$VAR1 = undef;

Summary for peptidase C14.044: metacaspase TbMCA2

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

 

Names
MEROPS Namemetacaspase TbMCA2
Other namesmetacaspase-2, TbMCA3 (Trypanosoma brucei)
Domain architecture
MEROPS Classification
Classification Clan CD >> Subclan (none) >> Family C14 >> Subfamily B >> C14.044
Holotypemetacaspase TbMCA2 (Trypanosoma brucei) (peptidase unit: 45-344), MERNUM MER0039476
History Identifier created: MEROPS 8.0 (8 January 2008)
Activity
Catalytic typeCysteine
NC-IUBMBNot yet included in IUBMB recommendations.
Other databases PANTHERhttp://www.pantherdb.org/panther/familyList.do?searchType=basic&fieldName=all&listType=6&fieldValue=PTHR31773:SF18
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/Kdg/-/RScissile bondS/S/A/Q (based on 11 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 2 1 0 1 0 0 1
Pro 0 0 0 0 0 0 0 0
Ala 1 0 2 0 0 0 6 0
Val 0 0 1 0 0 0 0 0
Leu 0 0 1 0 0 1 0 0
Ile 0 0 0 0 0 0 0 0
Met 0 0 0 0 0 0 0 0
Phe 0 0 2 0 0 0 0 0
Tyr 0 0 1 0 0 0 0 0
Trp 0 0 0 0 0 0 0 0
Ser 0 0 0 0 5 5 0 0
Thr 0 0 0 0 0 1 0 1
Cys 0 0 0 0 0 0 0 0
Asn 0 0 0 0 1 0 0 0
Gln 0 0 0 0 0 0 0 5
Asp 0 2 0 0 0 0 0 0
Glu 0 0 0 0 0 0 0 0
Lys 0 5 0 2 0 0 0 0
Arg 1 0 3 9 0 0 0 0
His 0 0 0 0 0 0 1 0