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Literature for peptidase C14.035: metacaspase Yca1 (Saccharomyces cerevisiae-type)

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors

(Topics flags: S Structure, K Knockout, P Specificity, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2024
  1. Bienvenu,A.L., Ballut,L. and Picot,S.
    Specifically Targeting Metacaspases of Candida: A New Therapeutic Opportunity
    J Fungi (Basel) (2024) 10 PubMed  Europe PubMed DOI  PMC  EPMC  V
    2. 2023
  2. Dalzoto,L.A.M., Trujilho,M.N.R., Santos,T.D.R., Costa,J.P.M.S., Duarte,A.C.M., Judice,W.A.S., Marcondes,M.F. and Machado,M.F.M.
    Metacaspase of Saccharomyces cerevisiae (ScMCA-Ia) presents different catalytic cysteine in a processed and non-processed form
    Biochem Biophys Res Commun (2023) 687, 149185-149185. PubMed  Europe PubMed DOI
  3. Eisele-Burger,A.M., Eisele,F., Malmgren Hill,S., Hao,X., Schneider,K.L., Imamoglu,R., Balchin,D., Liu,B., Hartl,F.U., Bozhkov,P.V. and Nystrom,T.
    Calmodulin regulates protease versus co-chaperone activity of a metacaspase
    Cell Rep (2023) 42, 113372-113372. PubMed  Europe PubMed DOI
  4. Kaushal,V., Klim,J., Skoneczna,A., Kurlandzka,A., Enkhbaatar,T., Kaczanowski,S. and Zielenkiewicz,U.
    Apoptotic Factors Are Evolutionarily Conserved Since Mitochondrial Domestication
    Genome Biol Evol (2023) 15 PubMed  Europe PubMed DOI  PMC  EPMC
  5. Lam,D.K. and Sherlock,G.
    Yca1 metacaspase: diverse functions determine how yeast live and let die
    FEMS Yeast Res (2023) 23 PubMed  Europe PubMed DOI  PMC  EPMC
    6. 2022
  6. Conchou,L., Doumeche,B., Galisson,F., Violot,S., Dugelay,C., Diesis,E., Page,A., Bienvenu,A.L., Picot,S., Aghajari,N. and Ballut,L.
    Structural and molecular determinants of Candida glabrata metacaspase maturation and activation by calcium
    Commun Biol (2022) 5, 1158-1158. PubMed  Europe PubMed DOI  PMC  EPMC
    7. 2021
  7. Fernandez,J., Lopez,V., Kinch,L., Pfeifer,M.A., Gray,H., Garcia,N., Grishin,N.V., Khang,C.H. and Orth,K.
    Role of Two Metacaspases in Development and Pathogenicity of the Rice Blast Fungus Magnaporthe oryzae
    MBio (2021) 12 PubMed  Europe PubMed DOI  PMC  EPMC
  8. Scariot,F.J., Pansera,M.S., Delamare,A.P.L. and Echeverrigaray,S.
    Citral and geraniol induce necrotic and apoptotic cell death on Saccharomyces cerevisiae
    World J Microbiol Biotechnol (2021) 37, 42-42. PubMed  Europe PubMed DOI
    9. 2019
  9. Leang,L., McDonald,M.C., Mineo,C.R., Jones,B., Barker,T., Gagliardi,C. and Fox,K.M.
    Identification and characterization of Schizophyllum commune type I metacaspases
    Biochem Biophys Rep (2019) 20, 100706-100706. PubMed  Europe PubMed DOI  PMC  EPMC
  10. Shrestha,A., Brunette,S., Stanford,W.L. and Megeney,L.A.
    The metacaspase Yca1 maintains proteostasis through multiple interactions with the ubiquitin system
    Cell Discov (2019) 5, 6-6. PubMed  Europe PubMed DOI  PMC  EPMC
    11. 2016
  11. Jeong,J.-H., Lee,S.-E. and Kim,J.
    Mutational analysis of metacaspase CaMca1 and decapping activator Edc3 in the pathogenicity of Candida albicans
    Fungal Genet Biol (2016) 97, 18-23. PubMed  Europe PubMed DOI
  12. Laprade,D.J., Brown,M.S., McCarthy,M.L., Ritch,J.J. and Austriaco,N.
    Filamentation protects Candida albicans from amphotericin B-induced programmed cell death via a mechanism involving the yeast metacaspase, MCA1
    Microb Cell (2016) 3, 285-292. PubMed  Europe PubMed DOI
  13. Leger,T., Garcia,C. and Camadro,J.M.
    The metacaspase (Mca1p) restricts O-glycosylation during farnesol-induced apoptosis in Candida albicans
    Mol Cell Proteomics (2016) 15, 2308-2323. PubMed  Europe PubMed DOI
    14. 2015
  14. Hill,S.M. and Nystrom,T.
    The dual role of a yeast metacaspase: what doesn't kill you makes you stronger
    Bioessays (2015) 37, 525-531. PubMed  Europe PubMed DOI
  15. Leger,T., Garcia,C., Ounissi,M., Lelandais,G. and Camadro,J.M.
    The metacaspase (Mca1p) has a dual role in farnesol-induced apoptosis in Candida albicans
    Mol Cell Proteomics (2015) 14, 93-108. PubMed  Europe PubMed DOI  P
  16. Longo,V., Zdralevic,M., Guaragnella,N., Giannattasio,S., Zolla,L. and Timperio,A.M.
    Proteome and metabolome profiling of wild-type and YCA1-knock-out yeast cells during acetic acid-induced programmed cell death
    J Proteomics (2015) 128, 173-188. PubMed  Europe PubMed DOI
  17. Zdralevic,M., Longo,V., Guaragnella,N., Giannattasio,S., Timperio,A.M. and Zolla,L.
    Differential proteome-metabolome profiling of YCA1-knock-out and wild type cells reveals novel metabolic pathways and cellular processes dependent on the yeast metacaspase
    Mol Biosyst (2015) 11, 1573-1583. PubMed  Europe PubMed DOI  K
    18. 2014
  18. Biswas,C., Zuo,X., Chen,S.C., Schibeci,S.D., Forwood,J.K., Jolliffe,K.A., Sorrell,T.C. and Djordjevic,J.T.
    Functional disruption of yeast metacaspase, Mca1, leads to miltefosine resistance and inability to mediate miltefosine-induced apoptotic effects
    Fungal Genet Biol (2014) 67, 71-81. PubMed  Europe PubMed DOI  K
  19. Hill,S.M., Hao,X., Liu,B. and Nystrom,T.
    Life-span extension by a metacaspase in the yeast Saccharomyces cerevisiae
    Science (2014) 344, 1389-1392. PubMed  Europe PubMed DOI
  20. Hurtley,S.M.
    Yeast metacaspase: grim reaper or savior?
    Sci Signal (2014) 7, ec175-ec175. DOI
  21. Joshi,R.S., Tanpure,R.S., Singh,R.K., Gupta,V.S. and Giri,A.P.
    Resistance through inhibition: ectopic expression of serine protease inhibitor offers stress tolerance via delayed senescence in yeast cell
    Biochem Biophys Res Commun (2014) 452, 361-368. PubMed  Europe PubMed DOI
  22. Jung,J.H. and Kim,J.
    Roles of Edc3 in the oxidative stress response and CaMCA1-encoded metacaspase expression in Candida albicans
    FEBS J (2014) 281, 4841-4851. PubMed  Europe PubMed DOI
  23. Liu,B.
    The yin and yang of a metacaspase
    Cell Cycle (2014) 13, 3471-3472. PubMed  Europe PubMed DOI
  24. Shrestha,A., Lee,R.E. and Megeney,L.A.
    Monitoring the proteostasis function of the Saccharomyces cerevisiae metacaspase Yca1
    Methods Mol Biol (2014) 1133, 223-235. PubMed  Europe PubMed DOI
    25. 2013
  25. Greetham,D., Kritsiligkou,P., Watkins,R.H., Carter,Z., Parkin,J. and Grant,C.M.
    Oxidation of the yeast mitochondrial thioredoxin promotes cell death
    Antioxid Redox Signal (2013) 18, 376-385. PubMed  Europe PubMed DOI
  26. Shrestha,A., Puente,L.G., Brunette,S. and Megeney,L.A.
    The role of Yca1 in proteostasis. Yca1 regulates the composition of the insoluble proteome
    J Proteomics (2013) 81, 24-30. PubMed  Europe PubMed DOI
    27. 2012
  27. Antonacci,L., Guaragnella,N., Zdralevic,M., Passarella,S., Marra,E. and Giannattasio,S.
    The N-Acetylcysteine-insensitive acetic acid-induced yeast programmed cell death occurs without macroautophagy
    Curr Pharm Biotechnol (2012) 13, 2705-2711. PubMed  Europe PubMed DOI
  28. Ojha,M.
    Fungal metacaspases
    [ISSN:978-0-12-407743-0] (2012) 3, 2304-2309. DOI
  29. Wong,A.H., Yan,C. and Shi,Y.
    Crystal structure of the yeast metacaspase Yca1
    J Biol Chem (2012) 287, 29251-29259. PubMed  Europe PubMed DOI  S
    30. 2011
  30. Silva,A., Almeida,B., Sampaio-Marques,B., Reis,M.I., Ohlmeier,S., Rodrigues,F., Vale,A.D. and Ludovico,P.
    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a specific substrate of yeast metacaspase
    Biochim Biophys Acta (2011) 1813, 2044-2049. PubMed  Europe PubMed DOI
  31. Tsiatsiani,L., Van Breusegem,F., Gallois,P., Zavialov,A., Lam,E. and Bozhkov,P.V.
    Metacaspases
    Cell Death Differ (2011) 18, 1279-1288. PubMed  Europe PubMed DOI  V
    32. 2010
  32. Bozhkov,P.V., Smertenko,A.P. and Zhivotovsky,B.
    Aspasing out metacaspases and caspases: proteases of many trades
    Sci Signal (2010) 3, pe48- PubMed  Europe PubMed DOI
  33. Du,L., Lu,Y. and Zhou,S.
    Yeast caspase 1, a possible antioxidant enzyme belonging to a mitochondrial originated antioxidation process
    ICBBT - Int Conf Bioinformatics Biomed Technol (2010) 16-18 April 2010, 153-155. DOI
  34. Erhardt,M., Wegrzyn,R.D. and Deuerling,E.
    Extra N-terminal residues have a profound effect on the aggregation properties of the potential yeast prion protein Mca1
    PLoS ONE (2010) 5, e9929-e9929. PubMed  Europe PubMed DOI  PMC  EPMC
  35. Guaragnella,N., Bobba,A., Passarella,S., Marra,E. and Giannattasio,S.
    Yeast acetic acid-induced programmed cell death can occur without cytochrome c release which requires metacaspase YCA1
    FEBS Lett (2010) 584, 224-228. PubMed  Europe PubMed DOI
  36. Lee,R.E., Brunette,S., Puente,L.G. and Megeney,L.A.
    Metacaspase Yca1 is required for clearance of insoluble protein aggregates
    Proc Natl Acad Sci U S A (2010) 107, 13348-13353. PubMed  Europe PubMed DOI
  37. Mousavi,S.A.A. and Robson,G.D.
    Cloning of metacaspase gene expressed in the opportunistic human pathogenic fungus, Aspergillus fumigatus
    Jundishapur J Microbiol (2010) 3, 71-78.
  38. Ojha,M., Cattaneo,A., Hugh,S., Pawlowski,J. and Cox,J.A.
    Structure, expression and function of Allomyces arbuscula CDP II (metacaspase) gene
    Gene (2010) 457, 25-34. PubMed  Europe PubMed DOI  P
    39. 2009
  39. Cao,Y., Huang,S., Dai,B., Zhu,Z., Lu,H., Dong,L., Cao,Y., Wang,Y., Gao,P., Chai,Y. and Jiang,Y.
    Candida albicans cells lacking CaMCA1-encoded metacaspase show resistance to oxidative stress-induced death and change in energy metabolism
    Fungal Genet Biol (2009) 46, 183-189. PubMed  Europe PubMed DOI  K
    40. 2008
  40. Lee,R.E., Puente,L.G., Kaern,M. and Megeney,L.A.
    A non-death role of the yeast metacaspase: Yca1p alters cell cycle dynamics
    PLoS ONE (2008) 3, e2956-e2956. PubMed  Europe PubMed DOI  PMC  EPMC
  41. Liang,Q., Li,W. and Zhou,B.
    Caspase-independent apoptosis in yeast
    Biochim Biophys Acta (2008) 1783, 1311-1319. PubMed  Europe PubMed DOI  V
  42. Mazzoni,C. and Falcone,C.
    Caspase-dependent apoptosis in yeast
    Biochim Biophys Acta (2008) 1783, 1320-1327. PubMed  Europe PubMed DOI  V
    43. 2007
  43. Hamann,A., Brust,D. and Osiewacz,H.D.
    Deletion of putative apoptosis factors leads to lifespan extension in the fungal ageing model Podospora anserina
    Mol Microbiol (2007) 65, 948-958. PubMed  Europe PubMed DOI
  44. Lim,H.W., Kim,S.J., Park,E.H. and Lim,C.J.
    Overexpression of a metacaspase gene stimulates cell growth and stress response in Schizosaccharomyces pombe
    Can J Microbiol (2007) 53, 1016-1023. PubMed  Europe PubMed DOI
  45. Richie,D.L., Miley,M.D., Bhabhra,R., Robson,G.D., Rhodes,J.C. and Askew,D.S.
    The Aspergillus fumigatus metacaspases CasA and CasB facilitate growth under conditions of endoplasmic reticulum stress
    Mol Microbiol (2007) 63, 591-604. PubMed  Europe PubMed DOI
  46. Vachova,L. and Palkova,Z.
    Caspases in yeast apoptosis-like death: facts and artefacts
    FEMS Yeast Res (2007) 7, 12-21. PubMed  Europe PubMed DOI  V
  47. Vercammen,D., Declercq,W., Vandenabeele,P. and Van Breusegem,F.
    Are metacaspases caspases?
    J Cell Biol (2007) 179, 375-380. PubMed  Europe PubMed DOI  PMC  EPMC  V
    48. 2006
  48. [YEAR:12-9-2006]Cotado-Sampayo,M., Ojha,M., Ortega-Perez,R., Chappuis,M.L. and Barja,F.
    Proteolytic cleavage of a spectrin-related protein by calcium-dependent protease in Neurospora crassa
    Curr Microbiol (12-9-2006) 53, 311-316. PubMed  Europe PubMed DOI
  49. [YEAR:22-12-2006]Guaragnella,N., Pereira,C., Sousa,M.J., Antonacci,L., Passarella,S., Corte-Real,M., Marra,E. and Giannattasio,S.
    YCA1 participates in the acetic acid induced yeast programmed cell death also in a manner unrelated to its caspase-like activity
    FEBS Lett (22-12-2006) 580, 6880-6884. PubMed  Europe PubMed DOI
    50. 2005
  50. [YEAR:29-11-2005]Khan,M.A., Chock,P.B. and Stadtman,E.R.
    Knockout of caspase-like gene, YCA1, abrogates apoptosis and elevates oxidized proteins in Saccharomyces cerevisiae
    Proc Natl Acad Sci U S A (29-11-2005) 102, 17326-17331. PubMed  Europe PubMed DOI  PMC  EPMC  K
  51. Silva,R.D., Sotoca,R., Johansson,B., Ludovico,P., Sansonetty,F., Silva,M.T., Peinado,J.M. and Corte-Real,M.
    Hyperosmotic stress induces metacaspase- and mitochondria-dependent apoptosis in Saccharomyces cerevisiae
    Mol Microbiol (2005) 58, 824-834. PubMed  Europe PubMed DOI
  52. Vachova,L. and Palkova,Z.
    Physiological regulation of yeast cell death in multicellular colonies is triggered by ammonia
    J Cell Biol (2005) 169, 711-717. PubMed  Europe PubMed DOI  PMC  EPMC
    53. 2004
  53. Bettiga,M., Calzari,L., Orlandi,I., Alberghina,L. and Vai,M.
    Involvement of the yeast metacaspase Yca1 in ubp10Delta-programmed cell death
    FEMS Yeast Res (2004) 5, 141-147. PubMed  Europe PubMed DOI
  54. [YEAR:16-2-2004]Herker,E., Jungwirth,H., Lehmann,K.A., Maldener,C., Frohlich,K.U., Wissing,S., Buttner,S., Fehr,M., Sigrist,S. and Madeo,F.
    Chronological aging leads to apoptosis in yeast
    J Cell Biol (16-2-2004) 164, 501-507. PubMed  Europe PubMed DOI  PMC  EPMC
  55. [YEAR:4-5-2004]Suarez,M.F., Filonova,L.H., Smertenko,A., Savenkov,E.I., Clapham,D.H., von Arnold,S., Zhivotovsky,B. and Bozhkov,P.V.
    Metacaspase-dependent programmed cell death is essential for plant embryogenesis
    Curr Biol (4-5-2004) 14, R339-R340. PubMed  Europe PubMed DOI
  56. Wadskog,I., Maldener,C., Proksch,A., Madeo,F. and Adler,L.
    Yeast lacking the SRO7/SOP1-encoded tumor suppressor homologue show increased susceptibility to apoptosis-like cell death on exposure to NaCl stress
    Mol Biol Cell (2004) 15, 1436-1444. PubMed  Europe PubMed DOI  PMC  EPMC
  57. [YEAR:2-8-2004]Wysocki,R. and Kron,S.J.
    Yeast cell death during DNA damage arrest is independent of caspase or reactive oxygen species
    J Cell Biol (2-8-2004) 166, 311-316. PubMed  Europe PubMed DOI  PMC  EPMC
    58. 2003
  58. [YEAR:15-3-2003]Ojha,M. and Barja,F.
    Spatial and cellular localization of calcium-dependent protease (CDP II) in Allomyces arbuscula
    J Cell Sci (15-3-2003) 116, 1095-1105. PubMed  Europe PubMed DOI
    59. 2002
  59. Madeo,F., Engelhardt,S., Herker,E., Lehmann,N., Maldener,C., Proksch,A., Wissing,S. and Frohlich,K.U.
    Apoptosis in yeast: a new model system with applications in cell biology and medicine
    Curr Genet (2002) 41, 208-216. PubMed  Europe PubMed DOI
  60. Madeo,F., Herker,E., Maldener,C., Wissing,S., Lachelt,S., Herlan,M., Fehr,M., Lauber,K., Sigrist,S.J., Wesselborg,S. and Frohlich,K.U.
    A caspase-related protease regulates apoptosis in yeast
    Mol Cell (2002) 9, 911-917. PubMed  Europe PubMed DOI
    61. 1999
  61. Barja,F., Jaquet,Y., Perez,R.O., Hoch,H.C. and Ojha,M.
    Identification and localization of calcium-dependent protease II in Neurospora crassa and Uromyces appendiculatus
    Protoplasma (1999) 210, 85-91.
  62. Ojha,M., Cattaneo,A. and Schwendimann,B.
    Comparative studies of Ca2+-dependent proteases (CDP I and CDP II) from Allomyces arbuscula
    Biochimie (1999) 81, 765-770. PubMed  Europe PubMed DOI  P
    63. 1996
  63. Ojha,M.
    Ca(2+)-dependent protease I from Allomyces arbuscula
    Biochem Biophys Res Commun (1996) 218, 22-29. PubMed  Europe PubMed DOI
  64. Ojha,M.
    Purification, properties and developmental regulation of a Ca(2+)-independent serine-cysteine protease from Allomyces arbuscula
    Int J Biochem Cell Biol (1996) 28, 345-352. PubMed  Europe PubMed DOI
    65. 1991
  65. Ojha,M. and Favre,B.
    In vitro and in vivo phosphorylation of calpain-like protease of Allomyces arbuscula
    Plant Sci (1991) 74, 35-44.
    66. 1989
  66. Ojha,M.
    Allomyces Ca2+-activated neutral protease: interaction with phospholipids and plasma membranes
    Plant Sci (1989) 59, 151-158.
    67. 1988
  67. Ojha,M. and Wallace,C.J.
    Novel Ca2+-activated neutral protease from an aquatic fungus, Allomyces arbuscula
    J Bacteriol (1988) 170, 1254-1260. PubMed  Europe PubMed  PMC  EPMC

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