Literature for peptidase C46.002: Sonic hedgehog protein

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: S Structure, M Mutation, E Expression. To select only the references relevant to a single topic, click the link above. See explanation.)

    2018
  1. Roelink,H.
    Sonic Hedgehog is a member of the Hh/DD-peptidase family that spans the eukaryotic and bacterial domains of life
    J Dev Biol6, 12-12. PubMed  Europe PubMed DOI  M
  2. Xin,X., Ding,Y., Yang,Y., Fu,X., Zhou,J., McKee,C.M., Muschel,R.J., Gale,R.P., Apperley,J.F. and Xu,D.
    Protease nexin-1 prevents growth of human B cell lymphoma via inhibition of sonic hedgehog signaling
    Blood Cancer J8, 24-24. PubMed  Europe PubMed DOI
  3. 2014
  4. Rebollido-Rios,R., Bandari,S., Wilms,C., Jakuschev,S., Vortkamp,A., Grobe,K. and Hoffmann,D.
    Signaling domain of sonic hedgehog as cannibalistic calcium-regulated zinc-peptidase
    PLoS Comput Biol10, e1003707-e1003707. PubMed  Europe PubMed DOI
  5. 2007
  6. Zavros,Y., Waghray,M., Tessier,A., Bai,L., Todisco,A., Gumucio,L., Samuelson,L.C., Dlugosz,A. and Merchant,J.L.
    Reduced pepsin A processing of sonic hedgehog in parietal cells precedes gastric atrophy and transformation
    J Biol Chem282, 33265-33274. PubMed  Europe PubMed DOI
  7. 2003
  8. Shapiro,R.I., Wen,D., Levesque,M., Hronowski,X., Gill,A., Garber,E.A., Galdes,A., Strauch,K.L. and Taylor,F.R.
    Expression of Sonic hedgehog-Fc fusion protein in Pichia pastoris. Identification and control of post-translational, chemical, and proteolytic modifications
    Protein Expr Purif29, 272-283. PubMed  Europe PubMed  E
  9. 2001
  10. Bingham,S., Nasevicius,A., Ekker,S.C. and Chandrasekhar,A.
    Sonic hedgehog and tiggy-winkle hedgehog cooperatively induce zebrafish branchiomotor neurons
    Genesis30, 170-174. PubMed  Europe PubMed DOI
  11. Etheridge,L.A., Wu,T., Liang,J.O., Ekker,S.C. and Halpern,M.E.
    Floor plate develops upon depletion of tiggy-winkle and sonic hedgehog
    Genesis30, 164-169. PubMed  Europe PubMed DOI
  12. Pathi,S., Pagan-Westphal,S., Baker,D.P., Garber,E.A., Rayhorn,P., Bumcrot,D., Tabin,C.J., Blake Pepinsky,R. and Williams,K.P.
    Comparative biological responses to human Sonic, Indian, and Desert hedgehog
    Mech Dev106, 107-117. PubMed  Europe PubMed DOI
  13. 2000
  14. Pons,S. and Marti,E.
    Sonic hedgehog synergizes with the extracellular matrix protein vitronectin to induce spinal motor neuron differentiation
    Development127, 333-342. PubMed  Europe PubMed
  15. [YEAR:15-4-2000]Stenkamp,D.L., Frey,R.A., Prabhudesai,S.N. and Raymond,P.A.
    Function for Hedgehog genes in zebrafish retinal development
    Dev Biol220, 238-252. PubMed  Europe PubMed DOI
  16. 1999
  17. [YEAR:9-11-1999]Day,E.S., Wen,D., Garber,E.A., Hong,J., Avedissian,L.S., Rayhorn,P., Shen,W., Zeng,C., Bailey,V.R., Reilly,J.O., Roden,J.A., Moore,C.B., Williams,K.P., Galdes,A., Whitty,A. and Baker,D.P.
    Zinc-dependent structural stability of human Sonic hedgehog
    Biochemistry38, 14868-14880. PubMed  Europe PubMed DOI
  18. [YEAR:28-9-1999]Fuse,N., Maiti,T., Wang,B., Porter,J.A., Hall,T.M., Leahy,D.J. and Beachy,P.A.
    Sonic hedgehog protein signals not as a hydrolytic enzyme but as an apparent ligand for Patched
    Proc Natl Acad Sci U S A96, 10992-10999. PubMed  Europe PubMed DOI
  19. 1997
  20. Weed,M., Mundlos,S. and Olsen,B.R.
    The role of sonic hedgehog in vertebrate development
    Matrix Biol16, 53-58. PubMed  Europe PubMed DOI
  21. 1996
  22. Kumar,S., Balczarek,K.A. and Lai,Z.C.
    Evolution of the hedgehog gene family
    Genetics142, 965-972. PubMed  Europe PubMed
  23. Marigo,V., Davey,R.A., Zuo,Y., Cunningham,J.M. and Tabin,C.J.
    Biochemical evidence that Patched is the Hedgehog receptor
    Nature384, 176-179. PubMed  Europe PubMed DOI
  24. 1995
  25. Bumcrot,D.A., Takada,R. and McMahon,A.P.
    Proteolytic processing yields two secreted forms of sonic hedgehog
    Mol Cell Biol15, 2294-2303. PubMed  Europe PubMed
  26. Hall,T.M., Porter,J.A., Beachy,P.A. and Leahy,D.J.
    A potential catalytic site revealed by the 1.7-A crystal structure of the amino-terminal signalling domain of Sonic hedgehog
    Nature378, 212-216. PubMed  Europe PubMed DOI  S
  27. Lopez-Martinez,A., Chang,D.T., Chiang,C., Porter,J.A., Ros,M.A., Simandl,B.K., Beachy,P.A. and Fallon,J.F.
    Limb-patterning activity and restricted posterior localization of the amino-terminal product of Sonic hedgehog cleavage
    Curr Biol5, 791-796. PubMed  Europe PubMed
  28. Marigo,V., Roberts,D.J., Lee,S.M.K., Tsukurov,O., Levi,T., Gastier,J.M., Epstein,D.J., Gibert,D.J., Copeland,N.G., Seidman,C.E., Jenkins,N.A., Seidman,J.G., McMahon,A.P. and Tabin,C.
    Cloning, expression, and chromosomal location of SHH and IHH: two human homologues of the Drosophila segment polarity gene hedgehog
    Genomics28, 44-51. PubMed  Europe PubMed DOI