Literature for peptidase C14.008: caspase-5

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates Pharma

(Topics flags: A Assay, M Mutation, I Inhibitor, P Specificity, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2024
  1. Ai,Y., Meng,Y., Yan,B., Zhou,Q. and Wang,X.<br>The biochemical pathways of apoptotic, necroptotic, pyroptotic, and ferroptotic cell death<br>Mol Cell (2024) 84, 170-179. PubMed  Europe PubMed DOI  V
  2. Eckhart,L. and Fischer,H.<br>Caspase-5: Structure, Pro-Inflammatory Activity and Evolution<br>Biomolecules (2024) 14 PubMed  Europe PubMed DOI  PMC  EPMC  V
  3. 2023
  4. Hisama,F.M., Pillai,R.K., Sidorova,J., Patterson,K., Gokingco,C., Yacobi-Bach,M. and Oshima,J.<br>Caspase 5 depletion is linked to hyper-inflammatory response and progeroid syndrome<br>Geroscience (2023) PubMed  Europe PubMed DOI
  5. Sahoo,G., Samal,D., Khandayataray,P. and Murthy,M.K.<br>A Review on Caspases: Key Regulators of Biological Activities and Apoptosis<br>Mol Neurobiol (2023) 60, 5805-5837. PubMed  Europe PubMed DOI  V
  6. Shi,X., Sun,Q., Hou,Y., Zeng,H., Cao,Y., Dong,M., Ding,J. and Shao,F.<br>Recognition and maturation of IL-18 by caspase-4 noncanonical inflammasome<br>Nature (2023) 624, 442-450. PubMed  Europe PubMed DOI
  7. 2022
  8. Ross,C., Chan,A.H., von Pein,J.B., Maddugoda,M.P., Boucher,D. and Schroder,K.<br>Inflammatory Caspases: Toward a Unified Model for Caspase Activation by Inflammasomes<br>Annu Rev Immunol (2022) PubMed  Europe PubMed DOI  V
  9. Smith,A.P. and Creagh,E.M.<br>Caspase-4 and -5 Biology in the Pathogenesis of Inflammatory Bowel Disease<br>Front Pharmacol (2022) 13, 919567-919567. PubMed  Europe PubMed DOI  PMC  EPMC  V
  10. Wang,Z., Chan,W. and Yue,Y.<br>A significant other: Non-canonical caspase-4/5/11 inflammasome in periodontitis<br>Oral Dis (2022) PubMed  Europe PubMed DOI  V
  11. 2021
  12. Bateman,G., Hill,B., Knight,R. and Boucher,D.<br>Great balls of fire: activation and signalling of inflammatory caspases<br>Biochem Soc Trans (2021) 49, 1311-1324. PubMed  Europe PubMed DOI  V
  13. 2020
  14. Hong,W., Gu,Y., Guan,R., Xie,D., Zhou,H. and Yu,M.<br>Pan-cancer analysis of the CASP gene family in relation to survival, tumor-infiltrating immune cells and therapeutic targets<br>Genomics (2020) PubMed  Europe PubMed DOI
  15. 2016
  16. Julien,O., Zhuang,M., Wiita,A.P., O'Donoghue,A.J., Knudsen,G.M., Craik,C.S. and Wells,J.A.<br>Quantitative MS-based enzymology of caspases reveals distinct protein substrate specificities, hierarchies, and cellular roles<br>Proc Natl Acad Sci U S A (2016) 113, E2001-E2010. PubMed  Europe PubMed DOI  P
  17. Kent,C.R., Bryja,M., Gustafson,H.A., Kawarski,M.Y., Lenti,G., Pierce,E.N., Knopp,R.C., Ceja,V., Pati,B., Walters,D.E. and Karver,C.E.<br>Variation of the aryl substituent on the piperazine ring within the 4-(piperazin-1-yl)-2,6-di(pyrrolidin-1-yl)pyrimidine scaffold unveils potent, non-competitive inhibitors of the inflammatory caspases<br>Bioorg Med Chem Lett (2016) 26, 5476-5480. PubMed  Europe PubMed DOI  I
  18. 2015
  19. Shi,J., Zhao,Y., Wang,K., Shi,X., Wang,Y., Huang,H., Zhuang,Y., Cai,T., Wang,F. and Shao,F.<br>Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death<br>Nature (2015) 526, 660-665. PubMed  Europe PubMed DOI
  20. 2012
  21. Gao,J. and Wells,J.A.<br>Identification of specific tethered inhibitors for caspase-5<br>Chem Biol Drug Des (2012) 79, 209-215. PubMed  Europe PubMed DOI  I
  22. Gao,J. and Wells,J.A.<br>Caspase-4 and caspase-5<br>[ISSN:978-0-12-407743-0] (2012) 3, 2265-2269. DOI
  23. Roschitzki-Voser,H., Schroeder,T., Lenherr,E.D., Frolich,F., Schweizer,A., Donepudi,M., Ganesan,R., Mittl,P.R., Baici,A. and Grutter,M.G.<br>Human caspases in vitro: expression, purification and kinetic characterization<br>Protein Expr Purif (2012) 84, 236-246. PubMed  Europe PubMed DOI  E
  24. 2011
  25. Lopez,D., Jimenez,M., Garcia-Calvo,M. and Del Val,M.<br>Concerted antigen processing of a short viral antigen by human caspase-5 and -10<br>J Biol Chem (2011) 286, 16910-16913. PubMed  Europe PubMed DOI
  26. 2010
  27. Agard,N.J., Maltby,D. and Wells,J.A.<br>Inflammatory stimuli regulate caspase substrate profiles<br>Mol Cell Proteomics (2010) 9, 880-893. PubMed  Europe PubMed DOI  P
  28. Haripriya,M., Rambabu,G. and Jagarlapudi,S.<br>Modeling of human caspase-5 protein and docking studies of caspase-5 inhibitors against modeled caspase-5<br>J Global Pharma Technol (2010) 2, 13-26.
  29. Yazdi,A.S., Guarda,G., D'Ombrain,M.C. and Drexler,S.K.<br>Inflammatory caspases in innate immunity and inflammation<br>J Innate Immun (2010) 2, 228-237. PubMed  Europe PubMed DOI
  30. 2009
  31. Benkova,B., Lozanov,V., Ivanov,I.P. and Mitev,V.<br>Evaluation of recombinant caspase specificity by competitive substrates<br>Anal Biochem (2009) 394, 68-74. PubMed  Europe PubMed DOI  A  P
  32. 2008
  33. Soung,Y.H., Jeong,E.G., Ahn,C.H., Kim,S.S., Song,S.Y., Yoo,N.J. and Lee,S.H.<br>Mutational analysis of caspase 1, 4, and 5 genes in common human cancers<br>Hum Pathol (2008) 39, 895-900. PubMed  Europe PubMed DOI  M
  34. 2007
  35. Kersse,K., Vanden Berghe,T., Lamkanfi,M. and Vandenabeele,P.<br>A phylogenetic and functional overview of inflammatory caspases and caspase-1-related CARD-only proteins<br>Biochem Soc Trans (2007) 35, 1508-1511. PubMed  Europe PubMed DOI
  36. Martinon,F. and Tschopp,J.<br>Inflammatory caspases and inflammasomes: master switches of inflammation<br>Cell Death Differ (2007) 14, 10-22. PubMed  Europe PubMed DOI
  37. 2006
  38. [YEAR:22-9-2006]Eckhart,L., Kittel,C., Gawlas,S., Gruber,F., Mildner,M., Jilma,B. and Tschachler,E.<br>Identification of a novel exon encoding the amino-terminus of the predominant caspase-5 variants<br>Biochem Biophys Res Commun (22-9-2006) 348, 682-688. PubMed  Europe PubMed DOI
  39. 2003
  40. Hosomi,Y., Gemma,A., Hosoya,Y., Nara,M., Okano,T., Takenaka,K., Yoshimura,A., Koizumi,K., Shimizu,K. and Kudoh,S.<br>Somatic mutation of the caspase-5 gene in human lung cancer<br>Int J Mol Med (2003) 12, 443-446. PubMed  Europe PubMed  M
  41. 2000
  42. [YEAR:22-12-2000]Lin,X.Y., Choi,M.S. and Porter,A.G.<br>Expression analysis of the human caspase-1 subfamily reveals specific regulation of the CASP5 gene by lipopolysaccharide and interferon-gamma<br>J Biol Chem (22-12-2000) 275, 39920-39926. PubMed  Europe PubMed DOI
  43. 1999
  44. Garcia-Calvo,M., Peterson,E.P., Rasper,D.M., Vaillancourt,J.P., Zamboni,R., Nicholson,D.W. and Thornberry,N.A.<br>Purification and catalytic properties of human caspase family members<br>Cell Death Differ (1999) 6, 362-369. PubMed  Europe PubMed DOI
  45. 1998
  46. [YEAR:1-4-1998]Fassy,F., Krebs,O., Rey,H., Komara,B., Gillard,C., Capdevila,C., Yea,C., Faucheu,C., Blanchet,A.M., Miossec,C. and Diu-Hercend,A.<br>Enzymatic activity of two caspases related to interleukin-1beta-converting enzyme<br>Eur J Biochem (1-4-1998) 253, 76-83. PubMed  Europe PubMed DOI
  47. 1997
  48. Kamada,S., Funahashi,Y. and Tsujimoto,Y.<br>Caspase-4 and caspase-5, members of the ICE/CED-3 family of cysteine proteases, are CrmA-inhibitable proteases<br>Cell Death Differ (1997) 4, 473-478. PubMed  Europe PubMed DOI  I
  49. 1996
  50. Wang,S., Miura,M., Jung,Y., Zhu,H., Gagliardini,V., Shi,L., Greenberg,A.H. and Yuan,J.<br>Identification and characterization of Ich-3, a member of the interleukin-1beta converting enzyme (ICE)/Ced-3 family and an upstream regulator of ICE<br>J Biol Chem (1996) 271, 20580-20587. PubMed  Europe PubMed DOI