Literature for peptidase C14.044: metacaspase TbMCA2

(Topics flags: S Structure, P Specificity, I Inhibitor, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

2026
1. Duarte,A.C.M., de Oliveira,V.H., Costa,J.P.M.S., Trujilho,M.N.R., de Souza Judice,W.A. and Machado,M.F.M.
   Calcium dependence and biochemical characterization of metacaspase-3 from Trypanosoma cruzi
   Biochim Biophys Acta Proteins Proteom (2026) 1874, 141122-141122. PubMed  Europe PubMed DOI
2024
2. Araujo,L.H., Bueno Chagas,T.A., Reis,T., de Morais Borba,J.R.B., Trujilho,M.N.R., Dalzoto,L.A.M., Marcondes,M.F., Juliano,M.A., Judice,W.A.S., Veloso,M.P. and Machado,M.F.M.
   Oximic compounds as potential inhibitors of metacaspase-2 (TbMCA2) of Trypanosoma brucei
   Biochem Biophys Res Commun (2024) 735, 150657-150657. PubMed  Europe PubMed DOI  I
2020
3. Eyssen,L.E. and Coetzer,T.H.
   Validation of ligands targeting metacaspase-2 (MCA2) from Trypanosoma brucei brucei and their application to MCA5 from T. congolense as possible trypanocides
   J Mol Graph Model (2020) 97, 107579-107579. PubMed  Europe PubMed DOI
2017
4. De Castro,E., Reus,T.L., de Aguiar,A.M., Avila,A.R. and de Arruda Campos Brasil de Souza,T.
   Procaspase-activating compound-1 induces apoptosis in Trypanosoma cruzi
   Apoptosis (2017) 22, 1564-1577. PubMed  Europe PubMed DOI
5. Gilio,J.M., Marcondes,M.F., Ferrari,D., Juliano,M.A., Juliano,L., Oliveira,V. and Machado,M.F.
   Processing of metacaspase 2 from Trypanosoma brucei (TbMCA2) broadens its substrate specificity
   Biochim Biophys Acta (2017) 1865, 388-394. PubMed  Europe PubMed DOI
2013
6. Machado,M.F., Marcondes,M.F., Juliano,M.A., McLuskey,K., Mottram,J.C., Moss,C.X., Juliano,L. and Oliveira,V.
   Substrate specificity and the effect of calcium on Trypanosoma brucei metacaspase 2
   FEBS J (2013) 280, 2608-2621. PubMed  Europe PubMed DOI  P
2012
7. Laverriere,M., Cazzulo,J.J. and Alvarez,V.E.
   Antagonic activities of Trypanosoma cruzi metacaspases affect the balance between cell proliferation, death and differentiation
   Cell Death Differ (2012) 19, 1358-1369. PubMed  Europe PubMed DOI
8. McLuskey,K., Rudolf,J., Proto,W.R., Isaacs,N.W., Coombs,G.H., Moss,C.X. and Mottram,J.C.
   Crystal structure of a Trypanosoma brucei metacaspase
   Proc Natl Acad Sci U S A (2012) 109, 7469-7474. PubMed  Europe PubMed DOI  S
2011
9. Meslin,B., Zalila,H., Fasel,N., Picot,S. and Bienvenu,A.L.
   Are protozoan metacaspases potential parasite killers?
   Parasit Vectors (2011) 4, 26-26. PubMed  Europe PubMed DOI  PMC  EPMC
10. Tsiatsiani,L., Van Breusegem,F., Gallois,P., Zavialov,A., Lam,E. and Bozhkov,P.V.
    Metacaspases
    Cell Death Differ (2011) 18, 1279-1288. PubMed  Europe PubMed DOI  V
2010
11. Berg,M., Van der Veken,P., Joossens,J., Muthusamy,V., Breugelmans,M., Moss,C.X., Rudolf,J., Cos,P., Coombs,G.H., Maes,L., Haemers,A., Mottram,J.C. and Augustyns,K.
    Design and evaluation of Trypanosoma brucei metacaspase inhibitors
    Bioorg Med Chem Lett (2010) 20, 2001-2006. PubMed  Europe PubMed DOI  I
2007
12. Moss,C.X., Westrop,G.D., Juliano,L., Coombs,G.H. and Mottram,J.C.
    Metacaspase 2 of Trypanosoma brucei is a calcium-dependent cysteine peptidase active without processing
    FEBS Lett (2007) 581, 5635-5639. PubMed  Europe PubMed DOI
2006
13. [YEAR:15-3-2006]Helms,M.J., Ambit,A., Appleton,P., Tetley,L., Coombs,G.H. and Mottram,J.C.
    Bloodstream form Trypanosoma brucei depend upon multiple metacaspases associated with RAB11-positive endosomes
    J Cell Sci (15-3-2006) 119, 1105-1117. PubMed  Europe PubMed DOI
14. [YEAR:23-9-2006]Kosec,G., Alvarez,V.E., Aguero,F., Sanchez,D., Dolinar,M., Turk,B., Turk,V. and Cazzulo,J.J.
    Metacaspases of Trypanosoma cruzi: possible candidates for programmed cell death mediators
    Mol Biochem Parasitol (23-9-2006) 145, 18-28. PubMed  Europe PubMed DOI
15. Kosec,G., Alvarez,V. and Cazzulo,J.J.
    Cysteine proteinases of Trypanosoma cruzi: from digestive enzymes to programmed cell death mediators
    Biocell (2006) 30, 479-490. PubMed  Europe PubMed