Literature for family C30 unassigned peptidases

(Topics flags: S Structure, P Specificity, I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)

2025
1. Li,C., Shi,Y., Xie,C., Duan,K., Ding,T., Xu,X., Fang,L., Zhou,Y. and Xiao,S.
   GSDMD and GSDME exhibit distinct roles in enteric coronavirus PDCoV-induced pyroptosis and inflammatory responses
   J Virol (2025) , e0187624-e0187624. PubMed  Europe PubMed DOI
2. Martianez-Vendrell,X., van Kasteren,P.B., Myeni,S.K. and Kikkert,M.
   HCoV-229E Mpro Suppresses RLR-Mediated Innate Immune Signalling Through Cleavage of NEMO and Through Other Mechanisms
   Int J Mol Sci (2025) 26 PubMed  Europe PubMed DOI  PMC  EPMC
2024
3. Huang,H., Lei,X., Zhao,C., Qin,Y., Li,Y., Zhang,X., Li,C., Lan,T., Zhao,B., Sun,W., Lu,H. and Jin,N.
   Porcine deltacoronavirus nsp5 antagonizes type I interferon signaling by cleaving IFIT3
   J Virol (2024) 98, e0168223-e0168223. PubMed  Europe PubMed DOI  PMC  EPMC
4. Li,Z., Xiao,W., Yang,Z., Guo,J., Zhou,J., Xiao,S., Fang,P. and Fang,L.
   Cleavage of HDAC6 to dampen its antiviral activity by nsp5 is a common strategy of swine enteric coronaviruses
   J Virol (2024) 98, e0181423-e0181423. PubMed  Europe PubMed DOI  PMC  EPMC
2023
5. Zvornicanin,S.N., Shaqra,A.M., Huang,Q.J., Ornelas,E., Moghe,M., Knapp,M., Moquin,S., Dovala,D., Schiffer,C.A. and Kurt Yilmaz,N.
   Crystal Structures of Inhibitor-Bound Main Protease from Delta- and Gamma-Coronaviruses
   Viruses (2023) 15 PubMed  Europe PubMed DOI  PMC  EPMC  I
2022
6. Wang,F., Chen,C., Wang,Z., Han,X., Shi,P., Zhou,K., Liu,X., Xiao,Y., Cai,Y., Huang,J., Zhang,L. and Yang,H.
   The Structure of the Porcine Deltacoronavirus Main Protease Reveals a Conserved Target for the Design of Antivirals
   Viruses (2022) 14 PubMed  Europe PubMed DOI  PMC  EPMC
2020
7. Zhu,X., Chen,J., Tian,L., Zhou,Y., Xu,S., Long,S., Wang,D., Fang,L. and Xiao,S.
   Porcine deltacoronavirus nsp5 cleaves DCP1A to decrease its antiviral ability
   J Virol (2020) 94, e02162-19-e02162-19. PubMed  Europe PubMed DOI
2017
8. Zhu,X., Wang,D., Zhou,J., Pan,T., Chen,J., Yang,Y., Lv,M., Ye,X., Peng,G., Fang,L. and Xiao,S.
   Porcine deltacoronavirus Nsp5 antagonizes type I interferon signaling by cleaving STAT2
   J Virol (2017) 91, e00003-17-e00003-17. PubMed  Europe PubMed DOI
2015
9. St John,S.E., Tomar,S., Stauffer,S.R. and Mesecar,A.D.
   Targeting zoonotic viruses: structure-based inhibition of the 3C-like protease from bat coronavirus HKU4-the likely reservoir host to the human coronavirus that causes Middle East Respiratory Syndrome (MERS)
   Bioorg Med Chem (2015) 23, 6036-6048. PubMed  Europe PubMed DOI  S  I
2013
10. Ren,Z., Yan,L., Zhang,N., Guo,Y., Yang,C., Lou,Z. and Rao,Z.
    The newly emerged SARS-like coronavirus HCoV-EMC also has an "Achilles' heel": current effective inhibitor targeting a 3C-like protease
    Protein Cell (2013) 4, 248-250. PubMed  Europe PubMed DOI  S  I
2011
11. Chuck,C.P., Chow,H.F., Wan,D.C. and Wong,K.B.
    Profiling of substrate specificities of 3C-like proteases from group 1, 2a, 2b, and 3 coronaviruses
    PLoS ONE (2011) 6, e27228-e27228. PubMed  Europe PubMed DOI  PMC  EPMC  P
2005
12. Woo,P.C., Huang,Y., Lau,S.K., Tsoi,H.W. and Yuen,K.Y.
    In silico analysis of ORF1ab in coronavirus HKU1 genome reveals a unique putative cleavage site of coronavirus HKU1 3C-like protease
    Microbiol Immunol (2005) 49, 899-908. PubMed  Europe PubMed