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Literature for peptidase C14.013: caspase-12

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

(Topics flags: M Mutation, P Specificity, R Splicing, K Knockout, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2023
  1. Sahoo,G., Samal,D., Khandayataray,P. and Murthy,M.K.<br>A Review on Caspases: Key Regulators of Biological Activities and Apoptosis<br>Mol Neurobiol (2023) 60, 5805-5837. PubMed  Europe PubMed DOI  V
    2. 2021
  2. Hetz,C., Russelakis-Carneiro,M., Maundrell,K., Castilla,J. and Soto,C.<br>Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein<br>EMBO J (2021) 40, e109151-e109151. PubMed  Europe PubMed DOI  PMC  EPMC
    3. 2020
  3. Liu,L., Chen,M., Lin,K., Xiang,X., Zheng,Y. and Zhu,S.<br>Inhibiting Caspase-12 Mediated Inflammasome Activation protects against Oxygen-Glucose Deprivation Injury in Primary Astrocytes<br>Int J Med Sci (2020) 17, 1936-1945. PubMed  Europe PubMed DOI  PMC  EPMC
    4. 2019
  4. Salvamoser,R., Brinkmann,K., O'Reilly,L.A., Whitehead,L., Strasser,A. and Herold,M.J.<br>Characterisation of mice lacking the inflammatory caspases-1/11/12 reveals no contribution of caspase-12 to cell death and sepsis<br>Cell Death Differ (2019) 26, 1124-1137. PubMed  Europe PubMed DOI
    5. 2018
  5. Song,J., Zhang,Q., Wang,S., Yang,F., Chen,Z., Dong,Q., Ji,Q., Yuan,X. and Ren,D.<br>Cleavage of caspase-12 at Asp94, mediated by endoplasmic reticulum stress (ERS), contributes to stretch-induced apoptosis of myoblasts<br>J Cell Physiol (2018) 233, 9473-9487. PubMed  Europe PubMed DOI
    6. 2014
  6. Chen,J., Wilson,E.S., Dahmer,M.K., Quasney,M.W., Waterer,G.W., Feldman,C. and Wunderink,R.G.<br>Lack of association of the caspase-12 long allele with community-acquired pneumonia in people of African descent<br>PLoS ONE (2014) 9, e89194-e89194. PubMed  Europe PubMed DOI  PMC  EPMC
  7. Moorwood,C. and Barton,E.R.<br>Caspase-12 ablation preserves muscle function in the mdx mouse<br>Hum Mol Genet (2014) 23, 5325-5341. PubMed  Europe PubMed DOI  K
  8. Roy,S., Sharom,J.R., Houde,C., Loisel,T.P., Vaillancourt,J.P., Shao,W., Saleh,M. and Nicholson,D.W.<br>Correction for Roy et al., Confinement of caspase-12 proteolytic activity to autoprocessing<br>Proc Natl Acad Sci U S A (2014) DOI
    9. 2012
  9. Kersse,K. and Vandenabeele,P.<br>Caspase-12<br>[ISSN:978-0-12-407743-0] (2012) 3, 2274-2280. DOI
    10. 2011
  10. Hermel,E. and Klapstein,K.D.<br>A possible mechanism for maintenance of the deleterious allele of human CASPASE-12<br>Med Hypotheses (2011) 77, 803-806. PubMed  Europe PubMed DOI
  11. Quiroz-Baez,R., Ferrera,P., Rosendo-Gutierrez,R., Moran,J., Bermudez-Rattoni,F. and Arias,C.<br>Caspase-12 activation is involved in amyloid-beta protein-induced synaptic toxicity<br>J Alzheimers Dis (2011) 26, 467-476. PubMed  Europe PubMed DOI
    12. 2010
  12. Labbe,K., Miu,J., Yeretssian,G., Serghides,L., Tam,M., Finney,C.A., Erdman,L.K., Goulet,M.L., Kain,K.C., Stevenson,M.M. and Saleh,M.<br>Caspase-12 dampens the immune response to malaria independently of the inflammasome by targeting NF-kappaB signaling<br>J Immunol (2010) 185, 5495-5502. PubMed  Europe PubMed DOI
  13. Lee,H.J., Lee,S.H., Park,S.H., Sharoar,M.G., Shin,S.Y., Lee,J.S., Cho,B. and Park,I.S.<br>Purification of catalytically active caspase-12 and its biochemical characterization<br>Arch Biochem Biophys (2010) 502, 68-73. PubMed  Europe PubMed DOI
  14. McCall,M.B., Ferwerda,B., Hopman,J., Ploemen,I., Maiga,B., Daou,M., Dolo,A., Hermsen,C.C., Doumbo,O.K., Bedu-Addo,G., van der Meer,J.W., Troye-Blomberg,M., van der Ven,A.J., Schumann,R.R., Sauerwein,R.W., Mockenhaupt,F.P. and Netea,M.G.<br>Persistence of full-length caspase-12 and its relation to malaria in West and Central African populations<br>Eur Cytokine Netw (2010) 21, 77-83. PubMed  Europe PubMed DOI
  15. Wang,P., Arjona,A., Zhang,Y., Sultana,H., Dai,J., Yang,L., Leblanc,P.M., Doiron,K., Saleh,M. and Fikrig,E.<br>Caspase-12 controls West Nile virus infection via the viral RNA receptor RIG-I<br>Nat Immunol (2010) 11, 912-919. PubMed  Europe PubMed DOI
  16. Yazdi,A.S., Guarda,G., D'Ombrain,M.C. and Drexler,S.K.<br>Inflammatory caspases in innate immunity and inflammation<br>J Innate Immun (2010) 2, 228-237. PubMed  Europe PubMed DOI
    17. 2009
  17. Eckhart,L., Ballaun,C., Uthman,A., Gawlas,S., Buchberger,M., Fischer,H. and Tschachler,E.<br>Duplication of the caspase-12 prodomain and inactivation of NLRC4/IPAF in the dog<br>Biochem Biophys Res Commun (2009) 384, 226-230. PubMed  Europe PubMed DOI  R
  18. Ferwerda,B., McCall,M.B., de Vries,M.C., Hopman,J., Maiga,B., Dolo,A., Doumbo,O., Daou,M., de Jong,D., Joosten,L.A., Tissingh,R.A., Reubsaet,F.A., Sauerwein,R., van der Meer,J.W., van der Ven,A.J. and Netea,M.G.<br>Caspase-12 and the inflammatory response to Yersinia pestis<br>PLoS ONE (2009) 4, e6870-e6870. PubMed  Europe PubMed DOI  PMC  EPMC  M
    19. 2008
  19. Leblanc,P.M., Yeretssian,G., Rutherford,N., Doiron,K., Nadiri,A., Zhu,L., Green,D.R., Gruenheid,S. and Saleh,M.<br>Caspase-12 modulates NOD signaling and regulates antimicrobial peptide production and mucosal immunity<br>Cell Host Microbe (2008) 3, 146-157. PubMed  Europe PubMed DOI
  20. Roy,S., Sharom,J.R., Houde,C., Loisel,T.P., Vaillancourt,J.P., Shao,W., Saleh,M. and Nicholson,D.W.<br>Confinement of caspase-12 proteolytic activity to autoprocessing<br>Proc Natl Acad Sci U S A (2008) 105, 4133-4138. PubMed  Europe PubMed DOI  PMC  EPMC  P
    21. 2007
  21. Kersse,K., Vanden Berghe,T., Lamkanfi,M. and Vandenabeele,P.<br>A phylogenetic and functional overview of inflammatory caspases and caspase-1-related CARD-only proteins<br>Biochem Soc Trans (2007) 35, 1508-1511. PubMed  Europe PubMed DOI
  22. Martinon,F. and Tschopp,J.<br>Inflammatory caspases and inflammasomes: master switches of inflammation<br>Cell Death Differ (2007) 14, 10-22. PubMed  Europe PubMed DOI
  23. Scott,A.M. and Saleh,M.<br>The inflammatory caspases: guardians against infections and sepsis<br>Cell Death Differ (2007) 14, 23-31. PubMed  Europe PubMed DOI
  24. Sharma,R. and Gow,A.<br>Minimal role for caspase 12 in the unfolded protein response in oligodendrocytes in vivo<br>J Neurochem (2007) 101, 889-897. PubMed  Europe PubMed DOI
    25. 2006
  25. [YEAR:17-8-2006]Kachapati,K., O'Brien,T.R., Bergeron,J., Zhang,M. and Dean,M.<br>Population distribution of the functional caspase-12 allele<br>Hum Mutat (17-8-2006) 27, 975-975. PubMed  Europe PubMed DOI  M
  26. [YEAR:15-10-2006]Matzno,S., Yasuda,S., Kitada,Y., Akiyoshi,T., Tanaka,N., Juman,S., Shinozuka,K., Nakabayashi,T. and Matsuyama,K.<br>Clofibrate-induced apoptosis is mediated by Ca2+-dependent caspase-12 activation<br>Life Sci (15-10-2006) 78, 1892-1899. PubMed  Europe PubMed DOI
  27. [YEAR:20-4-2006]Saleh,M., Mathison,J.C., Wolinski,M.K., Bensinger,S.J., Fitzgerald,P., Droin,N., Ulevitch,R.J., Green,D.R. and Nicholson,D.W.<br>Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice<br>Nature (20-4-2006) 440, 1064-1068. PubMed  Europe PubMed DOI  K
  28. Xue,Y., Daly,A., Yngvadottir,B., Liu,M., Coop,G., Kim,Y., Sabeti,P., Chen,Y., Stalker,J., Huckle,E., Burton,J., Leonard,S., Rogers,J. and Tyler-Smith,C.<br>Spread of an inactive form of caspase-12 in humans is due to recent positive selection<br>Am J Hum Genet (2006) 78, 659-670. PubMed  Europe PubMed DOI  PMC  EPMC
    29. 2005
  29. [YEAR:2-2-2005]Aoyama,K., Burns,D.M., Suh,S.W., Garnier,P., Matsumori,Y., Shiina,H. and Swanson,R.A.<br>Acidosis causes endoplasmic reticulum stress and caspase-12-mediated astrocyte death<br>J Cereb Blood Flow Metab (2-2-2005) 25, 358-370. PubMed  Europe PubMed DOI
  30. [YEAR:14-7-2005]Jiang,S., Xie,Q., Zhang,W., Zhou,X.Q. and Jin,Y.X.<br>Preparation of anti-mouse caspase-12 mRNA hammerhead ribozyme and identification of its activity in vitro<br>World J Gastroenterol (14-7-2005) 11, 4094-4097. PubMed  Europe PubMed  K
  31. [YEAR:15-2-2005]Oubrahim,H., Wang,J., Stadtman,E.R. and Chock,P.B.<br>Molecular cloning and characterization of murine caspase-12 gene promoter<br>Proc Natl Acad Sci U S A (15-2-2005) 102, 2322-2327. PubMed  Europe PubMed DOI  PMC  EPMC
    32. 2004
  32. [YEAR:8-10-2004]Hoppe,V. and Hoppe,J.<br>Mutations dislocate caspase-12 from the endoplasmatic reticulum to the cytosol<br>FEBS Lett (8-10-2004) 576, 277-283. PubMed  Europe PubMed DOI
  33. [YEAR:1-4-2004]Kerrigan,S.W., Gaur,M., Murphy,R.P., Shattil,S.J. and Leavitt,A.D.<br>Caspase-12: a developmental link between G-protein-coupled receptors and integrin alphaIIbbeta3 activation<br>Blood (1-4-2004) 104, 1327-1334. PubMed  Europe PubMed DOI
  34. [YEAR:12-12-2004]Lamkanfi,M., Kalai,M. and Vandenabeele,P.<br>Caspase-12: an overview<br>Cell Death Differ (12-12-2004) 11, 365-368. PubMed  Europe PubMed DOI
  35. Saleh,M., Vaillancourt,J.P., Graham,R.K., Huyck,M., Srinivasula,S.M., Alnemri,E.S., Steinberg,M.H., Nolan,V., Baldwin,C.T., Hotchkiss,R.S., Buchman,T.G., Zehnbauer,B.A., Hayden,M.R., Farrer,L.A., Roy,S. and Nicholson,D.W.<br>Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms<br>Nature (2004) 429, 75-79. PubMed  Europe PubMed DOI
    36. 2003
  36. [YEAR:15-10-2003]Hetz,C., Russelakis-Carneiro,M., Maundrell,K., Castilla,J. and Soto,C.<br>Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein<br>EMBO J (15-10-2003) 22, 5435-5445. PubMed  Europe PubMed DOI  PMC  EPMC
  37. [YEAR:4-8-2003]Kalai,M., Lamkanfi,M., Denecker,G., Boogmans,M., Lippens,S., Meeus,A., Declercq,W. and Vandenabeele,P.<br>Regulation of the expression and processing of caspase-12<br>J Cell Biol (4-8-2003) 162, 457-467. PubMed  Europe PubMed DOI  PMC  EPMC
  38. [YEAR:10-2-2003]Mouw,G., Zechel,J.L., Gamboa,J., Lust,W.D., Selman,W.R. and Ratcheson,R.A.<br>Activation of caspase-12, an endoplasmic reticulum resident caspase, after permanent focal ischemia in rat<br>Neuroreport (10-2-2003) 14, 183-186. PubMed  Europe PubMed DOI
  39. Shibata,M., Hattori,H., Sasaki,T., Gotoh,J., Hamada,J. and Fukuuchi,Y.<br>Activation of caspase-12 by endoplasmic reticulum stress induced by transient middle cerebral artery occlusion in mice<br>Neuroscience (2003) 118, 491-499. PubMed  Europe PubMed DOI
    40. 2002
  40. Fujita,E., Kouroku,Y., Jimbo,A., Isoai,A., Maruyama,K. and Momoi,T.<br>Caspase-12 processing and fragment translocation into nuclei of tunicamycin-treated cells<br>Cell Death Differ (2002) 9, 1108-1114. PubMed  Europe PubMed DOI
    41. 2001
  41. Bitko,V. and Barik,S.<br>An endoplasmic reticulum-specific stress-activated caspase (caspase-12) is implicated in the apoptosis of A549 epithelial cells by respiratory syncytial virus<br>J Cell Biochem (2001) 80, 441-454. PubMed  Europe PubMed DOI
  42. [YEAR:27-4-2001]Yoneda,T., Imaizumi,K., Oono,K., Yui,D., Gomi,F., Katayama,T. and Tohyama,M.<br>Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress<br>J Biol Chem (27-4-2001) 276, 13935-13940. PubMed  Europe PubMed DOI
    43. 2000
  43. [YEAR:6-1-2000]Nakagawa,T., Zhu,H., Morishima,N., Li,E., Xu,J., Yankner,B.A. and Yuan,J.<br>Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta<br>Nature (6-1-2000) 403, 98-103. PubMed  Europe PubMed DOI
  44. [YEAR:21-8-2000]Nakagawa,T. and Yuan,J.<br>Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis<br>J Cell Biol (21-8-2000) 150, 887-894. PubMed  Europe PubMed DOI  PMC  EPMC
    45. 1999
  45. Van de Craen,M., Declercq,W., van den Brande,I., Fiers,W. and Vandenabeele,P.<br>The proteolytic procaspase activation network: an in vitro analysis<br>Cell Death Differ (1999) 6, 1117-1124. PubMed  Europe PubMed DOI

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