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Literature for peptidase C14.035: metacaspase Yca1 (Saccharomyces cerevisiae-type)

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, K Knockout, P Specificity, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2024
  1. Bienvenu,A.L., Ballut,L. and Picot,S.<br>Specifically Targeting Metacaspases of Candida: A New Therapeutic Opportunity<br>J Fungi (Basel) (2024) 10 PubMed  Europe PubMed DOI  PMC  EPMC  V
    2. 2023
  2. Dalzoto,L.A.M., Trujilho,M.N.R., Santos,T.D.R., Costa,J.P.M.S., Duarte,A.C.M., Judice,W.A.S., Marcondes,M.F. and Machado,M.F.M.<br>Metacaspase of Saccharomyces cerevisiae (ScMCA-Ia) presents different catalytic cysteine in a processed and non-processed form<br>Biochem Biophys Res Commun (2023) 687, 149185-149185. PubMed  Europe PubMed DOI
  3. Eisele-Burger,A.M., Eisele,F., Malmgren Hill,S., Hao,X., Schneider,K.L., Imamoglu,R., Balchin,D., Liu,B., Hartl,F.U., Bozhkov,P.V. and Nystrom,T.<br>Calmodulin regulates protease versus co-chaperone activity of a metacaspase<br>Cell Rep (2023) 42, 113372-113372. PubMed  Europe PubMed DOI
  4. Kaushal,V., Klim,J., Skoneczna,A., Kurlandzka,A., Enkhbaatar,T., Kaczanowski,S. and Zielenkiewicz,U.<br>Apoptotic Factors Are Evolutionarily Conserved Since Mitochondrial Domestication<br>Genome Biol Evol (2023) 15 PubMed  Europe PubMed DOI  PMC  EPMC
  5. Lam,D.K. and Sherlock,G.<br>Yca1 metacaspase: diverse functions determine how yeast live and let die<br>FEMS Yeast Res (2023) 23 PubMed  Europe PubMed DOI  PMC  EPMC
    6. 2022
  6. Conchou,L., Doumeche,B., Galisson,F., Violot,S., Dugelay,C., Diesis,E., Page,A., Bienvenu,A.L., Picot,S., Aghajari,N. and Ballut,L.<br>Structural and molecular determinants of Candida glabrata metacaspase maturation and activation by calcium<br>Commun Biol (2022) 5, 1158-1158. PubMed  Europe PubMed DOI  PMC  EPMC
    7. 2021
  7. Fernandez,J., Lopez,V., Kinch,L., Pfeifer,M.A., Gray,H., Garcia,N., Grishin,N.V., Khang,C.H. and Orth,K.<br>Role of Two Metacaspases in Development and Pathogenicity of the Rice Blast Fungus Magnaporthe oryzae<br>MBio (2021) 12 PubMed  Europe PubMed DOI  PMC  EPMC
  8. Scariot,F.J., Pansera,M.S., Delamare,A.P.L. and Echeverrigaray,S.<br>Citral and geraniol induce necrotic and apoptotic cell death on Saccharomyces cerevisiae<br>World J Microbiol Biotechnol (2021) 37, 42-42. PubMed  Europe PubMed DOI
    9. 2019
  9. Leang,L., McDonald,M.C., Mineo,C.R., Jones,B., Barker,T., Gagliardi,C. and Fox,K.M.<br>Identification and characterization of Schizophyllum commune type I metacaspases<br>Biochem Biophys Rep (2019) 20, 100706-100706. PubMed  Europe PubMed DOI  PMC  EPMC
  10. Shrestha,A., Brunette,S., Stanford,W.L. and Megeney,L.A.<br>The metacaspase Yca1 maintains proteostasis through multiple interactions with the ubiquitin system<br>Cell Discov (2019) 5, 6-6. PubMed  Europe PubMed DOI  PMC  EPMC
    11. 2016
  11. Jeong,J.-H., Lee,S.-E. and Kim,J.<br>Mutational analysis of metacaspase CaMca1 and decapping activator Edc3 in the pathogenicity of Candida albicans<br>Fungal Genet Biol (2016) 97, 18-23. PubMed  Europe PubMed DOI
  12. Laprade,D.J., Brown,M.S., McCarthy,M.L., Ritch,J.J. and Austriaco,N.<br>Filamentation protects Candida albicans from amphotericin B-induced programmed cell death via a mechanism involving the yeast metacaspase, MCA1<br>Microb Cell (2016) 3, 285-292. PubMed  Europe PubMed DOI
  13. Leger,T., Garcia,C. and Camadro,J.M.<br>The metacaspase (Mca1p) restricts O-glycosylation during farnesol-induced apoptosis in Candida albicans<br>Mol Cell Proteomics (2016) 15, 2308-2323. PubMed  Europe PubMed DOI
    14. 2015
  14. Hill,S.M. and Nystrom,T.<br>The dual role of a yeast metacaspase: what doesn't kill you makes you stronger<br>Bioessays (2015) 37, 525-531. PubMed  Europe PubMed DOI
  15. Leger,T., Garcia,C., Ounissi,M., Lelandais,G. and Camadro,J.M.<br>The metacaspase (Mca1p) has a dual role in farnesol-induced apoptosis in Candida albicans<br>Mol Cell Proteomics (2015) 14, 93-108. PubMed  Europe PubMed DOI  P
  16. Longo,V., Zdralevic,M., Guaragnella,N., Giannattasio,S., Zolla,L. and Timperio,A.M.<br>Proteome and metabolome profiling of wild-type and YCA1-knock-out yeast cells during acetic acid-induced programmed cell death<br>J Proteomics (2015) 128, 173-188. PubMed  Europe PubMed DOI
  17. Zdralevic,M., Longo,V., Guaragnella,N., Giannattasio,S., Timperio,A.M. and Zolla,L.<br>Differential proteome-metabolome profiling of YCA1-knock-out and wild type cells reveals novel metabolic pathways and cellular processes dependent on the yeast metacaspase<br>Mol Biosyst (2015) 11, 1573-1583. PubMed  Europe PubMed DOI  K
    18. 2014
  18. Biswas,C., Zuo,X., Chen,S.C., Schibeci,S.D., Forwood,J.K., Jolliffe,K.A., Sorrell,T.C. and Djordjevic,J.T.<br>Functional disruption of yeast metacaspase, Mca1, leads to miltefosine resistance and inability to mediate miltefosine-induced apoptotic effects<br>Fungal Genet Biol (2014) 67, 71-81. PubMed  Europe PubMed DOI  K
  19. Hill,S.M., Hao,X., Liu,B. and Nystrom,T.<br>Life-span extension by a metacaspase in the yeast Saccharomyces cerevisiae<br>Science (2014) 344, 1389-1392. PubMed  Europe PubMed DOI
  20. Hurtley,S.M.<br>Yeast metacaspase: grim reaper or savior?<br>Sci Signal (2014) 7, ec175-ec175. DOI
  21. Joshi,R.S., Tanpure,R.S., Singh,R.K., Gupta,V.S. and Giri,A.P.<br>Resistance through inhibition: ectopic expression of serine protease inhibitor offers stress tolerance via delayed senescence in yeast cell<br>Biochem Biophys Res Commun (2014) 452, 361-368. PubMed  Europe PubMed DOI
  22. Jung,J.H. and Kim,J.<br>Roles of Edc3 in the oxidative stress response and CaMCA1-encoded metacaspase expression in Candida albicans<br>FEBS J (2014) 281, 4841-4851. PubMed  Europe PubMed DOI
  23. Liu,B.<br>The yin and yang of a metacaspase<br>Cell Cycle (2014) 13, 3471-3472. PubMed  Europe PubMed DOI
  24. Shrestha,A., Lee,R.E. and Megeney,L.A.<br>Monitoring the proteostasis function of the Saccharomyces cerevisiae metacaspase Yca1<br>Methods Mol Biol (2014) 1133, 223-235. PubMed  Europe PubMed DOI
    25. 2013
  25. Greetham,D., Kritsiligkou,P., Watkins,R.H., Carter,Z., Parkin,J. and Grant,C.M.<br>Oxidation of the yeast mitochondrial thioredoxin promotes cell death<br>Antioxid Redox Signal (2013) 18, 376-385. PubMed  Europe PubMed DOI
  26. Shrestha,A., Puente,L.G., Brunette,S. and Megeney,L.A.<br>The role of Yca1 in proteostasis. Yca1 regulates the composition of the insoluble proteome<br>J Proteomics (2013) 81, 24-30. PubMed  Europe PubMed DOI
    27. 2012
  27. Antonacci,L., Guaragnella,N., Zdralevic,M., Passarella,S., Marra,E. and Giannattasio,S.<br>The N-Acetylcysteine-insensitive acetic acid-induced yeast programmed cell death occurs without macroautophagy<br>Curr Pharm Biotechnol (2012) 13, 2705-2711. PubMed  Europe PubMed DOI
  28. Ojha,M.<br>Fungal metacaspases<br>[ISSN:978-0-12-407743-0] (2012) 3, 2304-2309. DOI
  29. Wong,A.H., Yan,C. and Shi,Y.<br>Crystal structure of the yeast metacaspase Yca1<br>J Biol Chem (2012) 287, 29251-29259. PubMed  Europe PubMed DOI  S
    30. 2011
  30. Silva,A., Almeida,B., Sampaio-Marques,B., Reis,M.I., Ohlmeier,S., Rodrigues,F., Vale,A.D. and Ludovico,P.<br>Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a specific substrate of yeast metacaspase<br>Biochim Biophys Acta (2011) 1813, 2044-2049. PubMed  Europe PubMed DOI
  31. Tsiatsiani,L., Van Breusegem,F., Gallois,P., Zavialov,A., Lam,E. and Bozhkov,P.V.<br>Metacaspases<br>Cell Death Differ (2011) 18, 1279-1288. PubMed  Europe PubMed DOI  V
    32. 2010
  32. Bozhkov,P.V., Smertenko,A.P. and Zhivotovsky,B.<br>Aspasing out metacaspases and caspases: proteases of many trades<br>Sci Signal (2010) 3, pe48- PubMed  Europe PubMed DOI
  33. Du,L., Lu,Y. and Zhou,S.<br>Yeast caspase 1, a possible antioxidant enzyme belonging to a mitochondrial originated antioxidation process<br>ICBBT - Int Conf Bioinformatics Biomed Technol (2010) 16-18 April 2010, 153-155. DOI
  34. Erhardt,M., Wegrzyn,R.D. and Deuerling,E.<br>Extra N-terminal residues have a profound effect on the aggregation properties of the potential yeast prion protein Mca1<br>PLoS ONE (2010) 5, e9929-e9929. PubMed  Europe PubMed DOI  PMC  EPMC
  35. Guaragnella,N., Bobba,A., Passarella,S., Marra,E. and Giannattasio,S.<br>Yeast acetic acid-induced programmed cell death can occur without cytochrome c release which requires metacaspase YCA1<br>FEBS Lett (2010) 584, 224-228. PubMed  Europe PubMed DOI
  36. Lee,R.E., Brunette,S., Puente,L.G. and Megeney,L.A.<br>Metacaspase Yca1 is required for clearance of insoluble protein aggregates<br>Proc Natl Acad Sci U S A (2010) 107, 13348-13353. PubMed  Europe PubMed DOI
  37. Mousavi,S.A.A. and Robson,G.D.<br>Cloning of metacaspase gene expressed in the opportunistic human pathogenic fungus, Aspergillus fumigatus<br>Jundishapur J Microbiol (2010) 3, 71-78.
  38. Ojha,M., Cattaneo,A., Hugh,S., Pawlowski,J. and Cox,J.A.<br>Structure, expression and function of Allomyces arbuscula CDP II (metacaspase) gene<br>Gene (2010) 457, 25-34. PubMed  Europe PubMed DOI  P
    39. 2009
  39. Cao,Y., Huang,S., Dai,B., Zhu,Z., Lu,H., Dong,L., Cao,Y., Wang,Y., Gao,P., Chai,Y. and Jiang,Y.<br>Candida albicans cells lacking CaMCA1-encoded metacaspase show resistance to oxidative stress-induced death and change in energy metabolism<br>Fungal Genet Biol (2009) 46, 183-189. PubMed  Europe PubMed DOI  K
    40. 2008
  40. Lee,R.E., Puente,L.G., Kaern,M. and Megeney,L.A.<br>A non-death role of the yeast metacaspase: Yca1p alters cell cycle dynamics<br>PLoS ONE (2008) 3, e2956-e2956. PubMed  Europe PubMed DOI  PMC  EPMC
  41. Liang,Q., Li,W. and Zhou,B.<br>Caspase-independent apoptosis in yeast<br>Biochim Biophys Acta (2008) 1783, 1311-1319. PubMed  Europe PubMed DOI  V
  42. Mazzoni,C. and Falcone,C.<br>Caspase-dependent apoptosis in yeast<br>Biochim Biophys Acta (2008) 1783, 1320-1327. PubMed  Europe PubMed DOI  V
    43. 2007
  43. Hamann,A., Brust,D. and Osiewacz,H.D.<br>Deletion of putative apoptosis factors leads to lifespan extension in the fungal ageing model Podospora anserina<br>Mol Microbiol (2007) 65, 948-958. PubMed  Europe PubMed DOI
  44. Lim,H.W., Kim,S.J., Park,E.H. and Lim,C.J.<br>Overexpression of a metacaspase gene stimulates cell growth and stress response in Schizosaccharomyces pombe<br>Can J Microbiol (2007) 53, 1016-1023. PubMed  Europe PubMed DOI
  45. Richie,D.L., Miley,M.D., Bhabhra,R., Robson,G.D., Rhodes,J.C. and Askew,D.S.<br>The Aspergillus fumigatus metacaspases CasA and CasB facilitate growth under conditions of endoplasmic reticulum stress<br>Mol Microbiol (2007) 63, 591-604. PubMed  Europe PubMed DOI
  46. Vachova,L. and Palkova,Z.<br>Caspases in yeast apoptosis-like death: facts and artefacts<br>FEMS Yeast Res (2007) 7, 12-21. PubMed  Europe PubMed DOI  V
  47. Vercammen,D., Declercq,W., Vandenabeele,P. and Van Breusegem,F.<br>Are metacaspases caspases?<br>J Cell Biol (2007) 179, 375-380. PubMed  Europe PubMed DOI  PMC  EPMC  V
    48. 2006
  48. [YEAR:12-9-2006]Cotado-Sampayo,M., Ojha,M., Ortega-Perez,R., Chappuis,M.L. and Barja,F.<br>Proteolytic cleavage of a spectrin-related protein by calcium-dependent protease in Neurospora crassa<br>Curr Microbiol (12-9-2006) 53, 311-316. PubMed  Europe PubMed DOI
  49. [YEAR:22-12-2006]Guaragnella,N., Pereira,C., Sousa,M.J., Antonacci,L., Passarella,S., Corte-Real,M., Marra,E. and Giannattasio,S.<br>YCA1 participates in the acetic acid induced yeast programmed cell death also in a manner unrelated to its caspase-like activity<br>FEBS Lett (22-12-2006) 580, 6880-6884. PubMed  Europe PubMed DOI
    50. 2005
  50. [YEAR:29-11-2005]Khan,M.A., Chock,P.B. and Stadtman,E.R.<br>Knockout of caspase-like gene, YCA1, abrogates apoptosis and elevates oxidized proteins in Saccharomyces cerevisiae<br>Proc Natl Acad Sci U S A (29-11-2005) 102, 17326-17331. PubMed  Europe PubMed DOI  PMC  EPMC  K
  51. Silva,R.D., Sotoca,R., Johansson,B., Ludovico,P., Sansonetty,F., Silva,M.T., Peinado,J.M. and Corte-Real,M.<br>Hyperosmotic stress induces metacaspase- and mitochondria-dependent apoptosis in Saccharomyces cerevisiae<br>Mol Microbiol (2005) 58, 824-834. PubMed  Europe PubMed DOI
  52. Vachova,L. and Palkova,Z.<br>Physiological regulation of yeast cell death in multicellular colonies is triggered by ammonia<br>J Cell Biol (2005) 169, 711-717. PubMed  Europe PubMed DOI  PMC  EPMC
    53. 2004
  53. Bettiga,M., Calzari,L., Orlandi,I., Alberghina,L. and Vai,M.<br>Involvement of the yeast metacaspase Yca1 in ubp10Delta-programmed cell death<br>FEMS Yeast Res (2004) 5, 141-147. PubMed  Europe PubMed DOI
  54. [YEAR:16-2-2004]Herker,E., Jungwirth,H., Lehmann,K.A., Maldener,C., Frohlich,K.U., Wissing,S., Buttner,S., Fehr,M., Sigrist,S. and Madeo,F.<br>Chronological aging leads to apoptosis in yeast<br>J Cell Biol (16-2-2004) 164, 501-507. PubMed  Europe PubMed DOI  PMC  EPMC
  55. [YEAR:4-5-2004]Suarez,M.F., Filonova,L.H., Smertenko,A., Savenkov,E.I., Clapham,D.H., von Arnold,S., Zhivotovsky,B. and Bozhkov,P.V.<br>Metacaspase-dependent programmed cell death is essential for plant embryogenesis<br>Curr Biol (4-5-2004) 14, R339-R340. PubMed  Europe PubMed DOI
  56. Wadskog,I., Maldener,C., Proksch,A., Madeo,F. and Adler,L.<br>Yeast lacking the SRO7/SOP1-encoded tumor suppressor homologue show increased susceptibility to apoptosis-like cell death on exposure to NaCl stress<br>Mol Biol Cell (2004) 15, 1436-1444. PubMed  Europe PubMed DOI  PMC  EPMC
  57. [YEAR:2-8-2004]Wysocki,R. and Kron,S.J.<br>Yeast cell death during DNA damage arrest is independent of caspase or reactive oxygen species<br>J Cell Biol (2-8-2004) 166, 311-316. PubMed  Europe PubMed DOI  PMC  EPMC
    58. 2003
  58. [YEAR:15-3-2003]Ojha,M. and Barja,F.<br>Spatial and cellular localization of calcium-dependent protease (CDP II) in Allomyces arbuscula<br>J Cell Sci (15-3-2003) 116, 1095-1105. PubMed  Europe PubMed DOI
    59. 2002
  59. Madeo,F., Engelhardt,S., Herker,E., Lehmann,N., Maldener,C., Proksch,A., Wissing,S. and Frohlich,K.U.<br>Apoptosis in yeast: a new model system with applications in cell biology and medicine<br>Curr Genet (2002) 41, 208-216. PubMed  Europe PubMed DOI
  60. Madeo,F., Herker,E., Maldener,C., Wissing,S., Lachelt,S., Herlan,M., Fehr,M., Lauber,K., Sigrist,S.J., Wesselborg,S. and Frohlich,K.U.<br>A caspase-related protease regulates apoptosis in yeast<br>Mol Cell (2002) 9, 911-917. PubMed  Europe PubMed DOI
    61. 1999
  61. Barja,F., Jaquet,Y., Perez,R.O., Hoch,H.C. and Ojha,M.<br>Identification and localization of calcium-dependent protease II in Neurospora crassa and Uromyces appendiculatus<br>Protoplasma (1999) 210, 85-91.
  62. Ojha,M., Cattaneo,A. and Schwendimann,B.<br>Comparative studies of Ca2+-dependent proteases (CDP I and CDP II) from Allomyces arbuscula<br>Biochimie (1999) 81, 765-770. PubMed  Europe PubMed DOI  P
    63. 1996
  63. Ojha,M.<br>Ca(2+)-dependent protease I from Allomyces arbuscula<br>Biochem Biophys Res Commun (1996) 218, 22-29. PubMed  Europe PubMed DOI
  64. Ojha,M.<br>Purification, properties and developmental regulation of a Ca(2+)-independent serine-cysteine protease from Allomyces arbuscula<br>Int J Biochem Cell Biol (1996) 28, 345-352. PubMed  Europe PubMed DOI
    65. 1991
  65. Ojha,M. and Favre,B.<br>In vitro and in vivo phosphorylation of calpain-like protease of Allomyces arbuscula<br>Plant Sci (1991) 74, 35-44.
    66. 1989
  66. Ojha,M.<br>Allomyces Ca2+-activated neutral protease: interaction with phospholipids and plasma membranes<br>Plant Sci (1989) 59, 151-158.
    67. 1988
  67. Ojha,M. and Wallace,C.J.<br>Novel Ca2+-activated neutral protease from an aquatic fungus, Allomyces arbuscula<br>J Bacteriol (1988) 170, 1254-1260. PubMed  Europe PubMed  PMC  EPMC

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