4 activity
    Autophagy8, 401-412. PubMed  Europe PubMed DOI  A
  34. Li,Y., Luo,Q., Yuan,L., Miao,C., Mu,X., Xiao,W., Li,J., Sun,T. and Ma,E.
    JNK-dependent Atg4 upregulation mediates asperphenamate derivative BBP-induced autophagy in MCF-7 cells
    Toxicol Appl Pharmacol263, 21-31. PubMed  Europe PubMed DOI
  35. Nakatogawa,H. and Ohsumi,Y.
    ATG4 proteases in autophagy
    [ISSN:978-0-12-407743-0]3, 2138-2142. DOI
  36. Nakatogawa,H., Ishii,J., Asai,E. and Ohsumi,Y.
    Atg4 recycles inappropriately lipidated Atg8 to promote autophagosome biogenesis
    Autophagy8, 177-186. PubMed  Europe PubMed DOI
  37. 2011
  38. Choi,K.M., Nam,H.Y., Na,J.H., Kim,S.W., Kim,S.Y., Kim,K., Kwon,I.C. and Ahn,H.J.
    A monitoring method for Atg4 activation in living cells using peptide-conjugated polymeric nanoparticles
    Autophagy7, 1052-1062. PubMed  Europe PubMed DOI
  39. 2010
  40. Filomeni,G., Desideri,E., Cardaci,S., Rotilio,G. and Ciriolo,M.R.
    Under the ROS thiol network is the principal suspect for autophagy commitment
    Autophagy6, 999-1005. PubMed  Europe PubMed DOI
  41. Liu,T.B., Liu,X.H., Lu,J.P., Zhang,L., Min,H. and Lin,F.C.
    The cysteine protease MoAtg4 interacts with MoAtg8 and is required for differentiation and pathogenesis in Magnaporthe oryzae
    Autophagy6, 74-85. PubMed  Europe PubMed DOI
  42. 2007
  43. Scherz-Shouval,R., Shvets,E., Fass,E., Shorer,H., Gil,L. and Elazar,Z.
    Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4
    EMBO J26, 1749-1760. PubMed  Europe PubMed DOI
  44. 2004
  45. Kirisako,T. and Ohsumi,Y.
    The yeast Apg4/Aut2 protease in autophagy
    [ISSN:0-12-079610-4]2, 1243-1245.  V
  46. 2003
  47. Klionsky,D.J., Cregg,J.M., Dunn,W.A., Jr., Emr,S.D., Sakai,Y., Sandoval,I.V., Sibirny,A., Subramani,S., Thumm,M., Veenhuis,M. and Ohsumi,Y.
    A unified nomenclature for yeast autophagy-related genes
    Dev Cell5, 539-545. PubMed  Europe PubMed DOI
  48. 2000
  49. Kirisako,T., Ichimura,Y., Okada,H., Kabeya,Y., Mizushima,N., Yoshimori,T., Ohsumi,M., Takao,T., Noda,T. and Ohsumi,Y.
    The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway
    J Cell Biol151, 263-276. PubMed  Europe PubMed DOI